Title:
METHODS AND COMPOSITIONS FOR INFERRING EYE COLOR AND HAIR COLOR
Document Type and Number:
WIPO Patent Application WO2005079331
Kind Code:
A3
Abstract:
Methods for inferring eye color or eye shade of an individual from a nucleic acid sample of the individual by detecting the nucleotide occurrence of an eye color related single nucleotide polymorphism (SNP) as set forth in SEQ ID NOS:1 to 7 and, optionally,, SEQ NOS:8 to 10 and/or SEQ ID NOS:26 to 48, are provided. Also provided are methods for inferring hair color or hair shade of an individual from a nucleic acid sample of the individual by detecting the nucleotide occurrence of a hair color related SNP as set forth in SEQ ID NOS:11 to 25. Methods for inferring eye color/shade andVor hair color/shade of an individual from a protein sample of the individual by detecting an amino acid residue encoded by the nucleotide occurrence of an eye color related SNP or a hair color related SNP, respectively, also are provided. In addition, compositions, including oligonucleotides and antibodies, useful for practicing such methods are provided, as are kits for performing the methods.
Inventors:
FRUDAKIS TONY N (US)
Application Number:
PCT/US2005/004513
Publication Date:
September 14, 2006
Filing Date:
February 11, 2005
Export Citation:
Assignee:
DNAPRINT GENOMICS INC (US)
FRUDAKIS TONY N (US)
FRUDAKIS TONY N (US)
International Classes:
C07H21/04; C12Q1/68
Other References:
FRUDAKIS ET AL.: "Sequences associated with human Iris Pigmitation", GENETICS, vol. 165, December 2003 (2003-12-01), pages 2071 - 2083, XP008040049
STURM ET AL.: "Eye colour: portals into pigmentation genes and ancestry", TRENDS IN GENETICS, vol. 20, no. 8, August 2004 (2004-08-01), pages 327 - 332, XP004521546
STURM ET AL.: "Eye colour: portals into pigmentation genes and ancestry", TRENDS IN GENETICS, vol. 20, no. 8, August 2004 (2004-08-01), pages 327 - 332, XP004521546
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