Methods of Preparing Imidazole-Based Bicyclic Compounds

Title:

Methods of Preparing Imidazole-Based Bicyclic Compounds

Document Type and Number:

WIPO Patent Application WO/2010/008734

Kind Code:

A3

Abstract:

Methods of preparing compounds of formula I are disclosed:

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Inventors:

CHEN JASON GUOHUA (CN)
HU WEIFENG (CN)
LIU RENMAO (CN)
LU YUELIE (CN)
WU WENXUE (US)
YANG XIAOGEN (CN)

Application Number:

PCT/US2009/047495

Publication Date:

March 11, 2010

Filing Date:

June 16, 2009

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Assignee:

LEXICON PHARMACEUTICALS INC (US)
CHEN JASON GUOHUA (CN)
HU WEIFENG (CN)
LIU RENMAO (CN)
LU YUELIE (CN)
WU WENXUE (US)
YANG XIAOGEN (CN)

International Classes:

C07D261/04; A61K31/42; C07D413/04

Domestic Patent References:

WO2008109314A1	2008-09-12
WO2007002458A2	2007-01-04
WO1984003441A1	1984-09-13

Other References:

HALWEG K M ET AL: "A CONVENIENT SYNTHESIS OF 2-ACETYL-4(5)-(1(R),2(S),4-TETRAHYDROXYBUTY L)-IMIDAZOLE", JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, EASTON.; US, vol. 50, no. 7, 1 January 1985 (1985-01-01), pages 1134 - 1136, XP002446300, ISSN: 0022-3263
SWEENY J G ET AL: "Synthesis of 2-acetyl-4-(1,2,3,4-tetrahydroxybutyl)imidazole", JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, EASTON.; US, vol. 50, no. 7, 1 January 1985 (1985-01-01), pages 1133 - 1134, XP002487552, ISSN: 0022-3263

Attorney, Agent or Firm:

BACHRACH, Max (INC.8800 Technology Forest Plac, The Woodlands TX, US)

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