Title:
METHOD FOR TREATING AUTOIMMUNE DISEASE BY IL-17 ANTAGONIST
Document Type and Number:
WIPO Patent Application WO/2021/018191
Kind Code:
A1
Abstract:
The present application relates to a method for treating an autoimmune disease by an IL-17 antagonist. The present application relates to an application of an IL-17A conjugate in preparation of a drug for treating an autoimmune disease, such as rheumatoid arthritis, ankylosing spondylitis, and psoriasis, in particular, provides a method for treating inflammation or an autoimmune disease, comprising administering an effective amount of an IL-17 conjugate to a patient, wherein the administration frequency is less than once a week.
Inventors:
SUN PIAOYANG (CN)
ZHANG LIANSHAN (CN)
CHEN JIANWEN (CN)
XU QIAN (CN)
GAO QUNJIE (CN)
ZHANG LIANSHAN (CN)
CHEN JIANWEN (CN)
XU QIAN (CN)
GAO QUNJIE (CN)
Application Number:
PCT/CN2020/105510
Publication Date:
February 04, 2021
Filing Date:
July 29, 2020
Export Citation:
Assignee:
JIANGSU HENGRUI MEDICINE CO (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
International Classes:
C07K16/24; A61K39/395; A61P19/02; A61P37/02; C12N15/13
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Other References:
AGGARWAL ET AL., J. LEUKOC. BIOL., vol. 71, no. 1, 2002, pages 1 - 8
KABAT, E. A. ET AL.: "Sequences of Proteins of Immunological Interest", 1991
J. METHODS MOL BIOL, vol. 882, 2012, pages 605 - 633
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See also references of EP 4006053A4
KABAT, E. A. ET AL.: "Sequences of Proteins of Immunological Interest", 1991
J. METHODS MOL BIOL, vol. 882, 2012, pages 605 - 633
WARD ET AL., NATURE, vol. 341, 1989, pages 544 - 546
HENSELER TSCHMITT-RAU K, INT. J. DERMATOL., vol. 47, 2008, pages 1019 - 1023
See also references of EP 4006053A4
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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