Title:
METHOD AND SYSTEMS FOR THE NON-INVASIVE OPTICAL CHARACTERIZATION OF A HETEROGENEOUS MEDIUM
Document Type and Number:
WIPO Patent Application WO/2020/016249
Kind Code:
A3
Abstract:
The present invention relates to a method for the non-invasive optical characterization of a heterogeneous medium, comprising: a step of illuminating, by means of a series of incident light waves, a given field of vision of the heterogeneous medium, which is positioned in a focal plane of the lens (30) of a microscope; a step of determining a first distortion matrix (Dur, Drr) in an observation basis defined between a conjugated plane of the focal plane (FP) and an observation plane, said first distortion matrix corresponding, in a correction basis defined between a conjugated plane of the focal plane and an aberration correction plane, to the term-by-term matrix product of a first reflection matrix (Rur) of the field of vision, determined in the correction basis, by means of the phase conjugated matrix of a reference reflection matrix, defined for a model medium, in said correction basis; and a step of determining, from the first distortion matrix, at least one cartography of a physical parameter of the heterogeneous medium.
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Inventors:
AUBRY ALEXANDRE (FR)
BADON AMAURY (US)
BAROLLE VICTOR (FR)
BOCCARA CLAUDE (FR)
COBUS LAURA (FR)
FINK MATHIAS (FR)
LAMBERT WILLIAM (FR)
BADON AMAURY (US)
BAROLLE VICTOR (FR)
BOCCARA CLAUDE (FR)
COBUS LAURA (FR)
FINK MATHIAS (FR)
LAMBERT WILLIAM (FR)
Application Number:
PCT/EP2019/069158
Publication Date:
February 27, 2020
Filing Date:
July 16, 2019
Export Citation:
Assignee:
CENTRE NAT RECH SCIENT (FR)
ECOLE SUPERIEURE PHYSIQUE & CHIMIE IND VILLE DE PARIS (FR)
ECOLE SUPERIEURE PHYSIQUE & CHIMIE IND VILLE DE PARIS (FR)
International Classes:
G01N21/00; G10B1/00
Domestic Patent References:
WO2013068783A1 | 2013-05-16 |
Foreign References:
US20160061725A1 | 2016-03-03 |
Other References:
YU ET AL: "Measuring large optical reflection matrices of turbid media", OPTICS COMMUNICATIONS,, vol. 352, 29 April 2015 (2015-04-29), pages 33 - 38, XP002791865
DUBOIS A ET AL: "High-resolution full-field optical coherence tomography with a Linnik microscope", APPLIED OPTICS, OPTICAL SOCIETY OF AMERICA, WASHINGTON, DC; US, vol. 41, no. 4, 1 February 2002 (2002-02-01), pages 805 - 812, XP002373646, ISSN: 0003-6935, DOI: 10.1364/AO.41.000805
YANG QIANG ET AL: "Deep imaging in highly scattering media by combining reflection matrix measurement with Bessel-like beam based optical coherence tomography", APPLIED PHYSICS LETTERS, A I P PUBLISHING LLC, US, vol. 113, no. 1, 3 July 2018 (2018-07-03), XP012229815, ISSN: 0003-6951, [retrieved on 20180703], DOI: 10.1063/1.5036661
DUBOIS A ET AL: "High-resolution full-field optical coherence tomography with a Linnik microscope", APPLIED OPTICS, OPTICAL SOCIETY OF AMERICA, WASHINGTON, DC; US, vol. 41, no. 4, 1 February 2002 (2002-02-01), pages 805 - 812, XP002373646, ISSN: 0003-6935, DOI: 10.1364/AO.41.000805
YANG QIANG ET AL: "Deep imaging in highly scattering media by combining reflection matrix measurement with Bessel-like beam based optical coherence tomography", APPLIED PHYSICS LETTERS, A I P PUBLISHING LLC, US, vol. 113, no. 1, 3 July 2018 (2018-07-03), XP012229815, ISSN: 0003-6951, [retrieved on 20180703], DOI: 10.1063/1.5036661
Attorney, Agent or Firm:
OSHA LIANG (FR)
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