Title:
METHODS AND COMPOSITIONS FOR CELL-BASED IMMUNOTHERAPIES
Document Type and Number:
WIPO Patent Application WO/2023/143475
Kind Code:
A1
Abstract:
Provided are methods of generating an immune cell, such as an engineered immune cell. In an aspect, provided is an in vitro method of generating stem cell-derived mesodermal cells. The method can comprise contacting a population of stem cells with a composition comprising an activator of Wnt/β-catenin signaling pathway (activator). The activator can be sufficient to transform the population of stem cells into a population of mesodermal cells.
Inventors:
YANG LUHAN (CN)
GAO YANGBIN (CN)
ZHAO JUANJUAN (CN)
YUE YANAN (CN)
YANG YANG (CN)
WANG XINGYUE (CN)
ZHU TIANTIAN (CN)
GAO YANGBIN (CN)
ZHAO JUANJUAN (CN)
YUE YANAN (CN)
YANG YANG (CN)
WANG XINGYUE (CN)
ZHU TIANTIAN (CN)
Application Number:
PCT/CN2023/073482
Publication Date:
August 03, 2023
Filing Date:
January 27, 2023
Export Citation:
Assignee:
HANGZHOU QIHAN BIOTECHNOLOGY CO LTD (CN)
International Classes:
C12N5/0783; A61K35/17; C12N5/0789
Domestic Patent References:
| WO2021032851A1 | 2021-02-25 | |||
| WO2021113744A1 | 2021-06-10 |
Foreign References:
| US20220025330A1 | 2022-01-27 | |||
| US20160143949A1 | 2016-05-26 | |||
| CN106459918A | 2017-02-22 |
Other References:
WEN-JUN YANG, PING HU: "Study on mesodermal cell lineages", CHINESE BULLETIN OF LIFE SCIENCES, vol. 28, no. 8, 24 August 2016 (2016-08-24), pages 849 - 855, XP093080941, DOI: 10.13376/j.cbls/2016112
Attorney, Agent or Firm:
AFD CHINA INTELLECTUAL PROPERTY LAW OFFICE (CN)
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