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Title:
METHOD FOR TESTING RISK OF CARDIAC INFARCTION
Document Type and Number:
WIPO Patent Application WO/2012/070510
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a method for testing the risk of (a method for determining susceptibility to) cardiac infarction, which is highly accurate and is clinically useful; and a reagent and a kit, both of which can be used in the method. Provided is a method for testing the risk of cardiac infarction, which involves a step of detecting the occurrence of any one gene polymorphism selected from the items (1) to(5) mentioned below in a nucleic acid sample collected from a subject: (1) a polymorphism for a region encoding a glutamic acid repeat in ALMS1 gene; (2) a single nucleotide polymorphism that is identified as a registration number rs2037814 in the SNP database of the U.S. national center for biotechnology information (NCBI); (3) a single nucleotide polymorphism that is identified as a registration number rs7598901 in the SNP database of the U.S. national center for biotechnology information (NCBI); (4) a single nucleotide polymorphism that is identified as a registration number rs1052161 in the SNP database of the U.S. national center for biotechnology information (NCBI); and (5) a single nucleotide polymorphism that is identified as a registration number rs6706562 in the SNP database of the U.S. national center for biotechnology information (NCBI).

Inventors:
YOKOTA MITSUHIRO (JP)
Application Number:
PCT/JP2011/076738
Publication Date:
May 31, 2012
Filing Date:
November 19, 2011
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Assignee:
YOKOTA MITSUHIRO (JP)
International Classes:
C12N15/09; C12Q1/68
Domestic Patent References:
WO2010010697A12010-01-28
Other References:
SEIKO MIYATA ET AL.: "Genome Ekigaku Kenkyu to Rinsho eno Tenkai Junkanki Bun'ya ni Okeru Kobetsuka Iryo eno Tenkai -Shinkin Kosoku Kanjusei Idenshi no Tansaku", SAISHIN IGAKU, vol. 62, no. 9, September 2007 (2007-09-01), pages 2265 - 2275
Attorney, Agent or Firm:
HAGINO Mikiharu (JP)
Kanji Hagino (JP)
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Claims: