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Title:
METHOD AND SYSTEMS FOR THE NON-INVASIVE OPTICAL CHARACTERIZATION OF A HETEROGENEOUS MEDIUM
Document Type and Number:
WIPO Patent Application WO/2020/016249
Kind Code:
A3
Abstract:
The present invention relates to a method for the non-invasive optical characterization of a heterogeneous medium, comprising: a step of illuminating, by means of a series of incident light waves, a given field of vision of the heterogeneous medium, which is positioned in a focal plane of the lens (30) of a microscope; a step of determining a first distortion matrix (Dur, Drr) in an observation basis defined between a conjugated plane of the focal plane (FP) and an observation plane, said first distortion matrix corresponding, in a correction basis defined between a conjugated plane of the focal plane and an aberration correction plane, to the term-by-term matrix product of a first reflection matrix (Rur) of the field of vision, determined in the correction basis, by means of the phase conjugated matrix of a reference reflection matrix, defined for a model medium, in said correction basis; and a step of determining, from the first distortion matrix, at least one cartography of a physical parameter of the heterogeneous medium.

Inventors:
AUBRY ALEXANDRE (FR)
BADON AMAURY (US)
BAROLLE VICTOR (FR)
BOCCARA CLAUDE (FR)
COBUS LAURA (FR)
FINK MATHIAS (FR)
LAMBERT WILLIAM (FR)
Application Number:
PCT/EP2019/069158
Publication Date:
February 27, 2020
Filing Date:
July 16, 2019
Export Citation:
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Assignee:
CENTRE NAT RECH SCIENT (FR)
ECOLE SUPERIEURE PHYSIQUE & CHIMIE IND VILLE DE PARIS (FR)
International Classes:
G01N21/00; G10B1/00
Domestic Patent References:
WO2013068783A12013-05-16
Foreign References:
US20160061725A12016-03-03
Other References:
YU ET AL: "Measuring large optical reflection matrices of turbid media", OPTICS COMMUNICATIONS,, vol. 352, 29 April 2015 (2015-04-29), pages 33 - 38, XP002791865
DUBOIS A ET AL: "High-resolution full-field optical coherence tomography with a Linnik microscope", APPLIED OPTICS, OPTICAL SOCIETY OF AMERICA, WASHINGTON, DC; US, vol. 41, no. 4, 1 February 2002 (2002-02-01), pages 805 - 812, XP002373646, ISSN: 0003-6935, DOI: 10.1364/AO.41.000805
YANG QIANG ET AL: "Deep imaging in highly scattering media by combining reflection matrix measurement with Bessel-like beam based optical coherence tomography", APPLIED PHYSICS LETTERS, A I P PUBLISHING LLC, US, vol. 113, no. 1, 3 July 2018 (2018-07-03), XP012229815, ISSN: 0003-6951, [retrieved on 20180703], DOI: 10.1063/1.5036661
Attorney, Agent or Firm:
OSHA LIANG (FR)
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