Title:
METHOD FOR TREATING CANCER USING A33 SPECIFIC ANTIBODIES AND CHEMOTHERAPEUTIC AGENTS
Document Type and Number:
WIPO Patent Application WO2002072008
Kind Code:
A9
Abstract:
This invention relates to a combination of immunotherapy and chemotherapy to promote tumor regression by treating a patient in need thereof with a combination of an antibody that binds to A33 antigen and one or more chemotherapeutic agents. The method is useful for treating patients with colorectal cancer and gastric carcinomas. The method is particularly useful for treating patients who have tumors that are resistant to one or more chemotherapeutic agents and/or have metastasized.
Inventors:
WELT SYDNEY
KEMENY NANCY
RITTER GERD
JUNGBLUTH ACHIM A
OLD LLOYD J
COHEN LEONARD
KEMENY NANCY
RITTER GERD
JUNGBLUTH ACHIM A
OLD LLOYD J
COHEN LEONARD
Application Number:
PCT/US2002/006902
Publication Date:
November 28, 2002
Filing Date:
March 08, 2002
Export Citation:
Assignee:
LUDWIG INST CANCER RES (US)
SLOAN KETTERING INST CANCER (US)
SLOAN KETTERING INST CANCER (US)
International Classes:
A61K39/395; A61K45/06; A61P35/04; C07K16/30; (IPC1-7): A61K/
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