Title:
METHOD OF TREATMENT OF DISSECTED LYMPH NODE AND/OR VESSEL
Document Type and Number:
WIPO Patent Application WO/2015/126917
Kind Code:
A3
Abstract:
Methods are provided that include applying to a surgical field in the patient following a lymphadenectomy or other procedure in which a lymph node or lymphatic vessel is dissected, a bioresorbable and biocompatible material in an amount effective to control oozing of lymphatic fluid. The material may be a hydrophilic polysaccharide material which, in contact with tissues in the surgical field, produces a gelled matrix that adheres to and forms a mechanical barrier with tissues in the surgical field to control oozing of lymphatic fluid. The hydrophilic polysaccharide material may include a modified starch such as a cross-linked carboxymethyl polysaccharide.
Inventors:
LANG DAVID (US)
Application Number:
PCT/US2015/016342
Publication Date:
October 22, 2015
Filing Date:
February 18, 2015
Export Citation:
Assignee:
CRYOLIFE INC (US)
International Classes:
A61K31/738; A61K31/715; A61L24/08; A61P41/00
Other References:
MATTHIAS WALDERT ET AL: "Floseal Reduces the Incidence of Lymphoceles After Lymphadenectomies in Laparoscopic and Robot-Assisted Extraperitoneal Radical Prostatectomy", JOURNAL OF ENDOUROLOGY, vol. 25, no. 6, June 2011 (2011-06-01), pages 969 - 973, XP055198569, ISSN: 0892-7790, DOI: 10.1089/end.2010.0635
STAFYLA V ET AL: "Effect of collagen powder on lymphorrhea after modified radical mastectomy. A randomized controlled trial", EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, vol. 32, no. 2, 2011, pages 185 - 187, XP009185074, ISSN: 0392-2936
GILLY F N ET AL: "Prevention of lymphorrhea by means of fibrin glue after axillary lymphadenectomy in breast cancer: Prospective randomized trial", EUROPEAN SURGICAL RESEARCH, vol. 30, no. 6, November 1998 (1998-11-01), pages 439 - 443, XP009185076, ISSN: 0014-312X
"The Next Generation Hemostat", May 2011 (2011-05-01), XP055198661, Retrieved from the Internet [retrieved on 20150626]
STAFYLA V ET AL: "Effect of collagen powder on lymphorrhea after modified radical mastectomy. A randomized controlled trial", EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, vol. 32, no. 2, 2011, pages 185 - 187, XP009185074, ISSN: 0392-2936
GILLY F N ET AL: "Prevention of lymphorrhea by means of fibrin glue after axillary lymphadenectomy in breast cancer: Prospective randomized trial", EUROPEAN SURGICAL RESEARCH, vol. 30, no. 6, November 1998 (1998-11-01), pages 439 - 443, XP009185076, ISSN: 0014-312X
"The Next Generation Hemostat", May 2011 (2011-05-01), XP055198661, Retrieved from the Internet
Attorney, Agent or Firm:
KING, Kevin W. et al. (999 Peachtree Street N, Atlanta Georgia, US)
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