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Title:
METHODS AND COMPOSITIONS FOR VACCINATION COMPRISING NUCLEIC ACID AND/OR POLYPEPTIDE SEQUENCES OF THE GENUS BORRELIA
Document Type and Number:
WIPO Patent Application WO2004103269
Kind Code:
A3
Abstract:
The invention relates to antigens and nucleic acids encoding such antigens obtainable by screening a Borrelia genome, in particular an B. burgdorferi genome. In more specific aspects, the invention relates to methods of isolating such antigens and nucleic acids and to methods of using such isolated antigens for producing immune responses. The ability of an antigen to produce an immune response may be employed in vaccination or antibody preparation techniques.

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Inventors:
BOARD OF REGENTS THE UNIVERSIT (US)
SYKES KATHRYN F (US)
HALE KATHERINE S (US)
JOHNSTON STEPHEN A (US)
Application Number:
PCT/US2003/033056
Publication Date:
December 29, 2005
Filing Date:
October 17, 2003
Export Citation:
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Assignee:
MACROGENICS INC (US)
BOARD OF REGENTS THE UNIVERSIT (US)
SYKES KATHRYN F (US)
HALE KATHERINE S (US)
JOHNSTON STEPHEN A (US)
International Classes:
A61K39/00; A61K39/02; A61K39/38; A61K48/00; A61K49/00; C07H21/02; C07H21/04; C07K1/00; C07K14/00; C07K14/195; C12Q1/00; C12Q1/68; A61K; (IPC1-7): A61K49/00; A61K39/00; A61K39/38; C07H21/02; C07H21/04; C07K1/00; C07K14/00; C12Q1/00
Foreign References:
US5582829A1996-12-10
US5688512A1997-11-18
US6083722A2000-07-04
US6183986B12001-02-06
US6113914A2000-09-05
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