Title:
METHODS AND COMPOSITIONS RELATED TO NUCLEIC ACID-BASED FLUORESCENT NANOCLUSTER PROBES
Document Type and Number:
WIPO Patent Application WO/2023/133411
Kind Code:
A3
Abstract:
Disclosed are compositions and methods for detecting nucleic acid, or detecting the presence or absence of a nuclease. Specifically, disclosed herein are nucleic acid-metal nanocluster probes, which comprise a nucleic acid probe with metal nanoclusters associated therewith. These nucleic acid-metal nanocluster probes can be used to detect a variety of cleavage events, and can also be used to detect hybridization to the probe.
Inventors:
YEH HSIN-CHIH (US)
HONG SOONWOO (US)
CHEN YUAN-I (US)
KUO YU-AN (US)
NGUYEN TRUNG DUC (US)
HONG SOONWOO (US)
CHEN YUAN-I (US)
KUO YU-AN (US)
NGUYEN TRUNG DUC (US)
Application Number:
PCT/US2023/060100
Publication Date:
August 10, 2023
Filing Date:
January 04, 2023
Export Citation:
Assignee:
UNIV TEXAS (US)
International Classes:
C12N15/11; C12Q1/6818; C12N9/22; C12Q1/6816
Foreign References:
| US20170037455A1 | 2017-02-09 | |||
| US20200299768A1 | 2020-09-24 |
Attorney, Agent or Firm:
CLEVELAND, Janell T. et al. (US)
Download PDF: