Title:
METHODS OF AMPLIFYING WHOLE GENOME OF A SINGLE CELL
Document Type and Number:
WIPO Patent Application WO/2012/166425
Kind Code:
A3
Abstract:
Methods and compositions for amplifying the whole genome of a single cell are provided.
Inventors:
XIE XIAOLIANG SUNNEY (US)
ZONG CHENGHANG (US)
LU SIJIA (US)
ZONG CHENGHANG (US)
LU SIJIA (US)
Application Number:
PCT/US2012/038930
Publication Date:
May 08, 2014
Filing Date:
May 22, 2012
Export Citation:
Assignee:
HARVARD COLLEGE (US)
XIE XIAOLIANG SUNNEY (US)
ZONG CHENGHANG (US)
LU SIJIA (US)
XIE XIAOLIANG SUNNEY (US)
ZONG CHENGHANG (US)
LU SIJIA (US)
International Classes:
C12Q1/68
Foreign References:
| US20030108870A1 | 2003-06-12 | |||
| US20030100006A1 | 2003-05-29 | |||
| US20040209298A1 | 2004-10-21 | |||
| US20090018031A1 | 2009-01-15 | |||
| US20050019793A1 | 2005-01-27 | |||
| US20090291475A1 | 2009-11-26 |
Other References:
DATABASE GENBANK [online] 1 May 2006 (2006-05-01), GOETZ ET AL.: "Oncorhynchus mykiss regulator of G-protein signalling 14 mRNA, complete cds.", XP003032883, Database accession no. AY606041
PELAK ET AL.: "The characterization of twenty sequenced human genomes.", PLOS GENET., vol. 6, no. 9, 9 September 2010 (2010-09-09), pages 1 - 10, XP055140362
REGIER ET AL.: "Increased yield of PCR product from degenerate primers with nondegenerate, nonhomologous 5' tails.", BIOTECHNIQUES., vol. 38, no. 1, January 2005 (2005-01-01), pages 34 - 38, XP055140363
FAN ET AL.: "Whole-genome molecular haplotyping of single cells.", NAT. BIOTECHNOL., vol. 29, no. 1, 2011, pages 51 - 57, XP055026438
PELAK ET AL.: "The characterization of twenty sequenced human genomes.", PLOS GENET., vol. 6, no. 9, 9 September 2010 (2010-09-09), pages 1 - 10, XP055140362
REGIER ET AL.: "Increased yield of PCR product from degenerate primers with nondegenerate, nonhomologous 5' tails.", BIOTECHNIQUES., vol. 38, no. 1, January 2005 (2005-01-01), pages 34 - 38, XP055140363
FAN ET AL.: "Whole-genome molecular haplotyping of single cells.", NAT. BIOTECHNOL., vol. 29, no. 1, 2011, pages 51 - 57, XP055026438
Attorney, Agent or Firm:
IWANICKI, John, P. (Suite 1800Boston, Massachusetts, US)
Download PDF:
Previous Patent: LIFT-OFF PROCESSING FOR FORMATION OF ISOLATION REGIONS IN LASER DIODE STRUCTURES
Next Patent: HOME AND TRAVEL BIDET
Next Patent: HOME AND TRAVEL BIDET