Title:
METHOD OF TREATING WEIGHT GAIN
Document Type and Number:
WIPO Patent Application WO2000071106
Kind Code:
A3
Abstract:
A method of treating weight in patients, in particular those suffering from psychoses, by administering the antipsychotic agent quetiapine.
Inventors:
REINSTEIN MICHAEL J (US)
JONES ANDREW MARTIN (GB)
JONES ANDREW MARTIN (GB)
Application Number:
PCT/GB2000/001875
Publication Date:
May 10, 2002
Filing Date:
May 16, 2000
Export Citation:
Assignee:
ASTRAZENECA AB (SE)
REINSTEIN MICHAEL J (US)
JONES ANDREW MARTIN (GB)
REINSTEIN MICHAEL J (US)
JONES ANDREW MARTIN (GB)
International Classes:
C07D281/16; A61K31/55; A61K31/554; A61P3/04; A61P25/18; (IPC1-7): A61K31/551; A61K31/554; A61P3/04; A61P25/18
Domestic Patent References:
| WO1998004289A2 | 1998-02-05 | |||
| WO1997032037A1 | 1997-09-04 | |||
| WO2000054764A2 | 2000-09-21 |
Foreign References:
| EP0830864A1 | 1998-03-25 |
Other References:
MISRA L K ET AL: "Quetiapine: a new atypical antipsychotic.", SOUTH DAKOTA JOURNAL OF MEDICINE, (1998 JUN) 51 (6) 189-93. REF: 13, XP000901163
LEYSEN J.E. ET AL: "Receptor interactions of new antipsychotics: Relation to pharmacodynamic and clinical effects.", INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE, (1998) 2/SUPPL. 1 (S3-S17)., XP001009585
ANONYMOUS: "Adverse effects of the atypical antipsychotics. Collaborative Working Group on Clinical Trial Evaluations.", JOURNAL OF CLINICAL PSYCHIATRY, (1998) 59 SUPPL 12 17-22. REF: 57, XP001009550
ROBERTSON J B JR ET AL: "Successful use of high dose quetiapine in a patient with a psychiatric disorder resistant to olanzapine.", EUROPEAN NEUROPSYCHOPHARMACOLOGY, vol. 10, no. Supplement 3, September 2000 (2000-09-01), 13th Congress of the European College of Neuropsychopharmacology;Munich, Germany; September 09-13, 2000, pages S319 - S320, XP001010838, ISSN: 0924-977X
NASR S J: "Resolution of rapid weight gain on olanzapine after substitution with quetiapine.", EUROPEAN NEUROPSYCHOPHARMACOLOGY, vol. 10, no. Supplement 3, September 2000 (2000-09-01), 13th Congress of the European College of Neuropsychopharmacology;Munich, Germany; September 09-13, 2000, pages S319, XP001009548, ISSN: 0924-977X
REINSTEIN MICHAEL J ET AL: "Effect of clozapine-quetiapine combination therapy on weight and glycaemic control: Preliminary findings.", CLINICAL DRUG INVESTIGATION, vol. 18, no. 2, August 1999 (1999-08-01), pages 99 - 104, XP001009552, ISSN: 1173-2563
LEYSEN J.E. ET AL: "Receptor interactions of new antipsychotics: Relation to pharmacodynamic and clinical effects.", INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE, (1998) 2/SUPPL. 1 (S3-S17)., XP001009585
ANONYMOUS: "Adverse effects of the atypical antipsychotics. Collaborative Working Group on Clinical Trial Evaluations.", JOURNAL OF CLINICAL PSYCHIATRY, (1998) 59 SUPPL 12 17-22. REF: 57, XP001009550
ROBERTSON J B JR ET AL: "Successful use of high dose quetiapine in a patient with a psychiatric disorder resistant to olanzapine.", EUROPEAN NEUROPSYCHOPHARMACOLOGY, vol. 10, no. Supplement 3, September 2000 (2000-09-01), 13th Congress of the European College of Neuropsychopharmacology;Munich, Germany; September 09-13, 2000, pages S319 - S320, XP001010838, ISSN: 0924-977X
NASR S J: "Resolution of rapid weight gain on olanzapine after substitution with quetiapine.", EUROPEAN NEUROPSYCHOPHARMACOLOGY, vol. 10, no. Supplement 3, September 2000 (2000-09-01), 13th Congress of the European College of Neuropsychopharmacology;Munich, Germany; September 09-13, 2000, pages S319, XP001009548, ISSN: 0924-977X
REINSTEIN MICHAEL J ET AL: "Effect of clozapine-quetiapine combination therapy on weight and glycaemic control: Preliminary findings.", CLINICAL DRUG INVESTIGATION, vol. 18, no. 2, August 1999 (1999-08-01), pages 99 - 104, XP001009552, ISSN: 1173-2563
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