Title:
METHODS AND COMPOSITIONS FOR CALICIVIRIDAE
Document Type and Number:
WIPO Patent Application WO/2015/175526
Kind Code:
A3
Abstract:
Disclosed herein are methods and compositions for calicivirus. Methods comprise in vitro cell culture systems used for diagnosis, identification, attenuation and other uses. Compositions comprise in vitro cell culture systems for calicivirus.
Inventors:
KARST STEPHANIE (US)
JONES MELISSA K (US)
JONES MELISSA K (US)
Application Number:
PCT/US2015/030361
Publication Date:
February 11, 2016
Filing Date:
May 12, 2015
Export Citation:
Assignee:
UNIV FLORIDA (US)
International Classes:
C12N7/02; C12M3/00; C12N5/0781
Foreign References:
| US20050255480A1 | 2005-11-17 | |||
| DE102008028406A1 | 2009-12-31 |
Other References:
GONZALEZ-HERNANDEZ, MB ET AL.: "Murine Norovirus Transcytosis across an In Vitro Polarized Murine Intestinal Epithelial Monolayer Is Mediated by M-Like Cells.", J VIROL., vol. 87, no. 23, 18 September 2013 (2013-09-18), pages 12685 - 12693
MIURA ET AL.: "Histo-Blood Group Antigen-Like Substances Of Human Enteric Bacteria As Specific Adsorbents For Human Noroviruses.", J VIROL., vol. 87, no. 17, 26 June 2013 (2013-06-26), pages 9441 - 9451
WOBUS, CE ET AL.: "Replication of Norovirus in Cell Culture Reveals a Tropism for Dendritic Cells and Macrophages.", PLOS BIOL., vol. 2, no. 12, December 2004 (2004-12-01), pages 2076 - 2084
MUMPHREY, SM ET AL.: "Murine Norovirus 1 Infection is Associated With Histopathological Changes In Immunocompetent Hosts, But Clinical Disease Is Prevented By STAT1-Dependent Interferon Responses.", J VIROL., vol. 81, no. 7, April 2007 (2007-04-01), pages 3251 - 3263
KARST, SM ET AL.: "Advances In Norovirus Biology.", CELL HOST MICROBE., vol. 15, no. 6, 11 June 2014 (2014-06-11), pages 668 - 680, XP029033078, DOI: doi:10.1016/j.chom.2014.05.015
JONES, MK ET AL.: "Enteric Bacteria Promote Human And Mouse Norovirus Infection Of B Cells.", SCIENCE, vol. 346, no. 6210, 7 November 2014 (2014-11-07), pages 755 - 759
KARST, SM ET AL.: "A Working Model Of How Noroviruses Infect The Intestine.", PLOS PATHOG., vol. 11, no. 2, 27 February 2015 (2015-02-27), pages e1004626
MIURA ET AL.: "Histo-Blood Group Antigen-Like Substances Of Human Enteric Bacteria As Specific Adsorbents For Human Noroviruses.", J VIROL., vol. 87, no. 17, 26 June 2013 (2013-06-26), pages 9441 - 9451
WOBUS, CE ET AL.: "Replication of Norovirus in Cell Culture Reveals a Tropism for Dendritic Cells and Macrophages.", PLOS BIOL., vol. 2, no. 12, December 2004 (2004-12-01), pages 2076 - 2084
MUMPHREY, SM ET AL.: "Murine Norovirus 1 Infection is Associated With Histopathological Changes In Immunocompetent Hosts, But Clinical Disease Is Prevented By STAT1-Dependent Interferon Responses.", J VIROL., vol. 81, no. 7, April 2007 (2007-04-01), pages 3251 - 3263
KARST, SM ET AL.: "Advances In Norovirus Biology.", CELL HOST MICROBE., vol. 15, no. 6, 11 June 2014 (2014-06-11), pages 668 - 680, XP029033078, DOI: doi:10.1016/j.chom.2014.05.015
JONES, MK ET AL.: "Enteric Bacteria Promote Human And Mouse Norovirus Infection Of B Cells.", SCIENCE, vol. 346, no. 6210, 7 November 2014 (2014-11-07), pages 755 - 759
KARST, SM ET AL.: "A Working Model Of How Noroviruses Infect The Intestine.", PLOS PATHOG., vol. 11, no. 2, 27 February 2015 (2015-02-27), pages e1004626
Attorney, Agent or Firm:
EISENSCHENK, Frank, C. et al. (Lloyd & EisenschenkP.O. Box 14295, Gainesville FL, US)
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