Title:
METHODS AND COMPOSITIONS FOR REDUCING C-REACTIVE PROTEIN
Document Type and Number:
WIPO Patent Application WO2006014864
Kind Code:
A3
Abstract:
The present invention provides methods for the treatment and/or amelioration of inflammation in a subject, including humans, by administering to a subject a therapeutically effective amount of a biologically active mixture of high purity, high molecular weight straight chain primary aliphatic alcohols (referred to collectively herein as policosanol). Also included are methods of reducing levels of C-reactive protein in a subject, comprising administering to a subject a therapeutically effective amount of policosanol.
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Inventors:
BERLIN ROGER (US)
Application Number:
PCT/US2005/026294
Publication Date:
March 30, 2006
Filing Date:
July 21, 2005
Export Citation:
Assignee:
WYETH CORP (US)
BERLIN ROGER (US)
BERLIN ROGER (US)
International Classes:
A61K31/045; A61P9/00; A61P11/00; A61P13/12; A61P21/00; A61P29/00
Foreign References:
| US20030096876A1 | 2003-05-22 | |||
| EP0654262A1 | 1995-05-24 | |||
| US4714791A | 1987-12-22 | |||
| EP0561745A2 | 1993-09-22 |
Other References:
DATABASE WPI Section Ch Week 198901, Derwent World Patents Index; Class B04, AN 1989-004241, XP002351586
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1991, KABIR Y ET AL: "BIOCHEMICAL EFFECT OF OCTACOSANOL ON VOLUNTARY EXERCISE IN RATS", XP002351583, Database accession no. PREV199192139356
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; January 2003 (2003-01-01), KIM HYUNJUNG ET AL: "Octacosanol supplementation increases running endurance time and improves biochemical parameters after exhaustion in trained rats.", XP002351584, Database accession no. PREV200400128767
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1991, KABIR Y ET AL: "BIOCHEMICAL EFFECT OF OCTACOSANOL ON VOLUNTARY EXERCISE IN RATS", XP002351583, Database accession no. PREV199192139356
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; January 2003 (2003-01-01), KIM HYUNJUNG ET AL: "Octacosanol supplementation increases running endurance time and improves biochemical parameters after exhaustion in trained rats.", XP002351584, Database accession no. PREV200400128767
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