Title:
METHODS FOR THE ADMINISTRATION OF CERTAIN VMAT2 INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2018/140095
Kind Code:
A3
Abstract:
Provided are methods of administering a vesicular monoamine transport 2 (VMAT2) inhibitor chosen from valbenazine and (+)-α-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol, or a pharmaceutically acceptable salt and/or isotopic variant thereof, to a patient in need thereof wherein the patient is also being administered a strong cytochrome P450 2D6 (CYP2D6) inhibitor.
Inventors:
O'BRIEN CHRISTOPHER (US)
Application Number:
PCT/US2017/055965
Publication Date:
November 29, 2018
Filing Date:
October 10, 2017
Export Citation:
Assignee:
OBRIEN CHRISTOPHER F (US)
International Classes:
C07D455/06; A61K31/473
Domestic Patent References:
| WO2015077521A1 | 2015-05-28 | |||
| WO2016210180A2 | 2016-12-29 |
Foreign References:
| US20080167337A1 | 2008-07-10 | |||
| US20080108645A1 | 2008-05-08 |
Attorney, Agent or Firm:
STEVENS, Lauren, L. (US)
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