Title:
METHODS FOR AMELIORATION OF IMMUNODEFICIENCY VIRUS INDUCED NEURODEGENERATION BY COVERING NITRIC OXIDE OR SUPEROXIDE CONCENTRATION
Document Type and Number:
WIPO Patent Application WO1995014465
Kind Code:
A3
Inventors:
DAWSON VALINA L
DAWSON TED M
UHL GEORGE R
SNYDER SOLOMON H
DAWSON TED M
UHL GEORGE R
SNYDER SOLOMON H
Application Number:
PCT/US1994/013457
Publication Date:
August 17, 1995
Filing Date:
November 22, 1994
Export Citation:
Assignee:
UNIV JOHNS HOPKINS (US)
US OF AMERICA NATIONAL INST O (US)
US OF AMERICA NATIONAL INST O (US)
International Classes:
A61K31/00; A61K31/18; A61K31/195; A61K31/22; A61K31/415; A61K31/54; A61K38/13; (IPC1-7): A61K31/22; A61K31/18; A61K31/195; A61K31/415; A61K31/54; A61K31/71
Foreign References:
| US5266594A | 1993-11-30 |
Other References:
DAWSON VL ET AL: "mediated by nitric oxide in primary cortical cultures.", PROC NATL ACAD SCI U S A (UNITED STATES), APR 15 1993, VOL. 90, NO. 8, PAGE(S) 3256-9,
V.L. DAWSON ET AL. 'NITRIC OXIDE MEDIATES COMPONENTS OF NMDA AND GP120 NEUROTOXICITIES IN PRIMARY STRIATAL CULTURES', 22ND ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE, ANAHEIM, CALIFORNIA, USA, OCTOBER 25-30, 1992.;& SOC NEUROSCI ABSTR,, VOL. 18, NO. 1-2, PAGE(S) 756, 1992.
MORGAN MJ ET AL: "Possible roles for nitric oxide in AIDS and associated pathology", MED HYPOTHESES (ENGLAND), JUL 1992, VOL. 38, NO. 3, PAGE(S) 189-93,
MOLLACE V ET AL: "HIV gp120 glycoprotein stimulates the inducible isoform of no synthase in human cultured astrocytoma cells.", BIOCHEM BIOPHYS RES COMMUN (UNITED STATES), JUL 15 1993, VOL. 194, NO. 1, PAGE(S) 439-45,
V.L. DAWSON ET AL. 'NITRIC OXIDE MEDIATES COMPONENTS OF NMDA AND GP120 NEUROTOXICITIES IN PRIMARY STRIATAL CULTURES', 22ND ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE, ANAHEIM, CALIFORNIA, USA, OCTOBER 25-30, 1992.;& SOC NEUROSCI ABSTR,, VOL. 18, NO. 1-2, PAGE(S) 756, 1992.
MORGAN MJ ET AL: "Possible roles for nitric oxide in AIDS and associated pathology", MED HYPOTHESES (ENGLAND), JUL 1992, VOL. 38, NO. 3, PAGE(S) 189-93,
MOLLACE V ET AL: "HIV gp120 glycoprotein stimulates the inducible isoform of no synthase in human cultured astrocytoma cells.", BIOCHEM BIOPHYS RES COMMUN (UNITED STATES), JUL 15 1993, VOL. 194, NO. 1, PAGE(S) 439-45,
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