Title:
METHOD FOR TREATING PROLIFERATIVE DISEASES BY THERAPY
Document Type and Number:
WIPO Patent Application WO1999013920
Kind Code:
A3
Abstract:
The invention relates to a method for treating proliferative diseases by therapy, characterised in that an application catheter is first placed at the site of the lesion and a radioactive substance is applied locally. The catheter is then removed, leaving the radioactive substance at the site of the lesion. The invention also relates to the use of bis-amine-oxime derivative, N2S2 complex derivatives and radioactively marked colloidal solutions for producing agents which are applied locally in proliferative disease therapy.
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Inventors:
DINKELBORG LUDGER (DE)
HILGER CHRISTOPH-STEPHAN (DE)
HELDMANN DIETER (DE)
BLUME FRIEDHELM (DE)
HILGER CHRISTOPH-STEPHAN (DE)
HELDMANN DIETER (DE)
BLUME FRIEDHELM (DE)
Application Number:
PCT/EP1998/005741
Publication Date:
May 06, 1999
Filing Date:
September 10, 1998
Export Citation:
Assignee:
SCHERING AG (DE)
DINKELBORG LUDGER (DE)
HILGER CHRISTOPH STEPHAN (DE)
HELDMANN DIETER (DE)
BLUME FRIEDHELM (DE)
DINKELBORG LUDGER (DE)
HILGER CHRISTOPH STEPHAN (DE)
HELDMANN DIETER (DE)
BLUME FRIEDHELM (DE)
International Classes:
A61K51/00; A61K31/145; A61K31/15; A61K31/28; A61K51/12; A61P9/10; A61P35/00; C07B59/00; C07C251/38; C07C323/32; C07F13/00; (IPC1-7): A61K51/12
Domestic Patent References:
| WO1998048851A2 | 1998-11-05 | |||
| WO1998012979A1 | 1998-04-02 | |||
| WO1997038730A2 | 1997-10-23 | |||
| WO1998048852A2 | 1998-11-05 | |||
| WO1998030147A1 | 1998-07-16 |
Other References:
DATABASE MEDLINE US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; NAMBA H ET AL: "Assessment of the brain areas perfused by superselective intra-arterial chemotherapy using single photon emission computed tomography with technetium-99m-hexamethyl-propyleneamine oxime--technical note.", XP002095231
DATABASE MEDLINE US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; AOKI S ET AL: "Supraophthalmic chemotherapy with long tapered catheter: distribution evaluated with intraarterial and intravenous Tc-99m HMPAO.", XP002095232
DATABASE MEDLINE US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; DELGADO R ET AL: "Renal blood flow distribution during steady-state exercise and exhaustion in conscious dogs.", XP002095233
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; SVENDSEN, JESPER H. ET AL: "Capillary permeability of technetium-99m-DTPA in canine myocardium determined by intracoronary bolus injection and residue detection", XP002095265
DATABASE MEDLINE US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; AOKI S ET AL: "Supraophthalmic chemotherapy with long tapered catheter: distribution evaluated with intraarterial and intravenous Tc-99m HMPAO.", XP002095232
DATABASE MEDLINE US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; DELGADO R ET AL: "Renal blood flow distribution during steady-state exercise and exhaustion in conscious dogs.", XP002095233
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; SVENDSEN, JESPER H. ET AL: "Capillary permeability of technetium-99m-DTPA in canine myocardium determined by intracoronary bolus injection and residue detection", XP002095265
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