Title:
METHOD TO PREVENT VISION LOSS
Document Type and Number:
WIPO Patent Application WO2002062385
Kind Code:
A3
Abstract:
An improved method to treat conditions of the eye characterized by ocular neovascularization is provided in which patients are given and initial photodynamic therapy (PDT) treatment to destroy the neovasculature, and then are re-evaluated at least twice during the following 6 months, and retreated as necessary. Preferably, three retreatments are provided.
Inventors:
STRONG H ANDREW (CA)
AZAB MOHAMMAD (CA)
REAVES TROY ALBERT JR (US)
AZAB MOHAMMAD (CA)
REAVES TROY ALBERT JR (US)
Application Number:
PCT/US2002/003757
Publication Date:
February 06, 2003
Filing Date:
February 06, 2002
Export Citation:
Assignee:
QUADRA LOGIC TECH INC (CA)
NOVARTIS AG (CH)
STRONG H ANDREW (CA)
AZAB MOHAMMAD (CA)
REAVES TROY ALBERT JR (US)
NOVARTIS AG (CH)
STRONG H ANDREW (CA)
AZAB MOHAMMAD (CA)
REAVES TROY ALBERT JR (US)
International Classes:
A61K41/00; (IPC1-7): A61K41/00
Domestic Patent References:
| WO2002062386A2 | 2002-08-15 | |||
| WO2002062384A2 | 2002-08-15 |
Foreign References:
| US5798349A | 1998-08-25 | |||
| US5198460A | 1993-03-30 |
Other References:
SCHMIDT-ERFURTH U ET AL: "Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-related macular degeneration: results of retreatments in a phase 1 and 2 study.", ARCHIVES OF OPHTHALMOLOGY. UNITED STATES SEP 1999, vol. 117, no. 9, September 1999 (1999-09-01), pages 1177 - 1187, XP000853995, ISSN: 0003-9950
SICKENBERG, MICHEL ET AL: "A preliminary study of photodynamic therapy using verteporfin for choroidal neovascularization in pathologic myopia ocular histoplasmosis syndrome, angioid streaks, and idiopathic causes", ARCHIVES OF OPHTHALMOLOGY (CHICAGO) (2000), 118(3), 327-336, XP008010406
SCOTT L J ET AL: "Verteporfin.", DRUGS & AGING. NEW ZEALAND FEB 2000, vol. 16, no. 2, February 2000 (2000-02-01), pages 139 - 146;discussion 147 - 148, XP008010590, ISSN: 1170-229X
"PHOTODYNAMIC THERAPY OF SUBFOVEAL CHOROIDAL NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION WITH VERTEPORFIN", JOURNAL OF NEUROLOGY - ZEITSCHRIFT FUER NEUROLOGIE, SPRINGER VERLAG, BERLIN, DE, vol. 117, no. 10, 1999, pages 1329 - 1345, XP000853866, ISSN: 0340-5354
MICHELS S ET AL: "[Changes in neovascular membranes and normal choroid blood vessels after multiple photodynamic therapy treatments]", DER OPHTHALMOLOGE: ZEITSCHRIFT DER DEUTSCHEN OPHTHALMOLOGISCHEN GESELLSCHAFT. GERMANY FEB 2002, vol. 99, no. 2, February 2002 (2002-02-01), pages 96 - 100, XP001122891, ISSN: 0941-293X
SICKENBERG, MICHEL ET AL: "A preliminary study of photodynamic therapy using verteporfin for choroidal neovascularization in pathologic myopia ocular histoplasmosis syndrome, angioid streaks, and idiopathic causes", ARCHIVES OF OPHTHALMOLOGY (CHICAGO) (2000), 118(3), 327-336, XP008010406
SCOTT L J ET AL: "Verteporfin.", DRUGS & AGING. NEW ZEALAND FEB 2000, vol. 16, no. 2, February 2000 (2000-02-01), pages 139 - 146;discussion 147 - 148, XP008010590, ISSN: 1170-229X
"PHOTODYNAMIC THERAPY OF SUBFOVEAL CHOROIDAL NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION WITH VERTEPORFIN", JOURNAL OF NEUROLOGY - ZEITSCHRIFT FUER NEUROLOGIE, SPRINGER VERLAG, BERLIN, DE, vol. 117, no. 10, 1999, pages 1329 - 1345, XP000853866, ISSN: 0340-5354
MICHELS S ET AL: "[Changes in neovascular membranes and normal choroid blood vessels after multiple photodynamic therapy treatments]", DER OPHTHALMOLOGE: ZEITSCHRIFT DER DEUTSCHEN OPHTHALMOLOGISCHEN GESELLSCHAFT. GERMANY FEB 2002, vol. 99, no. 2, February 2002 (2002-02-01), pages 96 - 100, XP001122891, ISSN: 0941-293X
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