Title:
METHOD AND SYSTEM FOR VERIFYING A TEMPERATURE MEASUREMENT IN A MICRO-ENVIRONMENT
Document Type and Number:
WIPO Patent Application WO/2013/057308
Kind Code:
A3
Abstract:
The present invention pertains to a method suitable for analysing the temperature control of a device which is supposed to establish a defined temperature in a micro-environment, said method comprising a first Optical Temperature Verification step which comprises a) providing one or more thermochromatic liquid crystals in a micro-environment, wherein each thermochromatic liquid crystal has a specific event temperature; b) providing one or more temperature dependent luminophores in a micro-environment; c) varying the temperature in the micro-environments and irradiating the micro-environments with light; d) recording the luminescence of the one or more temperature dependent luminophores when the event temperature of the one or more thermochromatic liquid crystals is reached in the micro-environment; and wherein said method preferably comprises a second Optical Temperature Verification step, which comprises the following: a) providing one or more temperature dependent luminophores that were used in the First Optical Temperature Verification in a micro-environment; b) varying the temperature of the micro-environments and irradiating the micro-environments with light; c) monitoring the luminescence emitted. The respective method is very suitable to analyse the temperature control of a thermal cycler, in particular during a calibration.
Inventors:
LEBER DIRK (CH)
BÄHLER STEPHAN (CH)
MEYER HANSUELI (CH)
BÄHLER STEPHAN (CH)
MEYER HANSUELI (CH)
Application Number:
PCT/EP2012/070856
Publication Date:
July 10, 2014
Filing Date:
October 22, 2012
Export Citation:
Assignee:
QIAGEN INSTR AG (CH)
International Classes:
G01K11/20; G01K11/16; G01K15/00
Domestic Patent References:
| WO2003102522A1 | 2003-12-11 |
Foreign References:
| DD270448A3 | 1989-08-02 | |||
| US3142755A | 1964-07-28 |
Other References:
See also references of EP 2769189A2
Attorney, Agent or Firm:
ROTH, Carla et al. (Patentanwälte Partnerschaft mbBMönchenwerther Strasse 11, Düsseldorf, DE)
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