Title:
METHOD AND SYSTEM FOR PREDICTING SPATIAL AND TEMPORAL DISTRIBUTIONS OF THERAPEUTIC SUBSTANCE CARRIERS
Document Type and Number:
WIPO Patent Application WO/2015/017798
Kind Code:
A3
Abstract:
A method and system predicts spatial and temporal distributions of therapeutic substance earners within a body of a user, comprising: at a computing system, receiving an image dataset and a spectra dataset of a therapeutic substance carrier generated from at least one of an imaging model and a spectra-generating module; transforming the image dataset and the spectra dataset into a set of characteristics, wherein the set of characteristics comprises electrotopological characteristics and geometrical characteristics; generating a set of pharmacokinetic parameters and a set of pharmacodynamic parameters for the therapeutic substance carrier based upon the set of characteristics and a transformation model; and transforming the set of pharmacokinetic parameters and the set of pharmacodynamic parameters into a spatial distribution and a temporal profile of the therapeutic substance carrier, based upon a predictive model incorporating physiological parameters of the body, thereby predicting distributions of the therapeutic substance carrier within the body.
Inventors:
ANANDA YOGENDRAN SHALINI (US)
Application Number:
PCT/US2014/049437
Publication Date:
April 09, 2015
Filing Date:
August 01, 2014
Export Citation:
Assignee:
CRIXLABS INC (US)
International Classes:
G01N31/22; G01N33/53; G06F19/16
Foreign References:
| US20050089923A9 | 2005-04-28 | |||
| US20060282236A1 | 2006-12-14 | |||
| US20030215877A1 | 2003-11-20 | |||
| US20030130797A1 | 2003-07-10 |
Attorney, Agent or Firm:
SCHOX, Jeffrey (500 3rd Street Suite 51, San Francisco CA, US)
Download PDF: