65251/C766

1 METHODS FOR CREATING OR IDENTIFYING COMPOUNDS THAT BIND

TUMOR NECROSIS FACTOR ALPHA

CROSS-REFERENCE TO RELATED APPLIC ATION(S)

^■ * [0001] This application claims priority to and the benefit of U.S. Provisional Application Serial No. 61/168,133, filed April 9, 2009, and titled "Crystal Structure of Poxvirus Tumor Necrosis Factor-alpha (TNFα)-Binding Protein 2L in Complex with TNFα, Useful for the Design and Development of Anti-Inflammatory Pharmaceuticals," the entire content of which

10 is incorporated herein by reference.

INCORPORATION BY REFERENCE

[0002] The material in the text file titled "65251SequenceListing", created April 9, 2010, 15 and being 2700 bytes, is herein incorporated by reference in its entirety.

FIELD

[0003] The present invention relates to methods of creating and/or identifying thereapeutic candidate compounds expected to have useful immonomodulatory and/or anti-

20 inflammatory properties. In particular, the methods make use of a crystal structure of a

Yatapoxvirus 2L polypeptide bound to human TNFα to provide guidance as to desirable characteristics of the therapeutic candidate compounds.

²⁵ BACKGROUND

[0004] Tumor necrosis factor (TNF) secreted primarily by macrophages and monocytes, is a potent mediator cytokine of inflammation and the immune response to various pathogens (Aggarwal, BB 2003, Nat. Rev. Immunol. 3:745-756; Ware, C.F., 2005, Annu. Rev. Immunol.

30 23:787-819). The proinflammatory cytokine tumor necrosis factor α (TNFα) is the prototype member of the TNF superfamily that forms trimers, and is expressed as a membrane-bound 26-kDa protein and a soluble 17-kDa protein, both of which are biologically active. TNFα is a major target for pharmaceutical intervention in a number of autoimmune diseases including

- _r rheumatoid arthritis, septic shock, ulcerative colitis, Crohn's disease and other syndromes (Mocellin et al, 2005, Cytokine Growth Ractor Rev., 16:35-53).

[0005] Large DNA viruses such as poxviruses, which replicate exclusively within the cytoplasm of infected cells, encode diverse immunomodulatory proteins to modulate, avoid, 65251/C766

or diminish multiple antiviral responses mediated by hosts (Seet et al., 2003, Annu. Rev.

Immunol., 21 :377-423; Alcami, 2003, Nat. Rev. Immunol. 3:36-50; Nazarian et al, 2006, Future Virol, 1 :123-132). Given the broad immune effects of TNFα, viruses have developed potent TNFα inhibitors — some derived from host TNF receptors (Rahman, 2006, PLoS Pathog, 2 e4). The Yatapoxvirus genus of poxviruses includes Tanapox virus (TPV), Yaba monkey tumor virus (YMTV), and Yaba-like disease virus (YLDV) (Knight et al, 1989, Virology, 172: 1 16-124). Several members of this genus of poxviruses have been found to encode an hTNFα inhibitor, designated as 2L, that bears little homology to endogenous hTNF receptors.

[0006] The 2L poxvirus protein was originally isolated as a potential human therapeutic, with the rationale that agents developed over millennia in the struggle between viruses and the vertebrate immune system may be particularly well tuned for modulation of the immune response. However, since even the existing anti-TNFα drugs exhibit limitations in efficacy for treating disease, there is a need for improved human anti-TNFα therapeutics based on the 2L poxvirus protein and methods for obtaining such therapeutics.

SUMMARY

[0007] According to an aspect of the invention, there is provided a method of creating a therapeutic candidate compound comprising: providing a secreted form of a 2L polypeptide of SEQ ID No. 1, SEQ ID No. 2, or SEQ ID No. 3; modifying at least one amino acid of the 2L polypeptide at a position other than the 2L interface amino acids HIS58, GLU99, GLYlOl, PHE104, LYS125, GLY157, TYR160, MET161, GLY162, LEU165, LEU168, GLN171, LYS175, GLU225, VAL229, ASN230, GLY231, ARG232, or GLU289 for SEQ ID No.'s 1-2 or HIS57, GLUlOO, GLY102, PHE105, LYS126, GLY157, TYR161, ALA162, GLY163, LEU166, PHE169, GLN172, LYS176, GLU226, VAL230, ASN231, GLY232, ARG233, or GLU290 for SEQ ID No. 3, to form a candidate compound; and, purifying the candidate compound.

[0008] According to another aspect of the invention, there is provided a method of creating a therapeutic candidate compound comprising: providing a sequence of a 2L polypeptide comprising SEQ ID No. 1, SEQ ID No. 2, or SEQ ID No. 3; modifying at least one amino acid of the sequence of the 2L polypeptide at a position other than HIS58, GLU99, GLYlOl, PHE104, LYS125, GLY157, TYR160, METl 61, GLY162, LEU165, LEU168, GLN171, LYS175, GLU225, VAL229, ASN230, GLY231, ARG232, or GLU289 for SEQ 65251/C766

ID No.'s 1-2 or at a position other than HIS57, GLUlOO, GLY102, PHE105, LYS126, GLY157, TYRl 61, ALA162, GLY163, LEU166, PHE169, GLN172, LYS176, GLU226, VAL230, ASN231, GLY232, ARG233, or GLU290 for SEQ ID No. 3, to form a sequence of a candidate compound; expressing the sequence of the candidate compound from a host cell to create a secreted form of the candidate compound; and, purifying the candidate compound. [0009] These methods may further comprise verifying that the candidate compound binds to human TNFα with a binding affinity Kd of from about 40 picomoles to about 440 picomoles. [0010] According to yet another aspect of the invention, there is provided a method of creating a therapeutic candidate compound comprising: providing a secreted form of a 2L polypeptide of SEQ ID No. 1, SEQ ID No. 2, or SEQ ID No. 3; modifying at least one amino acid of the 2L polypeptide at a position selected from the group consisting of HIS58, GLU99, GLYlOl, PHE104, LYS125, GLY157, TYR160, METl 61, GLY162, LEU165, LEU168, GLN171, LYS175, GLU225, VAL229, ASN230, GLY231, ARG232, and GLU289 for SEQ ID No.'s 1-2 or at a position selected from the group consisting of HIS57, GLUlOO, GLY102, PHE105, LYS126, GLY157, TYR161, ALA162, GLY163, LEU166, PHE169,

GLNl 72, LYS176, GLU226, VAL230, ASN231, GLY232, ARG233, and GLU290 for SEQ

ID No. 3, to form a candidate compound; and, purifying the candidate compound.

[0011] According to still another aspect of the invention, there is provided a method of creating a therapeutic candidate compound comprising: providing a sequence of a 2L polypeptide comprising SEQ ID No. 1, SEQ ID No. 2, or SEQ ID No. 3; modifying at least one amino acid of the sequence of the 2L polypeptide at a position selected from the group consisting of HIS58, GLU99, GLYlOl, PHE104, LYS125, GLY157, TYR160, MET161, GLY162, LEU165, LEU168, GLN171, LYS175, GLU225, VAL229, ASN230, GLY231, ARG232, and GLU289 for SEQ ID No.'s 1-2 or at a position selected from the group consisting of HIS57, GLUlOO, GLY102, PHE105, LYS126, GLY157, TYR161, ALA162, GLY163, LEU166, PHE169, GLN172, LYS176, GLU226, VAL230, ASN231, GLY232, ARG233, and GLU290 for SEQ ID No. 3, to form a sequence of a candidate compound; expressing the sequence of the candidate compound from a host cell to create a secreted form of the candidate compound; and, purifying the candidate compound.

[0012] These methods may further comprise verifying that the candidate compound binds to human TNFα with a binding affinity K _d less than that of the 2L polypeptide. [0013] These methods may further comprise an N-terminal signal sequence. 65251/C766

i [0014] These methods may be provided wherein the immature sequence is according to

SEQ ID No. 15, SEQ ID No. 16, or SEQ ID NO. 17.

[0015] The foregoing methods may further comprise confirming in vitro that the candidate compound suppresses signaling via the TNFα cascade. The methods may further comprise confirming in vitro that the candidate compound competitively inhibits human TNFRl or human TNFR2 from binding to human TNFα. The modification of the at least one amino acid may be selected from the group consisting of substitution, addition and deletion. [0016] According to even another aspect of the present invention, there is provided a

10 method for determining whether or not a test compound is a therapeutic candidate compound for use in treating a TNFα mediated disease or condition in humans, the method comprising: providing the test compound or an electronic representation of the test compound; determining whether the test compound or electronic representation of the test compound binds to at least TNFα interface amino acids TYR87, ARG31, ARG32, ASN30, SER86, ARG82, GLU127, ASN34, VAL91, ALA33, VAL91, GLN21, ARG44, GLU42, LEU37, LEU43, VAL41 and GLN27 of hTNFα, or competitively inhibits binding of hTNFRl or hTNFR2 to the TNFα interface amino acids, to within a specified confidence interval; for test compounds that bind to the TNFα interface amino acids or competitively inhibit binding of

20 human TNFRl or human TNFR2 to the TNFα interface amino acids, confirming in vitro that the test compound suppresses signaling via the TNFα cascade, thereby rendering it a therapeutic candidate compound.

[0017] hi any of the foregoing methods, the method may further comprise verifying that

25 the candidate compound binds to human TNFα with a shape complementarity index of from 0.64 to 0.78. The methods may further comprise verifying that the candidate compound, upon binding to human TNFα, imparts a change in conformation of human TNFα at GLN21, ALA22, GLU23, GLY24, GLN25, ARG31, ARG32, ALA33, ASN34, ALA35, PHE144, ALA145, GLU146, SER147, and GLY148. The methods may further comprise verifying that the modification reduces immunogenicity of the candidate compound as compared with the 2L polypeptide of SEQ ID No.'s 1, 2 or 3. The methods may further comprise verifying that the modification alters the circulating half life of the candidate compound as compared with the 2L polypeptide of SEQ ID No.'s 1, 2 or 3. The methods may further comprise

^■ " verifying that the candidate compound binds to human TNFα over a surface area of at least 2000 A ² . 65251/C766

[0018] According to yet still another aspect of the invention, there is provided a therapeutic candidate compound obtained according to any of the foregoing methods. [0019] According to yet even another aspect of the invention, there is provided a method of treating a TNFα mediated disease or condition in humans comprising administering a therapeutic candidate compound obtained according to any of the foregoing methods in an amount and for a time sufficient to achieve a therapeutic effect. This can be alternatively described as use of a therapeutic candidate compound according to any of the foregoing methods in an amount and for a time sufficient to achieve a therapeutic effect in treating a TNFα mediated disease or condition in humans. It is contemplated to use the therapeutic candidate compound in the manufacture of a medicament for treating a TNFα mediated disease or condition or in a pharmaceutical composition comprising the purified therapeutic candidate compound with a pharmaceutically acceptable diluent formulated for administration to a patient suffering from or at risk of developing a TNFα mediated disease or condition.

[0020] A purified nucleic acid molecule that encodes a polypeptide comprising the sequence of the candidate compound is also provided as part of this invention, along with any purified nucleic acid molecule that hybridizes under high stringency conditions to the aforementioned nucleic acid molecule. A vector comprising the nucleic acid molecule and a host cell comprising the vector are also provided.

[0021] According to yet even still another aspect of the invention, there is provided a crystal of the secreted form of Yaba-like disease virus 2L protein bound to human TNFα. The Yaba-like disease virus 2L protein may comprise an amino acid sequence according to SEQ ID No. 1. The crystal may have a three-dimensional structure as defined by the atomic coordinates of Table 4 with a root mean square deviation of 1.0 A for each atomic coordinate.

BRIEF DESCRIPTION OF THE DRAWINGS

[0022] These and other features and advantages of the present invention will be better understood by reference to the following detailed description when considered in conjunction with the attached drawings, in which:

[0023] Fig. IA is a ribbon diagram of the 2L-TNFa complex looking down the 3-fold symmetry axis;

[0024] Fig. IB is a ribbon diagram of the 2L-TNFa complex with the 3 -fold axis vertical; 65251/C766

[0025] Fig. 1C shows a surface representation of TNF α from the complex structure with the 2L binding site in the darkened region;

[0026] Fig. 2A shows a πbbon diagram of 2L with the α3 domain insertion;

[0027] Fig. 2B shows stereo Ca superposition of the al-a2 platforms of 2L with HLA-

A2 and FcRn,

[0028] Fig. 2C shows a surface representation of the 2L αl-α2 platform shown in the same orientation as Fig. 2B,

[0029] Fig. 2D shows a close-up of a πbbon diagram of the interface between the 2L αl- α2 platform and α3 domain with the interface amino acids labeled;

[0030] Fig 2E shows a stereo superposition of 2L and HLA- A2 with an arrow indicating displacement of the 2L α3 domain compared to the HLA- A2 α3 domain;

[0031] Fig 2F shows stereo representation of 2L with β2m showing N-linked glycosylation at Asn6;

[0032] Fig 3A shows surface representations of 2L (left) and the 2L-TNFa complex

(right);

[0033] Fig 3 B shows πbbon diagrams corresponding to the surface representations of Fig. 3A;

[0034] Fig 3 C shows stereo close-ups of the 2L-TNFa interface with the α3 domain insertion;

[0035] Fig. 4 shows a sequence alignment of mature poxvirus 2L proteins including

YLDV (Yaba-like disease virus); TPV (Tanapox virus); YMTV (Yaba monkey tumor virus),

Deerpox (Deerpox virus strain W-848-83; Swinepox (Swinepox open reading frame SPV003) with boxes highlighting the interface residues,

[0036] Fig. 5 shows a sequence alignment of mammalian TNFα proteins and human

TNFβ, and,

[0037] Fig. 6 shows a stereo superposition of 2L-bound TNFα and unbound TNFα.

DETAILED DESCRIPTION

[0038] Design and development of a therapeutic agent that binds TNFα while evading the immune system can be efficiently realized from the specific binding interface of the poxvirus 2L protein and TNFα. As shown herein, the Yaba-like disease virus (YLDV) 2L protein complexed to TNFα has been isolated and crystallized, and its crystal structure has 65251/C766

been determined and analyzed. The crystal structure data includes the three-dimensional molecular and atomic coordinates (Table 4) and computed modeling of the 2L-TNFa complex (Fig. 1A-1C). In addition to the disclosed crystal structure, the present invention also provides methods for identifying and designing novel 2L-based TNFα binding compounds that modulate TNFα activity.

[0039] U.S. Patents 7,585,507 and 6,894,155 to McFadden et al, are incorporated by reference herein in their entirety. These patents describe immune modulation of TNFα using full length (exclusive of signal sequence) 2L molecules. As described herein, a method is provided for designing candidate TNFα-binding compounds based on the specific 2L and TNFα residues found to interact at the 2L-TNFa interface.

[0040] Definitions [0041] Unless defined otherwise, all technical and scientific terms used herein have the meaning commonly understood by one of ordinary skill in the art relevant to the invention. The definitions below supplement those in the art and are directed to the embodiments described in the current application.

[0042] Immature YLDV, TPV and YMTV 2L proteins are represented by SEQ ID NOs. 15, 16 and 17, respectively. Mature untagged YLDV, TPV and YMTV 2L proteins are represented by SEQ ID NOs: 1, 2 and 3, respectively. [0043] As used herein, the "2L-TNFa interface" refers to the amino acid residues of the

2L protein that interact directly with TNFα, and the TNFα amino acid residues that interact directly with 2L. The interface residues are listed in Table 1. Direct interaction is defined by those residues that have at least 2% ASA (accessible surface area) and/or form a salt bridge or hydrogen bond. As used herein, the interface can refer to both the 2L and TNFα amino acids that interact with each other. [0044] The "2L interface" and the "2L interface residues" refer to the 2L amino acids that directly interact with TNFα. The 2L interface residues of YLDV 2L (SEQ ID NO: 1) and TPV 2L (SEQ ID NO: 2) include: HIS58, GLU99, GLYlOl, PHE104, LYS125, GLY157, TYRl 60, MET161 or ALA161, GLY162, LEU165, LEU168 or PHE168, GLN171, LYS175, GLU225, VAL229, ASN230, GLY231 , ARG232, and GLU289. The 2L interface residues of YMTV 2L (SEQ ID NO: 3) include: HIS57, GLUlOO, GLYl 02, PHE105, LYS126, GLY157, TYR161, ALA162, GLY163, LEU166, PHE169, GLN172, LYS176, GLU226, VAL230, ASN231, GLY232, ARG233, and GLUl 90. 65251/C766

_j [0045] The "TNFα interface" and the "TNFα interface residues" refer to the human

TNFα amino acids that directly interact with 2L. The TNFα interface residues include: TYR87, ARG31 , ARG32, ASN30, SER86, ARG82, GLU127, ASN34, VAL91 , ALA33, VAL91, GLN21, ARG44, GLU42, LEU37, LEU43, VAL41, and GLN27. [0046] "Polypeptide," "polypeptide fragment," "peptide," or "peptide fragment" means a chain of two or more amino acids, regardless of any post-translational modification (e.g., glycosylation, acetylation, or phosphorylation), constituting all or part of a naturally or non- naturally occurring polypeptide. A "protein" can be made up of one or more polypeptides or

10 one or more peptides.

[0047] "Post-translational modification" means any change to a polypeptide or polypeptide fragment during or after synthesis. Post-translational modifications can be produced naturally (such as during synthesis within a cell) or generated artificially (such as

, _< - by recombinant or chemical means). One example of a post-translational modification occurs during secretion from a cell, in which an N-terminal signal sequence is cleaved from an immature intracellular protein to yield a extracellular mature, processed, or secreted form of the protein. The amino acids that make up the N-terminal signal sequence of a protein can be readily determined by persons skilled in the art from the immature protein sequence using,

20 for example, software tools such as SignalP (as originally described by Henrik Nielsen, Jacob

Engelbrecht, Søren Brunak and Gunnar von Heijne in "Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites.", Protein Engineering, 10:1- 6, 1997, and available for use at www.cbs.dtu.dk/Services/SignalP.)

25 [0048] By "candidate compound" or "compound" is meant a molecule, be it naturally- occurring or artificially-derived, that is assayed for its ability to bind TNFα by employing one of the assay methods described herein. Candidate compounds may include, for example, peptides, polypeptides, aptamers, Fc fusion proteins, antibodies, synthesized organic

T _Q molecules, naturally occurring organic molecules, nucleic acid molecules, and biologically active fragments thereof.

[0049] A "mutation" includes a deletion, a conserved amino acid change and/or non- conserved amino acid change, or an addition of an amino acid.

[0050] By "analog" is meant any substitution, addition, or deletion in the amino acid

35 sequence of a 2L-derived TNFα-binding candidate compound that exhibits properties that are at least 50%, preferably at least 75%, more preferably at least 90%, and most preferably at least 95% of the immunomodulatory properties of the poxvirus 2L protein from which it is 65251/C766

derived. Analogs can differ from the naturally occurring 2L protein by amino acid sequence differences, by amino acid sequence or post-translational modifications, or by both. Modifications include in vivo and in vitro chemical derivatization of polypeptides, e.g., acetylation, carboxylation, phosphorylation, or glycosylation. Such modifications may occur during polypeptide synthesis or processing or following treatment with isolated modifying enzymes. Analogs can also differ from the naturally occurring poxvirus 2L polypeptide by alterations in primary sequence. These include genetic variants, both natural and induced (for example, resulting from random mutagenesis by irradiation or exposure to agents such as ethanemethylsulfate, or by site-specific mutagenesis as described in Sambrook, Fritsch and Maniatis, Molecular Cloning: A Laboratory Manual (2d ed.), CSH Press, 1989, hereby incorporated by reference; or Ausubel et al., Current Protocols in Molecular Biology, John Wiley & Sons, New York, 1994, hereby incorporated by reference). Also included are polypeptide molecules that contain residue substitutions for L-amino acids, e.g., D-amino acids or non-naturally occurring synthetic amino acids. Fragments and analogs can be generated using standard techniques, for example, solid phase peptide synthesis or polymerase chain reaction (PCR).

[0051] "2L-derived TNFα-binding candidate nucleic acid molecule" means a nucleic acid molecule, such as a genomic DNA, cDNA, or RNA (e.g., mRNA) molecule that encodes a

2L-derived TNFα-binding candidate polypeptide having the desired characteristics or biological activities of a poxvirus 2L polypeptide as described herein.

[0052] "Immune function" or "immunoreactivity" refers to the ability of the immune system or immune system factors in an in vitro assay, to respond to a foreign antigen as measured by standard assays. "Modulate" or "modulating" means the induction of a quantitative change, either by decrease or increase, in the response of a target cell, sample, or organism, as a result of an interaction with a TNFα protein or nucleic acid molecule or candidate compound. The increase or decrease is by at least 10%, preferably by at least 20%, more preferably by at least 50%, still more preferably by at least 75%, yet more preferably by at least 95% and most preferably by at least 100% relative to an untreated control organism, sample, or molecule.

[0053] "Immunomodulation" or "immunomodulatory" refers to an alteration in the overall immunoreactivity of the immune system in a mammal, or alteration in the response of a cell, relative to an untreated control of the same type, upon treatment with an agent, such as a polypeptide or nucleic acid molecule of the present invention, or fragments and analogs 65251/C766

thereof Immunomodulation can be assayed using immune cells, for example, B cells, T cells, antigen-presenting cells, or any other cell that is involved in immune function Immunomodulation can also be assayed by determining expression and/or activity of immune-related genes and proteins, or immune-related compounds, such as cytokines, cytokine receptors, immunoglobulins, etc

[0054] "Immunosuppression" refers to a decrease in the overall immunoreactivity of the immune system upon administration of an immunomodulator in comparison to the immunoreactivity of an immune system that has not been contacted with the particular immunomodulator "Immunostimulation" refers to an increase in the overall immunoreactivity of the immune system upon administration of an immunomodulator in compaπson to the immunoreactivity of an immune system that has not been contacted with the particular immunomodulator "Decreasing T cell stimulation" means loweπng the level of T cell stimulation as measured by, for example, a chromium release assay "Decreasing inflammation" means decreasing the number of inflammatory cells (leukocytes, for example eosinophils) in the target tissue by, preferably, two-fold By "cell proliferation" is meant the growth or reproduction of similar cells By "apoptosis" is meant the process of cell death where a dying cell displays a set of well-characterized biochemical hallmarks which include cytolemmal blebbmg, cell soma shrinkage, chromatin condensation, and DNA laddeπng [0055] "Immunomodulator" refers to an agent that induces an immunomodulatory effect or alteration (i e , immunosuppression, immunostimulation, etc ) as measured, for example, by an alteration of virulence in mutated viruses or a vaπety of immunoassays well known in the art (for example, chemotaxis assays as descπbed herein) For example, in the present invention, an immunomodulator may elicit an altered level of immune function, such that the alteration in the level of immune function identifies a viral 2L polypeptide An "antiinflammatory" agent is an immunomodulatory agent capable of decreasing the overall inflammation or immune function upon administration to an individual F

Identification of 2L-TNFa Interface

[0056] From the crystal structure and analysis thereof, as descπbed throughout and specifically detailed in Example I and Table 4, the ammo acid residues participating in the

2L-TNFa interface of the 2L-TNFa complex are identified as shown in Table 1 65251/C766

[0057] Table 1. Interactions between 2L and TNFα % ASA (accessible surface area) = percent of the total interface ASA contributed by each residue Residues contributing less that 2% of interface ASA were excluded unless they are involved in hydrogen bonds or salt bπdges (indicated by asteπsks)

Table 1

2L TNPα

2L Residue Location %ASA Residue (subunit) Location

HIS58* αl helix 4 TYR87 (B) D-E loop

GLU99* β5 strand 6 ARG31 (A) A-A' loop

GLU99* β5 strand ARG32 (A) A-A' loop

GLYlOl β5-β6 loop 2 ARG31 (A) A-A' loop

PHEl04 β6 strand 6 ASN30 (A) A-A' loop

PHE104 β6 strand ARG31 (A) A-A' loop

LYS125 β7-β8 loop 5 SER86 (B) D-E loop

GLYl57 α2 helix 3 SER86 (B) D-E loop

GLYl57 cc2 helix TYR87 (B) D-E loop

TYRl60 α2 helix 9 ARG82 (B) D strand

TYRl60 α.2 helix SER86 (B) D-E loop

TYRl60 α2 helix GLUl27 (B) F-G loop

MET161 α2 helix 8 ASN34 (A) A-A' loop

MET161 α2 helix ARG82 (B) D strand

MET161 α2 helix VAL91 (B) E strand

GLYl62 α2 helix 2 TYR87 (B) D-E loop

LEU165 α2 helix 3 ALA33 (A) A-A' loop

LEUl65 α2 helix VAL91 (B) E strand

LEUl68 α2 helix 3 ARG32 (A) A-A' loop

GLNl71 α2 helix 4 GLN21 (A) A-A' loop

LYS175 α2 helix 4 GLN21 (A) A-A' loop

GLU225* α3 insertion 2 ARG44 (A) B' strand

VAL229 α3 insertion 5 GLU42 (A) B' strand

VAL229 α3 insertion ARG44 (A) B' strand

ASN230 α3 insertion 7 ASN30 (A) A-A' loop

ASN230 α3 insertion LEU37 (A) A' strand

ASN230 α3 insertion LEU43 (A) B' strand

GLY231 α3 insertion 6 LEU37 (A) A' strand

GLY231 α3 insertion VAL41 (A) B' strand

GLY231 α3 insertion GLU42 (A) B' strand

ARG232* α3 insertion 5 GLU42 (A) B' strand

ARG232 α3 insertion ARG44 (A) B' strand

GLU289 F-G loop 4 GLN27 (A) A-A' strand

GLU289* F-G loop ARG31 (A) A-A' strand

[0058] The analysis and modeling of the atomic coordinates (Table 4) of the 2L-TNFa crystal structure reveal that 2L binds to TNFα using a large and highly complementary interface as represented in Figs. 2A, 2B, 2C) The high (picomolar) affinity between 2L and 65251/C766

TNFα (Brunetti et al , 2003, PNAS, 100:4831-4836) is rationalized by the properties of the interaction. For example, the TNFα binding site on 2L spans a long (nearly 40 A) distance, and the total buried surface area at the 2L-TNFa interface (2060 A ² , of which 1030 A ² are contributed by 2L, and 710 A ² and 320 A ² are contributed by adjacent TNFα subunits in the trimer) is considerably larger than the areas of typical protem-protein recognition interfaces (1560-1700 A ² ) (Jones er a/., 1996. iW.4S; 93:13-20).

[0059] The interface also exhibits a high degree of complementarity as assessed by the shape complementarity index, Sc, an index that vanes from 0 (not complementary) to 1 (a perfect fit) (Lawrence, 1993, JMoI Biol 234: 946-950). The S _c value for the 2L-TNFa interface is 0.72, indicating a more complementary interface than typical antibody-antigen interfaces with S _c values of 0.64-0.68 (Lawrence, 1993, J MoI Biol. 234: 946-950). By comparison, the TNFRl/TNFβ interface has a lower shape complementarity index (Sc = 0.64), but buries a similar surface area (2120 A ² , with 1090 A ² from TNFRl and 530 A ² and 510 A ² from adjacent TNFβ subunits).

[0060] Despite shaπng only -13% sequence identity with human class I MHC heavy chains and lacking the β2m light chain, the 2L protein adopts a class I MHC-like fold including an αl-α2 superdomain, comprising an anti-parallel β-sheet topped by two α- helices, and an α3 domain with an immunoglobulin constant region β-sandwich fold (Fig. 2A). Disulfide bonds are found in the expected positions for class I MHC molecules and homologs: linking the α2 domain helix to the β-sheet floor of the αl-α2 platform, and joining the two β-sheets in the α3 domain. In addition, there is a disulfide bond near the C- termmus joining residues separated by only three residues.

[0061] In a compaπson with structures of classical class I MHC molecules and other class I MHC homologs, including CDl, HFE, FcRn, ZAG, MIC-A, M10.5, T-22, RAE-I and viral class I homologs (UL18, ml44 and ml57), the αl-α2 superdomain of 2L was most similar to that of a classical MHC protein, HLA- A2 with a root mean square deviation (RMSD) of 1.4 A for 104 Ca atoms) (Table 2). However, in common with most class I homologs (HFE, FcRn, MIC-A, T-22, RAE-I, and the viral class I homologs ml 44 and ml 57), 2L does not contain a noticeable groove between its αl and α2 domain helices (groove surface area of 60 A ² ) and no unexplained electron density was observed in this region. In this regard, 2L is more similar to HFE and FcRn (groove surface areas of 415 A ² and 235 A ² , respectively) (Lebron et al, 1998, Cell, 93 : 111-123), which do not present 65251/C766

endogenous peptides, than it is to classical peptide-binding class I MHC molecules (groove surface areas of -760 A ² ), the peptide-binding viral homo log ULl 8 (groove surface area of 900 A ² ), or the lipid-presenting CDldl protein (groove surface area of 1440 A ² ) (Yang, 20QS, PNAS, 105: 10059-10100; Lebron et al., 1998, Cell, 93: 111-123 ; Olson et al, 2005, PLoS Biol, 3: e257).

[0062] Table 2. Root mean square deviations (RMSD) for superpositions of the αl-α2 platform of 2L with platforms of MHC and MHC-like molecules.

Protein RMSD Cαs aliened PDB code

HLA-A2 1.43 A 104 atoms 2CLR

M10.5 1.45 A 105 atoms 1ZS8

ULl 8 1.56 A 105 atoms 3D2U

ZAG 1.69 A 107 atoms IZAG

T22 1.70 A 96 atoms 1C16

FcRn 1.73 A 123 atoms IEXU

CDldl 1.75 A 113 atoms ICDl

HFE 1.77 A 102 atoms 1A6Z ml44 1.81 A 90 atoms 1U58 ml57 1.83 A 80 atoms 2NYK

MIC-A 1.85 A 103 atoms IHYR

RAE-I 1.91 A 91 atoms UFM

Data Analysis of Crystal Structure

[0063] The structure of the 2L-bound TNFα trimer resembles its counterparts in structures of unliganded TNFα (Eck and Sprang, 1989, J Biol Chem, 264:17595-17605) and

TNFRl-bound TNFβ (Banner et al, 1993, Cell, 73: 431-445)(Fig. 6) (RMSD of 0.91 A for

148 Ca atoms for the TNFα-TNFα comparison, and 0.95 A for 134 Ca atoms for the TNFβ- TNFα comparison), consisting of protomers with two antiparallel β-sheets with a jellyroll folding topology. The relatively modest conformational changes in the 2L-bound TNFα structure include movement of the A-A' loop (residues 31-35) located at the 2L binding site. This different conformation permits two salt bridge interactions: 2L Glu99 with TNFα Arg31 and Arg32, and 2L Glu289 with TNFα Arg31 (Fig. 3C). The corresponding region of TNFβ, residues 48-52, also exhibits changes in mainchain and sidechain torsion angles upon binding TNFRl (Banner et al, 1993). Smaller changes were also observed in the other binding site loops of TNFα, including residues 144-148 and 21-25 (Fig. 6). In one embodiment, a TNF α- binding candidate compound confers a conformational change in residues 31-35 (ARG31, 65251/C766

ARG32, ALA33, ASN34, ALA35), residues 21-25 (GLN21, ALA22, GLU23, GLY24, GLN25), and residues 144-148 (PHE144, ALA145, GLU146, SER147, GLY148) of TNFα (SEQ ID NO: 14).

[0064] 2L binds to TNFα using residues from all three of its domains to interact with the region surrounding the shallow groove between adjacent TNFα subunits, burying loops D-E and A-A', which are also critical for TNFα binding to TNFRl and TNFR2 (Mukai et ah, 2009, JMoI. Biol. 385: 1221-1229) and TNFβ binding to TNFRl (Banner et al, 1993, Cell, 73:431-445) (Figs. 1, 3). A major component of the 2L-TNFa interface involves TNFα D-E loop residues 86-87 from one subunit and A-A' loop residues 30-34 from the neighboring subunit interacting with 2L α2 domain helix residues 157-175. For example, the sidechain of TNFα residue Tyr87 in the D-E loop, a critical residue for binding both TNFRs (Mukai et ah, 2009), contacts the kink in the 2L α2 domain helix and forms a hydrogen bond with His58 from the αl domain helix. Some features of the TNF binding site for 2L and host TNFRs differ: G-H loop residues Aspl43 and Alal45 and residues in the E-F loop, which are part of the TNFα binding site for TNFRl (Loetscher et ah, 1993, J Biol Chem, 268: 26350-26357) do not contact 2L, and TNFα strand B', which interacts with the insertion in the 2L α3 domain, is not part of TNF's binding site with host receptors.

[0065] Consistent with the observation that poxvirus 2L proteins show varying degrees of specificity for binding TNFα from different species (Rahman et ah, 2006, J Biol Chem, 281 : 22517-22526, which is incorporated herein by reference), the TNFα binding site on 2L is less conserved than the rest of the protein: 26% (5 of 19) of the binding site residues are conserved in 2L proteins from four or more poxviruses, compared with an overall conservation of 42% (125 of 299 residues) (Fig. 4). Sequence diversity at the binding site is likely related to adaptation of poxviruses to the TNFα of their host species. Similarly, variability in classical class I MHC molecules primarily maps to a different location, the peptide-binding groove, resulting in distinct allele-specific peptide-binding preferences (Madden, \995, Annu Rev Immunol, 13:587-622). Accordingly, in one embodiment, a TNFα-binding candidate compound is a 2L-derived polypeptide wherein the starting 2L protein is YLDV 2L (SEQ ID NO: 1) or TPV 2L (SEQ ID NO: 2), and the candidate compound has at least one amino acid modified that is not one of the 2L interface residues. Upon modification, the residue position of the interface amino acids may be altered without necessarily imparting a change to the structure of the 2L interface or its binding to the TNFα 65251/C766

I interface residues. Therefore, the positions of the amino acids at the interface need not necessarily correspond to the positions prior to modification, although it may be desirable for them to do so.

[0066] In another embodiment, a TNFα-binding candidate compound is a 2L-derived polypeptide wherein the starting 2L protein is YMTV 2L (SEQ ID NO: 3). YMTV 2L binds monkey TNFα with a binding affinity (Ka) of 230 picomoles, and binds human TNFα with a K _d of 440 picomoles (Rahman et al, 2006). The binding affinity of YMTV 2L derived TNFα-binding candidate compounds for human TNFα may therefore be reduced as

10 compared with YLDV 2L or TPV 2L derived compounds, which can be advantageous in the treatment of certain immunomodulatory diseases.

[0067] Unlike naturally occurring host TNFRs, 2L does not bind to TNFβ or other TNF family members (Brunetti et al. 2003, PNAS, 100:4831-4836). To better understand this

15 desirable specificity for binding TNFα, TNFβ was superimposed on the 2L-TNFa structure (Fig. 6). Although mainchain atom steric clashes were not apparent, the specificity of 2L for TNFα may be related to the complementarity of acidic residues (2L Glu99 and Asp289) to basic residues in the TNFα A'-A' ' loop (Arg31 and Arg32) (Fig. 2C), which are not present

2 _Q in TNFβ (Fig. 5). In addition, binding of TNFβ may be prevented by different positions of the TNF D-E loops (residues 85-89 in TNFα; 106-110 in TNFβ), which differ by -2.5 A, as measured between the Ca atoms of analogous residues (TNFα Tyr87 and TNFβ Tyrl08). It would therefore be desirable to preserve these 2L residues and/or the relative positions thereof with reference to TNFa during any modification of the starting 2L sequence to form a candidate compound.

Candidate TNFa-Bindins Compound

[0068] In one aspect of the invention, a method for designing a therapeutic TNFα binding

30 candidate is provided. In one embodiment, the method comprises first providing a 2L protein having an amino acid sequence of SEQ ID NOs: 1, 2, or 3. The method then comprises modifying the 2L protein without modification to any of the 2L interface residues, which are: HIS58, GLU99, GLYlOl , PHEl 04, LYS125, GLY157, TYR160, MET161 or ALA161, 35 GLY162, LEU165, LEU168 or PHE168, GLN171, LYS175, GLU225, VAL229, ASN230, GLY231, ARG 232, and GLU289, wherein MET 161 and LEU168 correspond to SEQ ID 65251/C766

NOs: 1-2 (YLDV and TPV 2L) and ALA161 and PHE168 correspond to SEQ ID NO: 3

(YMTV 2L).

[0069] In another embodiment of the method, similar, or equivalent amino acids may be substituted for those disclosed above at the 2L-TNFa interface. Conservative substitutions include substitutions within the following groups: glycine, alanine, valine, isoleucine, and leucine; aspartic acid, glutamic acid, asparagine, and glutamine; serine and threonine; lysine and arginine; and phenylalanine and tyrosine. [00701 hi the foregoing aspect of the invention, it is desirable that the candidate either binds to the TNFα interface residues participating in the 2L-TNFa interface or prevents binding of a TNFR to the TNFα interface residues participating in the 2L-TNFa interface. The TNFR may be TNFRl . The TNFα-binding candidate may include the amino acid residues shown in Table 1, having at least 2% accessible surface area (ASA) or contributing to hydrogen bonds or salt bridges.

[0071] In another aspect of the invention, a method for designing a TNFα-binding candidate is provided wherein the method comprises providing a candidate that has a shape complementarity index, (S ₀ ) value that is from 0.64 to 0.78. It should be noted that the S ₀ for TNFRl/TNFβ is 0.64, and S _c for typical antibody-antigen interfaces is from 0.64 to 0.68 (Lawrence, 1993, J MoI Biol 234: 946-950). The candidate compound may have an S _c value that is from 0.64 to 0.72 or about 0.72. The candidate compound may have an S _c value that is from 0.65 to 0.78, from 0.66 to 0.78, from 0.67 to 0.78, from 0.68 to 0.78, from 0.69 to 0.78, from 0.70 to 0.78, from 0.71 to 0.78, from 0.72 to 0.78, from 0.73 to 0.78, from 0.74 to 0.78, from 0.75 to 0.78, from 0.76 to 0.78, or from 0.77 to 0.78.

[0072] In one aspect of the invention, a method for designing a candidate TNFα-binding compound is provided wherein the candidate binds to TNFα amino acid residues TYR87, ARG31, ARG32, ASN30, SER86, ARG82, GLU127, ASN34, VAL91, ALA33, VAL91, GLN21, ARG44, GLU42, LEU37, LEU43, VAL41, and GLN27.

[0073] In one embodiment, a method for designing a candidate TNFα-binding compound is provided wherein the candidate amino acid sequence is not a 2L protein, but includes the atomic coordinates of the 2L interface of Table 1 and Table 4 within an acceptable 1.0 Angstrom root mean square deviation (RMSD) (Baber et al, 2009, J. Chem. Inf. Model., 49 (8): 1889-1900). 65251/C766

[0074] In one embodiment, a method for designing a candidate TNFa-binding compound is provided wherein starting with a 2L protein sequence (e.g. SEQ ID NOs: 1, 2 or 3), the candidate amino acid sequence is provided to a webserver that predicts potential MHC class I epitopes from a peptide sequence (e.g. the SYFPEITHI web server). Of the amino acids predicted to be epitopes, those which participate in the 2L-TNFa interface, or which form part of the scaffold proximal and/or crucial to the interface, can be modified, but modification may not be desired given their critical role for 2L binding to TNFα. Accordingly, modification of the 2L polypeptide may at least initially be guided by modifying those amino acids that are predicted to fall within an MHC I epitope and are not in the 2L interface (Example 1). With respect to epitopes, mutation of one residue can eliminate the epitope (Griffith et al., 1987, J of Immunol., 138: 4480-4483; Smahel et al., 2008, Cancer Immunol, Immunotherapy, 57: 823-831). Similarly, in another embodiment, a 2L peptide sequence is provided to a webserver that predicts MHC II and/or B-cell epitopes.

Expression/Purification of 2L-Derived TNFα Binding Candidates

[0075] TNFα binding candidate DNA constructs are made as disclosed (Rahman et al.,

2009 Virology 386:462-468, which is incorporated herein by reference). A DNA plasmid, for example, plasmid pcDNA-2L, contains the complete YLDV 2L (SEQ ID NO: 4), TPV 2L (SEQ ID NO: 5) or YMTV 2L (SEQ ID NO: 6) open reading frame. The desired mutated sequences are PCR amplified with specific oligonucleotide primers using a DNA polymerase {e.g. Pfu DNA polymerase, Stratagene, La Jolla, CA), and the pcDNA 2L as template. [0076] The TNFα candidate plasmids are transferred into an expression vector for transfection and expression in an expression system. For example, the pcDNA plasmid is transferred into pFastBacl plasmid, (Invitrogen, Carlsbad, CA) and recombinant baculoviruses are produced using the Bac-to-Bac expression system following the manufacturer protocols. In brief, the plasmids are transformed into competent DHlOBac bacteria where a transposition event generated the corresponding recombinant bacmids. The purified bacmid DNA are transfected into Sf21 insect cells and the recombinant baculoviruses are harvested from the cell culture supernatant 3-5 days after transfection. 65251/C766

I Screening for Compounds That Bind to TNFα Interface Residues

[0077] The 2L- TNFα crystal structure as disclosed herein is useful in methods of creating or identifying candidate compounds using a structure-based approach. As is known in the art, screens to identify agonist and antagonist molecules for TNFα can be used. Accordingly, using the methods as disclosed, for example, in KoIb et al., 2009, PNAS, 106: 6843-6848 and Casey et al, 2009, J Chem Inf Model, 49: 2708-2717, a test compound that binds to TNFα at the TNFα interface residues or prevents binding of hTNFRl and/or hTNFR2 to the TNFα interface residues can be identified as a therapeutic candidate compound. The test compound can optionally confer a desired conformational change an/or have a desired binding affinity. The test compound may be a small molecule, polypeptide, protein, aptamer, antibody, fusion protein or nucleic acid comprised of naturally occurring or artificial constituents. In one embodiment, a test compound is screened for its ability to bind

15 the TNFα interface residues TYR87, ARG31, ARG32, ASN30, SER86, ARG82, GLU127, ASN34, VAL91, ALA33, VAL91, GLN21, ARG44, GLU42, LEU37, LEU43, VAL41, and GLN27.

^ _n Modification of TNFα Candidate Compound

[0078] In one embodiment, a modification is made to a 2L-derived TNFα-binding candidate comprising modifying one or more of any residue of a 2L protein (SEQ ID NOs: 1-3) that is not in the 2L interface. The modification may cause the candidate to have increased or decreased TNFα binding activity compared to the original 2L protein, wherein 25 the reduction or increase in the activity is a direct result of the modification to the amino acid residues not in the 2L interface.

[0079] In one embodiment, a candidate compound designed in accordance with the present inventionmay be made by any means known in the art. For example, PCR can be

30 used to generate a polynucleotide comprising codons that result in a mutation in one or more of the corresponding non-interface 2L amino acid residues. Commercial kits are also available for producing mutants, such as QuikChange™ (Stratagene, La Jolla, CA). In addition, site directed mutagenesis may be employed, as well as chemical synthesis. The

35 skilled artisan is well versed in the methods available for producing the polynucleotides and polypeptides of the present invention. 65251/C766

Affinity Binding of Candidate Compounds

[0080] The affinity of the candidate compound to TNFα is measured using one of several methods known in the art. For example, (Rahman et al, 2006, J Biol Chem 281 :22517- 22526) recombinant candidate proteins are immobilized at low densities of- 500 RU on CM5 chips and varying concentrations of TNF alpha protein is applied to the chips. Following an association period of 120 seconds, running buffer HBS-EP is injected to monitor the dissociation phase of binding. In one embodiment, the candidate binding compound has an affinity to TNFα of from about 43 picomoles (pm) to 440 pm (Rahman et al. 2006, J Biol Chem, 281: 22517-22526). hi one embodiment, the candidate binding compound of the present invention has a binding affinity to TNFα of from about 40 pm to about 445 pm. Alternatively, the candidate TNFα-binding compound has a Kd value that is from 40 pm to 440 pm, from 40 pm to 430 pm, from 40 pm to 420 pm, from 40 pm to 410 pm, from 40 pm to 400 pm, from 40 pm to 390 pm, from 40pm to 380 pm, from 40 pm to 370 pm, from 40 pm to 360 pm, from 40 pm to 350 pm, from 40 pm to 340 pm, from 40 pm to 330 pm, from 40 pm to 320 pm, from 40 pm to 310 pm, from 40 pm to 300 pm, from 40 pm to 290 pm, from 40 pm to 280 pm, from 40 pm to 270 pm, from 40 pm to 260 pm, from 40 pm to 250 pm, from 40 pm to 240 pm, from 40 pm to 230 pm, from 40 pm to 220 pm, from

40 pm to 210 pm, from 40 pm to 200 pm, from 40 pm to 190 pm, from 40 pm to 180 pm, from 40 pm to 170 pm, from 40 pm to 160 pm, from 40 pm to 150 pm, from 40 pm to 140 pm, from 40 pm to 130 pm, from 40 pm to 120 pm, from 40 pm to 110 pm, from 40 pm to 100 pm, from 40 pm to 90 pm, from 40 pm to 80 pm, from 40 pm to 70 pm, from 40 pm to 60

[0081] In an alternative embodiment, the candidate binding compound of the present invention decreases the binding affinity to TNFα. For example, a method for decreasing affinity to TNFα compared to any of the full length 2L proteins may be desired in order to attenuate binding. As such, in one embodiment, a method for a 2L-derived candidate compound is provided comprising modifying one or more amino acid residues of a 2L protein within the 2L interface residues. In another embodiment, a 2L-derived candidate compound that has decreased binding to TNFα compared to 2L, has a modification in one more amino acid residues of the 2L interface in addition to one or more amino acid residues that do not participate in the 2L interface. 65251/C766

Competitive Binding

[0082] To determine the binding preference for a candidate TNFα binding compound with respect to known TNFα binding proteins, e.g. 2L, TNFR2, etc, a competitive binding assay is used. Competitive/inhibition binding assays are known in the art. A preferred

ELISA method for determining candidate TNFα binding compounds and their affinity by competitive inhibition is disclosed in Brunetti et al. 2003, PNAS, 100:4831-4836. In one embodiment, the candidate TNFα-binding compound of the present invention competitively inhibits the binding of TNFα to TNFR2. In one embodiment, the competitive binding of the candidate compound inhibits the binding of TNFα to TNFRl at least 30%, preferably at least 50%, more preferably at least 75%, and most preferably at least 95% compared to 2L polypeptide.

Therapeutic Methods Employing TNFα Candidate Binding Compound

[0083] The invention includes methods of treating or preventing immunological disorders by using immunomodulatory agents. 2L-derived TNFα binding polypeptides identified in the present invention that exhibit anti-cytokine activity, anti-inflammatory activity, and/or exhibit a decrease in leukocyte chemotaxis activity are considered particularly useful in the invention; such polypeptides may be used, for example, as therapeutics to decrease the immunoreactivity in an individual with rheumatoid arthritis. Other immunological disorders that may be treated using an immunosuppressive agent, or an agent that reduces the immune function, include acute inflammation, allergic reactions, asthmatic reactions, inflammatory bowel diseases (i.e., Crohn's Disease and ulcerative colitis), transplant rejection, and restenosis. Alternatively, a polypeptide that enhances or induces apoptosis may be used in the treatment of tumors.

[0084] Treatment or prevention of diseases resulting from an immunomodulatory disorder is accomplished, for example, by modulating the function of an immunoregulatory protein by delivering a 2L-derived TNFα candidate protein to the appropriate cells. It is also possible to correct an immune defect by modifying the physiological pathway (e.g., a signal transduction pathway), in which the immunoregulatory protein participates, by delivering a TNFα candidate protein or nucleic acid molecule to the appropriate cells.

[0085] Direct administration of a recombinant TNFα protein, nucleic acid molecule, antibody, or compound, either to the site of a potential or actual disease-affected tissue (for example, by injection), or systemically for treatment of, for example, an autoimmune or 65251/C766

2 inflammatory disorder, can be performed accordingly to any conventional recombinant protein administration technique known m the art or described herein. The actual dosage depends on a number of factors known to those of ordinary skill in the art, including the size and health of the individual patient, but generally, between 0.1 mg and 100 mg inclusive are administered per day to an adult in any pharmaceutically-acceptable formulation. [0086] A TNFα immunomodulator, antiflammatory agent, or anticarcinogen may be administered with a pharmaceutically-acceptable diluent, earner, or excipient, at a pharmaceutically effective dose. Conventional pharmaceutical practice may be employed to

10 provide suitable formulations or compositions to administer TNFα candidate compounds to patients suffering from an immunomodulatory disorder. Any appropriate route of administration may be employed, for example, parenteral, intravenous, subcutaneous, intramuscular, intracranial, intraorbital, ophthalmic, intraventricular, intracapsular,

, _< - intraspinal, intracisternal, intrapentoneal, intranasal, aerosol, or oral administration.

Therapeutic formulations may be in the form of liquid solutions or suspensions; for oral administration, formulations may be in the form of tablets or capsules; and for intranasal formulations, in the form of powders, nasal drops, or aerosols.

[0087] Methods well known in the art for making formulations are found in, for example,

20

"Remington's Pharmaceutical Sciences, supra." Formulations for parenteral administration may, for example, contain excipients, steπle water, or saline, polyalkylene glycols such as polyethylene glycol, oils of vegetable origin, or hydrogenated napthalenes. Biocompatible, biodegradable lactide polymer, lactide/glycolide copolymer, or polyoxyethylene-

25 polyoxypropylene copolymers may be used to control the release of the compounds. Other potentially useful parenteral delivery systems for TNFα candidate immunomodulatory compounds include ethylene- vinyl acetate copolymer particles, osmotic pumps, implantable infusion systems, and liposomes. Formulations for inhalation may contain excipients, for

T _Q example, lactose, or may be aqueous solutions containing, for example, polyoxyethylene-9- lauryl ether, glycocholate and deoxycholate, or may be oily solutions for administration in the form of nasal drops, or as a gel.

Animal Models

2L-derived TNFα binding immunomodulators of this invention and other compounds found to be effective at the level of protein expression or activity are tested in animal models, for efficacy in treating, for example, autoimmune and inflammatory diseases and cancer. In 65251/C766

one embodiment, a method of testing a candidate TNFα-bindmg compound is provided, compπsing: selecting a candidate compound that binds to TNFα, assaying the compound for a disease in an animal model for the disease, and, determining if the compound decreases the disease in the animal model in compaπson to known compounds (i.e control inhibitors)— e.g

TNFα antibodies, as descπbed (U.S. 7,070,775) and etanercept, (Enbrel™) (U S 5,712,155)

[0088] Animal models for testing the immunomodulatory effects of candidate compounds are well known in the art. Therefore, the present invention refers to a selection of animal models that can be used to test the candidate compounds of the invention. Animal models proposed for use in the present invention to test candidate compounds for their efficacy in treating autoimmune and inflammatory disorders include, but are not limited to: Acute Inflammation: [0089] Animal models of acute inflammation are targeted for initial and rapid drug efficacy screening, and for their potential predicative value of outcomes in chronic inflammatory diseases. The following animal models can be used to test the candidate compounds of the present invention for their efficacy in treating acute inflammation: 1) carrageenm-induced inflammation model; 2) turpentine-induced inflammation model; 3) transgenic HLAB-27 inflammation model; and 4) ear-scratch model of inflammation

Rheumatoid Arthritis: Rat, Mouse, Rabbit

[0090] Efficacy in Rheumatoid Arthritis evaluated in: 1 ) various antigen-induced arthritis models in rabbit, rat, and mouse; and 2) in transgenic rheumatological models

[0091] The molecular and cellular mechanisms of action of the candidate compounds are evaluated by testing their efficacy in influencing key intracellular mechanisms that regulate degradative processes involved in joint disease Important molecular and cellular mechanisms that receive particular attention include signaling events regulating disease processes such as increased angiogenesis, synovial hyperplasia, and matrix metalloprotease expression. These processes have been implicated in cartilage degradation in arthritic diseases. [0092] 1 Collagen-induced Arthritis. Rat, Mouse, Rabbit

Autoimmune-mediated polyarthritis can be induced in certain strains of rodents (rat, mouse and rabbit) and non-human pπmates by immunizing them with native type II collagen The collagen-induced arthritis model is widely used and well characterized. Collagen-induced arthritis is mediated by susceptibility to autoantibodies which bind to a particular region of type II collagen. The mechanism of induction is linked to MHC-class II molecules but also depends on the species of type II collagen used for immunization 65251/C766

i [0093] 2. Ovalbumin-induced Arthritis; Rabbit

Candidate compounds are tested for efficacy in decreasing signs and symptoms of ovalbumin arthritis. Polyarthritis is induced in rabbits by immunizing them with Ovalbumin.

[0094] 3. Adjuvant-induced Arthritis: Rat, Mouse, Rabbit

Candidate compounds are tested for the efficacy in decreasing signs and symptoms of adjuvant-induced arthritis. Polyarthritis is induced in certain strains of rodents by immunizing them with Freud's Adjuvant.

[0095] 4. Streptococcal Cell Wall-induced Arthritis: Rat

10 Candidate compounds are tested for efficacy in decreasing signs and symptoms of streptococcal cell wall-induced arthritis. Chronic, erosive polyarthritis is induced by intraperitoneal injection of an aqueous suspension of cell wall fragments isolated from group A streptococci.

[0096] Transplant Rejection (Acute and Chronic)

Efficacy in transplant rejection is evaluated in various models of graft vascular disease (GVD). GVD is the most common cause of late graft failure in solid organ transplantation. GVD or graft atherosclerosis is characterized by plaque formation and fibrosis in small vessels. The development of graft vascular disease has been associated with acute allograft rejection, ischemia-reperfusion injury, and bacterial or viral infections. The common pathway of these postoperative insults results in perivascular inflammation which triggers migration of mesenchymal cells into the vessel wall, eventually resulting in occlusion or partial occlusion of the vessel lumen.

25 [0097] 1. Aortic Allograft Model: Rat, Rabbit, Monkey

Candidate compounds are tested for efficacy in reducing graft atherosclerosis and transplant rejection in a model of vascular injury after transplantation of aortic segments performed in certain strains of MHC mismatched rats, monkeys, and rabbits. [0098] 2. Tracheal Allograft Model: Rat, Rabbit, Monkey

Candidate compounds are tested for efficacy in reducing graft atherosclerosis and transplant rejection in a model of vascular injury after transplantation of tracheal segments performed in certain strains of MHC mismatched rats, rabbits, and monkeys. [0099] 3. Heterotopic Heart Transplant: Mouse, Rat, Monkey

^3J A heterotopic heart transplantation is performed in MHC mismatched animals. In this model, animals are treated with cyclosporine A for only the first 7 days after transplantation are 65251/C766

allowed to develop graft vascular disease, and are then analyzed after sacrifice at postoperative day 90.

[00100] 4. Orthotopic Kidney Transplant: Mouse, Rat, Monkey An orthotopic kidney transplantation is performed in MHC mismatched animals. In this model, animals receiving subtherapeutic doses of cyclosporine A for the first 10 days after transplantation are allowed to exhibit features of chronic renal allograft rejection in 70% of cases, and are then analyzed after sacrifice at postoperative day 90. [00101] 5. Orthotopic Lung Transplant: Rat, Monkey Candidate compounds are tested for effectiveness in delaying or reducing signs and symptoms of organ rejection after lung whole organ transplantation in rats and monkeys. [00102] 6. Reperfusion Injury: Rat

The immediate postoperative course in clinical lung transplantation is often severely impaired by delayed graft function as a result of ischemia and reperfusion injury. Preventive efficacy of drug candidates in ischemia-reperfusion injury is evaluated using a model of acute in vivo double lung transplantation in the rat (Hausen et al., Ann. Thorac. Surg. 61 :1714-9, 1996 incorporated herein by reference).

[00103] Restenosis

Candidate compounds are tested for efficacy in reducing atherosclerotic plaque deposition in a model of coronary restenosis after balloon angioplasty. Atherosclerotic plaque formation is critically involved in vascular occlusion and has been linked to excessive inflammatory and thrombotic response to arterial injury. [00104] Asthma: Rodent

The effectiveness of candidate compounds in reduction of signs and symptoms of asthma is evaluated in rodent models of antigen-induced experimental airways inflammation. The models include:

[00105] 1. Ovalbumin-induced Experimental Airways Inflammation: Rodent

Candidate compounds are tested for efficacy in reducing inflammatory cell components in the bronchoalveolar lavage of the lungs after aerosol challenge in ovalbumin-sensitized rodent models of experimental airways inflammation.

[00106] 2. Ovalbumin-induced Allergic Sensitization in Presence of GM-CSF Transgene

Expression: Mice

Candidate compounds are tested for efficacy in reducing inflammatory cell components in the 65251/C766

bronchoalveolar lavage of the lungs of mice after ovalbumin aerosol challenge in the context of local expression of GM-CSF (Staempfli et al., J. CHn. Invest., Vol. 102:9, 1704-1714). [00107] Inflammatory Bowel Disease (IBD): Mice and Rats

Drug candidates are evaluated for their potential therapeutic efficacy in ulcerative colitis or Crohn's disease utilizing various models of antigen-induced and genetically-mediated spontaneous chronic intestinal inflammation in mice and rats. Examples include: [00108] 1. Dextran Sulfate Sodium Induced IBD: Mice Chronic, irreversible clinical symptoms of IBD are induced by treating mice with an oral administration of dextran sulfate sodium.

[00109] 2. Gene Deletion and Transgenic Models for IBD: Rodent Compound efficacy will be tested in transgenic rodent lines which develop symptoms closely resembling the human elements of inflammatory bowel disease. Models include, the targeted deletion of the genes encoding IL-2, IL-10, TGF beta, T-cell receptor alpha/beta, keratin 8, Gi2 alpha. In addition, animals expressing transgenes for the human WA-B27 and HLA-B27 as well as a dominant negative construct which functionally blocks N-cadherin will be tested. [00110] Uveitis

Drug candidates will be evaluated for efficacy in various animal models of uveitis. Key models include both, experimental autoimmune uveitis and adoptively transferred experimental autoimmune uveitis. [00111] 1. Experimental Autoimmune Uveitis (EAU)

EAU is a T-cell mediated inflammatory eye disease that can be induced in several mammalian species by immunization with ocular-specific antigens (Gery et al., Invest. Opthalmol. Vis. Sci., 27: 1296-1300, 1986,. Sanui et al., J. Exp. Med., 169:1947-1989, incorporated herein by reference). This experimental disease is considered a model for a family of inflammatory eye diseases in humans and has been used to examine numerous modalities before their human testing.

[00112] 2. Adoptively Transferred Experimental Autoimmune Uveitis

Adoptively transferred EAU is induced through injection of lymphocytes presensitized against the retinal antigen are injected into naive syngenic recipients (McAllister et al., J.

Immunol, 138:1416-1420, 1987 incorporated herein by reference). 65251/C766

! EXAMPLES

1. Modified 2L Polypeptide

[00113] YLDV 2L amino acid sequence (SEQ ID NO: 1) was provided to the SYFPEITHI webserver. YLDV 2L residues 218-226 (ESEHFKGEY) are predicted to bind to MHC class I molecule HLA-A*01. The amino acids in positions 3 and 9 of this peptide fragment, E220 and Y226, respectively, are important to binding to HLA-A*01 (FaIk et al., 1994, Immunogenetics, 40: 238-241). Examining the 2L-TNF crystal structure (Table 1 and

10 Table 4), one can determine that changing TYR226 may be problematic since it appears to form part of a hydrophobic core stabilizing the 2L protein. On the other hand, GLU220 does not appear to have any structural role and does not contact TNFα. Thus one could predict that the mutant 2L protein E220S wherein a serine (SER) is substituted for the glutamic acid

^ (GLU), would be stable, bind strongly to TNF -alpha, and have one less potential epitope for HLA-A*01.

2. Crystal Structure of 2L-TNFa Complex

20 [00114] Materials and Methods for purification of complexed 2L-TNFa protein crystal. The gene for 2L was isolated by PCR from the Yaba-like disease virus (ATCC number VR- 937) using a forward primer 2LF (SEQ ID NO: 7):

CATGGATAAGTTACTATTATTTAGCAC and reverse primer 2LR (SEQ ID NO: 8): TCAGTCTTCTTCATCCTCTTCACCTTCC. A C-terminally His-tagged version of 2L lacking six C-terminal residues (residues 1-316 of the mature protein) (SEQ ID NO: 18) was amplified by PCR using a forward primer JYl 52 (forward primer, with kozaq sequence and BamHI site) (SEQ ID NO: 9): CGCGGATCCCCTATAAATATGGATAAGTTACTATTATTTAGC and the reverse in υ primer, JYl 54 (reverse primer stops at aa 332, with Xhol site) (SEQ ID NO: 10)

CCGCTCGAGACCTTCTCCTTCTTCTGTTTTTCTATATAG. This C-terminally His- tagged 2L protein was subcloned into a dicistronic baculovirus transfer vector, pAcUW31 (PharMingen) subcloned with the human β2m gene. His-tagged 2L and β2m (both included 35 native hydrophobic leader sequences) were expressed together in baculovirus-infected insect cells (Hi5 cells), hi the numbering system used herein for 2L, the first amino acid of the mature 2L chain is residue 1 ; a previous numbering system, which started at the initial 65251/C766

^ methionine of the signal peptide, refers to this residue as 17 (Brunetti et al, 2003, PNAS,

100: 4831-4836; Rahman et al, 2006, J Biol Chem, 281 :22517-22526; Rahman et al, 2009, Virology, 386: 462-468). 2L was purified by nickel-NTA and gel filtration chromatography as a monomer lacking detectable β2m. An N-terminally His-tagged form of human TNFα (residues 6-157, numbered as in PDB entry ITNF) (SEQ ID NO: 11) was amplified from an IMAGE TNFα cDNA clone using the TNF forward primer, (SEQ ID NO: 12) GACCATATGGGCAGCCATCATCATCATCATCACCGAACCCCGAGTGACAAGCCT G and TNR reverse primer, (SEQ ID NO: 13)

10 GACCTCGAGTCACAGGGCAATGATCCCAAAG was expressed in the E. CoIi cytoplasm using the expression vector pET23a (Novagen, EMD, Gibbstown, NJ), and soluble TNFα (SEQ ID NO: 14) was purified from bacterial lysates by nickel-NTA and gel filtration chromatography. i 5 [00115] Purified 2L and TNFα trimer were mixed at a 3 : 1 molar ratio and passed over a S200 16/60 gel filtration column in 20 mM Tris pH 7.5, 150 mM NaCl. The 2L-TNFa complex was isolated and then concentrated to 14 mg/ml and used to set up crystallization trials by hanging drop vapor diffusion. Crystals were obtained in 7-12% PEG 6K, sodium citrate pH 5.0-5.5, 0.2 M NaBr in monoclinic space group Fl _x (a = 101.7, b = 170.3, c =122.0, β = 92.04°) with two 3:1 2L:TNFα complexes per asymmetric unit. The crystal used for data collections had been soaked in 0.5 mM methylmercury chloride, but no heavy atoms were found in the refined structure.

[00116] Structure Analysis. Data were processed using HKL2000 (Otwinowski et al,

25

1997, Meth Enzymol, 276: 307). The structure was determined by molecular replacement using a TNFα (Eck and Sprang, 1989, J Biol Chem, 264: 17595-17605) search model followed by location of 2L molecules using the coordinates of the αl-α2 platform of ZAG (PDB code 1T7V) (Delker et al, 2004, J Struct Biol, 148: 205-213) in a real space search

30 (Sanchez et al, 1999, Science, 283: 1914-1919) (Table 3). After rigid-body refinement

McCoy et al, 2007, JAppl Cryst, 40: 658), rebuilding was done using the program O (Jones et al, 1997, Methods Enzymol, 277: 173) and 2F ₀ -F ₀ annealed omit maps, alternating with refinement using CNS (Brunger et al, 1998, Acta Crystallogr D Biol Crystallogr, 54: 905- _n c 921). Non-crystallographic symmetry (NCS) restraints (300 kcal/mol) and group B factor refinement were used during refinement. The final model consisted of six NCS-related sets of atoms: 2L residues 1-299, TNFα residues 6-157, 16 water molecules, and 42 atoms of carbohydrate (ordered carbohydrate attached to 2L residues Asn6, Asn52, and Asn83, but not 65251/C766

_j to Asnl97, the final potential N-linked glycosylation site in the 2L sequence). The following cysteine pairs were disulfide bonded: 2L 97-163 (difference Fourier maps indicated some radiation-induced breakage of this bond (Burmeister, 2000, Acta Crystallogr D Biol Crystallogr, 56: 328-341), 202-281, 295-299, and TNFα 69-101. 2L residues 300-316, its C- terminal His-tag, and the N-terminal His-tag of TNFα were disordered. [00117] For analysis of contacts and buried surface areas, the 2L αl-α2 platform was defined as residues 1-179 and the α3 domain was defined as residues 180-299. The CCP4 program AREAIMOL (CCP4, 1994, Acta Crystallogr D Biol Crystallogr, D50: 760-763) was

* " used to calculate buried surface areas using a 1.4 A probe. To identify interacting residues, a maximum distance of 4.0 A for van der Waals interactions was used. Shape complementarity indices (Sc) were calculated as described (Lawrence, 1993, J MoI Biol. 234: 946-950) using the Sc program in CCP4 (CCP4, 1994, Acta Crystallogr D Biol Crystallogr, D50: 760-763).

15 Groove surface area calculations were performed as previously described (Lebron et al,

1998, Cell, 93: 111-123; Zeng et al., 1997, Science, 211: 339-345). Structural superpositions were performed using LSQMAN (Kleywegt, 1996, Acta Cryst D Biol Crystallogr, 52: 842- 857). Figures were prepared with MOLSCRIPT (Kraulis, 1991, J Appl Crystallogr, 24: 946),

RASTER-3D (Merritt et al, 1994, Acta Crystallogr D Biol Crystallogr, 50:869-873), and 20

PyMOL (DeLano, 2002, The PyMOL Molecular Graphics System, Delano Scientific, San

Carlos, Ca). The domain angle displacement for the 2L α.3 domain relative to the HLA- A2 α3 domain (-42°) was calculated by measuring the angle between the long axes of each domain after alignment of the αl-α2 platforms of both molecules. The long axes of the α3

25 domains were defined using the coordinates of 2L residues Glyl76 and Asnl91 and HLA- A2 residues Glul77 and Hisl92. The second rotation angle (-40°) relating the α3 domains was estimated using the angle defined by 2L Arg270 and Asnl91 and HLA- A2 Val248.

2 _Q Table 3. Data collection and refinement statistics

1 _g 2 _Q 2.0,

Data collection

Resolution (A) 50.0-2.80 (2.90-2.80) 35 Number of observations 368612

Unique reflections 99161

% Complete ^* 96.8 (81.0)

VoI 16.5 (2.3) 65251/C766

^{i i} W ⁽ % ^{)J 8} ^ ⁴⁷ - ²⁾

Refinement

Resolution (A) 50.0-2.80

Reflections in working set |F|>0 93732

Reflections in test set \F\>0 4965

i?free (%) 26.6

No . of protein atoms 21654 No. of water molecules 96

No. of other atoms (carbohydrate) 252

10 Model geometry rmsd bond length (A) 0.007 rmsd angles (deg) 1.48 Ramachandran plot most favored region (%) 80.4 additional allowed region (%) 14.5 generously allowed region (%) 4.0 disallowed region (%) 1.0

Table 3. Values in parentheses indicate the high-resolution shells. ^* Complete is the number of independent reflections/total theoretical number. Rmerge CO= (∑|/(0 - </(Λ)>|/Σ/(/)), where 20 I(ϊ) is the zth observation of the intensity of the hkl reflection and </> is the mean intensity from multiple measurements of the h,k,l reflection. R _crys t (F) = - |-F _Ca i _c (Λ)||/ and are the observed and calculated structure factor amplitudes for the h,k,l reflection. Rf _τee is calculated over reflections in a test set not included 25 in atomic refinement.

[00118] In summary, methods are disclosed for identifying a candidate TNFα-binding compound utilizing the structure, specifications and amino acid residues elucidated from the ,.„ 2L-TNFa crystal structure. Methods are disclosed for assaying candidate TNFα-binding compounds for decreasing TNFα-mediated disease. [00119] While the present invention has been illustrated and described with reference to certain exemplary embodiments, those of ordinary skill in the art will understand that various 35 modifications and changes may be made to the described embodiments without departing from the spirit and scope of the present invention, as defined in the following claims. 65251/C766

Table 4. Coordinates for the YLDV 2L-TNFa complex crystal structure

REMARK coordinates from minimization refinement ATOM 45 CE LYS A 6 -17487 5729 27666 1006012 A

REMARK refinement resolution 500 - 28 A ATOM 46 NZ LYS A 6 17213 681626677 1006131 A

REMARK starting r- 02382 fτee_r= 02663 ATOM 47 C LYS A 6 ■19026 1491 23372 1004302 A

REMARK final r= 02362 free_r= 02658 ATOM 48 O LYS A 6 -18896 0373 23853 1004690 A

REMARK rmsd bonds= 0007428 rrasd angles= 148430 ATOM 49 N PRO A 7 -18661 176722115 1004803 A

REMARK wa= 425322 ATOM 50 CD PRO A 7 -18940 2909 21239 1003231 A

REMARK target= mlfcycles= 1 steps= 200 ATOM 51 CA PROA 7 -18062 0659 21361 1004607 A

REMARK sg= P2(l) a= 101656 b= 170295 c= 122002 alpha= 900 beta= ATOM 52 CB PRO A 7 -17802 1259 19966 1003431 A

92037 gamma= 900 ATOM 53 CC PRO A 7 -17866 2729

REMARK parameter file 1 CNS_TOPPAR protein_rep param 20173 1003318 A

REMARK parameter file 2 CNS_TOPPAR carbohydrate param ATOM 54 C PRO A 7 -16774 0277 22101 1004413 A

REMARK parameter file 3 CNS_TOPP AR water param ATOM 55 O PROA 7 -15997 1144 22524 1004514 A

REMARK molecular structure file generate mtf ATOM 56 N VAL A 8 -16568 -1021 22286 1003079 A

REMARK input coordinates bgroup pdb ATOM 57 CA VAL A 8 -15397 -1489 23002 1003195 A

REMARK reflection flle=p21reproc2 cv ATOM 58 CB VALA 8 -15672 -1495 24526 1003554 A

REMARK ncs= restrain ncs file= ncsr2 def ATOM 59 CGl VALA 8 -16868 -239424832 1003612 A

REMARK Anisotropic B-factor tensor Ucart of atomic model without isotropic ATOM 60 CG2 VAL A 8 -14445 -196925291 1003824 A component ATOM 61 C VALA 8 -15025 -289322571 1003445 A

REMARK BIl= 28814 B22= -12319 B33- -16495 ATOM 62 0 VALA 8 -15851 -3627 22021 1003369 A

REMARK B12= 0000 BB= -8113 B23= 0000 ATOM 63 N ALAA 9 -13780 -3270 22841 1003626 A

REMARK Isotropic component added to coordinate array B 0835 ATOM 64 CA ALAA 9 -13327 -4598 22494 1004250 A

REMARK bulk solvent probe radius- 1, shrink value=l ATOM 65 CB ALAA 9 -13176 -472720992 1003589 A

REMARK bulk solvent density level= 035 e/A ^Λ 3,B-factor= 461722 A ^Λ 2 ATOM 66 C ALAA 9 -12018 -4921 23157 1004348 A

REMARK reflections with |Fobs|/sigma_F < 00 rejected ATOM 67 O ALA A 9 -11 121 -409223213 1004146 A

REMARK reflections with |Fobsj > 10000 * rms(Fobs) rejected ATOM 68 N HISA lO - ■11924 -6132 23681 1003522 A

REMARK ffigπdding factor =03333, B factor offset =190633 A ^Λ 2 Elimit - 8 ATOM 69 CA HISA 10 10703 -660724294 1003609 A

REMARK theoretical total number of refl in resol range 101928(1000%) ATOM 70 CB HIS A 10 -10793 -6569 25811 1003890 A

REMARK number of unobserved reflections (no entry or |F|=0) 3231 ( 32 % ) ATOM 71 CG HIS A 10 -9537 -7019 26496 1004039 A

REMARK number of reflections rejected 0( 00%) ATOM 72 CD2 HIS A 10 -9205 -8205 27060 1003812 A

REMARK total number of reflections used 98697( 968%) ATOM 73 NDl HISA 10 -8426 -621026621 1004053 A

REMARK number of reflections in working set 93732( 920%) ATOM 74 CEl HIS A 10 _7464 -688027232 1004088 A

REMARK number of reflections in test set 4965 ( 49%) ATOM 75 NE2 HIS A 10 -7912 -809227509 1003836 A

CRYSTl 101656 170295 122002 90009204 9000 P 21 ATOM 76 C HISA 10 10613 -8045 23827 1003430 A

REMARK ATOM 77 O HIS A 10 - -11260 -8933 24394 I 003246 A

FILENAME-"/Users/pamela/Desktop/apw/2L/p21/cns38new/xpand 3/mimmizep ATOM 78 N VALA 11 -9847 -8276 22770 I 003201 A d" ATOM 79 CA VALA 11 9703 -9615 22245 1003459 A

REMARK DATE 27-Mar-2009 165111 created by user pamela ATOM 80 CB VALA 11 -9786 -9619 20731 1002834 A

REMARK VERSION 12 ATOM 81 CGl VALA 11 -11137 -910720332 1002440 A

ATOM 1 CB ARGA 1 -25527 -6064 32919 10016447 A ATOM 82 CG2VALA 11 -8668 -875720121 1003032 A

ATOM 2 CG ARG A 1 -24524 -6994 32215 10016447 A ATOM 83 C VALA 11 -8389-10205 22709 1003320 A

ATOM 3 CD ARGA 1 -25162 -8235 31583 10016447 A ATOM 840 VALA U -7422 -9483 23011 1003021 A

ATOM 4 NE ARG A 1 -25525 -8043 30176 10016447 A ATOM 85 N VALA 12 -8352-11525 22775 1004619 A

ATOM 5 CZ ARG A 1 -24654 -7821 29193 10016447 A ATOM 86 CA VALA 12 -7173-1219423268 1004436 A

ATOM 6 NHl ARG A 1 -23354 -7761 29451 10016447 A ATOM 87 CB VALA 12 -7526-12855 24601 1004090 A

ATOM 7 NH2 ARG A 1 -25082 7656 27948 10016447 A ATOM 88 CGl VALA 12 -8400 -1407624349 I 003470 A

ATOM 8 C ARGA 1 -25992 ^733 30830 10020084 A ATOM 89 CG2VALA 12 -6272-1319925359 1004437 A

ATOM 9 O ARGA 1 -25498 -5373 29901 10020084 A ATOM 90 C VALA 12 -6681-13215 22239 1004232 A

ATOM 10 N ARGA 1 27573 6510 31588 10020084 A ATOM 91 0 VALA 12 -7433 -13612 21340 1004216 A

ATOM U CA ARGA 1 -26621 -5450 32030 10020084 A ATOM 92 N ALAA 13 -5420 -1362622360 1005396 A

ATOM 12 N THRA 2 -26020 -3403 30851 10019725 A ATOM 93 CA ALAA 13 -4827 -14584 21425 1005363 A

ATOM 13 CA THRA 2 -25460 -2602 29762 10019725 A ATOM 94 CB ALAA 13 -3314 -14562 21554 1004620 A

ATOM 14 CB THRA 2 -25981 -1140 29806 10010944 A ATOM 95 C ALAA 13 -5331 -16012 21592 1005761 A

ATOM 15 OGlTHRA . 2 -27413 -113429776 10010818 A ATOM 96 O ALAA 13 -5512-16498 22709 1005512 A

ATOM 16 CG2 THR A 2 -25441 -O339 2862I 10011133 A ATOM 97 N ASNA 14 -5543 -16683 20465 1004446 A

ATOM 17 C THRA 2 -23940 -2535 29844 10019725 A ATOM 98 CA ASNA 14 -6017 18058 20455 1004558 A

ATOM 18 O THRA 2 -23403 -1906 30756 10019725 A ATOM 99 CB ASNA 14 -6690-18348 19124 1005251 A

ATOM 19 N PROA 3 -23222 -3191 28909 10020084 A ATOM 100 CG ASNA 14 -7190-19769 19025 1005450 A

ATOM 20 CD PROA 3 -23593 -412027823 1009978 A ATOM 101 ODl ASNA 14 -7686-20182 17976 1005408 A

ATOM 21 CA PROA 3 -21767 -3083 29028 10020084 A ATOM 102 ND2 ASN A 14 -7071 -2052620114 1005662 A

ATOM 22 CB PROA 3 -21275 -364027694 1009802 A ATOM 103 C ASN A 14 -4831 -18994 20641 1004846 A

ATOM 23 CG PROA 3 -22248 -4759 27454 1009789 A ATOM 104 O ASN A 14 -3945-19045 19787 1004898 A

ATOM 24 C PROA 3 -21415 -160929249 10020084 A ATOM 105 N PROA 15 -4801-1975521751 1007199 A

ATOM 25 O PROA 3 -20477 -1295 29983 10020084 A ATOM 106 CD PROA 15 -5772 -19803 22854 1003503 A

ATOM 26 N SERA 4 -22198 -0720 28626 10013396 A ATOM 107 CA PROA 15 -3687 -20679 22002 1007559 A

ATOM 27 CA SERA 4 -22032 0731 28759 10013053 A ATOM 108 CB PROA 15 -3839 -21035 23483 1003937 A

ATOM 28 CB SERA 4 -20551 112428863 10010988 A ATOM 109 CG PROA 15 -4879 -20071 24022 I 003764 A

ATOM 29 OG SERA 4 19948 121427585 10011183 A ATOM 110 C PROA 15 -3756 -2192621122 1007680 A

ATOM 30 C SERA 4 -22658 154527632 10013087 A ATOM 111 O PROA 15 -2750 -2260320912 1007883 A

ATOM 31 O SERA 4 -23114 266427871 10013102 A ATOM 112 N GLNA 16 -4947 -2221620609 1008235 A

ATOM 32 N ASPA 5 -22672 098226420 1005992 A ATOM 113 CA GLNA 16 -5160-23389 19770 1008130 A

ATOM 33 CA ASP A 5 -23201 1648 25217 1006003 A ATOM 114 CB GLNA 16 6649 23760 19774 10012284 A

ATOM 34 CB ASP A 5 -24033 2876 25616 10014251 A ATOM 115 CG GLNA 16 -6971 -25194 19357 10012577 A

ATOM 35 CG ASPA 5 -24553 3649 24431 10014251 A ATOM 116 CD GLNA 16 6316-2623020258 10012756 A

ATOM 36 ODlASPA 5 -25094 4755 24642 10014251 A ATOM 117 OElGLNA 16 -6296 -2608221482 10012968 A

ATOM 37 OD2 ASP A 5 -24432 3155 23294 10014107 A ATOM 118 NE2GLNA 16 -5787-27291 19655 10012621 A

ATOM 38 C ASPA 5 -22023 207724309 1005753 A ATOM 119 C GLN A 16 -4678 -23171 18334 1007797 A

ATOM 39 O ASPA 5 -22187 2277 23106 1006104 A ATOM 120 O GLNA 16 -4821-24054 17487 1007854 A

ATOM 40 N LYSA 6 -20835 2199 24903 1005131 A ATOM 121 N ALAA 17 -4106-22001 18059 1008513 A

ATOM 41 CA LYS A 6 -19619 260624199 1004769 A ATOM 122 CA ALAA 17 -3609 -21700 16715 1008889 A

ATOM 42 CB LYS A 6 -18521 300625189 1004683 A ATOM 123 CB ALAA 17 -4318-20483 16151 1005663 A

ATOM 43 CG LYSA 6 -18685 4282 25959 1005324 A ATOM 124 C ALAA 17 -2108-21467 16730 1009339 A

ATOM 44 CD LYSA 6 -17539 437626975 1005685 A ATOM 125 O ALAA 17 -1632-20378 16427 1009503 A 65251/C766

ATOM 126 N GLUA IS -1369-22510 17082 1009277 A ATOM 211 NE ARGA 27 -11612-19542 24039 1004623 A ATOM 127 CA GLUA 18 0083-22443 17150 1009477 A ATOM 212 CZ ARGA 27 -10371 -19931 23764 1004984 A ATOM 128 CB GLUA 18 0662-23845 17358 10012394 A ATOM 213 NHl ARG A 27 -10160-2081422795 1005071 A ATOM 129 CG GLUA 18 0338-24818 16235 10012394 A ATOM 214 NH2ARG A 27 -9343-19436 24458 1004807 A ATOM 130 CD GLUA 18 1041 -26150 16397 10012394 A ATOM 215 C ARGA 27 -13757-15528 27343 1003571 A ATOM 131 OEl GLUA IS 2290-26163 16409 10012394 A ATOM 216 O ARGA 27 -14452-14509 27343 1003585 A ATOM 132 0E2GLUA 18 0345-27180 16513 10012394 A ATOM 217 N ALAA 28 -13273 1609728440 1006651 A ATOM 133 C GLUA IS 0708-21826 15904 1009443 A ATOM 218 CA ALAA 28 -13502-1561629793 1006541 A ATOM 134 O GLUA 18 0179-21953 14794 1009404 A ATOM 219 CB ALAA 28 -12330-16019 30675 10010951 A ATOM 135 N GLYA 19 1837-21151 16110 1008024 A ATOM 220 C ALAA 28 -13753-14131 29936 1006507 A ATOM 136 CA GLYA 19 2554-20534 15013 1007773 A ATOM 221 O ALAA 28 -14893-13677 29953 1006609 A ATOM 137 C GLYA 19 2007-19226 14487 1007623 A ATOM 222 N ASNA 29 -12688-13358 30050 1003516 A ATOM 138 O GLYA 19 2663-18584 13672 1007624 A ATOM 223 CA ASN A 29 -12858-1193030237 1003433 A ATOM 139 N GLNA 20 0824-18819 14936 1007498 A ATOM 224 CB ASNA 29 -12047-11493 31455 1004338 A ATOM 140 CA GLN A 20 0235-17569 14465 1007055 A ATOM 225 CG ASN A 29 -12523-12162 32751 1004344 A ATOM 141 CB GLNA 20 -0749 17863 13336 10011383 A ATOM 226 ODl ASN A 29 -13506 -11742 33360 1004930 A ATOM 142 CG GLNA 20 -1800-18890 13708 10011481 A ATOM 227 ND2ASNA 29 -11826 -13207 33167 1004045 A ATOM 143 CD GLNA 20 -2722-19212 12554 10011457 A ATOM 228 C ASNA 29 -12453-1112629002 1003267 A ATOM 144 OEl GLN A 20 -2274-19666 11504 10011422 A ATOM 229 O ASNA 29 -11540 -1030429050 1003039 A ATOM 145 NE2GLNA 20 -4020-18976 12739 10011402 A ATOM 230 N ALAA 30 -13150-11369 27896 1004608 A ATOM 146 C GLNA 20 0463-16786 15574 1006529 A ATOM 231 CA ALAA 30 -12877 -1068426644 1004090 A ATOM 147 O GLN A 20 -0662-17291 16681 1006400 A ATOM 232 CB ALA A 30 -12545-11701 25566 1003084 A ATOM 148 N LEUA 21 -0833-15546 15271 1005800 A ATOM 233 C ALAA 30 -14094 -9858 26246 1004230 A ATOM 149 CA LEUA 21 -1507-14690 16240 1005446 A ATOM 234 O ALAA 30 -15170-10012 26828 1004645 A ATOM 150 CB LEUA 21 -0740-13375 16406 1004922 A ATOM 235 N LEUA 31 -13928 -8982 25262 1004603 A ATOM 151 CG LEUA 21 -1324-12305 17334 1004800 A ATOM 236 CA LEUA 31 15032 8133 24839 1004550 A ATOM 152 CDl LEUA 21 -1741 -12912 18651 1004530 A ATOM 237 CB LEUA 31 14995 -680425587 1002752 A ATOM 153 CD2LEUA 21 -0277-11224 17555 1005004 A ATOM 238 CG LEUA 31 -15337 -670927068 1003040 A ATOM 154 C LEUA 21 -2923-14397 15792 1005307 A ATOM 239 CDl LEUA 31 -14889 -5348 27602 1002802 A ATOM 155 O LEUA 21 -3160-13442 15061 1004839 A ATOM 240 CD2LEUA 31 -16825 -6900 27250 1002987 A ATOM 156 N GLNA 22 -3861 -15221 16237 1006339 A ATOM 241 C LEUA 31 -15039 -7823 23361 1004476 A ATOM 157 CA GLNA 22 -5261 15063 15872 1006799 A ATOM 242 O LEUA 31 -13987 -7738 22735 1004557 A ATOM 158 CB GLNA 22 -5795-16412 15395 1006919 A ATOM 243 N LEUA 32 -16244 -7648 22826 1004002 A ATOM 159 CG GLNA 22 -7282-16458 15141 1007596 A ATOM 244 CA LEUA 32 -16457 -7287 21436 1003981 A ATOM 160 CD GLNA 22 -7775 17877 14986 1008218 A ATOM 245 CB LEUA 32 -16271 -848420515 1003594 A ATOM 161 OEl GLNA 22 -8977-18123 14899 1008741 A ATOM 246 CG LEU A 32 -16407 -8091 19036 1003452 A ATOM 162 NE2GLNA 22 -6844-18824 14950 1008294 A ATOM 247 CDl LEU A 32 -15254 -7162 18642 1003350 A ATOM 163 C GLNA 22 -6065-14550 17075 1006538 A ATOM 248 CD2 LEU A 32 -16419 -9335 18158 1003484 A ATOM 164 O GLNA 22 -6032-15153 18148 1006433 A ATOM 249 C LEUA 32 -17900 -6812 21396 1003945 A ATOM 165 N TRPA 23 -6789-13446 16899 1004636 A ATOM 250 O LEUA 32 -18807 -7577 21058 1004532 A ATOM 166 CA TRPA 23 -7565-12864 17995 1004024 A ATOM 251 N ALAA 33 -18122 -5542 21733 1004398 A ATOM 167 CB TRPA 23 -7700-11347 17822 1003815 A ATOM 252 CA ALA A 33 -19480 -503021770 1004450 A ATOM 168 CG TRPA 23 -6413-10604 17656 1003867 A ATOM 253 CB ALA A 33 -19991 -5087 23186 1001430 A ATOM 169 CD2TRPA 23 -5406-10392 18656 1003678 A ATOM 254 C ALAA 33 -19745 -3653 21215 1004629 A ATOM 170 CE2TRPA 23 -4375 -9640 18059 1003840 A ATOM 255 O ALAA 33 -18839 -2913 20856 1005047 A ATOM 171 CE3TRPA 23 -5276-10769 19999 1003647 A ATOM 256 N ASN A 34 -21037 -3342 21 163 1004470 A ATOM 172 CDl TRPA 23 -5966 -9990 16533 1003814 A ATOM 257 CA ASN A 34 21542 -207420695 1004189 A ATOM 173 NEl TRPA 23 -4744 -9405 16764 1003723 A ATOM 258 CB ASN A 34 21250 1014 21731 1004850 A ATOM 174 CZ2TRPA 23 -3227 -9256 18754 1004046 A ATOM 259 CG ASN A 34 -21876 -1343 23050 1005242 A ATOM 175 CZ3TRPA 23 -4132-10386 20693 1004091 A ATOM 260 ODl ASN A 34 -23067 -1638 23122 1005490 A ATOM 176 CH2TRPA 23 -3124 -9638 20067 1003872 A ATOM 261 ND2ASNA 34 -21083 -1306 24106 1004783 A ATOM 177 C TRPA 23 -8974-13432 18135 1004074 A ATOM 262 C ASNA 34 -21059 -1617 19341 1004264 A ATOM 178 O TRPA 23 -9668-13643 17146 1004202 A ATOM 263 O ASNA 34 -20737 -0445 19152 1004518 A ATOM 179 N LEUA 24 -9399-13677 19370 1003576 A ATOM 264 N GLYA 35 -21003 -2537 18389 1004176 A ATOM 180 CA LEU A 24 -10754-14162 19606 1003345 A ATOM 265 CA GLYA 35 20614 -2137 17060 1003635 A ATOM 181 CB LEUA 24 -10801 -15638 20018 1007548 A ATOM 266 C GLYA 35 -19269 -2539 16526 1003670 A ATOM 182 CG LEUA 24 9618-16569 19826 1007621 A ATOM 267 O GLYA 35 -19152 -2771 15320 1003819 A ATOM 183 CDl LEUA 24 -8550-16204 20825 1007783 A ATOM 268 N VALA 36 -18239 -2612 17362 1003933 A ATOM 184 CD2LEUA 24 -10066-17993 20048 1007132 A ATOM 269 CA VALA 36 -16949 -2972 16795 1004066 A ATOM 185 C LEUA 24 -11382-13350 20711 1004031 A ATOM 270 CB VALA 36 -15766 -2653 17771 1003715 A ATOM 186 O LEUA 24 -10693 -12738 21527 1003729 A ATOM 271 CGl VALA 36 -16303 -2242 19105 1003518 A ATOM 187 N ASNA 25 -12702-1336420731 1003929 A ATOM 272 CG2 VALA 36 -14823 -3826 17890 1003755 A ATOM 188 CA ASNA 25 -13457-12635 21723 1004073 A ATOM 273 C VALA 36 -16980 -4427 16365 1004481 A ATOM 189 CB ASNA 25 14317-11597 21027 1003385 A ATOM 274 O VALA 36 -17535 -5287 17047 1004577 A ATOM 190 CG ASNA 25 -15489-12225 20312 1003542 A ATOM 275 N GLUA 37 -16408 4686 15198 1004354 A ATOM 191 ODl ASNA 25 -16647-12030 20704 1003941 A ATOM 276 CA GLUA 37 -16377 6026 14640 1004614 A ATOM 192 ND2 ASNA 25 -15198-13010 19269 1003182 A ATOM 277 CB GLUA 37 17008 6009 13254 1005470 A ATOM 193 C ASNA 25 -14376 -1359622482 1004126 A ATOM 278 CG GLU A 37 -18199 -5081 13174 1006173 A ATOM 194 O ASNA 25 -15096-1318723391 1004362 A ATOM 279 CD GLUA 37 -18630 -4783 11753 1006470 A ATOM 195 N ARGA 26 -14370-14866 22101 1005177 A ATOM 280 OEl GLU A 37 -17756 -4794 10848 1006813 A ATOM 196 CA ARGA 26 -15227 -15849 22749 1005305 A ATOM 281 OE2GLUA 37 -19840 -4517 11550 1006526 A ATOM 197 CB ARGA 26 -15624-16938 21749 1004300 A ATOM 282 C GLU A 37 -14952 -6548 14544 1004503 A ATOM 198 CG ARGA 26 14460 17626 21065 I 004391 A ATOM 283 O GLUA 37 -13987 -5785 14472 1004749 A ATOM 199 CD ARGA 26 -14930-18861 20344 1004797 A ATOM 284 N LEU A 38 -14831 -7865 14577 1005699 A ATOM 200 NE ARG A 26 -13844-19554 19653 1004911 A ATOM 285 CA LEU A 38 -13541 -8502 14451 1005903 A ATOM 201 CZ ARG A 26 13396-19224 18447 1004967 A ATOM 286 CB LEUA 38 -13353 -9531 15565 1003682 A ATOM 202 NHl ARG A 26 -13946-18205 17794 1005015 A ATOM 287 CG LEU A 38 -11990-10237 15590 1003473 A ATOM 203 NH2 ARG A 26 -12410-19916 17895 1004870 A ATOM 288 CDl LEU A 38 -10878 -9196 15482 1003311 A ATOM 204 C ARG A 26 -14595-1650423970 1005111 A ATOM 289 CD2 LEU A 38 -11842-11072 16859 1003160 A ATOM 205 O ARGA 26 -14641 -17729 24111 1005082 A ATOM 290 C LEUA 38 -13650 -9156 13078 1005930 A ATOM 206 N ARGA 27 -14011-1569924854 1003432 A ATOM 291 O LEUA 38 -14318-10171 12905 1005291 A ATOM 207 CA ARG A 27 -13382-16238 26048 I 003525 A ATOM 292 N ARG A 39 -13014 -8537 12094 1004284 A ATOM 208 CB ARG A 27 11867-16241 25883 1003905 A ATOM 293 CA ARG A 39 13063 -9000 10709 1004937 A ATOM 209 CG ARG A 27 -11385-17198 24836 1004047 A ATOM 294 CB ARG A 39 -13799 -7953 9884 1005015 A ATOM 210 CD ARGA 27 -11958-18577 25082 1004284 A ATOM 295 CG ARGA 39 -14177 -8376 8509 1005785 A 65251/C766

ATOM 296 CD ARG A 39 -15142 -7372 7924 1006646 A ATOM 381 CD2 LEU A 50 -10887 12726 21669 1003462 A ATOM 297 NE ARG A 39 -15754 -7883 6705 1007299 A ATOM 382 C LEU A 50 -11473 7944 20512 1004086 A ATOM 298 CZ ARG A 39 -16815 -7337 6122 1007379 A ATOM 383 O LEU A 50 -12417 7541 21 183 1003958 A ATOM 299 NHl ARG A 39 -17384 -6253 6646 1007227 A ATOM 384 N TYRA 51 -10414 7190 20265 1004346 A ATOM 300 NH2 ARG A 39 -17317 -7883 5024 I 007609 A ATOM 385 CA TYR A 51 10322 5829 20798 1004211 A ATOM 301 C ARG A 39 -11 667 -9224 10150 1005142 A ATOM 386 CB TYR A 51 -10456 4787 19681 1003604 A ATOM 302 O ARG A 39 -10801 -8369 10268 1005465 A ATOM 387 CG TYR A 51 11838 4612 19104 1003614 A ATOM 303 N ASP A 40 -11447-10382 9551 1005229 A ATOM 388 CDl TYR A 51 -12386 5568 18257 1003700 A ATOM 304 CA ASP A 40 -10149-10715 8976 1005024 A ATOM 389 CEl TYR A 51 -13653 5397 17710 1003656 A ATOM 305 CB ASP A 40 -9925 9917 7684 10011416 A ATOM 390 CD2 TYR A 51 -12593 3479 19398 1003770 A ATOM 306 CG ASP A 40 -11043-10114 6669 10011630 A ATOM 391 CE2 TYR A 51 -13861 3296 18863 1003597 A ATOM 307 ODl ASP A 40 -11341-11280 6332 100113 18 A ATOM 392 CZ TYR A 51 -14384 4254 18018 1003567 A ATOM 308 OD2 ASP A 40 11623 -9106 6204 10011642 A ATOM 393 OH TYR A 51 -15631 4060 17472 1003590 A ATOM 309 C ASP A 40 -9012-10444 9966 1004637 A ATOM 394 C TYRA 51 -9019 5528 21515 1004229 A ATOM 310 O ASP A 40 -7927 -9986 9591 1004560 i \ ATOM 395 O TYR A 51 -7940 5972 21 104 1004318 A ATOM 311 N ASN A 41 -9273-10724 11238 1005536 A ATOM 396 N LEU A 52 -9119 4759 22589 1004038 A ATOM 312 CA ASN A 41 -8293-10541 12316 10051 11 A ATOM 397 CA LEU A 52 -7928 4347 23311 1004203 A ATOM 313 CB ASN A 41 -6996-11278 11999 1004873 A ATOM 398 CB LEU A 52 -8200 4229 24812 1003833 A ATOM 314 CG ASN A 41 -6260-11701 13252 1004342 A ATOM 399 CG LEU A 52 -7100 3529 25617 1003422 A ATOM 315 ODl ASN A 41 -6835-12365 14134 1004476 A ATOM 400 CDl LEU A 52 -5758 4169 25340 1003625 A ATOM 316 ND2 ASN A 41 -4987-11332 13345 1003952 A ATOM 401 CD2 LEU A 52 -7441 3601 27090 1002855 A ATOM 317 C ASN A 41 -7965 -9095 12649 1005442 A ATOM 402 C LEU A 52 -7633 2983 22705 1004356 A ATOM 318 O ASN A 41 -6886 -8799 13162 1005593 A ATOM 403 O LEU A 52 8486 2100 22709 1004413 A ATOM 319 N GLN A 42 -8901 -8199 12359 1006244 A ATOM 404 N ILE A 53 -6443 2832 22143 1004095 A ATOM 320 CA GLN A 42 -8708 -6785 12638 1006036 A ATOM 405 CA ILE A 53 -6048 1579 21521 1003755 A ATOM 321 CB GLN A 42 -8444 -6018 11348 1004814 A ATOM 406 CB ILE A 53 -5605 1800 20069 1004746 A ATOM 322 CG GLN A 42 -7415 -6661 10459 1005023 A ATOM 407 CG2 ILE A 53 -5262 0481 19416 1004810 A ATOM 323 CD GLN A 42 -7232 -5926 9139 1 004969 A ATOM 408 CGl ILE A 53 -6716 2475 19285 1004635 A ATOM 324 OEl GLN A 42 -8206 -5606 8449 1004912 A ATOM 409 CDl ILE A 53 -6323 2754 17864 1004217 A ATOM 325 NE2 GLN A 42 -5973 -5667 8775 1005145 A ATOM 410 C ILE A 53 -4870 1018 22286 1003761 A ATOM 326 C GLN A 42 -9966 -6239 13286 1005925 A ATOM 411 O ILE A 53 -3976 1757 22678 1004069 A ATOM 327 O GLN A 42 11073 -6701 13006 1 005959 A ATOM 412 N TYR A 54 -4857 -0287 22500 1004380 A ATOM 328 N LEU A 43 -9796 -5264 14167 1003912 A ATOM 413 CA TYR A 54 -3745 -0887 23226 1004093 A ATOM 329 CA LEU A 43 -10944 -4660 14807 1003770 A ATOM 414 CB TYR A 54 -3957 -0718 24729 1003958 A ATOM 330 CB LEU A 43 10549 -4089 16165 1002932 A ATOM 415 CG TYR A 54 -5167 -1459 25243 1003958 A ATOM 331 CG LEU A 43 -10082 -5131 17180 1003548 A ATOM 416 CDl TYR A 54 -5075 -2792 25641 1003958 A ATOM 332 CDl LEU A 43 -9511 -4441 18410 1003557 A ATOM 417 CEl TYR A 54 -6194 -3492 26065 I 003958 A ATOM 333 CD2 LEU A 43 -11241 -6016 17544 1003187 A ATOM 418 CD2 TYR A 54 -6414 -0843 25285 1003958 A ATOM 334 C LEU A 43 -11444 -3551 13877 1003972 A ATOM 419 CE2 TYR A 54 -7544 1537 25708 1003958 A ATOM 335 O LEU A 43 -10650 -2830 13280 1003634 A ATOM 420 CZ TYR A 54 -7425 -2859 26093 1003958 A ATOM 336 N VALA 44 -12757 -3427 13739 1004400 A ATOM 421 OH TYR A 54 -8538 -3554 26480 1003958 A ATOM 337 CA VAL A 44 -13316 -2408 12874 1004368 A ATOM 422 C TYR A 54 -3554 2363 22887 1003952 A ATOM 338 CB VAL A 44 -14135 -3035 11749 1004683 A ATOM 423 O TYR A 54 -4459 -3020 22368 1003837 A ATOM 339 CGl VAL A 44 -14553 -1967 10763 1004802 A ATOM 424 N SER A 55 -2364 -2870 23183 1002857 A ATOM 340 CG2 VAL A 44 -13313 -4112 11063 1004144 A ATOM 425 CA SER A 55 2063 -4259 22909 1002835 A ATOM 341 C VALA 44 -14198 -1435 13650 1004269 A ATOM 426 CB SER A 55 -1877 -4467 21420 1004260 A ATOM 342 O VALA 44 -15232 -1817 14221 1 004373 A ATOM 427 OG SER A 55 -1363 -5756 21 183 1004916 A ATOM 343 N VAL A 45 -13778 -0171 13649 1 003256 A ATOM 428 C SER A 55 -0817 ^730 23620 1003133 A ATOM 344 CA VAL A 45 -14480 0892 14350 1003830 A ATOM 429 O SER A 55 0097 -3947 23870 1002847 A ATOM 345 CB VAL A 45 -13603 2151 14391 1005443 A ATOM 430 N GLN A 56 -0790 -6011 23965 1004014 A ATOM 346 CGl VAL A 45 -14405 3341 14869 1005700 A ATOM 431 CA GLN A 56 0380 -6575 24609 1004084 A ATOM 347 CG2 VAL A 45 -12435 1912 15319 1005783 A ATOM 432 CB GLN A 56 0228 -6662 26117 1005688 A ATOM 348 C VAL A 45 -15837 1203 13711 1004009 A ATOM 433 CG GLN A 56 1520 -7130 26755 1005848 A ATOM 349 O VALA 45 -15949 1350 12502 1003954 A ATOM 434 CD GLN A 56 1350 -7579 28182 1006160 A ATOM 350 N PRO A 46 -16887 1311 14534 1004197 A ATOM 435 OEl GLN A 56 0919 -8704 28442 1006113 A ATOM 351 CD PRO A 46 -16909 0906 15954 1003818 A ATOM 436 NE2 GLN A 56 1689 -6702 29126 1006471 A ATOM 352 CA PRO A 46 -18239 1598 14053 1004082 A ATOM 437 C GLN A 56 0658 -7967 24096 1004332 A ATOM 353 CB PRO A 46 -19102 0810 15021 1003754 A ATOM 438 O GLN A 56 -0254 -8780 23954 1004140 A ATOM 354 CG PRO A 46 -18377 1071 16326 1003824 A ATOM 439 N VAL A 57 1926 -8231 23804 1004464 A ATOM 355 C PRO A 46 -18644 3070 14001 1004426 A ATOM 440 CA VAL A 57 2331 -9546 23345 1003901 A ATOM 356 O PRO A 46 -19725 3390 13522 1004672 A ATOM 441 CB VALA 57 2850 -9528 21897 1004166 A ATOM 357 N SER A 47 -17805 3972 14490 1005778 A ATOM 442 CGl VAL A 57 1784 -8991 20980 1004286 A ATOM 358 CA SER A 47 -18181 5379 14459 1005490 A ATOM 443 CG2 VAL A 57 4112 -8700 21807 1003859 A ATOM 359 CB SER A 47 -19234 5650 15532 1006377 A ATOM 444 C VAL A 57 3448 -9996 24266 1004162 A ATOM 360 OG SER A 47 -18721 5351 16816 1006498 A ATOM 445 O VAL A 57 4172 -9173 24827 1004273 A ATOM 361 C SER A 47 -17023 6356 14639 1005159 A ATOM 446 N LEU A 58 3569 -11306 24440 1005066 A ATOM 362 O SER A 47 -15974 5995 15178 1004873 A ATOM 447 CA LEU A 58 4613-11855 25289 1004911 A ATOM 363 N GLU A 48 -17226 7594 14177 1005164 A ATOM 448 CB LEU A 58 4005-12580 26485 1005263 A ATOM 364 CA GLU A 48 -16230 8662 14297 1005613 A ATOM 449 CG LEU A 58 4851 -12634 27755 1005465 A ATOM 365 CB GLU A 48 16804 9996 13813 10017315 A ATOM 450 CDl LEU A 58 4381 -13803 28607 1004867 A ATOM 366 CG GLU A 48 -17350 10009 12399 10017789 A ATOM 451 CD2 LEU A 58 6313-12794 27407 1005243 A ATOM 367 CD GLU A 48 -16274 10201 11351 10018224 A ATOM 452 C LEU A 58 5420 -12836 24456 1005208 A ATOM 368 OEl GLU A 48 -15453 9281 11 160 10018398 A ATOM 453 O LEU A 58 4895-13845 23981 1005371 A ATOM 369 OE2 GLU A 48 -16248 11280 10721 10018016 A ATOM 454 N PHE A 59 6693-12521 24258 1004871 A ATOM 370 C GLU A 48 -15939 8792 15788 1005472 A ATOM 455 CA PHE A 59 7558-13398 23488 1004961 A ATOM 371 O GLUA 48 -16815 8533 16617 1006051 A ATOM 456 CB PHEA 59 8549 -12595 22639 1006142 A ATOM 372 N GLY A 49 -14721 9185 16137 1003548 A ATOM 457 CG PHE A 59 7910-11779 21562 1005791 A ATOM 373 CA GLY A 49 -14419 9354 17543 10033 14 A ATOM 458 CDl PHE A 59 7757-10409 21714 1005635 A ATOM 374 C GLY A 49 -12995 9137 18002 1003515 A ATOM 459 CD2 PHE A 59 7481 -12379 20387 1005987 A ATOM 375 O GLY A 49 -12124 8683 17251 1003799 A ATOM 460 CEl PHE A 59 7187 9643 20710 1006227 A ATOM 376 N LEU A 50 -12777 9485 19261 1004328 A ATOM 461 CE2 PHE A 59 6910-11628 19374 1006298 A ATOM 377 CA LEU A 50 -11490 9348 19914 1004448 A ATOM 462 CZ PHE A 59 6762-10256 19533 1006158 A ATOM 378 CB LEU A 50 -11392 10407 21017 1003310 A ATOM 463 C PHE A 59 8333 -14310 24435 1005372 A ATOM 379 CG LEU A 50 -10360 11527 20919 1003423 A ATOM 464 O PHE A 59 8695-13912 25545 1005341 A ATOM 380 CDl LEU A 50 -10056 11856 19479 1003104 A ATOM 465 N LYS A 60 8580 -15535 23982 1008680 A 65251/C766

ATOM 466 CA LYSA 60 9321-16512 24766 1008815 A ATOM 551 CA THRA 72 8500 6103 16759 1006348 A

ATOM 467 CB LYSA 60 8367-17418 25539 1006786 A ATOM 552 CB THRA 72 8682 -5539 15339 1006528 A

ATOM 468 CG LYSA 60 9060-18534 26304 1007405 A ATOM 553 OGl THRA 72 7885 6292 14415 1006781 A

ATOM 469 CD LYSA 60 8041-19423 26991 1008226 A ATOM 554 CG2THRA 72 10136 -5603 14932 1006300 A

ATOM 470 CE LYSA 60 8706 -20563 27737 1008501 A ATOM 555 C THRA 72 7008 -6303 16981 1006611 A

ATOM 471 NZ LYSA 60 7690-21401 28430 1008535 A ATOM 556 O THRA 72 6437 -7343 16628 1006715 A

ATOM 472 C LYSA I 50 10166-1736023842 1008766 A ATOM 557 N HlSA 73 6388 -5289 17574 1004767 A

ATOM 473 O LYSA 60 9712-17774 22777 1009041 A ATOM 558 CA HIS A 73 4964 -5307 17853 1004812 A

ATOM 474 N GLYA 61 11397-17618 24255 1007354 A ATOM 559 CB HISA 73 4719 -5389 19357 1005738 A

ATOM 475 CA GLYA 61 12276-18425 23437 1007610 A ATOM 560 CG HlSA 73 3277 -5513 19719 1006025 A

ATOM 476 C GLYA 61 13151-19318 24282 1007780 A ATOM 561 CD2 HIS A 73 2207 -5898 18987 1006201 A

ATOM 477 O GLYA 61 13572-18931 25367 1008097 A ATOM 562 NDl HIS A 73 2800 -5235 20982 1006486 A

ATOM 478 N GLNA 62 13413-20523 23789 10011369 A ATOM 563 CEl HIS A 73 1496 -5442 21013 1006340 A

ATOM 479 CA GLNA 62 14258-21473 24496 10011400 A ATOM 564 NE2 HIS A 73 1 112 -5846 19815 1 006357 A

ATOM 480 CB GLNA 62 13862 22907 24136 10011881 A ATOM 565 C HIS A 73 4487 -3976 17327 1004720 A

ATOM 481 CG GLNA 62 12408-2324624415 10012294 A ATOM 566 O HISA 73 5119 -2952 17571 1004306 A

ATOM 482 CD GLNA 62 12072 -23195 25892 10012888 A ATOM 567 N THRA 74 3390 -3971 16591 1003640 A

ATOM 483 OE 1 GLNA . 62 12218-22158 26538 10012848 A ATOM 568 CA THRA 74 2919 -2718 16045 1004299 A

ATOM 484 NE2 GLN A L 62 11619-24319 26435 10012905 A ATOM 569 CB THRA 74 3764 -2332 14774 1005066 A

ATOM 485 C GLNA 62 15680-21203 24037 10011194 A ATOM 570 OGl THRA 74 2899 -1913 13713 1005317 A

ATOM 486 O GLNA 62 15971-2128422845 10011345 A ATOM 571 CG2THRA 74 4618 -3503 14306 1005549 A

ATOM 487 N GLYA 63 16560-20870 24975 10010190 A ATOM 572 C THRA 74 1424 2706 15740 10041 84 A

ATOM 488 CA GLYA 63 17938-20588 24614 1009989 A ATOM 573 O THRA 74 0864 -3699 15286 1003742 A

ATOM 489 C GLYA 63 18019-1952623531 1009797 A ATOM 574 N ILEA 75 0776 -1583 16029 1005382 A

ATOM 490 O GLYA 63 17017-18889 23219 1009601 A ATOM 575 CA ILEA 75 -0647 -1435 15765 1005512 A

ATOM 491 N CYSA 64 19197-19343 22939 10011595 A ATOM 576 CB ILEA 75 -1396 -0839 16974 1003445 A

ATOM 492 CA CYSA 64 19366-18328 21903 10012019 A ATOM 577 CG2 ILE A 75 -2852 -0579 16619 1003394 A

ATOM 493 C CYSA 64 19663-18799 20490 10012628 A ATOM 578 CGl ILEA 75 -1302 -1 804 18158 1 003161 A

ATOM 494 O CYSA 64 20406-19754 20278 10012919 A ATOM 579 CDl ILEA 75 -2023 -1325 19390 1003490 A

ATOM 495 CB CYSA 64 20437-1733422326 0013040 A ATOM 580 C ILEA 75 -0787 -0491 14583 1005826 A

ATOM 496 SG CYSA 64 19776-16115 23489 0013161 A ATOM 581 O ILEA 75 -0305 0647 14621 1005503 A

ATOM 497 N PROA 65 19068-18122 19497 10012537 A ATOM 582 N SER A 76 -1443 -0970 13532 1005670 A

ATOM 498 CD PROA 65 17941-17190 19664 10014261 A ATOM 583 CA SERA 76 -1631 -0184 12327 1005778 A

ATOM 499 CA PROA 65 19253-18448 18082 10012771 A ATOM 584 CB SERA 76 -1209 -0983 11098 1005229 A

ATOM 500 CB PROA 65 18138-17658 17393 10014514 A ATOM 585 OG SERA 76 0133 -1405 11208 1006158 A

ATOM 501 CG PROA 65 17101-17513 18461 10014487 A ATOM 586 C SERA 76 -3064 0233 12125 1005378 A

ATOM 502 C PROA 65 20629-18018 17595 10013072 A ATOM 587 O SERA 76 -3995 -0405 12621 1004993 A

ATOM 503 O PROA 65 21585-17946 18367 10013099 A ATOM 588 N ARGA 77 3231 1321 11384 1004334 A

ATOM 504 N SERA 66 20711 -17722 16305 10017892 A ATOM 589 CA ARG A 77 -4549 1806 11039 1004852 A

ATOM 505 CA SERA 66 21955-17295 15690 10018252 A ATOM 590 CB ARG A 77 -4784 3231 Il 542 1003905 A

ATOM 506 CB SERA 66 22077-17907 14293 10016062 A ATOM 591 CG ARG A 77 -5906 3930 10771 1004123 A

ATOM 507 OG SERA 66 23265-17484 13651 10015778 A ATOM 592 CD ARG A 77 -6560 5051 11 549 1004210 A

ATOM 508 C SERA i 56 21998-15775 15595 10018307 A ATOM 593 NE ARG A 77 -6212 6386 11068 1004454 A

ATOM 509 O SERA 66 21037 15093 15953 10017649 A ATOM 594 CZ ARG A 77 -7106 7307 10718 1004797 A

ATOM 510 N THRA 67 23126-15263 15111 10020072 A ATOM 595 NHl ARG A 77 -6708 8496 10298 1004806 A

ATOM 511 CA THRA 67 23355-13830 14938 10020072 A ATOM 596 NH2 ARG A 77 -8402 7036 10770 1004783 A

ATOM 512 CB THRA 67 23038-13385 13488 10016899 A ATOM 597 C ARGA 77 -4635 1814 9523 1004686 A

ATOM 513 OGl THRA 67 23758-14211 12564 10016899 A ATOM 598 O ARGA 77 -3716 2262 8852 1005261 A

ATOM 514 CG2 THR / i 67 23444-11928 13274 10016899 A ATOM 599 N ILEA 78 -5716 1272 8983 1004721 A

ATOM 515 C THRA 67 22558 12948 15892 10020072 A ATOM 600 CA ILEA 78 -5926 1320 7548 1004590 A

ATOM 516 O THRA 67 22943-12753 17045 10020072 A ATOM 601 CB ILEA 78 -5978 -0110 6879 1005608 A

ATOM 517 N HISA C iδ 21441 -12422 15402 10013945 A ATOM 602 CG2 ILE A 78 -5464 -1 168 7825 1005658 A

ATOM 518 CA HISA 68 20605-11543 16201 10013457 A ATOM 603 CGl ILEA 78 -7378 -0444 6405 1005775 A

ATOM 519 CB HISA 68 21077 10099 16016 10018555 A ATOM 604 CDl ILE A 78 -7790 0325 5179 1005807 A

ATOM 520 CG HISA 68 20682 -9181 17129 10018555 A ATOM 605 C ILEA 78 -7252 2098 7509 1004807 A

ATOM 521 CD2 HIS A 68 19930 8055 17133 10018555 A ATOM 606 O ILEA 78 -8329 1568 7797 1004662 A

ATOM 522 NDl HIS A 68 21095 -9370 18430 10018555 A ATOM 607 N ALAA 79 -7136 3393 7215 1005186 A

ATOM 523 CEl HIS A 68 20615 -8400 19188 10018555 A ATOM 608 CA ALA A 79 -8284 4295 7193 1004846 A

ATOM 524 NE2 HIS A 68 19904 -7589 18425 10018555 A ATOM 609 CB ALAA 79 -7793 5735 7248 1005750 A

ATOM 525 C HlSA t i8 19141-11675 15782 10013040 A ATOM 610 C ALA A 79 -9229 4111 6015 1004966 A

ATOM 526 O HISA ( Ϊ8 18837-11840 14599 10012985 A ATOM 611 O ALAA 79 -8818 3711 4936 I 004986 A

ATOM 527 N VALA 69 18241 -11607 16760 10011298 A ATOM 612 N VALA 80 -10503 4408 6229 1005804 A

ATOM 528 CA VALA 69 16808-11710 16500 10011271 A ATOM 613 CA VALA 80 11489 4278 5168 1006053 A

ATOM 529 CB VALA 69 16185-12924 17226 10012662 A ATOM 614 CB VALA 80 -12911 4599 5674 1007047 A

ATOM 530 CGl VALA 69 14709-13022 16895 10012638 A ATOM 615 CGl VALA 80 -13905 4490 4536 1006887 A

ATOM 531 CG2 VAL A 69 16901 -14203 16820 10012488 A ATOM 616 CG2VALA 80 -13295 3656 6781 1007217 A

ATOM 532 C VALA 69 16100-10450 16981 10011230 A ATOM 617 C VALA 80 -11 146 5258 4052 1006508 A

ATOM 533 O VALA 69 16349 -9970 18087 10011586 A ATOM 618 O VALA 80 -11381 4987 2876 1006367 A

ATOM 534 N LEUA 70 15222 -9914 16141 1007621 <V ATOM 619 N SERA 81 10583 6402 4420 1006210 A

ATOM 535 CA . LEUA 70 14473 -8717 16491 1007143 A ATOM 620 CA SERA 81 -10227 7404 3428 1006496 A

ATOM 536 CB LEUA 70 14644 -7633 15426 1008936 A ATOM 621 CB SERA 81 -10448 8797 3993 1006737 A

ATOM 537 CG LEUA 70 16019 6977 15290 1009106 A ATOM 622 OG SERA 81 -U 821 8994 4259 1007041 A

ATOM 538 CDl LEU fl i 70 15935 -5868 14258 1008610 A ATOM 623 C SERA 81 -8803 7295 2901 1006914 A

ATOM 539 CD2 LEU /> i 70 16473 -6418 16627 1009166 A ATOM 624 O SERA 81 -8354 8177 2175 1006966 A

ATOM 540 C LEUA 70 12995 -9028 16641 1007247 A ATOM 625 N TYRA 82 -8099 6220 3257 1005169 A

ATOM 541 O LEUA 70 12411 -9728 15818 1007258 A ATOM 626 CA TYRA 82 -6721 6006 2800 1005373 A

ATOM 542 N LEUA 71 12400 -8503 17704 1007090 A ATOM 627 CB TYRA 82 -5771 6989 3500 10041 69 A

ATOM 543 CA . LEUA 71 10986 -8701 17972 1007084 A ATOM 628 CG TYRA 82 -4372 7001 2925 1004489 A

ATOM 544 CB LEUA 71 10791 -9209 19401 1006208 A ATOM 629 CDl TYR A 82 3260 6692 3721 1004718 A

ATOM 545 CG LEUA 71 11477-10532 19745 1005975 A ATOM 630 CElTYRA 82 -1980 6641 3175 1004897 A

ATOM 546 CDl LEU A 71 11270-10856 21221 1005590 A ATOM 631 CD2TYRA 82 -4161 7270 1567 1004698 A

ATOM 547 CD2 LEU A 71 10910-11 633 18866 1005987 A ATOM 632 CE2TYRA 82 -2887 7226 1013 1004845 A

ATOM 548 C LEUA 71 10283 -7363 17803 1007487 A ATOM 633 CZ TYRA 82 -1803 6908 1816 1004914 A

ATOM 549 O LEUA 71 10690 -6365 18402 1007436 A ATOM 634 OH TYR A 82 -0549 6843 1259 1004756 A

ATOM 550 N THRA 72 9246 -7336 16973 1006605 A ATOM 635 C TYRA 82 -6294 4565 3087 1005316 A 65251/C766

ATOM 636 O TYR A 82 -5 499 4 312 3 989 1 00 53 34 A ATOM 721 N SER A 94 15192 -6485 21452 1006923 A

ATOM 637 N GLN A 83 -6 834 3 632 2 303 1 0061 97 A ATOM 722 CA SER A 94 16257 -7430 21092 1007168 A

ATOM 638 CA GLN A 83 -6565 2 202 2449 1 0061 86 A ATOM 723 CB SER A 94 17544 6669 20770 1008728 A

ATOM 639 CB GLN A 83 -7279 1 407 1 351 00 86 61 A ATOM 724 OG SER A 94 17959 -5877 21876 1008971 A

ATOM 640 CG GLN A 83 -8 611 0 787 1 741 1 00 90 88 A ATOM 725 C SER A 94 16522 -8403 22238 1007427 A

ATOM 641 CD GLN A 83 9 738 1 794 1 783 1 00 91 92 A ATOM 726 O SER A 94 17280 -8101 23 159 1007554 A

ATOM 642 OEl GLN A 83 -10 909 1 42 1 837 1 00 9094 A ATOM 727 N PRO A 95 15916 -9597 22181 1007498 A

ATOM 643 NE2 GLN A 83 -9 392 3 078 1 761 1 00 89 42 A ATOM 728 CD PRO A 95 15186-10141 21024 1006626 A

ATOM 644 C GLN A 83 5 108 1 771 2456 1 006004 A ATOM 729 CA PRO A 95 16075 -10620 23218 1007892 A

ATOM 645 O GLN A 83 -4 646 1 171 1 500 1 00 5749 A ATOM 730 CB PRO A 95 15105-11705 22774 1006920 A

ATOM 646 N THR A 84 -4 381 2 050 3 526 1 0064 19 A ATOM 731 CG PRO A 95 15209 -11 630 21292 1006665 A

ATOM 647 CA THR A 84 -2 993 1 626 3 605 00 56 56 A ATOM 732 C PRO A 95 17495-11 128 23333 1008335 A

ATOM 648 CB THR A 84 -2 045 2 607 2 933 00 89 07 A ATOM 733 O PRO A 95 18224-10765 24255 1008678 A

ATOM 649 OGl THR A 84 -2 526 2 908 1 623 1 00 89 62 A ATOM 734 N CYS A 96 17882 -11976 22390 10016879 A

ATOM 650 CG2 THRA 84 0646 2 001 2 836 1 0091 82 A ATOM 735 CA CYS A 96 19218-12534 22380 10016858 A

ATOM 651 C THR A 84 -2 584 1 543 5 051 1 0053 07 A ATOM 736 C CYS A 96 20195 11536 21794 10016968 A

ATOM 652 O THR A 84 2 915 2 422 5 845 1 00 54 38 A ATOM 737 O CYS A 96 20196-11279 20589 10016998 A

ATOM 653 N LYS A 85 -1 861 0 491 5 401 1 00 50 48 A ATOM 738 CB CYS A 96 19244 -13828 21573 10020084 A

ATOM 654 CA LYS A 85 -1 408 0 352 6 760 00 5034 A ATOM 739 SG CYS A 96 18348 -15190 22378 10020084 A

ATOM 655 CB LYS A 85 -0 647 -0957 6 941 00 7405 A ATOM 740 N GLN A 97 21019-10969 22667 10020084 A

ATOM 656 CG LYS A 85 -I 473 -2 140 7 405 00 7099 A ATOM 741 CA GLN A 97 22024 -9996 22269 10020084 A

ATOM 657 CD LYS A 85 -0 538 -3 307 7 740 00 6939 A ATOM 742 CB GLN A 97 22488 -9210 23496 10014853 A

ATOM 658 CE LYS A 85 -1 272 -4483 8 374 00 67 69 A ATOM 743 CG GLN A 97 21349 -8598 24295 10014853 A

ATOM 659 NZ LYS A 85 -2 299 -5 057 7 458 00 65 94 A ATOM 744 CD GLN A 97 21773 -8193 25692 10014853 A

ATOM 660 C LYS A 85 -0470 1 507 7 095 1 00 50 14 A ATOM 745 OEl GLN A 97 22682 -7380 25868 10014853 A

ATOM 661 O LYS A 85 0512 1 734 6 386 1 00 50 59 A ATOM 746 NE2 GLN A 97 21 115 -8761 26697 10014853 A

ATOM 662 N VAL A 86 -0 795 2 259 8 143 1 00 51 20 A ATOM 747 C GLN A 97 23203 -10744 21647 10020084 A

ATOM 663 CA VALA 86 0073 3 331 8 616 00 5409 A ATOM 748 O GLN A 97 24361 -10449 21943 10020084 A

ATOM 664 CB VAL A 86 -0 530 4754 8 411 1 00 66 12 A ATOM 749 N ARG A 98 22889 -11719 20792 10020084 A

ATOM 665 CGl VAL A 86 -0 71C 5 02« 6 940 1 0072 86 A ATOM 750 CA ARG A 98 23892 -12537 20111 10020084 A

ATOM 666 CG2 VAL A 86 1 85C 4 89C 9 116 1 00 67 39 A ATOM 751 CB ARG A 98 24955-11633 19464 10016585 A

ATOM 667 C VAL A 86 0225 3 012 0098 1 00 54 76 A ATOM 752 CG ARG A 98 26154 12360 18862 10016585 A

ATOM 668 O VAL A 86 -0762 2 771 10 788 005945 A ATOM 753 CD ARG A 98 25766-13268 17706 10016585 A

ATOM 669 N ASN A 87 1 457 2 965 0584 1 006749 A ATOM 754 NE ARG A 98 26881 -14114 17290 10016585 A

ATOM 670 CA ASN A 87 1 695 2 639 11 986 1 00 64 17 A ATOM 755 CZ ARG A 98 28071-13657 16910 10016585 A

ATOM 671 CB ASN A 87 3 172 2 316 12 193 1 00 58 77 A ATOM 756 NHl ARG A 98 29023-14508 16550 10016585 A

ATOM 672 CG ASN A 87 3 599 1 044 11 476 1 00 59 07 A ATOM 757 NH2 ARG A 98 28312-12352 16887 10016585 A

ATOM 673 ODl ASN A 87 2 771 0 295 10941 1 0061 68 A ATOM 758 C ARG A 98 24551 -13557 21051 10020084 A

ATOM 674 ND2 ASN A 87 4900 0 785 11 476 1 00 5603 A ATOM 759 O ARG A 98 25436-14310 20639 10020084 A

ATOM 675 C ASN A 87 1 272 3 712 2 992 1 0062 99 A ATOM 760 N GLU A 99 24103-13591 22306 10020068 A

ATOM 676 O ASN A 87 1 615 4 889 12 845 1 00 61 57 A ATOM 761 CA GLU A 99 24649-14516 23301 10020068 A

ATOM 677 N LEU A 88 0529 3 311 4023 1 00 50 94 A ATOM 762 CB GLU A 99 23711 -14628 24511 10018353 A

ATOM 678 CA LEU A 88 0 105 4252 15 061 1 0049 93 A ATOM 763 CG GLU A 99 22369 -13928 24346 10018353 A

ATOM 679 CB LEU A 88 -1 319 3 981 15 499 1 00 35 26 A ATOM 764 CD GLU A 99 22425-12458 24715 10018353 A

ATOM 680 CG LEU A 88 -2 386 4084 14429 1 00 32 19 A ATOM 765 OEl GLU A 99 23396 11783 24315 10018353 A

ATOM 681 CDl LEU A 88 -3 741 3 814 15 070 1 0032 96 A ATOM 766 OE2 GLU A 99 21494-11977 25398 10018353 A

ATOM 682 CD2 LEU A 88 -2 332 5 460 13 779 1 0030 76 A ATOM 767 C GLU A 99 24891 -15910 22726 10020068 A

ATOM 683 C LEU A 88 1 002 4096 6270 1 00 49 17 A ATOM 768 O GLU A 99 25975 -16468 22884 10020068 A

ATOM 684 O LEU A 88 1 427 5 064 6870 1 0047 54 A ATOM 769 N THRA lOO 23876-16459 22061 10017794 A

ATOM 685 N LEU A 89 1 283 2 852 6622 1 0039 72 A ATOM 770 CA THR A lOO 23949 -17788 21456 I 0017794 A

ATOM 686 CA LEU A 89 2 122 2 538 17 766 1 00 38 64 A ATOM 771 CB THR A lOO 24786-17772 20154 10016357 A

ATOM 687 CB LEU A 89 1 247 2 118 18 940 1 00 3686 A ATOM 772 OGl THR A lOO 26090-17247 20426 10016385 A

ATOM 688 CG LEU A 89 0 117 3 066 19 328 1 0040 84 A ATOM 773 CG2 THR A 100 24113-16913 19095 10016474 A

ATOM 689 CDl LEU A 89 -0916 2 303 20 130 1 0040 57 A ATOM 774 C THR A lOO 24528-18837 22408 10017794 A

ATOM 690 CD2 LEU A 89 0664 4223 20 119 1 00 39 96 A ATOM 775 O THR A lOO 25691 -18762 22805 10017794 A

ATOM 691 C LEU A 89 3 018 1 376 7375 1 00 40 31 A ATOM 776 N PRO A lOl 23715 -19837 22783 10020053 A

ATOM 692 O LEU A 89 2 576 0433 6711 1 0041 03 A ATOM 777 CD PRO A lOI 22340 -20070 22305 10011370 A

ATOM 693 N SER A 90 4 272 1 434 7798 1 0047 00 A ATOM 778 CA PRO A lOl 24132 -20909 23691 10020053 A

ATOM 694 CA SER A 90 5225 0 384 17464 1 004634 A ATOM 779 CB PRO A lOl 23046-21963 23491 10011465 A

ATOM 695 CB SER A 90 5 712 0 566 16 025 1 007905 A ATOM 780 CG PRO A lOl 21831 -21125 23271 10011268 A

ATOM 696 OG SER A 90 6 704 -0 392 15 702 1 00 8327 A ATOM 781 C PRO A lOl 25534 -21446 23401 10020053 A

ATOM 697 C SER A 90 6430 0351 1 8 385 1 0044 97 A ATOM 782 O PRO A lOl 25768 -22088 22376 10020053 A

ATOM 698 O SER A 90 6 908 1 387 8 838 1 0044 79 A ATOM 783 N GLU A 102 26457-21 172 24317 10019130 A

ATOM 699 N ALA A 91 6926 -0 845 18 658 004434 A ATOM 784 CA GLU A 102 27842-21612 24198 10019130 A

ATOM 700 CA ALA A 91 8 095 -0985 19 508 1 00 42 43 A ATOM 785 CB GLU A 102 28561 -21394 25538 10014713 A

ATOM 701 CB ALA A 91 7 674 -1 180 20 955 I 00 30 60 A ATOM 786 CG GLU A 102 30004 -21885 25600 10014833 A

ATOM 702 C ALA A 91 8938 -2 162 19023 004640 A ATOM 787 CD GLU A 102 30114-23399 25683 10014964 A

ATOM 703 O ALA A 91 8445 -3 048 18 323 004827 A ATOM 788 OEl GLU A 102 29577 -23990 26648 10015045 A

ATOM 704 N ILE A 92 10214 2 154 9 392 1 0045 16 A ATOM 789 OE2 GLU A 102 30740 -23997 24782 10014876 A

ATOM 705 CA ILEA 92 11 144 -3 196 18 990 1 0045 14 A ATOM 790 C GLU A 102 27940 -23079 23770 10018786 A

ATOM 706 CB ILE A 92 12 160 -2 651 17 974 1 0055 56 A ATOM 791 O GLU A 102 28800 -23441 22965 10018492 A

ATOM 707 CG2 ILE A 92 13 040 -3 768 17478 1 0061 63 A ATOM 792 N GLY A 103 27055 -23914 24307 10014569 A

ATOM 708 CGl ILE A 92 11 423 -2 010 16 796 1 00 53 67 A ATOM 793 CA GLY A 103 27063 25329 23974 10014301 A

ATOM 709 CDl ILE A 92 12 329 -1 290 15 821 1 00 59 54 A ATOM 794 C GLY A 103 26570-26179 25130 10014088 A

ATOM 710 C ILE A 92 11 893 -3 657 20221 1 00 44 97 A ATOM 795 O GLY A 103 26309-27373 24971 10013537 A

ATOM 711 O ILE A 92 12 143 - 2 861 - 21 123 1 0046 05 A ATOM 796 N ALA A 104 26446-25557 26298 10017761 A

ATOM 712 N LYS A 93 12252 -4 936 20262 1 006776 A ATOM 797 CA ALA A 104 25979-26238 27500 10017761 A

ATOM 713 CA LYS A 93 12 985 -5474 21 403 1 00 6841 A ATOM 798 CB ALA A 104 27165-26577 28401 1009235 A

ATOM 714 CB LYS A 93 12 008 -6 066 22 418 1 00 57 46 A ATOM 799 C ALA A 104 24984-25354 28251 10017761 A

ATOM 715 CG LYS A 93 12 475 -5 970 23 853 1 00 61 15 A ATOM 800 O ALA A 104 25350-24282 28734 10017761 A

ATOM 716 CD LYS A 93 11 288 -5 984 24 821 1 00 60 92 A ATOM 801 N GLU A 105 23733-25816 28330 10016016 A

ATOM 717 CE LYS A 93 11 726 -5 743 26 281 1 00 60 82 A ATOM 802 CA GLU A 105 22630-25120 29009 10016016 A

ATOM 718 NZ LYS A 93 10 595 -5 710 27 271 1 00 63 39 A ATOM 803 CB GLU A 105 23156-24162 30088 10019622 A

ATOM 719 C LYS A 93 13967 -6 537 20926 1 0070 11 A ATOM 804 CG GLU A 105 23811-24848 31272 10019622 A

ATOM 720 O LYS A 93 13 622 -7 376 20092 1 006803 A ATOM 805 CD GLU A 105 22859 -25773 32004 10019622 A 65251/C766

ATOM 806 OElGLUA 105 22413-26771 31399 10019622 A ATOM 891 C TYRA 114 2950 -179024725 1004103 A ATOM 807 OE2GLUA105 22554-25499 33183 10019499 A ATOM 892 O TYR A 114 3934 -107224543 1004394 A ATOM 808 C GLUA 105 21694-2435428070 10016016 A ATOM 893 N LEUA 115 1772 -156424164 1003766 A ATOM 809 O GLUA 105 21083-24942 27175 10016016 A ATOM 894 CA LEU A 115 1551 045923244 1003670 A ATOM 810 N ALAA 106 21582-23045 28299 10016339 A ATOM 895 CB LEUA 115 1543 -099421806 1004107 A ATOM 811 CA ALAA 106 20733 -22144 27514 10016339 A ATOM 896 CG LEUA 115 2680 -068520828 1004432 A ATOM 812 CB ALA A 106 20711-22565 26042 1009803 A ATOM 897 CDl LEUA 115 4030 -067521529 1004270 A ATOM 813 C ALAA 106 19309-2208428062 10016339 A ATOM 898 CD2LEUA 115 2637 -1706 19711 1004762 A ATOM 814 O ALAA 106 18412-22762 27560 10016339 A ATOM 899 C LEUA 115 0208 017323560 1003914 A ATOM 815 N LYS A 107 19113 21265 29094 10012055 A ATOM 900 O LEUA 115 -0757 -0543 23828 1004167 A ATOM 816 CA LYS A 107 17806 -2109429729 10011467 A ATOM 901 N GLY A 116 0134 150323523 1004226 A ATOM 817 CB LYS A 107 17943-20286 31029 10018828 A ATOM 902 CA GLYA 116 -1128 216223806 1003660 A ATOM 818 CG LYS A 107 18523 21038 32225 10018823 A ATOM 903 C GLYA 116 -I 142 365623603 1004045 A ATOM 819 CD LYS A 107 19968-21458 32010 10018966 A ATOM 904 O GLYA 116 -0182 4331 23919 1003933 A ATOM 820 CE LYS A 107 20567-22020 33292 10018570 A ATOM 905 N GLYA 117 -2242 4172 23070 1003725 A ATOM 821 NZ LYS A 107 19752-23133 33855 10018596 A ATOM 906 CA GLY A 117 -2377 5601 22839 1004025 A ATOM 822 C LYSA 107 16817-20381 28806 10011015 A ATOM 907 C GLY A 117 -3783 597022389 1004156 A ATOM 823 O LYSA 107 17200-19842 27768 10010928 A ATOM 908 O GLYA 117 -4591 509922070 1004294 A ATOM 824 N PROA 108 15524 -20379 29174 10010202 A ATOM 909 N VALA 118 -4079 7263 22356 1003942 A ATOM 825 CD PRO A 108 14896-21146 30268 1009780 A ATOM 910 CA VALA 118 5396 773321942 1004220 A ATOM 826 CA PRO A 108 14502-19718 28360 10010076 A ATOM 911 CB VALA 118 -5867 885422880 1003182 A ATOM 827 CB PRO A 108 13222 -20430 28780 1009695 A ATOM 912 CGl VALA 118 -7199 941222421 1003322 A ATOM 828 CG PRO A 108 13455-20656 30231 1009433 A ATOM 913 CG2 VALA 118 -5974 8311 24288 I 003188 A ATOM 829 C PROA 108 14457-18225 28672 1009999 A ATOM 914 C VALA 118 -5355 823320495 1004011 A ATOM 830 O PROA 108 14923-17795 29725 1009817 A ATOM 915 O VALA 118 -4407 891620104 1004406 A ATOM 831 N TRP A 109 13910-17440 27749 1006884 A ATOM 916 N PHE A 119 6371 7886 19701 1004547 A ATOM 832 CA TRP A 109 13796-15999 27937 1006629 A ATOM 917 CA PHE A 119 -6410 8286 18291 1004678 A ATOM 833 CB TRP A 109 14799-15248 27065 1007198 A ATOM 918 CB PHEA 119 -5855 7167 17402 1003422 A ATOM 834 CG TRP A 109 14709 15572 25605 1007167 A ATOM 919 CG PHEA 119 -4417 6827 17680 1003182 A ATOM 835 CD2TRPA109 13802-15005 24644 1007068 A ATOM 920 CDl PHEA 119 -4073 5953 18711 1003001 A ATOM 836 CE2TRPA109 14098 -15593 23396 1006993 A ATOM 921 CD2 PHEA 119 -3396 7410 16934 1003050 A ATOM 837 CE3TRPA109 12771 14062 24717 1007078 A ATOM 922 CEl PHEA 119 -2727 5665 18998 1003108 A ATOM 838 CDl TRP A 109 15484-16453 24919 1006877 A ATOM 923 CE2PHEA119 -2051 7133 17207 1003131 A ATOM 839 NEl TRP A 109 15128-16471 23594 1006709 A ATOM 924 CZ PHEA 119 -1713 6258 18243 1003040 A ATOM 840 CZ2TRPA109 13400-15269 22228 1006638 A ATOM 925 C PHEA 119 -7782 8671 17765 1004769 A ATOM 841 CZ3TRPA109 12076-13740 23553 1007054 A ATOM 926 O PHEA 119 -8800 8189 18262 1004379 A ATOM 842 CH2TRPA109 12397-14344 22325 1006618 A ATOM 927 N GLN A 120 -7792 9551 16757 1003720 A ATOM 843 C TRP A 109 12393-1549427623 1006790 A ATOM 928 CA GLN A 120 -9020 10013 16102 1004057 A ATOM 844 O TRP A 109 11714-1599726720 1006951 A ATOM 929 CB GLN A 120 -8800 11377 15455 1007460 A ATOM 845 N TYRA IlO 11970 -14493 28386 1005687 A ATOM 930 CG GLN A 120 -9730 12477 15929 1007475 A ATOM 846 CA TYRAIlO 10658-13889 28212 1005551 A ATOM 931 CD GLN A 120 -11199 12111 15804 1007435 A ATOM 847 CB TYRAIlO 9801 -1409429458 1006780 A ATOM 932 OEl GLN A 120 -11615 11514 14814 1007391 A ATOM 848 CG TYRAIlO 9486-15540 29772 1007135 A ATOM 933 NE2 GLN A 120 -U 998 12486 16805 1007718 A ATOM 849 CDI TYRAIlO 10466-16401 30273 1007544 A ATOM 934 C GLN A 120 -9268 8983 15007 1003971 A ATOM 850 CEl TYRAIlO 10159-17718 30610 1007576 A ATOM 935 O GLN A 120 8412 8790 14144 1004241 A ATOM 851 CD2TYRA 110 8194 16035 29608 1007158 A ATOM 936 N LEUA 121 -10417 8313 15040 1004431 A ATOM 852 CE2TYRA110 7877-17345 29938 1007695 A ATOM 937 CA LEU A 121 -10741 7291 14035 1004597 A ATOM 853 CZ TYRAIlO 8859-18180 30441 1007724 A ATOM 938 CB LEUA 121 -10843 5930 14715 1004024 A ATOM 854 OH TYRAIlO 8533-19471 30786 1007844 A ATOM 939 CG LEU A 121 -9595 5055 14804 1003851 A ATOM 855 C TYRA 110 10831 -12401 27959 1005402 A ATOM 940 CDl LEU A 121 -8347 5893 14838 1003990 A ATOM 856 O TYRA IlO 11648-11743 28614 1005521 A ATOM 941 CD2LEUA121 -9705 4156 16024 1003400 A ATOM 857 N GLUAlIl 10062 -11881 27004 1005592 A ATOM 942 C LEU A 121 -12040 7568 13277 1004801 A ATOM 858 CA GLUAlIl 10128-10473 26654 1005394 A ATOM 943 O LEU A 121 -12964 8179 13814 1005328 A ATOM 859 CB GLUAlIl 11086 10285 25484 1008690 A ATOM 944 N GLU A 122 -12099 7112 12028 1004396 A ATOM 860 CG GLU AlIl 11970 -9071 25618 1009382 A ATOM 945 CA GLUA 122 -13281 7278 111701004550 A ATOM 861 CD GLUAlIl 12855 -9142 26844 1009879 A ATOM 946 CB GLU A 122 -12890 7462 9702 1009806 A ATOM 862 OEl GLUAlIl 13638-10109 26942 1009900 A ATOM 947 CG GLU A 122 -12028 8645 9331 10010110 A ATOM 863 OE2GLUA 111 12769 -8236 27706 10010595 A ATOM 948 CD GLU A 122 -11636 8607 7850 10010638 A ATOM 864 C GLUAlIl 8747 -993426286 1005452 A ATOM 949 OEl GLUA 122 -10951 7644 7431 10010788 A ATOM 865 O GLU A lIl 8196 -10282 25244 1005988 A ATOM 950 OE2GLUA122 -12022 9533 7103 10010647 A ATOM 866 N PROA 112 8156 -909627157 1005366 A ATOM 951 C GLU A 122 -14133 6012 11214 1004430 A ATOM 867 CD PRO A 112 8528 -889728572 1004703 A ATOM 952 O GLU A 122 -13620 4906 11406 1004549 A ATOM 868 CA PRO A 112 6832 -8518 26894 1005289 A ATOM 953 N LYS A 123 -15435 6157 11009 1005637 A ATOM 869 CB PRO A 112 6218 -844728285 1004310 A ATOM 954 CA LYSA 123 16290 4984 10975 1005722 A ATOM 870 CG PRO A 112 7389 -800729096 1004423 A ATOM 955 CB LYS A 123 -17735 5377 10701 1007203 A ATOM 871 C PROA 112 6940 -712826255 1004992 A ATOM 956 CG LYS A 123 -18631 4187 10429 1006819 A ATOM 872 O PROA 112 7948 -6443 26410 1005005 A ATOM 957 CD LYS A 123 -20044 4621 10099 1006586 A ATOM 873 N ILEA 113 5898 -672625533 1004434 A ATOM 958 CE LYS A 123 -20920 3422 97841006759 A ATOM 874 CA ILEA 113 5854 -541724900 1004631 A ATOM 959 NZ LYS A 123 -22278 3846 9353 1007160 A ATOM 875 CB ILEA 113 6202 -548623417 1004728 A ATOM 960 C LYS A 123 -15779 4122 9823 1005804 A ATOM 876 CG2ILEA 113 6081 ^tIOl 22799 1004330 A ATOM 961 O LYS A 123 -15631 4605 8701 1006280 A ATOM 877 CGl ILEA 113 7621 -6011 23228 1004434 A ATOM 962 N GLY A 124 -15482 2859 10104 1004703 A ATOM 878 CDl ILEA 113 8088 -5963 21769 1004482 A ATOM 963 CA GLY A 124 -15006 1970 9065 1004814 A ATOM 879 C ILEA 113 4451 -4845 24998 1005053 A ATOM 964 C GLY A 124 -13527 1659 9122 1004955 A ATOM 880 O ILE A 113 3489 -5491 24590 1005393 A ATOM 965 O GLY A 124 -13074 0747 84361005035 A ATOM 881 N TYRA 114 4331 -363325527 1004291 A ATOM 966 N ASP A 125 -12762 2399 9921 1004364 A ATOM 882 CA TYR A 114 3023 -299425649 10041 19 A ATOM 967 CA ASPA 125 -11320 2138 10017 1004243 A ATOM 883 CB TYR A 114 2769 -2540 27090 1003354 A ATOM 968 CB ASP A 125 -10638 3162 10935 1006370 A ATOM 884 CG TYR A 114 1358 -2068 27332 1003140 A ATOM 969 CG ASP A 125 -10581 4558 10328 1006916 A ATOM S85 CDl TYRA 114 0337 -2974 27599 1003569 A ATOM 970 ODl ASP A 125 -10876 4703 9123 1007081 A ATOM 886 CEl TYRA 114 -0978 -2541 27802 1003526 A ATOM 971 OD2ASPA125 -10231 5509 11063 1006782 A ATOM 887 CD2TYRA114 1036 -071427271 1003157 A ATOM 972 C ASPA 125 -11021 0723 10524 1004148 A ATOM 888 CE2TYRA114 -0273 -0272 27467 1003590 A ATOM 973 O ASP A 125 -11793 0150 11292 1003839 A ATOM 589 CZ TYRA 114 -1275 -119027731 1003598 A ATOM 974 N ARG A 126 -9897 0171 10083 1004791 A ATOM 890 OH TYRA 114 -2574 0757 27899 1003548 A ATOM 975 CA ARG A 126 -9482 -1167 10473 1004339 A 65251/C766

ATOM 976 CB ARGA 126 -9232 -2027 9229 1006697 A ATOM 1061 CD2TYRA136 11147-17313 19873 1008452 A ATOM 977 CG ARGA 126 -10467 -2410 8437 1006546 A ATOM 1062 CE2TYRA136 12421 -17677 19437 1008399 A ATOM 978 CD ARGA 126 10067 -3058 7115 1007038 A ATOM 1063 CZ TYRA 136 12988-17018 18355 1008529 A ATOM 979 NE ARGA 126 -11189 -3755 6496 1007393 A ATOM 1064 OH TYRA 136 14248-17357 17923 1008913 A ATOM 980 CZ ARG A 126 -11639 -4955 6877 1007716 A ATOM 1065 C TYRA 136 6852 -16505 20619 1005614 A ATOM 981 NHl ARG A 126 -12678 -5513 6257 1007683 A ATOM 1066 O TYRA 136 7063-1618621788 1005902 A ATOM 982 NH2 ARG A 126 -11039 -5612 7865 1007535 A ATOM 1067 N LEUA 137 5645 -16493 20074 1006558 A ATOM 983 C ARG A 126 -8195 -1085 11287 1004423 A ATOM 1068 CA LEUA 137 4476 -1607420825 1006229 A ATOM 984 O ARG A 126 -7214 -0489 10845 1004145 A ATOM 1069 CB LEUA 137 3272-16008 19897 1006171 A ATOM 985 N LEUA 127 -8185 -1686 12472 1004687 A ATOM 1070 CG LEUA 137 2581 -14657 19747 1005944 A ATOM 986 CA LEU A 127 -6987 -1654 13298 1004325 A ATOM 1071 CDl LEUA 137 1272-14870 19011 1006158 A ATOM 987 CB LEU A 127 -7340 -I 170 14704 1004860 A ATOM 1072 CD2LEUA137 2309-14041 21104 1006320 A ATOM 988 CG LEU A 127 -7934 0236 14740 1004758 A ATOM 1073 C LEU A 137 4130-1697822003 1006166 A ATOM 989 CDl LEU A 127 -8549 0505 16091 1004816 A ATOM 1074 O LEUA 137 3811-18153 21809 1006051 A ATOM 990 CD2LEUA127 -6852 1244 14435 1004824 A ATOM 1075 N LEU A 138 4186-16436 23222 1006922 A ATOM 991 C LEUA 127 6363 3037 13348 1004300 A ATOM 1076 CA LEUA 138 3818-1722024407 1006702 A ATOM 992 O LEUA 127 -7072 -4033 13465 1003920 A ATOM 1077 CB LEUA 138 4774-16997 25590 1005618 A ATOM 993 N SERA 128 -5039 -3090 13245 1004582 A ATOM 1078 CG LEUA 138 4220-17599 26905 1005230 A ATOM 994 CA SERA 128 -4314 -4354 13265 1004549 A ATOM 1079 CDl LEU A 138 3762-19021 26660 1005387 A ATOM 995 CB SERA 128 -3617 -4591 11928 1008930 A ATOM 1080 CD2LEUA138 5257-17575 28011 1005522 A ATOM 996 OG SERA 128 -4445 -4210 10850 1009515 A ATOM 1081 C LEUA 138 2409 -16878 24869 1007037 A ATOM 997 C SERA 128 -3252 -4340 14360 1004467 A ATOM 1082 O LEU A 138 2203 -1590925597 1006952 A ATOM 998 O SERA 128 -2601 -3321 14610 1004595 A ATOM 1083 N PHEA 139 1446 17683 24443 1004599 A ATOM 999 N ALAA 129 -3084 -5479 15016 1005508 A ATOM I0S4 CA PHEA 139 0067-1747724827 1004737 A ATOM 1000 CA ALAA 129 -2083 -5627 16060 1005605 A ATOM 1085 CB PHE A 139 -0808 -17252 23582 1006478 A ATOM 1001 CB ALAA 129 -2758 -5896 17408 1005049 A ATOM 1086 CG PHE A 139 0531 -18199 22450 1006393 A ATOM 1002 C ALA A 129 -1266 -6829 15606 1005482 A ATOM 1087 CDl PHEA 139 -0749-17798 21137 1006346 A ATOM 1003 O ALA A 129 -1675 -7975 15796 1005570 A ATOM 1088 CD2PHEA 139 -0068 -1949022690 1006654 A ATOM 1004 N GLU A 130 -0119 -6564 14990 1005727 A ATOM 1089 CEl PHEA 139 -0510-1866620079 1006810 A ATOM 1005 CA GLUA 130 0721 -7632 14468 1005824 A ATOM 1090 CE2PHEA139 0174-2036721641 1006408 A ATOM 1006 CB GLUA 130 0821 -7479 12952 10011053 A ATOM 1091 CZ PHE A 139 -0047 -19956 20330 1006802 A ATOM 1007 CG GLUA 130 -0533 -7522 12263 10011007 A ATOM 1092 C PHEA 139 -0400-1868725628 1005140 A ATOM 1008 CD GLUA 130 -0527 -6873 10888 10011556 A ATOM 1093 O PHEA 139 -1542-1914025506 1005150 A ATOM 1009 OEl GLU A 130 -1580 -6917 10213 10011693 A ATOM 1094 N ALA A 140 0498-19195 26466 1006581 A ATOM 1010 OE2GLUA130 0518 6314 10482 10011537 A ATOM 1095 CA ALAA 140 0211-20361 27284 1006711 A ATOM 1011 C GLU A 130 2117 -7731 15079 1005463 A ATOM 1096 CB ALA A 140 1509-2102627716 1005315 A ATOM 1012 O GLUA 130 2598 -6804 15725 1005455 A ATOM 1097 C ALA A 140 -0620 -2004028509 1006750 A ATOM 1013 N ILEA 131 2748 -8886 14887 1005518 A ATOM 1098 O ALA A 140 -1572 -2075228817 1006939 A ATOM 1014 CA ILE A 131 4104 -9136 15368 1005772 A ATOM 1099 N GLU A 141 -0258-18972 29211 1008280 A ATOM 1015 CB ILEA 131 4129-10116 16541 1005977 A ATOM 1100 CA GLUA 141 -0969 -1860430423 1008598 A ATOM 1016 CG2ILEA131 3477 -9477 17758 1006000 A ATOM 1101 CB GLUA 141 0169 -17575 31228 10020084 A ATOM 1017 CGl ILE A 131 3441 -11421 16130 1005596 A ATOM 1102 CG GLUA 141 -0780-17237 32588 10020084 A ATOM 1018 CDl ILEA 131 3482-12491 17194 1005457 A ATOM 1103 CD GLUA 141 -1850-16155 32519 10020084 A ATOM 1019 C ILEA 131 4866 -9761 14216 1005961 A ATOM 1104 OEl GLUA 141 -2727 -16126 33408 10020084 A ATOM 1020 O ILEA 131 4254-10268 13278 1006033 A ATOM 1105 OE2GLUA 141 -1809 15324 31588 10020084 A ATOM 1021 N ASN A 132 6191 -9740 14290 1006324 A ATOM 1106 C GLU A 141 -2376-1808930185 1008808 A ATOM 1022 CA ASN A 132 7015-10295 13223 1006024 A ATOM 1107 O GLU A 141 -3332-18846 30319 1009176 A ATOM 1023 CB ASNA 132 8245 -9422 13027 1005469 A ATOM 1108 N SERA 142 -2522-16818 29825 1008198 A ATOM 1024 CG ASNA 132 9167 -9468 14210 1005339 A ATOM 1109 CA SER A 142 -3862-16277 29637 1008497 A ATOM 1025 ODl ASN A 132 8725 -9449 15359 1005508 A ATOM 1110 CB SERA 142 -4657 -16482 30920 1004982 A ATOM 1026 ND2ASNA132 10462 -9524 13943 1005122 A ATOM 1111 OG SER A 142 -6033-16316 30690 1005070 A ATOM 1027 C ASNA 132 7452-11744 13456 1005789 A ATOM 1112 C SERA 142 -3900-14795 29261 1008629 A ATOM 1028 O ASN A 132 7698-12473 12495 1006106 A ATOM 1113 O SERA 142 -4101-1443428095 1009138 A ATOM 1029 N ARG A 133 7551-12164 14718 1005681 A ATOM 1114 N GLY A 143 -3735-13931 30254 1005311 A ATOM 1030 CA ARGA 133 7967-13535 15030 1005240 A ATOM 1115 CA GLY A 143 -3756-12511 29960 1005058 A ATOM 1031 CB ARGA 133 9280-13518 15821 1007103 A ATOM 1116 C GLY A 143 -2387 -1200629535 1004865 A ATOM 1032 CG ARGA 133 10450-12904 15073 1007361 A ATOM 1117 O GLYA 143 -1985-10912 29925 1005064 A ATOM 1033 CD ARGA 133 10704-13621 13752 1007885 A ATOM 1118 N GLN A 144 -1678-1280028731 1005041 A ATOM 1034 NE ARGA 133 10997-15043 13935 1007671 A ATOM 1119 CA GLN A 144 -0339 -1245728263 1004494 A ATOM 1035 CZ ARGA 133 12131-15520 14440 1007781 A ATOM 1120 CB GLN A 144 0539 -13704 28228 1006083 A ATOM 1036 NHl ARG A 133 12305-16828 14571 1008049 A ATOM 1121 CG GLN A 144 0483-1453729493 1006011 A ATOM 1037 NH2ARGA133 13097-14691 14805 1007710 A ATOM 1122 CD GLN A 144 1480-1567729484 1006008 A ATOM 1038 C ARG A 133 6920-14338 15803 1005699 A ATOM 1123 OEl GLN A 144 1593 -16422 28507 1006565 A ATOM 1039 O ARG A 133 7143-14701 16954 1005935 A ATOM 1124 NE2GLNA 144 2206 15825 30583 1005862 A ATOM 1040 N PRO A 134 5771-14647 15170 1004815 A ATOM 1125 C GLNA 144 -0334 -11822 26885 1004674 A ATOM 1041 CD PRO A 134 5451 -14444 13745 1004046 A ATOM 1126 O GLN A 144 0606-11132 26518 1004905 A ATOM 1042 CA PRO A 134 4704-15414 15827 I 005187 A ATOM 1127 N VALA 145 -1379-12061 26114 1004036 A ATOM 1043 CB PRO A 134 3644-15542 14738 1004318 A ATOM 1128 CA VALA 145 -1463-11502 24782 1003861 A ATOM 1044 CG PRO A 134 4459-15556 13486 1004518 A ATOM 1129 CB VAL A 145 -1133-1256923726 1003242 A ATOM 1045 C PROA 134 5157-16767 16341 1005705 A ATOM 1130 CGl VALA 145 -1186-1196422330 1003058 A ATOM 1046 O PROA 134 4445-17412 17091 1006009 A ATOM 1131 CG2 VALA 145 0238-1313423985 1002950 A ATOM 1047 N ASPA 135 6343-17199 15938 1007314 A ATOM 1132 C VALA 145 -2874 -10979 24546 1003972 A ATOM 1048 CA ASP A 135 6858 18479 16395 1006960 A ATOM 1133 O VALA 145 -3824 -1175424513 1004240 A ATOM 1049 CB ASP A 135 7953-18973 15443 10011753 A ATOM 1134 N TYRA 146 -3010 -9665 24386 1004862 A ATOM 1050 CG ASP A 135 8905-17873 15028 10011700 A ATOM 1135 CA TYR A 146 -4310 -905624152 1004683 A ATOM 1051 ODl ASPA 135 9747-17473 15857 10011294 A ATOM 1136 CB TYR A 146 -4995 -8703 25479 1004262 A ATOM 1052 OD2ASPA135 8806-17403 13873 10011858 A ATOM 1137 CG TYR A 146 -4125 -7951 26456 1004265 A ATOM 1053 C ASP A 135 7379-18389 17832 1006831 A ATOM 1138 CDl TYRA 146 -3255 -8629 27309 1004204 A ATOM 1054 O ASP A 135 7635-19413 18469 1007500 A ATOM 1139 CEl TYRA 146 -2407 -793828180 1004083 A ATOM 1055 N TYRA 136 7519-17165 18344 1005302 A ATOM 1140 CD2TYRA 146 -4134 -6556 26498 1003824 A ATOM 1056 CA TYR A 136 7993-16945 19712 1005423 A ATOM 1141 CE2 TYR A 146 -3292 -584927363 1004029 A ATOM 1057 CB TYRA 136 9078-15869 19748 1008274 A ATOM 1142 CZ TYR A 146 -2426 -6546 28205 1004033 A ATOM 1058 CG TYR A 136 10433-16299 19241 1008235 A ATOM 1143 OH TYRA 146 -1575 -587029065 1004131 A ATOM 1059 CDlTYRA 136 11023-15657 18154 1008195 A ATOM 1144 C TYRA 146 -4223 -7816 23269 1004514 A ATOM 1060 CEl TYRA 136 12296-16009 17709 1008450 A ATOM 1145 O TYRA 146 -3148 -7255 23041 1004331 A 65251/C766

ATOM 1146 N PHE A 147 -5385 -738722797 1004060 A ATOM 1231 OH TYRA 157 -16271 -30162 34968 1003118 A ATOM 1147 CA PHEA 147 -5513 -626021895 1004012 A ATOM 1232 C TYRA 157 -23779 -32372 33666 1004086 A ATOM 1148 CB PHEA 147 -5324 -6785 20471 1004579 A ATOM 1233 O TYRA 157 -24696-31555 33525 1004086 A ATOM 1149 CG PHEA 147 -5648 -5799 19384 1004484 A ATOM 1234 N ASN A 158 -24003-3363434001 1004005 A ATOM 1150 CDl PHE A 147 -5364 -4445 19526 1004533 A ATOM 1235 CA ASNA 158 -25357-34150 34193 1004005 A ATOM 1151 CD2PHEA147 -6188 6248 18176 1004717 A ATOM 1236 CB ASNA 158 -25697-35122 33038 1004110 A ATOM 1152 CEl PHEA 147 -5613 -3554 18479 1004566 A ATOM 1237 CG ASNA 158 -27106-35709 33120 1005180 A ATOM 1153 CE2PHEA147 -6439 -5366 17127 1004574 A ATOM 1238 ODl ASN A 158 -27855 -35469 34072 1005180 A ATOM 1154 CZ PHEA 147 -6150 -4018 17279 1004658 A ATOM 1239 ND2ASNA158 -27447 -3649732098 1005180 A ATOM 1155 C PHE A 147 -6919 -5715 22109 1004166 A ATOM 1240 C ASN A 158 -25448 -34862 35535 1004005 A ATOM 1156 O PHE A 147 -7890 -6461 22051 1003914 A ATOM 1241 O ASN A 158 -24784 -35869 35749 1004005 A ATOM 1157 N GLYA 148 -7029 -4417 22378 1003016 A ATOM 1242 N TYRA 159 -26241 -34318 36447 1003938 A ATOM 1158 CA GLY A 148 -8333 -3832 22609 1003464 A ATOM 1243 CA TYRA 159 26447 34947 37741 1003938 A ATOM 1159 C GLYA14S -8434 -235022308 1003686 A ATOM 1244 CB TYRA 159 -26331-33946 38888 1003413 A ATOM 1160 O GLYA 148 -7439 -167022070 1003947 A ATOM 1245 CG TYRA 159 -24985 -33308 39068 1003769 A ATOM 1161 N ILEA 149 9666 -1859 22301 1005038 A ATOM 1246 CDl TYRA 159 -24611 -32205 38310 1003769 A ATOM 1162 CA ILE A 149 -9942 -046022054 1004879 A ATOM 1247 CElTYRA 159 -23402 -31554 38534 1003769 A ATOM 1163 CB ILE A 149 -10090 -014020552 1005812 A ATOM 1248 CD2TYRA159 -24110-33758 40051 1003769 A ATOM 1164 CG2ILEA 149 -8908 -0683 19770 1005867 A ATOM 1249 CE2TYRA159 -22900-33121 40280 1003769 A ATOM 1165 CGl ILEA 149 -11368 -075720005 1005416 A ATOM 1250 CZ TYRA 159 -22552-32009 39517 1003769 A ATOM 1166 CDl ILEA 149 -11642 -0329 18594 1005741 A ATOM 1251 OH TYRA 159 -21372 -31328 39750 1003769 A ATOM 1167 C ILE A 149 11242 0101 22749 1005083 A ATOM 1252 C TYR A 159 -27875-35481 37733 1003938 A ATOM 1168 O ILEA 149 ■12148 -092722875 1005600 A ATOM 1253 O TYRA 159 -28807-34739 37416 1003938 A ATOM 1169 N ILEA 150 -11324 1141 23199 1003872 A ATOM 1254 N THR A 160 -28062 -36748 38092 1004226 A ATOM 1170 CA ILE A 150 -12503 1642 23884 1003923 A ATOM 1255 CA THRA 160 -29407-37292 38099 1004226 A ATOM 1171 CB ILEA 150 -12268 1652 25423 1004384 A ATOM 1256 CB THRA 160 -29683 -38044 36794 1004860 A ATOM 1172 CG2ILEA150 -11007 2412 25753 1004714 A ATOM 1257 OGl THR A 160 -29364 -37201 35678 1003594 A ATOM 1173 CGl ILE A 150 -13453 2281 26151 1004183 A ATOM 1258 CG2THRA160 -31147-38445 36715 1003594 A ATOM 1174 CDl ILEA 150 -14672 1425 26166 1003984 A ATOM 1259 C THRA 160 -29753-38229 39251 1004226 A ATOM 1175 C ILE A 150 12738 3062 23366 1004057 A ATOM 1260 O THR A 160 -29045 -39208 39489 1004226 A ATOM 1176 O ILEA 150 •11803 384023213 1003968 A ATOM 1261 N VALA 161 -30827 -37925 39979 1004105 A ATOM 1177 N ALA A 151 -13983 3391 23068 1004822 A ATOM 1262 CA VALA 161 31278-38833 41028 1004105 A ATOM 1178 CA ALAA 151 14301 4722 22579 1004696 A ATOM 1263 CB VALA 161 -31457-3813742395 1005989 A ATOM 1179 CB ALAA 151 -15619 4693 21829 1002138 A ATOM 1264 CGl VAL A 161 -30231 -37332 42710 1004440 A ATOM 1180 C ALAA 151 -14384 5701 23750 1004792 A ATOM 1265 CG2 VAL A 161 32682-37281 42395 1004440 A ATOM 1181 O ALAA 151 -15133 549024704 1005030 A ATOM 1266 C VALA 161 -32621 -39416 40530 1004105 A ATOM 1182 N LEU A 152 -13609 6773 23683 1007922 A ATOM 1267 O VALA 161 -33454-38706 39951 1004105 A ATOM 1183 CA LEUA 152 -13617 7762 24745 1008320 A ATOM 1268 N THR A 162 -32812-40714 40735 1007123 A ATOM 1184 CB LEUA 152 -12190 813425120 1005100 A ATOM 1269 CA THR A 162 -34030 -4138440298 1007123 A ATOM 1185 CG LEUA 152 -11364 6972 25648 1005225 A ATOM 1270 CB THR A 162 -33717 -42364 39187 1008469 A ATOM 1186 CDl LEUA 152 -9960 7442 25932 1004994 A ATOM 1271 OGl THRA 162 -32661 ^tI 835 38381 1005602 A ATOM 1187 CD2 LEUA 152 -11996 642426897 1005145 A ATOM 1272 CG2 THRA 162 -34929-42570 38315 1005602 A ATOM 1188 C LEU A 152 -14376 900424319 1008605 A ATOM 1273 C THRA 162 -34680-42161 41428 1007123 A ATOM 1189 O LEUA 152 15459 927624829 1009191 A ATOM 1274 O THRA 162 -33985-42671 42309 1007123 A ATOM 1190 N ILE A 153 ■16557-27053 20409 1004914 A ATOM 1275 N LEU A 163 -36006-4225941410 10011354 A ATOM 1191 CA ILE A 153 -16360-27912 21567 1004914 A ATOM 1276 CA LEU A 163 -36704-42997 42449 10011354 A ATOM 1192 CB ILEA 153 -15011 -27653 22245 1004426 A ATOM 1277 CB LEU A 163 -38174 -4260042516 10012552 A ATOM 1193 CG2ILEA153 -13889-2812021346 1004104 A ATOM 1278 CG LEU A 163 -38622-4212443901 1007361 A ATOM 1194 CGl ILEA 153 -14869-26171 22579 1004104 A ATOM 1279 CDl LEUA 163 -40124 -41947 43914 1007361 A ATOM 1195 CDl ILE A 153 -13557-25831 23273 1004104 A ATOM 1280 CD2LEUA 163 -38208-4312944966 1007361 A ATOM 1196 C ILEA 153 ■ 17461 -2774722602 1004914 A ATOM 1281 C LEUA 163 -36593-44482 42167 10011354 A ATOM 1197 O ILE A 153 ■18145-2671922663 1004914 A ATOM 1282 O LEUA 163 -36981-4530642994 10011354 A ATOM 1198 N THRA 154 -17606-2877623430 1005113 A ATOM 1283 N LYS A 164 -36054 -44822 41000 1006617 A ATOM 1199 CA THRA 154 -18647-28813 24436 1005113 A ATOM 1284 CA LYS A 164 -35889 46223 40618 1006617 A ATOM 1200 CB THRA 154 -19852 -2959423872 1003742 A ATOM 1285 CB LYS A 164 -34755 -46875 41412 1007117 A ATOM 1201 OGl THR A 154 -20865 -28662 23499 1004770 A ATOM 1286 CG LYS A 164 -33462 -47041 40638 1007092 A ATOM 1202 CG2THRA154 -20405-30608 24881 1004770 A ATOM 1287 CD LYS A 164 -33666 -47946 39444 1007092 A ATOM 1203 C THRA 154 -18233 -29432 25756 1005113 A ATOM 1288 CE LYS A 164 -32382-48151 38653 1007092 A ATOM 1204 O THR A 154 -17443-30374 25789 1005113 A ATOM 1289 NZ LYS A 164 -32558^)9127 37521 1007092 A ATOM 1205 N LEUA 155 -18761 -28881 26844 1003435 A ATOM 1290 C LYS A 164 -37188-46951 40906 1006617 A ATOM 1206 CA LEUA 155 -18521 -29438 28173 1003435 A ATOM 1291 O LYSA 164 -38226 -4631241066 1006617 A ATOM 1207 CB LEUA 155 -17575 -28558 28990 1004053 A ATOM 1292 N ASP A 165 -37146 -4827740967 10017988 A ATOM 1208 CG LEU A 155 -17198-2917030358 1003711 A ATOM 1293 CA ASP A 165 -38352-4903741260 10017988 A ATOM 1209 CDl LEUA 155 -16612-30562 30189 1003711 A ATOM 1294 CB ASP A 165 -38063 -5054041222 10014562 A ATOM 1210 CD2 LEUA 155 -16180-28287 31054 1003711 A ATOM 1295 CG ASPA 165 -36834 -50925 42033 10014562 A ATOM 1211 C LEUA 155 19889-29562 28876 1003435 A ATOM 1296 ODl ASP A 165 -36852 -50765 43275 10014562 A ATOM 1212 O LEUA 155 -20557 -28559 29127 1003435 A ATOM 1297 OD2ASPA165 -35844 -51388 41422 10014562 A ATOM 1213 N LYSA 156 -20316 -3078729172 1004195 A ATOM 1298 C ASP A 165 -38825 -4861642643 I 0017988 A ATOM 1214 CA LYS A 156 -21614-30986 29812 1004195 A ATOM 1299 O ASP A 165 -38874 -4742642953 10017988 A ATOM 1215 CB LYS A 156 -22576-3167428832 1003822 A ATOM 1300 N ASP A 166 -39168-49573 43488 10010017 A ATOM 1216 CG LYS A 156 -23979-31822 29379 1004041 A ATOM 1301 CA ASFA 166 -39617 -49189 44809 10010017 A ATOM 1217 CD LYS A 156 -24940-32481 28397 1004041 A ATOM 1302 CB ASPA 166 -40729-50125 45274 10018127 A ATOM 1218 CE LYS A 156 -24666 -33963 28205 1004041 A ATOM 1303 CG ASPA 166 41979 -4998044433 10018127 A ATOM 1219 NZ LYS A 156 -25714 -3462827362 1004041 A ATOM 1304 ODl ASP A 166 -41898-50221 43209 10018127 ATOM 1220 C LYS A 156 -21555-31791 31110 1004195 A A ATOM 1221 O LYS A 156 -20905 -32829 31164 1004195 A ATOM 1305 OD2 ASP A 166 -43035 -49613 44990 10018127 ATOM 1222 N TYRA 157 -22229 -31293 32146 1004086 A A ATOM 1223 CA TYRA 157 -22319-31954 33450 1004086 A ATOM 1306 C ASP A 166 -38477 -49148 45802 10010017 A ATOM 1224 CB TYRA 157 -21890-31002 34562 1004884 A ATOM 1307 O ASP A 166 -37804 -50163 46033 10010017 A ATOM 1225 CG TYRA 157 -20395-30800 34680 1003118 A ATOM 1308 N GLYA 167 -38247 -47958 46365 10015167 A ATOM 1226 CDlTYRA 157 -19517-3133433736 1003118 A ATOM 1309 CA GLY A 167 -37192 -4780847347 10015167 A ATOM 1227 CEl TYRA 157 18132 31134 33831 1003118 A ATOM 1310 C GLYA 167 -36376-4657747476 10015167 A ATOM 1228 CD2TYRA157 19852-30058 35729 1003118 A ATOM 1311 O GLYA 167 -36861 -45467 47697 10015167 A ATOM 1229 CE2TYRA 157 -18472-29847 35831 1003118 A ATOM 1312 N LEU A 168 -35089-46835 47336 10012130 A ATOM 1230 CZ TYRA 157 -17624-30386 34879 10031 18 A ATOM 1313 CA LEU A 168 -34063 4583447440 10012130 A 65251/C766

ATOM 1314 CB LEUA 16S -32721 -46539 47621 10014736 A ATOM 1399 CE2TYRA177 -12788 -31975 24093 1005143 A ATOM 1315 CG LEUA 168 -32829 -47874 48370 10014736 A ATOM 1400 CZ TYRA 177 -12895-3061624336 1005143 A ATOM 1316 CDl LEUA 168 -31484-48570 48362 10014736 A ATOM 1401 OH TYRA 177 -12293-29725 23483 1005143 A ATOM 1317 CD2 LEUA 168 -33319-47644 49799 10014736 A ATOM 1402 C TYRA 177 -16709-33715 25302 1002971 A ATOM 1318 C LEU A 168 -34031-44936 46210 10012130 A ATOM 1403 O TYRA 177 -16291 -34779 24846 1002971 A ATOM 1319 O LEUA 168 -34729 -45170 45223 10012130 A ATOM 1404 N ASN A 178 -17475 -3288824590 1004137 A ATOM 1320 N TYR A 169 -33209 -43898 46295 10061 11 A ATOM 1405 CA ASNA 178 -17925 -33257 23243 1004137 A ATOM 1321 CA TYRA 169 -33044-42951 45217 10061 11 A ATOM 1406 CB ASNA 178 -16757 -3358022309 1006053 A ATOM 1322 CB TYRA 169 -33167 -41524 45736 1006698 A ATOM 1407 CG ASNA 178 -16034 -3234321836 1005300 A ATOM 1323 CG TYRA 169 -34545 -41 127 46175 1006698 A ATOM 1408 ODl ASN A 178 -16505 -31225 22029 1005300 A ATOM 1324 CDl TYRA 169 -35069 -41557 47390 1006698 A ATOM 1409 ND2ASNA178 -14886 -32535 21196 1005300 A ATOM 1325 CEl TYRA 169 -36348 41 184 47784 1006698 A ATOM 1410 C ASN A 178 -18740-34513 23505 1004137 A ATOM 1326 CD2 TYRA 169 -35331 -40314 45367 1006698 A ATOM 1411 O ASN A 178 -19531-34538 24443 1004137 A ATOM 1327 CE2TYRA169 -36607 -39936 45748 I 006698 A ATOM 1412 N ASPA 179 -18549 -35554 22704 1005217 A ATOM 1328 CZ TYRA 169 -37111 -40374 46954 1006698 A ATOM 1413 CA ASPA 179 -19282 -36793 22939 1005217 A ATOM 1329 OH TYRA 169 -38382 40016 47321 1006698 A ATOM 1414 CB ASP A 179 -19751 3742621616 1004620 A ATOM 1330 C TYRA 169 -31648-43151 44677 I 0061 11 A ATOM 1415 CG ASP A 179 -18616-3765920623 1005015 A ATOM 1331 O TYRA 169 -30665-43038 45414 10061 11 A ATOM 1416 ODl ASPA 179 -17433 -37384 20957 1005015 A ATOM 1332 N ASP A 170 -31551 -43456 43392 1 003880 A ATOM 1417 OD2ASPA179 -18914-38127 19494 1005015 A ATOM 1333 CA ASPA 170 -30241 -43637 42778 1003880 A ATOM 1418 C ASPA 179 -18436-37791 23729 1005217 A ATOM 1334 CB ASPA 170 -30296 -44607 41609 1009231 A ATOM 1419 O ASPA 179 -18780-38965 23802 1005217 A ATOM 1335 CG ASPA 170 -29999 -46026 42027 1009231 A ATOM 1420 N GLN A 180 -17346-3731724334 1004783 A ATOM 1336 ODl ASP A 170 -29126-46212 42907 1009231 A ATOM 1421 CA GLN A 180 -16439-38178 25099 1004783 A ATOM 1337 OD2ASPA170 -30626 -46952 41469 1009231 A ATOM 1422 CB GLN A 180 -14994-37723 24910 1004930 A ATOM 1338 C ASPA 170 29673 -42324 42295 1003880 A ATOM 1423 CG GLNA 180 -14553 -3760923491 1004093 A ATOM 1339 O ASP A 170 -30410-41401 41990 I 003880 A ATOM 1424 CD GLN A 180 -14656-38915 22753 1004093 A ATOM 1340 N GLY A 171 -28353 -42239 42229 1004191 A ATOM 1425 OEl GLN A 180 -15597-39135 21981 1004093 A ATOM 1341 CA GLYA 171 27731 -41013 41781 1004191 A ATOM 1426 NE2GLN A 180 -13686 -3980222984 1004093 A ATOM 1342 C GLY A 171 -26556 -41274 40857 1004191 A ATOM 1427 C GLN A 180 -16702-3823726611 1004783 A ATOM 1343 O GLY A 171 -25732-42149 41090 1004191 A ATOM 1428 O GLN A 180 -16590 37231 27314 1004783 A ATOM 1344 N VALA 172 -26490-40516 39779 1004138 A ATOM 1429 N LEUA 181 -17023-39418 27127 1004538 A ATOM 1345 CA VALA 172 -25393-40633 38835 1004138 A ATOM 1430 CA LEUA 181 -17257-39533 28551 1004538 A ATOM 1346 CB VALA 172 -25754 -41408 37558 1 006065 A ATOM 1431 CB LEUA 181 -17780^10925 28891 1004735 A ATOM 1347 CGl VAL A 172 -25589 -42883 37789 1005266 A ATOM 1432 CG LEUA 181 -17920-41175 30391 1003478 A ATOM 1348 CG2VALA172 -27171 -41074 37131 1005266 A ATOM 1433 CDl LEUA 181 18922 ^O 177 30981 1003478 A ATOM 1349 C VALA 172 -24986-39262 38381 1004138 A ATOM 1434 CD2LEUA 181 -18348-42622 30638 1003478 A ATOM 1350 O VAL A 172 -25759-38296 38436 1004138 A ATOM 1435 C LEUA 181 -15931 39268 29272 1004538 A ATOM 1351 N PHE A 173 -23752 -39197 37916 1002987 A ATOM 1436 O LEUA 181 -14900 -39824 28923 1004538 A ATOM 1352 CA PHEA 173 -23192-37973 37403 1002987 A ATOM 1437 N VAL A 182 -15955-3840730273 1004281 A ATOM 1353 CB PHEA 173 -22312 -37306 38439 1005502 A ATOM 1438 CA VAL A 182 -14746-38101 31015 1004281 A ATOM 1354 CG PHEA 173 -21479-36218 37866 1003684 A ATOM 1439 CB VALA 182 -14536-36591 31113 1005581 A ATOM 1355 CDl PHE A 173 -22043 -34980 37574 1003684 A ATOM 1440 CGl VAL A 182 -13294-36288 31928 1003429 A ATOM 1356 CD2PHEA 173 -20143 36450 37535 1003684 A ATOM 1441 CG2VALA182 -14416-36003 29737 1003429 A ATOM 1357 CEl PHEA 173 -21292 -33991 36956 1003684 A ATOM 1442 C VALA 182 -14803-38664 32434 1004281 A ATOM 1358 CE2PHEA 173 -19381-35472 36919 I 003684 A ATOM 1443 O VAL A 182 -13800-39152 32955 1004281 A ATOM 1359 CZ PHE A 173 -19956-34238 36626 1003684 A ATOM 1444 N THRA 183 -15978 38591 33056 1004868 A ATOM 1360 C PHEA 173 22344 38307 36188 1002987 A ATOM 1445 CA THRA 183 -16154-39080 34412 1004868 A ATOM 1361 O PHEA 173 -21588-39276 36192 1002987 A ATOM 1446 CB THR A 183 -15894 -3797635423 1005065 A ATOM 1362 N TYRA 174 -22473 -37504 35141 1005399 A ATOM 1447 OGl THRA 183 -14518-37615 35383 1003724 A ATOM 1363 CA TYRA 174 21688-37717 33936 1005399 A ATOM 1448 CG2THRA 183 -16239-38424 36811 1003724 A ATOM 1364 CB TYRA 174 -22558 -38194 32765 1006063 A ATOM 1449 C THRA 183 -17554-39571 34677 1004868 A ATOM 1365 CG TYRA 174 -23152-39571 32932 1004667 A ATOM 1450 O THRA 183 -18523-38958 34231 1004868 A ATOM 1366 CDl TYR A 174 -24503 -39734 33244 1004667 A ATOM 1451 N LYS A 184 -17657-40683 35399 1004166 A ATOM 1367 CElTYRA 174 -25057 ^l 001 33403 1004667 A ATOM 1452 CA LYS A 184 -18953-41201 35792 1004166 A ATOM 1368 CD2TYRA174 -22365 -40717 32786 1004667 A ATOM 1453 CB LYS A 184 -19290 -42526 35129 1005457 A ATOM 1369 CE2TYRA174 -22909 -41991 32946 1004667 A ATOM 1454 CG LYS A 184 -20627^3062 35613 1004641 A ATOM 1370 CZ TYRA 174 -24257 ^2125 33251 1004667 A ATOM 1455 CD LYS A 184 -20956^14422 35042 1004641 A ATOM 1371 OH TYRA 174 24821 -43379 33377 1004667 A ATOM 1456 CE LYS A 184 -22265-44931 35601 1004641 A ATOM 1372 C TYRA 174 -21011-36425 33537 1005399 A ATOM 1457 NZ LYS A 184 -22547-4632235153 1004641 A ATOM 1373 O TYRA 174 -21612-35359 33582 1005399 A ATOM 1458 C LYSA 184 -18873-41418 37280 1004166 A ATOM 1374 N ASPA 175 -19745-36538 33 157 I 005186 A ATOM 1459 O LYSA 184 -17884-41958 37784 1004166 A ATOM 1375 CA ASP A 175 -18944-35414 32688 10051 86 A ATOM 1460 N ILEA 185 -19906-40974 37983 1004772 A ATOM 1376 CB ASP A 175 -17659-35317 33499 1007421 A ATOM 1461 CA ILEA 185 -19974-41 131 39423 1004772 A ATOM 1377 CG ASP A 175 -16833-34101 33136 1006242 A ATOM 1462 CB ILEA 185 -19677-3980240141 1005821 A ATOM 1378 ODlASPA 175 -16876 -33675 31968 1006242 A ATOM 1463 CG2ILEA185 -20036-3991941637 1002713 A ATOM 1379 OD2ASPA175 16120 33574 34012 1006242 A ATOM 1464 CGl ILEA 185 -18203 39429 39950 1002713 A ATOM 1380 C ASP A 175 -18607-35739 31224 1005186 A ATOM 1465 CDl ILEA 185 -17864 -38032 40457 1002713 A ATOM 1381 O ASPA 175 -17884-36696 30941 1005186 A ATOM 1466 C ILEA 185 21370 -41602 39792 1004772 A ATOM 1382 N HIS A 176 -19138-34958 30292 1004663 A ATOM 1467 O ILEA 185 •22359-41152 39212 1004772 A ATOM 1383 CA HIS A 176 -18880 -35199 28873 1004663 A ATOM 1468 N SERA 186 -21455 -42530 40737 1004736 A ATOM 1384 CB HISA 176 -20183-35482 28134 1007151 A ATOM 1469 CA SERA 186 -22753 -4302741175 1004736 A ATOM 1385 CG HIS A 176 -20746 -36839 28388 1004064 A ATOM 1470 CB SERA 186 -23070 -44358 40505 1007566 A ATOM 1386 CD2HISA176 -21840 -37234 29080 1004064 A ATOM 1471 OG SERA 186 -21949 -45203 40547 1006477 A ATOM 1387 NDl HIS A 176 -20196 -37982 27854 1004064 A ATOM 1472 C SER A 186 -22787-43151 42689 1004736 A ATOM 1388 CEl HIS A 176 -20928 -39023 28201 1004064 A ATOM 1473 O SERA 186 -21753 -43337 43334 1004736 A ATOM 1389 NE2HIS A 176 -21932 -38596 28944 1004064 A ATOM 1474 N TYRA 187 -23984 -43011 43247 1004869 A ATOM 1390 C HIS A 176 -18198-34034 28171 1004663 A ATOM 1475 CA TYR A 187 -24179 -4306744680 1004869 A ATOM 1391 O HIS A 176 -18676-32893 28221 1004663 A ATOM 1476 CB TYR A 187 -25521 -4244845036 1009367 A ATOM 1392 N TYRA 177 -17070 34316 27528 1002971 A ATOM 1477 CG TYRA 187 -25736-4233746511 1004788 A ATOM 1393 CA TYRA 177 -16357-33308 26736 1002971 A ATOM 1478 CDl TYRA 187 -25018-4142047267 1004788 A ATOM 1394 CB TYR A 177 -14858-33406 26936 1005842 A ATOM 1479 CEl TYR A 187 -25219-41311 48640 1004788 A ATOM 1395 CG TYRA 177 -14133 -32440 26058 1005143 A ATOM 1480 CD2TYRA 187 -26664-4315247164 1004788 A ATOM 1396 CDlTYRA 177 -14222-31066 26282 1005143 A ATOM 1481 CE2 TYRA 187 -26876 -43049 48543 1004788 A ATOM 1397 CEl TYRA 177 -13607-30153 25425 1005143 A ATOM 1482 CZ TYRA 187 -26152-4212749271 1004788 A ATOM 1398 CD2TYRA177 13408-32882 24957 1005143 A ATOM 1483 OH TYRA 187 -26359-42014 50628 1004788 A 65251/C766

ATOM 1484 C TYRA 187 -24129 -44493 45187 1004869 A ATOM 1569 CA PHEA 198 15112-44183 35204 1004442 A ATOM 1485 O TYRA 187 -24918 -45324 44759 1004869 A ATOM 1570 CB PHEA 198 -16050-44255 34006 1005273 A ATOM 1486 N ASNA 188 -23190-44768 46092 1004673 A ATOM 1571 CG PHEA 198 -15351-44153 32693 1005273 A ATOM 1487 CA ASNA 188 -2301946085 46692 1004673 A ATOM 1572 CDl PHEA 198 14923 -45294 32034 I 005273 A ATOM 1488 CB ASNA 188 -21579 -46233 47140 10018297 A ATOM 1573 CD2PHEA198 -15087-42908 32121 1005273 A ATOM 1489 CG ASNA 188 -21313-47566 47734 1004400 A ATOM 1574 CEl PHEA 198 -1424145200 30823 1005273 A ATOM 1490 ODl ASN A 188 -22009 -4799648642 1004400 A ATOM 1575 CE2PHEA198 14403-42801 30912 1005273 A ATOM 1491 ND2ASNA188 -20296 -48239 47232 1004400 A ATOM 1576 CZ PHE A 198 -13981 -43952 30263 1005273 A ATOM 1492 C ASN A 188 -23949-46212 47908 1004673 A ATOM 1577 C PHEA 198 -14359-42876 35155 1004442 A ATOM 1493 O ASN A 188 -2374445536 48923 1004673 A ATOM 1578 O PHEA 198 -14824 -41835 35637 I 004442 A ATOM 1494 N HIS A 189 .24959 -47073 47821 1006284 A ATOM 1579 N ARG A 199 -13183-42936 34557 1005101 A ATOM 1495 CA HIS A 189 -25911 -47240 48920 1006284 A ATOM 1580 CA ARGA 199 -12357-41754 34370 1005101 A ATOM 1496 CB HIS A 189 -27110 4802048435 10010985 A ATOM 1581 CB ARGA 199 -11392-41567 35524 1006313 A ATOM 1497 CG HIS A 189 -27984 -47233 47520 1007039 A ATOM 1582 CG ARGA 199 -10504 -40367 35300 1006313 A ATOM 1498 CD2HISA 189 -28067-47210 46170 1007039 A ATOM 1583 CD ARGA 199 ■11265-39077 35538 1006313 A ATOM 1499 NDl HISA 189 28860 -46271 47979 1007039 A ATOM 1584 NE ARGA 199 11034-38589 36897 1006313 A ATOM 1500 CEl HIS A 189 -29445 -45688 46948 1007039 A ATOM 1585 CZ ARGA 199 -11955-38011 37665 1006313 A ATOM 1501 NE2HISA189 -28980 -4624045839 1007039 A ATOM 1586 NHl ARG A 199 -13192-37845 37217 1006313 A ATOM 1502 C HISA 189 -25369-47866 50190 1006284 A ATOM 1587 NH2ARGA199 -11635-37596 38889 1006313 A ATOM 1503 O HISA 189 -25869-47608 51290 1006284 A ATOM 1588 C ARG A 199 -1155941913 33086 1005101 A ATOM 1504 N GLU A 190 -24347-48694 50037 1004173 A ATOM 1589 O ARG A 199 -10749-42824 32977 1005101 A ATOM 1505 CA GLUA 190 23714-49325 51173 1004173 A ATOM 1590 N ALA A 200 -11791 -41042 32111 1005584 A ATOM 1506 CB GLUA 190 -22754-50397 50674 10010304 A ATOM 1591 CA ALA A 200 11057-41 122 30853 1005584 A ATOM 1507 CG GLUA 190 -22451 -51497 51664 1007746 A ATOM 1592 CB ALA A 200 -11449 -3998429943 1005179 A ATOM 1508 CD GLUA 190 -21579-52585 51062 1007746 A ATOM 1593 C ALA A 200 -9551-41088 31117 1005584 A ATOM 1509 OEl GLUA 190 -20409 -52295 50726 1007746 A ATOM 1594 O ALA A 200 -9068-40301 31931 1005584 A ATOM 1510 OE2GLUA190 -22063-53729 50912 1007746 A ATOM 1595 N ASP A 201 -8823 -41963 30425 1006105 A ATOM 1511 C GLU A 190 -22952-48231 51929 1004173 A ATOM 1596 CA ASP A 201 7373 -42077 30563 1006105 A ATOM 1512 O GLU A 190 -23220-48001 53096 1004173 A ATOM 1597 CB ASP A 201 -687043213 29669 10012823 A ATOM 1513 N THR A 191 -22039-47548 51235 1004261 A ATOM 1598 CG ASP A 201 -7410-43117 28249 10012823 A ATOM 1514 CA THRA 191 ■21205 -46503 51805 1004261 A ATOM 1599 ODl ASP A 201 -8638-43285 28064 10012823 A ATOM 1515 CB THRA 191 -20031-46224 50876 1007501 A ATOM 1600 OD2ASPA201 -6611-42863 27319 10012823 A ATOM 1516 OGl THRA 191 -19229-47398 50781 1007501 A ATOM 1601 C ASP A 201 -6617-40787 30226 1006105 A ATOM 1517 CG2THRA191 -19190-45099 51394 1007501 A ATOM 1602 O ASP A 201 -5559 -40523 30788 1006105 A ATOM 1518 C THRA 191 21910 45184 52104 1004261 A ATOM 1603 N TRP A 202 -7160-3998029316 1005208 A ATOM 1519 O THR A 191 -21530 -44475 53041 1004261 A ATOM 1604 CA TRP A 202 -6497 -38749 28906 1005208 A ATOM 1520 N ARG A 192 -22921-44849 51304 1004754 A ATOM 1605 CB TRP A 202 -6887-38382 27477 1004450 A ATOM 1521 CA ARGA 192 -23679 -43609 51473 1004754 A ATOM 1606 CG TRP A 202 -8361 -38288 27216 1004450 A ATOM 1522 CB ARGA 192 24033 -43409 52945 1006807 A ATOM 1607 CD2TRPA202 -9190 -3713227373 1004450 A ATOM 1523 CG ARGA 192 -24983-44451 53456 1006807 A ATOM 1608 CE2TRPA202 -10501-3749726971 1004450 A ATOM 1524 CD ARGA 192 26266 -44442 52635 1006807 A ATOM 1609 CE3TRPA202 -8957-35822 27811 1004450 A ATOM 1525 NE ARGA 192 ■27158-45544 52992 1006807 A ATOM 1610 CDl TRP A 202 9178 39281 26742 1004450 A ATOM 1526 CZ ARGA 192 -27756 -45695 54176 1006807 A ATOM 1611 NEl TRP A 202 -10465-38812 26586 1004450 A ATOM 1527 NHl ARG A 192 -27574-44811 55147 1006807 A ATOM 1612 CZ2TRPA202 -11568 -36598 26998 1004450 A ATOM 1528 NH2ARGA192 -28536-46743 54403 1006807 A ATOM 1613 CZ3TRPA202 10019-34929 27836 1004450 A ATOM 1529 C ARG A 192 -22986 -4235750932 1004754 A ATOM 1614 CH2TRPA202 -11306-3532227433 1004450 A ATOM 1530 O ARG A 192 -23181 -41257 51443 1004754 A ATOM 1615 C TRP A 202 -6727 -37530 29784 1005208 A ATOM 1531 N HIS A 193 -22178 -4253049895 1003961 A ATOM 1616 O TRP A 202 -6070 -36499 29608 1005208 A ATOM 1532 CA HIS A 193 -21484-41415 49260 1003961 A ATOM 1617 N PHEA203 -7641-37643 30736 1005147 A ATOM 1533 CB HISA 193 -20209 -41039 50047 I 006626 A ATOM 1618 CA PHEA203 -7959-36518 31595 1005147 A ATOM 1534 CG HIS A 193 -19079-42012 49919 1006626 A ATOM 1619 CB PHEA203 -9477 -36444 31773 1004860 A ATOM 1535 CD2HISA193 -18823-42978 49009 1006626 A ATOM 1620 CG PHE A 203 -9948 -35207 32483 1004860 A ATOM 1536 NDl HIS A 193 -18005-42005 50776 1006626 A ATOM 1621 CDl PHE A 203 -9867 -33959 31867 1004860 A ATOM 1537 CEl HIS A 193 -17133-42923 50402 1006626 A ATOM 1622 CD2PHEA203 -10486-35287 33767 1004860 A ATOM 1538 NE2HISAI93 -17607 -43529 49330 1006626 A ATOM 1623 CEl PHE A 203 -10317-32808 32519 1004860 A ATOM 1539 C HIS A 193 -21180-41845 47815 1003961 A ATOM 1624 CE2PHEA203 -10939-34139 34428 1004860 A ATOM 1540 O HIS A 193 -2136943012 47464 1003961 A ATOM 1625 CZ PHE A 203 -10854 -32899 33802 1004860 A ATOM 1541 N GLY A 194 -20727 -40925 46968 1004608 A ATOM 1626 C PHE A 203 -7282-36557 32963 1005147 A ATOM 1542 CA GLYA 194 -20452-4129445590 1004608 A ATOM 1627 O PHE A 203 -7654 -37348 33822 1005147 A ATOM 1543 C GLYA 194 -19124 -4198945355 1004608 A ATOM 1628 N ASN A 204 -6277-35713 33164 1005493 A ATOM 1544 O GLY A 194 -18233-41933 46195 1004608 A ATOM 1629 CA ASN A 204 -5596 -35636 34459 1005493 A ATOM 1545 N ASNA 195 -18998-42657 44209 1004709 A ATOM 1630 CB ASN A 204 -4103 -35287 34286 1007969 A ATOM 1546 CA ASN A 195 -17765 -43355 43819 1004709 A ATOM 1631 CG ASN A 204 -3422 -34930 35609 1007969 A ATOM 1547 CB ASN A 195 -17880-44863 43985 1005756 A ATOM 1632 ODl ASN A 204 -3765-33931 36222 1007969 A ATOM 1548 CG ASN A 195 -17948-45287 45423 1005756 A ATOM 1633 ND2ASNA204 -2486 -35756 36070 1007969 A ATOM 1549 ODl ASNA 195 -17197-44791 46274 1005756 A ATOM 1634 C ASN A 204 -6332-34513 35196 1005493 A ATOM 1550 ND2ASNA 195 -18841-4622745714 1005756 A ATOM 1635 O ASN A 204 -6094 -33328 34950 1005493 A ATOM 1551 C ASNA 195 -1751143095 42355 1004709 A ATOM 1636 N ILE A 205 -7239-34884 36092 1005722 A ATOM 1552 O ASNA 195 -18449-43083 41547 1004709 A ATOM 1637 CA ILE A 205 -8030 -3389036805 1005722 A ATOM 1553 N VALA 196 -16254-42893 41992 1004004 A ATOM 1638 CB ILE A 205 -9017-34563 37781 1005857 A ATOM 1554 CA VALA 196 -15948 -42660 40589 I 004004 A ATOM 1639 CG2ILEA205 -8309 -34907 39075 1005857 A ATOM 1555 CB VAL A 196 -1458641996 40399 1004437 A ATOM 1640 CGl ILE A 205 -10188-33619 38065 1005857 A ATOM 1556 CGl VALA 196 14291 -41861 38923 1004437 A ATOM 1641 CDl ILE A 205 -11417-34318 38598 1005857 A ATOM 1557 CG2VALA196 -14582-4064041068 1004437 A ATOM 1642 C ILEA 205 -7214-3284637559 1005722 A ATOM 1558 C VALA 196 -15909-44017 39938 1004004 A ATOM 1643 O ILE A 205 -7728-31789 37920 1005722 A ATOM 1559 O VALA 196 -15105-44860 40328 1004004 A ATOM 1644 N SERA206 -5943-33139 37800 1005564 A ATOM 1560 N ASNA 197 -1678344238 38963 1005485 A ATOM 1645 CA SER A 206 -5077-32195 38505 1005564 A ATOM 1561 CA ASN A 197 -16833-45524 38276 1005485 A ATOM 1646 CB SER A 206 -3809-32888 38996 1006318 A ATOM 1562 CB ASN A 197 -18261 -45871 37860 1006356 A ATOM 1647 OG SER A 206 4114-33859 39979 1006318 A ATOM 1563 CG ASN A 197 -19252-45681 38972 1006356 A ATOM 1648 C SER A 206 -4688-31051 37592 1005564 A ATOM 1564 ODl ASNA 197 -19036-46131 40094 1006356 A ATOM 1649 O SER A 206 4282-30003 38051 1005564 A ATOM 1565 ND2ASNA197 -20362-45018 38664 1006356 A ATOM 1650 N ARG A 207 -4800-31261 36290 1005703 A ATOM 1566 C ASNA 197 -15974-45487 37027 1005485 A ATOM 1651 CA ARG A 207 -4455-30231 35336 1005703 A ATOM 1567 O ASNA 197 -15404-46489 36615 1005485 A ATOM 1652 CB ARG A 207 -3821 -30850 34088 1008518 A ATOM 1568 N PHEA 198 -15879-44318 36421 1004442 A ATOM 1653 CG ARG A 207 -2387-31307 34299 1008518 A 65251/C766

ATOM 1654 CD ARG A 207 -1573-31200 33017 1008518 A ATOM 1739 CA PHEA 218 -21431-35025 44064 1003675 A ATOM 1655 NE ARG A 207 -1 870-32267 32068 1008518 A ATOM 1740 CB PHE A 218 -20849 -36360 43620 1003871 A ATOM 1656 CZ ARG A 207 -1701 -32163 30752 1008518 A ATOM 1741 CG PHE A 218 -21888 -37385 43344 1003523 A ATOM 1657 NHl ARG A 207 1242-31033 30232 1008518 A ATOM 1742 CDl PHE A 218 -22546-37414 42129 1003523 A ATOM 1658 NH2 ARG A 207 -1982-33190 29956 1008518 A ATOM 1743 CD2 PHE A 218 -22260-38289 44321 1003523 A ATOM 1659 C ARG A 207 -5677 -29409 34949 1005703 A ATOM 1744 CEl PHE A 218 -23567 -38335 41 887 1003523 A ATOM 1660 O ARG A 207 5614 28601 34019 1005703 A ATOM 1745 CE2 PHE A 218 -23284 -39215 44089 1003523 A ATOM 1661 N SER A 208 -6788 -29608 35660 1004885 A ATOM 1746 CZ PHE A 218 -23935 -39236 42871 1003523 A ATOM 1662 CA SER A 208 -8019-28871 35373 1004885 A ATOM 1747 C PHE A 218 -22288 -35272 45302 1003675 A ATOM 1663 CB SER A 208 -9086 -29790 34780 1006431 A ATOM 1748 O PHE A 218 -23515 -35235 45227 1003675 A ATOM 1664 OG SER A 208 -10221-29034 34404 1006431 A ATOM 1749 N ASN A 219 -21650 -35538 46436 1004139 A ATOM 1665 C SER A 208 -8554 -28214 36634 1004885 A ATOM 1750 CA ASN A 219 -22404 -35790 47651 1004139 A ATOM 1666 O SER A 208 -9582-28600 37177 1004885 A ATOM 1751 CB ASN A 219 -21468 -35994 48842 I 004923 A ATOM 1667 N PRO A 209 -7848-27192 37108 1004221 A ATOM 1752 CG ASN A 219 -20484-37122 48618 1004086 A ATOM 1668 CD PRO A 209 -6703 -26624 36381 1004415 A ATOM 1753 ODl ASN A 219 -20801 -38104 47964 1004086 A ATOM 1669 CA PRO A 209 -8143-26394 38299 1004221 A ATOM 1754 ND2 ASN A 219 -19288-36990 49169 1004086 A ATOM 1670 CB PRO A 209 -7216-25191 38146 1004415 A ATOM 1755 C ASN A 219 23337 34623 47910 1004139 A ATOM 1671 CG PRO A 209 -6062 -25762 37433 I 004415 A ATOM 1756 O ASN A 219 -24499-34831 48248 1004139 A ATOM 1672 C PRO A 209 -9589 -25940 38434 1004221 A ATOM 1757 N PHE A 220 -22843 -33395 47737 1004147 A ATOM 1673 O PRO A 209 -10065-25710 39538 1004221 A ATOM 1758 CA PHE A 220 -23675 -32216 47966 1004147 A ATOM 1674 N HIS A 210 -10285-25805 37312 1004571 A ATOM 1759 CB PHE A 220 -22901 -30938 47692 1004650 A ATOM 1675 CA HIS A210 -11650 -25320 37340 1004571 A ATOM 1760 CG PHE A 220 -23775 -29723 47587 1003948 A ATOM 1676 CB HIS A 210 -11824 24274 36245 1005761 A ATOM 1761 CDl PHE A 220 -24153 -29024 48724 1003948 A ATOM 1677 CG HIS A 210 -10967-23065 36454 1005761 A ATOM 1762 CD2 PHE A 220 -24251 -29292 46338 1003948 A ATOM 1678 CD2 HIS A 210 -9846 -22645 35822 1005761 A ATOM 1763 CEl PHE A 220 -24987 -27914 48640 1003948 A ATOM 1679 NDl HIS A 210 11 193 22163 37473 1005761 A ATOM 1764 CE2 PHE A 220 -25091 -28182 46240 1003948 A ATOM 1680 CEl HIS A 210 -10248-21240 37458 1005761 A ATOM 1765 CZ PHE A 220 -25460 -27488 47402 1003948 A ATOM 1681 NE2 HIS A 210 -9417-21510 36467 1005761 A ATOM 1766 C PHE A 220 -24916-32238 47082 1004147 A ATOM 1682 C HIS A 210 ■12727-26377 37277 1004571 A ATOM 1767 O PHE A 220 -26042-32141 47572 1004147 A ATOM 1683 O HIS A 210 -13904 -26055 37149 1004571 A ATOM 1768 N TRP A 221 -24710 -32368 45776 1003921 A ATOM 1684 N THR A 211 -12325-27641 37357 1004941 A ATOM 1769 CA TRP A 221 -25820-32383 44838 1003921 A ATOM 1685 CA THR A 211 -13294 -28724 37385 1004941 A ATOM 1770 CB TRP A 221 -25294 -32322 43404 1004013 A ATOM 1686 CB THR A 211 -12693 -30046 36903 1005423 A ATOM 1771 CG TRP A 221 -24756 -30973 43040 1003328 A ATOM 1687 OGl THR A 211 -12303-29921 35530 1005423 A ATOM 1772 CD2 TRP A 221 -25491 -29740 43013 1003328 A ATOM 1688 CG2 THR A 211 -13714-31 161 37025 1005423 A ATOM 1773 CE2 TRP A 221 -24576 -28716 42666 1003328 A ATOM 1689 C THR A 21 1 -13575 -28804 38879 1004941 A ATOM 1774 CE3 TRP A 221 -26836-29399 43251 1003328 A ATOM 1690 O THR A 21 1 -12647 -28886 39670 1004941 A ATOM 1775 CDl TRP A 221 -23465 -30655 42714 1003328 A ATOM 1691 N PRO A 212 -14851 -28745 39286 1004327 A ATOM 1776 NEl TRP A 221 -23349 -29305 42490 1003328 A ATOM 1692 CD PRO A 212 -16031-28722 38400 1003706 A ATOM 1777 CZ2 TRP A 221 -24966 -27368 42548 1003328 A ATOM 1693 CA PRO A 212 -15254-28807 40700 1004327 A ATOM 1778 CZ3 TRP A 221 -27221 -28061 43134 1003328 A ATOM 1694 CB PRO A 212 -16764-28994 40619 1003706 A ATOM 1779 CH2 TRP A 221 -26286 -27064 42785 1003328 A ATOM 1695 CG PRO A 212 -17128-28299 39338 1003706 A ATOM 1780 C TRP A 221 -26753 -33578 45005 1003921 A ATOM 1696 C PRO A 212 -14587-29915 41528 1004327 A ATOM 1781 O TRP A 221 -27978-33435 45019 1003921 A ATOM 1697 O PRO A 212 -14401 -31044 41049 1004327 A ATOM 1782 N TYR A 222 -26187-34767 45129 1004419 A ATOM 1698 N GLY A 213 -14241 29586 42771 1005543 A ATOM 1783 CA TYR A 222 -27023 -35942 45295 1004419 A ATOM 1699 CA GLY A 213 -13605 -30547 43658 1005543 A ATOM 1784 CB TYR A 222 -26180-37166 45628 1004677 A ATOM 1700 C GLY A 213 -14610 -31434 44369 1005543 A ATOM 1785 CG TYR A 222 -27037-38331 46033 1004534 A ATOM 1701 O GLY A 213 -15813 31283 44171 1005543 A ATOM 1786 CDl TYR A 222 -27699 -39095 45073 1004534 A ATOM 1702 N ASN A 214 -14122-32354 45201 1008560 A ATOM 1787 CEl TYR A 222 -28559-40117 45440 1004534 A ATOM 1703 CA ASN A 214 -14989 -33288 45929 1008560 A ATOM 1788 CD2 TYRA 222 -27256-38621 47379 1004534 A ATOM 1704 CB ASN A 214 -15961 -32561 46853 1008484 A ATOM 1789 CE2 TYR A 222 -28114-39631 47765 1004534 A ATOM 1705 CG ASN A 214 -15336-31389 47546 1007901 A ATOM 1790 CZ TYR A 222 -28767 -40379 46786 1004534 A ATOM 1706 ODl ASN A 214 -14117-31252 47581 1007901 A ATOM 1791 OH TYR A 222 -29648 -41378 47133 1004534 A ATOM 1707 ND2 ASN A 214 -16169-30531 48117 1007901 A ATOM 1792 C TYR A 222 -28017-35713 46426 1004419 A ATOM 1708 C ASN A 214 -15806 -34070 44925 1008560 A ATOM 1793 O TYR A 222 29226 35877 46268 1004419 A ATOM 1709 O ASN A 214 -17025 -34164 45050 1008560 A ATOM 1794 N SER A 223 -27487 -35334 47576 1004277 A ATOM 1710 N ASP A 215 -15130 -34625 43927 1006807 A ATOM 1795 CA SER A 223 -28311 -35102 48740 1004277 A ATOM 1711 CA ASP A 215 -15802-35381 42893 1006807 A ATOM 1796 CB SER A 223 -27419 -34764 49927 1006440 A ATOM 1712 CB ASP A 215 -16218-36751 43419 10019265 A ATOM 1797 OG SER A 223 -28212 -34374 51027 1006302 A ATOM 1713 CG ASP A 215 -15046-37538 43947 10011403 A ATOM 1798 C SER A 223 -29361 -34004 48541 1004277 A ATOM 1714 ODl ASP A 215 -14072-37730 43188 10011403 A ATOM 1799 O SER A 223 -30539-34210 48818 1004277 A ATOM 1715 OD2 ASP A 215 -15094-37958 45122 10011403 A ATOM 1800 N LEU A 224 -28933 -32845 48055 1003716 A ATOM 1716 C ASP A 215 -17011 -34597 42436 1006807 A ATOM 1801 CA LEU A 224 -29846-31737 47863 1003716 A ATOM 1717 O ASP A 215 -18148 -35042 42604 1006807 A ATOM 1802 CB LEU A 224 -29069 -30468 47520 1005565 A ATOM 1718 N TYR A 216 -16746-33408 41 892 1003267 A ATOM 1803 CG LEU A 224 -29947 -29236 47326 1003289 A ATOM 1719 CA TYR A 216 -17792-32541 41355 1003267 A ATOM 1804 CDl LEU A 224 -30864 -29021 48523 1003289 A ATOM 1720 CB TYR A 216 18421-33183 40111 1006075 A ATOM 1805 CD2 LEU A 224 -29049 -28047 47101 1003289 A ATOM 1721 CG TYR A 216 -17417-33603 39060 1003950 A ATOM 1806 C LEU A 224 -30869 -32036 46786 1003716 A ATOM 1722 CDI TYR A 216 -16535-34657 39291 1003950 A ATOM 1807 O LEU A 224 -31986-31549 46843 1003716 A ATOM 1723 CEl TYR A 216 -15599 -35034 38344 1003950 A ATOM 1808 N MET A 225 -30493 -32829 45792 1005159 A ATOM 1724 CD2 TYR A 216 -17335-32930 37837 1003950 A ATOM 1809 CA MET A 225 -31429-33170 44723 1005159 A ATOM 1725 CE2 TYR A 216 -16405 -33294 36878 1003950 A ATOM 1810 CB MET A 225 -30685 -33700 43515 1007987 A ATOM 1726 CZ TYR A 216 -15537-34349 37136 1003950 A ATOM 1811 CG MET A 225 -29869 -32644 42846 1004859 A ATOM 1727 OH TYR A 216 -14614-34722 36180 1003950 A ATOM 1812 SD MET A 225 29148-33211 41334 1004859 A ATOM 1728 C TYR A 216 -18902 -32207 42346 1003267 A ATOM 1813 CE MET A 225 -30641-33518 40391 1004859 A ATOM 1729 O TYR A 216 -20063 -32056 41946 1003267 A ATOM 1814 C MET A 225 -32409 -34212 45226 1005159 A ATOM 1730 N ASN A 217 -18544 -32072 43624 1003854 A ATOM 1815 O META 225 -33573 -34222 44857 1005159 A ATOM 1731 CA ASN A 217 -19521-31774 44663 1003854 A ATOM 1816 N LYS A 226 -31927-35103 46075 1004281 A ATOM 1732 CB ASN A 217 -20056-30355 44499 1004928 A ATOM 1817 CA LYS A 226 -32783-36119 46649 1004281 A ATOM 1733 CG ASN A 217 -18978-29305 44630 1004401 A ATOM 1818 CB LYS A 226 -31967-37009 47582 10010478 A ATOM 1734 ODl ASN A 217 -18807 -28476 43747 1004401 A ATOM 1819 CG LYS A 226 -32763-38116 48212 1005624 A ATOM 1735 ND2 ASN A 217 -18250-29326 45738 1004401 A ATOM 1820 CD LYS A 226 -31948 -38831 49248 1005624 A ATOM 1736 C ASN A 217 20683 -32758 44562 1003854 A ATOM 1821 CE LYS A 226 -32807 -39768 50077 1005624 A ATOM 1737 O ASN A 217 -21833 -32379 44795 1003854 A ATOM 1822 NZ LYS A 226 -31988-40472 51 121 1005624 A ATOM 1738 N PHE A 218 -20388-34013 44215 1003675 A ATOM 1823 C LYS A 226 -33862 -35362 47442 1004281 A 65251/C766

ATOM 1824 O LYS A 226 -35040 -35662 47337 1004281 A ATOM 1909 CA SER A 237 -49 659 -33 496 40409 1 00116 35 A ATOM 1825 N GLU A 227 -33447 -34371 48230 1005788 A ATOM 1910 CB SER A 237 -50 584 -32 274 40 311 1 00 8654 A ATOM 1826 CA GLU A 227 -34384 -33582 49026 I 005788 A ATOM 1911 OG SER A 237 -49 928 -31 084 40 722 1 00 86 54 A ATOM 1827 CB GLU A 227 -33644-32494 49811 10015102 A ATOM 1912 C SER A 237 -48 314 -33 160 39 765 1 00116 35 A ATOM 1828 CG GLU A 227 -34537 -31709 50757 10012682 A ATOM 1913 O SER A 237 -48 258 -32 711 38 620 1 00116 35 A ATOM 1829 CD GLU A 227 -33888-30434 51263 10012682 A ATOM 1914 N THR A 238 -47 233 -33 374 40510 1 00113 89 A ATOM 1830 OEl GLU A 227 -32750 30500 51777 10012682 A ATOM 1915 CA THR A 238 -45 888 -33 101 40 013 1 00113 89 A ATOM 1831 OE2 GLU A 227 -34522-29363 51 153 10012682 A ATOM 1916 CB THR A 238 -45 174 -32 036 40 873 1 00115 30 A ATOM 1832 C GLU A 227 -35407 -32926 48102 1005788 A ATOM 1917 OGl THR A 238 -46 068 -30948 41 138 1 001 15 30 A ATOM 1833 O GLU A 227 -36601 -32982 48350 1005788 A ATOM 1918 CG2 THR A 238 -43 950 -31 504 40 142 1 00115 30 A ATOM 1834 N THR A 228 -34926 -32314 47026 1004668 A ATOM 1919 C THR A 238 -45 050 -34377 40051 1 00113 89 A ATOM 1835 CA THR A 228 -35785 -31632 46077 1004668 A ATOM 1920 O THR A 238 -44090 -34519 39 296 1 00113 89 A ATOM 1836 CB THR A 228 -34969 -30947 44992 1005519 A ATOM 1921 N LYS A 239 -45426 -35293 40943 1 0012067 A ATOM 1837 OGl THR A 228 -34065 -30023 45603 10041 18 A ATOM 1922 CA LYS A 239 -44 738 -36 571 41 121 1 00120 67 A ATOM 1838 CG2 THR A 228 -35895-30209 44017 10041 18 A ATOM 1923 CB LYS A 239 -45 754 -37 667 41 472 1 0012762 A ATOM 1839 C THR A 228 -36767 -32567 45404 1004668 A ATOM 1924 CG LYS A 239 -45 138 -39 029 41 755 1 00127 62 A ATOM 1840 O THR A 228 -37919-32214 45182 1004668 A ATOM 1925 CD LYS A 239 -46 157 -39 982 42 349 1 00127 62 A ATOM 1841 N LEU A 229 -36313 -33760 45065 1006053 A ATOM 1926 CE LYS A 239 -46 661 -39 478 43 693 1 00127 62 A ATOM 1842 CA LEU A 229 -37193 -34708 44421 1006053 A ATOM 1927 NZ LYS A 239 47 665 -40 402 44286 1 00127 62 A ATOM 1843 CB LEU A 229 -36395 -35918 43959 1007094 A ATOM 1928 C LYS A 239 -43 937 -36 970 39 885 1 00120 67 A ATOM 1844 CG LEU A 229 -37186-36998 43215 1004282 A ATOM 1929 O LYS A 239 -44482 -37079 38 789 1 00120 67 A ATOM 1845 CDl LEU A 229 -38147 -36371 42196 1004282 A ATOM 1930 N THR A 240 -42 639 -37 185 40069 1 00 63 35 A ATOM 1846 CD2 LEU A 229 -36205 37946 42526 1004282 A ATOM 1931 CA THR A 240 41 765 -37 546 38 964 1 0063 35 A ATOM 1847 C LEU A 229 -38319-35131 45371 1006053 A ATOM 1932 CB THR A 240 -40 882 -36 361 38 546 1 00 76 02 A ATOM 1848 O LEU A 229 -39470-35251 44956 1006053 A ATOM 1933 OGl THR A 240 -41 703 -35 227 38252 1 00 76 02 A ATOM 1849 N GLU A 230 -37991 35344 46644 1006522 A ATOM 1934 CG2 THR A 240 -40069 -36 717 37 321 1 00 76 02 A ATOM 1850 CA GLU A 230 -38990 -35739 47632 1006522 A ATOM 1935 C THR A 240 40 847 -38 689 39 324 1 00 63 35 A ATOM 1851 CB GLU A 230 -38325-35991 48990 10014289 A ATOM 1936 O THR A 240 -40 551 -38 916 40 499 1 00 63 35 A ATOM 1852 CG GLU A 230 -37461 -37246 49018 10010735 A ATOM 1937 N THR A 241 -40386 -39 389 38 294 1 00 63 92 A ATOM 1853 CD GLU A 230 -36841 -37512 50381 10010735 A ATOM 1938 CA THR A 241 -39 483 -40 520 38 443 1 0063 92 A ATOM 1854 OEl GLU A 230 -37594-37524 51377 10010735 A ATOM 1939 CB THR A 241 -39 33441 269 37 136 1 00106 81 A ATOM 1855 OE2 GLU A 230 -35608-37717 50456 10010735 A ATOM 1940 OGl THR A 241 -40 626 41 523 36 591 1 00 66 51 A ATOM 1856 C GLU A 230 -40073 -34669 47764 1006522 A ATOM 1941 CG2 THR A 241 -38 601 -42 575 37 356 1 00 66 51 A ATOM 1857 O GLU A 230 -41259-34988 47751 1006522 A ATOM 1942 C THR A 241 -38085 40071 38 834 1 0063 92 A ATOM 1858 N GLU A 231 -39665 -33405 47879 1006515 A ATOM 1943 O THR A 241 -37436 40 686 39 692 1 00 63 92 A ATOM 1859 CA GLU A 231 -40610 -32299 48013 1006515 A ATOM 1944 N SER A 242 37622 -38 999 38 192 1 00 69 96 A ATOM 1860 CB GLU A 231 -39865 -30972 48182 10014265 A ATOM 1945 CA SER A 242 -36285 -38 478 38447 1 00 69 96 A ATOM 1861 CG GLU A 231 -38883 -30947 49342 10011889 A ATOM 1946 CB SER A 242 -35 291 -39 163 37 520 I 00 7643 A ATOM 1862 CD GLU A 231 -39561 -31013 50697 10011889 A ATOM 1947 OG SER A 242 -35 597 -38 849 36 174 1 0048 95 A ATOM 1863 OEl GLU A 231 -40346-31957 50929 10011889 A ATOM 1948 C SERA 242 -36 140 -36 970 38 280 1 00 69 95 A ATOM 1864 OE2 GLU A 231 -39299-30119 51533 10011889 A ATOM 1949 O SER A 242 -37 038 -36 290 37 786 1 00 69 96 A ATOM 1865 C GLU A 231 -41494-32233 46771 1006515 A ATOM 1950 N LEU A 243 -34971 -36 476 38 683 1 00 42 66 A ATOM 1866 O GLU A 231 -42710 -32078 46862 1006515 A ATOM 1951 CA LEU A 243 -34 624 -35 064 38 627 1 0042 66 A ATOM 1867 N ILE A 232 -40871 -32355 45607 1008141 A ATOM 1952 CB LEU A 243 -34 701 -34464 40027 1 00 67 62 A ATOM 1868 CA ILE A 232 -41595 -32308 44345 1008141 A ATOM 1953 CG LEU A 243 -34 657 -32 945 40 107 1 0043 75 A ATOM 1869 CB ILE A 232 -40637 -32471 43149 1008486 A ATOM 1954 CDl LEU A 243 -35 799 -32 368 39 287 1 00 43 75 A ATOM 1870 CG2 ILE A 232 -41408 -32790 41903 1005491 A ATOM 1955 CD2 LEU A 243 -34788 -32 504 41 560 1 0043 75 A ATOM 1871 CGl ILE A 232 39843-31 183 42940 1005491 A ATOM 1956 C LEU A 243 -33 203 -34 955 38 095 1 0042 66 A ATOM 1872 CDl ILE A 232 -38849 -31257 41805 1005491 A ATOM 1957 O LEU A 243 -32 338 -35 754 38 445 1 00 42 66 A ATOM 1873 C ILE A 232 42665 -33384 44262 1008141 A ATOM 1958 N SER A 244 -32 964 -33 980 37 233 1 003822 A ATOM 1874 O ILE A 232 -43717 -33 168 43666 1008141 A ATOM 1959 CA SER A 244 -31 634 -33 790 36655 1 00 38 22 A ATOM 1875 N ASN A 233 -42406 -34538 44863 1007471 A ATOM 1960 CB SER A 244 -31 603 -34252 35 198 1 00 28 73 A ATOM 1876 CA ASN A 233 -43373 -35623 44823 1007471 A ATOM 1961 OG SER A 244 -31 770 -35 645 35 082 1 0030 88 A ATOM 1877 CB ASN A 233 -42674 -36968 44999 1006862 A ATOM 1962 C SER A 244 -31 135 -32 346 36 692 1 003822 A ATOM 1878 CG ASN A 233 -41834 -37342 43802 1005754 A ATOM 1963 O SER A 244 -31 900 -31 394 36477 1 003822 A ATOM 1879 ODl ASN A 233 -42164 -36994 42675 1005754 A ATOM 1964 N LEU A 245 -29 844 -32 189 36 967 1 00 37 10 A ATOM 1880 ND2 ASN A 233 -40749 -38070 44037 1005754 A ATOM 1965 CA LEU A 245 -29 223 -30 873 36 989 1 0037 10 A ATOM 1881 C ASN A 233 -44529-35527 45816 1007471 A ATOM 1966 CB LEU A 245 28 427 -30 665 38 266 1 00 53 99 A ATOM 1882 O ASN A 233 -45489-36291 45704 1007471 A ATOM 1967 CG LEU A 245 -27 669 -29 333 38276 1 00 37 98 A ATOM 1883 N LYS A 234 -44454-34612 46781 1008066 A ATOM 1968 CDl LEU A 245 -28 661 -28 200 38 121 1 003798 A ATOM 1884 CA LYS A 234 -45541 -34472 47748 1008066 A ATOM 1969 CD2 LEU A 245 26 860 -29 170 39 569 1 00 3798 A ATOM 1885 CB LYS A 234 -45131 -33538 48885 10011156 A ATOM 1970 C LEU A 245 -28 288 -30 824 35 784 1 00 37 10 A ATOM 1886 CG LYS A 234 -44152-34202 49837 10011156 A ATOM 1971 O LEU A 245 -27 235 -31 445 35 778 1 0037 10 A ATOM 1887 CD LYS A 234 -43767-33313 51001 10011156 A ATOM 1972 N ILE A 246 -28 688 -30098 34750 1 00 36 39 A ATOM 1888 CE LYS A 234 -42S20-34052 51937 10011156 A ATOM 1973 CA ILE A 246 -27 893 -29 998 33 531 1 0036 39 A ATOM 1889 NZ LYS A 234 -42295-33176 53021 10011156 A ATOM 1974 CB ILE A 246 -28 793 -30 085 32 278 1 0052 87 A ATOM 1890 C LYS A 234 46830 33998 47071 1008066 A ATOM 1975 CG2 ILE A 246 -27947 -30080 31 021 1 00 35 91 A ATOM 1891 O LYS A 234 -47905 -34540 47337 1008066 A ATOM 1976 CGl ILE A 246 -29 631 -31 359 32 322 1 00 35 91 A ATOM 1892 N ASN A 235 -46738 -32987 46207 I 0012783 A ATOM 1977 CDl ILE A 246 -28 821 -32 601 32 478 1 00 35 91 A ATOM 1893 CA ASN A 235 -47920-32539 45473 10012783 A ATOM 1978 C ILE A 246 ■ ■27 158 -28 671 33 503 1 00 36 39 A ATOM 1894 CB ASN A 235 -47697-31 167 44817 10015099 A ATOM 1979 O ILE A 246 • -27769 -27609 33 501 1 00 36 39 A ATOM 1895 CG ASN A 235 -48867-30748 43925 10015099 A ATOM 1980 N THR A 247 -25 837 -28 721 33 489 1 0041 29 A ATOM 1896 ODl ASN A 235 -49378-31564 43161 10015099 A ATOM 1981 CA THR A 247 -25 059 -27489 33 461 1 00 41 29 A ATOM 1897 ND2 ASN A 235 -49284-29485 44005 10015099 A ATOM 1982 CB THR A 247 -24 660 27064 34 890 1 0043 90 A ATOM 1898 C ASN A 235 -48031 -33618 44398 10012783 A ATOM 1983 OGl THR A 247 -24 136 -25 733 34 868 I 0041 14 A ATOM 1899 O ASN A 235 -47209 -33676 43486 10012783 A ATOM 1984 CG2 THRA 247 -23 623 -28 013 35 464 1 0041 14 A ATOM 1900 N ASP A 236 -49038 -34477 44518 10013349 A ATOM 1985 C THR A 247 23 820 -27 715 32 608 1 0041 29 A ATOM 1901 CA ASP A 236 -49226 -35586 43584 10013349 A ATOM 1986 O THR A 247 -23 321 -28 834 32 535 1 0041 29 A ATOM 1902 CB ASP A 236 -50411-36441 44039 10014139 A ATOM 1987 N GLY A 248 -23 340 -26 666 31 953 1 002923 A ATOM 1903 CG ASP A 236 -50318 -37876 43556 10014139 A ATOM 1988 CA GLY A 248 -22 181 -26 796 31 088 1 0029 23 A ATOM 1904 ODl ASP A 236 -50489 -38113 42342 10014139 A ATOM 1989 C GLY A 248 -22 021 -25 594 30 173 1 002923 A ATOM 1905 OD2 ASP A 236 -50068 -38769 44394 10014139 A ATOM 1990 O GLY A 248 -22 716 -24 585 30 327 1 0029 23 A ATOM 1906 C ASP A 236 -49396-35216 42108 10013349 A ATOM 1991 N CYS A 249 -21 105 -25 678 29222 1 004032 A ATOM 1907 O ASP A 236 49424 -36100 41252 10013349 A ATOM 1992 CA CYS A 249 -20 886 -24560 28 312 1 0040 32 A ATOM 1908 N SER A 237 -49501 -33925 41802 10011635 A ATOM 1993 CB CYS A 249 -19 808 -23 618 28 852 1 00 28 15 A 65251/C766

ATOM 1994 SG CYS A 249 -18 108 -24 253 28 735 1 004692 A ATOM 2079 CA GLY A 260 -27564 2447934139 1004369 A ATOM 1995 C CYS A 249 -20485 -25 038 26 923 1 00 40 32 A ATOM 2080 C GLY A 260 -29047 -2451034389 1004369 A ATOM 1996 O CYS A 249 -20 347 -26242 26684 1 0040 32 A ATOM 2081 O GLY A 260 -29634 -2348834736 1004369 A ATOM 1997 N TYR A 250 -20 290 -24093 26 008 1 0028 82 A ATOM 2082 N TYR A 261 29666 2566234187 1003805 A ATOM 1998 CA TYR A 250 -19 943 -24 435 24 640 1 00 28 82 A ATOM 2083 CA TYR A 261 -31091-2578734413 1003805 A ATOM 1999 CB TYR A 250 21 208 -24 804 23 874 1 0040 60 A ATOM 2084 CB TYRA 261 -31837 -2559833106 1005266 A ATOM 2000 CG TYR A 250 -22 175 -23 653 23 765 1 00 3095 A ATOM 2085 CG TYRA 261 -31492 -2661332044 1003645 A ATOM 2001 CDl TYR A 250 -22 109 -22 756 22 697 1 00 30 95 A ATOM 2086 CDl TYR A 261 -32166 -2783831966 1003645 A ATOM 2002 CEl TYR A 250 -22 980 -21 660 22 620 1 00 30 95 A ATOM 2087 CEl TYR A 261 -31911 -2873230932 1003645 A ATOM 2003 CD2 TYR A 250 23 133 -23 431 24755 1 00 30 95 A ATOM 2088 CD2 TYR A 261 -30540 -2632031064 1003645 A ATOM 2004 CE2 TYR A 250 -24002 -22 348 24 692 1 00 30 95 A ATOM 2089 CE2 TYR A 261 -30272 -2721230024 1003645 A ATOM 2005 CZ TYR A 250 -23 923 -21 464 23 627 1 003095 A ATOM 2090 CZ TYR A 261 -30962 -2840929962 1003645 A ATOM 2006 OH TYR A 250 -24764 -20374 23 596 1 00 3095 A ATOM 2091 OH TYR A 261 -30718-2926728917 1003645 A ATOM 2007 C TYR A 250 -19 254 -23 305 23 899 1 00 28 82 A ATOM 2092 C TYR A 261 -31444 -2712535038 1003805 A ATOM 2008 O TYR A 250 -19 429 -22 132 24218 1 00 28 82 A ATOM 2093 O TYR A 261 -30628 -2805035065 1003805 A ATOM 2009 N GLU A 251 -18 472 -23 702 22 901 1 00 55 77 A ATOM 2094 N VAL A 262 -32665-2721335551 1004688 A ATOM 2010 CA GLU A 251 17 759 -22 806 22 016 1 00 55 77 A ATOM 2095 CA VALA 262 -33144-2841636196 1004688 A ATOM 2011 CB GLU A 251 -16274 -22 779 22 347 1 00122 74 A ATOM 2096 CB VAL A 262 -33636 -2809937630 1003520 A ATOM 2012 CG GLU A 251 -15 828 -21 442 22 885 1 00 76 36 A ATOM 2097 CGl VAL A 262 -34379 -2929538220 1002669 A ATOM 2013 CD GLU A 251 -14319 -21 340 23 060 1 00 76 36 A ATOM 2098 CG2 VAL A 262 32458 2773538509 1002669 A ATOM 2014 OEl GLU A 251 -13 580 -21 568 22 074 1 00 76 36 A ATOM 2099 C VAL A 262 -34297 -2895835388 1004688 A ATOM 2015 OE2 GLU A 251 -13 869 -21 021 24 185 1 00 76 36 A ATOM 2100 O VAL A 262 -35240 -2823035119 1004688 A ATOM 2016 C GLU A 251 -17 992 -23 443 20652 1 00 55 77 A ATOM 2101 N GLU A 263 -34213-3021934974 1003993 A ATOM 2017 O GLU A 251 -17 161 -24 191 20 154 1 00 55 77 A ATOM 2102 CA GLU A 263 -35314 -3083434247 1003993 A ATOM 2018 N THR A 252 -19 162 -23 174 20 081 1 00 42 72 A ATOM 2103 CB GLU A 263 -34921 -3121532823 1008013 A ATOM 2019 CA THR A 252 -19 570 -23 692 18 776 1 00 42 72 A ATOM 2104 CG GLU A 263 -33723-32091 32721 1006673 A ATOM 2020 CB THR A 252 -21 080 -23 968 18 766 1 0048 59 A ATOM 2105 CD GLU A 263 -33407 -3244731285 1006673 A ATOM 2021 OGl THR A 252 -21 408 -24 809 19 878 1 0048 59 A ATOM 2106 OEl GLU A 263 -33528 -3155230409 1006673 A ATOM 2022 CG2 THR A 252 21 500 24 655 17479 1 0048 59 A ATOM 2107 OE2 GLU A 263 -33024 -3361731034 1006673 A ATOM 2023 C THR A 252 -19 260 -22 632 17 723 1 00 42 72 A ATOM 2108 C GLU A 263 -35830 -3205535007 1003993 A ATOM 2024 O THR A 252 -20 060 -21 725 17 503 1 00 42 72 A ATOM 2109 O GLU A 263 -35146-32621 35859 1003993 A ATOM 2025 N GLY A 253 -18 107 -22 740 17 071 1 0046 62 A ATOM 2110 N THR A 264 -37058 -3243534683 1006103 A ATOM 2026 CA GLY A 253 -17746 -21 734 16 091 1 0046 62 A ATOM 2111 CA THR A 264 -37753-3354335311 1006103 A ATOM 2027 C GLY A 253 -17601 -20395 16797 1 004662 A ATOM 2112 CB THR A 264 -39066 -3300835928 1008507 A ATOM 2028 O GLY A 253 -16 918 -20298 17 821 1 00 46 62 A ATOM 2113 OGl THR A 264 -38876 -3279737329 1006400 A ATOM 2029 N LEU A 254 -18 251 -19 367 16 265 1 0041 88 A ATOM 2114 CG2 THR A 264 -40222-33933 35691 1006400 A ATOM 2030 CA LEU A 254 -18 193 -18 045 16 866 1 0041 88 A ATOM 2115 C THR A 264 -38031-34598 34260 1006103 A ATOM 2031 CB LEU A 254 -18 667 -16 978 15 880 1 0041 55 A ATOM 2116 O THR A 264 -37873 -3434033075 1006103 A ATOM 2032 CG LEU A 254 -17 799 -16 639 14 678 1 0041 55 A ATOM 2117 N ALA A 265 -38418 3579434680 1006002 A ATOM 2033 CDl LEU A 254 -18 413 -15 434 13 983 1 00 41 55 A ATOM 2118 CA ALA A 265 -38725 -3684233711 1006002 A ATOM 2034 CD2 LEU A 254 -16368 -16 346 15 120 1 0041 55 A ATOM 2119 CB ALA A 265 -39104-3813234435 1008986 A ATOM 2035 C LEU A 254 -19 062 17954 18 110 1 0041 88 A ATOM 2120 C ALA A 265 -39891 36353 32832 1006002 A ATOM 2036 O LEU A 254 -18 769 -17 171 19 013 1 00 41 88 A ATOM 2121 O ALA A 265 -40075 -3682231708 1006002 A ATOM 2037 N LEU A 255 -20 136 -18 739 18 148 1 00 39 50 A ATOM 2122 N ASN A 266 -40660 -35395 33355 1006957 A ATOM 203 S CA LEU A 255 -21 045 -18 718 19284 1 0039 50 A ATOM 2123 CA ASN A 266 -41807 -3482532655 1006957 A ATOM 2039 CB LEU A 255 -22 335 -19 458 18945 1 00 3493 A ATOM 2124 CB ASN A 266 -42836-3429833652 10013829 A ATOM 2040 CG LEU A 255 -23 024 -19 026 17 654 1 003493 A ATOM 2125 CG ASN A 266 -43261-3534434646 1008014 A ATOM 2041 CDl LEU A 255 -24331 19 802 17 505 1 00 34 93 A ATOM 2126 ODl ASN A 266 -43640 -3645934272 1008014 A ATOM 2042 CD2 LEU A 255 -23 290 -17 535 17 671 1 00 34 93 A ATOM 2127 ND2 ASN A 266 -43202 -3499735929 1008014 A ATOM 2043 C LEU A 255 -20429 -19330 20 538 1 00 39 50 A ATOM 2128 C ASN A 266 -41410-3369631714 1006957 A ATOM 2044 O LEU A 255 19 582 20224 20 459 1 00 39 50 A ATOM 2129 O ASN A 266 -42206 -3327930871 1006957 A ATOM 2045 N PHE A 256 -20 851 -18 832 21 698 1 00 36 06 A ATOM 2130 N GLY A 267 40185-3319431860 1006766 A ATOM 2046 CA PHE A 256 -20 362 -19 353 22 962 1 0036 06 A ATOM 2131 CA GLY A 267 -39719 -3211730999 1006766 A ATOM 2047 CB PHE A 256 18 945 -18 836 23 228 1 0041 07 A ATOM 2132 C GLY A 267 -39017-30991 31732 1006766 A ATOM 2048 CG PHE A 256 -18 862 -17 350 23439 1 003808 A ATOM 2133 O GLY A 267 -38987-30981 329571006766 A ATOM 2049 CDl PHE A 256 18 856 -16 817 24 716 1 00 38 08 A ATOM 2134 N PRO A 268 -38451-3001431006 1005639 A ATOM 2050 CD2 PHE A 256 -18 779 -16 475 22 356 1 00 38 08 A ATOM 2135 CD PRO A 268 -38666 -2979229570 1004581 A ATOM 2051 CEl PHE A 256 -18 766 -15 442 24 913 1 0038 08 A ATOM 2136 CA PRO A 268 -37741 -2887331595 1005639 A ATOM 2052 CE2 PHE A 256 -18 689 -15 091 22 554 1 00 38 08 A ATOM 2137 CB PRO A 268 -37524 -2794530407 1006170 A ATOM 2053 CZ PHE A 256 -18 682 -14584 23 830 1 00 38 08 A ATOM 2138 CG PRO A 268 -38653 -2829229499 1004581 A ATOM 2054 C PHE A 256 -21 305 -18 961 24 087 1 00 3606 A ATOM 2139 C PRO A 268 -38533 2821532701 1005639 A ATOM 2055 O PHE A 256 -21 889 -17 883 24 059 1 00 3606 A ATOM 2140 O PRO A 268 -39732 -2799332566 1005639 A ATOM 2056 N GLY A 257 -21 467 -19 848 25 064 1 00 49 71 A ATOM 2141 N LEU A 269 -37848 -2789633792 1005892 A ATOM 2057 CA GLY A 257 -22 342 -19 557 26 184 1 0049 71 A ATOM 2142 CA LEU A 269 -38481 -27293 34955 1005892 A ATOM 2058 C GLY A 257 -22 303 -20650 27 234 1 00 49 71 A ATOM 2143 CB LEU A 269 -38136-2813036186 1008877 A ATOM 2059 O GLY A 257 -21 567 -21 629 27 087 1 0049 71 A ATOM 2144 CG LEU A 269 -38972-2790937429 1005411 A ATOM 2060 N SER A 25S -23 086 -20490 28 298 1 00 3540 A ATOM 2145 CDl LEU A 269 -40430 -2809037074 1005411 A ATOM 2061 CA SER A 258 -23 130 -21 488 29 360 1 0035 40 A ATOM 2146 CD2 LEU A 269 -38554 -2888438502 1005411 A ATOM 2062 CB SER A 258 -22 272 -21 050 30 542 1 00 41 52 A ATOM 2147 C LEU A 269 -38068 -2582935160 1005892 A ATOM 2063 OG SER A 258 22 838 19 925 31 180 1 00 51 64 A ATOM 2148 O LEU A 269 -38860 -2491734916 1005892 A ATOM 2054 C SER A 258 -24 571 -21 670 29 811 1 003540 A ATOM 2149 N ALA A 270 -36834 -25601 35601 1005743 A ATOM 2065 O SER A 258 -25 416 -20 818 29 545 1 00 35 40 A ATOM 2150 CA ALA A 270 -36346 -2424335841 1005743 A ATOM 2066 N TYR A 259 -24 856 -22 762 30 504 1 00 41 55 A ATOM 2151 CB ALA A 270 -36438-2389837318 1003648 A ATOM 2067 CA TYRA 259 -26 217 -23 002 30944 1 0041 55 A ATOM 2152 C ALA A 270 -34924-2402035371 1005743 A ATOM 2068 CB TYR A 259 -26 975 -23 785 29 864 1 0046 65 A ATOM 2153 O ALA A 270 -34073-24901 35457 1005743 A ATOM 2069 CG TYR A 259 -26239 -25 033 29431 1 004240 A ATOM 2154 N ARG A 271 -34672-2280334913 1004873 A ATOM 2070 CDl TYR A 259 -26313 -26211 30 177 1 00 42 40 A ATOM 2155 CA ARG A 271 -33372 -2238034388 1004873 A ATOM 2071 CEl TYRA 259 -25 560 -27 314 29 839 1 00 42 40 A ATOM 2156 CB ARG A 271 -33604 -2177433003 1005545 A ATOM 2072 CD2 TYR A 259 -25 388 -25 008 28 329 1 00 4240 A ATOM 2157 CG ARG A 271 -32454 -2102432402 1004857 A ATOM 2073 CE2 TYRA 259 -24628 -26 118 27 990 1 00 4240 A ATOM 2158 CD ARG A 271 32868 -2039031074 1004857 A ATOM 2074 CZ TYR A 259 -24 722 -27 258 28 751 1 0042 40 A ATOM 2159 NE ARG A 271 -33093 -2137330022 1004857 A ATOM 2075 OH TYR A 259 -23 952 -28 336 28 421 1 0042 40 A ATOM 2160 CZ ARG A 271 -34287-2171629554 1004857 A ATOM 2076 C TYR A 259 -26235 23 775 32 241 1 0041 55 A ATOM 2161 NHl ARG A 271 -35378 -21149 30046 1004857 ATOM 2077 O TYR A 259 -25 236 -24371 32 637 1 0041 55 A A ATOM 2078 N GLY A 260 -27 389 -23 765 32 895 1 00 43 69 A 65251/C766

ATOM 2162 NH2 ARG A 271 -34 384 22 628 28 593 1 0048 57 A ATOM 2247 CG LYS A 281 -41252-19130 34716 1008217 A ATOM 2163 C ARG A 271 -32 740 -21 361 35 335 1 0048 73 A ATOM 2248 CD LYS A 281 -42275 -18765 33650 1008217 A ATOM 2164 O ARG A 271 -33 411 -20 456 35 817 1 0048 73 A ATOM 2249 CE LYS A 281 -43689-19201 34023 1008217 A ATOM 2165 N TYR A 272 31 452 -21 508 35 608 1 0049 18 A ATOM 2250 NZ LYS A 281 -44700 -1877932993 1008217 A ATOM 2166 CA TYR A 272 -30773 -20 602 36 528 1 0049 18 A ATOM 2251 C LYS A 281 -39132 -21245 33388 1005303 A ATOM 2167 CB TYRA 272 -29 679 -21 338 37 291 1 004045 A ATOM 2252 O LYS A 281 -38735 -20292 32719 1005303 A ATOM 2168 CG TYR A 272 -28 959 -20 476 38 301 1 00 37 92 A ATOM 2253 N MET A 282 -39162-22488 32920 1004621 A ATOM 2169 CDl TYR A 272 -29 511 -20231 39 561 1 00 37 92 A ATOM 2254 CA META 282 -38775 -22794 31546 1004621 A ATOM 2170 CEl TYR A 272 -28 876 -19 374 40476 1 00 37 92 A ATOM 2255 CB MET A 282 -37836 -24000 31483 1006091 A ATOM 2171 CD2 TYR A 272 -27 748 -19 850 37 983 1 00 37 92 A ATOM 2256 CG META 282 -36443 -23744 32022 1006091 A ATOM 2172 CE2 TYR A 272 -27 113 -18998 38 893 1 0037 92 A ATOM 2257 SD MET A 282 -35284-2502031505 1006091 A ATOM 2173 CZ TYR A 272 -27 687 -18 769 40 129 1 00 3792 A ATOM 2258 CE MET A 282 -35491-26194 32787 1006091 A ATOM 2174 OH TYRA 272 -27082 -17 929 41 022 1 00 3792 A ATOM 2259 C MET A 282 -40030-23115 30762 1004621 A ATOM 2175 C TYR A 272 -30 148 -19433 35 800 1 00 49 18 A ATOM 2260 O MET A 282 -39991 -23233 29542 1004621 A ATOM 2176 O TYR A 272 -29 317 -19 626 34918 1 00 49 18 A ATOM 2261 N THR A 283 -41140 -23248 31482 1006503 A ATOM 2177 N HIS A 273 ■ -30 536 -18 217 36 174 1 00 70 65 A ATOM 2262 CA THR A 283 -42430 -23572 30895 1006503 A ATOM 2178 CA HIS A 273 -29 992 -17023 35 533 1 00 70 65 A ATOM 2263 CB THR A 283 -42804-25037 31195 1005748 A ATOM 2179 CB HIS A 273 -31 104 -16018 35 222 1 00133 16 A ATOM 2264 OGl THR A 283 -41868 -2589730547 1005748 A ATOM 2180 CG HIS A 273 -31 958 -16419 34060 1 00113 89 A ATOM 2265 CG2 THR A 283 -44189 -25369 30685 1005748 A ATOM 2181 CD2 HIS A 273 33 284 -16 678 33 972 1 00113 89 A ATOM 2266 C THR A 283 -43480-22670 31511 1006503 A ATOM 2182 NDl HIS A 273 -31 442 -16 630 32 800 1 00113 89 A ATOM 2267 O THR A 283 -43257 -22130 32589 1006503 A ATOM 2183 CEl HIS A 273 -32 413 -17 002 31 985 1 00113 89 A ATOM 2268 N HIS A 284 -44612-2250030821 1007166 A ATOM 2184 NE2 HIS A 273 -33 541 -17 040 32 672 1 00113 89 A ATOM 2269 CA HIS A 284 -45726-21688 31317 1007166 A ATOM 2185 C HIS A 273 ■ -28 901 -16 361 36 347 1 00 70 65 A ATOM 2270 CB HIS A 284 -46894 -21739 30323 10015986 A ATOM 2186 O HIS A 273 -29 101 -15 945 37486 1 007065 A ATOM 2271 CG HIS A 284 -47372 -2312930020 10015986 A ATOM 2187 N THR A 274 -27730 -16289 35 733 1 00 59 27 A ATOM 2272 CD2 HIS A 284 -48555-23742 30270 10015986 A ATOM 2188 CA THR A 274 -26 551 -15 691 36 333 1 00 5927 A ATOM 2273 NDl HIS A 284 -46582 24071 29394 10015986 A ATOM 2189 CB THR A 274 -25 387 -15 752 35 334 1 00 62 69 A ATOM 2274 CEl HIS A 284 -47256 -25202 29273 10015986 A ATOM 2190 OGl THR A 274 -24 586 -16 900 35 626 1 00 55 22 A ATOM 2275 NE2 HIS A 284 -48456 -25029 29797 10015986 A ATOM 2191 CG2 THR A 274 -24 550 -14493 35 384 1 00 55 22 A ATOM 2276 C HIS A 284 46180-22260 32671 1007166 A ATOM 2192 C THR A 274 -26 789 -14251 36 763 1 00 59 27 A ATOM 2277 O HIS A 284 -46545-21518 33591 1007166 A ATOM 2193 O THR A 274 -26265 -13 804 37 782 1 00 59 27 A ATOM 2278 N LYS A 285 -46125 -2358932769 1009253 A ATOM 2194 N GLY A 275 -27 577 -13 523 35 980 1 00 54 93 A ATOM 2279 CA LYS A 285 -46520-24351 33954 1009253 A ATOM 2195 CA GLY A 275 -27 864 -12 139 36 305 1 00 54 93 A ATOM 2280 CB LYS A 285 -46138 -25826 33765 10014103 A ATOM 2196 C GLY A 275 -28 712 -11 969 37 553 1 00 54 93 A ATOM 2281 CG LYS A 285 -47266-26810 34026 10014103 A ATOM 2197 O GLY A 275 -28263 -11 400 38 548 1 00 54 93 A ATOM 2282 CD LYS A 285 -48396-26643 33013 10014103 A ATOM 2198 N ASP A 276 -29 942 -12 469 37 502 1 00 58 31 A ATOM 2283 CE LYS A 285 -49528 -27630 33270 10014103 A ATOM 2199 CA ASP A 276 -30 869 -12 374 38 626 1 00 58 31 A ATOM 2284 NZ LYS A 285 -50630 -27488 32279 10014103 A ATOM 2200 CB ASP A 276 -32256 -12 819 38 170 1 0014635 A ATOM 2285 C LYS A 285 -45924 -2384735264 1009253 A ATOM 2201 CG ASP A 276 -32 677 -12 155 36 886 1 00125 35 A ATOM 2286 O LYS A 285 -46548 -23968 36314 1009253 A ATOM 2202 ODl ASP A 276 -32 914 -10 929 36 905 1 00125 35 A ATOM 2287 N GLY A 286 -44721 -23283 35204 1007104 A ATOM 2203 OD2 ASP A 276 32 759 12 858 35 854 1 00125 35 A ATOM 2288 CA GLY A 286 -44067 -22799 36410 1007104 A ATOM 2204 C ASP A 276 -30 458 -13 205 39 845 1 0058 31 A ATOM 2289 C GLY A 286 -43319 -23937 37086 1007104 A ATOM 2205 O ASP A 276 -30951 -12 966 40 948 1 00 58 31 A ATOM 2290 O GLY A 286 -43283 -25056 36568 1007104 A ATOM 2206 N LYS A 277 -29 571 -14 181 39 649 1 00 54 13 A ATOM 2291 N PHE A 287 -42711 -23668 38235 1006953 A ATOM 2207 CA LYS A 277 -29 129 -15 052 40738 1 0054 13 A ATOM 2292 CA PHE A 287 -41980 -24709 38956 1006953 A ATOM 2208 CB LYS A 277 -28 400 -14235 41 807 1 0090 93 A ATOM 2293 CB PHE A 287 -40492 -24678 38590 1005933 A ATOM 2209 CG LYS A 277 -27 083 -13 659 41 335 1 00 76 14 A ATOM 2294 CG PHE A 287 -39764 -23465 39093 1005933 A ATOM 2210 CD LYS A 277 -26 584 -12 592 42288 1 00 76 14 A ATOM 2295 CDl PHE A 287 -39244 2343440383 1005933 A ATOM 2211 CE LYS A 277 -25 220 -12 043 41 871 1 00 76 14 A ATOM 2296 CD2 PHE A 287 -39599 -22347 38279 1005933 A ATOM 2212 NZ LYS A 277 -24 085 -12 982 42 165 1 00 76 14 A ATOM 2297 CEl PHE A 287 -38566 -2230240856 1005933 A ATOM 2213 C LYS A 277 -30323 -15 799 41 352 1 00 54 13 A ATOM 2298 CE2 PHE A 287 38923-21211 38742 1005933 A ATOM 2214 O LYS A 277 -30514 -15 818 42 564 1 0054 13 A ATOM 2299 CZ PHE A 287 -38406 -2118840032 1005933 A ATOM 2215 N ARG A 278 -31 122 -16415 40 492 1 00 57 61 A ATOM 2300 C PHE A 287 -42151-2454440460 1006953 A ATOM 2216 CA ARG A 278 -32 291 -17 169 40 920 1 00 57 61 A ATOM 2301 O PHE A 287 -42169 -23422 40980 1006953 A ATOM 2217 CB ARG A 278 -33 402 -16 210 41 327 1 00127 22 A ATOM 2302 N PRO A 288 -42275 -2566841179 1005913 A ATOM 2218 CG ARG A 278 -33 984 -15 471 40 149 1 00111 85 A ATOM 2303 CD PRO A 288 -42166 -2704440666 1004283 A ATOM 2219 CD ARG A 278 -34 884 -14 342 40 581 1 00111 85 A ATOM 2304 CA PRO A 288 -42447 -25662 42633 1005913 A ATOM 2220 NE ARG A 278 -35 537 -13 710 39 436 1 00111 85 A ATOM 2305 CB PRO A 288 -42690 -27132 42953 1004283 A ATOM 2221 CZ ARG A 278 -36 152 -12 532 39481 1 00111 85 A ATOM 2306 CG PRO A 288 -41871 -2783941928 1004283 A ATOM 2222 NHl ARG A 278 -36 197 11 850 40 619 1 00111 85 A ATOM 2307 C PRO A 288 -41235 -2509843367 1005913 A ATOM 2223 NH2 ARG A 278 -36723 -12 037 38 389 1 00111 85 A ATOM 2308 O PRO A 288 -40116-2557443188 1005913 A ATOM 2224 C ARG A 278 -32 766 -18 032 39 745 1 00 57 61 A ATOM 2309 N LYS A 289 -41456 -2407644188 1007743 A ATOM 2225 O ARG A 278 -32 301 -17 861 38 617 1 00 57 61 A ATOM 2310 CA LYS A 289 -40363 -23473 44934 1007743 A ATOM 2226 N PHE A 279 -33 679 -18 963 40 006 1 00 52 63 A ATOM 2311 CB LYS A 289 -40702 -2202045286 1009916 A ATOM 2227 CA PHE A 279 -34200 -19 808 38 943 1 00 52 63 A ATOM 2312 CG LYS A 289 -40539-21074 44094 1009916 A ATOM 2228 CB PHE A 279 -34638 -21 170 39486 1 0061 73 A ATOM 2313 CD LYS A 289 -40885 -1964044440 1009916 A ATOM 2229 CG PHE A 279 -33 513 -22 135 39 695 1 0045 50 A ATOM 2314 CE LYS A 289 -42382 19477 44659 1009916 A ATOM 2230 CDl PHE A 279 -32 863 -22 211 40 918 1 0045 50 A ATOM 2315 NZ LYS A 289 -42762-18071 44974 1009916 A ATOM 2231 CD2 PHE A 279 -33 091 -22 960 38 661 1 0045 50 A ATOM 2316 C LYS A 289 JtO 033 -24290 46180 1007743 A ATOM 2232 CEl PHE A 279 -31 802 -23 099 41 109 1 0045 50 A ATOM 2317 O LYS A 289 -40406 -23941 47299 1007743 A ATOM 2233 CE2 PHE A 279 -32 036 -23 845 38 844 1 0045 50 A ATOM 2318 N VAL A 290 -39312-25385 45955 1006658 A ATOM 2234 CZ PHE A 279 -31 389 -23 915 40070 1 0045 50 A ATOM 2319 CA VAL A 290 -38907 -26301 47007 1006658 A ATOM 2235 C PHE A 279 -35 398 -19 142 38277 1 005263 A ATOM 2320 CB VAL A 290 -39789 -2756247005 1005578 A ATOM 2236 O PHE A 279 -36 089 -18 331 38 895 1 0052 63 A ATOM 2321 CGl VAL A 290 -41245 -27162 47014 1005578 A ATOM 2237 N THR A 280 -35 639 -19 488 37 015 1 00 48 01 A ATOM 2322 CG2 VAL A 290 -39483 -2841045782 1005578 A ATOM 2238 CA THR A 280 -36 770 -18 950 36278 1 0048 01 A ATOM 2323 C VAL A 290 -37466 -2673446782 1006658 A ATOM 2239 CB THR A 280 -36 334 -17 912 35 265 1 0092 88 A ATOM 2324 O VAL A 290 -36896 -26485 45723 1006658 A ATOM 2240 OGl THR A 280 -35 499 -16950 35 910 1 00 73 40 A ATOM 2325 N GLY A 291 -36892 -27395 47781 1005199 A ATOM 2241 CG2 THR A 280 37549 17 213 34 677 1 00 73 40 A ATOM 2326 CA GLY A 291 -35524 -2786047679 1005199 A ATOM 2242 C THR A 280 .37464 -20067 35 521 1 004801 A ATOM 2327 C GLYA 291 -34508 -2684247192 1005199 A ATOM 2243 O THR A 280 -36 804 -20 926 34 942 1 00 4801 A ATOM 2328 O GLY A 291 -34467 -2569447648 1005199 A ATOM 2244 N LYS A 281 -38 794 -20 047 35 528 1 0053 03 A ATOM 2329 N META 292 -33682 -2728046249 1005990 A ATOM 2245 CA LYS A 281 -39 594 -21 050 34 833 1 00 53 03 A ATOM 2330 CA MET A 292 32636 2645045672 1005990 A ATOM 2246 CB LYS A 281 -41 064 -20 629 34854 1 0010623 A ATOM 2331 CB MET A 292 -31713 -2730744820 1006079 A 65251/C766

ATOM 2332 CG MET A 292 -32410 -27 800 43 569 1 00 60 79 A ATOM 2417 CG ASP A 302 -23332 -24477 50196 1008665 A ATOM 2333 SD MET A 292 -31 290 -28 366 42 287 1 00 60 79 A ATOM 2418 ODl ASP A 302 -22186 -23979 50197 1008665 A ATOM 2334 CE MET A 292 -31 702 30 095 42 244 1 00 6079 A ATOM 2419 OD2 ASP A 302 23885 -24920 51225 1008665 A ATOM 2335 C MET A 292 -33 200 -25 357 44 785 1 00 59 90 A ATOM 2420 C ASP A 302 -24495 -23406 46695 1004662 A ATOM 2336 O MET A 292 -32 446 -24 576 44212 1 0059 90 A ATOM 2421 O ASP A 302 -23641 -23572 45820 1004662 A ATOM 2337 N LEU A 293 -34 519 -25 300 44 664 1 00 73 36 A ATOM 2422 N VAL A 303 -25803 -23384 46440 1003738 A ATOM 2338 CA LEU A 293 -35 141 -24 309 43 802 1 00 7336 A ATOM 2423 CA VALA 303 -26298 -23543 45084 1003738 A ATOM 2339 CB LEU A 293 -36 302 -24 956 43 052 1 0046 30 A ATOM 2424 CB VAL A 303 -27820 -23507 45035 1003627 A ATOM 2340 CG LEU A 293 -35913 -26 073 42 075 1 00 4630 A ATOM 2425 CGl VAL A 303 -28291 -23514 43600 1002558 A ATOM 2341 CDl LEU A 293 -37 165 -26 708 41 492 1 00 46 30 A ATOM 2426 CG2 VAL A 303 -28381 -24700 45766 1002558 A ATOM 2342 CD2 LEU A 293 -35 052 -25 496 40 966 1 00 46 30 A ATOM 2427 C VAL A 303 -25744 -22398 44260 1003738 A ATOM 2343 C LEU A 293 -35 603 22 996 44436 1 00 73 36 A ATOM 2428 O VAL A 303 -25133 -22625 43219 1003738 A ATOM 2344 O LEU A 293 -36063 -22 107 43 724 1 00 73 36 A ATOM 2429 N LYS A 304 -25938 -21169 44738 1005276 A ATOM 2345 N THR A 294 -35 488 -22 854 45 754 1 00 71 51 A ATOM 2430 CA LYS A 304 -25443-19984 44038 1005276 A ATOM 2346 CA THR A 294 35 903 21 603 46 390 1 00 71 51 A ATOM 2431 CB LYS A 304 -25599 -18736 44904 1008584 A ATOM 2347 CB THR A 294 -37088 -21 780 47 325 1 00 88 17 A ATOM 2432 CG LYS A 304 -26951-18068 44857 1006776 A ATOM 2348 OGl THR A 294 -38 015 -22 698 46747 1 00 88 17 A ATOM 2433 CD LYS A 304 -26948 -16863 45782 1006776 A ATOM 2349 CG2 THR A 294 -37782 -20436 47 539 1 00 88 17 A ATOM 2434 CE LYS A 304 -28257-16110 45713 1006776 A ATOM 2350 C THR A 294 -34 820 -20 974 47 228 1 00 71 51 A ATOM 2435 NZ LYS A 304 28322-15027 46722 1006776 A ATOM 2351 O THR A 294 -33 978 -21 663 47 793 1 00 71 51 A ATOM 2436 C LYS A 304 -23974 -20135 43692 1005276 A ATOM 2352 N VAL A 295 -34 858 -19 652 47 322 1 00 72 74 A ATOM 2437 O LYS A 304 23546 -19869 42572 1005276 A ATOM 2353 CA VAL A 295 -33 885 -18 940 48 122 1 00 72 74 A ATOM 2438 N ALA A 305 -23201 -20561 44671 1005443 A ATOM 2354 CB VAL A 295 -34015 -17 432 47 907 1 00 9046 A ATOM 2439 CA ALA A 305 -21772-20731 44492 1005443 A ATOM 2355 CGl VAL A 295 -32924 -16690 48687 1 009046 A ATOM 2440 CB ALA A 305 -21 126 -20937 45852 1001797 A ATOM 2356 CG2 VAL A 295 -33 930 -17 126 46421 1 00 90 46 A ATOM 2441 C ALA A 305 -21365 -21857 43539 1005443 A ATOM 2357 C VAL A 295 -34 156 -19284 49 587 1 00 72 74 A ATOM 2442 O ALA A 305 -20578 -21634 42617 1005443 A ATOM 2358 O VAL A 295 -33 281 -19 140 50448 1 00 72 74 A ATOM 2443 N TYR A 306 -21891 -23060 43761 1004371 A ATOM 2359 N LYS A 296 -35 373 -19 756 49 851 1 00 63 22 A ATOM 2444 CA TYR A 306 -21545-24197 42919 1004371 A ATOM 2360 CA LYS A 296 -35 795 -20 135 51 197 1 0063 22 A ATOM 2445 CB TYR A 306 -21985 -25503 43583 1005374 A ATOM 2361 CB LYS A 296 -37241 -20 642 51 170 1 0010860 A ATOM 2446 CG TYR A 306 -21240 -25809 44853 1004843 A ATOM 2362 CG LYS A 296 -38 265 -19 629 50 675 1 00108 60 A ATOM 2447 CDl TYR A 306 -21844 -26530 45882 1004843 A ATOM 2363 CD LYS A 296 -38 532 -18 531 51 702 1 00108 60 A ATOM 2448 CEl TYR A 306 -21 166-26815 47046 1004843 A ATOM 2364 CE LYS A 296 -39 262 -19 076 52 922 1 00108 60 A ATOM 2449 CD2 TYR A 306 -19930-25384 45028 1004843 A ATOM 2365 NZ LYS A 296 39 522 18 027 53 947 1 00108 60 A ATOM 2450 CE2 TYR A 306 -19241 -25665 46188 1004843 A ATOM 2366 C LYS A 296 34900 -21 226 51 777 1 00 63 22 A ATOM 2451 CZ TYR A 306 -19863-26380 47191 1004843 A ATOM 2367 O LYS A 296 -34 668 -21 271 52 985 1 00 63 22 A ATOM 2452 OH TYR A 306 -19170-26673 48339 1004843 A ATOM 2368 N ASN A 297 -34 395 -22 099 50 908 1 00 51 25 A ATOM 2453 C TYR A 306 -22124-24121 41523 1004371 A ATOM 2369 CA ASN A 297 -33 547 -23 211 51 328 1 00 51 25 A ATOM 2454 O TYR A 306 21403 24283 40553 1004371 A ATOM 2370 CB ASN A 297 -33 203 -24 101 50 131 1 005665 A ATOM 2455 N LEU A 307 -23422 -23876 41420 1003614 A ATOM 2371 CG ASN A 297 -32 561 -25 413 50 548 1 00 56 65 A ATOM 2456 CA LEU A 307 -24076-23814 40123 1003614 A ATOM 2372 ODl ASN A 297 -31 487 -25430 51 152 1 0056 65 A ATOM 2457 CB LEU A 307 -25566 24127 40264 1005660 A ATOM 2373 ND2 ASN A 297 -33 224 -26 520 50 234 1 00 56 65 A ATOM 2458 CG LEU A 307 -26403 -23923 39003 1002473 A ATOM 2374 C ASN A 297 -32263 -22 800 52 034 1 00 51 25 A ATOM 2459 CDl LEU A 307 -25917-24828 37879 1002473 A ATOM 2375 O ASN A 297 -31 552 -21 892 51 615 1 00 51 25 A ATOM 2460 CD2 LEU A 307 27863-24210 39323 1002473 A ATOM 2376 N THR A 298 -31 964 -23 503 53 112 1 00 54 05 A ATOM 2461 C LEU A 307 -23889 -22455 39472 1003614 A ATOM 2377 CA THR A 298 -30 785 -23 223 53 903 1 00 5405 A ATOM 2462 O LEU A 307 -23467-22349 38314 1003614 A ATOM 2378 CB THR A 298 -30 769 -24 124 55 141 1 007209 A ATOM 2463 N GLY A 308 24201 -21406 40213 1005036 A ATOM 2379 OGl THR A 298 -29439 -24 194 55 658 1 00 72 09 A ATOM 2464 CA GLY A 308 .24044 -20077 39664 1005036 A ATOM 2380 CG2 THR A 298 -31 259 -25 512 54 788 1 00 7209 A ATOM 2465 C GLY A 308 -22611-19795 39252 1005036 A ATOM 2381 C THR A 298 -29473 -23 373 53 130 1 00 5405 A ATOM 2466 O GLY A 308 -22363-19297 38154 1005036 A ATOM 2382 O THR A 298 -28467 -22 760 53 478 1 00 54 05 A ATOM 2467 N GLY A 309 -21663-20115 40126 1003903 A ATOM 2383 N LEU A 299 -29483 -24 175 52 074 1 00 59 52 A ATOM 2468 CA GLY A 309 -20272 -19866 39812 1003903 A ATOM 2384 CA LEU A 299 -28270 -24393 51 284 1 00 59 52 A ATOM 2469 C GLY A 309 -19792-20559 38551 1003903 A ATOM 2385 CB LEU A 299 -28 146 -25 868 50903 1 00 52 64 A ATOM 2470 O GLY A 309 -19169-19935 37678 1003903 A ATOM 2386 CG LEU A 299 -27 918 -26 808 52083 1 0052 64 A ATOM 2471 N PHE A 310 -20087 -21 854 38459 1004220 A ATOM 2387 CDl LEU A 299 27938 28 238 51 604 1 00 52 64 A ATOM 2472 CA PHE A 310 -19679 -22664 37327 1004220 A ATOM 2388 CD2 LEU A 299 -26581 -26 475 52 741 1 00 52 64 A ATOM 2473 CB PHE A 310 -20207 24081 37500 1003900 A ATOM 2389 C LEU A 299 -28 185 -23 551 50 023 1 00 59 52 A ATOM 2474 CG FHE A 310 -19631 -25067 36526 1003483 A ATOM 2390 O LEU A 299 -27264 -23 719 49224 1 00 59 52 A ATOM 2475 CDl PHE A 310 -18262-25320 36496 1003483 A ATOM 2391 N TRP A 300 -29 141 -22 646 49 853 1 00 5496 A ATOM 2476 CD2 PHE A 310 -20459 -25762 35652 1003483 A ATOM 2392 CA TRP A 300 -29 172 -21 780 48 680 1 00 54 96 A ATOM 2477 CEl PHE A 310 -17731 -26254 35608 1003483 A ATOM 2393 CB TRP A 300 -30216 -20 679 48 867 1 00 57 00 A ATOM 2478 CE2 PHE A 310 -19937 -26694 34764 1003483 A ATOM 2394 CG TRP A 300 -30 335 -19 781 47 686 1 00 57 00 A ATOM 2479 CZ PHE A 310 18571 26944 34739 1003483 A ATOM 2395 CD2 TRPA 300 -30692 -20 169 46358 005700 A ATOM 2480 C PHE A 310 -20241 -22064 36050 1004220 A ATOM 2396 CE2 TRP A 300 -30 675 -18 998 45 562 00 57 00 A ATOM 2481 O PHE A 310 -19532 -21930 35036 1004220 A ATOM 2397 CE3 TRP A 300 -31 026 -21 393 45 760 00 57 00 A ATOM 2482 N GLU A 311 -21517-21 690 36115 1003500 A ATOM 2398 CDl TRP A 300 -30 120 -18 425 47 649 00 5700 A ATOM 2483 CA GLU A 311 -22199-21 131 34963 1003500 A ATOM 2399 NEl TRP A 300 -30 324 -17 950 46374 00 5700 A ATOM 2484 CB GLU A 311 -23704 -21094 35205 1009184 A ATOM 2400 CZ2 TRP A 300 -30 980 -19 017 44200 1 0057 00 A ATOM 2485 CG GLU A 31 1 -24508-21061 33923 1007607 A ATOM 2401 CZ3 TRP A 300 -31 330 -21 412 44407 1 005700 A ATOM 2486 CD GLU A 311 -25981 -20843 34159 1007607 A ATOM 2402 CH2 TRP A 300 -31 305 -20 230 43 641 1 00 5700 A ATOM 2487 OEl GLU A 311 -26532 -21406 35126 1007607 A ATOM 2403 C TRP A 300 -27 809 -21 145 48 384 1 0054 96 A ATOM 2488 OE2 GLU A 311 -26598 -20115 33364 1007607 A ATOM 2404 O TRP A 300 -27 384 -21 079 47223 1 00 5496 A ATOM 2489 C GLU A 311 -21699 -19734 34639 1003500 A ATOM 2405 N LYS A 301 -27 127 -20 684 49 430 1 0059 16 A ATOM 2490 O GLU A 311 -21628-19341 33482 1003500 A ATOM 2406 CA LYS A 301 -25 834 -20 049 49251 1 00 59 16 A ATOM 2491 N TYR A 312 -21333-18982 35661 1004268 A ATOM 2407 CB LYS A 301 -25 242 -19 617 50 603 00 74 35 A ATOM 2492 CA TYR A 312 -20863-17631 35438 1004268 A ATOM 2408 CG LYS A 301 -26 108 -18 609 51 370 00 74 35 A ATOM 2493 CB TYR A 312 -20792-16872 36751 1004853 A ATOM 2409 CD LYS A 301 -26 577 -17447 50475 00 74 35 A ATOM 2494 CG TYR A 312 -20383-15432 36559 1004323 A ATOM 2410 CE LYS A 301 -27 763 -16 691 51 082 00 74 35 A ATOM 2495 CDl TYR A 312 -21277 14500 36027 1004323 A ATOM 2411 NZ LYS A 301 -28476 -15 846 50 083 00 74 35 A ATOM 2496 CEl TYR A 312 -20904-13172 35818 1004323 A ATOM 2412 C LYS A 301 -24 879 -20971 48519 1 0059 16 A ATOM 2497 CD2 TYRA 312 -19092-15000 36883 1004323 A ATOM 2413 O LYS A 301 -24 084 -20 522 47 691 1 00 59 16 A ATOM 2498 CE2 TYR A 312 -18707 -13670 36675 1004323 A ATOM 2414 N ASP A 302 -24 960 -22 263 48 806 1 0046 62 A ATOM 2499 CZ TYR A 312 -19622-12763 36137 1004323 A ATOM 2415 CA ASP A 302 -24081 -23 210 48 143 1 0046 62 A ATOM 2500 OH TYR A 312 -19239-11461 35882 1004323 A ATOM 2416 CB ASP A 302 -24075 -24 548 48 879 1 00 86 65 A ATOM 2501 C TYR A 312 -19498 -17556 34769 1004268 A 65251/C766

ATOM 2502 O TYR A 312 -19246-16660 33972 1004268 A ATOM 2587 CB LYS A 324 -5010-28495 27063 1007776 A ATOM 2503 N MET A 313 -18600-18474 35097 1004373 A ATOM 2588 CG LYS A 324 -4790-27041 26807 1006719 A ATOM 2504 CA META 313 -17274-18410 34505 1004373 A ATOM 2589 CD LYS A 324 -3855 -2646427848 1006719 A ATOM 2505 CB MET A 313 16494 17272 35146 1005439 A ATOM 2590 CE LYS A 324 -3596 -24973 27594 1006719 A ATOM 2506 CG META 313 -15131 -17073 34555 1005424 A ATOM 2591 NZ LYS A 324 -2527-24399 28471 1006719 A ATOM 2507 SD META 313 -14199-15773 35398 1005424 A ATOM 2592 C LYS A 324 -5391 -30723 26103 1005333 A ATOM 2508 CE META 313 -15293-14432 35214 1005424 A ATOM 2593 O LYS A 324 -4632 -31285 25316 1005333 A ATOM 2509 C MET A 313 -16480-19703 34636 1004373 A ATOM 2594 N MET A 325 -5951 -31350 27131 1005440 A ATOM 2510 O META313 -15703 -2006033746 1004373 A ATOM 2595 CA META 325 -5678 -32753 27384 1005440 A ATOM 2511 N GLY A 314 -16677-20401 35749 1003456 A ATOM 2596 CB META 325 -6090 -33108 28804 1006842 A ATOM 2512 CA GLY A 314 -15957-21636 35979 1003456 A ATOM 2597 CG META 325 -5290 32354 29839 1005698 A ATOM 2513 C GLY A 314 -15888-22576 34792 1003456 A ATOM 2598 SD META 325 -5713-32721 31544 1005698 A ATOM 2514 O GLYA314 -14806-23009 34380 1003456 A ATOM 2599 CE MET A 325 -6876-31468 31891 1005698 A ATOM 2515 N CYSA315 -17050-22897 34243 1004113 A ATOM 2600 C MET A 325 6350 33687 26407 1005440 A ATOM 2516 CA CYS A 315 -17107-23802 33124 1004113 A ATOM 2601 O MET A 325 -6006 -34851 26339 1005440 A ATOM 2517 CB CYS A 315 -18556-24043 32731 1004754 A ATOM 2602 N ALA A 326 -7303 -3318725639 1005100 A ATOM 2518 SG CYS A 315 -18746-25461 31664 1005291 A ATOM 2603 CA ALA A 326 -7989 -34049 24697 1005100 A ATOM 2519 C CYS A 315 -16319-23304 31916 1004113 A ATOM 2604 CB ALA A 326 -9467 -33653 24611 1003202 A ATOM 2520 O CYS A 315 -15495-24037 31372 10041 13 A ATOM 2605 C ALA A 326 -7357 -3400623315 1005100 A ATOM 2521 N SER A 316 16562 22071 31487 1004204 A ATOM 2606 O ALA A 326 -7475 -34962 22552 1005100 A ATOM 2522 CA SERA 316 -15851-21540 30325 1004204 A ATOM 2607 N LYS A 327 -6677 -32903 23009 1008879 A ATOM 2523 CB SER A 316 -16252-20101 30063 1003742 A ATOM 2608 CA LYS A 327 -6062 -32688 21704 1008879 A ATOM 2524 OG SERA 316 -15795-19283 31 112 1004292 A ATOM 2609 CB LYS A 327 -4759 -3190721838 10016755 A ATOM 2525 C SERA 316 -14336-21604 30485 1004204 A ATOM 2610 CG LYS A 327 -4275 -31390 20499 1008584 A ATOM 2526 O SER A 316 -13609 -21676 29500 1004204 A ATOM 2611 CD LYS A 327 -3066 -30491 20632 1008584 A ATOM 2527 N LEU A 317 -13853 -21558 31720 1003903 A ATOM 2612 CE LYS A 327 -2663-29912 19276 1008584 A ATOM 2528 CA LEU A 317 -12424-21651 31959 1003903 A ATOM 2613 NZ LYS A 327 -1446-29046 19357 1008584 A ATOM 2529 CB LEUA 317 -12074-21060 33320 1005431 A ATOM 2614 C LYS A 327 -5813-3393020862 1008879 A ATOM 2530 CG LEU A 317 -12189-19537 33427 1004682 A ATOM 2615 O LYS A 327 -6450 -34127 19824 1008879 A ATOM 2531 CDl LEU A 317 -11960-19098 34864 1004682 A ATOM 2616 N GLY A 328 -4897-34781 21298 10O5780 A ATOM 2532 CD2LEUA317 -11162-18888 32516 1004682 A ATOM 2617 CA GLY A 328 -4626 -35963 20506 1005780 A ATOM 2533 C LEU A 317 -11990-23117 31909 1003903 A ATOM 2618 C GLY A 328 -5488-37196 20725 1005780 A ATOM 2534 O LEU A 317 -10985-23472 31287 1003903 A ATOM 2619 O GLY A 328 5633 38004 19815 1005780 A ATOM 2535 N ALA A 318 -12760-23974 32563 1003335 A ATOM 2620 N LYS A 329 -6087 -3734621902 1005427 A ATOM 2536 CA ALA A 318 -12450-25389 32595 1003335 A ATOM 2621 CA LYS A 329 6863 -3854622177 I 005427 A ATOM 2537 CB ALA A 318 -13452-26103 33483 1002327 A ATOM 2622 CB LYS A 329 -6694-38925 23648 10018760 A ATOM 2538 C ALA A 318 -12424-26028 31207 1003335 A ATOM 2623 CG LYS A 329 -5268-39307 24015 10018760 A ATOM 2539 O ALAA318 -11487-26758 30876 1003335 A ATOM 2624 CD LYS A 329 -5240-40070 25321 10018760 A ATOM 2540 N ILE A 319 -13441 -25746 30394 1004303 A ATOM 2625 CE LYS A 329 -3842 -40545 25673 1007736 A ATOM 2541 CA ILE A 319 -13520-26341 29066 1004303 A ATOM 2626 NZ LYS A 329 -3863 41325 26949 1007736 A ATOM 2542 CB ILE A 319 -14646-25709 28207 1005337 A ATOM 2627 C LYS A 329 -8338 -38669 21792 1005427 A ATOM 2543 CG2ILEA319 -14247 -2432427748 1002793 A ATOM 2628 O LYS A 329 -9020 -39565 22296 1005427 A ATOM 2544 CGl ILE A 319 -14893-26572 26971 1002793 A ATOM 2629 N ILE A 330 -8846 -37809 20912 1004216 A ATOM 2545 CDl ILE A 319 -16093-26150 26174 1002793 A ATOM 2630 CA ILE A 330 -10256-37946 20500 1004216 A ATOM 2546 C ILE A 319 12209 -2624928307 1004303 A ATOM 2631 CB ILE A 330 -11190-3697221277 1004941 A ATOM 2547 O ILE A 319 -11883-27132 27523 1004303 A ATOM 2632 CG2ILEA330 -10995-3714422783 1005033 A ATOM 2548 N LEU A 320 -11448-25190 28553 1004389 A ATOM 2633 CGl ILE A 330 -10910-3552720870 1005033 A ATOM 2549 CA LEU A 320 -10170-25011 27874 1004389 A ATOM 2634 CDl ILE A 330 -12004 -34572 21269 1005033 A ATOM 2550 CB LEU A 320 -9675 -23570 28044 1006607 A ATOM 2635 C ILE A 330 10418-37707 19006 1004216 A ATOM 2551 CG LEU A 320 -10558-2248627393 1004391 A ATOM 2636 O ILE A 330 -9482-37268 18352 1004216 A ATOM 2552 CDl LEU A 320 -9946-21132 27617 1004391 A ATOM 2637 N PRO A 331 -11608-37983 18449 1004262 A ATOM 2553 CD2LEUA320 -10717 -22740 25899 1004391 A ATOM 2638 CD PRO A 331 -12838-38443 19105 1002664 A ATOM 2554 C LEU A 320 -9108-26009 28343 1004389 A ATOM 2639 CA PRO A 331 -11848-37782 17015 1004262 A ATOM 2555 O LEU A 320 -8228 -2639927572 1004389 A ATOM 2640 CB PRO A 331 -13361-37881 16899 10017062 A ATOM 2556 N ASP A 321 -9185 -26429 29602 1004856 A ATOM 2641 CG PRO A 331 13688-38870 17910 1002664 A ATOM 2557 CA ASP A 321 -8235-27410 30109 1004856 A ATOM 2642 C PRO A 331 -11331 -36438 16539 1004262 A ATOM 2558 CB ASP A 321 -8297-27495 31635 1008928 A ATOM 2643 O PRO A 331 -11516-35427 17218 1004262 A ATOM 2559 CG ASP A 321 -7718-26266 32315 1006828 A ATOM 2644 N LYS A 332 -10671-36428 15381 1005424 A ATOM 2560 ODl ASP A 321 -6642-25801 31875 1006828 A ATOM 2645 CA LYS A 332 -10138-35194 14820 1005486 A ATOM 2561 OD2ASPA321 -8329 -25777 33300 1006828 A ATOM 2546 CB LYS A 332 -9168-35511 13688 10011949 A ATOM 2562 C ASP A 321 -8549-28781 29501 1004856 A ATOM 2647 CG LYS A 332 -9830-36263 12551 1009103 A ATOM 2563 O ASP A 321 -7639-29553 29178 1004856 A ATOM 2648 CD LYS A 332 -9038-36138 11267 1009103 A ATOM 2564 N TYR A 322 -9836 -29083 29346 1004767 A ATOM 2649 CE LYS A 332 -9818-36696 10087 1009103 A ATOM 2565 CA TYR A 322 -10231-3035428761 1004767 A ATOM 2650 NZ LYS A 332 -9109-36451 8799 1009103 A ATOM 2566 CB TYR A 322 -11755 -30494 28714 1005144 A ATOM 2651 C LYS A 332 -11286 -34330 14279 1005393 A ATOM 2567 CG TYRA 322 -12410-30816 30047 1004215 A ATOM 2652 O LYS A 332 -12370 -34826 13967 1005202 A ATOM 2568 CDl TYR A 322 -12496-29861 31057 1004215 A ATOM 2653 N ASP A 333 -11047-33031 14174 1006468 A ATOM 2569 CEl TYR A 322 -13133-30139 32264 1004215 A ATOM 2654 CA ASP A 333 -12061 -32132 13648 1006414 A ATOM 2570 CD2TYRA322 -12975-32066 30287 1004215 A ATOM 2655 CB ASP A 333 -11564-30686 13706 10014270 A ATOM 2571 CE2 TYRA 322 -13612-32350 31493 1004215 A ATOM 2656 CG ASP A 333 -11903-30007 15015 10011029 A ATOM 2572 CZ TYR A 322 -13688-31378 32470 1004215 A ATOM 2657 ODl ASP A 333 -11850-30670 16068 10011029 ATOM 2573 OH TYRA 322 -14343-3162733649 1004215 A A ATOM 2574 C TYR A 322 -9683 -30422 27346 1004767 A ATOM 2658 OD2ASPA333 -12214-28803 14996 10011029 ATOM 2575 O TYR A 322 -9065-31419 26944 1004767 A A ATOM 2576 N GLN A 323 -9914 -29348 26595 1006150 A ATOM 2659 C ASP A 333 -12367-32518 12208 1006799 A ATOM 2577 CA GLN A 323 -9468-29271 25223 1006150 A ATOM 2660 O ASP A 333 -11474-32894 11443 1006764 A ATOM 2578 CB GLN A 323 -9754 -27895 24658 I 007481 A ATOM 2661 N THR A 334 -13637-32435 11842 1003226 A ATOM 2579 CG GLN A 323 -9314-2776423238 1004920 A ATOM 2662 CA THR A 334 -14050-32761 10484 1003198 A ATOM 2580 CD GLN A 323 -9699 -26442 22642 1004920 A ATOM 2663 CB THR A 334 -14640-34167 10421 1006441 A ATOM 2581 OEl GLN A 323 -9427-25380 23223 1004920 A ATOM 2664 OG ITHR A 334 -13572-35113 10548 1005031 A ATOM 2582 NE2GLNA323 -10339-2648421470 1004920 A ATOM 2665 CG2THRA334 -15394-34391 9111 1005031 A ATOM 2583 C GLN A 323 -7987 -29589 25102 1006150 A ATOM 2666 C THR A 334 -15062-31755 9951 1003842 A ATOM 2584 O GLN A 323 -7595 -30368 24237 1006150 A ATOM 2667 O THR A 334 -16150-31591 10507 1003578 A ATOM 2585 N LYS A 324 -7167 -28996 25966 1005333 A ATOM 2668 N THR A 335 -14689-31085 8860 1005282 A ATOM 2586 CA LYS A 324 -5723 -29248 25945 1005333 A ATOM 2669 CA THR A 335 -15545-30077 8254 1005261 A 65251/C766

ATOM 2670 CB THR A 335 -14755-29200 7319 1006038 A ATOM 2755 C GLU A 346 -48750-27813 0619 10018727 A ATOM 2671 OGl THR A 335 -13542-28801 7970 1004974 A ATOM 2756 O GLU A 346 -49069-26841 -0072 10018727 A ATOM 2672 CG2THRA335 -15569-27978 6961 1004974 A ATOM 2757 N ASP A 347 -49243 28009 1840 10019207 A ATOM 2673 C THR A 335 -16708-30672 7496 1005347 A ATOM 2758 CA ASP A 347 -50204-27066 2418 10019207 A ATOM 2674 O THR A 335 -16548-31582 6708 1005482 A ATOM 2759 CB ASP A 347 -50710-27565 3782 10017430 A ATOM 2675 N PRO A 336 -17906-30146 7719 1004872 A ATOM 2760 CG ASP A 347 -49764-27234 4920 10017430 A ATOM 2676 CD FRO A 336 -18260-29063 8653 1004071 A ATOM 2761 ODl ASP A 347 -48608-27705 4900 10017430 A ATOM 2677 CA PRO A 336 -19098-30650 7048 1004830 A ATOM 2762 OD2ASPA347 -50184-26499 5840 10017430 A ATOM 2678 CB PRO A 336 20205 30215 7989 1004957 A ATOM 2763 C ASP A 347 49629-25659 2561 10019207 A ATOM 2679 CG PRO A 336 -19740-28841 8359 1004071 A ATOM 2764 O ASP A 347 -50332-24668 2351 10019207 A ATOM 2680 C PRO A 336 -19319-30100 5645 1004834 A ATOM 2765 N GLY A 348 -48349-25577 2915 10019033 A ATOM 2681 O PRO A 336 -18612-29202 5193 1004897 A ATOM 2766 CA GLY A 348 -47700 -24287 3073 10018764 A ATOM 2682 N THR A 337 -20331-30659 4989 1004772 A ATOM 2767 C GLY A 348 -46908-23911 1836 10018460 A ATOM 2683 CA THR A 337 -20751-30275 3655 1005118 A ATOM 2768 O GLY A 348 -46383 -247Sl 1141 10017961 A ATOM 2684 CB THR A 337 20890-31494 2754 10011185 A ATOM 2769 N ASN A 349 -46812-22615 1558 10020072 A ATOM 2685 OGl THR A 337 -19593-32000 2442 1006274 A ATOM 2770 CA ASN A 349 -46085 -22152 0385 10020062 A ATOM 2686 CG2 THR A 337 -21622-31139 1483 1006274 A ATOM 2771 CB ASN A 349 -45987-20620 0393 10011915 A ATOM 2687 C THR A 337 -22130 -29694 3871 1005875 A ATOM 2772 CG ASN A 349 -45821 -20047 1786 10010433 A ATOM 2688 O THR A 337 -22953-30314 4535 1005013 A ATOM 2773 ODl ASN A 349 46693-20191 2645 10010433 A ATOM 2689 N VAL A 338 -22397-28517 3325 1006111 A ATOM 2774 ND2 ASN A 349 -44698-19387 2016 10010433 A ATOM 2690 CA VALA 338 23705 -27923 3529 1006797 A ATOM 2775 C ASN A 349 -44700 -22783 0210 10020072 A ATOM 2691 CB VAL A 338 -23602 -26576 4283 1004143 A ATOM 2776 O ASN A 349 44565 -23770 -0516 10020072 A ATOM 2692 CGl VAL A 338 -24988 -26094 4702 1004105 A ATOM 2777 N MET A 350 -43681 -22239 0874 1009070 A ATOM 2693 CG2VALA338 -22686-26724 5481 1004105 A ATOM 2778 CA META 350 -42324-22771 0735 1008679 A ATOM 2694 C VAL A 338 -24418-27694 2217 1007244 A ATOM 2779 CB META 350 -41432-21713 0083 10016592 A ATOM 2695 O VAL A 338 -23792-27421 1 187 1007227 A ATOM 2780 CG MET A 350 -39993 -22142 -0109 10012060 A ATOM 2696 N LYS A 339 -25736 -27825 2269 1004406 A ATOM 2781 SD MET A 350 -39026-20915 -0987 10012060 A ATOM 2697 CA LYS A 339 -26598 27616 1114 1004194 A ATOM 2782 CE META 350 -38974 -21657 -2652 10012060 A ATOM 2698 CB LYS A 339 -26729-28909 0311 10017542 A ATOM 2783 C MET A 350 -41667-23271 2030 1008393 A ATOM 2699 CG LYS A 339 -25419 -29370 -0311 10014373 A ATOM 2784 O MET A 350 -42023-22848 3131 1008036 A ATOM 2700 CD LYS A 339 25329-30883 -0385 10014373 A ATOM 2785 N THR A 351 -40702-24181 1878 1009862 A ATOM 2701 CE LYS A 339 -23948-31323 -0851 10014373 A ATOM 2786 CA THR A 351 -39972 -24749 3011 1009658 A ATOM 2702 NZ LYS A 339 -23758-32793 -0716 10014373 A ATOM 2787 CB THR A 351 -40475 -26185 3348 10010087 A ATOM 2703 C LYS A 339 -27952-27187 1657 1005093 A ATOM 2788 OGl THR A 351 -40413 26385 4760 1006799 A ATOM 2704 O LYS A 339 -28451 -27788 2605 1004359 A ATOM 2789 CG2THRA351 -39611 -27261 2669 1006799 A ATOM 2705 N VAL A 340 -28525-26132 1088 1006142 A ATOM 2790 C THRA 351 -38470-24805 2710 1009081 A ATOM 2706 CA VAL A 340 -29830-25654 1531 1005885 A ATOM 2791 O THRA 351 38052 -25220 1626 1008240 A ATOM 2707 CB VALA 340 -29849-24137 1754 1006062 A ATOM 2792 N LEU A 352 37657 24379 3670 1006155 A ATOM 2708 CGl VAL A 340 -31237-23712 2201 1004608 A ATOM 2793 CA LEU A 352 -36214-24400 3489 1006457 A ATOM 2709 CG2 VAL A 340 -28810-23738 2788 1004608 A ATOM 2794 CB LEU A 352 -35625-23021 3768 1008116 A ATOM 2710 C VAL A 340 -30832-25964 0433 1006142 A ATOM 2795 CG LEU A 352 35819 -22080 2582 1006222 A ATOM 2711 O VAL A 340 -30653 -25539 -0693 1005827 A ATOM 2796 CDl LEUA 352 -35500 -20660 2972 1006222 A ATOM 2712 N THR A 341 -31893-26692 0752 1006419 A ATOM 2797 CD2LEUA352 34927 -22545 1444 1006222 A ATOM 2713 CA THR A 341 -32886 -27037 -0257 1006009 A ATOM 2798 C LEU A 352 -35580-25444 4387 1006125 A ATOM 2714 CB THR A 341 -33136-28535 -0285 1007990 A ATOM 2799 O LEU A 352 -35941 -25580 5556 1005687 A ATOM 2715 OGl THR A 341 -31916-29215 -0600 1006126 A ATOM 2800 N GLU A 353 -34640-26192 3827 1006727 A ATOM 2716 CG2THRA341 -34175 -28865 -1330 1006126 A ATOM 2801 CA GLU A 353 -33971-27239 4566 1006352 A ATOM 2717 C THRA 341 -34215-26336 -0052 006224 A ATOM 2802 CB GLU A 353 -34405-28596 4035 10016460 A ATOM 2718 O THR A 341 -34651 -26121 1078 006384 A ATOM 2803 CG GLU A 353 -33778-29754 4758 10012315 A ATOM 2719 N GLY A 342 -34860 25977 -1 155 0011498 A ATOM 2804 CD GLU A 353 -34169 -31073 4146 10012315 A ATOM 2720 CA GLY A 342 -36132-25294 -1059 10011915 A ATOM 2805 OEl GLU A 353 -35385-31339 4052 10012315 A ATOM 2721 C GLY A 342 -37307-26159 -1459 10011812 A ATOM 2806 OE2GLUA353 -33264-31843 3756 10012315 A ATOM 2722 O GLY A 342 -37978 25873 2449 10011239 A ATOM 2807 C GLU A 353 -32466-27114 4450 1006677 A ATOM 2723 N ASN A 343 -37559 -27217 -0694 1009959 A ATOM 2808 O GLU A 353 -31899-27265 3363 1006755 A ATOM 2724 CA ASN A 343 -38678-28118 -0975 10010600 A ATOM 2809 N CYS A 354 -31825-26848 5585 1006481 A ATOM 2725 CB ASN A 343 -38617 -29350 -0067 10017657 A ATOM 2810 CA CYS A 354 -30375 -26708 5659 1006509 A ATOM 2726 CG ASN A 343 -37275-30048 -0117 10015637 A ATOM 2811 C CYS A 354 -29843-28043 6145 1006618 A ATOM 2727 ODl ASN A 343 -36857-30541 -1165 10015637 A ATOM 2812 O CYS A 354 -30235 -28501 7207 1006488 A ATOM 2728 ND2ASNA343 -36589-30091 1021 10015637 A ATOM 2813 CB CYS A 354 -30019-25616 6666 10010751 A ATOM 2729 C ASN A 343 -39967-27361 -0699 10010406 A ATOM 2814 SG CYS A 354 -28312 24997 6614 1008470 A ATOM 2730 O ASN A 343 -39960 -26139 -0569 1009269 A ATOM 2815 N THR A 355 -28979-28689 5370 1007513 A ATOM 2731 N GLU A 344 -41075 -28086 -0611 10017422 A ATOM 2816 CA THR A 355 -28433-29962 5816 1006449 A ATOM 2732 CA GLU A 344 -42364 -27466 -0325 10017422 A ATOM 2817 CB THR A 355 28833-31125 4903 10011637 A ATOM 2733 CB GLU A 344 -42891 -26728 -1560 10013888 A ATOM 2818 OGl THR A 355 -27751-31418 4016 1006552 A ATOM 2734 CG GLU A 344 -42410-25287 -1613 10011878 A ATOM 2819 CG2THRA355 -30068 -30777 4099 1006552 A ATOM 2735 CD GLU A 344 -42761-24574 -2900 10011878 A ATOM 2820 C THR A 355 -26917-29893 5870 1007798 A ATOM 2736 OEl GLU A 344 -42123 -24862 -3935 10011878 A ATOM 2821 O THR A 355 -26249 -29529 4892 1007078 A ATOM 2737 OE2GLUA344 -43674 -23723 -2874 10011878 A ATOM 2822 N VAL A 356 -26389-30246 7034 1004417 A ATOM 2738 C GLU A 344 -43364-28497 0176 10017422 A ATOM 2823 CA VAL A 356 -24956 -30236 7283 1003989 A ATOM 2739 O GLU A 344 -43840-29345 -0580 10017422 A ATOM 2824 CB VAL A 356 -24656 -29473 8599 1005096 A ATOM 2740 N LEU A 345 -43673 -28403 I 469 10020084 A ATOM 2825 CGl VAL A 356 -23160-29221 8735 1003549 A ATOM 2741 CA LEU A 345 -44580-29326 2152 10020084 A ATOM 2826 CG2VALA356 -25429-28163 8613 1003549 A ATOM 2742 CB LEU A 345 -44381-29210 3675 10017620 A ATOM 2827 C VAL A 356 -24492 -31690 7367 1004873 A ATOM 2743 CG LEU A 345 -42987-29532 4243 10012899 A ATOM 2828 O VALA 356 -24952-32444 8210 1004984 A ATOM 2744 CDl LEUA 345 -43002-29411 5762 10012899 A ATOM 2829 N ASN A 357 -23571 -32069 6488 1005595 A ATOM 2745 CD2LEUA345 -42574-30935 3836 10012899 A ATOM 2830 CA ASN A 357 -23102 33443 6426 1005217 A ATOM 2746 C LEU A 345 -46078-29245 1816 10020084 A ATOM 2831 CB ASN A 357 -23134-33924 4984 10013575 A ATOM 2747 O LEU A 345 -46926 -29474 2679 10020084 A ATOM 2832 CG ASN A 357 -24526 -33958 4434 1008967 A ATOM 2748 N GLU A 346 -46390-28918 0565 10018727 A ATOM 2833 ODl ASN A 357 25415-34565 5030 1008967 A ATOM 2749 CA GLU A 346 -47769 -28859 0066 10018727 A ATOM 2834 ND2 ASN A 357 -24736 -33298 3297 1008967 A ATOM 2750 CB GLU A 346 -48390-30256 0173 10015773 A ATOM 2835 C ASN A 357 -21752-33772 7009 1005633 A ATOM 2751 CG GLU A 346 -47424-31356 -0261 10014316 A ATOM 2836 O ASN A 357 -20726-33162 6674 1005921 A ATOM 2752 CD GLU A 346 -48110-32660 -0618 10014316 A ATOM 2837 N SER A 358 -21791-34791 7864 1003836 A ATOM 2753 OEl GLU A 346 -48855 -32682 -1622 10014316 A ATOM 2838 CA SER A 358 -20647 -35340 8576 1004566 A ATOM 2754 OE2GLUA346 -47901 -33662 0102 10014316 A ATOM 2839 CB SERA 358 -20020 -36475 7758 1006365 A 65251/C766

ATOM 2840 OG SERA 358 19433-35985 6576 1006199 A ATOM 2925 CE3TRPA368 -32816-20723 6696 1005797 A ATOM 2S41 C SERA 358 -19579-34337 9020 1005038 A ATOM 2926 CDl TRP A 368 -32956-21510 10229 1005797 A ATOM 2842 O SER A 358 -18615-34053 8304 1004593 A ATOM 2927 NEl TRP A 368 -32771 -22732 9627 1005797 A ATOM 2843 N PHE A 359 -19783 -33822 10234 1003462 A ATOM 2928 CZ2TRPA368 -32523 23492 7241 1005797 A ATOM 2844 CA PHEA 359 -18890-32859 10901 1002893 A ATOM 2929 CZ3 TRP A 368 -32637-21654 5674 1005797 A ATOM 2845 CB PHE A 359 -19654-31568 11161 1005107 A ATOM 2930 CH2 TRP A 368 -32493 -23023 5955 1005797 A ATOM 2846 CG PHEA 359 -21009-31785 11754 1004567 A ATOM 2931 C TRP A 368 -31984-16858 9654 1005138 A ATOM 2847 CDl PHE A 359 -21 163-31951 13128 1004567 A ATOM 2932 O TRP A 368 -32695-16302 10495 1005157 A ATOM 2848 CD2PHEA359 -22144-31781 10943 1004567 A ATOM 2933 N ILE A 369 -31337-16203 8594 1005814 A ATOM 2849 CEl PHE A 359 -22436-32103 13696 1004567 A ATOM 2934 CA ILE A 369 -31403-14752 8577 1005951 A ATOM 2850 CE2 PHE A 359 -23425-31931 Il 492 1004567 A ATOM 2935 CB ILE A 369 -30031 -14142 8879 1005811 A ATOM 2851 CZ PHE A 359 -23572 -32090 12873 1004567 A ATOM 2936 CG2 ILE A 369 -30113-12649 8829 1003579 A ATOM 2852 C PHE A 359 -18455 33493 12227 1003552 A ATOM 2937 CGl ILE A 369 -29551-14606 10257 1003579 A ATOM 2853 O PHE A 359 -19260-34203 12835 1003307 A ATOM 2938 CDl ILE A 369 -28145-14203 10577 1003579 A ATOM 2854 N TYR A 360 -17219-33274 12692 1009031 A ATOM 2939 C ILE A 369 -31840-14304 7187 1006133 A ATOM 2855 CA TYRA 360 16905-33946 13931 1009009 A ATOM 2940 O ILE A 369 -31345-14815 6181 1005813 A ATOM 2856 CB TYRA 360 -15431-34250 14180 10015730 A ATOM 2941 N GLU A 370 -32768-13354 7127 1005739 A ATOM 2857 CG TYRA 360 15324-34757 15620 1004444 A ATOM 2942 CA GLU A 370 -33234-12856 5841 1006004 A ATOM 2858 CDl TYR A 360 -16237-35721 16108 1004444 A ATOM 2943 CB GLU A 370 -34318-11805 6056 10011915 A ATOM 2859 CEl TYRA 360 -16286-36071 17470 1004444 A ATOM 2944 CG GLU A 370 -35654 12433 6409 1009779 A ATOM 2860 CD2 TYR A 360 -14444-34170 16540 1004444 A ATOM 2945 CD GLU A 370 -36680-11427 6882 1009779 A ATOM 2861 CE2TYRA360 -14485-34523 17913 1004444 A ATOM 2946 OEl GLU A 370 -36853-10386 6211 1009779 A ATOM 2862 CZ TYR A 360 -15411 -35470 18363 1004444 A ATOM 2947 OE2 GLU A 370 37325-11682 7923 1009779 A ATOM 2863 OH TYR A 360 -15454-35811 19698 1004444 A ATOM 2948 C GLU A 370 -32032-12288 5090 1006022 A ATOM 2864 C TYR A 360 -17417-33368 15210 1009118 A ATOM 2949 O GLU A 370 -31247-11528 5657 1005907 A ATOM 2865 O TYR A 360 -18431 -33836 15697 1009711 A ATOM 2950 N SER A 371 -31 884-12669 3822 1006772 A ATOM 2866 N PRO A 361 -16721 -32380 15802 1006194 A ATOM 2951 CA SER A 371 -30749-12228 3005 1006826 A ATOM 2867 CD PRO A 361 -15850-31365 15189 1003116 A ATOM 2952 CB SER A 371 -30831 -12857 1616 1007306 A ATOM 2868 CA PRO A 361 -17322-31913 17067 1005753 A ATOM 2953 OG SER A 371 -32040-12499 0982 1006214 A ATOM 2869 CB PRO A 361 -16603-30603 17342 1003040 A ATOM 2954 C SER A 371 -30547-10718 2862 1006753 A ATOM 2870 CG PRO A 361 -16230-30116 15972 1003116 A ATOM 2955 O SER A 371 -29433-10264 2581 1006847 A ATOM 2871 C PRO A 361 -18821 31817 16793 1006493 A ATOM 2956 N GLU A 372 -31612 -9942 3040 1005796 A ATOM 2872 O PRO A 361 -19267-31039 15958 1006210 A ATOM 2957 CA GLU A 372 -31 503 -8490 2930 1005651 A ATOM 2873 N PRO A 362 -19610-32683 17453 1004590 A ATOM 2958 CB GLU A 372 -32838 -7824 3264 10010579 A ATOM 2874 CD PRO A 362 19100 33574 18513 1003537 A ATOM 2959 CG GLU A 372 -33351 -8161 4647 10010579 A ATOM 2875 CA PRO A 362 -21070-32794 17324 1003961 A ATOM 2960 CD GLU A 372 -34483 -7256 5091 10010579 A ATOM 2876 CB PRO A 362 -21416-33969 18239 1003537 A ATOM 2961 OEl GLU A 372 -34240 -6038 5227 10010579 A ATOM 2877 CG PRO A 362 -20346-33917 19272 1003537 A ATOM 2962 OE2GLUA372 -35611 -7760 5308 10010579 A ATOM 2878 C PRO A 362 -21936-31583 17567 1004221 A ATOM 2963 C GLU A 372 -30426 -7969 3883 1006112 A ATOM 2879 O PRO A 362 -23109-31577 17185 1004697 A ATOM 2964 O GLU A 372 -29654 -7071 3545 1006219 A ATOM 2880 N ASP A 363 -21372-30560 18199 1004085 A ATOM 2965 N HIS A 373 -30373 -8554 5072 1006093 A ATOM 2881 CA ASP A 363 -22116-29336 18453 1004070 A ATOM 2966 CA HIS A 373 -29417 -8149 6090 1006442 A ATOM 2882 CB ASP A 363 -21479-28533 19604 1007034 A ATOM 2967 CB HIS A 373 -29733 -8862 7392 I 009769 A ATOM 2883 CG ASP A 363 -19959-28380 19470 1006455 A ATOM 2968 CG HIS A 373 -31083 -8531 7928 1006704 A ATOM 2884 ODl ASP A 363 -19248-29410 19399 1006455 A ATOM 2969 CD2 HIS A 373 32124 -9322 8278 1006704 A ATOM 2885 OD2ASPA363 -19473-27225 19458 1006455 A ATOM 2970 NDl HIS A 373 -31486 -7235 8163 1006704 A ATOM 2886 C ASP A 363 -22188-28484 17191 1004424 A ATOM 2971 CEl HIS A 373 -32719 -7241 8638 1006704 A ATOM 2887 O ASP A 363 -21167-28128 16592 1004074 A ATOM 2972 NE2 HIS A 373 -33130 -8495 8717 1006704 A ATOM 2888 N VAL A 364 -23407-28174 16775 1004177 A ATOM 2973 C HIS A 373 -27950 -8356 5744 1006019 A ATOM 2889 CA VALA 364 -23619-27351 15597 1004409 A ATOM 2974 O HIS A 373 -27072 -7904 6476 1005603 A ATOM 2890 CB VAL A 364 -23912-28189 14335 1006102 A ATOM 2975 N PHE A 374 -27669 -9041 4647 1005221 A ATOM 2891 CGl VAL A 364 -24592-27338 13290 1003941 A ATOM 2976 CA PHE A 374 -26279 -9240 4278 1005298 A ATOM 2892 CG2VALA364 -22623-28706 13763 1003941 A ATOM 2977 CB PHE A 374 -26054-10665 3780 1007624 A ATOM 2893 C VAL A 364 -24814-26490 15879 1005143 A ATOM 2978 CG PHE A 374 -26087-11680 4873 1005642 A ATOM 2894 O VAL A 364 -25766-26925 16519 1004317 A ATOM 2979 CDl PHE A 374 -27296-12173 5350 1005642 A ATOM 2895 N ILE A 365 -24750 -25251 15426 1005302 A ATOM 2980 CD2 PHE A 374 -24909 -12090 5486 1005642 A ATOM 2896 CA ILE A 365 -25863-24354 15611 1004707 A ATOM 2981 CEl PHE A 374 -27334-13055 6424 1005642 A ATOM 2897 CB ILE A 365 -25601 -23312 16700 1007393 A ATOM 2982 CE2PHEA374 -24935-12965 6557 1005642 A ATOM 2898 CG2ILEA365 -26725-22297 16717 1005037 A ATOM 2983 CZ PHE A 374 -26154-13449 7027 1005642 A ATOM 2899 CGl ILE A 365 -25527-24014 18059 1005037 A ATOM 2984 C PHE A 374 -25827 -8228 3235 1004906 A ATOM 2900 CDl ILE A 365 -25264-23099 19222 1005037 A ATOM 2985 O PHE A 374 -24734 -8345 2676 1004730 A ATOM 2901 C ILE A 365 -26145 -23687 14296 1005383 A ATOM 2986 N LYS A 375 -26671 -7226 2998 1007142 A ATOM 2902 O ILE A 365 -25242-23391 13514 1005460 A ATOM 2987 CA LYS A 375 -26391 -6175 2027 1007405 A ATOM 2903 N THR A 366 -27423-23451 14070 1003652 A ATOM 2988 CB LYS A 375 25816 -4945 2734 10012177 A ATOM 2904 CA THR A 366 -27890 -22880 12838 1004480 A ATOM 2989 CG LYS A 375 -26842 -4047 3412 1009561 A ATOM 2905 CB THR A 366 -28689 -23953 12087 1005745 A ATOM 2990 CD LYS A 375 -27460 -4687 4643 1009561 A ATOM 2906 OGl THR A 366 -28095-24168 10816 1004513 A ATOM 2991 CE LYS A 375 -28411 -3715 5355 1009561 A ATOM 2907 CG2THRA366 -30131 -23555 II 915 1004513 A ATOM 2992 NZ LYS A 375 -29075 -4316 6554 1009561 A ATOM 2908 C THRA 366 -28747-21646 13059 1005378 A ATOM 2993 C LYS A 375 -25450 -6591 0892 1007907 A ATOM 2909 O THR A 366 -29617-21623 13942 1005302 A ATOM 2994 O LYS A 375 -24417 -5961 0679 1008133 A ATOM 2910 N LYS A 367 -28487-20623 12247 1004612 A ATOM 2995 N GLY A 376 -25794 -7657 0174 1006739 A ATOM 2911 CA LYS A 367 -29249-19373 12295 1004932 A ATOM 2996 CA GLY A 376 -24962 -8088 -0937 1006739 A ATOM 2912 CB LYS A 367 28372-18198 12754 1005737 A ATOM 2997 C GLY A 376 -23766 -8979 -0653 1006739 A ATOM 2913 CG LYS A 367 -28012-18227 14210 1004838 A ATOM 2998 O GLY A 376 -23393 -9780 -1507 1006739 A ATOM 2914 CD LYS A 367 -27383-16938 14673 1004838 A ATOM 2999 N GLU A 377 -23147 -8843 0517 1007980 A ATOM 2915 CE LYS A 367 -27231 -16964 16188 1004838 A ATOM 3000 CA GLU A 377 -21994 -9671 0859 1007980 A ATOM 2916 NZ LYS A 367 -26923-15621 16766 1004838 A ATOM 3001 CB GLU A 377 -20909 -8827 1523 10010270 A ATOM 2917 C LYS A 367 -29828-19045 10925 1005202 A ATOM 3002 CG GLU A 377 -19584 -9546 1673 10010270 A ATOM 2918 O LYS A 367 -29123-19072 9917 1005233 A ATOM 3003 CD GLU A 377 -18513 -8668 2290 10010270 A ATOM 2919 N TRP A 368 -31121-18751 10902 1004937 A ATOM 3004 OEl GLU A 377 -17343 9109 2322 10010270 A ATOM 2920 CA TRP A 368 -31795-18371 9665 1004943 A ATOM 3005 OE2GLUA377 -18842 -7544 2743 10010270 A ATOM 2921 CB TRP A 368 -33150-19074 9534 1007805 A ATOM 3006 C GLU A 377 -22437-10771 1809 1007980 A ATOM 2922 CG TRP A 368 -33012-20530 9290 1005797 A ATOM 3007 O GLU A 377 -22900-10491 2922 1007980 A ATOM 2923 CD2TRPA368 -32851 -21176 8020 1005797 A ATOM 3008 N TYR A 378 -22300-12022 1373 1005539 A ATOM 2924 CE2TRPA368 -32702 -22556 8270 1005797 A ATOM 3009 CA TYR A 378 -22703-13162 2204 1005539 A 65251/C766

ATOM 3010 CB TYR A 378 -23253 -14275 1319 1007789 A ATOM 3095 N PRO A 387 -31072 -9626 12887 1006030 A

ATOM 3011 CG TYR A 378 -24570-13897 0701 I 007789 A ATOM 3096 CD PRO A 387 -31253 -8503 11954 1007761 A

ATOM 3012 CDl TYR A 378 -24631 -13320 -0566 1007789 A ATOM 3097 CA PRO A 387 -32367-10122 13379 1006030 A

ATOM 3013 CEl TYR A 378 -25847-12889 -1 102 1007789 A ATOM 3098 CB PRO A 387 -33366 -9325 12555 1007761 A

ATOM 3014 CD2 TYR A 378 -25754-14040 1416 1007789 A ATOM 3099 CG PRO A 387 -32636 -8032 12305 1007761 A

ATOM 3015 CE2TYRA378 -26968-13614 0893 1007789 A ATOM 3100 C PRO A 387 -32309-11597 12950 1006030 A

ATOM 3016 CZ TYR A 378 27010 13037 0362 1007789 A ATOM 3101 O PRO A 387 -31731 -11885 11892 1006030 A

ATOM 3017 OH TYR A 378 -28206-12577 -0859 1007789 A ATOM 3102 N GLU A 388 -32884-12538 13696 1009002 A

ATOM 3018 C TYR A 378 -21647-13730 3159 1 005539 A ATOM 3103 CA GLU A 388 -32691-13907 13244 1009002 A

ATOM 3019 O TYR A 378 -21184-14862 3002 1 005539 A ATOM 3104 CB GLU A 388 -31507-14505 14002 10014571 A

ATOM 3020 N LYS A 379 -21276-12910 4140 1005186 A ATOM 3105 CG GLU A 388 -31766-14748 15469 10014571 A

ATOM 3021 CA LYS A 379 -20315-13253 5179 1005186 A ATOM 3106 CD GLU A 388 -30683-15590 16103 10014571 A

ATOM 3022 CB LYS A 379 -18986-12518 4982 007955 A ATOM 3107 OEl GLU A 388 -30463-16723 15624 10014571 A

ATOM 3023 CG LYS A 379 18199-12955 3761 1007955 A ATOM 3108 OE2GLUA388 -30053 15123 17076 10014571 A

ATOM 3024 CD LYS A 379 -16913-12143 3631 1007955 A ATOM 3109 C GLU A 388 -33755-14993 13140 1009002 A

ATOM 3025 CE LYS A 379 -16187-12413 2309 007955 A ATOM 3110 O GLUA388 -33392-16164 13088 1009002 A

ATOM 3026 NZ LYS A 379 -15028-11485 2126 007955 A ATOM 3111 N TRPA389 35040-14672 13092 1008689 A

ATOM 3027 C LYS A 379 -20964-12802 6478 1 005186 A ATOM 3112 CA TRPA389 -36025-15753 12960 1008689 A

ATOM 3028 O LYS A 379 -21595-11746 6534 1005186 A ATOM 3113 CB TRP A 389 -35894-16421 11584 10012030 A

ATOM 3029 N TYR A 380 -20851 -13623 7511 1 004161 A ATOM 3114 CG TRPA389 -36839-15943 10529 10012030 A

ATOM 3030 CA TYRA 380 -21412-13279 8812 1004161 A ATOM 3115 CD2TRPA389 -37961 -15063 10700 10012030 A

ATOM 3031 CB TYR A 380 -21767 -14555 9566 1004519 A ATOM 3116 CE2TRPA389 -38579-14928 9436 10012030 A

ATOM 3032 CG TYR A 380 -22458 -14322 10875 1004519 A ATOM 3117 CE3TRPA389 -38508-14377 11798 10012030 A

ATOM 3033 CDl TYR A 380 -23840-14150 10929 1004519 A ATOM 3118 CD1TRPA389 -36825-16292 9207 10012030 A

ATOM 3034 CEl TYR A 380 -24493-13930 12154 1004519 A ATOM 3119 NEl TRP A 389 -37865-15688 8545 10012030 A

ATOM 3035 CD2 TYR A 380 -21731 14265 12070 1004519 A ATOM 3120 CZ2TRPA389 -39718-14133 9239 10012030 A

ATOM 3036 CE2TYRA380 -22365 -14042 13294 1004519 A ATOM 3121 CZ3TRPA389 -39640-13588 11602 10012030 A

ATOM 3037 CZ TYR A 380 -23746 -13878 13332 1004519 A ATOM 3122 CH2TRPA389 -40231-13474 10331 10012030 A

ATOM 3038 OH TYR A 380 -24386-13691 14537 1004519 A ATOM 3123 C TRP A 389 -35830-16834 14025 1008689 A

ATOM 3039 C TYR A 380 -20321 -12503 9569 1004161 A ATOM 3124 O TRP A 389 -35380-17935 13708 1008689 A

ATOM 3040 O TYR A 380 -19291 -13073 9914 1 004161 A ATOM 3125 N GLY A 390 -36168-16535 15276 1006769 A

ATOM 3041 N VAL A 381 -20534-11209 9800 004885 A ATOM 3126 CA GLY A 390 -35996-17517 16332 1006769 A

ATOM 3042 CA VALA 381 -19547-10391 10502 1004885 A ATOM 3127 C GLY A 390 36844 18769 16173 1006769 A

ATOM 3043 CB VAL A 381 -19708 -8910 10134 1005885 A ATOM 3128 O GLY A 390 -37884-18738 15515 1006769 A

ATOM 3044 CGl VAL A 381 -18612 -8090 10784 1005885 A ATOM 3129 N ARG A 391 -36388-19876 16761 1008078 A

ATOM 3045 CG2VALA381 -19668 -8755 8628 1005885 A ATOM 3130 CA ARG A 391 -37113-21146 16708 1008078 A

ATOM 3046 C VAL A 381 -19688-10558 12014 1004885 A ATOM 3131 CB ARG A 391 -36124-22323 16715 1009291 A

ATOM 3047 O VAL A 381 -20750-10278 12582 1004885 A ATOM 3132 CG ARG A 391 -35131 -22323 15543 1009291 A

ATOM 3048 N ASN A 382 -18605-10987 12654 1008289 A ATOM 3133 CD ARG A 391 -35577-23210 14362 1009291 A

ATOM 3049 CA ASN A 382 -18609-11247 14082 1008289 A ATOM 3134 NE ARG A 391 -35085 -24590 14458 1009291 A

ATOM 3050 CB ASN A 382 -17193-11275 14627 1005229 A ATOM 3135 CZ ARG A 391 -35592-25535 15256 1009291 A

ATOM 3051 CG ASN A 382 -17074-12132 15892 1005229 A ATOM 3136 NHl ARG A 391 -36628-25269 16045 1009291 A

ATOM 3052 ODl ASN A 382 -18008-1222C 16703 1005229 A ATOM 3137 NH2ARGA391 -35054-26750 15271 1009291 A

ATOM 3053 ND2 ASN A 382 -15918 -12754 16069 1005229 A ATOM 3138 C ARG A 391 -37996-21177 17955 1008078 A

ATOM 3054 C ASN A 382 -19442-10320 14955 008289 A ATOM 3139 O ARG A 391 -37832 -20346 18844 1008078 A

ATOM 3055 O ASN A 382 -20564 -10666 15361 1008289 A ATOM 3140 N LYS A 392 -38938-22111 18022 1008560 A

ATOM 3056 N GLY A 383 -18913 -9144 5256 004080 A ATOM 3141 CA LYS A 392 -39815-22193 19191 1008560 A

ATOM 3057 CA GLY A 383 19667 8261 16130 1004080 A ATOM 3142 CB LYS A 392 -41287-22188 18765 10011561 A

ATOM 3058 C GLY A 383 -20929 -7605 5588 1 004080 A ATOM 3143 CG LYS A 392 -42256-22271 19932 10011561 A

ATOM 3059 O GLY A 383 -21559 -6819 6293 004080 A ATOM 3144 CD LYS A 392 -43683-22497 19467 10011561 A

ATOM 3060 N ARG A 384 -21320 -7913 4358 004479 A ATOM 3145 CE LYS A 392 -44609-22743 20656 10011561 A

ATOM 3061 CA ARG A 384 -22498 -7279 13780 1004479 A ATOM 3146 NZ LYS A 392 -45984-2314620237 10011561 A

ATOM 3062 CB ARG A 384 -22444 -7408 12268 1005807 A ATOM 3147 C LYS A 392 -39528-2344920012 1008560 A

ATOM 3063 CG ARG A 384 -23501 -6609 11541 1005807 A ATOM 3148 O LYS A 392 -39740-24568 19543 1008560 A

ATOM 3064 CD ARG A 384 -23134 -6510 10077 1005807 A ATOM 3149 N SERA 393 39047-23257 21238 1005225 A

ATOM 3065 NE ARG A 384 -21847 -5850 9920 1005807 A ATOM 3150 CA SER A 393 -38724 -2437422124 1005225 A

ATOM 3066 CZ ARG A 384 -21187 -5751 8770 005807 A ATOM 3151 CB SER A 393 -37406 -25035 21693 1006214 A

ATOM 3067 NHl ARG A 384 -21691 -6276 7668 1005807 A ATOM 3152 OG SER A 393 -37045 -26085 22570 1006214 A

ATOM 3068 NH2ARGA384 -20021 -5117 8714 1005807 A ATOM 3153 C SER A 393 -38597 -23873 23547 1005225 A

ATOM 3069 C ARG A 384 -23818 -7807 4285 004479 A ATOM 3154 O SER A 393 -38370 -22692 23758 1005225 A

ATOM 3070 O ARG A 384 -23924 -8984 4619 004479 A ATOM 3155 N ASN A 394 -38763 -2476024523 1006820 A

ATOM 3071 N TYR A 385 -24823 -6939 4347 005608 A ATOM 3156 CA ASN A 394 -38628 -2435925918 1006820 A

ATOM 3072 CA TYR A 385 -26146 -7343 14801 1005608 A ATOM 3157 CB ASN A 394 -39246-25398 26840 1007151 A

ATOM 3073 CB TYR A 385 -26897 6147 15380 1006399 A ATOM 3158 CG ASN A 394 -40739 -25409 26760 1007151 A

ATOM 3074 CG TYRA 385 -28339 -6465 15676 1006399 A ATOM 3159 ODl ASN A 394 41377 -2436326856 1007151 A

ATOM 3075 CDl TYR A 385 -28692 -7230 16788 1006399 A ATOM 3160 ND2ASNA394 -41316-2659426590 1007151 A

ATOM 3076 CEl TYRA 385 30013 7592 17022 1006399 A ATOM 3161 C ASN A 394 -37152 -24199 26246 1006820 A

ATOM 3077 CD2TYRA385 -29346 -6066 14806 1006399 A ATOM 3162 O ASN A 394 -36779 -23571 27237 1006820 A

ATOM 3078 CE2 TYRA 385 -30669 -6421 15024 1006399 A ATOM 3163 N TYR A 395 -36317-2478025398 1004239 A

ATOM 3079 CZ TYR A 385 -30999 -7182 16130 1006399 A ATOM 3164 CA TYRA395 -34885 -24705 25569 1004239 A

ATOM 3080 OH TYRA 385 -32318 -7532 16337 1006399 A ATOM 3165 CB TYRA395 -34239 -2604425190 1005181 A

ATOM 3081 C TYRA 385 -26966 -7930 3644 1 005608 A ATOM 3166 CG TYR A 395 -34626 -2719626075 1005181 A

ATOM 3082 O TYR A 385 -26867 -7448 2516 005608 A ATOM 3167 CDl TYR A 395 -35676 -2803625734 1005181 A

ATOM 3083 N TYR A 386 -27770 -8961 3919 006796 A ATOM 3168 CEl TYR A 395 -36052 -29098 26567 1005181 A

ATOM 3084 CA TYR A 386 -28618 -9570 12891 1006796 A ATOM 3169 CD2TYRA395 -33951-2743627272 1005181 A

ATOM 3085 CB TYR A 386 -27959-10791 12241 1004487 A ATOM 3170 CE2TYRA395 -34318-28489 28111 1005181 A

ATOM 3086 CG TYR A 386 -26677-10567 11478 1004487 A ATOM 3171 CZ TYRA395 -35372-2931427748 1005181 A

ATOM 3087 CDl TYRA 386 -25435-1077C 12084 1004487 A ATOM 3172 OH TYR A 395 -35750-3034228573 1005181 A

ATOM 3088 CEl TYR A 386 -24244-10620 11366 1004487 A ATOM 3173 C TYR A 395 -34333 -23607 24663 1004239 A

ATOM 3089 CD2 TYRA 386 -26699 -1019C 10138 1004487 A ATOM 3174 O TYR A 395 -34947-23271 23652 1004239 A

ATOM 3090 CE2 TYRA 386 -25515-10022 9414 1004487 A ATOM 3175 N GLU A 396 -33177 -2305425029 1004924 A

ATOM 3091 CZ TYR A 386 -24291-10243 10035 1004487 A ATOM 3176 CA GLU A 396 -32517-22025 24232 1004924 A

ATOM 3092 OH TYR A 386 23120-10087 9335 1004487 A ATOM 3177 CB GLU A 396 -31944-20941 25134 1009362 A

ATOM 3093 C TYR A 386 -29939-10079 13444 1006796 A ATOM 3178 CG GLU A 396 -32908 -2041526165 1009362 A

ATOM 3094 O TYR A 386 -29951 -10876 14378 1006796 A ATOM 3179 CD GLU A 396 -32219-19539 27195 1009362 A 65251/C766

ATOM 3180 OEl GLU A 396 -31219-1999827796 1009362 A ATOM 3265 CB LYS A 407 -28586-39075 13007 10013914 A ATOM 3181 OE2GLUA396 -32675-1839627411 1009362 A ATOM 3266 CG LYS A 407 -30074-38831 13142 10012524 A ATOM 3182 C GLU A 396 -31369-22725 23513 1004924 A ATOM 3267 CD LYS A 407 -30858-39750 12211 10012524 A ATOM 3183 O GLU A 396 -30709 -23573 24103 1004924 A ATOM 3268 CE LYS A 407 -32348-39435 12227 10012524 A ATOM 3184 N PRO A 397 -31120-22396 22234 1007001 A ATOM 3269 NZ LYS A 407 -32636-38085 11663 10012524 A ATOM 3185 CD PRO A 397 -31727 -21359 21387 1004282 A ATOM 3270 C LYS A 407 26269 38660 13774 1005689 A ATOM 3186 CA PRO A 397 -30014-23060 21531 1007001 A ATOM 3271 O LYS A 407 -25653 -38002 12929 1005583 A ATOM 3187 CB PRO A 397 -29940-22310 20205 1004282 A ATOM 3272 N LYS A 408 -25699-39616 14493 1005927 A ATOM 3188 CG PRO A 397 -30575 -20985 20511 1004282 A ATOM 3273 CA LYS A 408 -24312-39971 14242 1005886 A ATOM 3189 C PRO A 397 -28731 -22965 22350 1007001 A ATOM 3274 CB LYS A 408 -23758^10797 15397 1006276 A ATOM 3190 O PRO A 397 -28394 -21898 22868 1007001 A ATOM 3275 CG LYS A 408 -22283-41059 15270 1006156 A ATOM 3191 N GLY A 398 -28022 -24085 22468 1004561 A ATOM 3276 CD LYS A 408 -21716-41624 16545 1006156 A ATOM 3192 CA GLY A 398 -26820 -2410723280 1004561 A ATOM 3277 CE LYS A 408 -20214-41818 16432 1006156 A ATOM 3193 C GLY A 398 -27024 -25100 24425 1004561 A ATOM 3278 NZ LYS A 408 -19634-42273 17724 1006156 A ATOM 3194 O GLY A 398 26104 25842 24795 1004561 A ATOM 3279 C LYS A 408 -24349-40799 12958 1005899 A ATOM 3195 N GLU A 399 -28231-25113 24990 1004524 A ATOM 3280 O LYS A 408 -24823 41926 12959 1005756 A ATOM 3196 CA GLU A 399 -28570 -26045 26067 1004524 A ATOM 3281 N ASP A 409 -23871 -40245 11853 1009073 A ATOM 3197 CB GLU A 399 -29898 -25648 26739 1004149 A ATOM 3282 CA ASP A 409 -23946-41000 10621 1009091 A ATOM 3198 CG GLU A 399 -29951 -24212 27228 1004149 A ATOM 3283 CB ASP A 409 -23548 -40127 9407 1009550 A ATOM 3199 CD GLU A 399 -31250 -23839 27959 1004149 A ATOM 3284 CG ASP A 409 -22283 -39321 9633 1008832 A ATOM 3200 OEl GLU A 399 -32337 -24196 27471 1004149 A ATOM 3285 ODl ASP A 409 -21286-39894 10113 1008832 A ATOM 3201 OE2GLUA399 -31196-23165 29016 1004149 A ATOM 3286 OD2ASPA409 -22281 38117 9309 1008832 A ATOM 3202 C GLU A 399 -28726 -27413 25402 1004524 A ATOM 3287 C ASP A 409 -23170-42318 10653 1009082 A ATOM 3203 O GLU A 399 -29330-27514 24333 1004524 A ATOM 3288 O ASP A 409 -22346 -42554 11541 1009455 A ATOM 3204 N PRO A 400 -28174-28481 26006 1005438 A ATOM 3289 N LYS A 410 23496-43173 9683 10014287 A ATOM 3205 CD PRO A 400 -27347-2859627219 1004105 A ATOM 3290 CA LYS A 410 -22906 -44494 9492 10014931 A ATOM 3206 CA PRO A 400 28334 -29785 25356 1004946 A ATOM 3291 CB LYS A 410 -22853-44816 7987 10017805 A ATOM 3207 CB PRO A 400 -27629 -3075426316 1008966 A ATOM 3292 CG LYS A 410 -21866-43979 7167 10011750 A ATOM 3208 CG PRO A 400 -27585-30031 27616 1004105 A ATOM 3293 CD LYS A 410 -22341 -42544 6975 10011750 A ATOM 3209 C PRO A 400 -29784 -30167 25054 1004021 A ATOM 3294 CE LYS A 410 -21316-41718 6204 I 0011750 A ATOM 3210 O PRO A 400 -30047 -3099424173 1004042 A ATOM 3295 NZ LYS A 410 -21761 -40309 6013 10011750 A ATOM 3211 N GLY A 401 -30727-29536 25746 1005891 A ATOM 3296 C LYS A 410 -21516-44686 10096 10014813 A ATOM 3212 CA GLYA401 -32126-29844 25517 1005847 A ATOM 3297 O LYS A 410 -20765 -43730 10248 10014766 A ATOM 3213 C GLYA401 32723 29315 24222 1005826 A ATOM 3298 N ASP A 411 -21186-45934 10426 1006358 A ATOM 3214 O GLY A 401 -33846 -29675 23870 1005897 A ATOM 3299 CA ASP A 411 -19892-46304 11003 1006109 A ATOM 3215 N PHE A 402 -31996 -2846423505 1005400 A ATOM 3300 CB ASP A 411 -19407-47634 10425 10015767 A ATOM 3216 CA PHE A 402 -32513-27915 22264 1005400 A ATOM 3301 CG ASP A 411 -19899-48815 11219 10015767 A ATOM 3217 CB PHE A 402 -31627-26784 21771 10015544 A ATOM 3302 ODl ASP A 411 -19735-48804 12459 10015767 ATOM 3218 CG PHE A 402 -32323 -25866 20833 1005377 A A ATOM 3219 CDl PHE A 402 -33249 -24944 21308 1005377 A ATOM 3303 OD2ASPA411 -20443-49756 10611 10015767 ATOM 3220 CD2 PHE A 402 -32114 -25960 19467 1005377 A A ATOM 3221 CEl PHE A 402 -33962 -24130 20432 1005377 A ATOM 3304 C ASP A 411 -18791-45277 10833 1006270 A ATOM 3222 CE2 PHE A 402 -32823-25148 18581 1005377 A ATOM 3305 O ASP A 411 -17944-45397 9940 1006688 A ATOM 3223 CZ PHE A 402 -33750 -24233 19070 1005377 A ATOM 3306 N ALA A 412 -18809^14272 11707 1007894 A ATOM 3224 C PHE A 402 -32602-28997 21191 1005400 A ATOM 3307 CA ALA A 412 -17822-43193 11696 1009196 A ATOM 3225 O PHE A 402 -31628-29711 20936 1005400 A ATOM 3308 CB ALA A 412 -18022-42299 10477 1009581 A ATOM 3226 N PRO A 403 -33770 -2912020537 1007210 A ATOM 3309 C ALA A 412 -17945-42367 12968 1008666 A ATOM 3227 CD PRO A 403 -34949-28281 20783 1004372 A ATOM 3310 O ALA A 412 -18876-42548 13748 1008171 A ATOM 3228 CA PRO A 403 -34057-30099 19481 1007210 A ATOM 3311 N ASNA413 -16999-41461 13174 1006096 A ATOM 3229 CB PRO A 403 -35561-29952 19257 10014855 A ATOM 3312 CA ASN A 413 -17004^0607 14356 1005377 A ATOM 3230 CG PRO A 403 -36046-29243 20471 1004372 A ATOM 3313 CB ASN A413 -15570-40238 14743 1007139 A ATOM 3231 C PRO A 403 -33302-29854 18181 1007210 A ATOM 3314 CG ASN A 413 -14741 -41438 15077 1007139 A ATOM 3232 O PRO A 403 -33675-28982 17398 1007210 A ATOM 3315 ODl ASN A 413 -15209-42347 15760 1007139 A ATOM 3233 N TRP A 404 -32238-30609 17951 I 006041 A ATOM 3316 ND2ASNA413 -13496 -41452 14614 1007139 A ATOM 3234 CA TRP A 404 -31483-30483 16713 1006041 A ATOM 3317 C ASN A 413 -17780-39317 14113 1005835 A ATOM 3235 CB TRP A 404 30011-30131 16978 1005504 A ATOM 3318 O ASN A 413 -18113-38588 15041 1005804 A ATOM 3236 CG TRP A 404 -29746 -28703 17376 1004828 A ATOM 3319 N THRA 414 -18060-39050 12848 1005195 A ATOM 3237 CD2TRPA404 -30001-27522 16600 1004828 A ATOM 3320 CA THR A 414 -18733-37842 12435 1005499 A ATOM 3238 CE2TRPA404 -29553-26422 17360 1004828 A ATOM 3321 CB THR A 414 -18362-37556 10972 10010711 A ATOM 3239 CE3TRPA404 -30565-27288 15339 1004828 A ATOM 3322 OGl THR A 414 -19031 -36377 10542 1007760 A ATOM 3240 CDl TRP A 404 -29177-28278 18534 1004828 A ATOM 3323 CG2THRA414 -18737-38718 10074 1007760 A ATOM 3241 NEl TRP A 404 -29056-26915 18535 1004828 A ATOM 3324 C THRA 414 -20255-37848 12647 1005445 A ATOM 3242 CZ2TRPA404 -29649-25100 16903 1004828 A ATOM 3325 O THR A 414 -20841-38892 12928 1005552 A ATOM 3243 CZ3TRPA404 -30664 -25965 14883 1004828 A ATOM 3326 N TYRA 415 -20875-36668 12557 1004273 A ATOM 3244 CH2TRPA404 -30207 -24892 15667 1004828 A ATOM 3327 CA TYR A 415 -22327 -36507 12733 1004376 A ATOM 3245 C TRP A 404 -31575-31857 16069 1006041 A ATOM 3328 CB TYR A 415 -22658-35755 14021 1007545 A ATOM 3246 O TRP A 404 -31326-32867 16723 1006041 A ATOM 3329 CG TYR A 415 -22299-36470 15288 1004239 A ATOM 3247 N ASN A 405 -31939-31906 14794 1007315 A ATOM 3330 CDl TYRA 415 -20966-36667 15646 1004239 A ATOM 3248 CA ASN A 405 -32045 -33186 14122 10073 IS A ATOM 3331 CEl TYRA 415 -20624-37358 16804 1004239 A ATOM 3249 CB ASN A 405 -32924-33048 12888 1007759 A ATOM 3332 CD2TYRA415 -23286-36976 16120 1004239 A ATOM 3250 CG ASN A 405 -33515-34359 12461 1007759 A ATOM 3333 CE2 TYRA 415 -22959-37668 17281 1004239 A ATOM 3251 ODl ASN A 405 -32817-35246 11972 1007759 A ATOM 3334 CZ TYR A 415 -21629-37856 17616 1004239 A ATOM 3252 ND2 ASN A 405 -34811 -34500 12655 1007759 A ATOM 3335 OH TYR A 415 -21303-38542 18768 1004239 A ATOM 3253 C ASN A 405 -30653 -33682 13745 1008212 A ATOM 3336 C TYR A 415 -22947-35718 11586 1005132 A ATOM 3254 O ASN A 405 -30229-33604 12583 1007518 A ATOM 3337 O TYRA 415 -22247-35023 10843 1004597 A ATOM 3255 N ILE A 406 -29935 -34176 14750 1005966 A ATOM 3338 N SERA416 -24268-35812 11458 1005216 A ATOM 3256 CA ILE A 406 -28589 -34700 14547 1005186 A ATOM 3339 CA SER A 416 -24987-35104 10405 1005011 A ATOM 3257 CB ILE A 406 -27582-34072 15535 1005777 A ATOM 3340 CB SERA 416 -25387 -36058 9275 1007992 A ATOM 3258 CG2 ILE A 406 -26163-34520 15214 1004539 A ATOM 3341 OG SERA416 -24272 -36386 8469 1005630 A ATOM 3259 CGl ILE A 406 -27646-32558 15427 1004539 A ATOM 3342 C SER A 416 -26221 -34427 10977 1005630 A ATOM 3260 CDl ILE A 406 -26615-31843 16275 1004539 A ATOM 3343 O SER A 416 -26807-34899 11950 1005467 A ATOM 3261 C ILE A 406 -28588-36208 14761 1005873 A ATOM 3344 N LEU A 417 -26615-33316 10363 1005266 A ATOM 3262 O ILE A 406 -29267-36711 15646 1005383 A ATOM 3345 CA LEU A 417 -27761 -32545 10820 1005156 A ATOM 3263 N LYS A 407 -27837-36924 13936 1005198 A ATOM 3346 CB LEU A 417 -27256-31317 11566 1009695 A ATOM 3264 CA LYS A 407 -27724-38368 14053 1004758 A ATOM 3347 CG LEU A 417 -28191 -30110 11561 1005506 A 65251/C766

ATOM 3348 CDl LEU A 417 -29305 -30329 12570 1005506 A ATOM 3433 OG SER A 428 -38959 -8432 4253 1009488 A

ATOM 3349 CD2LEUA417 -27413-28858 1188' 4 1005506 A ATOM 3434 C SER A 428 -38146-10433 2298 10013052 A

ATOM 3350 C LEUA417 -28679 -32092 9690 1006307 A ATOM 3435 O SER A 428 -37714 -9445 1702 10013040 A

ATOM 3351 O LEU A 417 -28239-31876 8552 1005817 A ATOM 3436 N SER A 429 37450-11562 2418 10014526 A

ATOM 3352 N THR A 418 -29956-31936 10020 1005585 A ATOM 3437 CA SER A 429 -36111-11689 1841 10014393 A

ATOM 3353 CA THR A 418 -30950 -31480 9060 1004891 A ATOM 3438 CB SER A 429 -35075-10983 2723 1007927 A

ATOM 3354 CB THR A 418 -31812-32638 8545 1008831 A ATOM 3439 OG SER A 429 35305 -9591 2786 1007927 A

ATOM 3355 OGl THRA418 -31029-3345C > 767: i 1005672 A ATOM 3440 C SER A 429 -35672-13132 1655 10014231 A

ATOM 3356 CG2 THR A 418 -33017-32117 ¹ 779C ) 1005672 A ATOM 3441 O SER A 429 -34645-13400 1035 10013101 A

ATOM 3357 C THR A 418 -31862-30482 9739 1006410 A ATOM 3442 N GLN A 430 -36452-14061 2186 1008004 A

ATOM 335S O THR A 418 -32590 -30855 10644 1005757 A ATOM 3443 CA GLN A 430 -36108-15474 2100 1008004 A

ATOM 3359 N ASP A 419 -31827-29222 9313 1006240 A ATOM 3444 CB GLN A 430 -35880-15917 0658 10018425 A

ATOM 3360 CA ASP A 419 -32677 -28207 9923 1006751 A ATOM 3445 CG GLN A 430 -35577-17397 0563 10011324 A

ATOM 3361 CB ASP A 419 -31828-27073 10494 10010278 A ATOM 3446 CD GLN A 430 -35303 -17852 -0847 10011324 A

ATOM 3362 CG ASP A 419 -32613-26192 11440 1008037 A ATOM 3447 OEl GLN A 430 -34276-17510 -1437 10011324 A

ATOM 3363 ODl ASP A 419 33290 26740 12332 1008037 A ATOM 3448 NE2GLNA430 -36225-18628 -1403 10011324 A

ATOM 3364 OD2ASPA419 -32559 -24956 11305 1008037 A ATOM 3449 C GLN A 430 -34832-15683 2894 1008004 A

ATOM 3365 C ASP A 419 -33677 -27656 8920 1007160 A ATOM 3450 O GLN A 430 -33762-15220 2502 1008004 A

ATOM 3366 O ASP A 419 -33297-27158 7863 1006649 A ATOM 3451 N PRO A 431 -34929-16403 4019 1006569 A

ATOM 3367 N LEU A 420 -34958 -27740 9262 1006303 A ATOM 3452 CD PRO A 431 -36045-17259 4457 1006890 A

ATOM 3368 CA LEU A 420 -36033-27281 8381 1006772 A ATOM 3453 CA PRO A 431 -33753-16642 4846 1006568 A

ATOM 3369 CB LEU A 420 -37122-28356 8317 10012420 A ATOM 3454 CB PRO A 431 -34316-17451 6006 10016786 A

ATOM 3370 CG LEU A 420 -38081-28334 7127 1008315 A ATOM 3455 CG PRO A 431 35347 18276 5335 10013842 A

ATOM 3371 CDl LEU A 420 -37295-28632 5857 ' 1008315 A ATOM 3456 C PRO A 431 -32631 -17372 4134 1006230 A

ATOM 3372 CD2 LEU A 420 -39182-29360 7325 i 1008315 A ATOM 3457 O PRO A 431 -32838-18058 3127 1006218 A

ATOM 3373 C LEU A 420 -36646 -25952 8834 1007029 A ATOM 3458 N VAL A 432 31438-17179 4678 1005606 A

ATOM 3374 O LEU A 420 -36613-25623 10015 1006961 A ATOM 3459 CA VAL A 432 -30227-17807 4206 1005844 A

ATOM 3375 N VAL A 421 -37211 -25194 7897 1007901 A ATOM 3460 CB VAL A 432 -29194-16754 3812 1008816 A

ATOM 3376 CA VAL A 421 -37820 -23906 8222 1007752 A ATOM 3461 CGl VAL A 432 -28845-15885 4997 1006024 A

ATOM 3377 CB VAL A 421 -36820 -22750 8020 10014204 A ATOM 3462 CG2VALA432 -27978 -17427 3287 1006024 A

ATOM 3378 CGl VAL A 421 -37510-21411 8210 1009747 A ATOM 3463 C VAL A 432 -29772-18599 5442 1005644 A

ATOM 3379 CG2 VAL A 421 -35700 -2288C ) 9008 1009747 A ATOM 3464 O VAL A 432 -30049-18207 6578 1004680 A

ATOM 3380 C VAL A 421 -39058-23618 7383 1007978 A ATOM 3465 N CYS A 433 -29105-19723 5241 1006422 A

ATOM 3381 O VAL A 421 -39064 -23824 6166 1007538 A ATOM 3466 CA CYS A 433 -28689-20523 6379 1006010 A

ATOM 3382 N ARG A 422 40100 23127 8046 1007554 A ATOM 3467 C CYS A 433 -27267-20205 6832 1005774 A

ATOM 3383 CA ARG A 422 -41365 -22795 7394 1007767 A ATOM 3468 O CYS A 433 -26324 -20287 6042 1005848 A

ATOM 3384 CB ARG A 422 -42487 -22809 8433 10018095 A ATOM 3469 CB CYS A 433 -28 SOO -22013 6032 10015366 A

ATOM 3385 CG ARG A 422 -43653 -23718 8107 10014154 A ATOM 3470 SG CYS A 433 -28469-23135 7429 10010077 A

ATOM 3386 CD ARG A 422 -44588 -23096 7093 10014154 A ATOM 3471 N VAL A 434 -27118-19826 8103 1004680 A

ATOM 3387 NE ARG A 422 -45780-23918 6908 10014154 A ATOM 3472 CA VAL A 434 -25800 -19544 8669 1004279 A

ATOM 3388 CZ ARG A 422 -46839 -23558 6190 10014154 A ATOM 3473 CB VAL A 434 -25765 -18233 9468 1005496 A

ATOM 3389 NHl ARG A 422 -46860 -22379 557' 9 10014154 A ATOM 3474 CGl VAL A 434 -24331 -17905 9827 1003674 A

ATOM 3390 NH2 ARG A 422 -47880-24374 6085 10014154 A ATOM 3475 CG2VALA434 -26375-17097 8653 1003674 A

ATOM 3391 C ARG A 422 -41273 -21409 6759 1007490 A ATOM 3476 C VAL A 434 -25457-20693 9613 1005319 A

ATOM 3392 O ARG A 422 -41396-20402 7451 1006557 A ATOM 3477 O VAL A 434 26154 20921 10600 1004425 A

ATOM 3393 N THR A 423 -41065 -21359 5446 10011319 A ATOM 3478 N VAL A 435 -24382-21409 9298 1004099 A

ATOM 3394 CA THR A 423 -40949 -20084 4739 10012284 A ATOM 3479 CA VAL A 435 -23939-22558 10082 1003273 A

ATOM 3395 CB THR A 423 -40407 -20277 3294 10020084 A ATOM 3480 CB VAL A 435 -23565-23710 9146 1005812 A

ATOM 3396 OGl THR A 423 -39152-2096( i 3337 10016451 A ATOM 3481 CGl VAL A 435 -22868 -24809 9909 1003745 A

ATOM 3397 CG2 THR A 423 -40197-18926 i 260S > 10016451 A ATOM 3482 CG2VALA435 -24816-24229 8465 1003745 A

ATOM 3398 C THR A 423 -42282-19351 4648 10012106 A ATOM 3483 C VAL A 435 -22753 -22279 10985 1004065 A

ATOM 3399 O THR A 423 -42799-19146 3555 10011955 A ATOM 3484 O VAL A 435 -21691 -21882 10506 1004124 A

ATOM 3400 N THR A 424 -42841 -18958 5790 10016652 A ATOM 3485 N PHE A 436 -22937-22497 12289 1004037 A

ATOM 3401 CA THR A 424 -44109-18237 5790 10016652 A ATOM 3486 CA PHE A 436 -21868-22282 13259 1003657 A

ATOM 3402 CB THR A 424 -44612-17976 7221 10018067 A ATOM 3487 CB PHE A 436 -22389 -21531 14469 1006477 A

ATOM 3403 OGl THR A 424 -44737-1922; i 791; J 10012648 A ATOM 3488 CG PHE A 436 -22863 -20154 14159 1003954 A

ATOM 3404 CG2 THR A 424 45971 17275 ' 719' 1 10012648 A ATOM 3489 CDl PHE A 436 -24172-19929 13764 1003954 A

ATOM 3405 C THR A 424 -43913-16905 5075 10016652 A ATOM 3490 CD2PHEA436 -21996-19065 14268 1003954 A

ATOM 3406 O THR A 424 -42797-16388 5008 10016652 A ATOM 3491 CEl PHE A 436 -24618-18638 13483 1003954 A

ATOM 3407 N SER A 425 -44996-16350 4544 10013915 A ATOM 3492 CE2PHEA436 -22433-17760 13987 1003954 A

ATOM 3408 CA SER A 425 -44922-15091 3815 10013915 A ATOM 3493 CZ PHE A 436 -23746-17548 13595 1003954 A

ATOM 3409 CB SER A 425 -46191 -14892 2989 10018353 A ATOM 3494 C PHE A 436 -21279 -23608 13698 1004440 A

ATOM 3410 OG SER A 425 -46081-13732 2181 1007947 A ATOM 3495 O PHE A 436 -21970-24448 14259 1004378 A

ATOM 3411 C SER A 425 -44698 -13870 4701 10013915 A ATOM 3496 N HIS A 437 -19994 23791 13430 1003897 A

ATOM 3412 O SER A 425 -44599-12749 4204 10013915 A ATOM 3497 CA HIS A 437 -19295-25015 13797 1004004 A

ATOM 3413 N LYS A 426 -44617-14086 6010 10016946 A ATOM 3498 CB HIS A 437 -19457-26040 12688 1006620 A

ATOM 3414 CA LYS A 426 -44403-12991 6953 10016946 A ATOM 3499 CG HIS A 437 18805-27345 12983 1004257 A

ATOM 3415 CB LYS A 426 -44306-13536 8377 10018402 A ATOM 3500 CD2 HIS A 437 -17609-27847 12604 1004257 A

ATOM 3416 CG LYS A 426 _45448 -14443 8779 10012832 A ATOM 3501 NDl HIS A 437 -19376-28291 13800 1004257 A

ATOM 3417 CD LYS A 426 -45174-15072 10128 ; 10012832 A ATOM 3502 CEl HIS A 437 -18560-29321 13914 1004257 A

ATOM 3418 CE LYS A 426 -46235-16092 10485 10012832 A ATOM 3503 NE2 HIS A 437 -17480-29078 13198 1004257 A

ATOM 3419 NZ LYS A 426 -45936-16742 11790 10012832 A ATOM 3504 C HIS A 437 -17807-24722 14024 1004435 A

ATOM 3420 C LYS A 426 -43121 12225 6632 10016946 A ATOM 3505 O HIS A 437 -17302-23702 13563 1004657 A

ATOM 3421 O LYS A 426 -43075-10998 6735 10016946 A ATOM 3506 N ASP A 438 -17107-25603 14733 1004989 A

ATOM 3422 N MET A 427 -42082 -12963 6247 10017116 A ATOM 3507 CA ASP A 438 -15686-25393 15008 1005180 A

ATOM 3423 CA MET A 427 -40785-12380 5921 10017116 A ATOM 3508 CB ASP A 438 -15130-26561 15820 1009938 A

ATOM 3424 CB MET A 427 -39751 -13488 5725 10016817 A ATOM 3509 CG ASP A 438 -15370-26393 17314 1007034 A

ATOM 3425 CG MET A 427 -40177-14559 4743 10016817 A ATOM 3510 ODl ASP A 438 -16297-25632 17681 1007034 A

ATOM 3426 SD MET A 427 -38937-15846 4601 10016817 A ATOM 3511 OD2ASPA438 -14635-27026 18113 1007034 A

ATOM 3427 CE MET A 427 -39258-16799 6088 10016817 A ATOM 3512 C ASPA438 -14886-25178 13731 1005314 A

ATOM 3428 C MET A 427 -40816-11491 4686 10017116 A ATOM 3513 O ASP A 438 -14058-24273 13652 1005670 A

ATOM 3429 O MET A 427 -41879-11043 4257 10017116 A ATOM 3514 N THR A 439 -15121-26016 12733 1006828 A

ATOM 3430 N SER A 428 -39640-11240 4117 10013292 A ATOM 3515 CA THRA439 -14460-25849 11448 1006563 A

ATOM 3431 CA SER A 428 -39533-10395 2935 10013457 A ATOM 3516 CB THR A 439 -14530-27152 10627 1004593 A

ATOM 3432 CB SER A 428 -39875 -8947 3299 1009817 A ATOM 3517 OGl THR A 439 -15892-27475 10324 1003174 A 65251/C766

ATOM 3518 CG2THRA439 -13928-28304 11436 1003174 A ATOM 3603 N CYS A 451 -32272-25221 -5133 10019868 A ATOM 3519 C THR A 439 -15350-24770 10846 1007140 A ATOM 3604 CA CYS A 451 -30934-24791 -5497 10019868 A ATOM 3520 O THR A 439 -16542-24765 11116 1007174 A ATOM 3605 CB CYS A 451 -29900-25348 -4550 10013657 A ATOM 3521 N LEU A 440 -14805-23858 10052 1005891 A ATOM 3606 SG CYS A 451 -30053 -24597 -2924 10013657 A ATOM 3522 CA LEU A 440 -15608-22751 9498 1006093 A ATOM 3607 C CYS A 451 -30650 -25309 -6856 10019868 A ATOM 3523 CB LEU A 440 -16609-23236 8412 1008218 A ATOM 3608 O CYS A 451 -29637 -26042 -6985 10019868 A ATOM 3524 CG LEU A 440 -17824-24212 8366 1006218 A ATOM 3609 OXT CYS A 451 -31454-24969 -7751 10010894 ATOM 3525 CDl LEU A 440 -17339-25622 8529 1006218 A A ATOM 3526 CD2LEUA440 -18898 23887 9379 1006218 A ATOM 3610 CB ARGB -12181 20412 42960 10014465 B ATOM 3527 C LEU A 440 -16365-21970 10576 1007088 A ATOM 3611 CG ARGB -11 150 19470 43601 10014465 B ATOM 3528 O LEU A 440 -17567-22124 10711 1006910 A ATOM 3612 CD ARGB -11061 19589 45123 10014465 B ATOM 3529 N GLU A 441 -15660-21127 11334 1006807 A ATOM 3613 NE ARGB 11936 18648 45827 10014465 B ATOM 3530 CA GLU A 441 -16267-20330 12414 1006807 A ATOM 3614 CZ ARG B -11808 17321 45795 10014465 B ATOM 3531 CB GLU A 441 -15457-19051 12643 10019778 A ATOM 3615 NHlARGB 1 -10838 16754 45091 10014465 B ATOM 3532 CG GLU A 441 -14041 -19303 13148 10012114 A ATOM 3616 NH2ARGB 1 -12656 16556 46468 10014465 B ATOM 3533 CD GLU A 441 -13312-18018 13522 10012114 A ATOM 3617 C ARG B 1 -14068 18754 43190 10019714 B ATOM 3534 OEl GLU A 441 -13175-17129 12651 10012114 A ATOM 3618 O ARGB 1 -13658 17869 43940 10019714 B ATOM 3535 OE2GLUA441 -12875-17898 14689 10012114 A ATOM 3619 N ARG B 1 -13815 20630 44809 10019714 B ATOM 3536 C GLU A 441 -17750-19984 12201 1006807 A ATOM 3620 CA ARG B 1 13643 20212 43390 10019714 B ATOM 3537 O GLU A 441 -18567-20106 13112 1006807 A ATOM 3621 N THRB 2 -14898 18510 42180 10019964 B ATOM 3538 N ALA A 442 -18097-19555 10997 1006816 A ATOM 3622 CA THRB 2 -15383 17161 41889 10019964 B ATOM 3539 CA ALA A 442 -19484-19237 10682 1006638 A ATOM 3623 CB THR B 2 16639 17199 40977 10012184 B ATOM 3540 CB ALA A 442 -19948-18044 11482 1003577 A ATOM 3624 OGlTHRB 2 -17657 18006 41582 10012058 B ATOM 3541 C ALA A 442 -19624-18955 9193 1006237 A ATOM 3625 CG2THRB 2 -17179 15786 40747 10012373 B ATOM 3542 O ALA A 442 -19168-17920 8707 1005978 A ATOM 3626 C THRB 2 -14327 16327 41 170 10019964 B ATOM 3543 N GLN A 443 -20244 -19885 S 465 I 003404 A ATOM 3627 O THRB 2 -14014 16604 40011 10019964 B ATOM 3544 CA GLN A 443 -20446-19730 7025 1003732 A ATOM 3628 N PRO B 3 -13750 15306 41 841 10020084 B ATOM 3545 CB GLN A 443 19868-20907 6268 1007657 A ATOM 3629 CD PRO B 3 -13820 14857 43246 1008010 B ATOM 3546 CG GLN A 443 -18440-20707 5866 1005980 A ATOM 3630 CA PROB 3 -12753 14533 41096 10020084 B ATOM 3547 CD GLN A 443 -18043-21629 4730 1005980 A ATOM 3631 CB PROB 3 -12528 13310 41989 1007834 B ATOM 3548 OEl GLN A 443 -18742-21709 3709 1005980 A ATOM 3632 CG PROB 3 -12606 13914 43362 1007821 B ATOM 3549 NE2GLNA443 -16917-22331 4891 1005980 A ATOM 3633 C PROB 3 -13337 14197 39720 10020084 B ATOM 3550 C GLN A 443 -21906-19562 6625 1003949 A ATOM 3634 O PRO B 3 -12612 14165 38723 10020084 B ATOM 3551 O GLN A 443 -22807-20112 7260 1004055 A ATOM 3635 N SERB 4 -14655 13977 39682 10013514 B ATOM 3552 N VAL A 444 -22134-18791 5563 1005318 A ATOM 3636 CA SERB 4 -15386 13689 38444 10013171 B ATOM 3553 CA VAL A 444 -23486-18546 5082 1005033 A ATOM 3637 CB SERB 4 -14551 12832 37483 10015837 B ATOM 3554 CB VAL A 444 -23680-17067 4729 1006780 A ATOM 3638 OG SERB 4 -14634 11457 37815 10016032 B ATOM 3555 CGl VAL A 444 -25156-16753 4625 1006010 A ATOM 3639 C SERB 4 16727 12994 38649 10013205 B ATOM 3556 CG2VALA444 -23024-16192 5782 1006010 A ATOM 3640 O SERB 4 -17650 13211 37865 10013220 B ATOM 3557 C VAL A 444 -23760-19411 3853 1005415 A ATOM 3641 N ASPB 5 -16822 12169 39695 1005917 B ATOM 3558 O VAL A 444 -22875-19623 3018 1005641 A ATOM 3642 CA ASP B 5 18032 11390 40012 1005928 B ATOM 3559 N TYR A 445 -24979-19940 3763 1004477 A ATOM 3643 CB ASP B 5 -19232 11931 39216 10014025 B ATOM 3560 CA TYR A 445 -25375 -20798 2642 1004384 A ATOM 3644 CG ASP B 5 -20499 11 140 39439 10014025 B ATOM 3561 CB TYR A 445 -25375 -22261 3068 1007899 A ATOM 3645 ODl ASP B 5 21484 11386 38707 10014025 B ATOM 3562 CG TYR A 445 -24033 -22737 3562 1005141 A ATOM 3646 OD2ASPB 5 -20519 10280 40342 10013881 B ATOM 3563 CDl TYR A 445 -23690 -22654 4915 1005141 A ATOM 3647 C ASP B 5 -177S2 9904 39663 1005678 B ATOM 3564 CEl TYR A 445 -22437-23100 5380 1005141 A ATOM 3648 O ASPB 5 -18417 9005 40206 1006029 B ATOM 3565 CD2TYRA445 -23095 23269 2680 1005141 A ATOM 3649 N LYSB 6 -16833 9662 38762 1005552 B ATOM 3566 CE2TYRA445 -21845 -23711 3128 1005141 A ATOM 3650 CA LYS B -16483 8314 38312 1005190 B ATOM 3567 CZ TYR A 445 21526 23627 4479 1005141 A ATOM 3651 CB LYS B -15607 8372 37053 1004808 B ATOM 3568 OH TYR A 445 -20316-24095 4924 1005141 A ATOM 3652 CG LYS B -16228 8822 35760 1005449 B ATOM 3569 C TYR A 445 -26753-20400 2131 1004530 A ATOM 3653 CD LYS B -15123 8942 34711 1005810 B ATOM 3570 O TYR A 445 27671 -20145 2913 1004816 A ATOM 3654 CE LYS B -15679 9163 33325 1006137 B ATOM 3571 N THR A 446 -26907-20378 0811 1003937 A ATOM 3655 NZ LYS B -16498 7986 32898 1006256 B ATOM 3572 CA THR A 446 -28167-19931 0219 1004635 A ATOM 3656 C LYS B 6 -15663 7554 39331 1004723 B ATOM 3573 CB THR A 446 -27921 -18690 -0660 1006548 A ATOM 3657 O LYS B 6 -14705 8102 39873 10051 11 B ATOM 3574 OGl THR A 446 -26950-19015 -1661 1005363 A ATOM 3658 N PRO B 7 -16015 6290 39613 1003762 B ATOM 3575 CG2THRA446 -27402-17530 0167 1005363 A ATOM 3659 CD PRO B 7 -17210 5510 39293 1002909 B ATOM 3576 C THR A 446 -28962-20913 -0626 1005615 A ATOM 3660 CA PRO B 7 -15188 5567 40580 1003566 B ATOM 3577 O THR A 446 -28851 -22129 -0488 1005982 A ATOM 3661 CB PRO B 7 -15873 4203 40694 1003109 B ATOM 3578 N CYS A 447 -29771 -20310 -1497 1008335 A ATOM 3662 CG PRO B 7 -16687 4102 39479 1002996 B ATOM 3579 CA CYS A 447 -30663 -20928 -2490 1008433 A ATOM 3663 C PROB 7 -13793 5473 39964 1003372 B ATOM 3580 C CYS A 447 -31835 -21800 -2062 1008436 A ATOM 3664 O PROB 7 13652 5165 38774 1003473 B ATOM 3581 O CYS A 447 -31756-22585 -1126 1008122 A ATOM 3665 N VALB 8 -12771 5768 40765 1002672 B ATOM 3582 CB CYS A 447 -29854-21658 -3576 10012613 A ATOM 3666 CA VAL B 8 -11402 5748 40280 1002788 B ATOM 3583 SG CYS A 447 -28797-23014 -3007 10011166 A ATOM 3667 CB VAL B 8 -11050 7107 39625 1002559 B ATOM 3584 N SER A 448 -32939 -21617 -2785 10020084 A ATOM 3668 CGl VALB 8 -11258 8232 40622 1002617 B ATOM 3585 CA SER A 448 -34181 -22343 -2559 10020084 A ATOM 3669 CG2 VAL B 8 -9614 7108 39126 1002829 B ATOM 3586 CB SER A 448 -35265 21393 2049 10020084 A ATOM 3670 C VALB 8 -10424 5478 41416 1003038 B ATOM 3587 OG SER A 448 -34863 -20775 -0840 10020084 A ATOM 3671 O VALB 8 -10738 5660 42598 1002962 B ATOM 3588 C SER A 448 -34632 -22990 -3867 10020084 A ATOM 3672 N ALAB 9 -9227 5043 41059 1002974 B ATOM 3589 O SER A 448 -33805 -23252 -4742 10020084 A ATOM 3673 CA ALA B 9 -8221 4799 42062 1003598 B ATOM 3590 N GLU A 449 -35939-23221 -4009 1009688 A ATOM 3674 CB ALA B 9 -8564 3573 42847 1002993 B ATOM 3591 CA GLU A 449 -36475 -23880 -5202 1009688 A ATOM 3675 C ALAB 9 -6866 4627 41420 1003696 B ATOM 3592 CB GLU A 449 -35970 -23198 -6482 10012121 A ATOM 3676 O ALAB 9 -6732 3983 40377 1003494 B ATOM 3593 CG GLU A 449 -36712-21927 -6856 10012121 A ATOM 3677 N HIS B 10 -5866 5238 42035 1003363 B ATOM 3594 CD GLU A 449 -36910 -21000 -5673 10012121 A ATOM 3678 CA HISB 10 -4497 5117 41580 1003450 B ATOM 3595 OEl GLU A 449 -35908-20645 -5019 10012121 A ATOM 3679 CB HISB 10 -4050 6361 40817 1003060 B ATOM 3596 OE2GLUA449 -38069-20626 -5398 10012121 A ATOM 3680 CG HISB 10 2651 6266 40293 1003209 B ATOM 3597 C GLU A 449 -35976 -25320 -5160 1009688 A ATOM 3681 CD2HISB 10 -1481 6727 40793 1002982 B ATOM 3598 O GLU A 449 -36711 -26259 -5432 1009688 A ATOM 3682 NDl HIS B 10 -2328 5564 39153 1003223 B ATOM 3599 N GLY A 450 -34711 -25467 -4789 1006163 A ATOM 3683 CEl HISB 10 -1021 5592 38973 1003258 B ATOM 3600 CA GLY A 450 -34063 -26756 -4695 1006163 A ATOM 3684 NE2HISB 10 -0484 6291 39956 1003006 B ATOM 3601 C GLY A 450 -32618-26504 -5060 1006163 A ATOM 3685 C HISB 10 -3709 4991 42872 1003271 ATOM 3602 O GLY A 450 31843 27436 5266 1006163 A ATOM 3686 O HIS B 10 -3425 5994 43543 1003087 65251/C766

ATOM 3687 N VAL B 11 -3 397 3 760 43 250 1 00 39 61 B ATOM 3772 C GLN B 22 1 104 -1627 49331 1006129 B ATOM 3688 CA VAL B 11 -2 652 3 531 44478 1 0042 19 B ATOM 3773 O GLN B 22 1878 -0691 49235 1006024 B ATOM 3689 CB VALB 11 -3 237 2356 45285 1 0032 32 B ATOM 3774 N TRP B 23 -0141 -1569 48876 1004096 B ATOM 3690 CGl VAL B 11 -4 664 2 693 45 669 1 00 28 38 B ATOM 3775 CA TRP B 23 -0669 -0377 48205 1003484 B ATOM 3691 CG2 VAL B 11 -3 204 1 062 44 474 1 00 3430 B ATOM 3776 CB TRP B 23 -1766 -0761 47207 1003227 B ATOM 3692 C VAL B 11 1 205 3 275 44 149 1 0040 80 B ATOM 3777 CG TRP B 23 -1375 -1775 46196 1003279 B ATOM 3693 O VAL B 11 -0 872 2 824 43 055 1 00 3781 B ATOM 3778 CD2 TRP B 23 -0444 -1606 45114 1003090 B ATOM 3694 N VAL B 12 -0 339 3 568 45 100 1 004454 B ATOM 3779 CE2 TRP B 23 -0384 -2836 44420 1003252 B ATOM 3695 CA VAL B 12 1 078 3 408 44 874 1 0042 71 B ATOM 3780 CE3 TRP B 23 0347 -0537 44666 1003059 B ATOM 3696 CB VAL B 12 1 718 4790 44 850 1 00 46 95 B ATOM 3781 CDl TRP B 23 -1828 -3049 46116 1003226 B ATOM 3697 CGl VAL B 12 1 764 5 358 46 258 1 0040 75 B ATOM 3782 NEl TRP B 23 -1240 -3696 45051 1003135 B ATOM 3698 CG2 VAL B 12 3 084 4 717 44 221 1 00 5042 B ATOM 3783 CZ2 TRP B 23 0436 -3030 43301 1003458 B ATOM 3699 C VAL B 12 1 692 2 532 45962 1 004067 B ATOM 3784 CZ3 TRP B 23 1 160 -0730 43553 1003503 B ATOM 3700 O VAL B 12 1 097 2 365 47 034 1 0040 51 B ATOM 3785 CH2 TRP B 23 1 196 -1970 42886 1003284 B ATOM 3701 N ALA B 13 2 873 1 979 45 693 1 0056 19 B ATOM 3786 C TRP B 23 -1262 0663 49138 1003534 B ATOM 3702 CA ALA B 13 3 550 1 097 46 656 1 00 55 86 B ATOM 3787 O TRP B 23 -1986 0323 50074 1003662 B ATOM 3703 CB ALA B 13 4 666 0319 45 971 1 00 19 80 B ATOM 3788 N LEU B 24 -0962 1933 48881 1003924 B ATOM 3704 C ALA B 13 4 119 1 812 47 862 1 0059 84 B ATOM 3789 CA LEU B 24 -1 529 3013 49692 1003693 B ATOM 3705 O ALA B 13 4676 2 897 47 736 1 005735 B ATOM 3790 CB LEU B 24 -0507 3685 50625 1004814 B ATOM 3706 N ASN B 14 3 988 1 185 49 028 1 004954 B ATOM 3791 CG LEU B 24 0827 3044 50956 1004887 B ATOM 3707 CA ASN B 14 4 494 I 737 50284 1 00 50 66 B ATOM 3792 CDl LEU B 24 1704 3142 49726 1005049 B ATOM 3708 CB ASN B 14 3 733 1 132 51 455 1 00 57 90 B ATOM 3793 CD2 LEU B 24 1476 3762 52110 1004398 B ATOM 3709 CG ASN B 14 4 210 1 653 52 793 1 00 59 89 B ATOM 3794 C LEU B 24 -2098 4075 48783 1004379 B ATOM 3710 ODl ASN B 14 3 745 1 205 53 843 1 005947 B ATOM 3795 O LEU B 24 -1725 4185 47613 1004077 B ATOM 3711 ND2 ASN B 14 5 140 2 606 52 766 1 00 6201 B ATOM 3796 N ASN B 25 -3005 4860 49342 1003494 B ATOM 3712 C ASN B 14 5 974 1 399 50412 1 00 53 54 B ATOM 3797 CA ASN B 25 -3642 5929 48605 1003638 B ATOM 3713 O ASN B 14 6335 0 226 50 504 1 005406 B ATOM 3798 CB ASN B 25 -5 134 5668 48514 1004312 B ATOM 3714 N PRO B 15 6 852 2 419 50434 1 00 62 22 B ATOM 3799 CG ASN B 25 -5823 5907 49827 1004469 B ATOM 3715 CD PRO B 15 6 601 3 863 50 316 1 00 38 30 B ATOM 3800 ODl ASN B 25 -6623 6829 49958 1004868 B ATOM 3716 CA PRO B 15 8 291 2 150 50 543 1 00 65 82 B ATOM 3801 ND2 ASN B 25 -5499 5088 50823 1004109 B ATOM 3717 CB PRO B 15 8 936 3 470 50 098 1 00 42 64 B ATOM 3802 C ASN B 25 -3419 7257 49321 1003691 B ATOM 3718 CG PRO B 15 7 794 4292 49 515 1 00 40 91 B ATOM 3803 O ASN B 25 -3834 8302 48835 1003927 B ATOM 3719 C PRO B 15 8709 1 757 51 956 1 00 67 03 B ATOM 3804 N ARG B 26 -2769 7214 50476 1004206 B ATOM 3720 O PRO B 15 9766 1 158 52 160 1 0069 06 B ATOM 3805 CA ARG B 26 -2520 8428 51247 1004334 B ATOM 3721 N GLN B 16 7 866 2 095 52 925 1 00 89 15 B ATOM 3806 CB ARG B 26 -2493 8092 52744 1004875 B ATOM 3722 CA GLN B 16 8 141 1 802 54 327 1 00 88 10 B ATOM 3807 CG ARG B 26 -1480 7026 53138 1004966 B ATOM 3723 CB GLN B 16 7 324 2 750 55 214 1 00104 52 B ATOM 3808 CD ARG B 26 -1 310 6985 54646 1005372 B ATOM 3724 CG GLN B 16 7 832 2 914 56 641 1 0010745 B ATOM 3809 NE ARG B 26 0358 5961 55060 1005486 B ATOM 3725 CD GLN B 16 9 253 3 451 56703 1 0010924 B ATOM 3810 CZ ARG B 26 -0661 4678 55206 I 005542 B ATOM 3726 OEl GLN B 16 9 610 4380 55 975 1 00111 36 B ATOM 3811 NHl ARG B 26 -1896 4257 54976 1005590 B ATOM 3727 NE2 GLN B 16 10 068 2 875 57 584 1 00107 89 B ATOM 3812 NH2 ARG B 26 0269 3817 55582 1005445 B ATOM 3728 C GLN B 16 7 829 0 345 54 682 1 00 84 77 B ATOM 3813 C ARG B 26 -1230 9176 50870 1004140 B ATOM 3729 O GLN B 16 7958 -0 060 55 840 1 0085 34 B ATOM 3814 O ARG B 26 -0459 9584 51740 10041 11 B ATOM 3730 N ALA B 17 7422 -0444 53 688 1 00 7670 B ATOM 3815 N ARG B 27 -1000 9365 49575 1004077 B ATOM 3731 CA ALA B 17 7 104 -1 852 53 923 1 00 8046 B ATOM 3816 CA ARG B 27 0196 10052 49126 10041 70 B ATOM 3732 CB ALA B 17 5 651 -2 131 53 568 1 00 40 98 B ATOM 3817 CB ARG B 27 1206 9051 48577 1003501 B ATOM 3733 C ALA B 17 8 024 2 759 53 117 1 008496 B ATOM 3818 CG ARG B 27 1770 8148 49631 1003643 B ATOM 3734 O ALA B 17 7 580 -3 497 52243 1 00 86 60 B ATOM 3819 CD ARG B 27 2301 8960 50798 1003880 B ATOM 3735 N GLU B 18 9314 -2 699 53 429 1 009479 B ATOM 3820 NE ARG B 27 2756 8138 51911 1004219 B ATOM 3736 CA GLU B 18 10318 -3 501 52 744 1 009679 B ATOM 3821 CZ ARG B 27 3764 7276 51834 1004580 B ATOM 3737 CB GLU B IS 11 662 -3 387 53 466 1 0098 21 B ATOM 3822 NHl ARG B 27 4101 6574 52910 1004667 B ATOM 3738 CG GLU B 18 11 630 -3 885 54902 1 009821 B ATOM 3823 NH2 ARG B 27 4433 7116 50685 1004403 B ATOM 3739 CD GLU B 18 13 000 -3 885 55 545 1 009821 B ATOM 3824 C ARG B 27 -0050 11 136 48097 1004216 B ATOM 3740 OEl GLU B 18 13 893 -4 591 55 028 1 00 9821 B ATOM 3825 O ARG B 27 -1 170 11337 47625 1004230 B ATOM 3741 0E2 GLU B 18 13 187 -3 183 56 562 1 009821 B ATOM 3826 N ALA B 28 1036 11820 47766 1007646 B ATOM 3742 C GLU B 18 9 930 -4 971 52 648 1 00 9645 B ATOM 3827 CA ALA B 28 1061 12915 46816 1007536 B ATOM 3743 O GLU B 18 9246 -5 509 53 523 1 009606 B ATOM 3828 CB ALA B 28 2443 13012 46197 10012557 B ATOM 3744 N GLY B 19 10 373 -5 606 51 569 1 00 77 61 B ATOM 3829 C ALA B 28 0021 12873 45720 1007502 B ATOM 3745 CA GLY B 19 10099 -7 015 51 366 1 0075 10 B ATOM 3830 O ALA B 28 -1050 13461 45845 1007604 B ATOM 3746 C GLY B 19 8 719 -7 384 50862 1 0073 60 B ATOM 3831 N ASN B 29 0328 12185 44633 1005689 B ATOM 3747 O GLY B 19 8480 -8 542 50517 1 00 73 61 B ATOM 3832 CA ASN B 29 -0614 12144 43521 1005606 B ATOM 3748 N GLN B 20 7 804 -6 423 50 807 1 00101 28 B ATOM 3833 CB ASN B 29 0113 12535 42234 1004041 B ATOM 3749 CA GLN B 20 6456 -6 714 50 336 1 00 96 85 B ATOM 3834 CG ASN B 29 0643 13958 42281 1004047 B ATOM 3750 CB GLN B 20 5 543 -6970 51 530 1 00103 39 B ATOM 3835 ODl ASN B 29 -0091 14913 42035 1004633 B ATOM 3751 CG GLN B 20 5 577 -5 857 52 551 1 00104 37 B ATOM 3836 ND2 ASN B 29 1920 14105 42625 1003748 B ATOM 3752 CD GLN B 20 4 728 6 157 53 762 1 00104 13 B ATOM 3837 C ASN B 29 -1284 10793 43364 1005440 B ATOM 3753 OEl GLN B 20 4 952 -7 148 54456 1 00103 78 B ATOM 3838 O ASN B 29 -1 163 10148 42324 1005212 B ATOM 3754 NE2 GLN B 20 3 743 -5 301 54 025 1 00103 58 B ATOM 3839 N ALA B 30 -1993 10369 44405 1004666 B ATOM 3755 C GLN B 20 5 878 5 600 49468 1 0091 59 B ATOM 3840 CA ALA B 30 -2683 9089 44393 1004148 B ATOM 3756 O GLN B 20 6448 -4 514 49 364 1 009030 B ATOM 3841 CB ALA B 30 -2212 8249 45552 1003313 B ATOM 3757 N LEU B 21 4 742 -5 879 48 839 1 0060 98 B ATOM 3842 C ALA B 30 -4190 9321 44475 1004288 B ATOM 3758 CA LEU B 21 4 090 -4902 47 981 1 00 5744 B ATOM 3843 O ALA B 30 -4642 10440 44746 1004703 B ATOM 3759 CB LEU B 21 3 877 -5 482 46 582 1 00 4774 B ATOM 3844 N LEU B 31 -4966 8270 44238 1004200 B ATOM 3760 CG LEU B 21 3 138 -4 621 45 550 1 00 46 52 B ATOM 3845 CA LEU B 31 -6416 8395 44269 1004147 B ATOM 3761 CDl LEU B 21 3 722 -3 215 45 520 1 0043 82 B ATOM 3846 CB LEU B 31 -6952 8668 42873 1003485 B ATOM 3762 CD2 LEU B 21 3 247 -5282 44 180 1 0048 56 B ATOM 3847 CG LEU B 31 6745 10003 42201 1003773 B ATOM 3763 C LEU B 21 2 755 -4 501 48 575 1 00 56 05 B ATOM 3848 CDl LEU B 31 -7047 9870 40716 1003535 B ATOM 3764 O LEU B 21 1 742 -5 149 48 339 1 00 51 37 B ATOM 3849 CD2 LEU B 31 -7645 11021 42853 1003720 B ATOM 3765 N GLN B 22 2 759 -3 424 49 349 1 0059 30 B ATOM 3850 C LEU B 31 -7128 7153 44784 1004073 B ATOM 3766 CA GLN B 22 1 545 -2 935 49 993 1 00 63 90 B ATOM 3851 O LEU B 31 -6665 6023 44604 1004154 B ATOM 3767 CB GLN B 22 1 834 -2 728 51 480 1 00 55 04 B ATOM 3852 N LEU B 32 -8277 7387 45409 1003938 B ATOM 3768 CG GLN B 22 0 737 -2 058 52 266 1 00 61 81 B ATOM 3853 CA LEU B 32 -9143 6334 45931 1003917 B ATOM 3769 CD GLN B 22 1 212 -1 604 53 637 1 00 68 03 B ATOM 3854 CB LEU B 32 -8588 5758 47228 1002567 B ATOM 3770 OEl GLN B 22 0 489 -0927 54371 1 00 73 26 B ATOM 3855 CG LEU B 32 -9438 4575 47717 1002425 B ATOM 3771 NE2 GLN B 22 2 438 1 977 53 986 1 00 68 79 B ATOM 3856 CDl LEU B 32 -9355 3402 46721 1002323 B 65251/C766

ATOM 3857 CD2 LEU B 32 -8963 4157 49110 1002457 ATOM 3942 CD2 LEU B 43 -7635 -0028 44762 1002545 B ATOM 3858 C LEU B 32 -10472 7030 46194 1003881 ATOM 3943 C LEU B 43 -10600 -3286 44792 1003941 B ATOM 3859 O LEU B 32 -10762 7428 47318 1004468 ATOM 3944 O LEU B 43 10699 -4353 44221 1003603 B ATOM 3860 N ALA B 33 -11280 7173 45150 1003973 ATOM 3945 N VAL B 44 -11644 -2660 45307 1003405 B ATOM 3861 CA ALA B 33 -12534 7888 45291 1004025 B ATOM 3946 CA VAL B 44 -12970 -3245 45196 1003373 B ATOM 3862 CB ALA B 33 -12350 9313 44808 1004067 B ATOM 3947 CB VAL B 44 -13580 -3538 46581 I 002724 B ATOM 3863 C ALA B 33 -13764 7311 44629 1004204 B ATOM 3948 CGl VAL B 44 -14868 -4298 46405 1002843 B ATOM 3864 O ALA B 33 -13711 6344 43873 1004622 B ATOM 3949 CG2 VAL B 44 -12593 -4335 47432 10021 85 B ATOM 3865 N ASN B 34 -14879 7965 44931 1004237 B ATOM 3950 C VAL B 44 -13907 -2332 44435 1003274 B ATOM 3866 CA ASN B 34 -16184 7625 44404 1003956 B ATOM 3951 O VAL B 44 -14174 -1 199 44854 1003378 B ATOM 3867 CB ASN B 34 -16256 8047 42951 1004230 B ATOM 3952 N VAL B 45 -14404 -2839 43314 1002940 B ATOM 3868 CG ASN B 34 -16033 9514 42788 1004622 B ATOM 3953 CA VAL B 45 -15306 -2095 42446 1003514 B ATOM 3869 ODl ASN B 34 -16670 10316 43464 1004870 B ATOM 3954 CB VAL B 45 -15444 -2828 41 113 1004166 B ATOM 3870 ND2 ASN B 34 15126 9886 41899 1004163 B ATOM 3955 CGl VAL B 45 -16582 -2246 40311 1004423 B ATOM 3871 C ASN B 34 -16621 6187 44548 1004031 B ATOM 3956 CG2 VAL B 45 -14143 -2714 40350 1004506 B ATOM 3872 O ASN B 34 -17198 5620 43635 1004285 B ATOM 3957 C VAL B 45 -16689 1862 43077 1003693 B ATOM 3873 N GLY B 35 -16345 5591 45693 1004299 B ATOM 3958 O VAL B 45 -17315 -2775 43595 1003638 B ATOM 3874 CA GLY B 35 -16794 4241 45892 1003758 B ATOM 3959 N PRO B 46 -17182 -0624 43029 1004190 B ATOM 3875 C GLY B 35 -15779 3130 45911 1003793 B ATOM 3960 CD PRO B 46 16435 0594 42659 1004912 B ATOM 3876 O GLY B 35 -15967 2168 46652 1003942 B ATOM 3961 CA PRO B 46 -18485 -0285 43609 1004075 B ATOM 3877 N VAL B 36 -14718 3202 45120 1003594 B ATOM 3962 CB PRO B 46 -18274 1 148 44072 1004848 B ATOM 3878 CA VAL B 36 -13791 2084 45167 1003727 B ATOM 3963 CG PRO B 46 17450 1707 42938 1004918 B ATOM 3879 CB VAL B 36 -12804 2088 43950 1003776 B ATOM 3964 C PRO B 46 -19703 -0392 42693 1004419 B ATOM 3880 CGl VAL B 36 -12938 3368 43193 1003579 B ATOM 3965 O PRO B 46 -20825 0194 43146 1004665 B ATOM 3881 CG2 VAL B 36 -11379 1836 44395 1003816 B ATOM 3966 N SER B 47 -19499 -0683 41412 1006481 B ATOM 3882 C VAL B 36 -13085 2062 46513 1004142 B ATOM 3967 CA SER B 47 -20635 -0768 40499 1006193 B ATOM 3883 O VAL B 36 -12752 3101 47076 1004238 B ATOM 3968 CB SER B 47 -21 141 0639 40193 1005846 B ATOM 3884 N GLU B 37 -12909 0862 47048 1004235 B ATOM 3969 OG SER B 47 -20134 I 390 39540 1005967 B ATOM 3885 CA GLU B 37 -12272 0689 48340 1004495 B ATOM 3970 C SER B 47 -20355 -1493 39185 1005862 B ATOM 3886 CB GLU B 37 -13225 -0028 49292 1007855 B ATOM 3971 O SER B 47 -19212 -1585 38751 1005576 B ATOM 3887 CG GLU B 37 -14669 0388 49105 1008558 B ATOM 3972 N GLU B 48 -21420 -2003 38563 1004209 B ATOM 3888 CD GLU B 37 -15663 -0555 49767 1008855 B ATOM 3973 CA GLU B 48 -21335 -2710 37288 1004658 B ATOM 3889 OEl GLU B 37 -15367 -1768 49875 1009198 B ATOM 3974 CB GLU B 48 -22737 -3030 36754 10015028 B ATOM 3890 OE2 GLU B 37 16754 0084 50159 1008911 B ATOM 3975 CG GLU B 48 -23640 -3829 37679 10015502 B ATOM 3891 C GLU B 37 -10992 -0124 48201 1004384 B ATOM 3976 CD GLU B 48 -23380 -5321 37617 10015937 B ATOM 3892 O GLU B 37 -10827 -0920 47270 1004630 B ATOM 3977 OEl GLU B 48 -22304 -5763 38075 100161 11 B ATOM 3893 N LEU B 38 -10075 0111 49126 1005143 B ATOM 3978 OE2 GLU B 48 -24255 -6053 37105 10015729 B ATOM 3894 CA LEU B 38 -8821 -0609 49153 1005347 B ATOM 3979 C GLU B 48 -20677 1734 36331 004517 B ATOM 3895 CB LEU B 38 -7654 0372 49296 1002947 B ATOM 3980 O GLU B 48 -20830 -0519 36486 005096 B ATOM 3896 CG LEU B 38 -6257 -0246 49265 1002738 B ATOM 3981 N GLY B 49 -19940 -2244 35348 004247 B ATOM 3897 CDl LEU B 38 -6132 -1 195 48088 1002576 B ATOM 3982 CA GLY B 49 -19333 1344 34388 1004013 B ATOM 3898 CD2 LEU B 38 -5218 0867 49201 1002425 B ATOM 3983 C GLY B 49 -18058 -1779 33712 1004214 B ATOM 3899 C LEU B 38 -8979 -1489 50386 1005374 B ATOM 3984 O GLY B 49 -17456 -2797 34047 1004498 B ATOM 3900 O LEU B 38 -8874 -1026 51526 1004735 B ATOM 3985 N LEU B 50 17668 -0972 32734 1004251 B ATOM 3901 N ARG B 39 -9262 -2762 50141 1004167 B ATOM 3986 CA LEU B 50 -16452 -1 166 31973 1004371 B ATOM 3902 CA ARG B 39 -9502 -3729 51207 1004820 B ATOM 3987 CB LEU B 50 -16643 -0561 30588 1003285 B ATOM 3903 CB ARG B 39 -10963 -4167 51 128 1006595 B ATOM 3988 CG LEU B 50 -16625 -1468 29359 1003398 B ATOM 3904 CG ARG B 39 -11461 -4949 52291 1007365 B ATOM 3989 CDl LEU B 50 -17129 -2856 29722 1003079 B ATOM 3905 CD ARG B 39 -12967 -5058 52210 1008226 B ATOM 3990 CD2 LEU B 50 -17473 -0833 28266 1003437 B ATOM 3906 NE ARG B 39 -13526 -5567 53461 1 008879 B ATOM 3991 C LEU B 50 -15357 -0409 32729 1004009 B ATOM 3907 CZ ARG B 39 -14822 -5543 53772 1008959 B ATOM 3992 O LEU B 50 -15542 0755 33081 1003881 B ATOM 3908 NHl ARG B 39 -15698 -5035 52914 1008807 B ATOM 3993 N TYR B 51 -14230 -1057 33000 1004131 B ATOM 3909 NH2 ARG B 39 -15240 -6008 54947 1009189 B ATOM 3994 CA TYR B 51 -13149 -0393 33723 1003996 B ATOM 3910 C ARG B 39 -8582 -4935 51083 1005025 B ATOM 3995 CB TYR B 51 -12985 -0958 35132 1004217 B ATOM 3911 O ARG B 39 -8462 -5527 50009 1005348 B ATOM 3996 CG TYR B 51 -14057 -0602 36124 1004227 B ATOM 3912 N ASP B 40 -7932 5298 52181 1005147 B ATOM 3997 CDl TYR B 51 -15320 -1 181 36064 1004313 B ATOM 3913 CA ASP B 40 -7018 -6435 52184 1004942 B ATOM 3998 CEl TYR B 51 -16298 -0858 36997 1004269 B ATOM 3914 CB ASP B 40 -7806 -7743 52124 10011309 B ATOM 3999 CD2 TYR B 51 -13799 0305 37144 1004383 B ATOM 3915 CG ASP B 40 -8836 -7853 53236 10011523 B ATOM 4000 CE2 TYR B 51 -14769 0634 38088 1004210 B ATOM 3916 ODl ASP B 40 -8455 -7696 54417 10011211 B ATOM 4001 CZ TYR B 51 -16015 0053 38009 1004180 B ATOM 3917 OD2 ASP B 40 -10025 -8098 52932 10011535 B ATOM 4002 OH TYR B 51 -16983 0387 38930 1004203 B ATOM 3918 C ASP B 40 -6034 -6369 51022 1004555 B ATOM 4003 C TYR B 51 -11806 -0540 33044 1004014 B ATOM 3919 O ASP B 40 -5690 -7392 50442 1004478 B ATOM 4004 O TYR B 51 -11498 1592 32453 1004103 B ATOM 3920 N ASN B 41 -5596 -5155 50685 1004992 B ATOM 4005 N LEU B 52 -11009 0523 33125 1003363 B ATOM 3921 CA ASN B 41 -4640 -4899 49609 1004567 B ATOM 4006 CA LEU B 52 -9657 0489 32597 1003528 B ATOM 3922 CB ASN B 41 -3381 -5738 49804 1005367 B ATOM 4007 CB LEU B 52 -9249 1 854 32039 1004987 B ATOM 3923 CG ASN B 41 -2161 -5094 49177 1004836 B ATOM 4008 CG LEU B 52 -7758 1992 31694 1004576 B ATOM 3924 ODl ASN B 41 -1835 -3934 49461 1004970 B ATOM 4009 CDl LEU B 52 -7298 0855 30802 1004779 B ATOM 3925 ND2 ASN B 41 -1480 -5839 48318 1004446 B ATOM 4010 CD2 LEU B 52 -7524 3315 31009 1004009 B ATOM 3926 C ASN B 41 -5185 -5125 48203 1004898 B ATOM 4011 C LEU B 52 -8821 0124 33834 1003681 B ATOM 3927 O ASN B 41 -4427 -5387 47262 1005049 B ATOM 4012 O LEU B 52 -8887 0806 34863 1003738 B ATOM 3928 N GLN B 42 -6498 -5010 48057 1003971 B ATOM 4013 N ILE B 53 -8082 -0976 33745 1003774 B ATOM 3929 CA GLN B 42 -7132 -5196 46763 1003763 B ATOM 4014 CA ILE B 53 -7258 -1448 34851 1003434 B ATOM 3930 CB GLN B 42 -7883 -6520 46724 1004806 B ATOM 4015 CB ILE B 53 -7606 -2895 35218 1003993 B ATOM 3931 CG GLN B 42 7072 7692 47218 1005015 B ATOM 4016 CG2 ILE B 53 6777 -3345 36383 1004057 B ATOM 3932 CD GLN B 42 -7862 -8983 47231 1004961 B ATOM 4017 CGl ILE B 53 -9087 -3013 35545 1003882 B ATOM 3933 OEl GLN B 42 -8997 -9029 47715 1004904 B ATOM 4018 CDl ILE B 53 -9503 -4422 35901 1003464 B ATOM 3934 NE2 GLN B 42 -7258-10047 46710 1005137 B ATOM 4019 C ILE B 53 -5812 -1426 34399 1003440 B ATOM 3935 C GLN B 42 -8115 -4068 46539 1003652 B ATOM 4020 O ILE B 53 5501 1812 33258 1003748 B ATOM 3936 O GLN B 42 -8692 -3535 47495 1003686 B ATOM 4021 N TYR B 54 4921 -0993 35279 1003686 B ATOM 3937 N LEU B 43 -8300 -3690 45278 1003881 B ATOM 4022 CA TYR B 54 -3511 -0944 34905 1003399 B ATOM 3938 CA LEU B 43 -9243 -2625 44951 1003739 ATOM 4023 CB TYR B 54 3235 0324 34096 1002766 B ATOM 3939 CB LEU B 43 -8822 -1915 43653 1002290 B ATOM 4024 CG TYR B 54 -3452 1593 34880 1002766 B ATOM 3940 CG LEU B 43 -7490 -1 174 43785 1002906 B ATOM 4025 CDl TYR B 54 -2434 2126 35667 1002766 B ATOM 3941 CDl LEU B 43 -7039 -0683 42433 1002915 B ATOM 4026 CEl TYR B 54 -2647 3252 36461 1002766 B 65251/C766

ATOM 4027 CD2TYRB 54 -4698 2219 34899 1002766 ATOM 4112 O PROB 65 23075-15942 39852 10012963 B ATOM 4028 CE2 TYR B 54 -4920 3355 35698 1002766 B ATOM 4113 N SERB 66 21586-1710641075 10017109 B ATOM 4029 CZ TYRB 54 -3886 3860 36470 1002766 B ATOM 4114 CA SERB 66 21982 -1840040544 10017469 B ATOM 4030 OH TYR B 54 -4086 4983 37227 1002766 B ATOM 4115 CB SERB 66 21950-19452 41657 10015834 B ATOM 4031 C TYRB 54 -2586 -1001 36111 1003258 B ATOM 4116 OG SERB 66 22304 -2073441167 10015550 B ATOM 4032 O TYRB 54 -2995 -0723 37248 1003143 B ATOM 4117 C SERB 66 21046-18812 39416 10017524 B ATOM 4033 N SER B 55 -1331 -1348 35858 1003655 B ATOM 4118 O SERB 66 20081 -18110 39110 10016866 B ATOM 4034 CA SERB 55 -0359 -1444 36932 1003633 B ATOM 4119 N THRB 67 21349 -19954 38807 10020084 B ATOM 4035 CB SERB 55 -0620 -269037769 1003468 B ATOM 4120 CA THRB 67 20565-20518 37711 10020084 B ATOM 4036 OG SERB 55 0414 -2891 38709 1004124 B ATOM 4121 CB THRB 67 19554-21571 38233 10017600 B ATOM 4037 C SERB 55 1047 -1517 36397 1003931 B ATOM 4122 OGlTHRB 67 20243-22545 39027 10017600 B ATOM 4038 O SERB 55 I 271 -2006 35290 1003645 B ATOM 4123 CG2THRB 67 18866-2227637066 10017600 B ATOM 4039 N GLN B 56 1993 -102037186 1004977 B ATOM 4124 C THR B 67 19798-19484 36891 10020084 B ATOM 4040 CA GLN B 56 3393 -1072 36812 1005047 B ATOM 4125 O THRB 67 20357 -18839 36004 10020084 B ATOM 4041 CB GLN B 56 3880 0233 36211 1006088 B ATOM 4126 N HISB 68 18514-19328 37199 10015858 B ATOM 4042 CG GLN B 56 5299 0076 35708 1006248 ATOM 4127 CA HIS B 68 17668-18395 36474 10015370 B ATOM 4043 CD GLN B 56 5972 1377 35389 1006560 ATOM 4128 CB HIS B 68 17039-19114 35279 10018411 B ATOM 4044 OEl GLN B 56 6443 2077 36290 1006513 B ATOM 4129 CG HIS B 68 16589-18199 34185 10018411 B ATOM 4045 NE2 GLN B 56 6026 1720 34101 1006871 B ATOM 4130 CD2 HIS B 68 15367-17992 33641 10018411 B ATOM 4046 C GLN B 56 4260 -1358 38012 1005295 B ATOM 4131 NDl HlSB 68 17456-17375 33502 10018411 B ATOM 4047 O GLN B 56 4073 -077039081 1005103 B ATOM 4132 CEl HIS B 68 16789-16700 32584 10018411 B ATOM 4048 N VAL B 57 5210 -226737836 1004684 B ATOM 4133 NE2HISB 68 15519-17056 32647 10018411 B ATOM 4049 CA VALB 57 6145 -2589 38903 1004121 B ATOM 4134 C HISB 68 16573-17846 37386 10014953 B ATOM 4050 CB VALB 57 5996 -403639404 1004352 B ATOM 4135 O HISB 68 16037-18565 38229 10014898 B ATOM 4051 CGlVALB 57 4583 -4263 39921 1004472 B ATOM 4136 N VALB 69 16248-16569 37214 10011157 B ATOM 4052 CG2VALB 57 6333 -4997 38291 1004045 B ATOM 4137 CA VALB 69 15211 -15920 38012 10011130 B ATOM 4053 C VALB 57 7526 -2417 38327 1004382 B ATOM 4138 CB VALB 69 15784-14738 38825 10010165 B ATOM 4054 O VALB 57 7720 -2566 37133 1004493 B ATOM 4139 CGl VALB 69 14694-14113 39672 10010141 B ATOM 4055 N LEU B 58 8482 -2080 39178 1004898 B ATOM 4140 CG2VALB 69 16924-15217 39707 1009991 B ATOM 4056 CA LEUB 58 9851 -1903 38732 1004743 B ATOM 4141 C VALB 69 14104-15392 37105 10011089 B ATOM 4057 CB LEUB 58 10305 -0460 38945 1005706 B ATOM 4142 O VALB 69 14375-14767 36079 10011445 B ATOM 4058 CG LEUB 58 11394 0068 38009 1005908 B ATOM 4143 N LEUB 70 12858-15659 37482 1007762 B ATOM 4059 CDl LEU B 58 12081 1247 38675 1005310 B ATOM 4144 CA LEU B 70 11711 -15196 36708 1007284 B ATOM 4060 CD2 LEU B 58 12399 1019 37691 1005686 B ATOM 4145 CB LEU B 70 10774-16354 36357 1006230 B ATOM 4061 C LEU B 55 10716 -282039568 1005040 B ATOM 4146 CG LEUB 70 11287-17404 35366 1006400 B ATOM 4062 O LEU B 58 10791 -2661 40785 1005203 B ATOM 4147 CDl LEUB 70 10183 -183S735077 1005904 B ATOM 4063 N PHEB 59 II 352 -3789 38918 1004765 B ATOM 4148 CD2 LEU B 70 11749 -16745 34072 1006460 B ATOM 4064 CA PHE B 59 12229 4717 39619 004855 B ATOM 4149 C LEU B 70 10925 -14155 37478 1007388 B ATOM 4065 CB PHEB 59 12131 -6113 39023 004779 B ATOM 4150 O LEUB 70 10660-14317 38666 1007399 B ATOM 4066 CG PHEB 59 10796 -6763 39209 004428 B ATOM 4151 N LEUB 71 10559-13083 36789 1006403 B ATOM 4067 CDl PHE B 59 9897 -685038148 004272 B ATOM 4152 CA LEU B 71 9787 -12009 37396 1006397 B ATOM 4068 CD2PHEB 59 10441 -7312 40434 1004624 B ATOM 4153 CB LEUB 71 10473-10659 37156 1005173 B ATOM 4069 CEl PHE B 59 8664 -7479 38310 1004864 B ATOM 4154 CG LEUB 71 11891 -10517 37710 1004940 B ATOM 4070 CE2PHEB 59 9212 -794040603 1004935 B ATOM 4155 CDl LEUB 71 12460 -9179 37298 1004555 B ATOM 4071 CZ PHE B 59 8325 -8023 39543 1004795 B ATOM 4156 CD2LEUB 71 11866 -10657 39220 1004952 B ATOM 4072 C PHEB 59 13673 -4234 39507 1005266 B ATOM 4157 C LEUB 71 8407 -12006 36752 1006800 B ATOM 4073 O PHEB 59 14072 -3658 38493 1005235 ATOM 4158 O LEUB 71 8288 11979 35524 1006749 B ATOM 4074 N LYS B 60 14447 -4466 40561 1006854 ATOM 4159 N THRB 72 7367-12058 37577 1004122 B ATOM 4075 CA LYS B 60 15847 -407640600 1006989 ATOM 4160 CA THRB 72 6008-12049 37051 1003865 B ATOM 4076 CB LYS B 60 16009 -272441289 1008685 B ATOM 4161 CB THRB 72 5281-13402 37254 1005566 B ATOM 4077 CG LYS B 60 17453 -229641466 1009304 B ATOM 4162 OGlTHRB 72 4853-13526 38614 1005819 B ATOM 4078 CD LYS B 60 17530 -0991 42229 10010125 B ATOM 4163 CG2THRB 72 6197-14554 36917 1005338 B ATOM 4079 CE LYS B 60 18964 -0551 42441 10010400 B ATOM 4164 C THRB 72 5170-10962 37701 1004128 B ATOM 4080 NZ LYS B 60 19009 077043132 10010434 B ATOM 4165 O THRB 72 5292 -10672 38900 1004232 B ATOM 4081 C LYS B 60 16635 -5131 41362 1006940 B ATOM 4166 N HIS B 73 4326-10348 36886 1003886 B ATOM 4082 O LYS B 60 16193 -5626 42399 1007215 B ATOM 4167 CA HIS B 73 3432 -930437348 1003931 B ATOM 4083 N GLY B 61 17804 -547740840 1008186 B ATOM 4168 CB HISB 73 3823 -7965 36744 1003300 B ATOM 4084 CA GLYB Sl 18625 -6468 41500 1008442 B ATOM 4169 CG HISB 73 3023 -6820 37269 1003587 B ATOM 4085 C GLY B 61 20089 6121 41396 1008612 B ATOM 4170 CD2HISB 73 2265 -6698 38386 1003763 B ATOM 4086 O GLY B 61 20527 -558440379 1008929 B ATOM 4171 NDl HIS B 73 2966 -5602 36632 1004048 B ATOM 4087 N GLN B 62 20839 -6411 42454 10010842 B ATOM 4172 CEl HIS B 73 2207 -4778 37332 I 003902 B ATOM 4088 CA GLNB 62 22272 -614642475 10010873 B ATOM 4173 NE2 HIS B 73 1770 -5418 38401 1003919 B ATOM 4089 CB GLN B 62 22752 -589743906 10011530 B ATOM 4174 C HISB 73 2076 -9722 36817 1003839 B ATOM 4090 CG GLN B 62 22039 4755 44619 10011943 B ATOM 4175 O HISB 73 1958-10110 35656 1003425 B ATOM 4091 CD GLN B 62 22302 -3404 43980 10012537 B ATOM 4176 N THRB 74 1048 -9668 37645 1004419 B ATOM 4092 OEl GLN B 62 21992 -3183 42810 10012497 B ATOM 4177 CA THR B 74 -0247-10086 37152 1005078 B ATOM 4093 NE2 GLN B 62 22875 -2489 44752 10012554 B ATOM 4178 CB THR B 74 -0333-11650 37132 1005078 B ATOM 4094 C GLN B 62 22940 -7389 41916 10010667 B ATOM 4179 OGl THRB 74 -1572-12081 37704 1005329 B ATOM 4095 O GLN B 62 22764 -8480 42451 10010818 B ATOM 4180 CG2THRB 74 0822-12271 37900 1005561 B ATOM 4096 N GLY B 63 23690 -7230 40831 1008945 B ATOM 4181 C THRB 74 -1421 -9479 37919 1004963 B ATOM 4097 CA GLY B 63 24361 -8370 40232 1008744 B ATOM 4182 O THRB 74 -1383 -9352 39140 1004521 B ATOM 4098 C GLYB 63 23380 -9480 39928 1008552 B ATOM 4183 N ILEB 75 -2456 -9079 37186 1003507 B ATOM 4099 O GLY B 63 22174 -9274 40009 1008356 B ATOM 4184 CA ILEB 75 -3651 -8502 37790 1003637 B ATOM 4100 N CYSB 64 23885-10663 39599 10014485 B ATOM 4185 CB ILEB 75 -4109 -7235 37037 1004198 B ATOM 4101 CA CYS B 64 23007 11778 39274 10014909 B ATOM 4186 CG2ILEB 75 -5425 -6723 37616 1004147 B ATOM 4102 C CYSB 64 23003-12971 40221 10015518 B ATOM 4187 CGl ILEB 75 -3020 -6164 37129 1003914 B ATOM 4103 O CYSB 64 24041-13373 40746 10015809 B ATOM 4188 CDl ILEB 75 -3377 -4859 36455 1004243 B ATOM 4104 CB CYS B 64 23295 -12260 37859 10014461 B ATOM 4189 C ILEB 75 -4748 -9552 37723 1003951 B ATOM 4105 SG CYS B 64 22485-11211 36622 10014582 B ATOM 4190 O ILEB 75 -5087-10037 36645 1003628 B ATOM 4106 N PROB 65 21812-13550 40453 10012401 B ATOM 4191 N SERB 76 -5291 -9902 38882 1004459 B ATOM 4107 CD PROB 65 20505-12956 40129 10014767 B ATOM 4192 CA SERB 76 -6331 -10915 38978 1004567 B ATOM 4108 CA PROB 65 21641 -14707 41334 10012635 B ATOM 4193 CB SERB 76 -5987 -11943 40052 1005942 B ATOM 4109 CB PROB 65 20126-14766 41541 10015020 B ATOM 4194 OG SER B 76 4751 -12566 39800 1006871 B ATOM 4110 CG PROB 65 19688-13350 41325 10014993 B ATOM 4195 C SERB 76 -7658 -10328 39346 1004167 B ATOM 4111 C PROB 65 22170 -15980 40687 10012936 B ATOM 4196 O SERB 76 7734 9277 39972 1003782 B 65251/C766

ATOM 4197 N ARGB 77 -8713-11027 38958 1003742 B ATOM 4282 ODl ASN B 87 -4049-14629 37475 1006857 B ATOM 4198 CA ARG B 77 -10064 -1062039314 1004260 B ATOM 4283 ND2 ASN B 87 -2646 -15547 35979 I 006292 B ATOM 4199 CB ARG B 77 -10932-10363 38071 1003577 B ATOM 4284 C ASN B 87 -6463 -1287434490 1005205 B ATOM 4200 CG ARG B 77 12426-10491 38373 1003795 B ATOM 4285 O ASN B 87 -6989-13443 33532 1005063 B ATOM 4201 CD ARG B 77 -13299 -9728 37415 1003882 B ATOM 4286 N LEUB 88 -6376-11544 34588 1004346 B ATOM 4202 NE ARG B 77 -14047 1057736489 1004126 B ATOM 4287 CA LEU B 88 -6888 -10664 33536 1004245 B ATOM 4203 CZ ARG B 77 -15374-10539 36353 1004469 B ATOM 4288 CB LEUB 88 -7559 -9441 34125 1003570 B ATOM 4204 NHl ARG B 77 -15986-11330 35483 1004478 B ATOM 4289 CG LEUB 88 -8777 -967034995 1003263 B ATOM 4205 NH2 ARG B 77 -16098 -9720 37102 1004455 B ATOM 4290 CDl LEU B 88 -9326 -8326 35404 1003340 B ATOM 4206 C ARG B 77 -10678-1176040116 1004094 B ATOM 4291 CD2LEUB 88 -9814-10465 34228 1003120 B ATOM 4207 O ARGB 77 -10547-12928 39751 1004669 B ATOM 4292 C LEU B 88 -5738-1018732671 1004169 B ATOM 4208 N ILEB 78 -11296-11435 41236 1003941 B ATOM 4293 O LEU B 88 -5845-10146 31447 1004016 B ATOM 4209 CA ILE B 78 -11978-12456 41999 1003810 B ATOM 4294 N LEU B 89 -4641 -9816 33331 1004760 B ATOM 4210 CB ILEB 78 -11369-12661 43449 1005084 B ATOM 4295 CA LEUB 89 -3442 -932732657 1004652 B ATOM 4211 CG2ILEB 78 -10017-1199043569 1005134 B ATOM 4296 CB LEUB 89 -3380 -7807 32755 1003401 B ATOM 4212 CGl ILEB 78 -12321 -1216744521 1005251 B ATOM 4297 CG LEUB 89 -4634 7065 32294 1003799 B ATOM 4213 CDl ILEB 78 -13529-13055 44711 1005283 B ATOM 4298 CDl LEU B 89 -4634 -5683 32893 1003772 B ATOM 4214 C ILEB 78 ^■ -13403-11883 41969 1004027 B ATOM 4299 CD2 LEU B 89 -4676 -6978 30784 1003711 B ATOM 4215 O ILEB 78 -13737-10910 42664 1003882 B ATOM 4300 C LEU B 89 -2233 -9929 33348 1004819 B ATOM 4216 N ALA B 79 -14222-12460 41090 1003945 B ATOM 4301 O LEU B 89 -2204-1002734579 1004891 B ATOM 4217 CA ALAB 79 -15587-1200440906 1003605 B ATOM 4302 N SER B 90 -1236 -1032432565 1005076 B ATOM 4218 CB ALAB 79 -16126-12543 39588 1007290 B ATOM 4303 CA SERB 90 -0043-10931 33133 1005010 B ATOM 4219 C ALAB 79 -16540-12356 42045 1003725 B ATOM 4304 CB SERB 90 -0325-12385 33498 1006174 B ATOM 4220 O ALA B 79 -16370-13362 42738 1003745 B ATOM 4305 OG SERB 90 0838 -13006 34007 1006596 B ATOM 4221 N VALB 80 -17555 11516 42229 1005602 B ATOM 4306 C SERB 90 1142-10897 32194 1004873 B ATOM 4222 CA VALB 80 -18550-1175043268 1005851 B ATOM 4307 O SER B 90 0989-11039 30983 1004855 B ATOM 4223 CB VALB 80 -19562 -1059443354 1005733 B ATOM 4308 N ALA B 91 2330-10727 32760 1004450 B ATOM 4224 CGl VALB 80 -20602 -10896 44412 1005573 B ATOM 4309 CA ALAB 91 3546-10701 31968 1004259 B ATOM 4225 CG2VALB 80 -18860 -9312 43678 1005903 B ATOM 4310 CB ALAB 91 3886 -9282 31595 I 003837 B ATOM 4226 C VALB 80 -19316-13029 42947 1006306 B ATOM 4311 C ALAB 91 4695 -11339 32744 1004656 B ATOM 4227 O VALB 80 -19732-13750 43838 1006165 B ATOM 4312 O ALA B 91 4664-1142033974 1004843 B ATOM 4228 N SER B 81 -19502-1330741666 1006661 B ATOM 4313 N ILEB 92 5706-11797 32018 1005788 B ATOM 4229 CA SERB 81 -20222 -14502 41253 1006947 B ATOM 4314 CA ILE B 92 6859 -12439 32632 1005786 B ATOM 4230 CB SERB 81 -21038 -14208 39995 1005024 B ATOM 4315 CB ILEB 92 6882-13944 32316 1004550 B ATOM 4231 OG SERB 81 -22027-13243 40274 1005328 B ATOM 4316 CG2ILEB 92 8016-14608 33071 1005157 B ATOM 4232 C SERB 81 -19330-15729 41013 1007365 B ATOM 4317 CGl ILEB 92 5542 -14578 32700 1004361 B ATOM 4233 O SERB 81 -19813-16757 40532 1007417 B ATOM 4318 CDl ILEB 92 5415-16022 32312 1004948 B ATOM 4234 N TYR B 82 -18042 -1562441349 1004347 B ATOM 4319 C ILEB 92 8113-11816 32060 1005769 B ATOM 4235 CA TYRB 82 -17098-1673241176 1004551 B ATOM 4320 O ILE B 92 8127-11427 30900 1005877 B ATOM 4236 CB TYRB 82 -16778-16931 39694 1003466 B ATOM 4321 N LYS B 93 9164-11724 32866 1007011 B ATOM 4237 CG TYRB 82 -16008-18201 39403 1003786 B ATOM 4322 CA LYS B 93 10416-11137 32403 1007076 B ATOM 4238 CDl TYR B 82 -14765-18159 38779 1004015 B ATOM 4323 CB LYS B 93 10452 -9644 32744 1008023 B ATOM 4239 CEl TYR B 82 -14036-19325 38551 1004194 B ATOM 4324 CG LYS B 93 11240 -879731759 1008392 B ATOM 4240 CD2TYRB 82 -16511 -1944639787 1003995 B ATOM 4325 CD LYS B 93 10763 -7343 31779 1008369 B ATOM 4241 CE2TYRB 82 -15788-20616 39562 1004142 B ATOM 4326 CE LYS B 93 11432 -6504 30683 1008359 B ATOM 4242 CZ TYRB 82 -14549 -20546 38947 1004211 B ATOM 4327 NZ LYS B 93 10958 -5081 30642 1008616 B ATOM 4243 OH TYRB 82 13809-21688 38750 1004053 B ATOM 4328 C LYS B 93 11595-11862 33042 1007246 B ATOM 4244 C TYR B 82 -15813-16443 41942 1004494 B ATOM 4329 O LYS B 93 11581 -12151 34238 1007038 B ATOM 4245 O TYRB 82 -14785-16133 41351 1004512 B ATOM 4330 N SER B 94 12606-12163 32231 1008570 B ATOM 4246 N GLN B 83 -15895-16551 43265 1005945 B ATOM 4331 CA SERB 94 13805 -12869 32687 1008815 B ATOM 4247 CA GLNB 83 -14775-16283 44167 1005934 B ATOM 4332 CB SER B 94 14124-14027 31736 1009433 B ATOM 4248 CB GLNB 83 -15176 -16575 45612 1007346 B ATOM 4333 OG SERB 94 14321-13566 30407 1009676 B ATOM 4249 CG GLNB 83 -15591-15373 46434 1007773 B ATOM 4334 C SERB 94 14994-11925 32742 1009074 B ATOM 4250 CD GLN B 83 -16985-14895 46107 1007877 B ATOM 4335 O SERB 94 15666-11706 31737 1009201 B ATOM 4251 OEl GLNB 83 -17567-1410746846 1007779 B ATOM 4336 N PROB 95 15287-11375 33929 1007532 B ATOM 4252 NE2 GLN B 83 -17530-1536744993 1007627 B ATOM 4337 CD PRO B 95 14698 -11756 35226 10010672 B ATOM 4253 C GLN B 83 -13480-17029 43906 1005752 B ATOM 4338 CA PRO B 95 16401 -10441 34120 1007926 B ATOM 4254 O GLN B 83 -13129-1791744664 1005497 B ATOM 4339 CB PRO B 95 16229-10004 35569 10010966 B ATOM 4255 N THR B 84 -12751-16673 42862 1005677 B ATOM 4340 CG PRO B 95 15731-11258 36217 10010711 B ATOM 4256 CA THRB 84 -11488-1734642590 1004914 B ATOM 4341 C PRO B 95 17762 11070 33863 1008369 B ATOM 4257 CB THR B 84 -11669-1864641784 1005777 B ATOM 4342 O PROB 95 18386 -10842 32824 1008712 B ATOM 4258 OGlTHRB 84 -12646-1947842415 1005832 B ATOM 4343 N CYS B 96 18223 -11858 34824 10017876 B ATOM 4259 CG2THRB 84 -10355-19393 41700 1006052 B ATOM 4344 CA CYS B 96 19504-12521 34700 10017855 B ATOM 4260 C THRB 84 -10648-16429 41748 1004565 B ATOM 4345 C CYSB 96 19368-13755 33831 10017965 B ATOM 4261 O THRB 84 -11 151-15791 40825 1004696 B ATOM 4346 O CYS B 96 18780-1475734240 10017995 B ATOM 4262 N LYS B 85 -9366 16355 42057 1003628 B ATOM 4347 CB CYS B 96 20032-12902 36078 10018931 B ATOM 4263 CA LYS B 85 -8485-15515 41279 1003614 B ATOM 4348 SG CYS B 96 20521 -11460 37072 10018931 B ATOM 4264 CB LYS B 85 -7075-15542 41859 1006983 B ATOM 4349 N GLN B 97 19907-13661 32621 10020084 B ATOM 4265 CG LYS B 85 6770 14463 42866 1006677 B ATOM 4350 CA GLN B 97 19872 -14758 31666 10020084 B ATOM 4266 CD LYS B 85 -5281 -14492 43182 1006517 B ATOM 4351 CB GLNB 97 20150-14223 30256 10014828 B ATOM 4267 CE LYS B 85 -4859-1331644051 1006347 B ATOM 4352 CG GLNB 97 19257-1305829854 10014828 B ATOM 4268 NZ LYS B 85 -5543-1331945374 1006172 B ATOM 4353 CD GLN B 97 19803-1228228668 10014828 B ATOM 4269 C LYS B 85 -8426-16027 39843 1003594 B ATOM 4354 OEl GLN B 97 20006 1283627588 10014828 B ATOM 4270 O LYS B 85 -8146-17199 39618 1003639 B ATOM 4355 NE2 GLN B 97 20043-10991 28867 10014828 B ATOM 4271 N VALB 86 -8733-15166 38880 1003330 B ATOM 4356 C GLNB 97 20939 -15779 32062 10020084 B ATOM 4272 CA VALB 86 -8613-15527 37473 1003619 B ATOM 4357 O GLN B 97 21675 -16279 31210 10020084 B ATOM 4273 CB VALB 86 -9986-15643 36734 1003545 B ATOM 4358 N ARG B 98 21017-16070 33361 10020081 B ATOM 4274 CGl VAL B 86 -10801-16756 37332 1004219 B ATOM 4359 CA ARG B 98 21983 -17022 33909 10020081 B ATOM 4275 CG2 VAL B 86 -10757-14355 36830 1003672 B ATOM 4360 CB ARG B 98 21939-18333 33106 10019941 B ATOM 4276 C VALB 86 -7774 -14380 36908 1003686 B ATOM 4361 CG ARG B 98 23014-19351 33463 10019941 B ATOM 4277 O VALB 86 -8048-1320737163 1004155 B ATOM 4362 CD ARG B 98 22889-1985034893 10019941 B ATOM 4278 N ASNB 87 -6723-14713 36179 1005655 B ATOM 4363 NE ARG B 98 24047-20651 35284 10019941 B ATOM 4279 CA ASN B 87 -5858-13686 35630 1005323 B ATOM 4364 CZ ARG B 98 24464-21735 34637 10019941 B ATOM 4280 CB ASN B 87 -4552-14319 35161 1006566 B ATOM 4365 NHl ARG B 98 25529-22396 35070 10019941 B ATOM 4281 CG ASNB 87 3726-14851 36305 1006596 B ATOM 4366 NH2 ARG B 98 23820-22161 33558 10019941 B 65251/C766

ATOM 4367 C ARG B 98 23409-16454 33935 10020081 B ATOM 4452 C TRP B 109 18402 -3817 37132 1006586 B ATOM 4368 O ARG B 98 24351 -17136 34342 10020081 B ATOM 4453 O TRP B 109 17922 -4023 38248 1006747 B ATOM 4369 N GLU B 99 23559-15199 33516 10019303 B ATOM 4454 N TYR B I lO 17757 -3 184 36159 1006859 B ATOM 4370 CA GLU B 99 24865-14539 33492 10019303 B ATOM 4455 CA TYR B I lO 16404 -2687 36327 1006723 B ATOM 4371 CB GLU B 99 24703-13017 33363 10016568 B ATOM 4456 CB TYR B I lO 16372 -1 165 36209 1006962 B ATOM 4372 CG GLU B 99 23269-12510 33469 10016568 B ATOM 4457 CG TYR B 110 17153 -0438 37276 1007317 B ATOM 4373 CD GLU B 99 22534-12553 32143 10016568 B ATOM 4458 CDl TYR B 110 18548 -0429 37273 1007726 B ATOM 4374 OEl GLU B 99 22656-13571 31430 10016568 B ATOM 4459 CEl TYR B 1 10 19263 0285 38234 1007758 B ATOM 4375 OE2 GLU B 99 21 829 11572 31818 10016568 B ATOM 4460 CD2 TYR B 110 16494 0275 38268 1007340 B ATOM 4376 C GLU B 99 25690-14849 34740 10019303 B ATOM 4461 CE2 TYR B 110 17197 0988 39233 1007877 B ATOM 4377 O GLU B 99 26850-15245 34636 10019303 B ATOM 4462 CZ TYR B I lO 18575 0993 39211 1007906 B ATOM 4378 N THR B lOO 25082-14666 35910 10020084 B ATOM 4463 OH TYR B I lO 19247 1723 40163 1008026 B ATOM 4379 CA THR B lOO 25736-14912 37195 10020084 B ATOM 4464 C TYR B I lO 15518 -3296 35256 1006574 B ATOM 4380 CB THR B 100 25852-16429 37488 10016634 B ATOM 4465 O TYR B 110 15916 -3402 34098 1006693 B ATOM 4381 OGl THR B 100 26536-17077 36410 10016662 B ATOM 4466 N GLU B i l l 14313 -3695 35649 1006277 B ATOM 4382 CG2 THR B 100 24473-17051 37649 10016751 B ATOM 4467 CA GLU B i l l 13366 -4298 34721 1006079 B ATOM 4383 C THR B lOO 27128 -14278 37275 10020084 B ATOM 4468 CB GLU B i l l 13503 -5818 34771 1007665 B ATOM 4384 O THR B lOO 28041 14657 36541 10020084 B ATOM 4469 CG GLU B i l l 13431 -6482 33426 1008357 B ATOM 4385 N PRO B lOl 27304-13301 38179 10020084 B ATOM 4470 CD GLU B i l l 14534 -6020 32505 1008854 B ATOM 4386 CD PRO B 101 26311-12832 39164 10010621 B ATOM 4471 OEl GLU B 111 15712 -6209 32866 1008875 B ATOM 4387 CA PRO B 101 28579-12604 38364 10020084 B ATOM 4472 OE2 GLU B i l l 14226 -5466 31424 1009570 B ATOM 4388 CB PRO B lOl 28395-11915 39712 10010716 B ATOM 4473 C GLU B i l l 11934 -3892 35080 1006137 B ATOM 4389 CG PRO B 101 26944-11559 39686 10010519 B ATOM 4474 O GLU B i l l 11399 -4309 36110 1006673 B ATOM 4390 C PRO B 101 29791 -13533 38342 10020084 B ATOM 4475 N PRO B 112 11305 -3042 34250 1005383 B ATOM 4391 O PRO B 101 29985 -14342 39250 10020084 B ATOM 4476 CD PRO B 112 11940 -2192 33226 1004062 B ATOM 4392 N GLU B 102 30596-13405 37292 10020084 B ATOM 4477 CA PRO B 112 9930 -2595 34494 1005306 B ATOM 4393 CA GLU B 102 31800-14211 37117 10020084 B ATOM 4478 CB PRO B 112 9950 -1 168 33978 1003669 B ATOM 4394 CB GLU B 102 32644-13618 35979 10012328 B ATOM 4479 CG PRO B 112 10780 -1303 32764 1003782 B ATOM 4395 CG GLU B 102 33982-14304 35728 10012448 B ATOM 4480 C PRO B 112 8917 -3450 33727 1005009 B ATOM 4396 CD GLU B 102 35020-13991 36795 10012579 B ATOM 4481 O PRO B 112 9254 -4076 32717 1005022 B ATOM 4397 OEl GLU B 102 35347 12798 36987 10012660 B ATOM 4482 N ILE B 113 7684 -3488 34216 1004131 B ATOM 4398 OE2 GLU B 102 35509-14941 37440 10012491 B ATOM 4483 CA ILE B 1 13 6623 -423S 33545 1004328 B ATOM 4399 C GLU B 102 32624-14303 38406 10020084 B ATOM 4484 CB ILE B 113 6375 -5611 34184 1005381 B ATOM 4400 O GLU B 102 33169-15360 38728 10020012 B ATOM 4485 CG2 ILE B 113 5246 -6318 33453 1004983 B ATOM 4401 N GLY B 103 32706-13197 39140 10017310 B ATOM 4486 CGl ILE B 113 7635 -6462 34115 1005087 B ATOM 4402 CA GLY B 103 33466-13 174 40379 10017042 B ATOM 4487 CDl ILE B 113 7420 -7882 34616 1005135 B ATOM 4403 C GLY B 103 34053-11 801 40649 10016829 B ATOM 4488 C ILE B 113 5320 -3459 33635 1004750 B ATOM 4404 O GLY B 103 34547-11 527 41744 1 0016278 B ATOM 4489 O ILE B 113 4910 3058 34727 1005090 B ATOM 4405 N ALA B 104 33997-10935 39640 10018749 B ATOM 4490 N TYR B 114 4676 -3235 32493 1003663 B ATOM 4406 CA ALA B 104 34516 -9577 39746 10018749 B ATOM 4491 CA TYR B 114 3402 -2519 32486 1003491 B ATOM 4407 CB ALA B 104 35877 -9485 39058 1009677 B ATOM 4492 CB TYR B 114 3454 1329 31534 1003903 B ATOM 4408 C ALA B 104 33537 8592 39110 10018749 B ATOM 4493 CG TYR B 114 2251 -0421 31640 1003689 B ATOM 4409 O ALA B 104 33300 -8645 37903 10018749 B ATOM 4494 CDl TYR B 114 2198 0582 32605 10041 18 B ATOM 4410 N GLU B 105 32975 -7708 39937 10018154 B ATOM 4495 CEl TYR B 114 1086 1418 32716 1004075 B ATOM 4411 CA GLU B 105 32014 -6678 39520 10018154 B ATOM 4496 CD2 TYR B 114 1 154 -0571 30779 1003706 B ATOM 4412 CB GLU B 105 32177 -6332 38033 1 0019972 B ATOM 4497 CE2 TYR B 114 0040 0257 30884 1004139 B ATOM 4413 CG GLU B 105 33481 -5635 37689 10019972 B ATOM 4498 CZ TYR B 114 0019 1253 31859 1004147 B ATOM 4414 CD GLU B 105 33639 -4316 38415 10019972 B ATOM 4499 OH TYR B 114 -1061 2096 31983 1004097 B ATOM 4415 OEl GLU B 105 33727 -4330 39661 10019972 B ATOM 4500 C TYR B 114 2276 -3460 32059 1003475 B ATOM 4416 OE2 GLU B 105 33671 3264 37741 10019849 B ATOM 4501 O TYR B 114 2460 -4320 31206 1003766 B ATOM 4417 C GLU B 105 30553 -7036 39793 10018154 B ATOM 4502 N LEU B 115 1 114 -3284 32666 1003795 B ATOM 4418 O GLU B 105 30171 -7271 40940 10018154 B ATOM 4503 CA LEU B 115 -0057 -4100 32374 1003699 B ATOM 4419 N ALA B 106 29749 7057 38729 10016264 B ATOM 4504 CB LEU B 115 -0258 -5115 33496 1005009 B ATOM 4420 CA ALA B 106 28318 -7368 38785 10016264 B ATOM 4505 CG LEU B 115 0013 -6603 33275 1005334 B ATOM 4421 CB ALA B 106 28037 -8443 39844 1004535 B ATOM 4506 CDl LEU B 115 1210 -6821 32371 1005172 B ATOM 4422 C ALA B 106 27474 -6119 39056 10016264 B ATOM 4507 CD2 LEU B 115 0225 -7251 34644 1005664 B ATOM 4423 O ALA B 106 27079 -5853 40191 10016264 B ATOM 4508 C LEU B 115 -1286 -3192 32289 1003943 B ATOM 4424 N LYS B 107 27202 -5359 37997 10013843 B ATOM 4509 O LEU B 115 -1431 -2252 33087 1004196 B ATOM 4425 CA LYS B 107 26405 -4135 38089 10013255 B ATOM 4510 N GLY B 116 -2168 -3457 31328 1003521 B ATOM 4426 CB LYS B 107 26462 -3361 36765 10019021 B ATOM 4511 CA GLY B 116 -3356 2629 31221 1002955 B ATOM 4427 CG LYS B 107 27755 -2601 36497 10019016 B ATOM 4512 C GLY B 116 -4337 -3085 30175 1003340 B ATOM 4428 CD LYS B 107 28949 -3524 36334 10019159 B ATOM 4513 O GLY B 116 -3931 -3534 29117 1003228 B ATOM 4429 CE LYS B 107 30173 -2745 35874 10018763 B ATOM 4514 N GLY B 117 5628 -2948 30475 10031 11 B ATOM 4430 NZ LYS B 107 30490 -1601 36774 10018789 B ATOM 4515 CA GLY B 117 -6681 -3362 29558 1003411 B ATOM 4431 C LYS B 107 24943 -4435 38420 10012803 B ATOM 4516 C GLY B 117 -8042 -2977 30103 I 003542 B ATOM 4432 O LYS B 107 24511 -5585 38368 10012716 B ATOM 4517 O GLY B 117 -8158 -2539 31259 1003680 B ATOM 4433 N PRO B 108 24163 -3397 38770 1009829 B ATOM 4518 N VAL B 118 -9076 -3132 29277 1003874 B ATOM 4434 CD PRO B 108 24581 -2013 39066 1007518 B ATOM 4519 CA VAL B 1 18 -10449 -2786 29670 1004152 B ATOM 4435 CA PRO B 108 22749 -3585 39099 1009703 B ATOM 4520 CB VAL B 118 -11 138 -1979 28562 1002939 B ATOM 4436 CB PRO B 108 22441 -2363 39965 1007433 B ATOM 4521 CGl VAL B 118 -12576 -1677 28937 1003079 B ATOM 4437 CG PRO B 108 23254 -1307 39316 1007171 B ATOM 4522 CG2 VAL B 118 -10371 -0692 28341 1002945 B ATOM 4438 C PRO B 108 21 899 -3631 37828 1009626 B ATOM 4523 C VAL B 118 -11248 -4047 29974 1003943 B ATOM 4439 O PRO B 108 22330 -3165 36773 1009444 B ATOM 4524 O VAL B 118 -11 160 -5024 29238 1004338 B ATOM 4440 N TRP B 109 20703 -4208 37928 1006680 B ATOM 4525 N PHE B 119 -12015 -4017 31068 1003853 B ATOM 4441 CA TRP B 109 19804 -4285 36783 1006425 B ATOM 4526 CA PHE B 119 -12798 -5178 31496 1003984 B ATOM 4442 CB TRP B 109 19728 -5710 36230 1007773 B ATOM 4527 CB PHE B 119 -12015 5950 32566 1003855 B ATOM 4443 CG TRP B 109 19348 -6743 37239 1007742 B ATOM 4528 CG PHE B 119 -10701 -6494 32087 1003615 B ATOM 4444 CD2 TRP B 109 18025 -7092 37663 1007643 B ATOM 4529 CDl PHE B 119 -9560 -5701 32087 1003434 B ATOM 4445 CE2 TRP B 109 18150 -8134 38606 1007568 B ATOM 4530 CD2 PHE B 119 10616 -7792 31575 1003483 B ATOM 4446 CE3 TRP B 109 16746 -6627 37338 1007653 B ATOM 4531 CEl PHE B 119 -S 341 -6193 31571 1003541 B ATOM 4447 CDl TRP B 109 20192 -7556 37925 1007452 B ATOM 4532 CE2 PHE B 119 -9411 -8290 31060 1003564 B ATOM 4448 NEl TRP B 109 19484 -8398 38747 1007284 B ATOM 4533 CZ PHE B 119 -8273 -7489 31056 1003473 B ATOM 4449 CZ2 TRP B 109 17047 -8722 39229 1007213 B ATOM 4534 C PHE B 119 -14197 .4880 32046 1004075 B ATOM 4450 CZ3 TRP B 109 15643 -7212 37961 1007629 B ATOM 4535 O PHE B 119 -14442 -3820 32620 1003685 B ATOM 4451 CH2 TRP B 109 15805 -8250 38896 1007193 B ATOM 4536 N GLN B 120 -15107 -5836 31 868 1004295 B 65251/C766

ATOM 4537 CA GLN B 120 16480 -5738 32374 1004632 B ATOM 4622 N ILEB 131 3015 -9637 42490 1004962 B ATOM 4538 CB GLNB 120 -17401 -6655 31586 1006174 B ATOM 4623 CA ILE B 131 4286 -9995 41866 1005216 B ATOM 4539 CG GLN B 120 18556 -5974 30894 1006189 B ATOM 4624 CB ILE B 131 5341 -887941996 1005336 B ATOM 4540 CD GLN B 120 -19397 -514831830 1006149 B ATOM 4625 CG2ILEB131 4920 -767441186 1005359 B ATOM 4541 OEl GLN B 120 -19683 -5564 32946 1006105 B ATOM 4626 CGl ILEB 131 5538 -8525 43468 1004955 B ATOM 4542 NE2 GLN B 120 -19818 -3969 31373 1006432 B ATOM 4627 CDl ILEB 131 6610 -7491 43703 1004816 B ATOM 4543 C GLN B 120 -16407 -6251 33806 1004546 B ATOM 4628 C ILE B 131 4792-11218 42604 1005405 B ATOM 4544 O GLN B 120 -15990 -7382 34013 1004816 B ATOM 4629 O ILE B 131 4335 -11508 43707 1005477 B ATOM 4545 N LEU B 121 -16805 -5439 34784 1003679 B ATOM 4630 N ASN B 132 5744-1192642011 1006842 B ATOM 4546 CA LEUB 121 -16745 -5829 36190 1003845 B ATOM 4631 CA ASN B 132 6284-1312442641 1006542 B ATOM 4547 CB LEU B 121 -15736 -4948 36930 1003959 B ATOM 4632 CB ASN B 132 6543-14169 41571 1005292 B ATOM 4548 CG LEUB 121 -14286 -541737055 1003786 B ATOM 4633 CG ASNB 132 7632-13751 40622 I 005162 B ATOM 4549 CDl LEU B 121 -13885 -6279 35881 1003925 B ATOM 4634 ODl ASN B 132 7694-1259740203 1005331 B ATOM 4550 CD2LEUB121 -13390 -418437182 1003335 B ATOM 4635 ND2ASNB132 8503 -1468740272 1004945 B ATOM 4551 C LEU B 121 -18090 -5723 36891 1004049 B ATOM 4636 C ASN B 132 7569 -1289043454 1006307 B ATOM 4552 O LEU B 121 -18920 -4880 36525 1004576 B ATOM 4637 O ASN B 132 7842-13627 44398 1006624 B ATOM 4553 N GLU B 122 -18292 -6577 37901 1004364 B ATOM 4638 N ARG B 133 8351 -1187043097 1006467 B ATOM 4554 CA GLUB 122 19524 -6604 38698 1004518 B ATOM 4639 CA ARG B 133 9599 -1158043804 1006026 B ATOM 4555 CB GLU B 122 19888 -8022 39136 1009693 B ATOM 4640 CB ARG B 133 10785-1172742846 1006724 B ATOM 4556 CG GLUB 122 -20142 -9051 38067 1009997 B ATOM 4641 CG ARG B 133 10955 -1312442282 1006982 B ATOM 4557 CD GLUB 122 -20369-10438 38678 10010525 B ATOM 4642 CD ARG B 133 11108-14145 43393 1007506 B ATOM 4558 OEl GLU B 122 -19435-10963 39331 10010675 B ATOM 4643 NE ARGB 133 12257-1387444254 1007292 B ATOM 4559 OE2GLUB122 -21480-10996 38517 10010534 B ATOM 4644 CZ ARG B 133 13531-14037 43893 1007402 B ATOM 4560 C GLU B 122 -19317 -5816 39984 1004398 B ATOM 4645 NHl ARG B 133 14508-13763 44752 1007670 B ATOM 4561 O GLU B 122 -18201 -5738 40489 1004517 B ATOM 4646 NH2ARGB133 13836 14478 42678 1007331 B ATOM 4562 N LYS B 123 -20392 -5252 40525 1004569 B ATOM 4647 C ARG B 133 9632-10194 44444 1006485 B ATOM 4563 CA LYS B 123 -20288 -453041781 1004654 B ATOM 4648 O ARG B 133 10403 -9331 44037 1006721 B ATOM 4564 CB LYS B 123 -21647 -398242208 1006286 B ATOM 4649 N PRO B 134 8811 -9973 45477 I 005003 B ATOM 4565 CG LYS B 123 -21653 -3421 43607 1005902 B ATOM 4650 CD PRO B 134 7978-10957 46183 1003720 B ATOM 4566 CD LYS B 123 -23036 -2985 44015 1005669 B ATOM 4651 CA PRO B 134 8758 -868446163 1005375 B ATOM 4567 CE LYS B 123 -23038 -2497 45453 1005842 B ATOM 4652 CB PRO B 134 7705 -8915 47244 1003992 B ATOM 4568 NZ LYS B 123 -24406 -2122 45920 1006243 B ATOM 4653 CG PRO B 134 7876 -10344 47559 1004192 B ATOM 4569 C LYS B 123 -19813 -5554 42798 1004736 B ATOM 4654 C PROB 134 10092 -825746739 1005893 B ATOM 4570 O LYS B 123 -20403 -6625 42933 1005212 B ATOM 4655 O PRO B 134 10259 -710747145 1006197 B ATOM 4571 N GLY B 124 -18731 -5238 43495 1004161 B ATOM 4656 N ASPB 135 11045 -917946781 1007246 B ATOM 4572 CA GLYB 124 -18208 -615444486 1004272 B ATOM 4657 CA ASP B 135 12360 -885047311 1006892 B ATOM 4573 C GLY B 124 -16964 -692644080 1004413 B ATOM 4658 CB ASP B 135 13095-10131 47711 1009213 B ATOM 4574 O GLY B 124 -16357 -7591 44925 1004493 B ATOM 4659 CG ASP B 135 12931 -11232 46695 1009160 B ATOM 4575 N ASPB 125 -16578 -686442807 1004270 B ATOM 4660 ODl ASP B 135 13576-1115445633 1008754 B ATOM 4576 CA ASP B 125 -15387 -7579 42358 1004149 B ATOM 4661 OD2ASPB 135 12148-1217046950 1009318 B ATOM 4577 CB ASP B 125 -15226 -7453 40847 1006129 B ATOM 4662 C ASP B 135 13179 -8028 46310 1006763 B ATOM 4578 CG ASP B 125 -16254 -825440075 1006675 B ATOM 4663 O ASP B 135 14198 -7443 46670 1007432 B ATOM 4579 ODl ASP B 125 -16970 -907240688 1006840 B ATOM 4664 N TYRB 136 12715 -7975 45060 1005947 B ATOM 4580 OD2ASPB125 -16334 -8072 38844 1006541 B ATOM 4665 CA TYR B 136 13384 -7214 44015 1006068 B ATOM 4581 C ASPB 125 -14119 -7062 43045 1004054 B ATOM 4666 CB TYR B 136 13493 -8030 42738 1008006 B ATOM 4582 O ASP B 125 -14022 -5876 43386 1003745 B ATOM 4667 CG TYR B 136 14527 -9121 42773 1007967 B ATOM 4583 N ARG B 126 -13155 -7956 43248 1005179 B ATOM 4668 CDl TYR B 136 14162-10453 42581 1007927 B ATOM 4584 CA ARG B 126 -11897 -7613 43895 1004727 B ATOM 4669 CEl TYR B 136 15114-1147042547 1008182 B ATOM 4585 CB ARG B 126 -11636 -855245071 1008206 B ATOM 4670 CD2TYRB 136 15875 -8828 42941 1008184 B ATOM 4586 CG ARG B 126 -12551 -837946266 1008055 B ATOM 4671 CE2TYRB136 16840 -9841 42909 1008131 B ATOM 4587 CD ARG B 126 -12349 -9522 47256 1008547 B ATOM 4672 CZ TYR B 136 16449-1116042708 1008261 B ATOM 4588 NE ARG B 126 -12931 -921448556 1008902 B ATOM 4673 OH TYR B 136 17386-12171 42650 1008645 B ATOM 4589 CZ ARG B 126 -12370 -841049462 1009225 B ATOM 4674 C TYRB 136 12616 -5935 43703 1006259 B ATOM 4590 NHl ARG B 126 -12979 -8180 50625 1009192 B ATOM 4675 O TYRB 136 12956 -520442778 1006547 B ATOM 4591 NH2ARGB126 -11189 -7850 49221 1009044 B ATOM 4676 N LEU B 137 11580 -5658 44479 1007208 B ATOM 4592 C ARG B 126 -10755 -774642900 1004811 B ATOM 4677 CA LEU B 137 10772 -4470 44258 1006879 B ATOM 4593 O ARG B 126 -10578 -8798 42297 1004533 B ATOM 4678 CB LEU B 137 9558 -450745177 1006828 B ATOM 4594 N LEU B 127 -9967 -6692 42732 1003862 B ATOM 4679 CG LEU B 137 8185 -449744515 1006601 B ATOM 4595 CA LEU B 127 8844 -672941800 1003500 B ATOM 4680 CDl LEU B 137 7138 -425645588 1006815 B ATOM 4596 CB LEU B 127 -8891 -5509 40887 1003487 B ATOM 4681 CD2LEUB 137 8107 -3412 43462 1006977 B ATOM 4597 CG LEU B 127 -10172 -5431 40052 1003385 B ATOM 4682 C LEU B 137 11511 -3151 44480 1006816 B ATOM 4598 CDl LEUB 127 -10291 -407039393 1003443 B ATOM 4683 O LEU B 137 11946 -2873 45589 1006701 B ATOM 4599 CD2LEUB 127 -10153 -6525 38999 1003451 B ATOM 4684 N LEU B 138 11648 -233443439 1007227 B ATOM 4600 C LEU B 127 -7535 -676642563 1003475 B ATOM 4685 CA LEU B 138 12298 -103443603 1007007 B ATOM 4601 O LEUB 127 -7367 -6040 43536 1003095 B ATOM 4686 CB LEU B 138 13247 -069642442 1006475 B ATOM 4602 N SER B 128 -6611 -7618 42120 1004334 B ATOM 4687 CG LEU B 138 13695 078442460 1006087 B ATOM 4603 CA SER B 128 -5306 -7771 42772 1004301 B ATOM 4688 CDl LEUB 138 14164 1157 43854 1006244 B ATOM 4604 CB SER B 128 -5140 -9182 43332 1007311 B ATOM 4689 CD2LEUB138 14791 1043 41450 1006379 B ATOM 4605 OG SER B 128 -6335 -9650 43924 1007896 B ATOM 4690 C LEU B 138 11262 0069 43699 1007342 B ATOM 4606 C SER B 128 -4179 -7529 41789 1004219 B ATOM 4691 O LEU B 138 10765 0554 42685 1007257 B ATOM 4607 O SER B 128 -4252 -7941 40639 1004347 B ATOM 4692 N PHE B 139 10935 0465 44919 1005755 B ATOM 4608 N ALA B 129 -3138 -6851 42252 1005095 B ATOM 4693 CA PHE B 139 9963 152945125 I 005893 B ATOM 4609 CA ALA B 129 -1975 -6572 41431 1005192 B ATOM 4694 CB PHE B 139 8763 1009 45937 1008864 B ATOM 4610 CB ALA B 129 -1812 -506741249 1002661 B ATOM 4695 CG PHE B 139 9137 0162 47125 1008779 B ATOM 4611 C ALAB 129 0816 7160 42228 1005069 B ATOM 4696 CDl PHE B 139 8269 -082247581 1008732 B ATOM 4612 O ALA B 129 -0322 -6545 43167 1005157 B ATOM 4697 CD2 PHE B 139 10345 034747794 1009040 B ATOM 4613 N GLUB 130 -0390 -8362 41860 1004343 B ATOM 4698 CEl PHE B 139 8593 -1609 48679 1009196 B ATOM 4614 CA GLU B 130 0672 -9039 42588 1004440 B ATOM 4699 CE2PHEB139 10679 -043448894 1008794 B ATOM 4615 CB GLU B 130 0107-10328 43189 1008961 B ATOM 4700 CZ PHEB 139 9801 -1415 49338 1009188 B ATOM 4616 CG GLU B 130 1059-10083 44132 1008915 B ATOM 4701 C PHE B 139 10657 2682 45834 1006296 B ATOM 4617 CD GLU B 130 -1948-11301 44326 1009464 B ATOM 4702 O PHE B 139 10087 333246710 1006306 B ATOM 4618 OEl GLUB 130 -2903-1121245133 1009601 B ATOM 4703 N ALA B 140 11899 2930 45428 1006083 B ATOM 4619 OE2 GLUB 130 -1704 -1233843674 1009445 B ATOM 4704 CA ALA B 140 12721 3983 46018 1006213 B ATOM 4620 C GLU B 130 1927 -9352 41777 1004079 B ATOM 4705 CB ALA B 140 14206 369745757 1005463 B ATOM 4621 O GLU B 130 1919 -931740540 1004071 B ATOM 4706 C ALA B 140 12376 5368 45512 1006252 B 65251/C766

ATOM 4707 O ALA B 140 12253 6302 46302 1006441 B ATOM 4792 CA LEU B 152 -15234 4208 31646 1007108 ATOM 4708 N GLU B 141 12222 5497 44196 1007955 B ATOM 4793 CB LEU B 152 -14331 3591 30585 1005353 ATOM 4709 CA GLU B 141 11925 6785 43594 1008273 B ATOM 4794 CG LEU B 152 -12844 3766 30866 1005478 ATOM 4710 CB GLU B 141 12138 6736 42077 10020043 B ATOM 4795 CDl LEU B 152 -12027 3083 29794 1005247 B ATOM 4711 CG GLU B 141 11983 8090 41381 10020043 B ATOM 4796 CD2 LEU B 152 -12513 5221 30920 1005398 B ATOM 4712 CD GLU B 141 10539 8435 41043 10020043 B ATOM 4797 C LEU B 152 -16693 4051 31243 007393 B ATOM 4713 OEl GLU B 141 10221 9638 40942 10020043 B ATOM 4798 O LEU B 152 -17448 5025 31233 007979 B ATOM 4714 OE2 GLU B 141 9724 7508 40863 10020043 B ATOM 4799 N ILE B 153 2463 9916 61583 1003910 B ATOM 4715 C GLU B 141 10535 7309 43899 1008483 B ATOM 4800 CA ILE B 153 3519 10924 61567 1003910 B ATOM 4716 O GLU B 141 10379 8132 44794 I 008851 B ATOM 4801 CB ILE B 153 4580 10624 60490 1002777 B ATOM 4717 N SER B 142 9521 6847 43175 10010881 B ATOM 4802 CG2 ILE B 153 5355 9382 60856 1002455 B ATOM 4718 CA SER B 142 8182 7365 43416 10011180 B ATOM 4803 CGl ILE B 153 3907 10457 59131 1002455 B ATOM 4719 CB SER B 142 8218 8883 43268 1004790 B ATOM 4804 CDl ILE B 153 4881 10158 58010 1002455 B ATOM 4720 OG SER B 142 7078 9486 43839 1004878 B ATOM 4805 C ILE B 153 2965 12330 61347 1003910 B ATOM 4721 C SER B 142 7106 6784 42495 100113 12 B ATOM 4806 O ILE B 153 I 879 12521 60804 1003910 B ATOM 4722 O SER B 142 6333 5905 42895 10011821 B ATOM 4807 N THR B 154 3750 13310 61774 1004397 B ATOM 4723 N GLY B 143 7038 7287 41268 1005455 B ATOM 4808 CA THR B 154 3364 14705 61713 1004397 B ATOM 4724 CA GLY B 143 6040 6770 40354 1005202 B ATOM 4809 CB THR B 154 2787 15103 63093 1004369 B ATOM 4725 C GLY B 143 6527 5530 39625 1005009 B ATOM 4810 OG I THR B 154 1360 15135 63011 1005397 B ATOM 4726 O GLY B 143 6232 5353 38447 1005208 B ATOM 4811 CG2 THR B 154 3352 16458 63579 1005397 B ATOM 4727 N GLN B 144 7263 4670 40324 1005092 B ATOM 4812 C THR B 154 4494 15665 61349 1004397 B ATOM 4728 CA GLN B 144 7813 3447 39740 1004545 B ATOM 4813 O THR B 154 5649 15458 61729 1004397 B ATOM 4729 CB GLN B 144 9191 3162 40332 1007576 B ATOM 4814 N LEU B 155 4149 16710 60604 1004089 B ATOM 4730 CG GLN B 144 10110 4367 40365 1007504 B ATOM 4815 CA LEU B 155 5104 17757 60242 1004089 B ATOM 4731 CD GLN B 144 11515 4026 40832 1007501 B ATOM 4816 CB LEU B 155 5530 17662 58773 1004104 B ATOM 4732 OEl GLN B 144 11698 3362 41852 1008058 B ATOM 4817 CG LEU B 155 6594 18694 58351 1003762 B ATOM 4733 NE2 GLN B 144 12517 4495 40093 1007355 B ATOM 4818 CDl LEU B 155 7798 18596 59273 1003762 B ATOM 4734 C GLN B 144 6936 2223 39954 1004725 B ATOM 4819 CD2 LEU B 155 7014 18457 56910 1003762 B ATOM 4735 O GLN B 144 7052 1245 39232 1004956 B ATOM 4820 C LEU B 155 4411 19103 60496 1004089 B ATOM 4736 N VAL B 145 6071 2268 40960 1004792 B ATOM 4821 O LEU B 155 3403 19424 59857 1004089 B ATOM 4737 CA VAL B 145 5189 1 150 41255 1004617 B ATOM 4822 N LYS B 156 4939 19882 61437 1004091 B ATOM 4738 CB VAL B 145 5719 0352 42462 1004627 B ATOM 4823 CA LYS B 156 4329 21 157 61773 1004091 B ATOM 4739 CGl VAL B 145 4827 -0846 42745 1004443 B ATOM 4824 CB LYS B 156 3725 21084 63176 1005107 B ATOM 4740 CG2 VAL B 145 7124 -0104 42181 1004335 B ATOM 4825 CG LYS B 156 2951 22338 63563 1005326 B ATOM 4741 C VAL B 145 3789 1669 41556 1004728 B ATOM 4826 CD LYS B 156 2344 22267 64966 1005326 B ATOM 4742 O VAL B 145 3581 2367 42546 1004996 B ATOM 4827 CE LYS B 156 3395 22303 66081 1005326 B ATOM 4743 N TYR B 146 2832 1332 40697 1004865 B ATOM 4828 NZ LYS B 156 2782 22405 67441 1005326 B ATOM 4744 CA TYR B 146 1461 1 787 40884 1004686 B ATOM 4829 C LYS B 156 5291 22338 61706 1004091 B ATOM 4745 CB TYR B 146 1242 3 165 40226 1003871 B ATOM 4830 O LYS B 156 6402 22266 62226 1004091 B ATOM 4746 CG TYR B 146 1737 3259 38799 1003874 B ATOM 4831 N TYR B 157 4850 23417 61062 1003957 B ATOM 4747 CDl TYR B 146 3067 3564 38522 1003813 B ATOM 4832 CA TYR B 157 5625 24650 60934 1003957 B ATOM 4748 CEl TYR B 146 3539 3618 37220 1003692 B ATOM 4833 CB TYR B 157 5747 25076 59468 1004766 B ATOM 4749 CD2 TYR B 146 0888 3010 37734 1003433 B ATOM 4834 CG TYR B 157 6736 24272 58654 1003000 B ATOM 4750 CE2 TYR B 146 1346 3059 36420 1003638 B ATOM 4835 CDl TYR B 157 7370 23158 59188 1003000 B ATOM 4751 CZ TYR B 146 2673 3363 36168 1003642 B ATOM 4836 CEl TYR B 157 8263 22415 58431 1003000 B ATOM 4752 OH TYR B 146 3128 3400 34871 1003740 B ATOM 4837 CD2 TYR B 157 7028 24621 57328 1003000 B ATOM 4753 C TYR B 146 0440 0793 40354 1004517 B ATOM 4838 CE2 TYR B 157 7927 23878 56562 1003000 B ATOM 4754 O TYR B 146 0763 -0127 39599 1004334 B ATOM 4839 CZ TYR B 157 8537 22782 57124 1003000 B ATOM 4755 N PHE B 147 -0806 1011 40752 1003622 B ATOM 4840 OH TYR B 157 9433 22051 56376 1003000 B ATOM 4756 CA PHE B 147 1910 0144 40387 1003574 B ATOM 4841 C TYR B 157 4880 25733 61719 1003957 B ATOM 4757 CB PHE B 147 -1966 -0987 41418 1003766 B ATOM 4842 O TYR B 157 3677 25930 61531 1003957 B ATOM 4758 CG PHE B 147 -3190 -1 850 41347 1003671 B ATOM 4843 N ASN B 158 5594 26433 62594 1004067 B ATOM 4759 CDl PHE B 147 -3770 -2182 40131 1003720 B ATOM 4844 CA ASN B 158 4993 27480 63417 1004067 B ATOM 4760 CD2 PHE B 147 -3719 -2407 42518 1003904 B ATOM 4845 CB ASN B 158 4948 27002 64880 1002681 B ATOM 4761 CEl PHE B 147 -4856 -3061 40083 1003753 B ATOM 4846 CG ASN B 158 4308 28004 65832 1003751 B ATOM 4762 CE2 PHE B 147 -4801 -3285 42479 1003761 B ATOM 4847 ODl ASN B 158 3932 29114 65449 1003751 B ATOM 4763 CZ PHE B 147 -5369 -3615 41267 1003845 B ATOM 4848 ND2 ASN B 158 4192 27594 67092 1003751 B ATOM 4764 C PHE B 147 -3150 1028 40432 1003728 B ATOM 4849 C ASN B 158 5796 28774 63315 1004067 B ATOM 4765 O PHE B 147 -3373 1 740 41407 1003476 B ATOM 4850 O ASN B 158 6955 28837 63749 1004067 B ATOM 4766 N GLY B 148 -3942 1010 39365 I 003029 B ATOM 4851 N TYR B 159 5192 29797 62717 1003183 B ATOM 4767 CA GLY B 148 -5127 1842 39351 1003477 B ATOM 4852 CA TYR B 159 5846 31 100 62616 1003183 B ATOM 4768 C GLY B 148 -6219 1364 38423 1003699 B ATOM 4853 CB TYR B 159 5708 31700 61220 1003153 B ATOM 4769 O GLY B 148 -6010 0462 37605 1003960 B ATOM 4854 CG TYR B 159 6373 30929 60115 1003509 B ATOM 4770 N ILE B 149 -7393 1970 38565 1003551 B ATOM 4855 CDl TYR B 159 5741 29841 59526 1003509 B ATOM 4771 CA ILE B 149 -8543 1649 37733 1003392 B ATOM 4856 CEl TYR B 159 6301 29187 58444 1003509 B ATOM 4772 CB ILE B 149 -9384 0483 38307 1004517 B ATOM 4857 CD2 TYR B 159 7600 31337 59597 1003509 B ATOM 4773 CG2 ILE B 149 -8500 -0693 38651 1004572 B ATOM 4858 CE2 TYR B 159 8171 30687 58515 1003509 B ATOM 4774 CGl ILE B 149 -10093 0915 39575 1004121 B ATOM 4859 CZ TYR B 159 7510 29614 57941 1003509 B ATOM 4775 CDl ILE B 149 -11056 -0132 40036 1004446 B ATOM 4860 OH TYR B 159 8048 28987 56837 1003509 B ATOM 4776 C ILE B 149 -9429 2874 37638 1003596 B ATOM 4861 C TYR B 159 5144 32030 63586 1003183 B ATOM 4777 O ILE B 149 -9509 3683 38564 10041 13 B ATOM 4862 O TYR B 159 3914 32146 63538 1003183 B ATOM 4778 N ILE B 150 -10097 3000 36509 1003481 B ATOM 4863 N THR B 160 5901 32706 64448 1004356 B ATOM 4779 CA ILE B 150 -10984 4126 36273 1003532 B ATOM 4864 CA THR B 160 5267 33609 65403 1004356 B ATOM 4780 CB ILE B 150 -10257 5209 35407 1003461 B ATOM 4865 CB THR B 160 5096 32916 66771 1005225 B ATOM 4781 CG2 ILE B 150 -9717 4594 34139 1003791 B ATOM 4866 OGl THR B 160 4406 31668 66605 1003959 B ATOM 4782 CGl ILE B 150 -11212 6339 35060 1003260 B ATOM 4867 CG2 THR B 160 4309 33793 67701 1003959 B ATOM 4783 CDl ILE B 150 -11575 7211 36241 1003061 B ATOM 4868 C THR B 160 5971 34947 65645 1004356 B ATOM 4784 C ILE B 150 -12213 3567 35546 1003666 B ATOM 4869 O THR B 160 7176 34976 65947 1004356 B ATOM 4785 O ILE B 150 -12097 2737 34652 1003577 B ATOM 4870 N VAL B 161 5239 36055 65484 1004279 B ATOM 4786 N ALA B 151 -13393 4006 35950 1005571 B ATOM 4871 CA VAL B 161 5812 37372 65798 1004279 B ATOM 4787 CA ALA B 151 -14618 3537 35325 1005445 B ATOM 4872 CB VAL B 161 5712 38382 64646 1005667 B ATOM 4788 CB ALA B 151 -15781 3732 36280 1001771 B ATOM 4873 CGl VAL B 161 6238 37765 63378 10041 18 B ATOM 4789 C ALA B 151 -14868 4303 34030 1005541 B ATOM 4874 CG2 VAL B 161 4309 38841 64481 10041 18 B ATOM 4790 O ALA B 151 -14947 5528 34029 1005779 B ATOM 4875 C VAL B 161 5031 37892 67009 1004279 B ATOM 4791 N LEU B 152 14992 3579 32929 1006710 B ATOM 4876 O VAL B 161 3805 37768 67072 1004279 B 65251/C766

ATOM 4877 N THR B 162 5 747 38 447 67 979 1 0049 90 B ATOM 4962 CB PHE B 173 10499 29883 62407 1005331 B ATOM 4878 CA THR B 162 5 121 38 941 69 199 1 0049 90 B ATOM 4963 CG PHE B 173 10262 28703 61538 10035 13 B ATOM 4879 CB THR B 162 5 582 38 112 70416 1 00 83 68 B ATOM 4964 CDl PHE B 173 9015 28498 60965 1003513 B ATOM 4880 OGl THR B 162 5 743 36 748 70 026 1 0055 01 B ATOM 4965 CD2 PHE B 173 11260 27747 61364 1003513 B ATOM 4881 CG2 THR B 162 4 559 38 167 71 522 1 00 55 01 B ATOM 4966 CEl PHE B 173 8757 27359 60237 1003513 B ATOM 4882 C THR B 162 5 495 40 389 69453 1 0049 90 B ATOM 4967 CE2 PHE B 173 11 017 26606 60641 1003513 B ATOM 4883 O THR B 162 6580 40 829 69061 1 004990 B ATOM 4968 CZ PHE B 173 9755 26404 60072 1003513 B ATOM 4884 N LEU B 163 4 606 41 133 70 110 1 00 71 09 B ATOM 4969 C PHE B 173 10345 28353 64345 1003769 B ATOM 4885 CA LEU B 163 4 894 42 524 70 423 1 00 71 09 B ATOM 4970 O PHE B 173 11486 28169 64762 1003769 B ATOM 4886 CB LEU B 163 3 614 43 301 70 681 1 00109 26 B ATOM 4971 N TYR B 174 9418 27403 64347 1003735 B ATOM 4887 CG LEU B 163 3482 44 542 69 802 1 00 57 35 B ATOM 4972 CA TYR B 174 9721 26066 64812 1003735 B ATOM 4888 CDl LEU B 163 2 302 45 352 70287 1 00 57 35 B ATOM 4973 CB TYR B 174 8997 25751 66110 1005709 B ATOM 4889 CD2 LEU B 163 4 741 45 389 69 842 1 00 57 35 B ATOM 4974 CG TYR B 174 9461 26552 67281 1004313 B ATOM 4890 C LEU B 163 5 787 42 587 71 656 1 00 71 09 B ATOM 4975 CDl TYR B 174 8679 27592 67787 1004313 B ATOM 4891 O LEU B 163 6 298 43 648 72 029 1 00 71 09 B ATOM 4976 CEl TYR B 174 9096 28335 68898 10043 13 B ATOM 4892 N LYS B 164 5 994 41 436 72281 1 00178 73 B ATOM 4977 CD2 TYR B 174 10676 26271 67906 1004313 B ATOM 4893 CA LYS B 164 6 829 41 384 73 467 1 00178 73 B ATOM 4978 CE2 TYR B 174 11 102 27006 69014 1004313 B ATOM 4894 CB LYS B 164 8 303 41 538 73 079 1 00 52 39 B ATOM 4979 CZ TYR B 174 10307 28034 69504 1004313 B ATOM 4895 CG LYS B 164 9063 40 225 73 097 1 00 52 14 B ATOM 4980 OH TYR B 174 10709 28763 70599 1004313 B ATOM 4896 CD LYS B 164 9038 39 593 74 485 1 00 52 14 B ATOM 4981 C TYR B 174 9281 25062 63774 1003735 B ATOM 4897 CE LYS B 164 9 827 38 285 74 552 1 00 52 14 B ATOM 4982 O TYR B 174 8194 25191 63213 1003735 B ATOM 4898 NZ LYS B 164 9961 37 758 75 971 1 00 52 14 B ATOM 4983 N ASP B 175 10134 24059 63542 1004175 B ATOM 4899 C LYS B 164 6 411 42 510 74396 1 00178 73 B ATOM 4984 CA ASP B 175 9889 22965 62600 1004175 B ATOM 4900 O LYS B 164 5 313 43 050 74257 1 00178 73 B ATOM 4985 CB ASP B 175 11046 22863 61604 1005686 B ATOM 4901 N ASP B 165 7 271 42 861 75 348 1 0014949 B ATOM 4986 CG ASP B 175 10810 21823 60533 1004507 B ATOM 4902 CA ASP B 165 6954 43 945 76 263 1 00149 49 B ATOM 4987 ODl ASP B 175 10140 20809 60825 1004507 B ATOM 4903 CB ASP B 165 8053 44 100 77 322 1 00163 18 B ATOM 4988 OD2 ASP B 175 11309 22008 59403 1004507 B ATOM 4904 CG ASP B 165 9447 44 130 76 721 1 00163 18 B ATOM 4989 C ASP B 175 9843 21711 63468 1004175 B ATOM 4905 ODl ASP B 165 9 754 45 082 75 966 1 00163 18 B ATOM 4990 O ASP B 175 10846 21324 64070 1004175 B ATOM 4906 OD2 ASP B 165 10 232 43 195 77007 1 00163 18 B ATOM 4991 N HIS B 176 8681 21082 63551 1004280 B ATOM 4907 C ASP B 165 6 831 45 204 75 417 1 00149 49 B ATOM 4992 CA HIS B 176 8538 19879 64368 1004280 B ATOM 4908 O ASP B 165 6 187 45 192 74 363 1 0014949 B ATOM 4993 CB HIS B 176 7508 20105 65471 1008422 B ATOM 4909 N ASP B 166 7453 46291 75 851 1 00 65 56 B ATOM 4994 CG HIS B 176 7997 20939 66611 1005335 B ATOM 4910 CA ASP B 166 7352 47 509 75 067 1 00 65 56 B ATOM 4995 CD2 HIS B 176 7667 22193 67003 1005335 B ATOM 491 1 CB ASP B 166 7243 48 725 75 993 1 00200 84 B ATOM 4996 NDl HIS B 176 8902 20475 67539 1005335 B ATOM 4912 CG ASP B 166 5 959 48 719 76 808 1 00200 84 B ATOM 4997 CEl HIS B 176 9105 21404 68457 I 005335 B ATOM 4913 ODl ASP B 166 5 754 47766 77 590 1 00200 84 B ATOM 4998 NE2 HIS B 176 8366 22455 68155 1005335 B ATOM 4914 OD2 ASP B 166 5 155 49665 76664 1 0020084 B ATOM 4999 C HIS B 176 8094 18664 63562 1004280 B ATOM 4915 C ASP B 166 8484 47 693 74 052 1 00 65 56 B ATOM 5000 O HIS B 176 7097 18715 62838 1004280 B ATOM 4916 O ASP B 166 9 664 47727 74407 1 00 65 56 B ATOM 5001 N TYR B 177 8849 17577 63679 1004241 B ATOM 4917 N GLY B 167 8 104 47 770 72 777 1 00 60 37 B ATOM 5002 CA TYR B 177 8494 16322 63024 1004241 B ATOM 4918 CA GLY B 167 9086 47 979 71 744 1 00 60 37 B ATOM 5003 CB TYR B 177 9713 15650 62410 1005484 B ATOM 4919 C GLY B 167 8 958 47240 70424 1 00 60 37 B ATOM 5004 CG TYR B 177 9357 14311 61 841 1004785 B ATOM 4920 O GLY B 167 7 989 47 380 69 660 1 0060 37 B ATOM 5005 CDl TYR B 177 8525 14213 60724 1004785 B ATOM 4921 N LEU B 168 9 996 46455 70 167 1 0049 81 B ATOM 5006 CEl TYR B 177 8143 12978 60211 I 004785 B ATOM 4922 CA LEU B 168 10 144 45 680 68955 1 0049 81 B ATOM 5007 CD2 TYR B 177 9804 13135 62437 1004785 B ATOM 4923 CB LEU B 168 11 603 45 223 68 873 1 00 51 56 B ATOM 5008 CE2 TYR B 177 9430 11897 61936 1004785 B ATOM 4924 CG LEU B 168 12 576 46206 69 551 1 00 51 56 B ATOM 5009 CZ TYR B 177 8597 U 824 60821 1004785 B ATOM 4925 CDl LEU B 168 13 979 45 635 69 559 1 00 51 56 B ATOM 5010 OH TYR B 177 8207 10604 60309 1004785 B ATOM 4926 CD2 LEU B 168 12 547 47 541 68 839 1 0051 56 B ATOM 5011 C TYR B 177 8003 15501 64206 1004241 B ATOM 4927 C LEU B 168 9 207 44478 68 856 1 00 49 81 B ATOM 5012 O TYR B 177 8782 15191 65090 1004241 B ATOM 4928 O LEU B 168 8 479 44 137 69 792 1 0049 81 B ATOM 5013 N ASN B 178 6725 15146 64236 1004024 B ATOM 4929 N TYR B 169 9 222 43 851 67688 1 00 32 54 B ATOM 5014 CA ASN B 178 6191 14425 65394 1004024 B ATOM 4930 CA TYR B 169 8430 42 657 67442 1 003254 B ATOM 5015 CB ASN B 178 6925 13102 65658 1005550 B ATOM 4931 CB TYR B 169 7649 42 775 66 138 1 00 57 17 B ATOM 5016 CG ASN B 178 6533 12001 64679 1004797 B ATOM 4932 CG TYR B 169 6 543 43 799 66 160 1 00 57 17 B ATOM 5017 ODl ASN B 178 5572 12137 63920 1004797 B ATOM 4933 CDl TYR B 169 6 820 45 167 66 052 1 00 57 17 B ATOM 5018 ND2 ASN B 17S 7271 10897 64705 1004797 B ATOM 4934 CEl TYR B 169 5 798 46 108 66 072 1 00 57 17 B ATOM 5019 C ASN B 178 6464 15387 66540 1004024 B ATOM 4935 CD2 TYR B 169 5 214 43 403 66289 1 00 S ^-7 17 B ATOM 5020 O ASN B 178 6244 16583 66395 1004024 B ATOM 4936 CE2 TYR B 169 4 188 44 333 66 310 1 00 57 17 B ATOM 5021 N ASP B 179 6952 14889 67667 1004189 B ATOM 4937 CZ TYR B 169 4487 45 681 66 201 1 00 57 17 B ATOM 5022 CA ASP B 179 7245 15785 68780 10041 89 B ATOM 4938 OH TYR B 169 3468 46600 66224 1 00 57 17 B ATOM 5023 CB ASP B 179 6839 15146 70125 1004210 B ATOM 4939 C TYR B 169 9 400 41 484 67 321 1 00 32 54 B ATOM 5024 CG ASP B 179 7472 13782 70356 1004605 B ATOM 4940 O TYR B 169 10 307 41 503 66484 1 00 32 54 B ATOM 5025 ODl ASP B 179 8253 13323 69493 1004605 B ATOM 4941 N ASP B 170 9224 40476 68 168 1 00 46 78 B ATOM 5026 OD2 ASP B 179 7182 13165 71410 1004605 B ATOM 4942 CA ASP B 170 10082 39 314 68 105 1 00 4678 B ATOM 5027 C ASP B 179 8720 16183 68804 1004189 B ATOM 4943 CB ASP B 170 10209 38 651 69 480 1 00 72 79 B ATOM 5028 O ASP B 179 9195 16733 69787 1004189 B ATOM 4944 CG ASP B 170 11 411 39 155 70 249 1 00 72 79 B ATOM 5029 N GLN B 180 9430 15921 67710 1003851 B ATOM 4945 ODl ASP B 170 12 442 39415 69 597 1 0072 79 B ATOM 5030 CA GLN B 180 10855 16231 67603 1003851 B ATOM 4946 OD2 ASP B 170 11 340 39277 71 489 1 0072 79 B ATOM 5031 CB GLN B 180 11562 15167 66768 1005873 B ATOM 4947 C ASP B 170 9 523 38 330 67 100 1 00 46 78 B ATOM 5032 CG GLN B 180 11363 13762 67242 1005036 B ATOM 4948 O ASP B 170 8331 38 325 66 820 1 00 46 78 B ATOM 5033 CD GLN B 180 11835 13575 68656 1005036 B ATOM 4949 N GLY B 171 10 393 37 509 66 535 1 0036 17 B ATOM 5034 OEl GLN B 180 11035 13555 69592 1005036 B ATOM 4950 CA GLY B 171 9939 36 510 65 589 1 00 36 17 B ATOM 5035 NE2 GLN B 180 13150 13452 68827 1005036 B ATOM 4951 C GLY B 171 10 642 35 182 65 813 1 0036 17 B ATOM 5036 C GLN B 180 11 169 17588 66973 1003851 B ATOM 4952 O GLY B 171 11 855 35 147 66022 1 0036 17 B ATOM 5037 O GLN B 180 10811 17838 65822 1003851 B ATOM 4953 N VAL B 172 9 869 34 099 65 807 1 00 39 26 B ATOM 5038 N LEU B 181 11852 18457 67714 1003788 B ATOM 4954 CA VAL B 172 10416 32 765 65 950 1 00 39 26 B ATOM 5039 CA LEU B 181 12234 19755 67181 1003788 B ATOM 4955 CB VAL B 172 10215 32 151 67 355 1 00 32 02 B ATOM 5040 CB LEU B 181 12824 20632 68278 1004598 B ATOM 4956 CGl VAL B 172 11 316 32 557 68253 1 002403 B ATOM 5041 CG LEU B 181 13354 21962 67755 1003341 B ATOM 4957 CG2 VAL B 172 8 854 32 531 67 909 1 00 24 03 B ATOM 5042 CDl LEU B 181 12236 22771 67113 1003341 B ATOM 4958 C VAL B 172 9 730 31 828 64 984 1 00 39 26 B ATOM 5043 CD2 LEU B 181 14003 22732 68889 1003341 B ATOM 4959 O VAL B 172 8 595 32 060 64 553 1 00 39 26 B ATOM 5044 C LEU B 181 13277 19516 66087 1003788 B ATOM 4960 N PHE B 173 10427 30 742 64 677 1 00 37 69 B ATOM 5045 O LEU B 181 14245 18788 66285 1003788 B ATOM 4961 CA PHE B 173 9923 29 715 63 798 1 003769 B ATOM 5046 N VALB 182 13073 20118 64924 1004021 B 65251/C766

ATOM 5047 CA VAL B 182 13999 19945 63823 1004021 B ATOM 5132 CG ARG B 192 17883 45007 61 117 1008790 B ATOM 5048 CB VAL B 182 13253 19562 62543 1004695 B ATOM 5133 CD ARG B 192 16690 45071 62054 1008790 B ATOM 5049 CGl VALB 182 14234 19445 61389 1002543 B ATOM 5134 NE ARG B 192 16836 46105 63077 1008790 B ATOM 5050 CG2 VALB182 12503 18269 62752 1002543 B ATOM 5135 CZ ARGB 192 16893 47408 62824 1008790 B ATOM 5051 C VAL B 182 14771 21227 63560 1004021 B ATOM 5136 NHl ARG B 192 16814 47842 61573 1008790 B ATOM 5052 O VALB 182 15975 21199 63283 1004021 B ATOM 5137 NH2ARGB192 17026 48275 63822 1008790 B ATOM 5053 N THR B 183 14071 22353 63644 1004006 B ATOM 5138 C ARG B 192 17273 41349 60070 1005903 B ATOM 5054 CA THRB 183 14687 23643 63389 1004006 B ATOM 5139 O ARG B 192 16642 41596 59045 1005903 B ATOM 5055 CB THR B 183 14549 24042 61903 1005668 B ATOM 5140 N HIS B 193 17624 40115 60419 1004720 B ATOM 5056 OGl THR B 183 15291 23132 61086 1004327 B ATOM 5141 CA HIS B 193 17236 38951 59633 1004720 B ATOM 5057 CG2THRB183 1505025460 61681 1004327 B ATOM 5142 CB HIS B 193 18179 38768 58443 1006835 B ATOM 5058 C THR B 183 14065 24763 64194 I 004006 B ATOM 5143 CG HIS B 193 19540 38268 58806 1006835 B ATOM 5059 O THR B 183 1284924795 64376 1004006 B ATOM 5144 CD2HISB 193 20000 37629 59905 1006835 B ATOM 5060 N LYS B 184 1490625667 64690 1003810 B ATOM 5145 NDl HISB 193 20605 38346 57939 1006835 B ATOM 5061 CA LYSB 184 14423 26834 65402 1003810 B ATOM 5146 CEl HIS B 193 21663 37774 58485 1006835 B ATOM 5062 CB LYSB 184 14765 26810 66874 1004237 B ATOM 5147 NE2 HIS B 193 21322 37331 59679 1006835 B ATOM 5063 CG LYS B 184 1430628088 67553 1003421 B ATOM 5148 C HIS B 193 17239 37737 60570 1004720 B ATOM 5064 CD LYS B 184 14651 28133 69028 1003421 B ATOM 5149 O HIS B 193 17708 37834 61704 1004720 B ATOM 5065 CE LYS B 184 1419429447 69654 1003421 B ATOM 5150 N GLY B 194 16715 36603 60120 1004906 B ATOM 5066 NZ LYS B 184 1465929592 71064 1003421 B ATOM 5151 CA GLYB 194 16657 35443 60996 1004906 B ATOM 5067 C LYS B 184 15113 28027 64772 1003810 B ATOM 5152 C GLY B 194 17948 34673 61 135 1004906 B ATOM 5068 O LYS B 184 16331 28007 64526 1003810 B ATOM 5153 O GLY B 194 18846 34830 60320 1004906 B ATOM 5069 N ILEB 185 1432729057 64479 1004204 B ATOM 5154 N ASN B 195 18044 33849 62178 1004565 B ATOM 5070 CA ILE B 185 1485430268 63878 1004204 B ATOM 5155 CA ASNB 195 19231 33023 62426 1004565 B ATOM 5071 CB ILE B 185 14487 30353 62383 1005632 B ATOM 5156 CB ASN B 195 20112 33587 63545 1005759 B ATOM 5072 CG2ILEB185 1480831710 61840 1002524 B ATOM 5157 CG ASN B 195 20809 34856 63159 1005759 B ATOM 5073 CGl ILEB 185 1529429333 61595 1002524 B ATOM 5158 ODlASN B 195 21341 34983 62055 1005759 B ATOM 5074 CDl ILE B 185 14871 29222 60142 1002524 B ATOM 5159 ND2ASNB195 20832 35804 64076 1005759 B ATOM 5075 C ILE B 185 1426731452 64614 1004204 B ATOM 5160 C ASNB 195 18762 31660 62880 1004565 B ATOM 5076 O ILE B 185 13098 31441 64990 1004204 B ATOM 5161 O ASN B 195 17801 31565 63651 1004565 B ATOM 5077 N SER B 186 15087 32466 64859 1004552 B ATOM 5162 N VAL B 196 19430 30606 62413 1003921 B ATOM 5078 CA SERB 186 1459733660 65531 1004552 B ATOM 5163 CA VALB 196 19052 29270 62836 1003921 B ATOM 5079 CB SERB 186 1494033637 67017 1007285 B ATOM 5164 CB VALB 196 19555 28199 61875 1003411 B ATOM 5080 OG SERB 186 1627233250 67218 1006196 B ATOM 5165 CGl VAL B 196 19177 26817 62405 1003411 B ATOM 5081 C SERB 186 15141 34910 64865 1004552 B ATOM 5166 CG2 VALB196 18952 28419 60510 1003411 B ATOM 5082 O SER B 186 16218 34885 64254 1004552 B ATOM 5167 C VALB 196 19699 29050 64185 1003921 B ATOM 5083 N TYRB 187 1436735991 64959 1003643 B ATOM 5168 O VAL B 196 20918 29077 64291 1003921 B ATOM 5084 CA TYRB 187 14733 37248 64345 1003643 B ATOM 5169 N ASNB 197 18884 28848 65213 1005518 B ATOM 5085 CB TYR B 187 13509 38136 64210 1007763 B ATOM 5170 CA ASN B 197 19406 28634 66554 1005518 B ATOM 5086 CG TYR B 187 13789 39401 63447 1003184 B ATOM 5171 CB ASN B 197 18457 29202 67612 1006215 B ATOM 5087 CDl TYRB 187 14011 39374 62073 1003184 B ATOM 5172 CG ASN B 197 17999 30592 67294 1006215 B ATOM 5088 CEl TYR B 187 14269 40537 61364 1003184 B ATOM 5173 ODl ASN B 197 18801 31457 66960 1006215 B ATOM 5089 CD2TYRB187 13841 40630 64096 1003184 B ATOM 5174 ND2ASNB197 16697 30822 67404 1006215 B ATOM 5090 CE2TYRB187 14106 41806 63400 1003184 B ATOM 5175 C ASNB 197 19580 27152 66830 1005518 B ATOM 5091 CZ TYRB 187 1431941754 62038 1003184 B ATOM 5176 O ASN B 197 20469 26753 67579 1005518 B ATOM 5092 OH TYR B 187 14613 42908 61354 1003184 B ATOM 5177 N PHEB 198 18726 26336 66228 1003544 B ATOM 5093 C TYR B 187 15799 37966 65154 1003643 B ATOM 5178 CA PHE B 198 18776 24907 66452 1003544 B ATOM 5094 O TYR B 187 15601 38276 66323 1003643 B ATOM 5179 CB PHE B 198 17722 24522 67490 1003311 B ATOM 5095 N ASN B 188 16935 38221 64514 1003749 B ATOM 5180 CG PHE B 198 17714 23074 67828 1003311 B ATOM 5096 CA ASN B 188 1804738915 65135 1003749 B ATOM 5181 CDl PHEB 198 18484 22589 68875 10033 U B ATOM 5097 CB ASN B 188 19342 38494 64452 10017891 B ATOM 5182 CD2PHEB 198 16994 22175 67051 10033 Il B ATOM 5098 CG ASNB 188 2054439134 65076 1003994 B ATOM 5183 CEl PHEB 198 18548 21216 69145 1003311 B ATOM 5099 ODl ASN B 188 2060740343 65217 1003994 B ATOM 5184 CE2PHEB198 17048 20801 67310 1003311 B ATOM 5100 ND2ASNB188 21509 38331 65452 1003994 B ATOM 5185 CZ PHE B 198 17831 20321 68361 1003311 B ATOM 5101 C ASN B 188 1783940427 64953 1003749 B ATOM 5186 C PHE B 198 18530 24110 65186 1003544 B ATOM 5102 O ASN B 188 17920 40946 63835 1003749 B ATOM 5187 O PHEB 198 17748 24506 64325 1003544 B ATOM 5103 N HIS B 189 1757441140 66042 1003602 B ATOM 5188 N ARGB 199 19203 22979 65079 1005429 B ATOM 5104 CA HIS B 189 17363 42589 65965 1003602 B ATOM 5189 CA ARG B 199 19027 22105 63939 1005429 B ATOM 5105 CB HISB 189 16811 43083 67279 1008704 B ATOM 5190 CB ARG B 199 19997 22443 62819 1005430 B ATOM 5106 CG HIS B 189 1539742675 67496 1004758 B ATOM 5191 CG ARG B 199 1984021495 61658 1005430 B ATOM 5107 CD2HISB189 1486641642 68189 1004758 B ATOM 5192 CD ARG B 199 18590 21815 60864 1005430 B ATOM 5108 NDl HIS B 189 1433743309 66885 1004758 B ATOM 5193 NE ARG B 199 18933 22633 59706 1005430 B ATOM 5109 CEl HIS B 189 1321342682 67194 1004758 B ATOM 5194 CZ ARG B 199 18183 23618 59232 1005430 B ATOM 5110 NE2HISB1S9 1350641665 67984 1004758 B ATOM 5195 NHl ARG B 199 17042 23919 59814 1005430 B ATOM 5111 C HIS B 189 1858443424 65570 1003602 B ATOM 5196 NH2ARGB 199 18578 24307 58174 1005430 B ATOM 5112 O HIS B 189 1843744496 64998 1003602 B ATOM 5197 C ARGB 199 19291 20687 64404 1005429 B ATOM 5113 N GLU B 190 1978442928 65866 1004432 B ATOM 5198 O ARGB 199 20391 20369 64852 1005429 B ATOM 5114 CA GLU B 190 21013 43626 65526 1004432 B ATOM 5199 N ALA B 200 18285 19831 64309 1004153 B ATOM 5115 CB GLU B 190 2218242954 66229 10010431 3 ATOM 5200 CA ALA B 200 18448 18447 64730 1004153 B ATOM 5116 CG GLUB 190 23395 43821 66441 1007873 B ATOM 5201 CB ALA B 200 17162 17681 64493 1004485 B ATOM 5117 CD GLU B 190 2447043096 67245 1007873 B ATOM 5202 C ALA B 200 19605 17786 63983 1004153 B ATOM 5118 OEl GLUB 190 25016 42091 66742 1007873 B ATOM 5203 O ALA B 200 19748 17941 62769 1004153 B ATOM 5119 OE2GLUB190 24764 43517 68384 1007873 B ATOM 5204 N ASP B 201 20426 17045 64718 1005831 B ATOM 5120 C GLUB 190 2118543537 64010 1004432 B ATOM 5205 CA ASP B 201 21585 16369 64149 1005831 B ATOM 5121 O GLU B 190 21304 44556 63325 1004432 B ATOM 5206 CB ASP B 201 22345 15657 65258 10013434 B ATOM 5122 N THRB 191 2116642307 63494 1003782 B ATOM 5207 CG ASP B 201 21433 14820 66121 10013434 B ATOM 5123 CA THR B 191 2133442033 62074 1003782 B ATOM 5208 ODl ASP B 201 20592 15412 66836 10013434 B ATOM 5124 CB THR B 191 2170540576 61870 1005657 B ATOM 5209 OD2 ASP B 201 21546 13575 66073 10013434 B ATOM 5125 OGl THR B 191 22949 40326 62522 1005657 B ATOM 5210 C ASP B 201 21244 15363 63053 1005831 B ATOM 5126 CG2THRB 191 2183940262 60387 1005657 B ATOM 5211 O ASP B 201 22054 15120 62157 1005831 B ATOM 5127 C THRB 191 201324234061192 1003782 B ATOM 5212 N TRP B 202 20054 14775 63115 1006417 B ATOM 5128 O THRB 191 2030042652 60025 1003782 B ATOM 5213 CA TRP B 202 19656 13778 62123 1006417 B ATOM 5129 N ARG B 192 18929 42219 61744 1005903 B ATOM 5214 CB TRP B 202 18683 12776 62733 1004254 B ATOM 5130 CA ARG B 192 1769442476 61008 1005903 B ATOM 5215 CG TRP B 202 17481 13384 63378 1004254 B ATOM 5131 CB ARG B 192 17793 43790 60231 1008790 B ATOM 5216 CD2TRPB202 16229 13696 62748 1004254 B 65251/C766

ATOM 5217 CE2 TRP B 202 15372 14209 63751 1004254 B ATOM 5302 CA PRO B 212 11253 25646 52001 1004060 B ATOM 5218 CE3 TRP B 202 15746 13589 61436 1004254 B ATOM 5303 CB PRO B 212 10249 26474 52786 1004199 B ATOM 5219 CDl TRP B 202 17337 13718 64696 1004254 B ATOM 5304 CG PRO B 212 9135 25491 53018 1004199 B ATOM 5220 NEl TRP B 202 16072 14211 64929 1004254 B ATOM 5305 C PRO B 212 12683 26185 52135 1004060 B ATOM 5221 CZ2 TRP B 202 14060 14612 63480 1004254 B ATOM 5306 O PRO B 212 1334725954 53142 1004060 B ATOM 5222 CZ3 TRP B 202 14442 13989 61169 1004254 B ATOM 5307 N GLY B 213 13151 26907 51 119 1004588 B ATOM 5223 CH2 TRP B 202 13616 14494 62189 1004254 B ATOM 5308 CA GLY B 213 14492 27469 51153 1004588 B ATOM 5224 C TRP B 202 19037 14302 60837 1006417 B ATOM 5309 C GLY B 213 14535 28813 51849 1004588 B ATOM 5225 O TRP B 202 18819 13526 59901 1006417 B ATOM 5310 O GLY B 213 1350229298 52310 1004588 B ATOM 5226 N PHE B 203 18764 15604 60782 1004765 B ATOM 5311 N ASN B 214 15715 29428 51917 1005630 B ATOM 5227 CA PHE B 203 18136 16200 59614 1004765 B ATOM 5312 CA ASN B 214 15903 30720 52591 1005630 B ATOM 5228 CB PHE B 203 17072 17193 60078 1003915 B ATOM 5313 CB ASN B 214 15076 31827 51952 1008278 B ATOM 5229 CG PHE B 203 16210 17724 58971 1003915 B ATOM 5314 CG ASN B 214 15023 31722 50466 1007695 B ATOM 5230 CDl PHE B 203 15297 1689658324 1003915 B ATOM 5315 ODl ASN B 214 15838 31044 49853 1007695 B ATOM 5231 CD2 PHE B 203 16303 1905458573 1003915 B ATOM 5316 ND2 ASN B 214 14059 32406 49864 1007695 B ATOM 5232 CEl PHE B 203 14484 1739457290 1003915 B ATOM 5317 C ASN B 214 15434 30566 54019 1005630 B ATOM 5233 CE2 PHE B 203 15504 19555 57552 1003915 B ATOM 5318 O ASN B 214 14613 31352 54497 1005630 B ATOM 5234 CZ PHE B 203 14594 18729 56910 1003915 B ATOM 5319 N ASP B 215 1594629549 54701 1003970 B ATOM 5235 C PHE B 203 19116 16897 58689 1004765 B ATOM 5320 CA ASP B 215 1555029289 56074 1003970 B ATOM 5236 O PHE B 203 19641 17955 59032 1004765 B ATOM 5321 CB ASP B 215 16249 30253 57010 10015111 B ATOM 5237 N ASN B 204 19376 16293 57528 1005031 B ATOM 5322 CG ASP B 215 1773830206 56852 1007249 B ATOM 5238 CA ASN B 204 20258 16895 56531 1005031 B ATOM 5323 ODl ASP B 215 183182910756994 1007249 B ATOM 5239 CB ASN B 204 21065 15834 55758 1009015 B ATOM 5324 OD2 ASP B 215 18333 31266 56578 1007249 B ATOM 5240 CG ASN B 204 21770 16409 54528 1009015 B ATOM 5325 C ASP B 215 1404629425 56198 1003970 B ATOM 5241 ODl ASN B 204 21116 16891 53611 1009015 B ATOM 5326 O ASP B 215 13557 30311 56889 1003970 B ATOM 5242 ND2 ASN B 204 23096 16363 54495 1009015 B ATOM 5327 N TYR B 216 13330 28557 55488 1003261 B ATOM 5243 C ASN B 204 19295 17617 55598 1005031 B ATOM 5328 CA TYR B 216 11882 28521 555(5 1003261 B ATOM 5244 O ASN B 204 18685 16995 54736 1005031 B ATOM 5329 CB TYR B 216 113902802956881 1005670 B ATOM 5245 N ILE B 205 19152 18928 55780 1005735 B ATOM 5330 CG TYR B 216 1201726722 57322 1003545 B ATOM 5246 CA ILE B 205 18227 19707 54969 1005735 B ATOM 5331 CD1 TYR B 216 13366 26657 57655 1003545 B ATOM 5247 CB ILE B 205 18246 21200 55377 1005624 B ATOM 5332 CEl TYR B 216 13943 25478 58061 1003545 B ATOM 5248 CG2 ILE B 205 19411 21914 54735 1005624 B ATOM 5333 CD2 TYR B 216 1125825551 57412 1003545 B ATOM 5249 CGl ILE B 205 1693621864 54954 I 005624 B ATOM 5334 CE2 TYR B 216 11831 24363 57826 1003545 B ATOM 5250 CDl ILE B 205 1665723158 55685 1005624 B ATOM 5335 CZ TYR B 216 13175 24338 58148 1003545 B ATOM 5251 C ILE B 205 18454 19589 53466 1005735 B ATOM 5336 OH TYR B 216 13763 23175 58566 1003545 B ATOM 5252 O ILE B 205 17564 19900 52680 1005735 B ATOM 5337 C TYR B 216 11223 29853 55195 1003261 B ATOM 5253 N SER B 206 19633 19133 53063 1004965 B ATOM 5338 O TYR B 216 1015930168 55748 1003261 B ATOM 5254 CA SER B 206 19921 18993 51642 1004965 B ATOM 5339 N ASN B 217 11832 30621 54292 1003455 B ATOM 5255 CB SER B 206 21418 18836 51398 1005252 B ATOM 5340 CA ASN B 217 11283 31913 53917 1003455 B ATOM 5256 OG SER B 206 22095 20031 51716 1005252 B ATOM 5341 CB ASN B 217 9980 31735 53132 1003938 B ATOM 5257 C SER B 206 19201 17788 51081 1004965 B ATOM 5342 CG ASN B 217 10182 31001 51829 1003411 B ATOM 5258 O SER B 206 18993 17691 49870 1004965 B ATOM 5343 ODl ASN B 217 9521 29999 51576 1003411 B ATOM 5259 N ARG B 207 18825 16867 51961 1004908 B ATOM 5344 ND2 ASN B 217 11094 31490 50994 1003411 B ATOM 5260 CA ARG B 207 18124 15673 51535 1004908 B ATOM 5345 C ASN B 217 1099832720 55177 1003455 B ATOM 5261 CB ARG B 207 18536 14474 52389 1006941 B ATOM 5346 O ASN B 217 10003 33451 55244 1003455 B ATOM 5262 CG ARG B 207 19905 13945 52046 1006941 B ATOM 5347 N PHE B 218 11874 32602 56172 1002807 B ATOM 5263 CD ARG B 207 19996 1245852299 1006941 B ATOM 5348 CA PHE B 218 1165733298 57428 1002807 B ATOM 5264 NE ARG B 207 20131 12122 53715 1006941 B ATOM 5349 CB PHE B 218 1272732929 58443 1003929 B ATOM 5265 CZ ARG B 207 19742 10962 54246 1006941 B ATOM 5350 CG PHE B 218 1250033549 59782 1003581 B ATOM 5266 NHl ARG B 207 19187 10034 53473 1006941 B ATOM 5351 CDl PHE B 218 1164632951 60699 1003581 B ATOM 5267 NH2 ARG B 207 19913 10725 55546 1006941 B ATOM 5352 CD2 PHE B 218 13098 34760 60107 1003581 B ATOM 5268 C ARG B 207 16616 15862 51594 1004908 B ATOM 5353 CEl PHE B 218 11387 33548 61924 1003581 B ATOM 5269 O ARG B 207 15868 1490651433 1004908 B ATOM 5354 CE2 PHE B218 128473536861323 1003581 B ATOM 5270 N SER B 208 16168 17095 51831 1004655 B ATOM 5355 CZ PHE B 218 11986 34758 62239 1003581 B ATOM 5271 CA SER B 208 14739 17382 51901 1004655 B ATOM 5356 C PHE B 218 11594 34819 57325 1002807 B ATOM 5272 CB SER B 208 14334 17738 53320 1004408 B ATOM 5357 O PHE B 218 10656 35444 57830 1002807 B ATOM 5273 OG SER B 208 12932 17918 53392 1004408 B ATOM 5358 N ASN B 219 1259435418 56693 1003700 B ATOM 5274 C SER B 208 14372 18523 50963 1004655 B ATOM 5359 CA ASN B 219 12590 36863 56565 1003700 B ATOM 5275 O SER B 208 1405O 19632 51392 1004655 B ATOM 5360 CB ASN B 219 1378637351 55753 1004042 B ATOM 5276 N PRO B 209 14406 18249 49654 1003887 B ATOM 5361 CG ASN B 219 15102 36913 56340 1003205 B ATOM 5277 CD PRO B 209 14657 16892 49138 1004788 B ATOM 5362 ODl ASN B 219 15266 36854 57558 1003205 B ATOM 5278 CA PRO B 209 14105 19168 48552 1003887 B ATOM 5363 ND2 ASN B 219 1605736616 55475 1003205 B ATOM 5279 CB PRO B 209 13992 18235 47350 1004788 B ATOM 5364 C ASN B 219 1129737317 55903 1003700 B ATOM 5280 CG PRO B 209 14952 17161 47678 1004788 B ATOM 5365 O ASN B 219 1068938295 56338 1003700 B ATOM 5281 C PRO B 209 12838 19979 48729 1003887 B ATOM 5366 N PHE B 220 1087036613 54856 1004213 B ATOM 5282 O PRO B 209 127232106848197 1003887 B ATOM 5367 CA PHE B 220 963036961 54172 1004213 B ATOM 5283 N HIS B 210 11886 19439 49474 1004048 B ATOM 5368 CB PHE B 220 931635960 53058 1004565 B ATOM 5284 CA HIS B 210 1062320115 49649 1004048 B ATOM 5369 CG PHE B 220 7908 36061 52536 1003863 B ATOM 5285 CB HIS B 210 9496 1910749480 1004525 B ATOM 5370 CDl PHE B 220 7580 36976 51559 I 003863 B ATOM 5286 CG HIS B 210 9448 18506 48112 1004525 B ATOM 5371 CD2 PHE B 220 6889 35270 53059 1003863 B ATOM 5287 CD2 HIS B 210 9794 17274 47668 1004525 B ATOM 5372 CEl PHE B 220 627037128 51094 1003863 B ATOM 5288 NDl HIS B 210 9065 1922446998 1004525 B ATOM 5373 CE2 PHE B 220 556635412 52603 1003863 B ATOM 5289 CEl HIS B 210 9178 18461 45927 1004525 B ATOM 5374 CZ PHE B 220 526936354 51612 1003863 B ATOM 5290 NE2 HIS B 21O 9620 1727446306 1004525 B ATOM 5375 C PHE B 220 8460 36979 55146 1004213 B ATOM 5291 C HIS B 210 10462 20927 50927 1004048 B ATOM 5376 O PHE B 220 7774 37988 55283 1004213 B ATOM 5292 O HIS B 210 9369 21426 51232 1004048 B ATOM 5377 N TRP B 221 8234 35856 55819 1003906 B ATOM 5293 N THR B 211 1154621062 51680 1004133 B ATOM 5378 CA TRP B 221 713035747 56762 1003906 B ATOM 5294 CA THR B 211 1151221898 52865 1004133 B ATOM 5379 CB TRP B 221 699434299 57246 1004205 B ATOM 5295 CB THR B 211 1257721494 53870 1005975 B ATOM 5380 CG TRP B 221 6443 33383 56205 1003520 B ATOM 5296 OGl THR B 211 12329 20157 54318 1005975 B ATOM 5381 CD2 TRP B 221 515633480 55578 1003520 B ATOM 5297 CG2 THR B 211 1254722429 55060 1005975 B ATOM 5382 CE2 TRP B 221 507632441 54624 1003520 B ATOM 5298 C THR B 211 1186623267 52280 1004133 B ATOM 5383 CE3 TRP B 221 4061 34346 55731 1003520 B ATOM 5299 O THR B 211 12883 23406 51596 1004133 B ATOM 5384 CDl TRP B 221 7073 32312 55626 1003520 B ATOM 5300 N PRO B 212 11031 24289 52518 1004060 B ATOM 5385 NEl TRP B 221 625631744 54676 1003520 B ATOM 5301 CD PRO B 212 9869 24251 53417 1004199 B ATOM 5386 CZ2 TRP B 221 394732245 53823 1003520 B 65251/C766

ATOM 5387 CZ3 TRP B 221 293634149 54933 1003520 B ATOM 5472 OEl GLU B 231 -1608 48617 59132 10012196 B ATOM 5388 CH2 TRP B 221 28943310453989 1003520 B ATOM 5473 OE2 GLU B 231 -1756 48069 57008 10012196 B ATOM 5389 C TRP B 221 7241 36696 57954 1003906 B ATOM 5474 C GLU B 231 -3661 46062 61923 1005976 B ATOM 5390 O TRP B 221 6271 37367 58317 1003906 B ATOM 5475 O GLU B 231 -4611 46778 62239 1005976 B ATOM 5391 N TYR B 222 8413 36755 58572 1004648 B ATOM 5476 N ILE B 232 -352444821 62366 1005919 B ATOM 5392 CA TYR B 222 857437643 59710 1004648 B ATOM 5477 CA ILE B 232 -4498 44222 63263 1005919 B ATOM 5393 CB TYR B 222 10033 37738 60123 1003081 B ATOM 5478 CB ILE B 232 -4108 42769 63620 1008054 B ATOM 5394 CG TYR B 222 10243 3882461141 1002938 B ATOM 5479 CG2 ILE B 232 -490642277 64816 1005059 B ATOM 5395 CDl TYR B 222 9886 38631 62477 1002938 B ATOM 5480 CGl ILE B 232 435741857 62426 1005059 B ATOM 5396 CEl TYR B 222 10021 39652 63402 1002938 B ATOM 5481 CDl ILE B 232 -397640411 62691 1005059 B ATOM 5397 CD2 TYR B 222 1074040066 60762 1002938 B ATOM 5482 C ILE B 232 -464045020 64555 1005919 B ATOM 5398 CE2 TYR B 222 1087741094 61674 1002938 B ATOM 5483 O ILE B 232 -5722 45074 65142 1005919 B ATOM 5399 CZ TYR B 222 105134088462991 1002938 B ATOM 5484 N ASN B 233 -3558 4564464999 1008045 B ATOM 5400 OH TYR B 222 10613 41922 63891 1002938 B ATOM 5485 CA ASN B 233 -360746402 66237 1008045 B ATOM 5401 C TYR B 222 8088 39049 59359 1004648 B ATOM 5486 CB ASN B 233 -222446451 66886 1007911 B ATOM 5402 O TYR B 222 7274 39657 60054 1004648 B ATOM 5487 CG ASN B 233 -1803 45108 67463 1006803 B ATOM 5403 N SER B 223 861439558 58263 1003483 B ATOM 5488 ODl ASN B 233 -2639 44322 67916 1006803 B ATOM 5404 CA SER B 223 826440877 57812 1003483 B ATOM 5489 ND2 ASN B 233 -0501 44847 67467 1006803 B ATOM 5405 CB SER B 223 9092 41206 56596 1003531 B ATOM 5490 C ASN B 233 -416947815 66127 1008045 B ATOM 5406 OG SER B 223 8658 42435 56067 1003393 B ATOM 5491 O ASN B 233 -4433 48456 67148 1008045 B ATOM 5407 C SER B 223 6779 41077 57489 1003483 B ATOM 5492 N LYS B 234 -4363 48311 64908 1009085 B ATOM 5408 O SER B 223 615642043 57933 1003483 B ATOM 5493 CA LYS B 234 -491449653 64746 1009085 B ATOM 5409 N LEU B 224 6215 40164 56705 1004187 B ATOM 5494 CB LYS B 234 4802 50110 63294 1006367 B ATOM 5410 CA LEU B 224 481840256 56321 1004187 B ATOM 5495 CG LYS B 234 -3373 50460 62920 1006367 B ATOM 5411 CB LEU B 224 4505 39231 55241 1005824 B ATOM 5496 CD LYS B 234 3246 50940 61491 I 006367 B ATOM 5412 CG LEU B 224 306039279 54755 1003548 B ATOM 5497 CE LYS B 234 -1801 51315 61192 1006367 B ATOM 5413 CDl LEU B 224 267740680 54321 1003548 B ATOM 5498 NZ LYS B 234 -1579 51662 59755 1006367 B ATOM 5414 CD2 LEU B 224 290638315 53613 1003548 B ATOM 5499 C LYS B 234 -635649720 65243 1009085 B ATOM 5415 C LEU B 224 389040062 57510 1004187 B ATOM 5500 O LYS B 234 -6714 50660 65945 1009085 B ATOM 5416 O LEU B 224 281040649 57558 1004187 B ATOM 5501 N ASN B 235 -718648743 64882 1009211 B ATOM 5417 N MET B 225 4306 39238 58469 1005173 B ATOM 5502 CA ASN B 235 -8553 48719 65394 1009211 B ATOM 5418 CA MET B 225 348939001 59645 1005173 B ATOM 5503 CB ASN B 235 -944747748 64601 10014906 B ATOM 5419 CB MET B 225 3949 37750 60370 1007383 B ATOM 5504 CG ASN B 235 -10842 47597 65219 10014906 B ATOM 5420 CG MET B 225 3675 36501 59588 1004255 B ATOM 5505 ODl ASN B 235 -10961 47479 66438 10014906 B ATOM 5421 SD MET B 225 4035 35041 60525 1004255 B ATOM 5506 ND2 ASN B 235 -11898 47589 64403 10014906 B ATOM 5422 CE MET B 225 283935210 61865 1004255 B ATOM 5507 C ASN B 235 -834048199 66819 1009211 B ATOM 5423 C MET B 225 3588 40198 60561 1005173 B ATOM 5508 O ASN B 235 -801447030 67018 1009211 B ATOM 5424 O MET B 225 2629 40556 61238 1005173 B ATOM 5509 N ASP B 236 -851049069 67806 1009564 B ATOM 5425 N LYS B 226 475940822 60582 1005123 B ATOM 5510 CA ASP B 236 -828748699 69197 1009564 B ATOM 5426 CA LYS B 226 495941995 61410 1005123 B ATOM 5511 CB ASP B 236 -8478 49935 70082 10013632 B ATOM 5427 CB LYS B 226 639642493 61292 1009584 B ATOM 5512 CG ASP B 236 -770949845 71386 10013632 B ATOM 5428 CG LYS B 226 6683 43734 62112 1004730 B ATOM 5513 ODl ASP B 236 -8088 49033 72255 10013632 B ATOM 5429 CD LYS B 226 806644241 61811 1004730 B ATOM 5514 OD2 ASP B 236 -6717 50586 71538 10013632 B ATOM 5430 CE LYS B 226 8271 45595 62407 1004730 B ATOM 5515 C ASP B 236 -912447531 69739 1009564 B ATOM 5431 NZ LYS B 226 961846118 62042 1004730 B ATOM 5516 O ASP B 236 -8888 47069 70857 1009564 B ATOM 5432 C LYS B 226 399443048 60897 I 005123 B ATOM 5517 N SER B 237 -1008847043 68963 1009413 B ATOM 5433 O LYS B 226 3301 43696 61677 1005123 B ATOM 5518 CA SER B 237 1091945927 69421 1009413 B ATOM 5434 N GLU B 227 394043195 59575 1004999 B ATOM 5519 CB SER B 237 -1235446079 68914 10011152 B ATOM 5435 CA GLU B 227 3045 44159 58936 1004999 B ATOM 5520 OG SER B 237 -12445 45757 67537 10011152 B ATOM 5436 CB GLU B 227 318544094 57421 10012536 B ATOM 5521 C SER B 237 -1036644578 68961 1009413 B ATOM 5437 CG GLU B 227 2381 45156 56707 10010116 B ATOM 5522 O SER B 237 -1097943534 69190 1009413 B ATOM 5438 CD GLU B 227 223844893 55221 10010116 B ATOM 5523 N THR B 238 -9208 44609 68306 1009832 B ATOM 5439 OEl GLU B 227 327044679 54545 10010116 B ATOM 5524 CA THR B 238 -856043394 67816 1009832 B ATOM 5440 OE2 GLU B 227 108844907 54726 10010116 B ATOM 5525 CB THR B 238 -839743416 66282 1009539 B ATOM 5441 C GLU B 227 160243848 59317 1004999 B ATOM 5526 OGl THR B 238 -960843871 65676 1009539 B ATOM 5442 O GLU B 227 085044722 59729 1004999 B ATOM 5527 CG2 THR B 238 -8081 42017 65761 1009539 B ATOM 5443 N THR B 228 1223 42585 59185 1004768 B ATOM 5528 C THR B 238 -716743261 68429 1009832 B ATOM 5444 CA THR B 228 -012742157 59518 1004768 B ATOM 5529 O THR B 238 -6635 42160 68542 1009832 B ATOM 5445 CB THR B 228 031440657 59250 1005319 B ATOM 5530 N LYS B 239 -659244398 68812 1009458 B ATOM 5446 OGl THR B 228 -00174037457882 1003918 B ATOM 5531 CA LYS B 239 -5263 44457 69409 1009458 B ATOM 5447 CG2 THR B 228 -174040239 59540 1003918 B ATOM 5532 CB LYS B 239 -5219 45567 70463 10010241 B ATOM 5448 C THR B 228 -048242413 60974 1004768 B ATOM 5533 CG LYS B 239 -3851 45772 71101 10010241 B ATOM 5449 O THR B 228 -1601 42787 61277 1004768 B ATOM 5534 CD LYS B 239 -381647040 71934 10010241 B ATOM 5450 N LEU B 229 0462 42195 61877 1005406 B ATOM 5535 CE LYS B 239 -403948269 71065 10010241 B ATOM 5451 CA LEU B 229 018442397 63283 1005406 B ATOM 5536 NZ LYS B 239 -401049520 71871 10010241 B ATOM 5452 CB LEU B 229 1331 41861 64135 1006778 B ATOM 5537 C LYS B 239 -4852 43125 70028 1009458 B ATOM 5453 CG LEU B 229 115441961 65654 1003966 B ATOM 5538 O LYS B 239 -554642595 70895 1009458 B ATOM 5454 CDl LEU B 229 -0251 41538 66079 1003966 B ATOM 5539 N THR B 240 -372242589 69568 1005935 B ATOM 5455 CD2LEUB229 2205 41094 66324 1003966 B ATOM 5540 CA THR B 240 3213 41309 70053 1005935 B ATOM 5456 C LEU B 229 -005043870 63569 1005406 B ATOM 5541 CB THR B 240 -3427 40190 69024 1007787 B ATOM 5457 O LEU B 229 -0925 44218 64361 1005406 B ATOM 5542 OGl THR B 240 -4803 40153 68638 1007787 B ATOM 5458 N GLU B 230 071944738 62920 1006343 B ATOM 5543 CG2 THR B 240 -3052 38851 69617 1007787 B ATOM 5459 CA GLU B 230 056046179 63113 1006343 B ATOM 5544 C THR B 240 -1725 41354 70363 1005935 B ATOM 5460 CB GLU B 230 164446938 62355 10013598 B ATOM 5545 O THR B 240 -097842145 69796 1005935 B ATOM 5461 CG GLU B 230 302746762 62958 10010044 B ATOM 5546 N THR B 241 -1312 40478 71268 1006460 B ATOM 5462 CD GLU B 230 4093 47547 62223 10010044 B ATOM 5547 CA THR B 241 0069 40365 71688 1006460 B ATOM 5463 OEl GLU B 230 388848758 62013 10010044 B ATOM 5548 CB THR B 241 0183 39408 72876 10011233 B ATOM 5464 OE2 GLU B 230 513846962 61862 10010044 B ATOM 5549 OGl THR B 241 -0780 39771 73863 1007203 B ATOM 5465 C GLU B 230 -082446642 62663 1006343 B ATOM 5550 CG2 THR B 241 1567 39460 73480 1007203 B ATOM 5466 O GLU B 230 -1495 47373 63367 1006343 B ATOM 5551 C THR B 241 0911 39786 70557 1006460 B ATOM 5467 N GLU B 231 -125646202 61494 1005976 B ATOM 5552 O THR B 241 20064027070276 1006460 B ATOM 5468 CA GLU B 231 257046568 60979 1005976 B ATOM 5553 N SER B 242 039238748 69907 1005639 B ATOM 5469 CB GLU B 231 278045957 59594 10014572 B ATOM 5554 CA SER B 242 1129 38076 68849 1005639 B ATOM 5470 CG GLU B 231 -169746302 58592 10012196 B ATOM 5555 CB SER B 242 1953 36940 69450 1009671 B ATOM 5471 CD GLU B 231 -168847768 58219 10012196 B ATOM 5556 OG SER B 242 1093 35991 70054 1006923 B 65251/C766

ATOM 5557 C SER B 242 0266 37503 67733 1005639 B ATOM 5642 CDl LEU B 254 -7987 3096 56758 1004807 B ATOM 5558 O SER B 242 -0964 37453 67822 1005639 B ATOM 5643 CD2 LEU B 254 -5576 3071 56109 1004807 B ATOM 5559 N LEU B 243 0950 37055 66685 1005364 B ATOM 5644 C LEU B 254 -5588 7337 56851 1005664 B ATOM 5560 CA LEU B 243 0322 36463 65518 1005364 B ATOM 5645 O LEU B 254 -5583 7697 55676 1005664 B ATOM 5561 CB LEU B 243 0342 37470 64381 1006190 B ATOM 5646 N LEU B 255 -5853 8158 57864 1004385 B ATOM 5562 CG LEU B 243 -0509 37129 63163 1003803 B ATOM 5647 CA LEU B 255 6160 9568 57636 1004385 B ATOM 5563 CDl LEU B 243 -1949 36968 63606 1003803 B ATOM 5648 CB LEU B 255 -6757 10187 58898 1005486 B ATOM 5564 CD2 LEU B 243 -0403 38224 62123 1003803 B ATOM 5649 CG LEU B 255 -7953 9457 59510 1005486 B ATOM 5565 C LEU B 243 1 105 35202 65123 1005364 B ATOM 5650 CDl LEU B 255 -8469 10251 60705 1005486 B ATOM 5566 O LEU B 243 2339 35191 65158 1005364 B ATOM 5651 CD2 LEU B 255 -9049 9291 58476 1005486 B ATOM 5567 N SER B 244 0394 34140 64759 1005057 B ATOM 5652 C LEU B 255 -4934 10368 57212 1004385 B ATOM 5568 CA SER B 244 1053 32901 64374 1005057 B ATOM 5653 O LEU B 255 -3805 10048 57579 1004385 B ATOM 5569 CB SER B 244 0879 31836 65458 1004431 B ATOM 5654 N PHE B 256 -5161 11405 56423 I 003772 B ATOM 5570 OO SER B 244 1513 32196 66668 1004646 B ATOM 5655 CA PHE B 256 -4069 12244 55969 1003772 B ATOM 5571 C SER B 244 0553 32323 63058 1005057 B ATOM 5656 CB PHE B 256 -3274 11525 54875 1004641 B ATOM 5572 O SER B 244 -0635 32397 62739 1005057 B ATOM 5657 CG PHE B 256 -4040 11305 53602 1004342 B ATOM 5573 N LEU B 245 1477 31755 62290 1004459 B ATOM 5658 CDl PHE B 256 -3931 12193 52539 1004342 B ATOM 5574 CA LEU B 245 1 141 31098 61035 1004459 B ATOM 5659 CD2 PHE B 256 -4869 10196 53456 1004342 B ATOM 5575 CB LEU B 245 2028 31604 59910 1004230 B ATOM 5660 CEl PHE B 256 -4631 11975 51355 1004342 B ATOM 5576 CG LEU B 245 1782 30881 58592 1002629 B ATOM 5661 CE2 PHE B 256 5578 9976 52262 1004342 B ATOM 5577 CDl LEU B 245 0308 31012 58177 1002629 B ATOM 5662 CZ PHE B 256 -5456 10862 51220 1004342 B ATOM 5578 CD2 LEU B 245 2699 31450 57530 1002629 B ATOM 5663 C PHE B 256 -4615 13570 55457 1003772 B ATOM 5579 C LEU B 245 1 387 29597 61267 1004459 B ATOM 5664 O PHE B 256 -5692 13613 54871 1003772 B ATOM 5580 O LEU B 245 2528 29159 61377 1004459 B ATOM 5665 N GLY B 257 -3881 14651 55700 1004286 B ATOM 5581 N ILE B 246 0310 28825 61374 1003961 B ATOM 5666 CA GLY B 257 -4315 15958 55242 1004286 B ATOM 5582 CA ILE B 246 0406 27393 61614 1003961 B ATOM 5667 C GLY B 257 -3277 17019 55536 1004286 B ATOM 5583 CB ILE B 246 -0610 26946 62677 1004892 B ATOM 5668 O GLY B 257 -2215 16712 56080 1004286 B ATOM 5584 CG2 ILE B 246 -0449 25470 62979 1003196 B ATOM 5669 N SER B 258 -3579 18265 55177 1004261 B ATOM 5585 CGl ILE B 246 -0410 27767 63954 1003196 B ATOM 5670 CA SER B 258 -2661 19366 55414 1004261 B ATOM 5586 CDl ILE B 246 0991 27695 64519 1003196 B ATOM 5671 CB SER B 258 -1914 19720 54136 1003972 B ATOM 5587 C ILE B 246 0124 26641 60333 1003961 B ATOM 5672 OG SER B 258 -2804 20269 53187 1004984 B ATOM 5588 O ILE B 246 -0965 26743 59780 1003961 B ATOM 5673 C SER B 258 -3441 20577 55901 1004261 B ATOM 5589 N THR B 247 1 100 25886 59850 1003819 B ATOM 5674 O SER B 258 -4656 20644 55750 1004261 B ATOM 5590 CA THR B 247 0908 25134 58626 1003819 B ATOM 5675 N TYR B 259 -2746 21541 56483 1003588 B ATOM 5591 CB THR B 247 1407 25922 57421 1 003928 B ATOM 5676 CA TYR B 259 -3423 22717 56983 1003588 B ATOM 5592 OGl THR B 247 0976 25264 56230 1003652 B ATOM 5677 CB TYR B 259 -3878 22473 58426 1004790 B ATOM 5593 CG2 THR B 247 2928 26024 57428 1003652 B ATOM 5678 CG TYR B 259 -2752 22017 59313 1004365 B ATOM 5594 C THR B 247 1 663 23821 58733 1003819 B ATOM 5679 CDI TYR B 259 -1 840 22935 59848 1004365 B ATOM 5595 O THR B 247 2683 23748 59419 1003819 B ATOM 5680 CEl TYR B 259 -0735 22514 60572 1004365 B ATOM 5596 N GLY B 248 1 154 22783 58073 1003437 B ATOM 5681 CD2 TYR B 259 -2529 20664 59537 1004365 B ATOM 5597 CA GLY B 248 1794 21477 58136 1003437 B ATOM 5682 CE2 TYR B 259 -1426 20234 60256 1004365 B ATOM 5598 C GLY B 248 0877 20381 57631 1003437 B ATOM 5683 CZ TYR B 259 -0530 21 162 60767 1004365 B ATOM 5599 O GLY B 248 -0180 20671 57063 1003437 B ATOM 5684 OH TYR B 259 0591 20726 61436 1004365 B ATOM 5600 N CYS B 249 1264 19125 57842 1003628 B ATOM 5685 C TYR B 259 2547 23957 56922 1003588 B ATOM 5601 CA CYS B 249 0447 18019 57371 1003628 B ATOM 5686 O TYR B 259 -1322 23883 56782 1003588 B ATOM 5602 CB CYS B 249 0871 17612 55962 1003770 B ATOM 5687 N GLY B 260 -3201 25102 57035 1004011 B ATOM 5603 SG CYS B 249 2438 16763 55945 1005647 B ATOM 5688 CA GLY B 260 -2503 26367 57001 1004011 B ATOM 5604 C CYS B 249 0554 16819 58281 1003628 B ATOM 5689 C GLY B 260 .3474 27426 57486 1004011 B ATOM 5605 O CYS B 249 1285 16847 59262 1003628 B ATOM 5690 O GLY B 260 -4399 27818 56771 1004011 B ATOM 5606 N TYR B 250 -0163 15753 57949 1004271 B ATOM 5691 N TYR B 261 -3281 27881 58715 1003698 B ATOM 5607 CA TYR B 250 -0142 14560 58775 1004271 B ATOM 5692 CA TYR B 261 -4156 28891 59261 1003698 B ATOM 5608 CB TYR B 250 -1089 14741 59941 1004147 B ATOM 5693 CB TYR B 261 -5252 28237 60085 1005326 B ATOM 5609 CG TYR B 250 -2520 14924 59492 1003182 B ATOM 5694 CG TYR B 261 -4758 27438 61261 1003705 B ATOM 5610 CDl TYR B 250 -3374 13829 59340 10031 82 B ATOM 5695 CDl TYR B 261 -4520 28043 62490 1003705 B ATOM 5611 CEI TYR B 250 -4681 13994 58892 10031 82 B ATOM 5696 CEl TYR B 261 -4106 27300 63593 1003705 B ATOM 5612 CD2 TYR B 250 -3012 16187 59187 10031 82 B ATOM 5697 CD2 TYR B 261 -4561 26072 61 158 1003705 B ATOM 5613 CE2 TYR B 250 -4310 16367 58738 10031 82 B ATOM 5698 CE2 TYR B 261 -4147 25318 62245 1003705 B ATOM 5614 CZ TYR B 250 -5145 15271 58588 1003182 B ATOM 5699 CZ TYR B 261 -3923 25932 63463 1003705 B ATOM 5615 OH TYR B 250 6430 15461 58108 1003182 B ATOM 5700 OH TYR B 261 -3536 25168 64555 1003705 B ATOM 5616 C TYR B 250 -0554 13302 58032 1004271 B ATOM 5701 C TYR B 261 -3389 29893 60098 1003698 B ATOM 5617 O TYR B 250 -1270 13359 57033 1004271 B ATOM 5702 O TYR B 261 -2234 29663 60479 1003698 B ATOM 5618 N GLU B 251 -0082 12173 58546 1005493 B ATOM 5703 N VAL B 262 -4040 31022 60360 1004503 B ATOM 5619 CA GLU B 251 -0397 10858 58033 005493 B ATOM 5704 CA VAL B 262 -3449 32093 61 142 1004503 B ATOM 5620 CB GLU B 251 0768 10280 57241 0010262 B ATOM 5705 CB VAL B 262 -3496 33417 60371 1004187 B ATOM 5621 CG GLU B 251 0447 10141 55776 005624 B ATOM 5706 CGl VAL B 262 -3125 34558 61290 1003336 B ATOM 5622 CD GLU B 251 1520 9406 54990 1005624 B ATOM 5707 CG2 VAL B 262 -2537 33368 59201 1003336 B ATOM 5623 OEl GLU B 251 1854 8258 55367 1005624 B ATOM 5708 C VAL B 262 -4219 32265 62432 1004503 B ATOM 5624 OE2 GLU B 251 2024 9971 53986 1005624 B ATOM 5709 O VAL B 262 -5418 32472 62398 1004503 B ATOM 5625 C GLU B 251 -0636 10050 59305 1005493 B ATOM 5710 N GLU B 263 -3542 32160 63571 1005507 B ATOM 5626 O GLU B 251 0258 9353 59799 1005493 B ATOM 5711 CA GLU B 263 -4209 32350 64852 1005507 B ATOM 5627 N THR B 252 -1 842 10190 59852 1004601 B ATOM 5712 CB GLU B 263 -4159 31096 65723 1008676 B ATOM 5628 CA THR B 252 -2248 9505 61076 1004601 B ATOM 5713 CG GLU B 263 -2792 30538 65954 1007336 B ATOM 5629 CB THR B 252 -3164 10415 61928 1005302 B ATOM 5714 CD GLU B 263 -2823 29299 66831 1007336 B ATOM 5630 OGl THR B 252 -2526 11680 62139 1005302 B ATOM 5715 OEl GLU B 263 -3737 28454 66656 1007336 B ATOM 5631 CG2 THR B 252 -3459 9782 63260 1005302 B ATOM 5716 OE2 GLU B 263 -1919 29165 67687 1007336 B ATOM 5632 C THR B 252 -3026 8261 60662 1004601 B ATOM 5717 C GLU B 263 -3593 33514 65586 1005507 B ATOM 5633 O THR B 252 -4212 8339 60360 1004601 B ATOM 5718 O GLU B 263 -2471 33934 65301 1005507 B ATOM 5634 N GLY B 253 -2357 7115 60646 1006107 B ATOM 5719 N THR B 264 -4358 34036 66531 1005977 B ATOM 5635 CA GLY B 253 -3031 5901 60234 1006107 B ATOM 5720 CA THR B 264 -3979 35191 67324 1005977 B ATOM 5636 C GLY B 253 -3498 6060 58797 1006107 B ATOM 5721 CB THR B 264 -5047 36285 67123 1007964 B ATOM 5637 O GLY B 253 -2727 6459 57926 1006107 B ATOM 5722 OGl THR B 264 -4564 37238 66175 1005857 B ATOM 5638 N LEU B 254 -4763 5758 58542 1005664 B ATOM 5723 CG2 THR B 264 5404 36967 68405 1005857 B ATOM 5639 CA LEU B 254 -5313 5890 57201 1005654 B ATOM 5724 C THR B 264 -3888 34779 68778 1005977 B ATOM 5640 CB LEU B 254 -6631 5119 57059 1004807 B ATOM 5725 O THR B 264 -4321 33685 69134 1005977 B ATOM 5641 CG LEU B 254 -6599 3599 57091 1004807 B ATOM 5726 N ALA B 265 -3309 35628 69620 1007163 B 65251/C766

ATOM 5727 CA ALA B 265 -3217 35301 71037 1007163 B ATOM 5812 OD2 ASP B 276 -12693 27873 49361 1009851 B ATOM 5728 CB ALA B 265 -2477 36395 71784 1008903 B ATOM 5813 C ASP B 276 -9491 29819 46647 1005753 B ATOM 5729 C ALA B 265 -4636 35146 71586 1007163 B ATOM 5814 O ASP B 276 -9642 30914 46107 1005753 B ATOM 5730 O ALA B 265 -4851 34487 72600 1007163 B ATOM 5815 N LYS B 277 -8315 29400 47115 1006628 B ATOM 5731 N ASN B 266 -5599 35749 70893 1009280 B ATOM 5816 CA LYS B 277 -7101 30221 47041 1006628 B ATOM 5732 CA ASN B 266 -7003 35691 71281 1009280 B ATOM 5817 CB LYS B 277 -6720 30467 45579 1008220 B ATOM 5733 CB ASN B 266 -7742 36928 70786 10014408 B ATOM 5818 CG LYS B 277 -6276 29208 44851 1006741 B ATOM 5734 CG ASN B 266 -7089 38201 71242 1008593 B ATOM 5819 CD LYS B 277 6220 29425 43351 1006741 B ATOM 5735 ODl ASN B 266 -6825 38378 72431 1008593 B ATOM 5820 CE LYS B 277 -5728 28187 42616 1006741 B ATOM 5736 ND2 ASN B 266 -6821 39102 70302 1008593 B ATOM 5821 NZ LYS B 277 -4255 27992 42773 1006741 B ATOM 5737 C ASN B 266 .7704 34453 70747 1009280 B ATOM 5822 C LYS B 277 -7293 31552 47772 1006628 B ATOM 5738 O ASN B 266 -8804 34139 71 181 1009280 B ATOM 5823 O LYS B 277 -6998 32618 47237 1006628 B ATOM 5739 N GLY B 267 -7077 33763 69798 I 005393 B ATOM 5824 N ARG B 278 -7794 31467 49002 1004739 B ATOM 5740 CA GLY B 267 -7665 32555 69244 1005393 B ATOM 5825 CA ARG B 278 -8057 32639 49832 1004739 B ATOM 5741 C GLY B 267 -7614 32473 67737 1005393 B ATOM 5826 CB ARG B 278 -9308 33351 49334 10010452 B ATOM 5742 O GLY B 267 -7225 33434 67087 1005393 B ATOM 5827 CG ARG B 278 -10572 32575 49615 1008915 B ATOM 5743 N PRO B 268 -8033 31340 67150 1005579 B ATOM 5828 CD ARG B 278 11760 33 163 48896 1008915 B ATOM 5744 CD PRO B 268 8797 30267 67807 1004267 B ATOM 5829 NE ARG B 278 -12998 32476 49258 1008915 B ATOM 5745 CA PRO B 268 -8023 31 146 65696 1005579 B ATOM 5830 CZ ARG B 278 -14138 32579 48581 1008915 B ATOM 5746 CB PRO B 268 -8826 29862 65508 1005856 B ATOM 5831 NHl ARG B 278 -14199 33344 47497 1008915 B ATOM 5747 CG PRO B 268 -9719 29832 66701 1004267 B ATOM 5832 NH2 ARG B 278 -15217 31917 48985 1008915 B ATOM 5748 C PRO B 268 -8612 32316 64945 1005579 B ATOM 5833 C ARG B 278 -8280 32192 51283 1004739 B ATOM 5749 O PRO B 268 -9639 32852 65335 1005579 B ATOM 5834 O ARG B 278 -8436 31002 51560 1004739 B ATOM 5750 N LEU B 269 -7949 32708 63866 1006157 B ATOM 5835 N PHE B 279 -8294 33139 52211 1005381 B ATOM 5751 CA LEU B 269 -8389 33830 63063 10061 57 B ATOM 5836 CA PHE B 279 8512 32784 53606 1005381 B ATOM 5752 CB LEU B 269 -7237 34825 62919 1009130 B ATOM 5837 CB PHE B 279 -7813 33768 54544 1005349 B ATOM 5753 CG LEU B 269 -7572 36238 62447 1005664 B ATOM 5838 CG PHE B 279 -6350 33518 54703 1003726 B ATOM 5754 CDl LEU B 269 -8635 36828 63351 1005664 B ATOM 5839 CDl PHE B 279 5424 34164 53891 1003726 B ATOM 5755 CD2 LEU B 269 -6322 37107 62465 1005664 B ATOM 5840 CD2 PHE B 279 5889 32641 55674 1003726 B ATOM 5756 C LEU B 269 -8904 33398 61686 1006157 B ATOM 5841 CEl PHE B 279 -4056 33940 54050 I 003726 B ATOM 5757 O LEU B 269 -10110 33412 61438 1006157 B ATOM 5842 CE2 PHE B 279 -4524 32411 55837 1003726 B ATOM 5758 N ALA B 270 -8000 33005 60795 1005191 B ATOM 5843 CZ PHE B 279 -3608 33062 55025 1003726 B ATOM 5759 CA ALA B 270 -8390 32600 59444 10051 91 B ATOM 5844 C PHE B 279 -9996 32778 53927 1005381 B ATOM 5760 CB ALA B 270 -8185 33770 58466 1002582 B ATOM 5845 O PHE B 279 -10780 33468 53279 1005381 B ATOM 5761 C ALA B 270 -7656 31363 58929 1005191 B ATOM 5846 N THR B 280 -10375 32002 54937 1006330 B ATOM 5762 O ALA B 270 -6467 31 154 59192 1005191 B ATOM 5847 CA THR B 280 -II 764 31921 55358 1006330 B ATOM 5763 N ARG B 271 -8380 30570 58154 1005273 B ATOM 5848 CB THR B 280 -12409 30619 54907 10010589 B ATOM 5764 CA ARG B 271 -7875 29329 57584 1005273 B ATOM 5849 OGl THR B 280 -12183 30439 53507 1008641 B ATOM 5765 CB ARG B 271 -8876 28224 57923 10051 88 B ATOM 5850 CG2 THR B 280 -13900 30658 55172 1008641 B ATOM 5766 CG ARG B 271 8678 26939 57215 1004500 B ATOM 5851 C THR B 280 -11 842 31976 56873 1006330 B ATOM 5767 CD ARG B 271 -9784 25983 57575 1004500 B ATOM 5852 O THR B 280 -11036 31355 57561 I 006330 B ATOM 5768 NE ARG B 271 -9694 25519 58955 1004500 B ATOM 5853 N LYS B 281 -12815 32723 57383 1005098 B ATOM 5769 CZ ARG B 271 -10507 25893 59934 1004500 B ATOM 5854 CA LYS B 281 -13023 32864 58818 1005098 B ATOM 5770 NHl ARG B 271 -11487 26750 59696 1004500 B ATOM 5855 CB LYS B 281 -14334 33612 59066 10011008 B ATOM 5771 NH2 ARG B 271 -10346 25394 61 148 1004500 B ATOM 5856 CG LYS B 281 -15431 33249 58067 1008602 B ATOM 5772 C ARG B 271 -7709 29490 56073 1005273 B ATOM 5857 CD LYS B 281 -16752 32890 58745 1008602 B ATOM 5773 O ARG B 271 -8568 30060 55412 1005273 B ATOM 5858 CE LYS B 281 17376 34075 59466 1008602 B ATOM 5774 N TYR B 272 -6602 29003 55527 1004431 B ATOM 5859 NZ LYS B 281 -18691 33715 60074 1008602 B ATOM 5775 CA TYR B 272 -6355 29134 54090 1004431 B ATOM 5860 C LYS B 281 -13060 31505 59530 1005098 B ATOM 5776 CB TYR B 272 -4858 29287 53812 1004463 B ATOM 5861 O LYS B 281 13598 30530 59005 1005098 B ATOM 5777 CG TYR B 272 -4541 29474 52342 1004210 B ATOM 5862 N MET B 282 -12468 31441 60720 1005353 B ATOM 5778 CDl TYR B 272 -4643 30727 51739 1004210 B ATOM 5863 CA MET B 282 -12460 30214 61511 1005353 B ATOM 5779 CEl TYR B 272 4379 30897 50381 1004210 B ATOM 5864 CB MET B 282 -11076 29936 62092 1006615 B ATOM 5780 CD2 TYR B 272 -4163 28394 51547 1004210 B ATOM 5865 CG MET B 282 -10032 29505 61084 1006615 B ATOM 5781 CE2 TYR B 272 -3895 28557 50190 1004210 B ATOM 5866 SD MET B 282 -8582 28753 61888 1006615 B ATOM 5782 CZ TYR B 272 -4007 29809 49614 1004210 B ATOM 5867 CE MET B 282 -7605 30165 62126 1006615 B ATOM 5783 OH TYR B 272 -3767 29987 48268 1004210 B ATOM 5868 C MET B 282 -13432 30380 62663 1005353 B ATOM 5784 C TYR B 272 -6864 27935 53320 1004431 B ATOM 5869 O MET B 282 -13717 29428 63376 1005353 B ATOM 5785 O TYR B 272 -6451 26814 53580 1004431 B ATOM 5870 N THR B 283 -13922 31605 62836 1006875 B ATOM 5786 N HIS B 273 -7750 28161 52361 1005919 B ATOM 5871 CA THR B 283 -14856 31955 63897 1006875 B ATOM 5787 CA HIS B 273 -8282 27057 51576 1005919 B ATOM 5872 CB THR B 283 -14143 32744 65004 1008327 B ATOM 5788 CB HIS B 273 9793 27193 51406 10014123 B ATOM 5873 OGl THR B 283 -13158 31911 65617 1008327 B ATOM 5789 CG HIS B 273 -10558 26850 52643 10012196 B ATOM 5874 CG2 THR B 283 -15123 33206 66059 1008327 B ATOM 5790 CD2 HIS B 273 -11395 27586 53411 10012196 B ATOM 5875 C THR B 283 -15956 32836 63318 1006875 B ATOM 5791 NDl HIS B 273 -10471 25615 53248 10012196 B ATOM 5876 O THR B 283 -15773 33465 62274 1006875 B ATOM 5792 CEl HIS B 273 -11221 25605 54336 10012196 B ATOM 5877 N HIS B 284 -17101 32877 63995 1008680 B ATOM 5793 NE2 HIS B 273 -11792 26790 54458 10012196 B ATOM 5878 CA HIS B 284 -18226 33702 63560 1008680 B ATOM 5794 C HIS B 273 -7613 26920 50227 1005919 B ATOM 5879 CB HIS B 284 -19375 33585 64569 10014317 B ATOM 5795 O HIS B 273 -7636 27838 49410 1005919 B ATOM 5880 CG HIS B 284 18984 33937 65974 10014317 B ATOM 5796 N THR B 274 -6992 25762 50022 1004466 B ATOM 5881 CD2 HIS B 284 19381 34948 66783 10014317 B ATOM 5797 CA THR B 274 -6303 25430 48782 1004466 B ATOM 5882 NDl HIS B 284 -18055 33215 66694 100143 17 B ATOM 5798 CB THR B 274 -5754 23997 48877 1007454 B ATOM 5883 CEI HIS B 284 -17896 33766 67884 10014317 B ATOM 5799 OGl THR B 274 -4377 24056 49259 1006707 B ATOM 5884 NE2 HIS B 284 -18689 34820 67964 10014317 B ATOM 5800 CG2 THR B 274 -5915 23247 47562 1006707 B ATOM 5885 C HIS B 284 ^{■ ■} 17752 35152 63483 1008680 B ATOM 5801 C THR B 274 -7221 25572 47562 1004466 B ATOM 5886 O HIS B 284 -18139 35903 62592 1008680 B ATOM 5802 O THR B 274 -6796 26029 46504 1004466 B ATOM 5887 N LYS B 285 -16889 35513 64428 1007099 B ATOM 5803 N GLY B 275 -8481 25184 47717 1006142 B ATOM 5888 CA LYS B 285 -16326 36851 64552 1007099 B ATOM 5804 CA GLY B 275 -9424 25288 46620 1006142 B ATOM 5889 CB LYS B 285 -15223 36842 65613 10010980 B ATOM 5805 C GLY B 275 -9718 26717 46191 1006142 B ATOM 5890 CG LYS B 285 -15357 37921 66670 10010980 B ATOM 5806 O GLY B 275 -9398 27110 45072 1006142 B ATOM 5891 CD LYS B 285 -16604 37717 67518 10010980 B ATOM 5807 N ASP B 276 -10322 27494 47087 1005753 B ATOM 5892 CE LYS B 285 -16733 38792 68592 10010980 B ATOM 5808 CA ASP B 276 -10685 28880 46812 1005753 B ATOM 5893 NZ LYS B 285 -17940 38595 69441 10010980 B ATOM 5809 CB ASP B 276 -11575 29409 47937 10011951 B ATOM 5894 C LYS B 285 -15766 37426 63257 1007099 B ATOM 5810 CG ASP B 276 -12714 28470 48263 1009851 B ATOM 5895 O LYS B 285 -15802 38638 63056 1007099 B ATOM 5811 ODl ASP B 276 -13623 28319 47421 1009851 B ATOM 5896 N GLY B 286 15248 36564 62386 1007992 B 65251/C766

ATOM 5897 CA GLY B 286 -14664 37032 61 137 1007992 B ATOM 5982 ND2 ASN B 297 0016 42777 52506 1006942 B ATOM 5898 C GLY B 286 -13210 37421 61351 1007992 B ATOM 5983 C ASN B 297 -0941 42762 48376 1005739 B ATOM 5899 O GLY B 286 -12679 37247 62450 1007992 B ATOM 5984 O ASN B 297 -1 119 41 814 47614 1005739 B ATOM 5900 N PHE B 287 -12555 37938 60314 1007066 B ATOM 5985 N THR B 298 0055 43620 48238 1005864 B ATOM 5901 CA PHE B 287 -11 153 38353 60428 1007066 B ATOM 5986 CA THR B 298 1005 43514 47150 1005864 B ATOM 5902 CB PHE B 287 -10216 37220 59998 1004130 B ATOM 5987 CB THR B 298 1983 44713 47197 1006216 B ATOM 5903 CG PHE B 287 -10252 36914 58524 1004130 B ATOM 5988 OGl THR B 298 3172 44397 46465 1006216 B ATOM 5904 CDl PHE B 287 -9468 37642 57628 1004130 B ATOM 5989 CG2 THR B 298 2339 45052 48632 1006216 B ATOM 5905 CD2 PHE B 287 -11081 35898 58023 1004130 B ATOM 5990 C THR B 298 1783 42191 47130 1005864 B ATOM 5906 CEl PHE B 287 -9511 37360 56241 1004130 B ATOM 5991 O THR B 298 2230 41744 46078 1005864 B ATOM 5907 CE2 PHE B 287 -11128 35613 56647 1004130 B ATOM 5992 N LEU B 299 1930 41553 48284 1004695 B ATOM 5908 CZ PHE B 287 -10346 36342 55755 1004130 B ATOM 5993 CA LEU B 299 2673 40292 48364 1004695 B ATOM 5909 C PHE B 287 -10866 39598 59600 1007066 B ATOM 5994 CB LEU B 299 3545 40279 49614 1004604 B ATOM 5910 O PHE B 287 -11373 39751 58491 1007066 B ATOM 5995 CG LEU B 299 4640 41338 49626 1004604 B ATOM 5911 N PRO B 288 -10036 40507 60130 1005608 B ATOM 5996 CDl LEU B 299 5308 41353 50974 1004604 B ATOM 5912 CD PRO B 288 -9306 40386 61407 1006661 B ATOM 5997 CD2 LEU B 299 5622 41043 48519 1004604 B ATOM 5913 CA PRO B 288 -9681 41753 59437 1005608 B ATOM 5998 C LEU B 299 1 798 39042 48365 1004695 B ATOM 5914 CB PRO B 288 -8860 42506 60478 1006661 B ATOM 5999 O LEU B 299 2295 37935 48575 1004695 B ATOM 5915 CG PRO B 288 -8189 41396 61234 1006661 B ATOM 6000 N TRP B 300 0501 39226 48132 1004677 B ATOM 5916 C PRO B 288 -8912 41515 58156 1005608 B ATOM 6001 CA TRP B 300 -0444 38121 48099 1004677 B ATOM 5917 O PRO B 288 -7885 40859 58161 1005608 B ATOM 6002 CB TRP B 300 -1794 38591 47574 1004603 B ATOM 5918 N LYS B 289 9417 42042 57051 1006590 B ATOM 6003 CG TRP B 300 -2804 37514 47553 1004603 B ATOM 5919 CA LYS B 289 -8750 41869 55770 1006590 B ATOM 6004 CD2 TRP B 300 -3278 36763 48677 1004603 B ATOM 5920 CB LYS B 289 -9755 41990 54620 10010030 B ATOM 6005 CE2 TRP B 300 -4222 35836 48190 1004603 B ATOM 5921 CG LYS B 289 -10603 40733 54455 10010030 B ATOM 6006 CE3 TRP B 300 -2996 36785 50047 1004603 B ATOM 5922 CD LYS B 289 -11 604 40860 53326 10010030 B ATOM 6007 CDl TRP B 300 -3458 37029 46465 1004603 B ATOM 5923 CE LYS B 289 -12727 41831 53683 I 0010030 B ATOM 6008 NEl TRP B 300 -4313 36019 46837 1004603 B ATOM 5924 NZ LYS B 289 -13752 41951 52596 10010030 B ATOM 6009 CZ2 TRP B 300 -4890 34937 49026 1004603 B ATOM 5925 C LYS B 289 -7615 42865 55617 1006590 B ATOM 6010 CZ3 TRP B 300 -3658 35893 50880 1004603 B ATOM 5926 O LYS B 289 -7736 43872 54927 1006590 B ATOM 6011 CH2 TRP B 300 -4598 34978 50364 1004603 B ATOM 5927 N VAL B 290 -6502 42550 56273 1005457 B ATOM 6012 C TRP B 300 0047 36977 47231 1004677 B ATOM 5928 CA VAL B 290 -5300 43373 56262 1005457 B ATOM 6013 O TRP B 300 -0092 35808 47612 1004677 B ATOM 5929 CB VAL B 290 -5171 44171 57574 1005201 B ATOM 6014 N LYS B 301 0618 37308 46071 1003679 B ATOM 5930 CGl VAL B 290 -6461 44909 57850 1005201 B ATOM 6015 CA LYS B 301 1 118 36280 45159 1003679 B ATOM 5931 CG2 VAL B 290 -4849 43232 58730 1005201 B ATOM 6016 CB LYS B 301 1733 36911 43904 1009613 B ATOM 5932 C VAL B 290 -4064 42490 56124 1005457 B ATOM 6017 CG LYS B 301 0744 37753 43097 1009613 B ATOM 5933 O VAL B 290 -4138 41266 56269 1005457 B ATOM 6018 CD LYS B 301 -0592 37023 42865 1009613 B ATOM 5934 N GLY B 291 -2928 43 119 55848 1004380 B ATOM 6019 CE LYS B 301 -1699 37991 42452 1009613 B ATOM 5935 CA GLY B 291 -1682 42384 55711 1004380 B ATOM 6020 NZ LYS B 301 -3054 37397 42598 1009613 B ATOM 5936 C GLY B 291 -1712 41 162 54809 1004380 B ATOM 6021 C LYS B 301 2134 35378 45844 1003679 B ATOM 5937 O GLY B 291 -2198 41217 536S4 1004380 B ATOM 6022 O LYS B 301 2171 34174 45584 1003679 B ATOM 5938 N MET B 292 -1 177 40057 55308 1006156 B ATOM 6023 N ASP B 302 2956 35951 46725 1005359 B ATOM 5939 CA MET B 292 -1 111 38812 54558 10061 56 B ATOM 6024 CA ASP B 302 3948 35162 47442 1005359 B ATOM 5940 CB MET B 292 -0201 37829 55277 1006079 B ATOM 6025 CB ASP B 302 4997 36064 48071 1006789 B ATOM 5941 CG MET B 292 -0812 37361 56587 1006079 B ATOM 6026 CG ASP B 302 5927 36665 47041 1006789 B ATOM 5942 SD MET B 292 -0067 35869 57248 1006079 B ATOM 6027 ODl ASP B 302 6445 35902 46207 1006789 B ATOM 5943 CE MET B 292 0627 36472 58729 1006079 B ATOM 6028 OD2 ASP B 302 6149 37892 47064 1006789 B ATOM 5944 C MET B 292 -2479 38158 54415 1006156 B ATOM 6029 C ASP B 302 3275 34304 48502 1005359 B ATOM 5945 O MET B 292 -2591 37085 53818 1006156 B ATOM 6030 O ASP B 302 3680 33168 48745 1005359 B ATOM 5946 N LEU B 293 -3515 38787 54961 1005968 B ATOM 6031 N VAL B 303 2238 34841 49126 1003974 B ATOM 5947 CA LEU B 293 -4846 38206 54899 1005968 B ATOM 6032 CA VAL B 303 1507 34084 50129 1003974 B ATOM 5948 CB LEU B 293 -5559 38425 56231 1004918 B ATOM 6033 CB VAL B 303 0363 34910 50730 1003802 B ATOM 5949 CG LEU B 293 -4922 37725 57430 1004918 B ATOM 6034 CGl VAL B 303 -0488 34037 51655 1002733 B ATOM 5950 CDl LEU B 293 -5628 38142 58707 1004918 B ATOM 6035 CG2 VAL B 303 0943 36101 51495 1002733 B ATOM 5951 CD2 LEU B 293 -5006 36218 57235 1004918 B ATOM 6036 C VAL B 303 0926 32832 49474 1003974 B ATOM 5952 C LEU B 293 -5758 38649 53756 1005968 B ATOM 6037 O VAL B 303 1 125 31715 49961 1003974 B ATOM 5953 O LEU B 293 -6859 38126 53626 1005968 B ATOM 6038 N LYS B 304 0211 33022 48368 I 004365 B ATOM 5954 N THR B 294 -5329 39598 52932 1006738 B ATOM 6039 CA LYS B 304 -0378 31902 47635 1004365 B ATOM 5955 CA THR B 294 -6172 40042 51825 1006738 B ATOM 6040 CB LYS B 304 -0958 32373 46306 1008672 B ATOM 5956 CB THR B 294 -6626 41504 51960 10010347 B ATOM 6041 CG LYS B 304 -2344 32970 46364 1006864 B ATOM 5957 OGl THR B 294 -6944 41788 53322 10010347 B ATOM 6042 CD LYS B 304 -2753 33440 44972 1006864 B ATOM 5958 CG2 THR B 294 -7874 41743 51 103 10010347 B ATOM 6043 CE LYS B 304 -4187 33930 44942 1006864 B ATOM 5959 C THR B 294 -5482 39954 50483 1006738 B ATOM 6044 NZ LYS B 304 -4569 34505 43617 1006864 B ATOM 5960 O THR B 294 -4264 40089 50384 1006738 B ATOM 6045 C LYS B 304 0677 30839 47343 1004365 B ATOM 5961 N VAL B 295 -6279 39750 49441 1005887 B ATOM 6046 O LYS B 304 0460 29640 47541 1004365 B ATOM 5962 CA VAL B 295 5747 39668 48095 1005887 B ATOM 6047 N ALA B 305 1831 31288 46873 1004349 B ATOM 5963 CB VAL B 295 -6835 39223 47117 1007122 B ATOM 6048 CA ALA B 305 2920 30389 46522 1004349 B ATOM 5964 CGl VAL B 295 -6239 39046 45726 1007122 B ATOM 6049 CB ALA B 305 3948 31 141 45724 I 001856 B ATOM 5965 CG2 VAL B 295 -7463 37924 47614 1007122 B ATOM 6050 C ALA B 305 3588 29687 47688 1004349 B ATOM 5966 C VAL B 295 -5248 41053 47713 1005887 B ATOM 6051 O ALA B 305 3751 28471 47670 1004349 B ATOM 5967 O VAL B 295 -4423 41207 46815 1005887 B ATOM 6052 N TYR B 306 3987 30444 48701 1004705 B ATOM 5968 N LYS B 296 -5750 42055 48427 1005574 B ATOM 6053 CA TYR B 306 4647 29847 49859 1004705 B ATOM 5969 CA LYS B 296 -5385 43450 48189 1005574 B ATOM 6054 CB TYR B 306 5340 30921 50691 1005137 B ATOM 5970 CB LYS B 296 -6135 44371 49161 1009295 B ATOM 6055 CG TYR B 306 6491 31575 49982 1004606 B ATOM 5971 CG LYS B 296 -7649 44311 49068 1009295 B ATOM 6056 CDl TYR B 306 6839 32899 50248 1004606 B ATOM 5972 CD LYS B 296 -8170 45006 47823 1009295 B ATOM 6057 CEl TYR B 306 7889 33516 49581 1004606 B ATOM 5973 CE LYS B 296 -7982 46523 47909 1009295 B ATOM 6058 CD2 TYR B 306 7227 30882 49035 1004606 B ATOM 5974 NZ LYS B 296 -8466 47251 46689 1009295 B ATOM 6059 CE2 TYR B 306 8278 31485 48362 1004606 B ATOM 5975 C LYS B 296 -3889 43666 48365 1005574 B ATOM 6060 CZ TYR B 306 8607 32800 48636 1004606 B ATOM 5976 O LYS B 296 -3301 44509 47694 1005574 B ATOM 6061 OH TYR B 306 9656 33388 47968 1004606 B ATOM 5977 N ASN B 297 -3281 42892 49264 1005739 B ATOM 6062 C TYR B 306 3712 29049 50754 1004705 B ATOM 5978 CA ASN B 297 -I 856 43021 49562 1005739 B ATOM 6063 O TYR B 306 3994 27906 51068 1004705 B ATOM 5979 CB ASN B 297 -1463 42097 50716 1006942 B ATOM 6064 N LEU B 307 2605 29649 51 171 1003543 B ATOM 5980 CG ASN B 297 -0065 42388 51242 1006942 B ATOM 6065 CA LEU B 307 1659 28968 52040 1003543 B ATOM 5981 ODl ASN B 297 0926 42269 50522 1006942 B ATOM 6066 CB LEU B 307 0797 29991 52766 1006560 B 65251/C766

ATOM 6067 CG LEU B 307 -0373 29417 53563 1003373 B ATOM 6152 CG2 ILE B 319 4945 13 851 54 828 1 00 23 92 B ATOM 6068 CDl LEU B 307 0122 28471 54650 1003373 B ATOM 6153 CGl ILE B 319 5 573 14 082 57 217 1 00 23 92 B ATOM 6069 CD2 LEU B 307 -1 150 30563 54177 1003373 B ATOM 6154 CDl ILE B 319 4 164 14 019 57 810 1 0023 92 B ATOM 6070 C LEU B 307 0762 28014 51263 1003543 B ATOM 6155 C ILE B 319 7 765 13 527 55 216 1 00 3768 B ATOM 6071 O LEU B 307 0634 26847 51620 1003543 B ATOM 6156 O ILE B 319 8270 12 935 56 160 1 00 3768 B ATOM 6072 N GLY B 308 0133 28517 50205 1003882 B ATOM 6157 N LEU B 320 7 749 13 025 53 986 1 0041 23 B ATOM 6073 CA GLY B 308 -0743 27687 49413 1003882 B ATOM 6158 CA LEU B 320 8 340 11 719 53 698 1 0041 23 B ATOM 6074 C GLY B 308 -0016 26495 48839 1003882 B ATOM 6159 CB LEU B 320 7 889 11 235 52 318 1 00 66 95 B ATOM 6075 O GLY B 308 -0500 25372 48935 1003882 B ATOM 6160 CG LEU B 320 6381 10970 52 170 1 00 44 79 B ATOM 6076 N GLY B 309 1 148 26725 48244 1003732 B ATOM 6161 CDl LEU B 320 6 073 10 480 50 761 1 0044 79 B ATOM 6077 CA GLY B 309 1896 25623 47657 1003732 B ATOM 6162 CD2 LEU B 320 5 934 9 934 53 192 1 00 44 79 B ATOM 6078 C GLY B 309 2259 24514 48634 1003732 B ATOM 6163 C LEU B 320 9 878 11 732 53 793 1 0041 23 B ATOM 6079 O GLY B 309 2057 23323 48361 1003732 B ATOM 6164 O LEU B 320 10490 10 728 54 151 1 0041 23 B ATOM 6080 N PHE B 310 2798 24915 49783 1004311 B ATOM 6165 N ASP B 321 10 501 12 870 53 481 1 0053 93 B ATOM 6081 CA PHE B 310 3212 23986 50816 10043 11 B ATOM 6166 CA ASP B 321 11 943 12 973 53 570 1 00 53 93 B ATOM 6082 CB PHE B 310 3763 24772 51998 1004030 B ATOM 6167 CB ASP B 321 12436 14235 52 872 1 00 9040 B ATOM 6083 CG PHE B 310 4448 23926 53032 1003613 B ATOM 6168 CG ASP B 321 12 308 14 151 51 363 1 00 69 40 B ATOM 6084 CDl PHE B 310 5573 23179 52702 1003613 B ATOM 6169 ODl ASP B 321 12 647 13 088 50 812 1 00 6940 B ATOM 6085 CD2 PHE B 310 3977 23886 54350 1003613 B ATOM 6170 OD2 ASP B 321 11 886 15 151 50 727 1 006940 B ATOM 6086 CEl PHE B 310 6226 22402 53664 I 003613 B ATOM 6171 C ASP B 321 12 335 12 996 55 044 1 00 53 93 B ATOM 6087 CE2 PHE B 310 4627 23110 55323 1003613 B ATOM 6172 O ASP B 321 13 345 12 396 55 434 1 00 53 93 B ATOM 6088 CZ PHE B 310 5751 22369 54974 1003613 B ATOM 6173 N TYR B 322 11 540 13 681 55 866 1 00 56 60 B ATOM 6089 C PHE B 310 2019 23150 51253 1004311 B ATOM 6174 CA TYR B 322 11 831 13 746 57295 1 00 56 60 B ATOM 6090 O PHE B 310 2112 21925 51405 1004311 B ATOM 6175 CB TYR B 322 10 810 14 607 58 039 1 00 42 87 B ATOM 6091 N GLU B 311 0896 23827 51455 1004480 B ATOM 6176 CG TYR B 322 10 977 16 095 57 864 1 0033 58 B ATOM 6092 CA GLU B 311 -0320 23171 51893 1004480 B ATOM 6177 CDl TYR B 322 10 675 16 709 56 655 1 0033 58 B ATOM 6093 CB GLU B 311 -1353 24206 52332 1008004 B ATOM 6178 CEl TYR B 322 10 776 18 091 56494 1 0033 58 B ATOM 6094 CG GLU B 311 -2394 23646 53276 1006427 B ATOM 6179 CD2 TYR B 322 11 397 16 898 58 920 1 0033 58 B ATOM 6095 CD GLU B 311 -3517 24620 53565 1006427 B ATOM 6180 CE2 TYR B 322 11 499 18 274 58 776 1 0033 58 B ATOM 6096 OEl GLU B 311 -3252 25833 53682 1006427 B ATOM 6181 CZ TYR B 322 11 182 18 870 57 555 1 00 33 58 B ATOM 6097 OE2 GLU B 311 -4671 24174 53692 1006427 B ATOM 6182 OH TYR B 322 11 238 20 242 57394 1 0033 58 B ATOM 6098 C GLU B 311 -0909 22314 50790 1004480 B ATOM 6183 C TYR B 322 11 791 12 339 57 870 1 0056 60 B ATOM 6099 O GLU B 311 -1479 21269 51055 1004480 B ATOM 6184 O TYR B 322 12 690 11 914 58 602 1 00 56 60 B ATOM 6100 N TYR B 312 -0770 22753 49548 1003984 B ATOM 6185 N GLN B 323 10732 11 617 57 531 1 0049 55 B ATOM 6101 CA TYR B 312 -1324 21999 48437 1003984 B ATOM 6186 CA GLN B 323 10 563 10 258 58 006 1 0049 55 B ATOM 6102 CB TYR B 312 -1284 22811 47151 1005275 B ATOM 6187 CB GLN B 323 9 337 9 636 57 368 1 00 71 56 B ATOM 6103 CG TYR B 312 -1927 22084 45998 1004745 B ATOM 6188 CG GLN B 323 9098 8 228 57 823 1 0045 95 B ATOM 6104 CDl TYR B 312 -3319 21936 45928 1004745 B ATOM 6189 CD GLN B 323 7 812 7 666 57 283 1 0045 95 B ATOM 6105 CEl TYR B 312 -3925 21232 44876 I 004745 B ATOM 6190 OEl GLN B 323 7 532 7 755 56 075 1 0045 95 B ATOM 6106 CD2 TYR B 312 -1 153 21509 44987 1004745 B ATOM 6191 NE2 GLN B 323 7 014 7 077 58 166 1 00 45 95 B ATOM 6107 CE2 TYR B 312 -1 748 20798 43932 1004745 B ATOM 6192 C GLN B 323 11 786 9397 57 710 1 00 49 55 B ATOM 6108 CZ TYR B 312 -3135 20663 43882 1004745 B ATOM 6193 O GLN B 323 12258 8 670 58 582 1 0049 55 B ATOM 6109 OH TYR B 312 -3736 19966 42850 1004745 B ATOM 6194 N LYS B 324 12 299 9471 56 483 1 00 53 99 B ATOM 6110 C TYR B 312 -0621 20683 48184 1003984 B ATOM 6195 CA LYS B 324 13 484 8 702 56 113 1 00 53 99 B ATOM 6111 O TYR B 312 -1266 19710 47823 1003984 B ATOM 6196 CB LYS B 324 13 911 9 015 54 680 1 0073 94 B ATOM 6112 N MET B 313 0696 20642 48361 1004219 B ATOM 6197 CG LYS B 324 13 089 8 362 53 607 1 0063 37 B ATOM 6113 CA MET B 313 1422 19409 48101 1004219 B ATOM 6198 CD LYS B 324 13 768 8 516 52 251 1 0063 37 B ATOM 6114 CB MET B 313 1525 19182 46594 1006459 B ATOM 6199 CE LYS B 324 12 994 7 800 51 148 1 00 63 37 B ATOM 6115 CG MET B 313 2204 17894 46220 1006444 B ATOM 6200 NZ LYS B 324 13 721 7 813 49 839 1 0063 37 B ATOM 6116 SD MET B 313 2388 17757 44452 1006444 B ATOM 6201 C LYS B 324 14 670 9001 57 032 1 00 53 99 B ATOM 6117 CE MET B 313 0696 17888 43913 1006444 B ATOM 6202 O LYS B 324 15 285 8 092 57 582 1 00 53 99 B ATOM 6118 C MET B 313 2814 19381 48696 1004219 B ATOM 6203 N MET B 325 14995 10 280 57 193 1 004943 B ATOM 6119 O MET B 313 3300 18326 49108 1004219 B ATOM 6204 CA MET B 325 16 129 10 662 58 013 1 0049 43 B ATOM 6120 N GLY B 314 3461 20541 48726 1004213 B ATOM 6205 CB MET B 325 16 519 12 103 57719 1 00 63 99 B ATOM 6121 CA GLY B 314 4809 20622 49253 1004213 B ATOM 6206 CG MET B 325 16 977 12 305 56312 1 00 52 55 B ATOM 6122 C GLY B 314 5028 19852 50536 1004213 B ATOM 6207 SD MET B 325 17403 13 991 55 996 1 00 52 55 B ATOM 6123 O GLY B 314 5912 18990 50627 1004213 B ATOM 6208 CE MET B 325 15 957 14 576 55 191 1 00 52 55 B ATOM 6124 N CYS B 315 4216 20167 51536 1004613 B ATOM 6209 C MET B 325 15 888 10 494 59495 1 0049 43 B ATOM 6125 CA CYS B 315 4342 19516 52820 1004613 B ATOM 6210 O MET B 325 16 828 10 519 60 291 1 004943 B ATOM 6126 CB CYS B 315 3303 20076 53777 1005637 B ATOM 6211 N ALA B 326 14 636 10 317 59 882 1 0049 61 B ATOM 6127 SG CYS B 315 3661 19641 55475 1006174 B ATOM 6212 CA ALA B 326 14 335 10 157 61 301 1 0049 61 B ATOM 6128 C CYS B 315 4226 17986 52753 1004613 B ATOM 6213 CB ALA B 326 12 972 10 812 61 641 1 00 29 77 B ATOM 6129 O CYS B 315 5106 17270 53245 1004613 B ATOM 6214 C ALA B 326 14 323 8 694 61 722 1 0049 61 B ATOM 6130 N SER B 316 3147 17482 52154 1004391 B ATOM 6215 O ALA B 326 14 596 8 383 62 875 1 0049 61 B ATOM 6131 CA SER B 316 2952 16035 52046 1004391 B ATOM 6216 N LYS B 327 14 021 7 811 60 772 1 00 7493 B ATOM 6132 CB SER B 316 1 707 15722 51230 1004687 B ATOM 6217 CA LYS B 327 13 917 6 382 61 030 1 00 74 93 B ATOM 6133 OG SER B 316 1893 16081 49876 1005237 B ATOM 6218 CB LYS B 327 14427 5 569 59 841 1 00153 80 B ATOM 6134 C SER B 316 4145 15316 51413 1004391 B ATOM 6219 CG LYS B 327 14025 4 106 59 946 1 0072 09 B ATOM 6135 O SER B 316 4381 14144 51 696 1004391 B ATOM 6220 CD LYS B 327 14407 3 309 58 712 1 0072 09 B ATOM 6136 N LEU B 317 4880 16001 50537 1004003 B ATOM 6221 CE LYS B 327 13 906 1 863 58 806 1 00 72 09 B ATOM 6137 CA LEU B 317 6056 15408 49920 1004003 B ATOM 6222 NZ LYS B 327 14300 1 051 57615 1 00 72 09 B ATOM 6138 CB LEU B 317 6402 16142 48630 1004423 B ATOM 6223 C LYS B 327 14 587 5 875 62 302 1 007493 B ATOM 6139 CG LEU B 317 5427 15943 47469 1003674 B ATOM 6224 O LYS B 327 13 912 5 453 63 243 1 00 7493 B ATOM 6140 CDl LEU B 317 5796 16853 46303 1003674 B ATOM 6225 N GLY B 328 15 906 5 918 62 362 1 00 48 57 B ATOM 6141 CD2 LEU B 317 5453 14487 47040 1003674 B ATOM 6226 CA GLY B 328 16 539 5 406 63 561 1 0048 57 B ATOM 6142 C LEU B 317 7240 15495 50895 1004003 B ATOM 6227 C GLY B 328 16 747 6 345 64 745 1 00 48 57 B ATOM 6143 O LEU B 317 7986 14538 51084 1004003 B ATOM 6228 O GLY B 328 16 841 5 879 65 880 I 0048 57 B ATOM 6144 N ALA B 318 7393 16645 51535 1003743 B ATOM 6229 N LYS B 329 16 798 7 659 64 504 1 00 61 07 B ATOM 6145 CA ALA B 318 8490 16851 52461 1003743 B ATOM 6230 CA LYS B 329 17061 8 600 65 575 1 00 61 07 B ATOM 6146 CB ALA B 318 8484 18293 52949 I 003740 B ATOM 6231 CB LYS B 329 17 884 9 764 65 020 1 0019058 B ATOM 6147 C ALA B 318 8439 15899 53647 1003743 B ATOM 6232 CG LYS B 329 19267 9350 64542 1 0019058 B ATOM 6148 O ALA B 318 9451 15288 54013 1003743 B ATOM 6233 CD LYS B 329 20 178 10 556 64 440 1 00190 58 B ATOM 6149 N ILE B 319 7263 15771 54253 1003768 B ATOM 6234 CE LYS B 329 21 600 10 179 64063 1 00 80 34 B ATOM 6150 CA ILE B 319 7127 14903 55417 1003768 B ATOM 6235 NZ LYS B 329 22 466 11 401 64 021 1 00 80 34 B ATOM 6151 CB ILE B 319 5650 14720 55822 I 004936 B ATOM 6236 C LYS B 329 15 935 9 147 66 448 1 0061 07 B 65251/C766

ATOM 6237 O LYS B 329 16144 10137 67134 1006107 B ATOM 6322 CA THR B 341 -16204 2746 78707 1008107 B ATOM 6238 N ILE B 330 14754 8538 66456 1004824 B ATOM 6323 CB THR B 341 -15474 3230 79969 10010104 B ATOM 6239 CA ILE B 330 13682 9049 67325 1004824 B ATOM 6324 OGl THR B 341 -14275 2468 80143 1008240 B ATOM 6240 CB ILE B 330 12668 9957 66557 1004126 B ATOM 6325 CG2 THR B 341 -16359 3057 81 198 1008240 B ATOM 6241 CG2 ILE B 330 13404 11 102 65864 1004218 B ATOM 6326 C THR B 341 -17521 3497 78589 008322 B ATOM 6242 CGl ILE B 330 11871 9134 65539 1004218 B ATOM 6327 O THR B 341 -17583 4583 78014 008482 B ATOM 6243 CDl ILE B 330 10647 9828 65047 1004218 B ATOM 6328 N GLY B 342 -18572 2913 79150 0014783 B ATOM 6244 C ILE B 330 12918 7895 67962 1004824 B ATOM 6329 CA GLY B 342 -19873 3546 79094 10015200 B ATOM 6245 O ILE B 330 13102 6747 67566 1004824 B ATOM 6330 C GLY B 342 -20324 4094 80432 10015097 B ATOM 6246 N PRO B 331 12047 8177 68955 1004899 B ATOM 6331 O GLY B 342 -21305 3615 81000 10014524 B ATOM 6247 CD PRO B 331 11670 9497 69477 1004027 B ATOM 6332 N ASN B 343 -19609 5092 80942 1008750 B ATOM 6248 CA PRO B 331 11264 7133 69630 1004899 B ATOM 6333 CA ASN B 343 -19963 5714 82216 1009391 B ATOM 6249 CB PRO B 331 10191 7925 70354 10018425 B ATOM 6334 CB ASN B 343 -18874 6688 82661 10017687 B ATOM 6250 CG PRO B 331 10907 9116 70733 1004027 B ATOM 6335 CG ASN B 343 -17499 6058 82681 10015667 B ATOM 6251 C PRO B 331 10663 6156 68635 1004899 B ATOM 6336 ODl ASN B 343 -17246 5109 83423 10015667 B ATOM 6252 O PRO B 331 10129 6564 67602 1004899 B ATOM 6337 ND2 ASN B 343 -16598 6587 81861 10015667 B ATOM 6253 N LYS B 332 10761 4868 68944 1005271 B ATOM 6338 C ASN B 343 21259 6486 82014 1009197 B ATOM 6254 CA LYS B 332 10214 3829 68081 1005333 B ATOM 6339 O ASN B 343 -21932 6303 81007 1008060 B ATOM 6255 CB LYS B 332 10725 2463 68521 10012091 B ATOM 6340 N GLU B 344 -21605 7348 82966 10016821 B ATOM 6256 CG LYS B 332 10311 2117 69930 1009245 B ATOM 6341 CA GLU B 344 -22818 8156 82860 10016821 B ATOM 6257 CD LYS B 332 10396 0627 70183 1009245 B ATOM 6342 CB GLU B 344 -24058 7299 83143 10020010 B ATOM 6258 CE LYS B 332 9775 0269 71524 1009245 B ATOM 6343 CG GLU B 344 -24604 6633 81881 10018000 B ATOM 6259 NZ LYS B 332 9750 -1200 71738 1009245 B ATOM 6344 CD GLU B 344 -25718 5643 82148 10018000 B ATOM 6260 C LYS B 332 8692 3842 68170 1005240 B ATOM 6345 OEl GLU B 344 -25429 4538 82651 10018000 B ATOM 6261 O LYS B 332 8123 4328 69152 1005049 B ATOM 6346 OE2 GLU B 344 -26886 5971 81855 10018000 B ATOM 6262 N ASP B 333 8033 3316 67140 1005499 B ATOM 6347 C GLU B 344 -22757 9367 83785 10016821 B ATOM 6263 CA ASP B 333 6573 3247 67127 1005445 B ATOM 6348 O GLU B 344 -22844 9245 85006 10016821 B ATOM 6264 CB ASP B 333 6080 2668 65800 10014791 B ATOM 6349 N LEU B 345 -22608 10538 83170 10020084 B ATOM 6265 CG ASP B 333 5855 3732 64748 10011550 B ATOM 6350 CA LEU B 345 -22481 11806 83882 10020084 B ATOM 6266 ODl ASP B 333 6648 4696 64696 10011550 B ATOM 6351 CB LEU B 345 -21903 12869 82934 10015136 B ATOM 6267 OD2 ASP B 333 4890 3601 63965 10011550 B ATOM 6352 CG LEU B 345 -20510 12605 82337 10010415 B ATOM 6268 C ASP B 333 6099 2366 68278 1005830 B ATOM 6353 CDl LEU B 345 -20080 13787 81477 10010415 B ATOM 6269 O ASP B 333 6717 1355 68602 1005795 B ATOM 6354 CD2 LEU B 345 -19497 12381 83447 10010415 B ATOM 6270 N THR B 334 5003 2763 68903 1005293 B ATOM 6355 C LEU B 345 -23723 12363 84591 10020084 B ATOM 6271 CA THR B 334 4468 1999 70010 1005265 B ATOM 6356 O LEU B 345 -23913 13578 84660 10020084 B ATOM 6272 CB THR B 334 4867 2635 71348 1007363 B ATOM 6357 N GLU B 346 24560 11471 85112 10020084 ATOM 6273 OGl THR B 334 6251 2357 71598 1005953 B ATOM 6358 CA GLU B 346 -25757 11842 85873 10020084 ATOM 6274 CG2 THR B 334 4021 2090 72483 1005953 B ATOM 6359 CB GLU B 346 -25327 12611 87124 10016829 ATOM 6275 C THR B 334 2958 1912 69912 1005909 B ATOM 6360 CG GLU B 346 -24112 11985 87793 10015372 B ATOM 6276 O THR B 334 2262 2934 69916 1005645 B ATOM 6361 CD GLU B 346 -23943 12399 89236 10015372 B ATOM 6277 N THR B 335 2458 0681 69825 1004432 B ATOM 6362 OEl GLU B 346 -24806 12029 90061 10015372 B ATOM 6278 CA THR B 335 1021 0438 69716 1004411 B ATOM 6363 OE2 GLU B 346 -22948 13091 89543 10015372 B ATOM 6279 CB THR B 335 0750 -0965 69222 1005794 B ATOM 6364 C GLU B 346 -26910 12585 85186 10020084 B ATOM 6280 OGl THR B 335 1603 -1251 68106 1004730 B ATOM 6365 O GLU B 346 -27958 11989 84928 10020084 B ATOM 6281 CG2 THR B 335 -0691 -1082 68796 1004730 B ATOM 6366 N ASP B 347 -26741 13876 84905 10020084 B ATOM 6282 C THR B 335 0278 0630 71027 1004497 B ATOM 6367 CA ASP B 347 -27813 14647 84273 10020084 B ATOM 6283 O THR B 335 0673 0115 72062 1004632 B ATOM 6368 CB ASP B 347 -27425 16128 84153 10019676 B ATOM 6284 N PRO B 336 0834 1357 70991 1005780 B ATOM 6369 CG ASP B 347 -26568 16416 82933 10019676 B ATOM 6285 CD PRO B 336 -1464 1 994 69823 1004282 B ATOM 6370 ODl ASP B 347 -25456 15857 82839 10019676 B ATOM 6286 CA PRO B 336 -1612 1608 72200 1005738 B ATOM 6371 OD2 ASP B 347 -27007 17204 82066 10019676 B ATOM 6287 CB PRO B 336 2375 2862 71840 1005168 B ATOM 6372 C ASP B 347 -28194 14100 82897 10020084 B ATOM 6288 CG PRO B 336 -2763 2549 70411 1004282 B ATOM 6373 O ASP B 347 -29371 14094 82531 10020084 B ATOM 6289 C PRO B 336 -2562 0479 72598 1005742 B ATOM 6374 N GLY B 348 -27198 13642 82142 10015614 B ATOM 6290 O PRO B 336 -2719 -0525 71894 1005805 B ATOM 6375 CA GLY B 348 -27456 13096 80821 10015345 B ATOM 6291 N THR B 337 -3189 0681 73749 1006294 B ATOM 6376 C GLY B 348 -27524 U 583 80854 10015041 B ATOM 6292 CA THR B 337 -4165 -0227 74304 1006640 B ATOM 6377 O GLY B 348 -26841 10952 81660 10014542 B ATOM 6293 CB THR B 337 -3812 -0570 75745 10013109 B ATOM 6378 N ASN B 349 -28338 10997 79979 10020084 B ATOM 6294 OGl THR B 337 -2675 -1432 75747 1008198 B ATOM 6379 CA ASN B 349 28486 9548 79944 10020084 B ATOM 6295 CG2 THR B 337 -4975 -1241 76446 1008198 B ATOM 6380 CB ASN B 349 -29342 9124 78739 10019627 B ATOM 6296 C THR B 337 -5447 0588 74290 1007397 B ATOM 6381 CG ASN B 349 -29118 9995 77517 10018145 B ATOM 6297 O THR B 337 -5454 1744 74715 1006535 B ATOM 6382 ODl ASN B 349 -29374 11200 77540 10018145 B ATOM 6298 N VAL B 338 -6531 0012 73790 1005788 B ATOM 6383 ND2 ASN B 349 -28645 9385 76439 10018145 B ATOM 6299 CA VAL B 338 -7779 0758 73753 1006474 B ATOM 6384 C ASN B 349 -27162 8778 79967 10020084 B ATOM 6300 CB VAL B 338 -8266 0977 72295 1008093 B ATOM 6385 O ASN B 349 -26713 8362 81034 10020084 B ATOM 6301 CGl VAL B 338 -9421 1983 72275 1008055 B ATOM 6386 N MET B 350 -26526 8603 78813 10016136 B ATOM 6302 CG2 VAL B 338 -7118 1460 71427 I 008055 B ATOM 6387 CA MET B 350 -25272 7851 78758 10015745 B ATOM 6303 C VAL B 338 8879 0065 74546 1006921 B ATOM 6388 CB MET B 350 -25485 6578 77928 10020084 B ATOM 6304 O VAL B 338 -8928 -1 162 74635 1006904 B ATOM 6389 CG MET B 350 -24255 5698 77781 10016592 B ATOM 6305 N LYS B 339 -9758 0875 75123 1005043 B ATOM 6390 SD MET B 350 -24603 4149 76920 10016592 B ATOM 6306 CA LYS B 339 -10878 0397 75912 1004831 B ATOM 6391 CE MET B 350 -24674 3002 78299 10016592 B ATOM 6307 CB LYS B 339 -10439 0170 77360 10014202 B ATOM 6392 C MET B 350 -24067 8629 78216 10015459 B ATOM 6308 CG LYS B 339 -9407 -0932 77516 10011033 B ATOM 6393 O MET B 350 -24217 9608 77487 10015102 B ATOM 6309 CD LYS B 339 -8448 -0660 78669 10011033 B ATOM 6394 N THR B 351 -22871 8179 78590 10010528 B ATOM 6310 CE LYS B 339 -7331 -1697 78709 10011033 B ATOM 6395 CA THR B 351 21625 8800 78141 10010324 B ATOM 6311 NZ LYS B 339 -6267 -1344 79690 10011033 B ATOM 6396 CB THR B 351 -20999 9687 79252 10011268 B ATOM 6312 C LYS B 339 -11925 1491 75853 1005730 B ATOM 6397 OGl THR B 351 -20324 10796 78652 1007980 B ATOM 6313 O LYS B 339 -11615 2668 76042 1004996 B ATOM 6398 CG2 THR B 351 -19972 8907 80065 1007980 B ATOM 6314 N VAL B 340 -13162 1 111 75569 1008419 B ATOM 6399 C THR B 351 -20605 7727 77735 1009747 B ATOM 6315 CA VAL B 340 -14245 2085 75508 1008162 B ATOM 6400 O THR B 351 -20411 6733 78443 1008906 B ATOM 6316 CB VAL B 340 -15105 1898 74251 1005849 B ATOM 6401 N LEU B 352 -19961 7925 76590 1008885 B ATOM 6317 CGl VAL B 340 -16219 2929 74235 1004395 B ATOM 6402 CA LEU B 352 -18962 6975 76121 1009187 B ATOM 6318 CG2 VAL B 340 -14248 2021 73010 1004395 B ATOM 6403 CB LEU B 352 -19281 6528 74695 1009405 B ATOM 6319 C VAL B 340 15137 1866 76720 1008419 B ATOM 6404 CG LEU B 352 -20369 5455 74658 1007511 B ATOM 6320 O VAL B 340 -15619 0765 76921 1008104 B ATOM 6405 CDl LEU B 352 -20858 5242 73235 1007511 B ATOM 6321 N THR B 341 -15364 2900 77525 1008517 B ATOM 6406 CD2 LEU B 352 -19813 4169 75244 1007511 B 65251/C766

ATOM 6407 C LEU B 352 -17566 7 572 76 194 00 88 55 B ATOM 6492 CG ASP B 363 0516 11410 64433 1006877 B ATOM 6408 O LEU B 352 -17345 8 731 75 834 00 84 17 B ATOM 6493 ODl ASP B 363 1630 11202 64959 1006877 B ATOM 6409 N GLU B 353 -16 628 6 767 76 676 1 00 82 35 B ATOM 6494 OD2 ASP B 363 0165 10848 63369 1006877 B ATOM 6410 CA GLU B 353 -15 258 7209 76 824 1 00 78 60 B ATOM 6495 C ASP B 363 -1781 10867 66596 1004326 B ATOM 6411 CB GLU B 353 -14 929 7371 78 302 1 00200 84 B ATOM 6496 O ASP B 363 -1447 9728 66255 1003976 B ATOM 6412 CG GLU B 353 -13 532 7 872 78 565 1 00168 91 B ATOM 6497 N VAL B 364 -2992 11 154 67055 1004790 B ATOM 6413 CD GLU B 353 13 225 7928 80 038 1 00168 91 B ATOM 6498 CA VAL B 364 -4035 10148 67127 1005022 B ATOM 6414 OEl GLU B 353 -13 97 > 8 609 80 772 1 00168 91 B ATOM 6499 CB VAL B 364 -4149 9519 68525 1007365 B ATOM 6415 OE2 GLU B 353 12 239 7290 80462 1 00168 91 B ATOM 6500 CGl VAL B 364 -5507 8887 68705 1005204 B ATOM 6416 C GLU B 353 -14276 6 237 76 186 1 00 81 85 B ATOM 6501 CG2 VAL B 364 -3111 8449 68686 1005204 B ATOM 6417 O GLU B 353 -14 133 5 093 76 625 1 00 82 63 B ATOM 6502 C VAL B 364 -5332 10835 66807 1005756 B ATOM 6418 N CYS B 354 -13 601 6 711 75 143 00 82 50 B ATOM 6503 O VAL B 364 -5551 11972 67210 1004930 B ATOM 6419 CA CYS B 354 -12 616 5 921 74 422 1 00 82 78 B ATOM 6504 N ILE B 365 -6183 10156 66055 1005418 B ATOM 6420 C CYS B 354 -11 265 6 337 74970 00 83 87 B ATOM 6505 CA ILE B 365 -7470 10718 65716 1004823 B ATOM 6421 O CYS B 354 -10921 7 517 74 929 00 82 57 B ATOM 6506 CB ILE B 365 -7535 11 168 64256 1006779 B ATOM 6422 CB CYS B 354 -12 684 6249 72 932 1 00116 09 B ATOM 6507 CG2 ILE B 365 -8954 11 575 63892 1004423 B ATOM 6423 SG CYS B 354 -11 841 5 084 71 810 1 00 93 28 B ATOM 6508 CGl ILE B 365 -6583 12347 64069 1004423 B ATOM 6424 N THR B 355 -10506 5 391 75 510 1 00 53 31 B ATOM 6509 CDl ILE B 365 -6600 12957 62679 1004423 B ATOM 6425 CA THR B 355 -9 194 5 742 76 031 1 00 42 67 B ATOM 6510 C ILE B 365 -8509 9671 66008 1005499 B ATOM 6426 CB THR B 355 -9080 5 537 77 554 1 0092 36 B ATOM 6511 O ILE B 365 -8277 8476 65847 1005576 B ATOM 6427 OGl THR B 355 -8 38C 4320 77 808 1 00 41 51 B ATOM 6512 N THR B 366 -9661 10147 66451 1004772 B ATOM 6428 CG2 THR B 355 -1045 ! 5 483 78208 1 0041 51 B ATOM 6513 CA THR B 366 -10754 9292 66840 1005600 B ATOM 6429 C THR B 355 -8 118 4 918 75 344 1 00 56 16 B ATOM 6514 CB THR B 366 -10929 9415 68357 1005857 B ATOM 6430 O THR B 355 -8 186 3 685 75 292 1 00 48 96 B ATOM 6515 OGl THR B 366 -10805 8125 68952 1004625 B ATOM 6431 N VAL B 356 -7 127 5 621 74 807 1 00 62 23 B ATOM 6516 CG2 THR B 366 -12253 10037 68709 1004625 B ATOM 6432 CA VAL B 356 -6 023 4 991 74 098 1 00 5795 B ATOM 6517 C THR B 366 -12046 9651 66130 1006498 B ATOM 6433 CB VAL B 356 -5 835 5 666 72 723 1 00 64 17 B ATOM 6518 O THR B 366 -12392 10823 66007 1006422 B ATOM 6434 CGl VAL B 356 4 86S 4 878 71 865 1 00 48 70 B ATOM 6519 N LYS B 367 -12748 8628 65660 1005900 B ATOM 6435 CG2 VAL B 356 -7 18' 5 772 72 029 1 00 48 70 B ATOM 6520 CA LYS B 367 -14033 8810 64988 1006220 B ATOM 6436 C VAL B 356 -4 794 5 157 74 970 I 00 66 79 B ATOM 6521 CB LYS B 367 -13961 8402 63515 I 007141 B ATOM 6437 O VAL B 356 -4 404 6274 75 302 1 00 67 90 B ATOM 6522 CG LYS B 367 -13187 9363 62654 1006242 B ATOM 6438 N ASN B 357 -4 186 4036 75 334 1 00 51 54 B ATOM 6523 CD LYS B 367 -13349 9070 61 178 1006242 B ATOM 6439 CA ASN B 357 -3 036 4 052 76 227 1 004776 B ATOM 6524 CE LYS B 367 -12743 IQ 200 60360 1006242 B ATOM 6440 CB ASN B 357 -3 245 3 057 77 362 1 00130 73 B ATOM 6525 NZ LYS B 367 -13138 10144 58928 1006242 B ATOM 6441 CG ASN B 357 -4413 3 427 78 234 1 00 84 65 B ATOM 6526 C LYS B 367 -15097 7970 65671 1006490 B ATOM 6442 ODl ASN B 357 -4491 4544 78 744 1 00 84 65 B ATOM 6527 O LYS B 367 -14889 6780 65922 1006521 B ATOM 6443 ND2 ASN B 357 -5 33" 2492 78 409 1 00 84 65 B ATOM 6528 N TRP B 368 -16226 8599 65983 1006777 B ATOM 6444 C ASN B 357 -1 666 3 832 75 654 1 00 51 92 B ATOM 6529 CA TRP B 368 17342 7904 66610 1006783 B ATOM 6445 O ASN B 357 -1 404 2 836 74 973 1 00 54 80 B ATOM 6530 CB TRP B 368 -17933 8740 67742 1008409 B ATOM 6446 N SER B 358 -0 793 4 778 75 998 1 00 55 92 B ATOM 6531 CG TRP B 368 -17040 8825 68917 1006401 B ATOM 6447 CA SER B 358 0605 4 822 75 589 00 63 22 B ATOM 6532 CD2 TRP B 368 -16950 7882 69990 006401 B ATOM 644S CB SER B 358 1 475 4093 76 621 00 55 35 B ATOM 6533 CE2 TRP B 368 -15935 8333 70859 006401 B ATOM 6449 OG SER B 358 1 231 2 711 76 574 1 00 53 69 B ATOM 6534 CE3 TRP B 368 -17628 6696 70302 006401 B ATOM 6450 C SER B 358 0929 4 327 74 172 1 00 6794 B ATOM 6535 CDl TRP B 368 -16107 9783 69170 006401 B ATOM 6451 O SER B 358 1 240 3 152 73 953 1 0063 49 B ATOM 6536 NEl TRP B 368 -15436 9496 70337 006401 B ATOM 6452 N PHE B 359 0 866 5 271 73 232 1 00 4400 B ATOM 6537 CZ2 TRP B 368 -15582 7541 72019 I 006401 B ATOM 6453 CA PHE B 359 1 154 5 060 71 805 1 0038 31 B ATOM 6538 CZ3 TRP B 368 -17275 6008 71455 1006401 B ATOM 6454 CB PHE B 359 -0094 5 401 70 991 1 0040 69 B ATOM 6539 CH2 TRP B 368 -16262 6482 72299 1006401 B ATOM 6455 CG PHE B 359 0754 6 699 71 394 1 0035 29 B ATOM 6540 C TRP B 368 -18399 7651 65544 1006978 B ATOM 6456 CDl PHE B 359 0296 7 911 70 903 1 00 35 29 B ATOM 6541 O TRP B 368 -18962 8590 64975 1006997 B ATOM 6457 CD2 PHE B 359 -1 860 6 697 72 243 1 00 35 29 B ATOM 6542 N ILE B 369 -18663 6376 65280 1007752 B ATOM 6458 CEl PHE B 359 -0926 9 100 71 243 1 0035 29 B ATOM 6543 CA ILE B 369 -19632 5994 64264 1007889 B ATOM 6459 CE2 PHE B 359 2 503 7 884 72 592 1 0035 29 B ATOM 6544 CB ILE B 369 -18915 5316 63084 1008697 B ATOM 6460 CZ PHE B 359 -2 036 9 085 72 090 1 0035 29 B ATOM 6545 CG2 ILE B 369 -19906 5009 61981 1006465 B ATOM 6461 C PHE B 359 2 298 6 011 71 445 1 004490 B ATOM 6546 CGl ILE B 369 -17803 6230 62567 1006465 B ATOM 6462 O PHE B 359 2 349 7 104 72 007 1 004245 B ATOM 6547 CDl ILE B 369 -16924 5594 61533 1006465 B ATOM 6463 N TYR B 360 3 216 5 651 70 546 1 00127 29 B ATOM 6548 C ILE B 369 20674 5031 64821 1008071 B ATOM 6464 CA TYR B 360 4258 6 637 70305 1 0012707 B ATOM 6549 O ILE B 369 -20329 4085 65531 1007751 B ATOM 6465 CB TYR B 360 5 596 6 088 69 824 1 0015652 B ATOM 6550 N GLU B 370 -21944 5274 64507 1005964 B ATOM 6466 CG TYR B 360 6450 7292 69427 1 0043 66 B ATOM 6551 CA GLU B 370 23010 4391 64966 1006229 B ATOM 6467 CDl TYR B 360 6 535 8 416 70 270 1 00 43 66 B ATOM 6552 CB GLU B 370 -24357 4920 64483 10011577 B ATOM 6468 CEl TYR B 360 7 172 9 599 69 860 1 0043 66 B ATOM 6553 CG GLU B 370 -24815 6113 65300 1009441 B ATOM 6469 CD2 TYR B 360 7046 7 383 68 163 1 0043 66 B ATOM 6554 CD GLU B 370 -26010 6821 64708 1009441 ATOM 6470 CE2 TYR B 360 7 697 8 564 67 749 1 0043 66 B ATOM 6555 OEl GLU B 370 -26990 6136 64340 1009441 B ATOM 6471 CZ TYR B 360 7747 9 659 68 603 I 00 43 66 B ATOM 6556 OE2 GLU B 370 -25974 8067 64623 1009441 B ATOM 6472 OH TYR B 360 8367 10 806 68 200 1 00 43 66 B ATOM 6557 C GLU B 370 -22739 2984 64436 1006247 B ATOM 6473 C TYR B 360 3 957 7 805 69403 1 00128 16 B ATOM 6558 O GLU B 370 -22460 2804 63254 1006132 B ATOM 6474 O TYR B 360 3 669 8 884 69 902 1 00134 09 B ATOM 6559 N SER B 371 -22812 1991 65317 1007668 B ATOM 6475 N PRO B 361 4 064 7 633 68 072 1 00 6906 B ATOM 6560 CA SER B 371 -22530 0604 64948 1007722 B ATOM 6476 CD PRO B 361 3 906 6412 67257 1 0040 46 B ATOM 6561 CB SER B 371 -22675 -0295 66175 10011366 B ATOM 6477 CA PRO B 361 3 757 8 860 67313 1 00 64 65 B ATOM 6562 OG SER B 371 -23979 -0193 66712 10010274 B ATOM 6478 CB PRO B 361 3 553 8 360 65 880 1 00 39 70 B ATOM 6563 C SER B 371 -23350 0016 63794 1007649 B ATOM 6479 CG PRO B 361 3 115 6928 66053 1 0040 46 B ATOM 6564 O SER B 371 -22912 -0948 63 152 1007743 B ATOM 6480 C PRO B 361 2525 9474 67984 1 007205 B ATOM 6565 N GLU B 372 -24533 0573 63538 1006740 B ATOM 6481 O PRO B 361 1 443 8 901 67 982 1 00 6922 B ATOM 6566 CA GLU B 372 -25366 0074 62456 1006595 B ATOM 6482 N PRO B 362 2 711 10 630 68 631 0042 48 B ATOM 6567 CB GLU B 372 26623 0930 62312 10011602 B ATOM 6483 CD PRO B 362 3 969 11 394 68 584 1 0051 93 B ATOM 6568 CG GLU B 372 -26339 2396 62066 10011602 B ATOM 6484 CA PRO B 362 1 683 11 372 69 358 1 0036 19 B ATOM 6569 CD GLU B 372 -27565 3 161 61599 10011602 B ATOM 6485 CB PRO B 362 2 452 12 577 69 904 1 00 51 93 B ATOM 6570 OEl GLU B 372 -28091 2832 60513 10011602 B ATOM 6486 CG PRO B 362 3 510 12 781 68 910 1 00 51 93 B ATOM 6571 OE2 GLU B 372 -28003 4090 62315 10011602 B ATOM 6487 C PRO B 362 0398 1 756 68 652 0038 79 B ATOM 6572 C GLU B 372 -24578 0091 61 141 1007056 B ATOM 6488 O PRO B 362 -0 589 12 110 69 311 1 0043 55 B ATOM 6573 O GLU B 372 -24665 -0843 60334 1007163 B ATOM 6489 N ASP B 363 0401 1 694 67 324 00 39 87 B ATOM 6574 N HIS B 373 -23794 1 147 60946 1007484 B ATOM 6490 CA ASP B 363 -0 794 12 031 66 557 1 00 39 72 B ATOM 6575 CA HIS B 373 -23006 1315 59737 1007833 B ATOM 6491 CB ASP B 363 0440 12 403 65 100 1 00 7456 B ATOM 6576 CB HIS B 373 -22368 2694 59730 10010196 B 65251/C766

ATOM 6577 CG HIS B 373 -23363 3806 59735 1007131 B ATOM 6662 ND2 ASN B 382 -7152 2730 52631 1004047 B ATOM 0578 CD2 HIS B 373 -23522 4859 60571 1007131 B ATOM 6663 C ASN B 382 -11529 3246 52853 1006253 B ATOM 6579 NDl HIS B 373 -24355 3917 58786 1007131 B ATOM 6664 O ASN B 382 -12002 4272 53362 1006253 B ATOM 6580 CEl HIS B 373 -25081 4992 59035 1007131 B ATOM 6665 N GLY B 383 -11751 2925 51586 1003225 B ATOM 6581 NE2 HIS B 373 -24597 5583 60113 1007131 B ATOM 6666 CA GLY B 383 -12546 3849 50788 1003225 B ATOM 6582 C HIS B 373 ■■21940 0266 59492 1007410 B ATOM 6667 C GLY B 383 -14038 3976 51059 1003225 B ATOM 6583 O HIS B 373 21334 0246 58424 1006994 B ATOM 6668 O GLY B 383 -14720 4712 50354 1003225 B ATOM 6584 N PHE B 374 -21695 -0608 60459 1006801 B ATOM 6669 N ARG B 384 -14557 3278 52063 1005348 B ATOM 6585 CA PHE B 374 -20689 -1637 60249 1006878 B ATOM 6670 CA ARG B 384 -15988 3320 52339 1005348 B ATOM 6586 CB PHE B 374 -19813 -1817 61484 1008600 B ATOM 6671 CB ARG B 384 -16384 2120 53194 1005295 B ATOM 6587 CG PHE B 374 -18865 -0692 61698 1006618 B ATOM 6672 CG ARG B 384 -17881 1948 53376 1005295 B ATOM 6588 CDl PHE B 374 -19292 0491 62303 1006618 B ATOM 6673 CD ARG B 384 -18183 0549 53887 1005295 B ATOM 6589 CD2 PHE B 374 -17562 -0778 61225 1006618 B ATOM 6674 NE ARG B 384 -17688 -0461 52957 1005295 B ATOM 6590 CEl PHE B 374 -18435 1576 62426 1006618 B ATOM 6675 CZ ARG B 384 17612 1762 53220 1005295 B ATOM 6591 CE2 PHE B 374 -16692 0300 61340 100661S B ATOM 6676 NHl ARG B 384 -17998 -2246 54394 1005295 B ATOM 6592 CZ PHE B 374 -17129 1482 61942 1006618 B ATOM 6677 NH2 ARG B 384 -17137 -2585 52300 1005295 B ATOM 6593 C PHE B 374 -21314 -2957 59861 1006486 B ATOM 6678 C ARG B 384 16438 4595 53015 1005348 B ATOM 6594 O PHE B 374 -20631 -3989 59836 1006310 B ATOM 6679 O ARG B 384 -15683 5212 53755 1005348 B ATOM 6595 N LYS B 375 -22610 -2909 59546 1009194 B ATOM 6680 N TYR B 385 -17676 4988 52748 1005957 B ATOM 6596 CA LYS B 375 -23379 -4082 59131 1009457 B ATOM 6681 CA TYR B 385 -18237 6186 53351 1005957 B ATOM 6597 CB LYS B 375 -23474 -4139 57598 10011762 B ATOM 6682 CB TYR B 385 -19312 6771 52446 1007484 B ATOM 6598 CG LYS B 375 -24526 -3225 56962 1009146 B ATOM 6683 CG TYR B 385 -20065 7891 53103 1007484 B ATOM 6599 CD LYS B 375 -24165 1748 57045 1009146 B ATOM 6684 CDl TYR B 385 -19488 9150 53256 1007484 B ATOM 6600 CE LYS B 375 -25200 -0887 56320 1009146 B ATOM 6685 CEl TYR B 385 -20145 10163 53941 1007484 B ATOM 6601 NZ LYS B 375 -24923 0573 56441 1009146 B ATOM 6686 CD2 TYR B 385 -21326 7675 53646 1007484 B ATOM 6602 C LYS B 375 22826 5412 59643 1009959 B ATOM 6687 CE2 TYR B 385 -21993 8680 54335 1007484 B ATOM 6603 O LYS B 375 -22551 -6318 58856 10010185 B ATOM 6688 CZ TYR B 385 -21396 9920 54481 1007484 B ATOM 6604 N GLY B 376 -22650 -5527 60956 1007573 B ATOM 6689 OH TYR B 385 -22050 10906 55179 1007484 B ATOM 6605 CA GLY B 376 -22151 -6773 61518 1007573 B ATOM 6690 C TYR B 385 -18859 5878 54721 1005957 B ATOM 6606 C GLY B 376 -20645 -7005 61568 1007573 B ATOM 6691 O TYR B 385 -19464 4822 54912 1005957 B ATOM 6607 O GLY B 376 -20155 -7688 62471 1007573 B ATOM 6692 N TYR B 386 -18711 6790 55677 1005704 B ATOM 6608 N GLU B 377 -19903 -6466 60604 10010312 B ATOM 6693 CA TYR B 386 -19294 6586 57001 1005704 B ATOM 6609 CA GLU B 377 -18454 -6639 60592 10010312 B ATOM 6694 CB TYR B 386 -18291 5988 57994 1004870 B ATOM 6610 CB GLU B 377 -17962 -6928 59176 10013199 B ATOM 6695 CG TYR B 386 -17765 4610 57710 1004870 B ATOM 6611 CG GLU B 377 -16511 -7369 59114 10013199 B ATOM 6696 CDl TYR B 386 -16555 4433 57053 1004870 B ATOM 6612 CD GLU B 377 -16055 -7689 57702 10013199 B ATOM 6697 CEl TYR B 386 -16033 3161 56824 1004870 B ATOM 6613 OEl GLU B 377 -14933 -8220 57544 10013199 B ATOM 6698 CD2 TYR B 386 -18454 3473 58136 1004870 B ATOM 6614 OE2 GLU B 377 -16817 -7406 56751 10013199 B ATOM 6699 CE2 TYR B 386 -17945 2189 57915 1004870 B ATOM 6615 C GLU B 377 -17793 -5373 61 119 10010312 B ATOM 6700 CZ TYR B 386 -16732 2043 57257 1004870 B ATOM 6616 O GLU B 377 -17946 -4295 60538 I 00103 12 B ATOM 6701 OH TYR B 386 -16215 0787 57021 1004870 B ATOM 6617 N TYR B 378 -17062 -5505 62224 1008273 B ATOM 6702 C TYR B 386 -19765 7892 57634 1005704 B ATOM 6618 CA TYR B 378 -16398 -4355 62831 1008273 B ATOM 6703 O TYR B 386 18976 8834 57761 1005704 B ATOM 6619 CB TYR B 378 -16424 -4470 64355 1008628 B ATOM 6704 N PRO B 387 -21054 7979 58029 1006554 B ATOM 6620 CG TYR B 378 -17816 -4300 64912 1008628 B ATOM 6705 CD PRO B 387 -22176 7078 57716 100123 15 B ATOM 6621 CDl TYR B 378 -18629 -5405 65167 1008628 B ATOM 6706 CA PRO B 387 -21 534 9214 58667 1006554 B ATOM 6622 CEl TYR B 378 -19952 -5242 65587 1008628 B ATOM 6707 CB PRO B 387 -23014 8933 58872 10012315 B ATOM 6623 CD2 TYR B 378 -18355 -3027 65098 1008628 B ATOM 6708 CG PRO B 387 -23345 8025 57718 10012315 B ATOM 6624 CE2 TYR B 378 19675 -2853 65516 1008628 B ATOM 6709 C PRO B 387 -20742 9193 59980 1006554 B ATOM 6625 CZ TYR B 378 -20467 -3962 65755 1008628 B ATOM 6710 O PRO B 387 -20498 8106 60507 1006554 B ATOM 6626 OH TYR B 378 -21774 -3780 66137 1008628 B ATOM 6711 N GLU B 388 -20336 10332 60540 10011541 B ATOM 6627 C TYR B 378 -14983 -4074 62351 1008273 B ATOM 6712 CA GLU B 388 -19512 10193 61735 10011541 B ATOM 6628 O TYR B 378 .14016 -4191 63102 1008273 B ATOM 6713 CB GLU B 388 -18043 10269 61326 10010313 B ATOM 6629 N LYS B 379 -14894 -3704 61076 1006412 B ATOM 6714 CG GLU B 388 -17600 11635 60860 10010313 B ATOM 6630 CA LYS B 379 -13649 -3335 60421 1006412 B ATOM 6715 CD GLU B 388 -16099 11724 60738 10010313 B ATOM 6631 CB LYS B 379 -13205 -4417 59443 1007993 B ATOM 6716 OEl GLU B 388 15411 11478 61753 10010313 B ATOM 6632 CG LYS B 379 -12772 -5708 60090 1007993 B ATOM 6717 OE2 GLU B 388 -15605 12035 59635 10010313 B ATOM 6633 CD LYS B 379 -12363 -6715 59024 1007993 B ATOM 6718 C GLU B 388 -19655 10975 63032 10011541 B ATOM 6634 CE LYS B 379 -12115 -8105 59606 1007993 B ATOM 6719 O GLU B 388 18695 11017 63796 10011541 B ATOM 6635 NZ LYS B 379 -11891 -9128 58530 1007993 B ATOM 6720 N TRP B 389 -20799 11580 63326 1009126 ATOM 6636 C LYS B 379 -13948 -2044 59659 1006412 B ATOM 6721 CA TRP B 389 -20903 12290 64607 1009126 B ATOM 6637 O LYS B 379 -15009 -1910 59044 1006412 B ATOM 6722 CB TRP B 389 -20870 11285 65770 100113 13 B ATOM 6638 N TYR B 380 -13029 -1088 59723 I 005689 B ATOM 6723 CG TRP B 389 -22195 10873 66332 10011313 B ATOM 6639 CA TYR B 380 -13215 0172 59014 1005689 B ATOM 6724 CD2 TRP B 389 -23482 11427 66023 10011313 B ATOM 6640 CB TYR B 380 -12456 1282 59729 1005569 B ATOM 6725 CE2 TRP B 389 -24428 10745 66817 10011313 B ATOM 6641 CG TYR B 380 -12668 2651 59145 1005569 B ATOM 6726 CE3 TRP B 389 -23929 12435 65154 10011313 B ATOM 6642 CDl TYR B 380 -13741 3437 59547 1005569 B ATOM 6727 CDl TRP B 389 -22411 9907 67271 100113 13 B ATOM 6643 CEl TYR B 380 13926 4707 59037 1005569 B ATOM 6728 NEl TRP B 389 -23746 9823 67568 10011313 B ATOM 6644 CD2 TYR B 380 -11780 3169 58202 1005569 B ATOM 6729 CZ2 TRP B 389 -25798 11037 66768 10011313 B ATOM 6645 CE2 TYR B 380 -11955 4438 57673 1005569 B ATOM 6730 CZ3 TRP B 389 -25291 12726 65106 10011313 B ATOM 6646 CZ TYR B 380 -13029 5209 58097 1005569 B ATOM 6731 CH2 TRP B 389 -26208 12028 65910 10011313 B ATOM 6647 OH TYR B 380 -13192 6491 57605 1005569 B ATOM 6732 C TRP B 389 -19755 13282 64816 1009126 ATOM 6648 C TYR B 380 -12647 -0018 57607 1005689 B ATOM 6733 O TRP B 389 -18872 13044 65645 1009126 ATOM 6649 O TYR B 380 -11441 -0189 57446 1005689 B ATOM 6734 N GLY B 390 -19767 14391 64083 1008015 B ATOM 6650 N VAL B 381 -13510 -0003 56596 1005530 B ATOM 6735 CA GLY B 390 -18703 15369 64226 1008015 B ATOM 6651 CA VAL B 381 -13067 -0196 55215 1005530 B ATOM 6736 C GLY B 390 -18615 16025 65594 1008015 B ATOM 6652 CB VAL B 381 -14216 -0745 54342 1004351 B ATOM 6737 O GLY B 390 -19608 16114 66317 1008015 B ATOM 6653 CGl VAL B 381 -13711 -1034 52953 1004351 B ATOM 6738 N ARG B 391 -17413 16472 65955 10010400 B ATOM 6654 CG2 VAL B 381 -14771 -2008 54959 1004351 B ATOM 6739 CA ARG B 391 -17184 17153 67228 10010400 B ATOM 6655 C VAL B 381 -12550 1 113 54622 1005530 B ATOM 6740 CB ARG B 391 -15759 16887 67721 1008699 B ATOM 6656 O VAL B 381 -13289 2094 54533 1005530 B ATOM 6741 CG ARG B 391 -15436 15407 67917 1008699 B ATOM 6657 N ASN B 382 -11291 1 110 54195 1006253 B ATOM 6742 CD ARG B 391 -15615 14943 69369 1008699 B ATOM 6658 CA ASN B 382 -10658 2302 53668 1006253 B ATOM 6743 NE ARG B 391 -14386 15065 70169 1008699 ATOM 6659 CB ASN B 382 9443 i 943 52836 1004047 B ATOM 6744 CZ ARG B 391 -13911 16203 70679 1008699 ATOM 6660 CG ASN B 382 -8429 3091 52757 1004047 B ATOM 6745 NHl ARG B 391 -14560 17350 70486 1008699 ATOM 6661 ODl ASN B 382 -8789 4283 52791 1004047 B ATOM 6746 NH2 ARG B 391 -12780 16195 71379 1008699 65251/C766

ATOM 6747 C ARG B 391 -17382 18645 66954 10010400 B ATOM 6832 CZ PHE B 402 -12100 17861 67008 1005737 B ATOM 674S O ARG B 391 -17457 19059 65799 10010400 B ATOM 6833 C PHE B 402 -7691 20039 69067 1006603 B ATOM 6749 N LYS B 392 -17481 19456 68000 1006999 B ATOM 6834 O PHE B 402 -6634 19469 69343 1006603 B ATOM 6750 CA LYS B 392 -17676 20889 67805 1006999 B ATOM 6835 N PRO B 403 -8682 20197 69971 1006557 B ATOM 6751 CB LYS B 392 -18893 21379 68599 10010630 B ATOM 6836 CD PRO B 403 -9953 20872 69689 1003909 B ATOM 6752 CG LYS B 392 -19159 22876 68457 10010630 B ATOM 6837 CA PRO B 403 -8650 19754 71374 1006557 B ATOM 6753 CD LYS B 392 20211 23359 69445 10010630 B ATOM 6838 CB PRO B 403 -9902 20386 71980 10014392 B ATOM 6754 CE LYS B 392 -20329 24874 69415 10010630 B ATOM 6839 CG PRO B 403 -10275 21451 71034 1003909 B ATOM 6755 NZ LYS B 392 -21213 25391 70498 10010630 B ATOM 6840 C PRO B 403 -8677 18250 71552 1006557 B ATOM 6756 C LYS B 392 -16439 21 679 68229 1006999 B ATOM 6841 O PRO B 403 -9727 17635 71433 1006557 B ATOM 6757 O LYS B 392 -16072 21 694 69408 1 006999 B ATOM 6842 N TRP B 404 -7525 17652 71815 1007255 B ATOM 6758 N SER B 393 -15798 22336 67265 1005264 B ATOM 6843 CA TRP B 404 -7462 16214 72052 1007255 B ATOM 6759 CA SER B 393 -14598 23128 67530 1005264 B ATOM 6844 CB TRP B 404 -6518 15509 71068 1007570 B ATOM 6760 CB SER B 393 -13384 22208 67726 1007094 B ATOM 6845 CG TRP B 404 -7053 15330 69671 1006894 B ATOM 6761 OG SER B 393 -12184 22944 67901 1007094 B ATOM 6846 CD2 TRP B 404 -8210 14575 69273 1006894 B ATOM 6762 C SER B 393 -14337 24067 66370 1005264 B ATOM 6847 CE2 TRP B 404 -8293 14653 67866 1006894 B ATOM 6763 O SER B 393 -14818 23833 65264 1005264 B ATOM 6848 CE3 TRP B 404 9183 13840 69968 1006894 B ATOM 6764 N ASN B 394 -13590 25139 66616 1005304 B ATOM 6849 CDl TRP B 404 -6505 15818 68522 1006894 B ATOM 6765 CA ASN B 394 -13272 26068 65541 1005304 B ATOM 6850 NEl TRP B 404 -7242 15417 67436 1006894 B ATOM 6766 CB ASN B 394 -12779 27388 66100 1005987 B ATOM 6851 CZ2 TRP B 404 -9309 14026 67137 1006894 B ATOM 6767 CG ASN B 394 -13882 28184 66735 1005987 B ATOM 6852 CZ3 TRP B 404 -10196 13213 69242 1006894 B ATOM 6768 ODl ASN B 394 -14950 28366 66143 1005987 B ATOM 6853 CH2 TRP B 404 -10248 13312 67840 1006894 B ATOM 6769 ND2 ASN B 394 -13634 28675 67949 1005987 B ATOM 6854 C TRP B 404 -6910 16081 73458 1007255 B ATOM 6770 C ASN B 394 -12203 25456 64653 1 005304 B ATOM 6855 O TRP B 404 5904 16702 73787 1007255 B ATOM 6771 O ASN B 394 -12010 25873 63511 1005304 B ATOM 6856 N ASN B 405 -7564 15286 74293 1006360 B ATOM 6772 N TYR B 395 11515 24463 65196 1006010 B ATOM 6857 CA ASN B 405 -7097 15114 75657 1006363 B ATOM 6773 CA TYR B 395 -10477 23767 64475 1006010 B ATOM 6858 CB ASN B 405 -8227 14598 76535 1 007615 B ATOM 6774 CB TYR B 395 -9331 23424 65423 1004811 B ATOM 6859 CG ASN B 405 -7996 14891 77986 1007615 B ATOM 6775 CG TYR B 395 -8622 24617 65997 1004811 B ATOM 6860 ODl ASN B 405 -7133 14293 78622 1007615 B ATOM 6776 CDl TYR B 395 -8970 25126 67238 1004811 B ATOM 6861 ND2 ASN B 405 -8758 15836 78523 1007615 B ATOM 6777 CEl TYR B 395 -8312 26234 67774 1004811 B ATOM 6862 C ASN B 405 -5917 14149 75693 1007257 B ATOM 6778 CD2 TYR B 395 -7595 25244 65295 1004811 B ATOM 6863 O ASN B 405 -6050 12983 76092 1006563 B ATOM 6779 CE2 TYR B 395 -6934 26349 65817 1004811 B ATOM 6864 N ILE B 406 -4763 14647 75259 1006969 B ATOM 6780 CZ TYR B 395 -7299 26839 67059 1004811 B ATOM 6865 CA ILE B 406 -3550 13850 75232 10061 89 B ATOM 6781 OH TYR B 395 -6659 27945 67579 1004811 B ATOM 6866 CB ILE B 406 -2875 13909 73851 1006456 B ATOM 6782 C TYR B 395 -11043 22475 63882 1006010 B ATOM 6867 CG2 ILE B 406 -1672 12977 73812 1005218 B ATOM 6783 O TYR B 395 -12028 21937 64379 1006010 B ATOM 6868 CGl ILE B 406 -3880 13517 72770 1005218 B ATOM 6784 N GLU B 396 -10422 21983 62816 1005953 B ATOM 6869 CDl ILE B 406 -3296 13494 71364 1005218 B ATOM 6785 CA GLU B 396 -10831 20731 62187 1005953 B ATOM 6870 C ILE B 406 2572 14384 76259 1006876 B ATOM 6786 CB GLU B 396 -10779 20856 60670 10011469 B ATOM 6871 O ILE B 406 -2467 15588 76457 1006386 B ATOM 6787 CG GLU B 396 -11438 22095 60121 10011469 B ATOM 6872 N LYS B 407 -1868 13480 76921 1004685 B ATOM 6788 CD GLU B 396 -11 130 22295 58650 10011469 B ATOM 6873 CA LYS B 407 -0867 13851 77913 1004245 B ATOM 6789 OEl GLU B 396 -9931 22311 58292 10011469 B ATOM 6874 CB LYS B 407 -1407 13700 79336 10010776 B ATOM 6790 OE2 GLU B 396 -12080 22439 57854 10011469 B ATOM 6875 CG LYS B 407 -2577 14601 79675 1009386 B ATOM 6791 C GLU B 396 -9811 19675 62628 1005953 B ATOM 6876 CD LYS B 407 -2895 14524 81 162 1009386 B ATOM 6792 O GLU B 396 -8609 19958 62709 1005953 B ATOM 6877 CE LYS B 407 -4161 15295 81518 1009386 B ATOM 6793 N PRO B 397 -10265 18448 62930 1005219 B ATOM 6878 NZ LYS B 407 -5373 14685 80906 1009386 B ATOM 6794 CD PRO B 397 11608 17867 62818 1004976 B ATOM 6879 C LYS B 407 0270 12877 77718 1005176 B ATOM 6795 CA PRO B 397 -9292 17432 63347 1005219 B ATOM 6880 O LYS B 407 0033 11698 77447 1005070 B ATOM 6796 CB PRO B 397 -10131 16154 63424 1004976 B ATOM 6881 N LYS B 408 1503 13358 77824 1005597 B ATOM 6797 CG PRO B 397 11287 16433 62518 1004976 B ATOM 6882 CA LYS B 408 2638 12463 77670 1005556 B ATOM 6798 C PRO B 397 -8149 17352 62340 1005219 B ATOM 6883 CB LYS B 408 3927 13250 77485 1006030 B ATOM 6799 O PRO B 397 -8369 17334 61 128 005219 B ATOM 6884 CG LYS B 408 5115 12372 77158 1005910 B ATOM 6800 N GLY B 398 -6926 17320 62851 003952 B ATOM 6885 CD LYS B 408 6295 13206 76729 1005910 B ATOM 6801 CA GLY B 398 -5772 17287 61975 1003952 B ATOM 6886 CE LYS B 408 7456 12336 76328 1005910 B ATOM 6802 C GLY B 398 -4944 18532 62247 1003952 B ATOM 6887 NZ LYS B 408 8574 13154 75770 1005910 B ATOM 6803 O GLY B 398 -3718 18465 62277 1003952 B ATOM 6888 C LYS B 408 2677 11686 78967 1005569 B ATOM 6804 N GLU B 399 -5617 19667 62447 1004499 B ATOM 6889 O LYS B 408 2992 12239 80011 1005426 B ATOM 6805 CA GLU B 399 -494420931 62738 1004499 B ATOM 6890 N ASP B 409 2337 10408 78927 1007313 B ATOM 6806 CB GLU B 399 -5921 22106 62632 1 006178 B ATOM 6891 CA ASP B 409 2331 9660 80169 1007331 B ATOM 6807 CG GLU B 399 -6636 22184 61293 1006178 B ATOM 6892 CB ASP B 409 1688 8271 79977 1009509 B ATOM 6808 CD GLU B 399 -7567 23382 61 162 1006178 B ATOM 6893 CG ASP B 409 2204 7534 78762 1008791 B ATOM 6809 OEl GLU B 399 -8292 23690 62128 1006178 B ATOM 6894 ODl ASP B 409 3435 7484 78569 1008791 B ATOM 6810 OE2 GLU B 399 -7588 24008 60081 1006178 B ATOM 6895 OD2 ASP B 409 1371 6986 78011 1008791 B ATOM 6811 C GLU B 399 -4445 20819 64162 1004499 B ATOM 6896 C ASP B 409 3700 9551 80844 1007322 B ATOM 6812 O GLU B 399 -5163 20327 65022 1004499 B ATOM 6897 O ASP B 409 4733 9804 80222 1007695 B ATOM 6813 N PRO B 400 -3206 21258 64441 1005904 B ATOM 6898 N LYS B 410 3661 9205 82134 1009450 B ATOM 6814 CD PRO B 400 -2156 21823 63584 1003485 B ATOM 6899 CA LYS B 410 4825 9037 83008 10010094 B ATOM 6815 CA PRO B 400 -2741 21 135 65824 1005412 B ATOM 6900 CB LYS B 410 4566 7901 84008 10017356 B ATOM 6816 CB PRO B 400 -1328 21723 65778 1008346 B ATOM 6901 CG LYS B 410 4493 6492 83393 10011301 B ATOM 6817 CG PRO B 400 -1338 22583 64576 1003485 B ATOM 6902 CD LYS B 410 3214 6259 82585 10011301 B ATOM 6818 C PRO B 400 -3644 21804 66847 1004487 B ATOM 6903 CE LYS B 410 3 199 4873 81946 10011301 B ATOM 6819 O PRO B 400 -3603 21470 68029 1004508 B ATOM 6904 NZ LYS B 410 1969 4633 81 140 10011301 B ATOM 6820 N GLY B 401 -4485 22723 66393 1005579 B ATOM 6905 C LYS B 410 6133 8762 82287 1009976 B ATOM 6821 CA GLY B 401 -5385 23398 67313 1005535 B ATOM 6906 O LYS B 410 6139 8230 81 183 1009929 B ATOM 6822 C GLY B 401 -6571 22581 67812 1005514 B ATOM 6907 N ASP B 411 7238 9109 82941 1007544 B ATOM 6823 O GLY B 401 -7279 23011 68717 1005585 ATOM 6908 CA ASP B 411 8586 8927 82393 1007295 B ATOM 6824 N PHE B 402 -6804 21408 67235 1006603 ATOM 6909 CB ASP B 411 9569 8538 83502 10017979 B ATOM 6825 CA PHE B 402 -7928 20583 67662 1006603 ATOM 6910 CG ASP B 411 10186 9746 84186 10017979 B ATOM 6826 CB PHE B 402 -8132 19423 66706 10015904 ATOM 6911 ODl ASP B 411 10714 10628 83475 10017979 B ATOM 6827 CG PHE B 402 -9500 18853 66773 1005737 ATOM 6912 OD2 ASP B411 10152 9812 85431 10017979 B ATOM 6828 CDl PHE B 402 -10568 19532 66207 1005737 ATOM 6913 C ASP B 411 8704 7925 81253 1007456 B ATOM 6829 CD2 PHE B 402 -9744 17669 67454 1005737 ATOM 6914 O ASP B 411 9055 6762 81465 1007874 B ATOM 6830 CEl PHE B 402 -11867 19041 66321 1005737 ATOM 6915 N ALA B 412 8421 8400 80041 1009893 B ATOM 6831 CE2 PHE B 402 -11035 17171 67576 1005737 ATOM 6916 CA ALA B 412 8473 7580 78837 1001 II 95 B 65251/C766

ATOM 6917 CB ALA B 412 7 375 6 520 78 873 1 00 7771 B ATOM 7002 N THR B 423 23648 10513 74733 1007606 B ATOM 6918 C ALA B 412 8 302 8460 77 605 1 00106 65 B ATOM 7003 CA THR B 423 -24577 9594 74079 1008571 B ATOM 6919 O ALA B 412 8 002 9 648 77 715 1 00101 70 B ATOM 7004 CB THR B 423 24548 8196 74743 I 0013151 B ATOM 6920 N ASN B 413 8 485 7 866 76 432 1 00 63 52 B ATOM 7005 OGl THR B 423 -23210 7693 74730 1008730 B ATOM 6921 CA ASN B 413 8 356 8 598 75 179 1 005633 B ATOM 7006 CG2 THR B 423 -25440 7215 73989 1008730 B ATOM 6922 CB ASN B 413 9 305 8 032 74 138 1 00 6296 B ATOM 7007 C THR B 423 -26018 10099 74100 1008393 B ATOM 6923 CG ASN B 413 10 746 8 149 74 554 1 00 62 96 B ATOM 7008 O THR B 423 -26881 9474 74699 1008242 B ATOM 6924 ODl ASN B 413 11 163 9 179 75 084 1 0062 96 B ATOM 7009 N THR B 424 -26283 11225 73446 10013280 B ATOM 6925 ND2 ASN B 413 11 525 7 099 74302 1 0062 96 B ATOM 7010 CA THR B 424 -27639 11763 73408 10013280 B ATOM 6926 C ASN B 413 6 955 8 521 74 630 1 00 60 91 B ATOM 7011 CB THR B 424 -27689 13115 72674 10019802 B ATOM 6927 O ASN B 413 6 594 9259 73 724 1 00 60 60 B ATOM 7012 OGl THR B 424 -26801 14036 73318 10014383 B ATOM 6928 N THR B 414 6 169 7 627 75 204 1 0040 68 B ATOM 7013 CG2 THR B 424 -29102 13688 72699 10014383 B ATOM 6929 CA THR B 414 4 805 7 396 74 772 1 0043 72 B ATOM 7014 C THR B 424 -28539 10767 72688 10013280 B ATOM 6930 CB THR B 414 4413 5 967 75 147 1 0010847 B ATOM 7015 O THR B 424 -28064 9955 71893 10013280 B ATOM 6931 OGl THR B 414 3 081 5 725 74 720 1 00 78 96 B ATOM 7016 N SER B 425 -29836 10831 72969 10013308 B ATOM 6932 CG2 THR B 4I4 4 516 5 750 76 640 1 00 78 96 B ATOM 7017 CA SER B 425 -30797 9918 72361 10013308 B ATOM 6933 C THR B 414 3 762 8410 75 281 1 0043 18 B ATOM 7018 CB SER B 425 -32103 9954 73146 10017300 B ATOM 6934 O THR B 414 4 042 9 192 76 199 1 00 4425 B ATOM 7019 OG SER B 425 -33015 9017 72621 1006894 B ATOM 6935 N TYR B 415 2 581 8417 74 656 1 0048 38 B ATOM 7020 C SER B 425 31083 10195 70885 10013308 B ATOM 6936 CA TYR B 415 1 491 9 328 75 027 1 004941 B ATOM 7021 O SER B 425 -31 854 9475 70250 10013308 B ATOM 6937 CB TYR B 415 1 243 10 359 73 930 1 00 7723 B ATOM 7022 N LYS B 426 -30458 11233 70342 10015781 B ATOM 6938 CG TYR B 415 2 373 11 322 73 717 1 0044 17 B ATOM 7023 CA LYS B 426 -30648 11593 68941 10015781 B ATOM 6939 CDl TYR B 415 3 572 10 897 73 160 1 0044 17 B ATOM 7024 CB LYS B 426 -29774 12795 68583 10020084 B ATOM 6940 CEl TYR B 415 4 623 11 791 72 962 1 00 44 17 B ATOM 7025 CG LYS B 426 -29916 13977 69517 10015366 B ATOM 6941 CD2 TYR B 415 2 245 12 673 74078 1 0044 17 B ATOM 7026 CD LYS B 426 -28880 15036 69195 10015366 B ATOM 6942 CE2 TYR B 415 3 287 13 575 73 887 1 00 44 17 B ATOM 7027 CE LYS B 426 -28911 16160 70210 10015366 B ATOM 6943 CZ TYR B 415 4473 13 125 73 328 1 00 44 17 B ATOM 7028 NZ LYS B 426 -27865 17176 69915 10015366 B ATOM 6944 OH TYR B 415 5 520 13 992 73 128 1 00 44 17 B ATOM 7029 C LYS B 426 -30284 10430 68024 10015781 B ATOM 6945 C TYR B 415 0 179 8 589 75 260 1 00 5697 B ATOM 7030 O LYS B 426 -30951 10187 67029 10015781 B ATOM 6946 O TYR B 415 0 009 7451 74 812 1 00 51 62 B ATOM 7031 N MET B 427 -29218 9716 68371 10011958 B ATOM 6947 N SER B 416 0 756 9 248 75 943 1 00 71 09 B ATOM 7032 CA MET B 427 -28740 8590 67575 10011958 B ATOM 6948 CA SER B 416 -2 060 8 654 76215 1 00 69 04 B ATOM 7033 CB MET B 427 -27386 8114 68106 10012141 B ATOM 6949 CB SER B 416 -2 153 8203 77 668 1 00 94 22 B ATOM 7034 CG MET B 427 -27369 7836 69599 10012141 B ATOM 6950 OG SER B 416 -1 393 7 024 77 870 1 00 7060 B ATOM 7035 SD MET B 427 -25743 7338 70179 10012141 B ATOM 6951 C SER B 416 -3 172 9 633 75 906 1 0075 23 B ATOM 7036 CE MET B 427 -24896 8924 70232 10012141 B ATOM 6952 O SER B 416 -2991 10 845 76 011 1 00 73 60 B ATOM 7037 C MET B 427 -29710 7420 67537 10011958 B ATOM 6953 N LEU B 417 -4 327 9095 75 530 1 00 56 22 B ATOM 7038 O MET B 427 -30894 7576 67834 10011958 B ATOM 6954 CA LEU B 417 -5 477 9 914 75 164 1 0055 12 B ATOM 7039 N SER B 428 -29197 6247 67168 10010822 B ATOM 6955 CB LEU B 417 -5 605 9 936 73 644 1 00 89 62 B ATOM 7040 CA SER B 428 -30019 5049 67083 10010987 B ATOM 6956 CG LEU B 417 -7015 10 181 73 112 1 00 47 73 B ATOM 7041 CB SER B 428 -31022 5185 65932 10010701 B ATOM 6957 CDl LEU B 417 -7 353 11 660 73 198 1 0047 73 B ATOM 7042 OG SER B 428 30361 5289 64680 10010372 B ATOM 6958 CD2 LEU B 417 -7 102 9 702 71 682 1 00 4773 B ATOM 7043 C SER B 428 -29200 3778 66883 10010582 B ATOM 6959 C LEU B 417 -6 796 9 431 75 767 1 00 6663 B ATOM 7044 O SER B 428 -29677 2834 66262 10010570 B ATOM 6960 O LEU B 417 -6 982 8 237 76 019 1 00 61 73 B ATOM 7045 N SER B 429 -27976 3748 67404 10013630 B ATOM 6961 N THR B 418 -7 710 10374 75 977 1 00 62 97 B ATOM 7046 CA SER B 429 27126 2566 67261 10013497 B ATOM 6962 CA THR B 418 -9 027 10074 76 521 1 00 56 03 B ATOM 7047 CB SER B 429 -26509 2512 65860 10012474 B ATOM 6963 CB THR B 418 -9 115 10 420 78 016 1 00107 83 B ATOM 7048 OG SER B 429 -27497 2378 64857 10012474 B ATOM 6964 OGl THR B 418 -8 344 9475 78 769 1 00 76 24 B ATOM 7049 C SER B 429 -25997 2516 68282 10013335 B ATOM 6965 CG2 THR B 418 10562 10 389 78486 1 00 7624 B ATOM 7050 O SER B 429 -25301 1 507 68393 10012205 B ATOM 6966 C THR B 418 10 063 10 897 75 782 1 00 71 22 B ATOM 7051 N GLN B 430 -25819 3600 69028 10011066 B ATOM 6967 O THR B 418 -10072 12 118 75 889 1 0064 69 B ATOM 7052 CA GLN B 430 -24745 3681 70012 10011066 B ATOM 6968 N ASP B 419 -10 936 10 238 75 029 1 00 63 11 B ATOM 7053 CB GLN B 430 -24795 2520 70998 10019445 B ATOM 6969 CA ASP B 419 11 959 10966 74 289 I 00 68 22 B ATOM 7054 CG GLN B 430 -23718 2631 72053 10012344 B ATOM 6970 CB ASP B 419 -11 832 10677 72 794 1 00 96 97 B ATOM 7055 CD GLN B 430 -23712 1469 73008 10012344 B ATOM 6971 CG ASP B 419 -12 61 1 11 658 71 955 1 00 74 56 B ATOM 7056 OEl GLN B 430 -23371 0342 72636 10012344 B ATOM 6972 ODl ASP B 419 -12 465 12 875 72 188 1 0074 56 B ATOM 7057 NE2 GLN B 430 -24097 1731 74253 10012344 B ATOM 6973 OD2 ASP B 419 -13 368 11 221 71 064 1 0074 56 B ATOM 7058 C GLN B 430 -23424 3639 69256 10011066 B ATOM 6974 C ASP B 419 -13 353 10601 74791 1 0072 31 B ATOM 7059 O GLN B 430 -23051 2607 68687 10011066 B ATOM 6975 O ASP B 419 -13 726 9429 74 814 1 00 67 20 B ATOM 7060 N PRO B 431 -22682 4757 69266 1007877 B ATOM 6976 N LEU B 420 -14 118 11 613 75 189 1 00 89 62 B ATOM 7061 CD PRO B 431 -22818 5929 70148 1006222 B ATOM 6977 CA LEU B 420 -15 460 11 407 75 723 1 00 94 31 B ATOM 7062 CA PRO B 431 -21411 4808 68556 1007876 B ATOM 6978 CB LEU B 420 -15 620 12 242 76 996 1 00149 06 B ATOM 7063 CB PRO B 431 -20946 6234 68800 100161 18 B ATOM 6979 CG LEU B 420 -16 715 11 837 77 979 1 00108 01 B ATOM 7064 CG PRO B 431 21411 6477 70178 10013174 B ATOM 6980 CDl LEU B 420 -16 391 10 464 78 552 1 0010801 B ATOM 7065 C PRO B 431 -20398 3790 69013 1007538 B ATOM 6981 CD2 LEU B 420 -16 818 12 870 79 093 1 00108 01 B ATOM 7066 O PRO B 431 -20468 3265 70121 1007526 B ATOM 6982 C LEU B 420 -16 545 11 787 74 715 1 0096 88 B ATOM 7067 N VAL B 432 -19468 3511 68112 1006848 B ATOM 6983 O LEU B 420 -16 315 12 613 73 837 1 009620 B ATOM 7068 CA VAL B 432 -18375 2597 68355 1007086 B ATOM 6984 N VAL B 421 -17 726 11 183 74 840 1 00 84 12 B ATOM 7069 CB VAL B 432 -18395 1455 67345 1009160 B ATOM 6985 CA VAL B 421 -18 843 11 480 73 940 1 00 82 63 B ATOM 7070 CGl VAL B 432 -18260 2000 65949 1006368 B ATOM 6986 CB VAL B 421 -18 890 10485 72 776 1 00110 16 B ATOM 7071 CG2 VAL B 432 -17295 0498 67643 1006368 B ATOM 6987 CGl VAL B 421 -20 124 10 715 71 929 1 00 65 59 B ATOM 7072 C VAL B 432 -17164 3504 68134 1006886 B ATOM 6988 CG2 VAL B 421 17671 10 659 71 932 1 0065 59 B ATOM 7073 O VAL B 432 -17237 4458 67362 1005922 B ATOM 6989 C VAL B 421 -20 193 11 458 74 644 1 00 84 89 B ATOM 7074 N CYS B 433 -16064 3240 68821 1006616 B ATOM 6990 O VAL B 421 -20 481 10 549 75 422 1 00 8049 B ATOM 7075 CA CYS B 433 -14894 4094 68676 1006204 B ATOM 6991 N ARG B 422 -21 019 12 459 74 356 1 00105 63 B ATOM 7076 C CYS B 433 -13911 3573 67634 1005968 B ATOM 6992 CA ARG B 422 -22 349 12 577 74949 1 00107 76 B ATOM 7077 O CYS B 433 -13441 2435 67729 1006042 B ATOM 6993 CB ARG B 422 -22 808 14 038 74 874 1 0018906 B ATOM 7078 CB CYS B 433 -14189 4237 70029 10015195 B ATOM 6994 CG ARG B 422 -23 213 14 663 76 198 1 00149 65 B ATOM 7079 SG CYS B 433 12789 5401 70030 1009906 B ATOM 6995 CD ARG B 422 -24 602 14228 76632 1 00149 65 B ATOM 7080 N VAL B 434 -13610 4401 66629 1006471 B ATOM 6996 NE ARG B 422 -25 032 14949 77 826 1 00149 65 B ATOM 7081 CA VAL B 434 -12644 4030 65590 1006070 B ATOM 6997 CZ ARG B 422 -26255 14885 78343 1 00149 65 B ATOM 7082 CB VAL B 434 -13149 4349 64188 1006515 B ATOM 6998 NHl ARG B 422 -27 181 14 126 77 770 1 00149 65 B ATOM 7083 CGl VAL B 434 -12205 3752 63 163 1004693 B ATOM 6999 NH2 ARG B 422 -26 552 15 587 79 430 1 00149 65 B ATOM 7084 CG2 VAL B 434 -14529 3795 64000 1004693 B ATOM 7000 C ARG B 422 -23 336 11 686 74 189 1 0010499 B ATOM 7085 C VAL B 434 -11378 4840 65831 10071 10 B ATOM 7001 O ARG B 422 23 808 12 061 73 119 1 0095 66 B ATOM 7086 O VAL B 434 -11404 6071 65768 1006216 B 65251/C766

ATOM 7087 N VAL B 435 -10278 4142 66101 1005072 B ATOM 7172 CDl TYR B 445 -10489 0609 69020 1005516 B ATOM 7088 CA VAL B 435 -9005 4786 66399 1004246 B ATOM 7173 CEl TYR B 445 -9169 0360 68602 10055 16 B ATOM 7089 CB VAL B 435 -8341 4103 67616 1005398 B ATOM 7174 CD2 TYR B 445 -10432 -1352 70395 1005516 B ATOM 7090 CGl VAL B 435 -6917 4591 67803 1003331 B ATOM 7175 CE2 TYR B 445 9115 1611 69985 10055 16 B ATOM 7091 CG2 VAL B 435 -9160 4384 68850 1003331 B ATOM 7176 CZ TYR B 445 -8491 -0754 69093 1005516 B ATOM 7092 C VAL B 435 -8017 4790 65238 1005038 B ATOM 7177 OH TYR B 445 -7193 -1014 68717 1005516 B ATOM 7093 O VAL B 435 -7650 3729 64724 1005097 B ATOM 7178 C TYR B 445 14985 -0410 69982 1006156 B ATOM 7094 N PHE B 436 -7581 5981 64830 1004971 B ATOM 7179 O TYR B 445 -15533 0678 69761 1006442 B ATOM 7095 CA PHE B 436 -6613 6108 63746 1004591 B ATOM 7180 N THR B 446 -15557 -1378 70696 1006255 B ATOM 7096 CB PHE B 436 -7041 7190 62764 1006446 B ATOM 7181 CA THR B 446 -16929 -1237 71 171 1006953 B ATOM 7097 CG PHE B 436 -8322 6889 62061 1003923 B ATOM 7182 CB THR B 446 -17781 -2358 70579 1007477 B ATOM 7098 CDl PHE B 436 -9536 7256 62619 1003923 B ATOM 7183 OGl THR B 446 -17183 -3615 70912 1006292 B ATOM 7099 CD2 PHE B 436 8318 6228 60834 1003923 B ATOM 7184 CG2 THR B 446 -17853 -2244 69084 1006292 B ATOM 7100 CEl PHE B 436 -10739 6974 61963 1003923 B ATOM 7185 C THR B 446 -17193 -1222 72679 1007933 B ATOM 7101 CE2 PHE B 436 -9511 5937 60168 1003923 B ATOM 7186 O THR B 446 -16329 -0882 73487 1008300 B ATOM 7102 CZ PHE B 436 -10723 6310 60732 1003923 B ATOM 7187 N CYS B 447 -18436 -1592 72999 1009079 B ATOM 7103 C PHE B 436 -5232 6439 64298 1005374 B ATOM 7188 CA CYS B 447 -19040 -1724 74334 1009177 B ATOM 7104 O PHE B 436 -5039 7480 64921 1005312 B ATOM 7189 C CYS B 447 -19220 -0516 75242 1009180 B ATOM 7105 N HIS B 437 -4281 5537 64074 1003745 B ATOM 7190 O CYS B 447 -18380 0371 75316 1008866 B ATOM 7106 CA HIS B 437 -2918 5727 64543 1003852 B ATOM 7191 CB CYS B 447 -18376 2866 75124 10013624 B ATOM 7107 CB HIS B 437 -2772 5186 65949 10066 S6 B ATOM 7192 SG CYS B 447 -16599 -2717 75446 10012177 B ATOM 7108 CG HIS B 437 -1403 5371 66519 1004323 B ATOM 7193 N SER B 448 -20363 0512 75923 10018930 B ATOM 7109 CD2 HIS B 437 -0354 4520 66607 1004323 B ATOM 7194 CA SER B 448 20743 0542 76853 10018930 B ATOM 7110 NDl HIS B 437 -0974 6566 67065 I 004323 B ATOM 7195 CB SER B 448 -21930 1334 76305 10020084 B ATOM 711 1 CEl HIS B 437 0277 6441 67464 1004323 B ATOM 7196 OG SER B 448 -21611 1920 75056 10020084 B ATOM 7112 NE2 HIS B 437 0677 5211 67196 1004323 B ATOM 7197 C SER B 448 -21 114 -0086 78191 10018930 B ATOM 7113 C HIS B 437 -1958 4992 63614 1004283 B ATOM 7198 O SER B 448 -20654 -1 185 78508 10018930 B ATOM 7114 O HIS B 437 -2374 4078 62900 1004505 B ATOM 7199 N GLU B 449 -21964 0594 78961 10015292 B ATOM 7115 N ASP B 438 -0683 5385 63614 1003451 B ATOM 7200 CA GLU B 449 -22357 0110 80283 10015292 B ATOM 7116 CA ASP B 438 0315 4755 62746 1003642 B ATOM 7201 CB GLU B 449 -22828 -1349 80220 10013425 B ATOM 7117 CB ASP B 438 1700 5364 62998 10010196 B ATOM 7202 CG GLU B 449 -24262 -1530 79753 10013425 B ATOM 7118 CG ASP B 438 1932 6637 62189 1007292 B ATOM 7203 CD GLU B 449 -24577 -0707 78525 10013425 B ATOM 7119 ODl ASP B 438 0928 7278 61 797 1007292 B ATOM 7204 OEl GLU B 449 -23842 -0838 77524 10013425 B ATOM 7120 OD2 ASP B 438 3 114 6995 61953 1007292 B ATOM 7205 OE2 GLU B 449 -25556 0070 78560 10013425 B ATOM 7121 C ASP B 438 0340 3247 62918 1003776 B ATOM 7206 C GLU B 449 -21 114 0207 81 154 10015292 B ATOM 7122 O ASP B 438 0360 2511 61938 1004132 B ATOM 7207 O GLU B 449 -21 165 0644 82301 10015292 B ATOM 7123 N THR B 439 0356 2783 64160 I 007630 B ATOM 7208 N GLY B 450 -19993 -0196 80569 1008126 B ATOM 7124 CA THR B 439 0312 1352 64420 1007365 B ATOM 7209 CA GLY B 450 -18711 -0176 81241 1008126 B ATOM 7125 CB THR B 439 0783 1048 65845 1006250 B ATOM 7210 C GLY B 450 -17949 -1353 80681 1008126 B ATOM 7126 OGl THR B 439 -0081 1694 66784 1004831 B ATOM 721 1 O GLY B 450 -16900 -1740 81 198 1008126 B ATOM 7127 CG2 THR B 439 2186 1587 66058 1004831 B ATOM 7212 N CYS B 451 -18491 -1917 79605 10016743 B ATOM 7128 C THR B 439 -1 189 1 127 64272 1007942 B ATOM 7213 CA CYS B 451 -17901 -3075 78953 10016743 B ATOM 7129 O THR B 439 -1966 2016 64598 10079 ⁷ 6 B ATOM 7214 CB CYS B 451 -16505 -2758 78451 10016196 B ATOM 7130 N LEU B 440 -1 614 -0026 63775 1007965 B ATOM 7215 SG CYS B 451 -16519 -1 558 77101 10016196 B ATOM 7131 CA LEU B 440 -3047 -0272 63549 1008167 B ATOM 7216 C CYS B 451 17824 ^216 79938 10016743 B ATOM 7132 CB LEU B 440 -3834 -0462 64877 1008542 B ATOM 7217 O CYS B 451 -16703 4728 80143 10016743 B ATOM 7133 CG LEU B 440 -4141 0414 66125 1006542 B ATOM 7218 OXT CYS B 451 18886 -4574 80488 10013433 B ATOM 7134 CDl LEU B 440 -2891 0624 66918 1006542 B ATOM 7219 CB ARG C -15415 15094 12139 10013376 C ATOM 7135 CD2 LEU B 440 -4793 1733 65775 1006542 B ATOM 7220 CG ARG C -13880 15204 12120 10013376 C ATOM 7136 C LEU B 440 -3708 0831 62706 1009162 B ATOM 7221 CD ARG C -13343 16332 11234 10013376 C ATOM 7137 O LEU B 440 -4429 1664 63239 1008984 B ATOM 7222 NE ARG C -13137 17588 11962 10013376 C ATOM 7138 N GLU B 441 -3469 0820 61391 1006237 B ATOM 7223 CZ ARG C -12253 17761 12944 10013376 C ATOM 7139 CA GLU B 441 -4023 1 823 60474 1006237 B ATOM 7224 NHl ARG C 1 -11476 16759 13333 10013376 C ATOM 7140 CB GLU B 441 -4139 1242 59064 10020084 B ATOM 7225 NH2 ARG C 1 -12147 18942 13542 10013376 C ATOM 7141 CG GLU B 441 -2799 090S 58434 10014084 B ATOM 7226 C ARG C 1 -15665 16702 14064 10020084 C ATOM 7142 CD OLU B 441 -2923 0493 56979 10014084 B ATOM 7227 O ARG C 1 -14566 17237 14205 10020084 C ATOM 7143 OEl GLU B 441 -3651 -0483 56702 10014084 B ATOM 7228 N ARG C 1 -16048 17452 11715 10020084 C ATOM 7144 OE2 GLU B 441 -2292 1 140 56113 10014084 B ATOM 7229 CA ARG C 1 -16178 16317 12672 10020084 C ATOM 7145 C GLU B 441 -5373 2407 60901 1006237 B ATOM 7230 N THR C 2 -16468 16432 15090 10020007 C ATOM 7146 O GLU B 441 -5584 3624 60844 1006237 B ATOM 7231 CA THR C 2 -16096 16756 16467 10020007 C ATOM 7147 N ALA B 442 -6288 1544 61329 I 007133 B ATOM 7232 CB THR C 2 -17335 16750 17401 10013335 C ATOM 7148 CA ALA B 442 -7595 1999 61779 1006955 B ATOM 7233 OGl THR C 2 -18325 17655 16900 10013209 C ATOM 7149 CB ALA B 442 -8371 2578 60608 1003399 B ATOM 7234 CG2 THR C 2 -16943 17164 18813 10013524 C ATOM 7150 C ALA B 442 -8363 0846 62396 1006554 B ATOM 7235 C THR C 2 15101 15748 17031 10020007 C ATOM 7151 O ALA B 442 -8819 -0031 61678 1006295 B ATOM 7236 O THR C 2 -15464 14595 17265 10020007 C ATOM 7152 N GLN B 443 -8500 0842 63723 1006128 B ATOM 7237 N PRO C 3 -13833 16154 17247 10019599 C ATOM 7153 CA GLN B 443 -9222 -0227 64413 1006456 B ATOM 7238 CD PRO C 3 -13112 17401 16935 1008277 C ATOM 7154 CB GLN B 443 -8339 -0881 65472 1009032 B ATOM 7239 CA PRO C 3 -12922 15150 17800 10019599 C ATOM 7155 CG GLN B 443 -7534 -2055 64964 1007355 B ATOM 7240 CB PRO C 3 -11708 15981 18213 1008101 C ATOM 7156 CD GLN B 443 -7067 -2953 66100 1007355 B ATOM 7241 CG PRO C 3 -11642 16983 17103 1008088 C ATOM 7157 OEl GLN B 443 -7863 -3361 66952 1007355 B ATOM 7242 C PRO C 3 -13623 14462 18972 10019599 C ATOM 7158 NE2 GLN B 443 -5776 -3269 66117 1007355 B ATOM 7243 O PRO C 3 -13444 13265 19192 10019599 C ATOM 7159 C GLN B 443 10509 0240 65068 1006673 B ATOM 7244 N SER C 4 -14440 15233 19696 10012711 C ATOM 7160 O GLN B 443 -10626 1392 65500 1006779 B ATOM 7245 CA SER C 4 -15226 14731 20825 10012368 C ATOM 7161 N VAL B 444 -11476 -0667 65138 1006059 B ATOM 7246 CB SER C 4 -14460 13658 21 611 10011949 C ATOM 7162 CA VAL B 444 -12761 -0355 65748 1005774 B ATOM 7247 OG SER C 4 -13558 14236 22535 10012144 C ATOM 7163 CB VAL B 444 -13908 -0880 64882 1007438 B ATOM 7248 C SER C 4 ■15678 15808 21809 10012402 C ATOM 7164 CGl VAL B 444 -15219 -0225 65293 1006668 B ATOM 7249 O SER C 4 -16748 15678 22402 10012417 C ATOM 7165 CG2 VAL B 444 -13604 -0603 63425 1006668 B ATOM 7250 N ASP C 5 -14867 16856 21975 1006106 C ATOM 7166 C VAL B 444 -12847 -0971 67151 1006156 B ATOM 7251 CA ASP C 5 -15139 17957 22918 10061 17 C ATOM 7167 O VAL B 444 -12361 -2085 67376 1006382 B ATOM 7252 CB ASP C 5 -16604 17918 23376 10014550 C ATOM 7168 N TYR B 445 -13441 0232 68091 1006103 B ATOM 7253 CG ASP C 5 -16934 18987 24389 10014550 C ATOM 7169 CA TYR B 445 -13579 -0689 69474 1006010 B ATOM 7254 ODl ASP C 5 -18045 18929 24956 10014550 C ATOM 7170 CB TYR B 445 -12553 0008 70358 1008274 B ATOM 7255 OD2 ASP C 5 -16096 19883 24615 10014406 C ATOM 7171 CG TYR B445 -11134 -0245 69922 1005516 B ATOM 7256 C ASP C 5 ^■ 14199 17850 24146 1005867 C 65251/C766

ATOM 7257 O ASPC 5 -13945 18831 24845 1006218 C ATOM 7342 C ALAC 17 16623 16253 16623 1009732 C ATOM 7258 N LYSC 6 -13684 16645 24387 1006412 C ATOM 7343 O ALAC 17 16448 15968 17807 1009896 C ATOM 7259 CA LYSC 6 -12773 16357 25498 1006050 C ATOM 7344 N GLUC 18 17608 15747 15892 1008980 C ATOM 7260 CB LYS C -12629 14852 25712 1005366 C ATOM 7345 CA GLUC 18 18561 14793 16440 1009180 C ATOM 7261 CG LYSC -13806 14094 26271 1006007 C ATOM 7346 CB GLUC 18 19701 14566 15446 10012596 C ATOM 7262 CD LYSC -13489 12591 26211 1006368 C ATOM 7347 CG GLUC 18 20502 15820 15134 10012596 C ATOM 7263 CE LYSC -14520 1175926948 1006695 C ATOM 7348 CD GLUC 18 21705 15533 14260 10012596 C ATOM 7264 NZ LYS C -14544 1209428400 1006814 C ATOM 7349 OEl GLUC 18 22584 14761 14696 10012596 C ATOM 7265 C LYSC 6 -11362 16849 25234 1005583 C ATOM 7350 OE2GLUC 18 21771 16077 13138 10012596 C ATOM 7266 O LYS C 6 -10818 16621 24153 1005971 C ATOM 7351 C GLUC 18 19148 15241 17776 009146 C ATOM 7267 N PRO C 7 -10741 17530 26207 1005363 C ATOM 7352 O GLU C 18 19309 16437 18036 009107 C ATOM 7268 CD PROC 7 -11241 18146 27441 1003457 C ATOM 7353 N GLYC 19 19459 14261 18619 009398 C ATOM 7269 CA PRO C 7 -9371 17969 25929 1005167 C ATOM 7354 CA GLYC 19 20054 14542 19911 1009147 C ATOM 7270 CB PROC 7 -8978 18749 27190 1003657 C ATOM 7355 C GLYC 19 19118 15009 21003 1008997 C ATOM 7271 CG PROC 7 -9961 18319 28218 1003544 C ATOM 7356 O GLYC 19 19527 15108 22155 1008998 C ATOM 7272 C PROC 7 -8541 16706 25730 1004973 C ATOM 7357 N GLN C 20 17867 1529720663 1009473 C ATOM 7273 O PROC 7 -8666 15748 26488 1005074 C ATOM 7358 CA GLNC 20 16916 15758 21667 1009030 C ATOM 7274 N VAL C 8 -7712 16696 24699 1002808 C ATOM 7359 CB GLNC 20 16853 1728021548 10011459 C ATOM 7275 CA VALC 8 -6909 15525 24403 1002924 C ATOM 7360 CG GLNC 20 16556 1784620281 10011557 C ATOM 7276 CB VALC 8 -7725 14526 23504 1003042 C ATOM 7361 CD GLNC 20 16571 1936020269 10011533 C ATOM 7277 CGl VALC 8 8163 1522422219 1003100 C ATOM 7362 OEl GLN C 20 17584 19981 20593 10011498 C ATOM 7278 CG2VALC 8 -6900 1330023161 1003312 C ATOM 7363 NE2GLNC 20 15445 19966 19897 10011478 C ATOM 7279 C VALC 8 -5637 15922 23663 1003174 C ATOM 7364 C GLN C 20 15519 15179 21476 1008504 C ATOM 7280 O VALC 8 -5541 17011 23097 1003098 C ATOM 7365 O GLN C 20 15225 14553 20453 1008375 C ATOM 7281 N ALAC 9 4660 15026 23661 1003853 C ATOM 7366 N LEU C 21 14662 15391 22471 1005903 C ATOM 7282 CA ALA C 9 -3434 15293 22943 1004477 C ATOM 7367 CA LEUC 21 13296 14887 22420 1005549 C ATOM 7283 CB ALAC 9 -2642 1637623640 1004611 C ATOM 7368 CB LEUC 21 13006 14017 23643 1005315 C ATOM 7284 C ALAC 9 -2602 14041 22828 1004575 C ATOM 7369 CG LEUC 21 11597 13447 23804 1005193 C ATOM 7285 O ALAC 9 -2485 13266 23781 1004373 C ATOM 7370 CDl LEUC 21 11141 12792 22502 1004923 C ATOM 7286 N HISC 10 -2051 1383621641 I 003978 C ATOM 7371 CD2LEUC 21 U 589 1244724956 1005397 C ATOM 7287 CA HIS C 10 -1 166 1270721388 1004065 C ATOM 7372 C LEUC 21 12318 16039 22366 1005410 C ATOM 7288 CB HIS C 10 -1874 11593 20618 1003761 C ATOM 7373 O LEU C 21 11900 16553 23398 1004942 C ATOM 7289 CG HIS C 10 -1012 10389 20380 1003910 C ATOM 7374 N GLN C 22 11954 16442 21156 1006598 C ATOM 7290 CD2HISC 10 -0301 10004 19294 1003683 C ATOM 7375 CA GLNC 22 11026 17546 20961 1007058 C ATOM 7291 NDl HISC 10 -0759 9446 21355 1003924 C ATOM 7376 CB GLN C 22 II 634 18516 19957 1007486 C ATOM 7292 CElHISC 10 0074 8536 20881 1003959 C ATOM 7377 CG GLNC 22 10721 19620 19497 1008163 C ATOM 7293 NE2 HIS C 10 0368 8852 19631 1003707 C ATOM 7378 CD GLNC 22 11273 20334 18279 1008785 C ATOM 7294 C HIS C 10 -0063 1329020531 1003886 C ATOM 7379 OEl GLN C 22 1060621185 17690 1009308 C ATOM 7295 O HISC 10 -0217 13430 19319 1003702 C ATOM 7380 NE2 GLN C 22 12499 19990 17893 1008861 C ATOM 7296 N VALC 11 1037 13670 21160 1004946 C ATOM 7381 C GLNC 22 9678 17010 20460 1006797 C ATOM 7297 CA VALC 11 2141 1426020423 1005204 C ATOM 7382 O GLN C 22 9621 16294 19464 1006692 C ATOM 7298 CB VALC 11 2713 1547021155 1003664 C ATOM 7383 N TRPC 23 8596 17361 21151 1004670 C ATOM 7299 CGl VALC 11 I 629 16523 21290 1003270 C ATOM 7384 CA TRP C 23 7263 1688720786 1004058 C ATOM 7300 CG2VALC Il 3240 15055 22538 1003862 C ATOM 7385 CB TRP C 23 6360 16801 22024 1004259 C ATOM 7301 C VALC 11 3216 13226 20211 1005065 C ATOM 7386 CG TRP C 23 6893 1597723149 1004311 C ATOM 7302 O VALC 11 3367 1228520992 I 004766 C ATOM 7387 CD2TRPC 23 7070 14553 23168 1004122 C ATOM 7303 N VALC 12 3966 13407 19141 1004856 C ATOM 7388 CE2TRPC 23 7604 14216 24437 1004284 C ATOM 7304 CA VALC 12 4998 12464 18793 1004673 C ATOM 7389 CE3TRPC 23 6832 13528 22238 1004091 C ATOM 7305 CB VALC 12 4605 11790 17476 1005863 C ATOM 7390 CDl TRP C 23 7312 16431 24364 1004258 C ATOM 7306 CGlVALC 12 4788 12754 16340 1005243 C ATOM 7391 NEl TRPC 23 7740 15379 25147 1004167 C ATOM 7307 CG2 VAL C 12 5392 10518 17273 1006210 C ATOM 7392 CZ2TRPC 23 7903 1289724798 1004490 C ATOM 7308 C VALC 12 6359 13169 18690 1004469 C ATOM 7393 CZ3 TRP C 23 7129 12213 22601 1004535 C ATOM 7309 O VALC 12 6431 14397 18578 1004453 C ATOM 7394 CH2 TRP C 23 7659 1191423870 1004316 C ATOM 7310 N ALAC 13 7434 12391 18750 I 005214 C ATOM 7395 C TRPC 23 6543 17754 19765 1004108 C ATOM 7311 CA ALAC 13 8788 12929 18692 1005181 C ATOM 7396 O TRPC 23 6570 18982 19857 1004236 C ATOM 7312 CB ALAC 13 9775 11889 19191 1003722 C ATOM 7397 N LEUC 24 5893 17115 18796 1003890 C ATOM 7313 C ALAC 13 9200 13390 17306 1005579 C ATOM 7398 CA LEU C 24 5130 17868 17816 1003659 C ATOM 7314 O ALAC 13 8909 12727 16309 1005330 C ATOM 7399 CB LEU C 24 5792 17895 16430 1006251 C ATOM 7315 N ASNC 14 9896 14525 17262 1004838 C ATOM 7400 CG LEU C 24 7235 17493 16208 1006324 C ATOM 7316 CA ASNC 14 10386 15114 16019 1004950 C ATOM 7401 CDl LEU C 24 7341 15995 16353 1006486 C ATOM 7317 CB ASNC 14 10631 16605 16224 1007427 C ATOM 7402 CD2LEUC 24 7665 17902 14824 1005835 C ATOM 7318 CG ASNC 14 11137 17291 14974 1007626 C ATOM 7403 C LEUC 24 3757 17254 17675 1004345 C ATOM 7319 ODlASNC 14 II 447 18483 14997 1007584 C ATOM 7404 O LEUC 24 3542 16088 18007 1004043 C ATOM 7320 ND2 ASN C 14 11218 16546 13872 1007838 C ATOM 7405 N ASNC 25 2830 18054 17167 1004815 C ATOM 7321 C ASNC 14 11690 14441 15618 1005238 C ATOM 7406 CA ASN C 25 1473 17604 16961 1004959 C ATOM 7322 O ASNC 14 12696 14564 16323 1005290 C ATOM 7407 CB ASN C 25 0537 18439 17821 1004481 C ATOM 7323 N PROC 15 11699 13731 14474 1006774 C ATOM 7408 CG ASN C 25 0376 19839 17294 1004638 C ATOM 7324 CD PROC 15 10597 13499 13525 1003413 C ATOM 7409 ODl ASN C 25 -0713 20226 16858 1005037 C ATOM 7325 CA PROC 15 12920 13049 14023 1007134 C ATOM 7410 ND2ASNC 25 146420611 17317 1004278 C ATOM 7326 CB PROC 15 12418 12098 12928 1003847 C ATOM 7411 C ASNC 25 1086 17766 15495 1005012 C ATOM 7327 CG PROC 15 10901 12108 13061 1003674 C ATOM 7412 O ASNC 25 -0016 17399 15100 1005248 C ATOM 7328 C PROC 15 13961 14020 13476 1007255 C ATOM 7413 N ARGC 26 1986 18317 14688 1005730 C ATOM 7329 O PROC 15 15145 13715 13433 1007458 C ATOM 7414 CA ARGC 26 1692 18547 13279 1005858 C ATOM 7330 N GLNC 16 13500 15191 13061 1009737 C ATOM 7415 CB ARGC 26 2452 19776 12776 1004345 C ATOM 7331 CA GLNC 16 14373 16201 12487 1009632 C ATOM 7416 CG ARGC 26 3944 19722 13000 1004436 C ATOM 7332 CB GLNC 16 13532 17183 Il 659 10012405 C ATOM 7417 CD ARGC 26 463020821 12230 1004842 C ATOM 7333 CG GLNC 16 14307 17990 10623 10012698 C ATOM 7418 NE ARGC 26 607520817 12424 1004956 C ATOM 7334 CD GLNC 16 15011 17110 9602 10012877 C ATOM 7419 CZ ARGC 26 6689 21378 13461 1005012 C ATOM 7335 OElGLNC 16 14441 16136 9111 10013089 C ATOM 7420 NHl ARG C 26 598721995 14402 1005060 C ATOM 7336 NE2GLNC 16 16252 17459 9269 10012742 C ATOM 7421 NH2ARGC 26 801021317 13559 1004915 C ATOM 7337 C GLNC 16 15166 16955 13557 1009299 C ATOM 7422 C ARGC 26 2009 17365 12384 1005664 C ATOM 7338 O GLNC 16 15925 17876 13248 1009356 C ATOM 7423 O ARG C 26 2615 17530 11324 1005635 C ATOM 7339 N ALAC 17 14996 16565 14815 1008906 C ATOM 7424 N ARG C 27 1595 16172 12797 1004367 C ATOM 7340 CA ALAC 17 15704 17229 15906 1009282 C ATOM 7425 CA ARG C 27 1859 14988 11996 1004460 C ATOM 7341 CB ALAC 17 14706 17828 16888 1003949 C ATOM 7426 CB ARG C 27 2995 14173 12611 1004871 C 65251/C766

ATOM 7427 CG ARG C 27 4 325 14 870 12 553 1 00 50 13 C ATOM 7512 CB ARG C 39 3304 25883 26443 1005755 C ATOM 742S CD ARG C 27 4 616 15 325 11 140 1 00 52 50 C ATOM 7513 CG ARG C 39 3847 27244 26692 1006525 C ATOM 7429 NE ARG C 27 5 844 16 112 11 036 1 00 55 89 C ATOM 7514 CD ARG C 39 2816 28070 27434 1007386 C ATOM 7430 CZ ARG C 27 7061 15 647 1 1 315 1 00 59 50 C ATOM 7515 NE ARG C 39 3174 29484 27416 1008039 C ATOM 7431 NHl ARG C 27 8 119 16444 11 188 1 00 6037 C ATOM 7516 CZ ARG C 39 2351 30469 27763 10081 19 C ATOM 7432 NH2 ARG C 27 7223 14 385 11 722 1 00 5773 C ATOM 7517 NHl ARG C 39 1 116 30191 28159 1007967 C ATOM 7433 C ARG C 27 0 649 14 096 11 769 1 0045 06 C ATOM 7518 NH2 ARG C 39 2756 31734 27704 1008349 C ATOM 7434 O ARG C 27 -0434 14 332 12 311 1 0045 20 C ATOM 7519 C ARG C 39 5446 24618 26098 1005316 C ATOM 7435 N ALA C 28 0 879 13 074 10 948 1 0079 27 C ATOM 7520 O ARG C 39 5506 23807 27022 1005639 C ATOM 7436 CA ALA C 28 0 104 12 079 10 561 1 00 78 17 C ATOM 7521 N ASP C 40 6521 25198 25584 1005102 C ATOM 7437 CB ALA C 28 0 601 10 773 10 235 1 00131 19 C ATOM 7522 CA ASP C 40 7862 24903 26076 1004897 C ATOM 7438 C ALA C 28 -1 212 11 814 11 559 1 0077 83 C ATOM 7523 CB ASP C 40 8085 25581 27425 1009016 C ATOM 7439 O ALA C 28 -2 294 12 390 11 470 1 0078 85 C ATOM 7524 CG ASP C 40 7826 27078 27373 1009230 C ATOM 7440 N ASN C 29 -0 955 10934 12 513 1 0046 48 C ATOM 7525 ODl ASP C 40 8417 27755 26504 1008918 C ATOM 7441 CA ASN C 29 -2 000 10598 13 469 1 00 45 65 C ATOM 7526 OD2 ASP C 40 7031 27582 28198 1009242 C ATOM 7442 CB ASN C 29 -2 184 9 083 13 498 1 00 5009 C ATOM 7527 C ASP C 40 8088 23395 26194 1004510 C ATOM 7443 CG ASN C 29 -2 648 8 529 12 162 1 00 50 15 C ATOM 7528 O ASP C 40 8716 22933 27136 1004433 C ATOM 7444 ODl ASN C 29 -3 836 8 588 11 825 1 00 56 01 C ATOM 7529 N ASN C 41 7557 22637 25235 1004389 C ATOM 7445 ND2 ASN C 29 -1 704 8 000 1 1 387 1 00 47 16 C ATOM 7530 CA ASN C 41 7696 21 182 25175 1003964 C ATOM 7446 C ASN C 29 -1 705 11 125 14 858 1 00 43 99 C ATOM 7531 CB ASN C 41 9173 20786 25220 1006033 C ATOM 7447 O ASN C 29 -1 602 10361 15 809 1 0041 71 C ATOM 7532 CG ASN C 41 9443 19456 24535 1005502 C ATOM 7448 N ALA C 30 -1 572 12441 14964 1 003732 C ATOM 7533 ODl ASN C 41 9098 19264 23368 1005636 C ATOM 7449 CA ALA C 30 1 283 13 089 16 231 1 00 32 14 C ATOM 7534 ND2 ASN C 41 10068 18536 25253 10051 12 C ATOM 7450 CB ALA C 30 0016 13 893 16 119 1 00 33 14 C ATOM 7535 C ASN C 41 6937 20432 26261 1004295 C ATOM 7451 C ALA C 30 -2 450 13 981 16 621 1 00 33 54 C ATOM 7536 O ASN C 41 7285 19302 26611 1004446 C ATOM 7452 O ALA C 30 3 334 14 253 15 798 1 0037 69 C ATOM 7537 N GLN C 42 5892 21056 26789 1004984 C ATOM 7453 N LEU C 31 -2 456 14429 17 S74 1 00 40 27 C ATOM 7538 CA GLN C 42 5096 20429 27830 1004776 C ATOM 7454 CA LEU C 31 -3 544 15 258 18 365 1 00 39 74 C ATOM 7539 CB GLN C 42 5359 21087 29183 1004052 C ATOM 7455 CB LEU C 31 -4582 14 388 19 060 1 0039 42 C ATOM 7540 CG GLN C 42 6816 21249 29505 1004261 C ATOM 7456 CG LEU C 31 -5 500 13 485 18257 1 004230 C ATOM 7541 CD GLN C 42 7048 21980 30816 1004207 C ATOM 7457 CDl LEU C 31 -6 184 12 516 19 197 1 00 39 92 C ATOM 7542 OEl GLN C 42 6447 23030 31084 1004150 C ATOM 7458 CD2 LEU C 31 -6 511 14 322 17 523 1 00 41 77 C ATOM 7543 NE2 GLN C 42 7940 21435 31635 1004383 C ATOM 7459 C LEU C 31 -3 124 16 328 19 352 1 00 39 00 C ATOM 7544 C GLN C 42 3637 20595 27481 1004665 C ATOM 7460 O LEU C 31 -2 193 16 139 20 130 1 00 39 81 C ATOM 7545 O GLN C 42 3250 21586 26861 1004699 C ATOM 7461 N LEU C 32 -3 855 17436 19 330 1 00 51 05 C ATOM 7546 N LEU C 43 2826 19623 27875 1003915 C ATOM 7462 CA LEU C 32 -3 647 18 557 20 233 1 00 50 84 C ATOM 7547 CA LEU C 43 1400 19698 27615 1003773 C ATOM 7463 CB LEU C 32 -2442 19 395 19 810 1 0043 32 C ATOM 7548 CB LEU C 43 0808 18281 27533 1003038 C ATOM 7464 CG LEU C 32 -2 159 20519 20 807 1 0041 90 C ATOM 7549 CG LEU C 43 1326 17440 26373 1003654 C ATOM 7465 CDl LEU C 32 -1 721 19 895 22 131 1 0040 88 C ATOM 7550 CDl LEU C 43 0848 16021 26494 1003663 C ATOM 7466 CD2 LEU C 32 -1 087 21 436 20 274 1 00 42 22 C ATOM 7551 CD2 LEU C 43 0863 18067 25071 1003293 C ATOM 7467 C LEU C 32 -4914 19 376 20 101 1 00 50 48 C ATOM 7552 C LEU C 43 0776 20495 28766 1003975 C ATOM 7468 O LEU C 32 -4 959 20340 19 345 1 00 56 35 C ATOM 7553 O LEU C 43 1 138 20309 29930 1003637 C ATOM 7469 N ALA C 33 -5 946 18997 20 842 1 00 29 32 C ATOM 7554 N VAL C 44 -0150 21389 28450 1003375 C ATOM 7470 CA ALA C 33 7223 19 686 20 734 1 00 29 84 C ATOM 7555 CA VAL C 44 -0784 22176 29494 1003343 C ATOM 7471 CB ALA C 33 -8 116 18 911 19 814 1 00 31 53 C ATOM 7556 CB VAL C 44 -0540 23659 29280 1003217 C ATOM 7472 C ALA C 33 -7995 20004 21 997 1 0031 63 C ATOM 7557 CGl VALC 44 -1061 24425 30460 1003336 C ATOM 7473 O ALA C 33 -7 655 19 594 23 105 1 00 35 81 C ATOM 7558 CG2 VAL C 44 0943 23912 29062 1002678 C ATOM 7474 N ASN C 34 -9 064 20755 21 787 1 00 47 19 C ATOM 7559 C VAL C 44 -2286 21919 29550 1003244 C ATOM 7475 CA ASN C 34 -9 960 21 158 22 846 I 004438 C ATOM 7560 O VAL C 44 -3010 22149 28581 1003348 C ATOM 7476 CB ASN C 34 -10 797 19967 23 272 1 00 57 33 C ATOM 7561 N VAL C 45 -2739 21433 30703 1003865 C ATOM 7477 CG ASN C 34 -11 591 19415 22 133 1 00 61 25 C ATOM 7562 CA VAL C 45 -4135 21094 30925 1004439 C ATOM 7478 ODl ASN C 34 -12 275 20 159 21 430 1 0063 73 C ATOM 7563 CB VAL C 45 -4274 20260 32212 1005222 C ATOM 7479 ND2 ASN C 34 -11 508 18 107 21 930 1 0056 66 C ATOM 7564 CGl VAL C 45 -5721 20136 32603 1005479 C ATOM 7480 C ASN C 34 -9 342 21 810 24 064 1 00 45 13 C ATOM 7565 CG2 VAL C 45 -3697 18881 31986 1005562 C ATOM 7481 O ASN C 34 -9 741 21 525 25 195 1 00 47 67 C ATOM 7566 C VAL C 45 5012 22336 31002 1004618 C ATOM 7482 N GLY C 35 -8 371 22 686 23 835 1 00 49 66 C ATOM 7567 O VAL C 45 -4687 23290 31 692 1004563 C ATOM 7483 CA GLY C 35 -7 773 23 390 24 947 1 00 4425 C ATOM 7568 N PRO C 46 -6147 22329 30285 1004092 C ATOM 7484 C GLY C 35 -6 376 23 046 25 402 1 00 44 60 C ATOM 7569 CD PRO C 46 -6475 21359 29219 1002872 C ATOM 7485 O GLY C 35 -5 659 23 931 25 857 1 00 46 09 C ATOM 7570 CA PRO C 46 -7082 23461 30264 1003977 C ATOM 7486 N VAL C 36 -5 966 21 792 25 323 1 00 36 54 C ATOM 7571 CB PRO C 46 -7645 23408 28856 1002808 C ATOM 7487 CA VALC 36 -4 620 21 506 25 784 1 00 37 87 C ATOM 7572 CG PRO C 46 -7773 21927 28636 1002878 C ATOM 7488 CB VAL C 36 -4 367 19 968 25 958 1 00 38 93 C ATOM 7573 C PRO C 46 -8198 23453 31286 1004321 C ATOM 7489 CGl VAL C 36 -5 512 19 184 25 390 1 00 36 96 C ATOM 7574 O PRO C 46 -8947 24415 31358 1004567 C ATOM 7490 CG2 VAL C 36 3 060 19 561 25 327 1 00 39 33 C ATOM 7575 N SER C 47 -8341 22384 32062 1004617 C ATOM 7491 C VAL C 36 -3 616 22 163 24 841 1 00 42 02 C ATOM 7576 CA SER C 47 -9421 22337 33049 1004329 C ATOM 7492 O VAL C 36 -3 791 22 173 23 625 1 00 42 98 C ATOM 7577 CB SER C 47 -10747 22081 32340 1006097 C ATOM 7493 N GLU C 37 2 575 22 743 25 426 1 00 51 77 C ATOM 7578 OG SER C 47 -10710 20833 31664 1006218 C ATOM 7494 CA GLU C 37 -1 563 23 432 24 656 1 00 5437 C ATOM 7579 C SER C 47 -9247 21290 34148 1003998 C ATOM 7495 CB GLU C 37 -1 459 24 878 25 132 1 006820 C ATOM 7580 O SER C 47 -8516 20314 33966 1003712 C ATOM 7496 CG GLU C 37 -2 802 25 484 25 475 1 0075 23 C ATOM 7581 N GLU C 48 -9921 21513 35284 1002883 C ATOM 7497 CD GLU C 37 -2 689 26 777 26 269 1 007820 C ATOM 7582 CA GLU C 48 -9897 20593 36422 1003332 C ATOM 7498 OEl GLU C 37 -1 698 26938 27 024 1 00 81 63 C ATOM 7583 CB GLU C 48 -10882 21042 37502 10016261 C ATOM 7499 OE2 GLU C 37 -3 606 27 625 26 155 1 00 78 76 C ATOM 7584 CG GLU C 48 -10690 22454 38025 10016735 C ATOM 7500 C GLU C 37 -0220 22 758 24 807 1 00 53 26 C ATOM 7585 CD GLU C 48 -9618 22551 39094 10017170 C ATOM 7501 O GLU C 37 0045 22 105 25 807 1 00 55 72 C ATOM 7586 OEl GLU C 48 -8425 22382 38766 10017344 C ATOM 7502 N LEU C 38 0619 22 909 23 791 1 00 61 71 C ATOM 7587 OE2 GLU C 48 -9971 22792 40269 10016962 C ATOM 7503 CA LEU C 38 1 958 22352 23 822 1 0063 75 C ATOM 7588 C GLU C 48 -10373 19239 35878 1003191 C ATOM 7504 CB LEU C 38 2 262 21 609 22 520 1 00 35 53 C ATOM 7589 O GLU C 48 -11 146 19191 34916 1003770 C ATOM 7505 CG LEU C 38 3 609 20 892 22459 1 0033 44 C ATOM 7590 N GLY C 49 -9907 18141 36467 1003547 C ATOM 7506 CDl LEU C 38 3 802 20 073 23 727 1 0031 82 C ATOM 7591 CA GLY C 49 -10364 16853 36002 1003313 C ATOM 7507 CD2 LEU C 38 3 671 20 013 21 219 1 003031 C ATOM 7592 C GLY C 49 -9426 15683 36139 1003514 C ATOM 7508 C LEU C 38 2 816 23 599 23 954 1 006402 C ATOM 7593 O GLY C 49 -8271 15812 36521 1003798 C ATOM 7509 O LEU C 38 3 002 24 338 22 991 1 00 57 63 C ATOM 7594 N LEU C 50 -9969 14520 35826 1004761 C ATOM 7510 N ARG C 39 3 307 23 835 25 165 1 0044 58 C ATOM 7595 CA LEU C 50 -9248 13262 35854 1004881 C ATOM 7511 CA ARG C 39 4 105 25 013 25479 1 0051 11 C ATOM 7596 CB LEU C 50 -10238 12141 36179 1003833 C 65251/C766

ATOM 7597 CG LEU C 50 10 142 11 365 37493 1 00 39 46 C ATOM 7682 O PHE C 59 16235 1366 22080 1006472 C ATOM 7598 CDl LEU C 50 -9 557 12217 38 567 1 00 36 27 C ATOM 7683 N LYS C 60 17719 2960 21520 1007456 C ATOM 7599 CD2 LEU C 50 -11 509 10 870 37 889 1 00 39 85 : C ATOM 7684 CA LYS C 60 18488 2105 20628 1007591 C ATOM 7600 C LEU C 50 -8 671 13 077 34445 1 0045 19 C ATOM 7685 CB LYS C 60 18024 2276 19186 1007243 C ATOM 7601 O LEU C 50 -9 383 13 213 33 455 1 0043 91 C ATOM 7686 CG LYS C 60 18852 1499 18182 1007862 C ATOM 7602 N TYR C 51 -7 382 12 780 34351 1 00 38 45 C ATOM 7687 CD LYS C 60 18389 1798 16765 1008683 C ATOM 7603 CA TYR C 51 6 744 12 589 33 049 1 00 37 10 C ATOM 7688 CE LYS C 60 19213 1047 15730 1008958 C ATOM 7604 CB TYR C 51 -5 774 13 735 32 738 1 00 33 61 C ATOM 7689 NZ LYS C 60 18704 1303 14354 1008992 C ATOM 7605 CG TYR C 51 -641 1 15 058 32 403 1 00 33 71 C ATOM 7690 C LYS C 60 19956 2474 20728 1007542 C ATOM 7606 CDl TYR C 51 -7 007 15 839 33 381 1 00 34 57 C ATOM 7691 O LYS C 60 20312 3653 20762 1007817 C ATOM 7607 CEl TYR C 51 -7 571 17058 33 075 1 00 34 13 C ATOM 7692 N GLY C 61 20808 1459 20778 1008781 C ATOM 7608 CD2 TYR C 51 -6 400 15 531 31 101 I 0035 27 C ATOM 7693 CA GLY C 61 22228 1711 20875 1009037 C ATOM 7609 CE2 TYR C 51 -6 968 16 753 30 777 1 00 33 54 C ATOM 7694 C GLY C 61 23014 0711 20064 1009207 C ATOM 7610 CZ TYRC 51 -7554 17512 31 768 1 00 3324 C ATOM 7695 O GLY C 61 22631 -0458 19975 1009524 C ATOM 7611 OH TYR C 51 -8 138 18 718 31 437 1 00 33 47 C ATOM 7696 N GLN C 62 24103 1177 19459 10011510 C ATOM 7612 C TYR C 51 -5 948 11 301 32 949 1 00 37 28 C ATOM 7697 CA GLN C 62 24965 0315 18660 10011541 C ATOM 7613 O TYR C 51 -5 324 10 851 33 920 1 0038 17 C ATOM 7698 CB GLN C 62 25665 1 124 17567 10012008 C ATOM 7614 N LEU C 52 -5 972 10 706 31 763 1 00 39 66 C ATOM 7699 CG GLN C 62 24723 1867 16631 10012421 C ATOM 7615 CA LEU C 52 -5 200 9 501 31 516 1 0041 31 C ATOM 7700 CD GLN C 62 23857 0936 15806 10013015 C ATOM 7616 CB LEU C 52 -5 935 8 552 30571 I 0040 80 C ATOM 7701 OEl GLN C 62 23089 0141 16344 10012975 C ATOM 7617 CG LEU C 52 -5 077 7 406 30019 1 0036 69 C ATOM 7702 NE2 GLN C 62 23977 1034 14490 10013032 C ATOM 7618 CDl LEU C 52 -4382 6 662 31 143 1 0038 72 C ATOM 7703 C GLN C 62 25997 -0261 19616 10011335 C ATOM 7619 CD2 LEU C 52 -5 961 6 477 29 204 1 00 31 02 C ATOM 7704 O GLN C 62 26739 0486 20255 10011486 C ATOM 7620 C LEU C 52 -3 966 10058 30 846 1 0042 84 C ATOM 7705 N GLY C 63 26028 -1585 19728 1008913 C ATOM 7621 O LEU C 52 -4 075 10 734 29 837 1 00 43 41 C ATOM 7706 CA GLY C 63 26977 -2219 20625 1008712 C ATOM 7622 N ILE C 53 -2 805 9 812 31 439 1 00 45 57 C ATOM 7707 C GLY C 63 26857 -1659 22029 1008520 C ATOM 7623 CA ILE C 53 -1 536 10295 30917 1 0042 17 C ATOM 7708 O GLY C 63 25911 0936 22325 1008324 C ATOM 7624 CB ILE C 53 -0 774 11 078 31 975 1 00 53 82 C ATOM 7709 N CYS C 64 27821 -1968 22890 10011885 C ATOM 7625 CG2 ILE C 53 0 494 11 639 31 383 1 00 54 46 C ATOM 7710 CA CYS C 64 27774 -1491 24267 10012309 C ATOM 7626 CGl ILE C 53 -1 630 12 219 32497 1 005271 C ATOM 7711 C CYS C 64 28842 -0496 24714 10012918 C ATOM 7627 CDl ILE C 53 -0 948 13 036 33 575 1 0048 53 C ATOM 7712 O CYS C 64 30013 -0597 24342 10013209 C ATOM 7628 C ILE C 53 -0 679 9 110 30 526 1 00 42 23 C ATOM 7713 CB CYS C 64 27762 -2681 25223 10017351 C ATOM 7629 O ILE C 53 -0 598 8 125 31 263 1 00 45 31 C ATOM 7714 SG CYS C 64 26109 -3421 25371 10017472 C ATOM 7630 N TYR C 54 -0 024 9 192 29 377 1 00 4454 C ATOM 7715 N PRO C 65 28432 0492 25525 10013820 C ATOM 7631 CA TYR C 54 0 827 8086 28 941 1 0041 67 C ATOM 7716 CD PRO C 65 27027 0862 25768 10016363 C ATOM 7632 CB TYR C 54 -0016 7014 28233 1 0034 38 C ATOM 7717 CA PRO C 65 29328 1526 26047 10014054 C ATOM 7633 CG TYR C 54 -0 659 7 514 26967 1 0034 38 C ATOM 7718 CB PRO C 65 28363 2569 26615 10016616 C ATOM 7634 CDl TYR C 54 0002 7430 25 755 1 003438 C ATOM 7719 CG PRO C 65 27111 236025818 10016589 C ATOM 7635 CEl TYR C 54 0546 7 959 24 594 1 003438 C ATOM 7720 C PRO C 65 30249 0968 27121 10014355 C ATOM 7636 CD2 TYR C 54 -1 903 8 140 26 991 1 00 3438 C ATOM 7721 O PRO C 65 30579 -0218 27122 10014382 C ATOM 7637 CE2 TYR C 54 -2465 8 671 25 826 1 00 34 38 C ATOM 7722 N SER C 66 30650 1838 28039 10013954 C ATOM 7638 CZ TYR C 54 1 779 8 577 24 636 1 00 34 38 C ATOM 7723 CA SER C 66 31527 1453 29130 10014314 C ATOM 7639 OH TYR C 54 -2 327 9 115 23 492 1 003438 C ATOM 7724 CB SER C 66 32541 256729397 10014832 C ATOM 7640 C TYR C 54 1 967 8 541 28 025 1 004026 C ATOM 7725 OG SER C 66 33394 2238 30478 10014548 C ATOM 7641 O TYR C 54 1 951 9 631 27 452 1 00 39 11 C ATOM 7726 C SER C 66 30707 118730388 10014369 C ATOM 7642 N SER C 55 2 963 7 683 27 898 1 0045 13 C ATOM 7727 O SER C 66 29487 1363 30396 10013711 C ATOM 7643 CA SER C 55 4 100 7991 27 062 1 00 44 91 C ATOM 7728 N THR C 67 31398 0760 31441 10020084 C ATOM 7644 CB SER C 55 4 963 9 061 27 722 1 00 39 61 C ATOM 7729 CA THR C 67 30792 0457 32737 10020084 C ATOM 7645 OG SER C 55 6 139 9278 26 963 1 0046 17 C ATOM 7730 CB THR C 67 30905 1664 33702 10018127 C ATOM 7646 C SER C 55 4 955 6761 26 797 1 00 47 89 C ATOM 7731 OGl THR C 67 32271 2089 33778 10018127 C ATOM 7647 O SER C 55 5 022 5 844 27 618 1 0045 03 C ATOM 7732 CG2 THR C 67 30427 1279 35103 10018127 C ATOM 7648 N GLN C 56 5 597 6 746 25 634 1 0052 83 C ATOM 7733 C THR C 67 29326 0038 32662 10020084 C ATOM 7649 CA GLN C 56 6481 5 656 25 284 1 00 53 53 C ATOM 7734 O THR C 67 29013 -1119 32377 10020084 C ATOM 7650 CB GLN C 56 5 805 4 625 24395 1 00 45 51 C ATOM 7735 N HIS C 68 28433 0991 32913 10014519 C ATOM 7651 CG GLN C 56 6722 3 439 24 176 1 00 47 11 C ATOM 7736 CA HIS C 68 27005 0714 32902 10014031 C ATOM 7652 CD GLN C 56 6294 2 537 23 051 1 00 50 23 C ATOM 7737 CB HIS C 68 26570 0275 34305 10020084 C ATOM 7653 OEl GLN C 56 6 548 2 821 21 881 1 0049 76 C ATOM 7738 CG HIS C 68 25303 -0521 34329 10020084 C ATOM 7654 NE2 GLN C 56 5 635 1 437 23 396 1 00 53 34 C ATOM 7739 CD2 HIS C 68 24115 -0290 34937 10020084 C ATOM 7655 C GLN C 56 7695 6 170 24548 1 00 5601 C ATOM 7740 NDl HIS C 68 25173 -1730 33681 10020084 C ATOM 7656 O GLN C 56 7 587 7 004 23 645 1 005409 C ATOM 7741 CEl HIS C 68 23960 -2210 33889 i 0020084 C ATOM 7657 N VAL C 57 8 858 5 674 24 945 1 0053 90 C ATOM 7742 NE2 HIS C 68 23298 -1355 34648 10020084 C ATOM 7658 CA VAL C 57 10095 6 050 24287 1 0048 27 C ATOM 7743 C HIS C 68 26223 1954 32475 10013614 C ATOM 7659 CB VAL C 57 11 033 6 831 25 216 1 00 52 02 C ATOM 7744 O HIS C 68 26584 3078 32821 10013559 C ATOM 7660 CGl VAL C 57 10 338 8 079 25 704 1 00 53 22 C ATOM 7745 N VAL C 69 25155 1742 31715 1008675 C ATOM 7661 CG2 VAL C 57 11 474 5 955 26 376 1 00 48 95 C ATOM 7746 CA VAL C 69 24315 2841 31252 1008648 C ATOM 7662 C VAL C 57 10 766 4 750 23 883 1 00 50 88 C ATOM 7747 CB VAL C 69 24293 292429708 1008723 C ATOM 7663 O VAL C 57 10 565 3 714 24 520 1 00 51 99 C ATOM 7748 CGl VALC 69 23449 4102 29267 1008699 C ATOM 7664 N LEU C 58 11 546 4 806 22 811 1 00 6470 C ATOM 7749 CG2 VAL C 69 25703 3062 29167 1008549 C ATOM 7665 CA LEU C 58 12250 3 633 22333 1 0063 15 C ATOM 7750 C VALC 69 22884 264931750 1008607 C ATOM 7666 CB LEU C 58 11 762 3 251 20940 1 00 56 52 C ATOM 7751 O VALC 69 22331 1552 31678 1008963 C ATOM 7667 CG LEU C 58 11 880 1 783 20545 1 0058 54 C ATOM 7752 N LEU C 70 22293 3719 32267 1008107 C ATOM 7668 CDl LEU C 58 11 882 1 691 19 020 1 0052 56 C ATOM 7753 CA LEU C 70 20924 3659 32763 1007629 C ATOM 7669 CD2 LEU C 58 13 144 1 171 21 124 1 0056 32 C ATOM 7754 CB LEU C 70 20839 4142 34213 1007629 C ATOM 7670 C LEU C 58 13 730 3 978 22 270 1 00 66 12 C ATOM 7755 CG LEU C 70 21478 3275 35298 1007799 C ATOM 7671 O LEU C 58 14 138 4 856 21 509 1 00 6775 C ATOM 7756 CDl LEU C 70 21188 3886 36657 1007303 C ATOM 7672 N PHE C 59 14529 3 298 23 085 1 00 6002 C ATOM 7757 CD2 LEU C 70 20933 1860 35228 1007859 C ATOM 7673 CA PHE C 59 15 964 3 527 23092 1 00 6092 C ATOM 7758 C LEU C 70 20011 451731910 1007733 C ATOM 7674 CB PHE C 59 16 525 3 391 24503 1 00 59 88 C ATOM 7759 O LEU C 70 20352 5648 31563 1007744 C ATOM 7675 CG PHE C 59 16 038 4435 25451 1 00 56 37 C ATOM 7760 N LEU C 71 18852 3966 31573 1007104 C ATOM 7676 CDl PHE C 59 15 072 4 130 26405 1 0054 81 C ATOM 7761 CA LEU C 71 17867 4679 30772 1007098 C ATOM 7677 CD2 PHE C 59 16 564 5 725 25414 1 0058 33 C ATOM 7762 CB LEU C 71 17432 3828 29581 1005938 C ATOM 7678 CEl PHE C 59 14639 5 095 27315 1 00 60 73 C ATOM 7763 CG LEU C 71 18545 341028625 1005705 C ATOM 7679 CE2 PHE C 59 16 139 6 700 26316 1 0061 44 C ATOM 7764 CDl LEU C 71 17995 2464 27567 1005320 C ATOM 7680 CZ PHE C 59 15 176 6 385 27 269 1 00 60 04 C ATOM 7765 CD2 LEU C 71 19139 4643 27986 1005717 C ATOM 7681 C PHEC 59 16657 2 516 22 182 1 006503 C ATOM 7766 C LEUC 71 16669 4961 31660 1007501 C 65251/C766

ATOM 7767 O LEUC 71 16147 4055 32308 1007450 C ATOM 7852 OH TYRC 82 7513 21311 47194 1004288 C ATOM 7768 N THRC 72 16246 6217 31711 1005396 C ATOM 7853 C TYRC 82 404823892 42389 1004653 C ATOM 7769 CA THR C 72 15095 6575 32525 1005139 C ATOM 7854 O TYR C 82 4373 2276042032 1004671 C ATOM 7770 CB THRC 72 15477 7434 33753 1005838 C ATOM 7855 N GLN C 83 4533 25005 41841 1006290 C ATOM 7771 OGlTHRC 72 15746 8781 33348 1006091 C ATOM 7856 CA GLNC 83 548925023 40735 1006279 C ATOM 7772 CG2THRC 72 16697 6864 34432 1005610 C ATOM 7857 CB GLNC 83 5895 2646040409 1007411 C ATOM 7773 C THRC 72 14077 7351 31714 1005402 C ATOM 7858 CG GLNC 83 5172 27114 39247 1007838 C ATOM 7774 O THRC 72 14423 8170 30861 1005506 C ATOM 7859 CD GLNC 83 3791 27572 39614 1007942 C ATOM 7775 N HISC 73 12810 7077 31984 1005067 C ATOM 7860 OEl GLN C 83 3173 2834638888 1007844 C ATOM 7776 CA HIS C 73 11711 775031312 1005112 C ATOM 7861 NE2GLNC 83 3291 27098 40752 1007692 C ATOM 7777 CB HIS C 73 10979 6776 30406 1004739 C ATOM 7862 C GLNC S3 67702422440915 1006097 C ATOM 7778 CG HIS C 73 9900 7410 29595 1005026 C ATOM 7863 O GLNC 83 783624803 41074 1005842 C ATOM 7779 CD2 HIS C 73 9673 870229275 1005202 C ATOM 7864 N THR C 84 6691 2290440873 1006942 C ATOM 7780 NDl HISC 73 8879 668429022 1005487 C ATOM 7865 CA THRC 84 7894 22098 41009 1006179 C ATOM 7781 CEl HIS C 73 8065 7503 28387 1005341 C ATOM 7866 CB THRC 84 8267 2182942456 1007850 C ATOM 7782 NE2HISC 73 8525 8733 28525 1005358 C ATOM 7867 OGl THRC 84 830723059 43182 1007905 C ATOM 7783 C HISC 73 10808 8175 32445 1005020 C ATOM 7868 CG2THRC 84 962921162 42519 1008125 C ATOM 7784 O HIS C 73 10535 7383 33346 1004606 C ATOM 7869 C THRC 84 762920765 40390 1005830 C ATOM 7785 N THRC 74 10348 9417 32431 1004334 C ATOM 7870 O THRC 84 65602018640579 1005961 C ATOM 7786 CA THRC 74 9499 9863 33527 1004993 C ATOM 7871 N LYSC 85 8601 20269 39646 1004296 C ATOM 7787 CB THRC 74 10383 10239 34786 1004590 C ATOM 7872 CA LYSC 85 8447 18980 39023 1004282 C ATOM 7788 OGl THR C 74 9963 11497 35334 1004841 C ATOM 7873 CB LYS C 85 9677 1864438178 1005399 C ATOM 7789 CG2THRC 74 U 858 10306 34419 1005073 C ATOM 7874 CG LYS C 85 9599 19027 36717 1005093 C ATOM 7790 C THRC 74 8562 11009 33162 1004878 C ATOM 7875 CD LYS C 85 10786 18429 35981 1004933 C ATOM 7791 O THRC 74 8939 11923 32444 1004436 C ATOM 7876 CE LYS C 85 10688 18628 34472 1004763 C ATOM 7792 N ILEC 75 7326 10935 33644 1003692 C ATOM 7877 NZ LYS C 85 10660 20056 34077 1004588 C ATOM 7793 CA ILEC 75 6346 11983 33386 1003822 C ATOM 7878 C LYSC 85 8293 1791740103 1004262 C ATOM 7794 CB ILE C 75 4980 11399 32980 1004161 C ATOM 7879 O LYSC 85 9132 17821 40996 1004307 C ATOM 7795 CG2 ILE C 75 3945 12506 32807 1004110 C ATOM 7880 N VALC 86 7205 17151 40041 1004457 C ATOM 7796 CGlILEC 75 5133 10632 31670 1003877 C ATOM 7881 CA VALC 86 6991 16033 40956 1004746 C ATOM 7797 CDl ILE C 75 3838 10068 31152 1004206 C ATOM 7882 CB VALC 86 5824 1626241965 1003755 C ATOM 7798 C ILEC 75 6185 12783 34668 1004136 C ATOM 7883 CGl VALC 86 6129 17469 42843 1004429 C ATOM 7799 O ILEC 75 5850 12229 35716 1003813 C ATOM 7884 CG2 VAL C 86 4528 16475 41246 1003882 C ATOM 7800 N SER C 76 6434 14087 34577 1005038 C ATOM 7885 C VALC 86 6680 14878 40017 1004813 C ATOM 7801 CA SERC 76 6342 14969 35727 1005146 C ATOM 7886 O VALC 86 5847 14996 39121 1005282 C ATOM 7802 CB SERC 76 7605 15822 35851 1006208 C ATOM 7887 N ASNC 87 7382 13772 40189 1005945 C ATOM 7803 OG SERC 76 8754 15013 35929 1007137 C ATOM 7888 CA ASNC 87 7168 12622 39329 1005613 C ATOM 7804 C SERC 76 5167 1590835627 I 004746 C ATOM 7889 CB ASN C 87 8312 1163239522 1006120 C ATOM 7805 O SERC 76 4682 16209 34536 1004361 C ATOM 7890 CG ASNC 87 9631 12182 39053 1006150 C ATOM 7806 N ARG C 77 4719 16371 36785 1004067 C ATOM 7891 ODlASNC 87 9692 13249 38438 1006411 C ATOM 7807 CA ARGC 77 3645 17334 36850 1004585 C ATOM 7892 ND2ASNC 87 10701 11449 39328 1005846 C ATOM 7808 CB ARGC 77 2430 16782 37604 1002554 C ATOM 7893 C ASNC 87 5837 11897 39524 I 005495 C ATOM 7809 CG ARG C 77 1536 17898 38159 1002772 C ATOM 7894 O ASNC 87 5457 11566 40652 1005353 C ATOM 7810 CD ARGC 77 0107 17454 38436 1002859 C ATOM 7895 N LEUC 88 5139 11641 38418 1005075 C ATOM 7811 NE ARG C 77 -0223 17347 39852 1003103 C ATOM 7896 CA LEUC 88 3866 10922 38453 1004974 C ATOM 7812 CZ ARGC 77 -1234 1798740437 1003446 C ATOM 7897 CB LEU C 88 2873 1152637475 1002842 C ATOM 7813 NHl ARG C 77 -1467 17814 41726 1003455 C ATOM 7898 CG LEUC 88 2468 12964 37728 1002535 C ATOM 7814 NH2ARGC 77 -2000 18813 39750 1003432 C ATOM 7899 CDl LEU C 88 1404 13342 36726 1002612 C ATOM 7815 C ARGC 77 4188 18537 37594 1004419 C ATOM 7900 CD2LEUC 88 1971 13119 39181 1002392 C ATOM 7816 O ARGC 77 4850 18396 38615 1004994 C ATOM 7901 C LEUC 88 4091 9483 38054 1004898 C ATOM 7817 N ILEC 78 3949 19720 37057 1004336 C ATOM 7902 O LEUC 88 3568 8570 38667 1004745 C ATOM 7818 CA ILEC 78 4357 20928 37740 1004205 C ATOM 7903 N LEUC 89 4869 9297 37004 1004706 C ATOM 7819 CB ILEC 78 543721773 36925 1004824 C ATOM 7904 CA LEUC 89 5168 7975 36489 1004598 C ATOM 7820 CG2 ILE C 78 6019 20958 35795 1004874 C ATOM 7905 CB LEUC 89 4316 7708 35254 1004563 C ATOM 7821 CGl ILEC 78 4851 23067 36401 1004991 C ATOM 7906 CG LEUC 89 2812 7905 35394 1004961 C ATOM 7822 CDl ILE C 78 461724088 37469 1005023 C ATOM 7907 CDl LEU C 89 2207 805034026 1004934 C ATOM 7823 C ILEC 78 299621600 37892 1004422 C ATOM 7908 CD2LEUC 89 2197 6743 3610! 1004873 C ATOM 7824 O ILEC 78 2432 22138 36940 1004277 C ATOM 7909 C LEUC 89 6639 7946 36105 1004765 C ATOM 7825 N ALAC 79 2450 21495 39100 1004865 C ATOM 7910 O LEUC 89 7157 8908 35531 1004837 C ATOM 7826 CA ALAC 79 1134 22035 39410 1004525 C ATOM 7911 N SERC 90 7310 6845 36404 1003939 C ATOM 7827 CB ALAC 79 0622 21418 40700 1005506 C ATOM 7912 CA SERC 90 8723 6734 36096 1003873 C ATOM 7828 C ALA C 79 107723547 39514 1004645 C ATOM 7913 CB SERC 90 9534 7499 37137 1005848 C ATOM 7829 O ALAC 79 2053 24183 39899 1004665 C ATOM 7914 OG SERC 90 10919 733736909 1006270 C ATOM 7830 N VALC 80 -0083 24112 39181 1004754 C ATOM 7915 C SERC 90 9223 5297 36040 1003736 C ATOM 7831 CA VALC 80 -0274 25552 39251 1005003 C ATOM 7916 O SERC 90 8785 4438 36811 1003718 C ATOM 7832 CB VALC 80 -1663 25976 38729 1005100 C ATOM 7917 N ALAC 91 10147 5034 35123 1003893 C ATOM 7833 CGl VALC 80 -183227471 38856 1004940 C ATOM 7918 CA ALAC 91 10714 3702 35006 1003702 C ATOM 7834 CG2VALC 80 -182825577 37296 1005270 C ATOM 7919 CB ALAC 91 9952 2892 33963 1003490 C ATOM 7835 C VALC 80 -01572599640700 1005458 C ATOM 7920 C ALAC 91 12193 3791 34651 1004099 C ATOM 7836 O VALC 80 030427096 40979 1005317 C ATOM 7921 O ALAC 91 12664 4812 34152 1004286 C ATOM 7837 N SERC 81 -05662513741624 1006888 C ATOM 7922 N ILEC 92 12920 2718 34928 1004845 C ATOM 7838 CA SERC 81 -0502 2548243034 1007174 C ATOM 7923 CA ILEC 92 14347 2656 34654 1004843 C ATOM 7839 CB SERC 81 -1706 24899 43763 I 006303 C ATOM 7924 CB ILEC 92 15157 2697 35961 1004643 C ATOM 7840 OG SERC 81 -290625485 43290 1006607 C ATOM 7925 CG2 ILE C 92 16629 2779 35648 1005250 C ATOM 7841 C SERC 81 0778 25038 43726 1007592 C ATOM 7926 CGl ILEC 92 14742 3909 36793 1004454 C ATOM 7842 O SERC 81 0875 2513644947 1007644 C ATOM 7927 CDl ILE C 92 15366 3958 38154 1005041 C ATOM 7843 N TYRC 82 1755 2455442957 1004506 C ATOM 7928 C ILEC 92 14647 1347 33935 1004826 C ATOM 7844 CA TYRC 82 3039 24095 43515 1004710 C ATOM 7929 O ILEC 92 13989 0331 34182 1004934 C ATOM 7845 CB TYR C 82 28592278044277 1003701 C ATOM 7930 N LYS C 93 15633 1364 33047 1006738 C ATOM 7846 CG TYRC 82 4073 22373 45077 1004021 C ATOM 7931 CA LYS C 93 15987 0159 32317 1006803 C ATOM 7847 CDlTYRC 82 47162115744839 1004250 C ATOM 7932 CB LYS C 93 15233 0116 30989 1007925 C ATOM 7848 CEl TYRC 82 5854 20793 45551 1004429 C ATOM 7933 CG LYS C 93 14928 -1288 30501 1008294 C ATOM 7849 CD2TYRC 82 460023216 46056 1004230 C ATOM 7934 CD LYS C 93 13709 -1295 29579 1008271 C ATOM 7850 CE2TYRC 82 5744 22860 46770 1004377 C ATOM 7935 CE LYSC 93 13288 -2717 29208 1008261 C ATOM 7851 CZ TYRC 82 63652165046511 1004446 C ATOM 7936 NZ LYS C 93 12068 -275728335 1008518 C 65251/C766

ATOM 7937 C LYS C 93 17487 0136 32077 1006973 C ATOM 8022 CG GLUC 105 30883-10029 16054 10020084 C ATOM 7938 O LYS C 93 18075 1158 31711 1006765 C ATOM 8023 CD GLUC 105 30458 9816 14615 10020084 C ATOM 7939 N SERC 94 18102 -1027 32298 1008412 C ATOM 8024 OEl GLU C 105 30973 -8877 13972 10020084 C ATOM 7940 CA SERC 94 19547 -1205 32121 1008657 C ATOM 8025 OE2GLUC105 29605-10587 14126 I 0020077 C ATOM 7941 CB SERC 94 20143 -I 899 33344 1009700 C ATOM 8026 C GLU C 105 30413 -6392 17286 10017547 C ATOM 7942 OG SERC 94 19540 -3168 33548 1009943 C ATOM 8027 O GLU C 105 30692 5216 17051 10017547 C ATOM 7943 C SERC 94 19830 -2041 30877 1008916 C ATOM 8028 N ALA C 106 29478 -6768 18159 10017637 C ATOM 7944 O SER C 94 19796 -3270 30929 1009043 C ATOM 8029 CA ALAC 106 28672 5836 18951 10017637 C ATOM 7945 N PRO C 95 20138 -1381 29748 1008454 C ATOM 8030 CB ALA C 106 29500 -4614 19357 1007332 C ATOM 7946 CD PROC 95 20425 0062 29641 1008899 C ATOM 8031 C ALA C 106 27413 -5392 18206 10017637 C ATOM 7947 CA PROC 95 20422 -2059 28480 1008848 C ATOM 8032 O ALAC 106 27381 -4317 17605 10017637 C ATOM 7948 CB PROC 95 20548 -090027499 1009193 C ATOM 8033 N LYSC 107 26378 -6230 18255 10014642 C ATOM 7949 CG PROC 95 21197 0151 28342 1008938 C ATOM 8034 CA LYS C 107 25100 -5945 17599 10014054 C ATOM 7950 C PRO C 95 21677 -2914 28537 1009291 C ATOM 8035 CB LYS C 107 24195 -7184 17631 10018018 C ATOM 7951 O PROC 95 21608 -4140 28624 1009634 C ATOM 8036 CG LYS C 107 24557 -8294 16651 10018013 C ATOM 7952 N CYS C 96 22827 -2257 28480 10017000 C ATOM 8037 CD LYS C 107 25906 -8924 16954 10018156 C ATOM 7953 CA CYSC 96 24094 -295628530 10016979 C ATOM 8038 CE LYS C 107 26131 -10155 16088 10017760 C ATOM 7954 C CYSC 96 24437 3312 29962 10017089 C ATOM 8039 NZ LYS C 107 25976 -9856 14638 10017786 C ATOM 7955 O CYS C 96 24779 -2446 30767 10017119 C ATOM 8040 C LYSC 107 24365 -4781 18265 10013602 C ATOM 7956 CB CYSC 96 25193 -2091 27925 10020084 C ATOM 8041 O LYSC 107 24743 -4332 19348 10013515 C ATOM 7957 SG CYS C 96 25017 -188626127 10020084 C ATOM 8042 N PROC 108 23301 -4274 17616 10010295 C ATOM 7958 N GLN C 97 24329 -4599 30270 10020084 C ATOM 8043 CD PRO C 108 22857 -4575 16242 1007478 C ATOM 7959 CA GLNC 97 24631 -5108 31599 10020084 C ATOM 8044 CA PRO C 108 22528 -3161 18174 10010169 C ATOM 7960 CB GLNC 97 23999 -6491 31774 10016199 C ATOM 8045 CB PRO C 108 21880 -2548 16939 1007393 C ATOM 7961 CG GLNC 97 22515 -6535 31440 10016199 C ATOM 8046 CG PRO C 108 21578 -3754 16115 1007131 C ATOM 7962 CD GLNC 97 22006 -7950 31212 10016199 C ATOM 8047 C PROC 108 21496 -3668 19176 10010092 C ATOM 7963 OEl GLN C 97 22104 -8808 32089 10016199 C ATOM 8048 O PROC 108 21 133 -4845 19154 1009910 C ATOM 7964 NE2 GLN C 97 21459 -819730026 10016199 C ATOM 8049 N TRP C 109 21035 -2784 20057 1008614 C ATOM 7965 C GLN C 97 26149 -5202 31751 10020084 C ATOM 8050 CA TRP C 109 20036 -3158 21051 1008359 C ATOM 7966 O GLN C 97 26669 -6199 32254 10020084 C ATOM 8051 CB TRP C 109 20654 -3261 22448 1008146 C ATOM 7967 N ARG C 98 26846 -4158 31301 10020084 C ATOM 8052 CG TRP C 109 21381 -2036 22903 10081 15 C ATOM 7968 CA ARG C 98 28306 -4087 31364 10020084 C ATOM 8053 CD2 TRP C 109 20808 -0865 23498 I 008016 C ATOM 7969 CB ARG C 98 28787 -4429 32784 10019081 C ATOM 8054 CE2TRPC109 21870 0025 23775 1007941 C ATOM 7970 CG ARGC 98 30297 -4557 32945 10019081 C ATOM 8055 CE3TRPC109 19501 -0481 23823 1008026 C ATOM 7971 CD ARGC 98 31028 -3249 32669 10019081 C ATOM 8056 CDl TRP C 109 22724 -1814 22843 1007825 C ATOM 7972 NE ARG C 98 32477 -3442 32616 10019081 C ATOM 8057 NEl TRP C 109 23028 -0579 23368 1007657 C ATOM 7973 CZ ARG C 98 33202 3971 33598 10019081 C ATOM 8058 CZ2TRPC109 21666 1275 24360 1007586 C ATOM 7974 NHl ARG C 98 34513 -410733454 10019081 C ATOM 8059 CZ3 TRP C 109 19299 0762 24406 1008002 C ATOM 7975 NH2 ARG C 98 32622 -4365 34724 10019081 C ATOM 8060 CH2 TRP C 109 20378 1 625 24668 1007566 C ATOM 7976 C ARG C 98 28981 -5002 30330 10020084 C ATOM 8061 C TRP C 109 18884 -2170 21092 1008520 C ATOM 7977 O ARG C 98 30210 5082 30269 10020084 C ATOM 8062 O TRPC 109 19068 -0967 20890 1008681 C ATOM 7978 N GLU C 99 28175 -5676 29509 10020084 C ATOM 8063 N TYRC 110 17691 -2696 21348 1006913 C ATOM 7979 CA GLUC 99 28692 -6579 28478 10020084 C ATOM 8064 CA TYRCIlO 16480 -1 888 21438 1006777 C ATOM 7980 CB GLUC 99 27605 -6900 27441 10017361 C ATOM 8065 CB TYRCIlO 15493 -2277 20347 1006655 C ATOM 7981 CG GLUC 99 26322 -609427587 10017361 C ATOM 8066 CG TYRC 110 15981 -2030 18936 1007010 C ATOM 7982 CD GLUC 99 25355 -6708 28580 10017361 C ATOM 8067 CDl TYRC 110 16965 -2832 18360 1007419 C ATOM 7983 OEl GLU C 99 25808 -7140 29662 10017361 C ATOM 8068 CEl TYRCIlO 17381 -2625 17046 1007451 C ATOM 7984 OE2 GLU C 99 24142 -6752 28280 10017361 C ATOM 8069 CD2TYRC 110 15430 -1014 18165 1007033 C ATOM 7985 C GLUC 99 29911 -6003 27759 10020084 C ATOM 8070 CE2TYRC110 15838 -0799 16858 1007570 C ATOM 7986 O GLUC 99 30934 -6673 27637 10020084 C ATOM 8071 CZ TYRC IlO 16809 -1603 16303 1007599 C ATOM 7987 N THRC 100 29790 -4762 27289 10019864 C ATOM 8072 OH TYRCIlO 17195 -1372 15002 1007719 C ATOM 7988 CA THRC 100 30865 -4070 26575 10019864 C ATOM 8073 C TYRC IlO 15832 -2109 22796 1006628 C ATOM 7989 CB THRClOO 31980 -3594 27544 10016595 C ATOM 8074 O TYRC 110 15739 -3242 23270 1006747 C ATOM 7990 OGl THR C 100 32477 -470728294 10016623 C ATOM 8075 N GLUC 111 15383 -1023 23415 1005734 C ATOM 7991 CG2THRC 100 31443 -254428507 10016712 C ATOM 8076 CA GLU ClIl 14757 -1088 24732 1005536 C ATOM 7992 C THRClOO 31492 -4937 25482 10019864 C ATOM 8077 CB GLU ClIl 15800 -0814 25806 1008070 C ATOM 7993 O THRC 100 32106 -5965 25762 10019864 C ATOM 8078 CG GLU ClIl 15661 -1696 27006 1008762 C ATOM 7994 N PROC 101 31349 -4522 24214 10019790 C ATOM 8079 CD GLU C 111 15827 -3159 26656 1009259 C ATOM 7995 CD PROClOl 30725 3262 23774 10011434 C ATOM 8080 OEl GLUClIl 16899 -3515 26127 1009280 C ATOM 7996 CA PROClOl 31896 -5253 23068 10019790 C ATOM 8081 OE2 GLUC 111 14892 -3954 26904 1009975 C ATOM 7997 CB PRO C 101 31830 -4221 21948 10011529 C ATOM 8082 C GLUClIl 13623 -0066 24846 1005594 C ATOM 7998 CG PROClOl 30583 -347622280 10011332 C ATOM 8083 O GLUClIl 13867 1 136 24925 1006130 C ATOM 7999 C PRO C 101 33311 -5778 23296 10019790 C ATOM 8084 N PROC 112 12363 -0530 24835 1005088 C ATOM 8000 O PROC 101 34266 -5006 23391 10019790 C ATOM 8085 CD PRO C 112 11917 -1879 24430 1004613 C ATOM 8001 N GLUC 102 33428 -7099 23382 10020084 C ATOM 8086 CA PRO C 112 11217 0374 24941 1005011 C ATOM 8002 CA GLU C 102 34708 -7766 23597 10020084 C ATOM 8087 CB PRO C 112 10171 0324 24084 1004220 C ATOM 8003 CB GLUC 102 34541 -9272 23355 10013392 C ATOM 8088 CG PRO C 112 10397 -1759 24441 1004333 C ATOM 8004 CG GLU C 102 35816-1009823465 10013512 C ATOM 8089 C PRO C 112 10754 0524 26390 1004714 C ATOM 8005 CD GLU C 102 36744 -9914 22278 10013643 C ATOM 8090 O PROC 112 11017 -0342 27227 1004727 C ATOM 8006 OEl GLUC 102 36316-10189 21134 10013724 C ATOM 8091 N ILEC 113 10071 1626 26682 1004389 C ATOM 8007 OE2GLUC102 37902 -9493 22490 10013555 C ATOM 8092 CA ILEC 113 9531 1856 28018 1004586 C ATOM 8008 C GLUC 102 35809 -7200 22698 10019936 C ATOM 8093 CB ILEC 113 10419 2782 28856 1006080 C ATOM 8009 O GLUC 102 36954 -7042 23127 10019642 C ATOM 8094 CG2 ILEC 113 9769 3017 30211 1005682 C ATOM 8010 N GLYC 103 35456 -6893 21454 10013943 C ATOM 8095 CGl ILEC 113 11798 2166 29052 1005786 C ATOM 8011 CA GLY C 103 36424 -6352 20516 10013675 C ATOM 8096 CDl ILE C 113 12681 2976 29994 1005834 C ATOM 8012 C GLYC 103 36101 -6759 19092 10013462 C ATOM 8097 C ILE C 113 8163 2522 27909 1005008 C ATOM 8013 O GLYC 103 36676 -6236 18137 10012911 C ATOM 8098 O ILEC 113 8020 3541 27241 1005348 C ATOM 8014 N ALAC 104 35174 7703 18953 10019810 C ATOM 8099 N TYR C 114 7162 1951 28566 1003891 C ATOM 8015 CA ALA C 104 34755 -8192 17646 10019810 C ATOM 8100 CA TYR C 114 5829 2532 28526 1003719 C ATOM 8016 CB ALA C 104 35423 -9541 17354 1009710 C ATOM 8101 CB TYR C 114 4799 1506 28051 1003806 C ATOM 8017 C ALAC 104 33232 -8335 17606 10019810 C ATOM 8102 CG TYR C 114 3431 2089 27796 1003592 C ATOM 8018 O ALAC 104 32666 -9140 18345 10019810 C ATOM 8103 CDl TYR C 114 3125 2679 26575 1004021 C ATOM 8019 N GLUC 105 32592 -7538 16747 10017547 C ATOM 8104 CEl TYR C 114 1 859 3239 26338 1003978 C ATOM 8020 CA GLU C 105 31135 -7523 16552 10017547 C ATOM 8105 CD2TYRC114 2442 2068 28789 1003609 C ATOM 8021 CB GLU C 105 30505 -8864 16953 10020084 C ATOM 8106 CE2TYRC114 1 177 2622 28567 1004042 C 65251/C766

ATOM 8107 CZ TYR C 114 0 892 3 207 27 338 1 00 40 50 C ATOM 8192 N ARG C 126 1233 21670 34141 1005642 C ATOM 8108 OH TYR C 114 -0 354 3 762 27 119 1 00 40 00 C ATOM 8193 CA ARG C 126 2151 21389 33044 1005190 C ATOM 8109 C TYR C 114 5 456 3 031 29917 1 00 37 03 C ATOM 8194 CB ARG C 126 332822368 33075 1008247 C ATOM 8110 O TYR C 114 5 813 2 420 30 920 1 0039 94 C ATOM 8195 CG ARG C 126 3001 23799 32737 1008096 C ATOM 8111 N LEU C 115 4 726 4 141 29 959 1 00 46 66 C ATOM 8196 CD ARG C 126 420724694 33025 1008588 C ATOM 8112 CA LEU C 115 4295 4 756 31 205 1 0045 70 C ATOM 8197 NE ARG C 126 40772600432384 1008943 C ATOM 8113 CB LEU C 115 5 181 5 960 31 496 1 00 56 80 C ATOM 8198 CZ ARG C 126 4311 26241 31090 1009266 C ATOM 8114 CG LEU C 115 6 191 5 936 32 645 1 00 6005 C ATOM 8199 NHl ARG C 126 4153 27466 30588 1009233 C ATOM 8115 CDl LEU C 115 6 856 4583 32 782 1 00 5843 C ATOM 8200 NH2 ARG C 126 4725 2525830293 1009085 C ATOM 8116 CD2 LEU C 115 7 215 7025 32 393 1 00 63 35 C ATOM 8201 C ARG C 126 2684 19965 33168 1005274 C ATOM 8117 C LEU C 115 2 849 5214 31 058 1 00 48 14 C ATOM 8202 O ARG C 126 3229 19593 34193 1004996 C ATOM 811 S O LEU C 115 2 470 5 744 30010 1 00 50 67 C ATOM 8203 N LEU C 127 2537 19168 32124 1004278 C ATOM 8119 N GLY C 116 2 046 5 023 32 102 1 0038 12 C ATOM 8204 CA LEU C 127 3028 17794 32162 I 003916 C ATOM 8120 CA GLY C 116 0 660 5 449 32 024 1 00 32 46 C ATOM 8205 CB LEU C 127 I 933 16829 31708 1003837 C ATOM 8121 C GLY C 116 -0 140 5278 33 296 1 003631 C ATOM 8206 CG LEU C 127 0679 1690732581 1003735 C ATOM 8122 O GLY C 116 0005 4286 34 016 1 0035 19 C ATOM 8207 CDl LEU C 127 -0468 16195 31914 1003793 C ATOM 8123 N GLY C 117 -1 000 6 253 33 563 1 0041 02 C ATOM 8208 CD2 LEU C 127 0970 16298 33923 1003801 C ATOM 8124 CA GLY C 117 -1 833 6209 34 751 1 00 44 02 C ATOM 8209 C LEU C 127 4250 17659 31263 1003891 C ATOM 8125 C GLY C 117 -2 851 7 330 34 767 1 0045 33 C ATOM 8210 O LEU C 127 4266 1818430152 1003511 C ATOM 8126 O GLY C 117 -2 776 8 239 33 948 1 0046 71 C ATOM 8211 N SER C 128 5268 16955 31757 1004240 C ATOM 8127 N VAL C 118 -3 803 7271 35 694 1 0029 05 C ATOM 8212 CA SER C 128 6507 16749 31017 I 004207 C ATOM 8128 CA VAL C 118 -4 831 8304 35 786 1 00 31 83 C ATOM 8213 CB SER C 128 7678 17398 31754 1007999 C ATOM 8129 CB VAL C 118 -6 220 7657 35 995 1 00 31 59 C ATOM 8214 OG SER C 128 7308 18647 32307 1008584 C ATOM 8130 CGl VAL C 118 -7291 8 727 36 165 1 0032 99 C ATOM 8215 C SER C 128 6806 15260 30860 1004125 C ATOM 8131 CG2 VAL C 118 -6 539 6 771 34 806 1 00 31 65 C ATOM 8216 O SER C 128 6596 14468 31779 1004253 C ATOM 8132 C VAL C 118 -4 512 9 277 36 921 1 0029 74 C ATOM 8217 N ALA C 129 7295 14889 29688 1004988 C ATOM 8133 O VAL C 118 -4 100 8 852 38 000 1 0033 69 C ATOM 8218 CA ALA C 129 7662 1351429414 1005085 C ATOM 8134 N PHE C 119 -4 706 10 573 36 670 1 0032 16 C ATOM 8219 CB ALA C 129 6806 12960 28289 1006491 C ATOM 8135 CA PHE C 119 -4 395 11 606 37 660 1 00 33 47 C ATOM 8220 C ALA C 129 9129 13594 28995 1004962 C ATOM 8136 CB PHE C 119 -2 988 12 173 37 408 1 0027 78 C ATOM 8221 O ALA C 129 9434 1389427845 1005050 C ATOM 8137 CG PHE C 119 -1 885 11 152 37 536 1 00 25 38 C ATOM 8222 N GLU C 130 10033 13328 29930 1005271 C ATOM 8138 CDl PHE C 119 -1 554 10 326 36469 1 0023 57 C ATOM 8223 CA GLU C 130 II 454 13423 29657 1005368 C ATOM 8139 CD2 PHE C 119 -1 213 10 970 38 747 1 0024 06 C ATOM 8224 CB GLU C 130 12051 14481 30582 1009740 C ATOM 8140 CEl PHEC 119 -0 570 9328 36 603 1 002464 C ATOM 8225 CG GLU C 130 11411 15845 30404 1009694 C ATOM 8141 CE2 PHE C 119 -0 240 9 985 38 886 1 00 24 87 C ATOM 8226 CD GLU C 130 11604 16763 31600 10010243 C ATOM 8142 CZ PHE C 119 0 083 9 159 37 806 1 0023 96 C ATOM 8227 OEl GLU C 130 11171 17936 31523 10010380 C ATOM 8143 C PHE C 119 -5 378 12 780 37 727 1 0034 38 C ATOM 8228 OE2 GLU C 130 12179 16318 32618 10010224 C ATOM 8144 O PHE C 1 19 -6 014 13 137 36 727 1 0030 48 C ATOM 8229 C GLU C 130 12237 12121 29780 1005007 C ATOM 8145 N GLN C 120 -5 488 13 370 38 922 1 00 38 70 C ATOM 8230 O GLU C 130 11764 11152 30364 1004999 C ATOM 8146 CA GLN C 120 -6 344 14525 39 171 1 0042 07 C ATOM 8231 N ILE C 131 13433 12108 29194 1003629 C ATOM 8147 CB GLN C 120 6 725 14594 40 647 1 00 69 48 C ATOM 8232 CA ILE C 131 14346 10969 29250 1003883 C ATOM 8148 CG GLN C 120 -8 211 14 588 40 943 1 00 69 63 C ATOM 8233 CB ILE C 131 14458 1024927901 1005450 C ATOM 8149 CD GLN C 120 -8 971 15 649 40 180 1 00 69 23 C ATOM 8234 CG2 ILE C 131 13131 959627554 1005473 C ATOM 8150 OEl GLN C 120 -8 506 16 773 40 040 1 0068 79 C ATOM 8235 CGl ILE C 131 14903 11239 26826 1005069 C ATOM 8151 NE2 GLN C 120 -10 155 15 300 39 694 1 00 72 06 C ATOM 8236 CDl ILE C 131 15129 10600 25478 1004930 C ATOM 8152 C GLN C 120 -5 459 15 723 38 830 1 0041 21 C ATOM 8237 C ILE C 131 15726 11516 29616 1004072 C ATOM 8153 O GLN C 120 -4 389 15 883 39416 1 0043 91 C ATOM 8238 O ILE C 131 15980 12711 29470 1004144 C ATOM 8154 N LEU C 121 5 900 16 562 37 894 1 0032 45 C ATOM 8239 N ASN C 132 16618 1064730076 1006223 C ATOM 8155 CA LEU C 121 -5 123 17 727 37 465 1 00 34 11 C ATOM 8240 CA ASN C 132 17952 11075 30473 1005923 C ATOM 8156 CB LEU C 121 -4 678 17545 36 009 1 00 30 55 C ATOM 8241 CB ASN C 132 18393 1028631693 1005693 C ATOM 8157 CG LEU C 121 3 322 16900 35 711 1 0028 82 C ATOM 8242 CG ASN C 132 18574 8824 31386 1005563 C ATOM 8158 CDl LEU C 121 -2 912 15 933 36781 1 00 3021 C ATOM 8243 ODl ASN C 132 17779 8228 30661 1005732 C ATOM 8159 CD2 LEU C 121 -3 405 16218 34363 1 002431 C ATOM 8244 ND2ASN C 132 19620 822731939 1005346 C ATOM 8160 C LEU C 121 -5 902 19 016 37 582 1 0036 15 C ATOM 8245 C ASN C 132 19003 10932 29372 1005688 C ATOM 8161 O LEU C 121 -7 125 19 022 37444 1 0041 42 C ATOM 8246 O ASN C 132 19976 11676 29365 1006005 C ATOM 8162 N GLU C 122 -5 175 20 106 37 826 1 004438 C ATOM 8247 N ARG C 133 18816 9985 28451 1007042 C ATOM 8163 CA GLU C 122 -5 748 21 451 37 959 1 0045 92 C ATOM 8248 CA ARG C 133 19775 9768 27357 1006601 C ATOM 8164 CB GLU C 122 -4976 22297 38 982 1 00113 28 C ATOM 8249 CB ARG C 133 20372 8360 27447 1008713 C ATOM 8165 CG GLU C 122 -4902 21 809 40410 1 0011632 C ATOM 8250 CG ARG C 133 21136 8088 28727 1008971 C ATOM 8166 CD GLU C 122 -4 003 22 710 41 259 1 00121 60 C ATOM 8251 CD ARG C 133 22265 9083 28913 1009495 C ATOM 8167 OEl GLU C 122 -2 790 22 803 40957 1 00123 10 C ATOM 8252 NE ARG C 133 23223 905027810 1009281 C ATOM 8168 OE2 GLU C 122 -4 508 23 334 42 219 1 00121 69 C ATOM 8253 CZ ARG C 133 24089 8065 27592 1009391 C ATOM 8169 C GLU C 122 -5 623 22 185 36 623 I 0044 72 C ATOM 8254 NHl ARG C 133 24920 812826559 1009659 C ATOM 8170 O GLU C 122 -4 712 21 918 35 844 1 0045 91 C ATOM 8255 NH2 ARG C 133 24131 701928410 1009320 C ATOM 8171 N LYS C 123 -6 525 23 125 36368 1 0046 18 C ATOM 8256 C ARG C 133 19181 9971 25959 1007060 C ATOM 8172 CA LYS C 123 -6434 23 922 35 156 1 00 4703 C ATOM 8257 O ARG C 133 19049 902425187 1007296 C ATOM 8173 CB LYS C 123 -7 579 24 927 35 091 1 00 73 83 C ATOM 8258 N PRO C 134 18836 11219 25611 1005827 C ATOM 8174 CG LYS C 123 -7419 25 923 33 975 1 00 6999 C ATOM 8259 CD PRO C 134 19069 12455 26372 1005601 C ATOM 8175 CD LYS C 123 -8 509 26 959 34 007 1 00 67 66 C ATOM 8260 CA PRO C 134 18259 11530 24300 1006199 C ATOM 8176 CE LYS C 123 -8 291 27 991 32 912 1 00 69 39 C ATOM 8261 CB PRO C 134 18031 13039 24368 1005873 C ATOM 8177 NZ LYS C 123 -9 309 29 089 32 969 1 00 73 40 C ATOM 8262 CG PRO C 134 19114 13487 25269 1006073 C ATOM 8178 C LYS C 123 -5 096 24 676 35 237 1 00 47 85 C ATOM 8263 C PRO C 134 19154 1114023141 1006717 C ATOM 8179 O LYS C 123 -4 811 25 359 36228 1 00 52 61 C ATOM 8264 O PRO C 134 18723 11146 21993 1007021 C ATOM 8180 N GLY C 124 -4269 24 539 34207 1 0038 64 C ATOM 8265 N ASP C 135 20401 1080623439 1007152 C ATOM 8181 CA GLY C 124 -2 986 25214 34 209 1 00 39 75 C ATOM 8266 CA ASP C 135 21322 10406 22392 1006798 C ATOM 8182 C GLY C 124 -1 784 24 322 34473 1 0041 16 C ATOM 8267 CB ASP C 135 22766 10559 22875 1009125 C ATOM 8183 O GLY C 124 -0 652 24 765 34284 1 0041 96 C ATOM 8268 CG ASP C 135 22963 1007024290 1009072 C ATOM 8184 N ASP C 125 -2004 23 083 34912 1 0041 18 C ATOM 8269 ODl ASP C 135 22999 8845 24495 1008666 C ATOM 8185 CA ASP C 125 -0 888 22 178 35 189 1 003997 C ATOM 8270 OD2ASPC135 23074 10912 25205 1009230 C ATOM 8186 CB ASP C 125 -1 386 20 858 35 778 1 00 68 88 C ATOM 8271 C ASP C 135 21045 8975 21929 1006669 C ATOM 8187 CG ASP C 125 -1 909 21 004 37 199 1 00 7434 C ATOM 8272 O ASPC 135 21547 8545 20894 1007338 C ATOM 8188 ODl ASP C 125 -1 701 22070 37 820 1 00 75 99 C ATOM 8273 N TYRC 136 20229 8245 22684 1006090 C ATOM 8189 OD2 ASP C 125 2 522 20037 37 697 1 00 73 00 C ATOM 8274 CA TYRC 136 19883 6869 22333 1006211 C ATOM 8190 C ASP C 125 -0062 21 894 33 941 1 003902 C ATOM 8275 CB TYR C 136 19997 5965 23555 1007849 C ATOM 8191 O ASP C 125 -0 577 21 893 32 821 1 00 35 93 C ATOM 8276 CG TYR C 136 21402 561023967 1007810 C 65251/C766

ATOM 8277 CDl TYR C 136 21878 593725236 1007770 C ATOM 8362 C TYRC 146 4510 9771 23318 1003811 C ATOM 8278 CEl TYR C 136 23155 5565 25646 1008025 C ATOM 8363 O TYR C 146 5047 9192 24267 1003628 C ATOM 8279 CD2 TYR C 136 22239 4902 23112 1008027 C ATOM 8364 N PHE C 147 3634 10752 23468 1003361 C ATOM 8280 CE2 TYR C 136 23518 4522 23513 1007974 C ATOM 8365 CA PHE C 147 3251 11277 24762 1003313 C ATOM 8281 CZ TYR C 136 23967 485824782 1008104 C ATOM 8366 CB PHEC 147 4270 12355 25140 1003134 C ATOM 8282 OH TYR C 136 25222 4480 25192 1008488 C ATOM 8367 CG PHEC 147 3903 13183 26330 1003039 C ATOM 8283 C TYR C 136 18454 6788 21801 1006402 C ATOM 8368 CDl PHEC 147 3261 12627 27423 1003088 C ATOM 8284 O TYR C 136 17940 5702 21528 1006690 C ATOM 8369 CD2PHEC 147 4292 14528 26391 1003272 C ATOM 8285 N LEU C 137 17815 7941 21654 1007175 C ATOM 8370 CEl PHE C 147 3017 1339428567 1003121 C ATOM 8286 CA LEU C 137 16442 7997 21184 1006846 C ATOM 8371 CE2 PHE C 147 4051 15302 27530 1003129 C ATOM 8287 CB LEU C 137 15933 9430 21250 1006739 C ATOM 8372 CZ PHE C 147 3414 14729 28621 1003213 C ATOM 8288 CG LEU C 137 14730 9696 22144 1006512 C ATOM 8373 C PHE C 147 1857 11855 24572 1003467 C ATOM 8289 CDl LEU C 137 14239 11106 21872 1006726 C ATOM 8374 O PHE C 147 1614 1261423643 1003215 C ATOM 8290 CD2 LEU C 137 13626 8689 21866 1006888 C ATOM 8375 N GLY C 148 0924 11467 25423 1003363 C ATOM 8291 C LEU C 137 16246 7494 19767 1006783 C ATOM 8376 CA GLY C 148 -0420 1199025284 1003811 C ATOM 8292 O LEU C 137 16780 8086 18830 1006668 C ATOM 8377 C GLY C 148 -1238 11976 26564 1004033 C ATOM 8293 N LEU C 138 15483 6410 19603 1006112 C ATOM 8378 O GLY C 148 -0846 11398 27576 1004294 C ATOM 8294 CA LEU C 138 15192 5897 18262 1005892 C ATOM 8379 N ILE C 149 -2384 12643 26506 1003568 C ATOM 8295 CB LEU C 138 15253 4366 18192 1006788 C ATOM 8380 CA ILE C 149 -3305 12705 27620 1003409 C ATOM 8296 CG LEU C 138 14679 3829 16861 1006400 C ATOM 8381 CB ILE C 149 2983 13869 28571 1004366 C ATOM 8297 CDl LEU C 138 15275 4597 15688 1006557 C ATOM 8382 CG2 ILE C 149 -1511 13839 28952 1004421 C ATOM 8298 CD2 LEU C 138 14952 2346 16712 1006692 C ATOM 8383 CGl ILE C 149 -3305 15202 27903 1003970 C ATOM 8299 C LEU C 138 13811 6346 17800 1006227 C ATOM 8384 CDl ILE C 149 -3165 16363 28849 1004295 C ATOM 8300 O LEU C 138 12799 5740 18145 1006142 C ATOM 8385 C ILE C 149 -4720 1288027084 1003613 C ATOM 8301 N PHE C 139 13778 7419 17024 1006425 C ATOM 8386 O ILE C 149 -4939 13483 26036 1004130 C ATOM 8302 CA PHE C 139 12527 7929 16497 1006563 C ATOM 8387 N ILE C 150 -5678 1233827812 1004887 C ATOM 8303 CB PHE C 139 12287 9366 16988 1009297 C ATOM 8388 CA ILE C 150 -7074 1242727433 1004938 C ATOM 8304 CG PHE C 139 13493 10261 16899 1009212 C ATOM 8389 CB ILE C 150 -7538 11104 26752 1003700 C ATOM 8305 CDl PHE C 139 13638 11324 17782 1009165 C ATOM 8390 CG2 ILE C 150 -7234 9915 27644 1004030 C ATOM 8306 CD2 PHE C 139 14470 10062 15930 1009473 C ATOM 8391 CGl ILE C 150 -9032 11 155 26442 1003499 C ATOM 8307 CEl PHE C 139 14738 12174 17703 1009629 C ATOM 8392 CDl ILE C 150 -9395 1209625336 1003300 C ATOM 8308 CE2 PHEC 139 15572 10907 15843 1009227 C ATOM 8393 C ILE C 150 -7859 1267028723 1005072 C ATOM 8309 CZ PHE C 139 15705 11965 16732 1009621 C ATOM 8394 O ILE C 150 -7601 12035 29746 1004983 C ATOM 8310 C PHE C 139 12583 7857 14973 1006966 C ATOM 8395 N ALA C 151 -8794 1360928687 1004642 C ATOM 8311 O PHE C 139 12102 8748 14269 1006976 C ATOM 8396 CA ALA C 151 -9598 1390029861 I 004516 C ATOM 8312 N ALA C 140 13177 6774 14476 1006880 C ATOM 8397 CB ALA C 151 -10171 15289 29753 1002347 C ATOM 8313 CA ALA C 140 13326 6564 13041 1007010 C ATOM 8398 C ALA C 151 -10724 12864 30007 1004612 C ATOM 8314 CB ALA C 140 14445 5574 12779 1007335 C ATOM 8399 O ALA C 151 -11526 1265629097 1004850 C ATOM 8315 C ALA C 140 12051 6075 12371 1007049 C ATOM 8400 N LEU C 152 10769 12205 31157 1007318 C ATOM 8316 O ALA C 140 11670 6584 11314 1007238 C ATOM 8401 CA LEU C 152 -11786 11201 31402 1007716 C ATOM 8317 N GLU C 141 11398 5088 12984 1008620 C ATOM 8402 CB LEU C 152 -11150 9965 32021 1005401 C ATOM 8318 CA GLU C 141 10177 4528 12421 1008938 C ATOM 8403 CG LEU C 152 10100 9296 31 146 1005526 C ATOM 8319 CB GLU C 141 9812 3210 13117 10020084 C ATOM 8404 CDl LEU C 152 -9494 8118 31885 1005295 C ATOM 8320 CG GLU C 141 8628 2470 12483 10020084 C ATOM 8405 CD2 LEU C 152 -10736 8840 29856 1005446 C ATOM 8321 CD GLU C 141 7272 2959 12978 10020084 C ATOM 8406 C LEU C 152 -12870 11739 32319 1008001 C ATOM 8322 OEl GLU C 141 6277 2812 12238 10020084 C ATOM 8407 O LEU C 152 -13998 11963 31886 1008587 C ATOM 8323 OE2 GLU C 141 7194 3476 14113 10020084 C ATOM 8408 N ILE C 153 836423567 5314 1004798 C ATOM 8324 C GLU C 141 8979 5474 12444 1009148 C ATOM 8409 CA ILE C 153 853722788 4095 1004798 C ATOM 8325 O GLU C 141 8701 6134 11447 1009516 C ATOM 8410 CB ILE C 153 9039 21361 4396 1005212 C ATOM 8326 N SER C 142 8272 5559 13564 10013057 C ATOM 841 1 CG2 ILE C 153 1048021411 4853 1004890 C ATOM 8327 CA SER C 142 7095 6415 13594 10013356 C ATOM 8412 CGl ILE C 153 8159 20711 5462 1004890 C ATOM 8328 CB SER C 142 6133 5968 12491 1004670 C ATOM 8413 CDl ILE C 153 8588 19309 5810 1004890 C ATOM 8329 OG SER C 142 5149 6948 12234 1004758 C ATOM 8414 C ILE C 153 724422701 3307 1004798 C ATOM 8330 C SER C 142 6360 6421 14934 10013488 C ATOM 8415 O ILE C 153 6152 22907 3842 1004798 C ATOM 8331 O SER C 142 6499 7361 15725 10013997 C ATOM 8416 N THR C 154 7382 22369 2030 1005740 C ATOM 8332 N GLY C 143 5558 5387 15181 1004699 C ATOM 8417 CA THR C 154 624822290 1127 1005740 C ATOM 8333 CA GLY C 143 4835 5338 16440 1004446 C ATOM 8418 CB THR C 154 6100 23630 0398 1005074 C ATOM 8334 C GLY C 143 5677 4737 17557 1004253 C ATOM 8419 OGl THR C 154 502424360 0991 1006102 C ATOM 8335 O GLY C 143 5152 4002 18394 1004452 C ATOM 8420 CG2 THR C 154 5865 23433 -1111 1006102 C ATOM 8336 N GLN C 144 6973 5056 17573 1005015 C ATOM 8421 C THRC 154 6331 21176 0088 1005740 C ATOM 8337 CA GLN C 144 7904 4525 18565 1004468 C ATOM 8422 O THR C 154 741020853 0407 1005740 C ATOM 8338 CB GLN C 144 9265 4254 17921 1006835 C ATOM 8423 N LEU C 155 518020586 -0227 1006314 C ATOM 8339 CG GLN C 144 9195 3502 16611 1006763 C ATOM 8424 CA LEU C 155 5105 19549 -1250 1006314 C ATOM 8340 CD GLN C 144 10566 3131 16072 1006760 C ATOM 8425 CB LEU C 155 4898 18161 -0642 1006137 C ATOM 8341 OEl GLN C 144 11464 3971 15983 1007317 C ATOM 8426 CG LEU C 155 4910 17027 -1681 1005795 C ATOM 8342 NE2 GLN C 144 10729 1867 15696 1006614 C ATOM 8427 CDl LEU C 155 6190 17077 -2503 1005795 C ATOM 8343 C GLN C 144 8108 5442 19760 1004648 C ATOM 8428 CD2 LEU C 155 4799 15691 0990 1005795 C ATOM 8344 O GLN C 144 8538 4999 20826 1004879 C ATOM 8429 C LEU C 155 3920 19918 -2134 1006314 C ATOM 8345 N VAL C 145 7813 6720 19582 1005023 C ATOM 8430 O LEU C 155 2782 19964 -1662 1006314 C ATOM 8346 CA VAL C 145 7980 767920661 1004848 C ATOM 8431 N LYS C 156 419020204 -3409 1006644 C ATOM 8347 CB VAL C 145 9281 8499 20469 1004236 C ATOM 8432 CA LYS C 156 313620593 -4337 1006644 C ATOM 8348 CGl VAL C 145 9468 9482 21614 1004052 C ATOM 8433 CB LYS C 156 328722068 -4710 1007082 C ATOM 8349 CG2 VAL C 145 10465 756820384 1003944 C ATOM 8434 CG LYS C 156 2143 22586 -5565 1007301 C ATOM 8350 C VALC 145 6775 861920677 1004959 C ATOM 8435 CD LYS C 156 228224067 -5933 1007301 C ATOM 8351 O VAL C 145 6551 9380 19736 1005227 C ATOM 8436 CE LYS C 156 343024318 -6910 1007301 C ATOM 8352 N TYR C 146 5985 854921742 1004159 C ATOM 8437 NZ LYS C 156 3472 25732 -7383 1007301 C ATOM 8353 CA TYR C 146 4810 9401 21864 1003980 C ATOM 8438 C LYS C 156 3090 19761 5612 1006644 C ATOM 8354 CB TYR C 146 3588 873421221 1004697 C ATOM 8439 O LYS C 156 4121 19535 -6249 1006644 C ATOM 8355 CG TYR C 146 3370 7299 21655 1004700 C ATOM 8440 N TYR C 157 1885 19307 -5968 1005342 C ATOM 8356 CDl TYR C 146 4016 6245 21003 1004639 C ATOM 8441 CA TYR C 157 1642 18526 -7181 1005342 C ATOM 8357 CEl TYRC 146 3848 4931 21426 1004518 C ATOM 8442 CB TYR C 157 0922 17219 -6848 1006652 C ATOM 8358 CD2 TYR C 146 2544 6993 22746 1004259 C ATOM 8443 CG TYR C 157 1801 16149 -6234 1004886 C ATOM 8359 CE2 TYR C 146 2373 567923174 1004464 C ATOM 8444 CDl TYR C 157 3123 16418 -5882 1004886 C ATOM 8360 CZ TYR C 146 3024 465722514 1004468 C ATOM 8445 CEl TYR C 157 3930 15435 -5308 1004886 C ATOM 8361 OH TYRC 146 2855 336722956 1004566 C ATOM 8446 CD2 TYR C 157 1305 14866 -5999 1004886 C 65251/C766

ATOM 8447 CE2TYRC157 2105 13874 -5426 1004886 C ATOM 8532 CB LEUC 168 3269 17538 29482 10010796 C ATOM 8448 CZ TYRC 157 3416 14164 -5082 1004886 C ATOM 8533 CG LEUC 168 -2880 17331 -30950 10010796 C ATOM 8449 OH TYRC 157 4219 13202 -4509 1004886 C ATOM 8534 CDl LEU C 168 -1534 16636-31039 10010796 C ATOM 5450 C TYRC 157 0765 19377 -8105 1005342 C ATOM 8535 CD2LEUC 168 -3958 16525-31658 10010796 C ATOM 5451 O TYRC 157 -0287 19883 -7682 1005342 C ATOM 8536 C LEUC 168 -4512 19070-27951 10013470 C ATOM 8452 N ASNC 158 1205 19537 -9356 1006575 C ATOM 8537 O LEU C 168 -4453 20296-27852 10013470 C ATOM 8453 CA ASNC 158 0485 20347-10345 1006575 C ATOM 8538 N TYRC 169 -4570 18256 -26903 1009330 C ATOM 8454 CB ASNC 158 129421627-10648 1005721 C ATOM 8539 CA TYRC 169 -4534 18746-25540 1009330 C ATOM 8455 CG ASNC 158 058622581 -11611 1006791 C ATOM 8540 CB TYRC 169 -5663 18131 -24716 1007075 C ATOM 8456 ODl ASN C 158 -0495 22279 12123 1006791 C ATOM 8541 CG TYRC 169 -7044 18601 -25083 1007075 C ATOM 8457 ND2ASNC158 1215 23737-11852 1006791 C ATOM 8542 CDl TYRC 169 -7687 18122-26215 1007075 C ATOM 8458 C ASN C 158 0254 19558-11635 1006575 C ATOM 8543 CElTYRC 169 -8968 18553 -26547 1007075 C ATOM 8459 O ASN C 158 1203 19198-12332 1006575 C ATOM 8544 CD2TYRC 169 -7712 19526-24286 1007075 C ATOM 8460 N TYR C 159 -1009 19271-11932 1005368 C ATOM 8545 CE2TYRC 169 -8989 19966 -24603 1007075 C ATOM 8461 CA TYRC 159 -1358 18558-13152 1005368 C ATOM 8546 CZ TYRC 169 -9613 19477 25733 1007075 C ATOM 8462 CB TYRC 159 -2337 17412-12894 1006495 C ATOM 8547 OH TYRC 169 -10878 19920-26045 1007075 C ATOM 8463 CG TYRC 159 -1844 16285-12024 1006851 C ATOM 8548 C TYR C 169 -3206 18318-24945 1009330 C ATOM 8464 CDl TYRC 159 -1901 16378-10634 1006851 C ATOM 8549 O TYR C 169 -2897 17126-24908 1009330 C ATOM 8465 CElTYRC 159 -1528 15311 -9826 1006851 C ATOM 8550 N ASPC 170 -2411 19281 -24494 1007682 C ATOM 8466 CD2TYRC159 -1392 15094-12589 1006851 C ATOM 8551 CA ASP C 170 1132 18943-23881 1007682 C ATOM 8467 CE2TYRC 159 -1015 14019-11790 1006851 C ATOM 8552 CB ASP C 170 -0111 20064-24066 10010720 C ATOM 8468 CZ TYRC 159 -1088 14133-10405 1006851 C ATOM 8553 CG ASP C 170 0734 19876-25305 10010720 C ATOM 8469 OH TYRC 159 -0732 13070 -9603 1006851 C ATOM 8554 ODlASPC 170 1098 18716-25598 10010720 C ATOM 8470 C TYRC 159 -2057 19576-14041 1005368 C ATOM 8555 OD2ASPC 170 104720881 -25975 10010720 C ATOM 8471 O TYRC 159 -2995 20263-13597 1005368 C ATOM 8556 C ASPC 170 1316 18674-22399 1007682 C ATOM 8472 N THR C 160 -1618 19677-15293 1008004 C ATOM 8557 O ASPC 170 -2261 19164-21780 1007682 C ATOM 8473 CA THRC 160 -2227 20638-16204 1008004 C ATOM 8558 N GLY C 171 -0412 17883-21838 1006500 C ATOM 8474 CB THRC 160 -1422 21948-16219 1009591 C ATOM 8559 CA GLYC 171 -0500 17571 -20432 1006500 C ATOM 8475 OGlTHRC 160 -1256 22425-14877 1008325 C ATOM 8560 C GLYC 171 0862 17578-19774 1006500 C ATOM 8476 CG2THRC160 -2149 23001 -17036 1008325 C ATOM 8561 O GLY C 171 1837 17047-20318 1006500 C ATOM 8477 C THR C 160 -2392 20178-17649 1008004 C ATOM 8562 N VALC 172 0938 18208-18607 1007307 C ATOM 8478 O THR C 160 1431 19727-18278 1008004 C ATOM 8563 CA VALC 172 2178 18246-17844 1007307 C ATOM 8479 N VALC 161 -3619 20275-18162 1007722 C ATOM 8564 CB VALC 172 2927 19586-17946 1007173 C ATOM 8480 CA VALC 161 -3882 19934-19558 1007722 C ATOM 8565 CGl VALC 172 3813 19581 -19151 1006374 C ATOM 8481 CB VALC 161 5011 18884-19744 10010100 C ATOM 8566 CG2VALC 172 193720745 -17979 1006374 C ATOM 8482 CGl VALC 161 -4752 17689-18863 1008551 C ATOM 8567 C VALC 172 1883 18041 16383 1007307 C ATOM 8483 CG2VALC 161 -6362 19493-19457 1008551 C ATOM 8568 O VALC 172 0773 18286-15909 1007307 C ATOM 8484 C VALC 161 -429421241 -20223 1007722 C ATOM 8569 N PHEC 173 2905 17593-15674 1006865 C ATOM 8485 O VALC 161 -5084 22015-19662 1007722 C ATOM 8570 CA PHEC 173 2806 17373-14259 1006865 C ATOM 8486 N THR C 162 -374421493 -21407 10012439 C ATOM 8571 CB PHE C 173 2595 15902-13956 1007977 C ATOM 8487 CA THRC 162 -4023 22726-22136 10012439 C ATOM 8572 CG PHEC 173 2797 15577-12517 1006159 C ATOM 8488 CB THRC 162 -275623588-22246 10010903 C ATOM 8573 CDl PHEC 173 1827 15916 11581 1006159 C ATOM 8489 OGl THR C 162 -196023408 -21070 1008036 C ATOM 8574 CD2PHEC173 3996 15016-12082 1006159 C ATOM 8490 CG2THRC 162 -3118 25059 -22382 1008036 C ATOM 8575 CEl PHE C 173 2047 15706-10238 1006159 C ATOM 8491 C THRC 162 -4515 22445-23546 10012439 C ATOM 8576 CE2PHEC173 4229 14801-10740 1006159 C ATOM 8492 O THRC 162 -4138 21443-24154 10012439 C ATOM 8577 CZ PHE C 173 3253 15147 -9812 1006159 C ATOM 8493 N LEUC 163 -535423332-24069 10010984 C ATOM 8578 C PHEC 173 4107 17814-13609 1006865 C ATOM 8494 CA LEUC 163 -5859 23160-25418 10010984 C ATOM 8579 O PHEC 173 5190 17509-14110 1006865 C ATOM 8495 CB LEUC 163 -713823967 -25630 10013126 C ATOM 8580 N TYRC 174 4004 18530-12496 1006496 C ATOM 8496 CG LEU C 163 8321 23124-26117 1007935 C ATOM 8581 CA TYRC 174 5191 18967-11778 1006496 C ATOM 8497 CDl LEUC 163 -947624029-26496 1007935 C ATOM 8582 CB TYRC 174 5368 20483 -11864 1009843 C ATOM 8498 CD2LEUC 163 -7898 22269-27311 1007935 C ATOM 8583 CG TYR C 174 5673 20999-13245 1008447 C ATOM 8499 C LEUC 163 -480023615 -26408 10010984 C ATOM 8584 CDl TYR C 174 469621658 -13993 1008447 C ATOM 8500 O LEU C 163 -494623423 27614 10010984 C ATOM 8585 CEl TYRC 174 497422156-15267 1008447 C ATOM 8501 N LYSC 164 -372624208 -25892 10020027 C ATOM 8586 CD2TYRC 174 694020844-13805 1008447 C ATOM 8502 CA LYS C 164 -264424697 -26742 10020027 C ATOM 8587 CE2 TYRC 174 722821336-15081 1008447 C ATOM 8503 CB LYS C 164 -181723529-27284 10011213 C ATOM 8588 CZ TYR C 174 6241 21992-15805 1008447 C ATOM 8504 CG LYS C 164 -0488 23330-26576 10011188 C ATOM 8589 OH TYRC 174 652022493-17059 1008447 C ATOM 8505 CD LYS C 164 040824546-26754 10011188 C ATOM 8590 C TYRC 174 5099 18576-10313 1006496 C ATOM 8506 CE LYS C 164 175724362 -26074 10011188 C ATOM 8591 O TYRC 174 4046 18717 -9689 1006496 C ATOM 8507 NZ LYS C 164 2678 25504-26357 10011188 C ATOM 8592 N ASP C 175 6213 18082 9783 1006260 C ATOM 8508 C LYS C 164 -325425469 -27898 10020027 C ATOM 8593 CA ASP C 175 6326 17684 -8390 1006260 C ATOM 8509 O LYSC 164 -4403 25904-27812 10020027 C ATOM 8594 CB ASP C 175 6826 16239 -8290 10011092 C ATOM 8510 N ASPC 165 -249225650-28972 10019757 C ATOM 8595 CG ASP C 175 6850 15722 -6861 1009913 C ATOM 8511 CA ASP C 165 -3013 26356-30135 10019757 C ATOM 8596 ODl ASP C 175 7082 16523 -5936 1009913 C ATOM 8512 CB ASP C 165 -192226521 -31202 10012933 C ATOM 8597 OD2 ASP C 175 6651 14509 -6659 1009913 C ATOM 8513 CG ASPC 165 -1188 25223-31504 10012933 C ATOM 8598 C ASPC 175 7368 18630 -7794 1006260 C ATOM 8514 ODlASPC 165 -1823 24274-32016 10012933 C ATOM 8599 O ASP C 175 8548 18569 -8162 1006260 C ATOM 8515 OD2ASPC165 003025152 -31229 10012933 C ATOM 8600 N HIS C 176 6938 19504 -6886 1006045 C ATOM 8516 C ASP C 165 -418025533 -30670 10019757 C ATOM 8601 CA HISC 176 7853 20452 -6253 1006045 C ATOM 8517 O ASP C 165 -503425088 -29902 10019757 C ATOM 8602 CB HISC 176 740621881 -6539 10010128 C ATOM 8518 N ASP C 166 -423025314 -31975 1008628 C ATOM 8603 CG HIS C 176 7693 22343 -7930 1007041 C ATOM 8519 CA ASP C 166 -5325 24530-32513 1008628 C ATOM 8604 CD2HISC 176 6865 22599 -8969 1007041 C ATOM 8520 CB ASP C 166 -5755 25096 -33859 10020084 C ATOM 8605 NDl HIS C 176 896922627 -8371 1007041 C ATOM 8521 CG ASPC 166 -6345 26483 -33730 10020084 C ATOM 8606 CEl HISC 176 8913 23043 -9622 1007041 C ATOM 8522 ODl ASP C 166 -562727392 -33262 10020084 C ATOM 8607 NE2HISC 176 764823035-10009 1007041 C ATOM 8523 OD2ASPC166 -752726663 -34085 10020084 C ATOM 8608 C HISC 176 796420292 -4743 1006045 C ATOM 8524 C ASP C 166 -500423046 -32632 1008628 C ATOM 8609 O HIS C 176 695520285 -4039 1006045 C ATOM 8525 O ASP C 166 -405622651-33319 1008628 C ATOM 8610 N TYR C 177 919020149 -4253 1006578 C ATOM 8526 N GLYC 167 -5788 22229-31928 1009604 C ATOM 8611 CA TYR C 177 943720065 -2818 1006578 C ATOM 8527 CA GLYC 167 559020797 -31996 1009604 C ATOM 8612 CB TYR C 177 10463 18990 -2484 1006517 C ATOM 8528 C GLYC 167 -5730 19956 -30745 1009604 C ATOM 8613 CG TYR C 177 10787 18977 -1020 1005818 C ATOM 8529 O GLYC 167 -6779 19899-30098 1009604 C ATOM 8614 CDl TYRC 177 9826 18601 -0081 1005818 C ATOM 8530 N LEUC 168 -4630 19287-30431 10013470 C ATOM 8615 CEl TYR C 177 10097 18645 1286 1005818 C ATOM 8531 CA LEU C 168 -4533 18379-29308 10013470 C ATOM 8616 CD2TYRC177 12031 19392 -0561 1005818 C 65251/C766

ATOM 8617 CE2TYRC177 12314 19440 0800 1005818 C ATOM 8702 C TYR C 187 2573 13491-23711 1007124 C ATOM 8618 CZ TYRC 177 11341 19066 1718 10058 IS C ATOM 8703 O TYR C 187 2670 14465-24455 1007124 C ATOM 8619 OH TYRC 177 11608 19132 3068 1005818 C ATOM 8704 N ASN C 188 2995 12278-24047 10011491 C ATOM 8620 C TYR C 177 10033 21434 -2533 1006578 C ATOM 8705 CA ASN C 188 3610 11994 25334 10011491 C ATOM 8621 O TYR C 177 11 127 21727 -2999 1006578 C ATOM 8706 CB ASNC 188 4529 10787-25193 10020084 C ATOM 8622 N ASN C 178 9337 22266 -1763 1006747 C ATOM 8707 CG ASN C 188 5243 10458-26471 1008271 C ATOM 8623 CA ASNC 178 9810 23627 -1521 1006747 C ATOM 8708 ODl ASN C 188 4620 10300-27518 1008271 C ATOM 8624 CB ASNC 178 11210 23647 -0911 1007072 C ATOM 8709 ND2ASNC188 6559 10347 -26398 1008271 C ATOM 8625 CG ASNC 178 11210 23282 0540 10063 19 C ATOM 8710 C ASN C 188 2512 11694-26358 10011491 C ATOM 8626 ODl ASN C 178 10155 23212 1 170 1006319 C ATOM 8711 O ASN C 188 1832 10672-26263 10011491 C ATOM 8627 ND2ASNC178 12400 23057 1097 1006319 C ATOM 8712 N HIS C 189 2342 12575-27339 1009857 C ATOM 8628 C ASNC 178 9853 24205 -2929 1006747 C ATOM 8713 CA HIS C 189 1303 12391 -28350 1009857 C ATOM 8629 O ASN C 178 8914 24012 -3702 1006747 C ATOM 8714 CB HIS C 189 1139 13677-29143 10013571 C ATOM 8630 N ASP C 179 10934 24892 -3278 1007398 C ATOM 8715 CG HIS C 189 0468 14756 -28366 1009625 C ATOM 8631 CA ASP C 179 11044 25449 -4617 1007398 C ATOM 8716 CD2HISC189 0973 15813-27691 1009625 C ATOM 8632 CB ASP C 179 11639 26868 -4570 1 006569 C ATOM 8717 NDl HIS C 189 -0892 14763-28136 1009625 C ATOM 8633 CG ASPC 179 12991 26932 -3862 1006964 C ATOM 8718 CEl HIS C 189 -1195 15779-27349 1009625 C ATOM 8634 ODl ASP C 179 13504 25871 -3417 1006964 C ATOM 8719 NE2HISC189 -0081 16432-27064 1009625 C ATOM 8635 OD2ASPC179 13536 28060 -3758 1006964 C ATOM 8720 C HIS C 189 1510 11218-29293 1009857 C ATOM 8636 C ASPC 179 11874 24546 -5528 1007398 C ATOM 8721 O HIS C 189 0549 10647 29812 1009857 C ATOM 8637 O ASP C 179 12258 24951 -6618 1007398 C ATOM 8722 N GLU C 190 2765 10860-29509 10011770 C ATOM 8638 N GLN C 180 12128 23315 -5085 1006275 C ATOM 8723 CA GLU C 190 3092 9750-30380 10011770 C ATOM 8639 CA GLNC 180 12911 22343 -5854 1006275 C ATOM 8724 CB GLU C 190 4594 9754-30656 10016277 C ATOM 8640 CB GLNC 180 13724 21466 -4911 1007434 C ATOM 8725 CG GLUC 190 5017 9054-31928 10013719 C ATOM 8641 CG GLNC 180 14584 22217 -3948 1006597 C ATOM 8726 CD GLUC 190 6505 9204-32187 10013719 C ATOM 8642 CD GLNC 180 15570 23105 -4644 1006597 C ATOM 8727 OEl GLUC 190 7307 8679-31385 10013719 C ATOM 8643 OEl GLN C 180 15372 24314 -4734 1006597 C ATOM 8728 OE2GLUC 190 6878 9853-33187 10013719 C ATOM 8644 NE2GLNC180 16645 22509 -5154 1006597 C ATOM 8729 C GLUC 190 2685 8464-29665 10011770 C ATOM 8645 C GLN C 180 12089 21409 -6749 1006275 C ATOM 8730 O GLU C 190 1899 7672-30184 10011770 C ATOM 8646 O GLN C 180 11254 20645 -6266 1006275 C ATOM 8731 N THRC 191 3204 8288-28453 10010347 C ATOM 8647 N LEU C 181 12336 21454 -8051 1006600 C ATOM 8732 CA THRC 191 2942 7106-27636 10010347 C ATOM 8648 CA LEUC 181 11630 20567 -8961 1006600 C ATOM 8733 CB THR C 191 3999 6973 -26536 1008925 C ATOM 8649 CB LEUC 181 11942 20930 10410 1008735 C ATOM 8734 OGl THRC 191 5289 6810-27131 1008925 C ATOM 8650 CG LEUC 181 II 336 19972-11435 1007478 C ATOM 8735 CG2THRC 191 3706 5782 -25663 1008925 C ATOM 8651 CDl LEUC 181 9815 19996 11314 1007478 C ATOM 8736 C THRC 191 1568 7056-26973 10010347 C ATOM 8652 CD2LEUC 181 11774 20358-12837 1007478 C ATOM 8737 O THRC 191 1039 5974 -26724 I 0010347 C ATOM 8653 C LEUC 181 12098 19137 8673 1006600 C ATOM 8738 N ARG C 192 1005 8221 -26670 1008803 C ATOM 8654 O LEUC 181 13302 18870 -8590 1006600 C ATOM 8739 CA ARGC 192 -0306 8312-26029 1008803 C ATOM 8655 N VAL C 182 11149 18222 -8509 1005570 C ATOM 8740 CB ARG C 192 -1311 7395-26735 10015517 C ATOM 8656 CA VALC 182 11492 16836 -8229 1005570 C ATOM 8741 CG ARGC 192 -1617 7828-28152 10015517 C ATOM 8657 CB VALC 182 10722 16317 -7010 1007772 C ATOM 8742 CD ARG C 192 2140 9254-28168 10015517 C ATOM 8658 CGl VALC 182 11061 14852 -6759 1005620 C ATOM 8743 NE ARG C 192 -2269 9777-29524 10015517 C ATOM 8659 CG2VALC182 II 066 17157 -5800 1005620 C ATOM 8744 CZ ARG C 192 -3108 9298-30437 10015517 C ATOM 8660 C VAL C 182 11 176 15937 -9415 1005570 C ATOM 8745 NHl ARG C 192 -3905 8278-30144 10015517 C ATOM 8661 O VAL C 182 11937 15020 -9737 1005570 C ATOM 8746 NH2ARGC 192 -3149 9839 31648 10015517 C ATOM 8662 N THR C 183 10051 16211-10066 1005509 C ATOM 8747 C ARGC 192 -0308 8021 -24526 1008803 C ATOM 8663 CA THRC 183 9627 15411 -11200 1005509 C ATOM 8748 O ARG C 192 -1298 7533-23981 1008803 C ATOM 8664 CB THR C 183 8741 14231-10743 1 008124 C ATOM 8749 N HIS C 193 0805 8317-23865 10010635 C ATOM 8665 OGl THR C 183 9518 13325 -9956 1006783 C ATOM 8750 CA HISC 193 0921 8128-22425 10010635 C ATOM 8666 CG2THRC 183 8155 13495-11941 1006783 C ATOM 8751 CB HISC 193 1252 6664-22089 10011925 C ATOM 8667 C THRC 183 8816 16192-12214 1005509 C ATOM 8752 CG HISC 193 2654 6249-22414 10011925 C ATOM 8668 O THR C 183 7965 17012 -II 856 1005509 C ATOM 8753 CD2HISC193 3775 6971 -22653 10011925 C ATOM 8669 N LYSC 184 9087 15936-13488 1007041 C ATOM 8754 NDl HIS C 193 3037 4926-22458 10011925 C ATOM 8670 CA LYS C 184 8317 16564-14544 1007041 C ATOM 8755 CEl HIS C 193 4332 4850-22708 10011925 C ATOM 8671 CB LYS C 184 9135 17558-15362 1008388 C ATOM 8756 NE2HISC193 4803 6077-22830 10011925 C ATOM 8672 CG LYS C 184 8296 18160-16484 1007572 C ATOM 8757 C HIS C 193 1996 9091 -21926 10010635 C ATOM 8673 CD LYS C 184 9087 19070-17387 1007572 C ATOM 8758 O HIS C 193 2699 9694-22731 10010635 C ATOM 8674 CE LYS C 184 8220 19585-18523 1007572 C ATOM 8759 N GLYC 194 2134 9244-20613 1007204 C ATOM 8675 NZ LYS C 184 9015 20380-19506 1007572 C ATOM 8760 CA GLY C 194 3123 10180-20106 1007204 C ATOM 8676 C LYSC 184 7849 15445-15453 1007041 C ATOM 8761 C GLYC 194 4554 9680 -20084 1007204 C ATOM 8677 O LYSC 184 8621 14556-15804 1007041 C ATOM 8762 O GLYC 194 4797 8478-20160 1007204 C ATOM 8678 N ILEC 185 6576 15484-15815 1006764 C ATOM 8763 N ASNC 195 5502 10610-19990 1007790 C ATOM 8679 CA ILEC 185 6010 14475-16685 1006764 C ATOM 8764 CA ASN C 195 6924 10276-19917 1007790 C ATOM 8680 CB ILEC 185 5136 13475-15890 1008732 C ATOM 8765 CB ASN C 195 7639 10538-21241 10014084 C ATOM 8681 CG2ILEC185 4313 12613-16841 1005624 C ATOM 8766 CG ASN C 195 7226 9589-22325 10014084 C ATOM 8682 CGl ILEC 185 6025 12584-15022 1005624 C ATOM 8767 ODl ASNC 195 7132 8380-22107 10014084 C ATOM 8683 CDl ILEC 185 5248 11707 -14071 1005624 C ATOM 8768 ND2ASNC 195 6993 10125-23517 10014084 C ATOM 8684 C ILE C 185 5150 15174-17712 1006764 C ATOM 8769 C ASN C 195 7576 11161-18873 1007790 C ATOM 8685 O ILEC 185 4432 16123-17387 1006764 C ATOM 8770 O ASNC 195 7261 12350-18780 1007790 C ATOM 8686 N SERC 186 5236 14722-18959 1007384 C ATOM 8771 N VALC 196 8485 10594-18089 1007471 C ATOM 8687 CA SER C 186 4428 15311 -20018 I 007384 C ATOM 8772 CA VALC 196 9175 11391-17090 1007471 C ATOM 8688 CB SERC 186 5265 16285-20851 10010150 C ATOM 8773 CB VALC 196 9816 10524-15998 10010419 C ATOM 8689 OG SERC 186 6534 15739 21 146 1009061 C ATOM 8774 CGl VALC 196 10596 11407-15030 10010419 C ATOM 8690 C SERC 186 3815 14225-20888 1007384 C ATOM 8775 CG2 VALC 196 8742 9744-15263 10010419 C ATOM 8691 O SERC 186 4353 13119-20997 1007384 C ATOM 8776 C VALC 196 10279 12131 -17820 1007471 C ATOM 8692 N TYR C 187 2666 14546-21472 1007124 C ATOM 8777 O VALC 196 11183 11503-18370 1007471 C ATOM 8693 CA TYRC 187 1943 13617-22322 1007124 C ATOM 8778 N ASN C 197 10203 13459-17834 1008735 C ATOM 8694 CB TYRC 187 0494 14068-22473 10013232 C ATOM 8779 CA ASN C 197 11213 14269-18507 1008735 C ATOM 8695 CG TYR C 187 0354 13074-23218 1008653 C ATOM 8780 CB ASN C 197 10596 15549-19065 1009461 C ATOM 8696 CDlTYRC 187 -0686 11850 -22642 1008653 C ATOM 8781 CG ASN C 197 9311 15299-19814 1009461 C ATOM 8697 CEl TYRC 187 -1454 10918-23327 1008653 C ATOM 8782 ODl ASN C 197 9230 14399-20650 1009461 C ATOM 8698 CD2TYRC 187 -0811 13343-24505 1008653 C ATOM 8783 ND2 ASN C 197 8294 16104-19526 1009461 C ATOM 8699 CE2 TYRC 187 -1579 12417-25202 1008653 C ATOM 8784 C ASN C 197 12323 14652-17548 1008735 C ATOM 8700 CZ TYR C 187 -1898 11208 -24607 1008653 C ATOM 8785 O ASN C 197 13479 14783-17941 1008735 C ATOM 8701 OH TYRC 187 2667 10287-25278 1008653 C ATOM 8786 N PHE C 198 11964 14832-16285 1008218 C 65251/C766

ATOM 8787 CA PHEC 198 12934 15227-15286 1008218 C ATOM 8872 CD ARG C 207 15828 5578 0700 1008372 C ATOM 8788 CB PHEC 198 12832 16732-15046 1007950 C ATOM 8873 NE ARG C 207 16640 6701 0238 1008372 C ATOM 8789 CG PHEC 198 13827 17248-14063 1007950 C ATOM 8874 CZ ARG C 207 17263 7552 1051 1008372 C ATOM 8790 CDl PHEC 198 15068 17694-14485 1007950 C ATOM 8875 NHl ARG C 207 17159 7406 2370 1008372 C ATOM 8791 CD2PHEC198 13544 17240-12706 1007950 C ATOM 8876 NH2 ARG C 207 17992 8544 0548 1008372 C ATOM 8792 CElPHEC 198 16017 18124-13567 1007950 C ATOM 8877 C ARG C 207 11 118 6372 0265 1005841 C ATOM 8793 CE2PHEC 198 14485 17666-11779 1007950 C ATOM 8878 O ARG C 207 11 103 6875 0857 1005841 C ATOM 8794 CZ PHEC 198 15726 18110-12211 1007950 C ATOM 8879 N SER C 208 10152 6577 -1 158 1006028 C ATOM 8795 C PHEC 198 12746 14506-13961 1008218 C ATOM 8880 CA SER C 208 8997 7416 -0848 1006028 C ATOM 8796 O PHEC 198 11626 14205-13552 1008218 C ATOM 8881 CB SER C 208 9033 8717 -1644 1008674 C ATOM 8797 N ARG C 199 13860 14240-13294 1007637 C ATOM 8882 OG SER C 208 7956 9549 -1255 1008674 C ATOM 8798 CA ARGC 199 13833 13598-11996 1007637 C ATOM 8883 C SER C 208 7710 6670 -1 161 1006028 C ATOM 8799 CB ARGC 199 13894 12082-12116 1008998 C ATOM 8884 O SER C 208 6999 6989 -2122 1006028 C ATOM 8800 CG ARGC 199 13909 11419-10754 1008998 C ATOM 8885 N PRO C 209 7394 5662 -0336 1006044 C ATOM 8801 CD ARGC 199 12535 11462-10122 1008998 C ATOM 8886 CD PRO C 209 8186 5352 0870 1005508 C ATOM 8802 NE ARGC 199 11843 10198-10342 1008998 C ATOM 8887 CA PRO C 209 6223 4785 -0414 1006044 C ATOM 8803 CZ ARGC 199 10544 10078-10594 1008998 C ATOM 8888 CB PRO C 209 6236 4077 0937 1005508 C ATOM 8804 NHl ARG C 199 9774 11153-10667 1008998 C ATOM 8889 CG PRO C 209 7681 3979 1241 1005508 C ATOM 8805 NH2ARGC199 10014 8876-10772 1008998 C ATOM 8890 C PRO C 209 4911 5508 -0636 1006044 C ATOM 8806 C ARG C 199 15037 14072-11205 1007637 C ATOM 8891 O PRO C 209 3982 4951 -1223 1006044 C ATOM 8807 O ARG C 199 16171 13832-11599 1007637 C ATOM 8892 N HIS C 210 4832 6751 -0170 1006145 C ATOM 8808 N ALA C 200 14792 14749-10091 1007519 C ATOM 8893 CA HIS C 210 3592 7498 -0284 1006145 C ATOM 8809 CA ALA C 200 15883 15242 -9269 1007519 C ATOM 8894 CB HIS C 210 3327 8204 1037 1006374 C ATOM 8810 CB ALA C 200 15330 15941 -8031 1006311 C ATOM 8895 CG HIS C 210 3 140 7254 2177 1006374 C ATOM 8811 C ALA C 200 16803 14088 8872 1007519 C ATOM 8896 CD2HISC210 3955 6923 3206 1006374 C ATOM 8812 O ALA C 200 16350 13001 -8516 1007519 C ATOM 8897 NDl HIS C 210 2020 6460 2301 I 006374 C ATOM 8813 N ASP C 201 18102 14338 -8949 1009672 C ATOM 8898 CEl HIS C 210 2153 5680 3359 1006374 C ATOM 8814 CA ASP C 201 19112 13347 -8615 1009672 C ATOM 8899 NE2HISC210 3318 5941 3925 1006374 C ATOM 8815 CB ASP C 201 20499 13925 -8887 10012074 C ATOM 8900 C HIS C 210 1471 8446 -1455 1006145 C ATOM 8816 CG ASP C 201 20681 15300 -8273 10012074 C ATOM 8901 O HIS C 210 2519 9223 -1536 1006145 C ATOM 8817 ODl ASP C 201 20015 16249 -8741 10012074 C ATOM 8902 N THR C 211 4442 8391 -2359 1007209 C ATOM 8818 OD2ASPC201 21480 15429 -7321 10012074 C ATOM 8903 CA THR C 211 4382 9204 -3563 1007209 C ATOM 8819 C ASP C 201 19053 12857 -7172 1009672 C ATOM 8904 CB THR C 211 5779 9470 -4154 1007407 C ATOM 8820 O ASP C 201 19431 11721 -6890 1009672 C ATOM 8905 OGl THR C 211 6568 10221 -3221 1007407 C ATOM 8821 N TRP C 202 18582 13703 -6260 10010279 C ATOM 8906 CG2 THRC 211 5652 10254 -5448 1007407 C ATOM 8822 CA TRP C 202 18515 13329 -4843 10010279 C ATOM 8907 C THR C 211 3603 8284 -4498 1007209 C ATOM 8823 CB TRP C 202 18651 14570 -3954 1008313 C ATOM 8908 O THR C 211 3980 7129 -4686 1007209 C ATOM 8824 CG TRP C 202 17677 15677 ^l 256 100 S313 C ATOM 8909 N PRO C 212 2502 8774 -5081 1008323 C ATOM 8825 CD2TRPC202 16362 15839 -3712 1008313 C ATOM 8910 CD PRO C 212 2029 10166 -4986 1006757 C ATOM 8826 CE2TRPC202 15828 17031 -4255 1008313 C ATOM 8911 CA PRO C 212 1657 7990 -5994 1008323 C ATOM 8827 CE3TRPC202 15583 15094 -2819 1008313 C ATOM 8912 CB PRO C 212 0751 9046 -6615 1006757 C ATOM 8828 CDl TRP C 202 17879 16743 -5086 1008313 C ATOM 8913 CG PROC212 0608 10057 -5500 1006757 C ATOM 8829 NEl TRP C 202 16774 17563 -5088 1008313 C ATOM 8914 C PRO C 212 2408 7178 -7052 1008323 C ATOM 8830 CZ2 TRP C 202 14552 17494 -3933 1008313 C ATOM 8915 O PRO C 212 3394 7648 -7622 1008323 C ATOM 8831 CZ3TRPC202 14316 15555 -2498 1008313 C ATOM 8916 N GLY C 213 1931 5961 -7313 1007837 C ATOM 8832 CH2TRPC202 13813 16747 -3055 1008313 C ATOM 8917 CA GLY C 213 2555 5098 -8309 1007837 C ATOM 8833 C TRP C 202 17271 12564 -4401 10010279 C ATOM 8918 C GLY C 213 2063 5380 -9718 1007837 C ATOM 8834 O TRP C 202 17208 12077 -3271 10010279 C ATOM 8919 O GLY C 213 1220 6258 -9915 1007837 C ATOM 8835 N PHE C 203 16294 12443 -5288 1007628 C ATOM 8920 N ASN C 214 2571 4635-10698 1007562 C ATOM 8836 CA PHE C 203 15051 11772 -4948 1007628 C ATOM 8921 CA ASN C 214 2192 4828-12101 1007562 C ATOM 8837 CB PHE C 203 13879 12579 -5506 1006561 C ATOM 8922 CB ASN C 214 0697 4604-12325 10010320 C ATOM 8838 CG PHE C 203 12538 12095 -5055 1006561 C ATOM 8923 CG ASN C 214 0155 3467-11522 1009737 C ATOM 8839 CDl PHE C 203 12136 12258 -3731 1006561 C ATOM 8924 ODl ASN C 214 0909 2640-11016 1009737 C ATOM 8840 CD2PHEC203 11667 11490 -5954 1006561 C ATOM 8925 ND2ASNC214 -1 167 3407-11401 1009737 C ATOM 8841 CEl PHE C 203 10879 11826 -3308 I 006561 C ATOM 8926 C ASN C 214 2499 6262-12479 1007562 C ATOM 8842 CE2PHEC203 10407 11052 -5543 1006561 C ATOM 8927 O ASN C 214 1643 6967-13026 1007562 C ATOM 8843 CZ PHE C 203 10009 11221 -4216 1006561 C ATOM 8928 N ASP C 215 3718 6696-12179 1008935 C ATOM 8844 C PHE C 203 14957 10342 -5451 1007628 C ATOM 8929 CA ASP C 215 4121 8059-12476 1008935 C ATOM 8845 O PHE C 203 14768 10118 6644 1007628 C ATOM 8930 CB ASP C 215 4398 8210-13964 10018094 C ATOM 8846 N ASN C 204 15101 9376 -4548 1007386 C ATOM 8931 CG ASP C 215 5432 7229-14451 I 0010232 C ATOM 8847 CA ASN C 204 14977 7964 -4914 1007386 C ATOM 8932 ODl ASP C 215 6550 7214-13894 10010232 C ATOM 8848 CB ASN C 204 15886 7081 -4039 10011125 C ATOM 8933 OD2ASPC215 5128 6467-15385 10010232 C ATOM 8849 CG ASN C 204 15590 5593 -4200 10011125 C ATOM 8934 C ASP C 215 3017 9010-12050 1008935 C ATOM 8850 ODl ASN C 204 14511 5137 -3835 10011125 C ATOM 8935 O ASP C 215 2404 9687-12882 1008935 C ATOM 8851 ND2ASNC204 16524 4840 -4775 10011125 C ATOM 8936 N TYRC 216 2755 9024-10745 1005738 C ATOM 8852 C ASN C 204 13510 7654 -4644 1007386 C ATOM 8937 CA TYR C 216 1748 9896 10155 1005738 C ATOM 8853 O ASN C 204 13117 7436 -3501 1007386 C ATOM 8938 CB TYR C 216 2209 11358-10242 1007592 C ATOM 8854 N ILE C 205 12697 7655 -5694 1006717 C ATOM 8939 CG TYRC216 3594 11596 -9694 1005467 C ATOM 8855 CA ILE C 205 11263 7411 -5544 1006717 C ATOM 8940 CD1 TYRC216 4714 11081 -10340 1005467 C ATOM 8856 CB ILE C 205 10554 7441 -6905 1005223 C ATOM 8941 CEl TYR C 216 5993 11269 -9827 1005467 C ATOM 8857 CG2ILEC205 10703 6091 -7598 1005223 C ATOM 8942 CD2TYRC216 3787 12316 -8511 1005467 C ATOM 8858 CGl ILE C 205 9075 7764 -6703 1005223 C ATOM 8943 CE2TYRC216 5060 12516 -7987 1005467 C ATOM 8859 CDl ILE C 205 8380 8276 -7958 1005223 C ATOM 8944 CZ TYR C 216 6160 11989 -8653 1005467 C ATOM 8860 C ILE C 205 10905 6105 -4831 1006717 C ATOM 8945 OH TYR C 216 7430 12179 -8157 1005467 C ATOM 8861 O ILE C 205 9783 5941 -4359 1006717 C ATOM 8946 C TYR C 216 0356 9769-10773 1005738 C ATOM 8862 N SER C 206 11855 5179 -4754 1008368 C ATOM 8947 O TYR C 216 -0391 10750-10830 1005738 C ATOM 8863 CA SER C 206 11612 3910 -4080 1008368 C ATOM 8948 N ASN C 217 -0001 8565-11214 1006508 C ATOM 8864 CB SER C 206 12687 2896 -4460 1008938 C ATOM 8949 CA ASN C 217 -I 309 8338-11824 1006508 C ATOM 8865 OG SER C 206 12606 2590 -5837 1008938 C ATOM 8950 CB ASN C 217 -2427 8499-10784 1007748 C ATOM 8866 C SER C 206 11602 4105 -2569 1008368 C ATOM 8951 CG ASN C 217 -2329 7491 -9651 1007221 C ATOM 8867 O SER C 206 11046 3296 -1831 1008368 C ATOM 8952 ODl ASN C 217 -2309 7863 -8477 1007221 C ATOM 8868 N ARG C 207 12224 5185 -2111 1005841 C ATOM 8953 ND2ASNC217 -2276 6211 -9997 1007221 C ATOM 8869 CA ARG C 207 12274 5475 0692 1005841 C ATOM 8954 C ASN C 217 -1512 9354-12940 1006508 C ATOM 8870 CB ARG C 207 13608 6127 -0326 1008372 C ATOM 8955 O ASN C 217 -2627 9842-13160 1006508 C ATOM 8871 CG ARG C 207 14769 5152 0305 1008372 C ATOM 8956 N PHE C 218 -0434 9668-13651 1006952 C 65251/C766

ATOM 8957 CA PHEC 218 -0512 10656-14721 1006952 C ATOM 9042 O LYS C 226 -11002 16965-21531 1008918 C ATOM 8958 CB PHEC218 0851 10890-15353 1008943 C ATOM 9043 N GLU C 227 -11043 15008-20418 1006766 C ATOM 8959 CG FHE C 218 0836 11969-16382 1008595 C ATOM 9044 CA GLU C 227 -12491 14843-20512 1006766 C ATOM 8960 CDl PHE C 218 0925 13303-16009 1008595 C ATOM 9045 CB GLU C 227 -12934 13563-19799 10013241 C ATOM 8961 CD2PHEC218 0665 11661 17722 1008595 C ATOM 9046 CG GLU C 227 -14417 13262-19957 10010821 C ATOM 8962 CEl PHE C 218 0840 14319-16958 1008595 C ATOM 9047 CD GLU C 227 -14922 12206-18983 10010821 C ATOM 8963 CE2 PHEC 218 0579 12668-18678 1008595 C ATOM 9048 OEl GLU C 227 -14320 U 112-18915 10010821 ATOM 8964 CZ PHE C 218 0667 13999-18294 1008595 C C ATOM 8965 C PHE C 218 -1499 10332-15831 1006952 C ATOM 9049 OE2 GLU C 227 -15931 12474-18291 10010821 ATOM 8966 O PHE C 218 -2339 11164-16178 1006952 C C ATOM 8967 N ASN C 219 -1387 9136-16404 1006912 C ATOM 9050 C GLU C 227 -13187 16035-19869 1006766 C ATOM 8968 CA ASN C 219 -2296 8741 -17472 1006912 C ATOM 9051 O GLU C 227 -14094 16621 20447 1006766 C ATOM 8969 CB ASN C 219 -2036 7299-17908 1008857 C ATOM 9052 N THR C 228 -12748 16394-18669 10010240 C ATOM 8970 CG ASN C 219 -0618 7085-18382 1008020 C ATOM 9053 CA THR C 228 -13336 17510-17941 10010240 C ATOM 8971 ODl ASN C 219 -0016 7968-18988 1008020 C ATOM 9054 CB THR C 228 12692 17666-16559 10010251 C ATOM 8972 ND2ASNC219 -0077 5903-18121 1008020 C ATOM 9055 OGl THR C 228 -12848 16447-15824 1008850 C ATOM 8973 C ASN C 219 -3740 8887-17002 1006912 C ATOM 9056 CG2 THR C 228 -13349 18813-15793 1008850 C ATOM 8974 O ASN C 219 -4590 9392-17737 1006912 C ATOM 9057 C THR C 228 -13197 18833-18679 10010240 C ATOM 8975 N PHE C 220 -4016 8458-15772 1006746 C ATOM 9058 O THR C 228 -14110 19661 -18665 10010240 C ATOM 8976 CA PHE C 220 -5365 8564-15235 1006746 C ATOM 9059 N LEU C 229 -12051 19039-19313 10011137 C ATOM 8977 CB PHE C 220 5426 8034 13802 1006494 C ATOM 9060 CA LEU C 229 -1183720276-20037 10011137 C ATOM 8978 CG PHE C 220 -6699 8400-13078 1005792 C ATOM 9061 CB LEU C 229 -1038020382-20489 1007764 C ATOM 8979 CDl PHE C 220 -7858 7649 13253 1005792 C ATOM 9062 CG LEU C 229 -10000 21662 -21246 1004952 C ATOM 8980 CD2PHEC220 6757 9540 12275 1005792 C ATOM 9063 CDl LEU C 229 -10586 22894-20570 1004952 C ATOM 8981 CEl PHE C 220 -9060 8029-12640 1005792 C ATOM 9064 CD2LEUC229 -8478 21745-21316 1004952 C ATOM 8982 CE2PHEC220 -7949 9930 -11662 1005792 C ATOM 9065 C LEU C 229 -12779 20366 -21232 10011137 C ATOM 8983 CZ PHE C 220 -9103 9173-11845 1005792 C ATOM 9066 O LEU C 229 -13330 21430-21511 10011137 C ATOM 8984 C PHE C 220 -5841 10009-15238 1006746 C ATOM 9067 N GLU C 230 -12975 19248-21928 1008296 C ATOM 8985 O PHE C 220 -6896 10324-15794 1006746 C ATOM 9068 CA GLU C 230 -13863 19225-23083 1008296 C ATOM 8986 N TRP C 221 -5061 10884-14607 1005574 C ATOM 9069 CB GLU C 230 -13836 17850-23748 10014241 C ATOM 8987 CA TRP C 221 -5430 12291 -14518 1005574 C ATOM 9070 CG GLU C 230 -12529 17552-24455 10010687 C ATOM 8988 CB TRP C 221 -4484 13021 -13558 1005466 C ATOM 9071 CD GLU C 230 -12528 16200-25145 10010687 C ATOM 8989 CG TRP C 221 4734 12684-12116 1004781 C ATOM 9072 OEl GLU C 230 -13470 15937 -25922 10010687 ATOM 8990 CD2 TRP C 221 -5945 12917 11384 1004781 C C ATOM 8991 CE2TRPC221 -5764 12370-10091 1004781 C ATOM 9073 OE2GLUC230 -11586 15405-24919 10010687 ATOM 8992 CE3TRPC221 -7169 13529-11697 1004781 C C ATOM 8993 CDl TRP C 221 -3884 12030-11258 1004781 C ATOM 9074 C GLU C 230 -15288 19587-22683 1008296 C ATOM 8994 NEl TRP C 221 ■4501 11836-10039 1004781 C ATOM 9075 O GLU C 230 -15932 20410-23337 1008296 C ATOM 8995 CZ2TRPC221 6759 12417 -9113 1004781 C ATOM 9076 N GLU C 231 -15776 18981-21607 1008807 C ATOM 8996 CZ3TRPC221 -8167 13573-10720 1004781 C ATOM 9077 CA GLU C 231 -17126 19257-21118 1008807 C ATOM 8997 CH2TRPC221 -7952 13019 -9443 1004781 C ATOM 9078 CB GLU C 231 -17438 18390-19896 10017477 C ATOM 8998 C TRP C 221 -5472 13009 -15854 1005574 C ATOM 9079 CG GLU C 231 -17265 16899-20122 10015101 C ATOM 8999 O TRP C 221 -6426 13733-16166 1005574 C ATOM 9080 CD GLU C 231 -18277 16330-21094 10015101 C ATOM 9000 N TYR C 222 -4442 12814-16676 1006850 C ATOM 9081 OEl GLU C 231 -18380 16854-22225 10015101 ATOM 9001 CA TYR C 222 -4415 13466-17976 1006850 C C ATOM 9002 CB TYR C 222 -3273 12927-18830 1009607 C ATOM 9082 OE2GLUC231 -18966 15353-20727 10015101 ATOM 9003 CG TYR C 222 -3370 13410-20255 1009464 C C ATOM 9004 CDl TYR C 222 -2989 14707-20603 1009464 C ATOM 9083 C GLU C 231 17246 20729 -20734 1008807 C ATOM 9005 CEl TYR C 222 -3153 15178-21899 1009464 C ATOM 9084 O GLU C 231 -18224 21390-21075 1008807 C ATOM 9006 CD2TYRC222 -3915 12595-21246 1009464 C ATOM 9085 N ILE C 232 ■1624621235 -20020 10010152 C ATOM 9007 CE2TYRC222 -4085 13057 -22544 1009464 C ATOM 9086 CA ILE C 232 -1624622625-19586 10010152 C ATOM 9008 CZ TYR C 222 -3705 14345-22862 1009464 C ATOM 9087 CB ILE C 232 -14969 22950-18773 10011985 C ATOM 9009 OH TYR C 222 -3894 14797 -24142 1009464 C ATOM 9088 CG2 ILE C 232 -14803 24453 -18627 1008990 C ATOM 9010 C TYR C 222 -5724 13217-18711 1006850 C ATOM 9089 CGl ILE C 232 -15049 22298 -17393 1008990 C ATOM 9011 O TYR C 222 -6399 14144-19168 1006850 C ATOM 9090 CDl ILE C 232 -13835 22550-16530 1008990 C ATOM 9012 N SER C 223 -6071 11942-18815 1008171 C ATOM 9091 C ILE C 232 16342 23595-20761 10010152 C ATOM 9013 CA SER C 223 -7276 11527-19501 1008171 C ATOM 9092 O ILE C 232 16945 24666 -20645 10010152 C ATOM 9014 CB SER C 223 -7346 10007-19518 1008537 C ATOM 9093 N ASN C 233 -1575723219-21892 10010736 C ATOM 9015 OG SER C 223 -8573 9582 -20067 1008399 C ATOM 9094 CA ASN C 233 -1577424087-23060 10010736 C ATOM 9016 C SER C 223 -8553 12095-18898 1008171 C ATOM 9095 CB ASN C 233 -1457923782-23968 10011055 C ATOM 9017 O SER C 223 -9383 12651 -19615 1008171 C ATOM 9096 CG ASN C 233 -13261 24229-23365 1009947 C ATOM 9018 N LEU C 224 -8711 11957-17585 1006980 C ATOM 9097 ODl ASN C 233 -13204 25221 -22638 1009947 C ATOM 9019 CA LEU C 224 9911 12447-16917 1006980 C ATOM 9098 ND2 ASN C 233 -1218923508-23678 1009947 C ATOM 9020 CB LEU C 224 -9959 11944-15475 1009380 C ATOM 9099 C ASN C 233 -1705824066-23881 10010736 C ATOM 9021 CG LEU C 224 11188 12409 14696 1007104 C ATOM 9100 O ASN C 233 -1724724923 -24744 10010736 C ATOM 9022 CDl LEU C 224 -12465 12039-15436 1007104 C ATOM 9101 N LYSC234 -17942 23106 -23626 1009485 C ATOM 9023 CD2 LEU C 224 -11154 11782-13321 1007104 C ATOM 9102 CA LYS C 234 -19193 23041 -24375 1009485 C ATOM 9024 C LEU C 224 -10007 13968-16942 1006980 C ATOM 9103 CB LYS C 234 -1993421739-24073 1008261 C ATOM 9025 O LEU C 224 -11103 14527-16960 1006980 C ATOM 9104 CG LYS C 234 -19263 20545 -24740 1008261 C ATOM 9026 N MET C 225 -8859 14637-16938 1009764 C ATOM 9105 CD LYS C 234 -20010 19240-24507 1008261 C ATOM 9027 CA MET C 225 8850 16090-16980 1009764 C ATOM 9106 CE LYS C 234 -19318 18097-25241 1008261 C ATOM 9028 CB MET C 225 -7501 16624-16536 10010679 C ATOM 9107 NZ LYS C 234 -19922 16775 24944 1008261 C ATOM 9029 CG MET C 225 -7250 16397-15075 1007551 C ATOM 9108 C LYS C 234 -2006924257 -24097 1009485 C ATOM 9030 SD MET C 225 -5760 17204-14537 1007551 C ATOM 9109 O LYS C 234 -2061724842 -25027 1009485 C ATOM 9031 CE MET C 225 -6213 18936-14787 1007551 C ATOM 9110 N ASN C 235 -20215 24636-22830 10010385 C ATOM 9032 C MET C 225 -9149 16543-18392 1009764 C ATOM 9111 CA ASN C 235 -20981 25839 -22510 10010385 C ATOM 9033 O MET C 225 -9813 17558-18606 1009764 C ATOM 9112 CB ASN C 235 -21343 25907 -21018 10011224 C ATOM 9034 N LYS C 226 -8654 15782-19361 1008918 C ATOM 9113 CG ASN C 235 -2202927222-20641 10011224 C ATOM 9035 CA LYS C 226 -8903 16102-20755 1008918 C ATOM 9114 ODl ASN C 235 -2158428286-21071 10011224 ATOM 9036 CB LYS C 226 -8226 15076-21658 10013693 C C ATOM 9037 CG LYS C 226 -8440 15327-23130 1008839 C ATOM 9115 ND2 ASN C 235 -23095 27161 -19838 10011224 ATOM 9038 CD LYS C 226 -7867 14193-23956 1008839 C C ATOM 9039 CE LYS C 226 -8291 14309-25400 1008839 C ATOM 9116 C ASN C 235 -1997426933-22856 10010385 C ATOM 9040 NZ LYS C 226 -7761 13175-26188 1008839 C ATOM 9117 O ASN C 235 -1897027102-22166 10010385 C ATOM 9041 C LYS C 226 -10416 16059-20943 1008918 C ATOM 9118 N ASP C 236 -20235 27659-23935 10015902 C 65251/C766

ATOM 9119 CA ASP C 236 -19330 28702-24402 10015902 C ATOM 9204 O THR C 247 -0450 19160 -4604 1004903 C ATOM 9120 CB ASP C 236 -1986429283-25714 10013363 C ATOM 9205 N GLY C 248 -1479 19198 -2597 1005161 C ATOM 9121 CG ASP C 236 -18772 29888-26570 10013363 C ATOM 9206 CA GLY C 248 -0237 19113 -1850 1005161 C ATOM 9122 ODl ASP C 236 -18235 30950-26197 10013363 C ATOM 9207 C GLY C 248 -0438 19459 0381 1005161 C ATOM 9123 OD2ASPC236 -1844729292-27617 10013363 C ATOM 9208 O GLY C 248 -1573 19596 0091 1005161 C ATOM 9124 C ASP C 236 -1902929833-23412 10015902 C ATOM 9209 N CYS C 249 0657 19602 0357 1005784 C ATOM 9125 O ASP C 236 -1816730669 -23680 10015902 C ATOM 9210 CA CYS C 249 0555 19921 1774 1005784 C ATOM 9126 N SER C 237 -19721 29868-22276 10010813 C ATOM 9211 CB CYS C 249 0539 18632 2607 1004023 C ATOM 9127 CA SER C 237 -19475 30920-21285 10010813 C ATOM 9212 SG CYS C 249 2131 17774 2665 1005900 C ATOM 9128 CB SER C 237 -2077731328 20589 10010374 C ATOM 9213 C CYS C 249 1709 20806 2225 1005784 C ATOM 9129 OG SER C 237 -21185 30351-19647 10010374 C ATOM 9214 O CYS C 249 2605 21 140 1440 1005784 C ATOM 9130 C SER C 237 -18453 30480-20231 10010813 C ATOM 9215 N TYR C 250 1695 21 166 3503 1005174 C ATOM 9131 O SER C 237 18182 31213-19279 10010813 C ATOM 9216 CA TYR C 250 2731 22030 4042 1005174 C ATOM 9132 N THR C 238 -1789429284-20407 10010021 C ATOM 9217 CB TYR C 250 2391 23470 3724 1003590 C ATOM 9133 CA THR C 238 -16902 28743-19480 10010021 C ATOM 9218 CG TYR C 250 1095 23903 4371 1002625 C ATOM 9134 CB THR C 238 17380 27427-18840 1009652 C ATOM 9219 CDl TYR C 250 1082 24471 5640 1002625 C ATOM 9135 OGl THR C 238 -18742 27564-18424 1009652 C ATOM 9220 CEl TYR C 250 -0117 24870 6241 1002625 C ATOM 9136 CG2THRC238 -1651627085-17627 1009652 C ATOM 9221 CD2TYRC250 -0126 23735 3712 1002625 C ATOM 9137 C THR C 238 -1560428450-20222 10010021 C ATOM 9222 CE2TYRC250 -1327 24127 4302 1002625 C ATOM 9138 O THR C 238 -1452628437-19629 10010021 C ATOM 9223 CZ TYR C 250 1312 24696 5564 1002625 C ATOM 9139 N LYS C 239 -1572828208-21524 10011091 C ATOM 9224 OH TYR C 250 -2483 25114 6158 1002625 C ATOM 9140 CA LYS C 239 -14591 27904-22385 10011091 C ATOM 9225 C TYR C 250 2896 21928 5542 1005174 C ATOM 9141 CB LYS C 239 -14818 28509-23778 10011938 C ATOM 9226 O TYR C 250 1960 21591 6265 1005174 C ATOM 9142 CG LYS C 239 -1372728184 -24792 10011938 C ATOM 9227 N GLU C 251 4102 22248 5990 1006966 C ATOM 9143 CD LYS C 239 -1413228589-26201 10011938 C ATOM 9228 CA GLU C 251 4449 22272 7396 1006966 C ATOM 9144 CE LYS C 239 -1534627801 -26667 10011938 C ATOM 9229 CB GLU C 251 5322 21075 7772 10013616 C ATOM 9145 NZ LYS C 239 -1575328176-28046 10011938 C ATOM 9230 CG GLU C 251 4627 20111 8719 1008978 C ATOM 9146 C LYS C 239 -1327628405-21794 10011091 C ATOM 9231 CD GLU C 251 5542 19007 9232 1008978 C ATOM 9147 O LYS C 239 -13125 29588-21496 10011091 C ATOM 9232 OEl GLU C 251 6601 19328 9820 1008978 C ATOM 9148 N THR C 240 -12331 27488-21620 1007606 C ATOM 9233 OE2GLUC251 5196 17815 9055 1008978 C ATOM 9149 CA THR C 240 -11035 27826-21052 1007606 C ATOM 9234 C GLU C 251 5230 23564 7521 1006966 C ATOM 9150 CB THR C 240 10923 27346-19597 10011302 C ATOM 9235 O GLU C 251 6458 23567 7478 1006966 C ATOM 9151 OGl THR C 240 -12022 27858 18838 10011302 C ATOM 9236 N THR C 252 4495 24666 7629 1005504 C ATOM 9152 CG2THRC240 -9621 27824 -18981 10011302 C ATOM 9237 CA THR C 252 5070 26004 7755 1005504 C ATOM 9153 C THR C 240 -9884 27204 -21822 1007606 C ATOM 9238 CB THR C 252 4193 27029 7007 1006580 C ATOM 9154 O THR C 240 -1003326169 -22476 1007606 C ATOM 9239 OGl THR C 252 3984 26588 5662 1006580 C ATOM 9155 N THR C 241 -8727 27845-21717 1007868 C ATOM 9240 CG2 THR C 252 4860 28389 6984 1006580 C ATOM 9156 CA THR C 241 -7515 27390-22377 1007868 C ATOM 9241 C THR C 252 5125 26383 9239 1005504 C ATOM 9157 CB THR C 241 -641028447-22252 10010914 C ATOM 9242 O THR C 252 4144 26876 9799 1005504 C ATOM 9158 OGl THR C 241 -6940 29732 -22599 1006884 C ATOM 9243 N GLY C 253 6269 26165 9876 1005847 C ATOM 9159 CG2THRC241 -5226 28097 -23156 1006884 C ATOM 9244 CA GLY C 253 6356 26466 11292 1005847 C ATOM 9160 C THR C 241 -6991 26106-21737 1007868 C ATOM 9245 C GLY C 253 5389 25569 12052 1005847 C ATOM 9161 O THR C 241 -661025160 -22429 1007868 C ATOM 9246 O GLY C 253 5393 24350 11869 1005847 C ATOM 9162 N SER C 242 -697826089 -20406 1008512 C ATOM 9247 N LEU C 254 4556 26159 12901 1006158 C ATOM 9163 CA SER C 242 -645824947 -19669 1008512 C ATOM 9248 CA LEU C 254 3584 25387 13661 1006158 C ATOM 9164 CB SER C 242 -497225160-19396 10013102 C ATOM 9249 CB LEU C 254 3048 26184 14845 1003625 C ATOM 9165 OG SER C 242 -4781 26312-18589 10010354 C ATOM 9250 CG LEU C 254 3978 26449 16014 1003625 C ATOM 9166 C SER C 242 -715424664 -18343 1008512 C ATOM 9251 CDl LEU C 254 3161 27060 17123 1003625 C ATOM 9167 O SER C 242 -7961 25456-17849 1008512 C ATOM 9252 CD2 LEU C 254 4636 25175 16467 1003625 C ATOM 9168 N LEU C 243 -679823519-17770 1006736 C ATOM 9253 C LEU C 254 2398 24989 12802 1006158 C ATOM 9169 CA LEU C 243 -734423069-16503 1006736 C ATOM 9254 O LEU C 254 1762 23970 13066 1006158 C ATOM 9170 CB LEU C 243 -8361 21961 -16758 10011922 C ATOM 9255 N LEU C 255 2089 25801 11793 1004824 C ATOM 9171 CG LEU C 243 -923621563 -15577 1009535 C ATOM 9256 CA LEU C 255 0962 25533 10909 1004824 C ATOM 9172 CDl LEU C 243 -10005 22779 15090 1009535 C ATOM 9257 CB LEU C 255 0648 26761 10065 1004235 C ATOM 9173 CD2LEUC243 -10189 20454-16003 1009535 C ATOM 9258 CG LEU C 255 0459 28072 10830 1004235 C ATOM 9174 C LEU C 243 -618822537-15648 1006736 C ATOM 9259 CDl LEU C 255 0070 29166 9856 1004235 C ATOM 9175 O LEU C 243 -528021868-16157 1006736 C ATOM 9260 CD2 LEU C 255 -0605 27917 11900 1004235 C ATOM 9176 N SER C 244 -6213 22841 -14353 1006279 C ATOM 9261 C LEU C 255 1211 24343 9987 1004824 C ATOM 9177 CA SER C 244 -515822384-13457 1006279 C ATOM 9262 O LEU C 255 2353 24051 9613 1004824 C ATOM 9178 CB SER C 244 -4243 23545 -13073 1007479 C ATOM 9263 N PHE C 256 0132 23651 9630 1004921 C ATOM 9179 OG SER C 244 -348923996 -14173 1007694 C ATOM 9264 CA PHE C 256 0225 22493 8755 1004921 C ATOM 9180 C SERC 244 -5665 21746-12172 1006279 C ATOM 9265 CB PHE C 256 0794 21290 9518 1004720 C ATOM 9181 O SER C 244 -665922190-11571 1006279 C ATOM 9266 CG PHE C 256 -0102 20769 10613 1004421 C ATOM 9182 N LEUC 245 -4965 20699 -11752 1006079 C ATOM 9267 CDl PHE C 256 0944 19693 10387 1004421 C ATOM 9183 CA LEU C 245 -5293 20022-10509 1006079 C ATOM 9268 CD2PHEC256 0095 21350 11884 1004421 C ATOM 9184 CB LEU C 245 -5389 18509-10708 1007651 C ATOM 9269 CEl PHE C 256 -1757 19206 11403 1004421 C ATOM 9185 CG LEU C 245 -5643 17743 -9404 1006050 C ATOM 9270 CE2PHEC256 -0915 20860 12909 1004421 C ATOM 9186 CDl LEU C 245 -6916 18257 -8746 1006050 C ATOM 9271 CZ PHE C 256 -1741 19793 12665 1004421 C ATOM 9187 CD2LEUC245 -5741 16256 -9693 1006050 C ATOM 9272 C PHE C 256 -1 144 22161 8181 1004921 C ATOM 9188 C LEU C 245 -416420338 -9539 1006079 C ATOM 9273 O PHE C 256 -2163 22319 8850 1004921 C ATOM 9189 O LEU C 245 -3052 19827 -9683 1006079 C ATOM 9274 N GLY C 257 -1 164 21714 6929 1004197 C ATOM 9190 N ILE C 246 -444721197 -8565 1005476 C ATOM 9275 CA GLY C 257 -241721370 6286 1004197 C ATOM 9191 CA ILE C 246 -344621584 -7577 1005476 C ATOM 9276 C GLY C 257 -2187 20770 4911 1004197 C ATOM 9192 CB ILE C 246 -347723112 -7322 1006826 C ATOM 9277 O GLY C 257 -1037 20590 4483 1004197 C ATOM 9193 CG2ILEC246 -2348 23517 -6381 1005130 C ATOM 9278 N SER C 258 -3276 20450 4218 1003222 C ATOM 9194 CGl ILE C 246 -3340 23854 -8649 1005130 C ATOM 9279 CA SER C 258 -3185 19883 2875 1003222 C ATOM 9195 CDl ILE C 246 -2090 23475 -9428 1005130 C ATOM 9280 CB SER C 258 -3357 18377 2921 1003480 C ATOM 9196 C ILE C 246 -3684 20861 -6254 1005476 C ATOM 9281 OG SER C 258 -4689 18047 3277 1004492 C ATOM 9197 O ILE C 246 -4731 21030 -5617 1005476 C ATOM 9282 C SER C 258 -4293 20494 2029 1003222 C ATOM 9198 N THR C 247 -271420052 -5846 1004903 C ATOM 9283 O SER C 258 -5267 21029 2562 1003222 C ATOM 9199 CA THR C 247 -2848 19324 -4603 1004903 C ATOM 9284 N TYR C 259 ^■ 4154 20409 0715 1004887 C ATOM 9200 CB THR C 247 -3428 17930 -4859 1006584 C ATOM 9285 CA TYR C 259 -5150 20994 -0175 1004887 C ATOM 9201 OGl THR C 247 -3806 17340 -3615 1006308 C ATOM 9286 CB TYR C 259 -4775 22450 -0499 1004967 C ATOM 9202 CG2THRC247 -2401 17041 -5545 1006308 C ATOM 9287 CG TYR C 259 -3364 22584 -1018 1004542 C ATOM 9203 C THR C 247 -1479 19214 -3928 1004903 C ATOM 9288 CDl TYR C 259 -3056 22303 -2353 1004542 C 65251/C766

ATOM 9289 CEl TYR C 259 -1 744 22 304 -2 798 1 00 45 42 C ATOM 9374 CB ARG C 271 11 881 23 871 2 782 1 00 61 94 C ATOM 9290 CD2 TYR C 259 -2317 22 878 -0 152 1 0045 42 C ATOM 9375 CG ARG C 271 -11 246 23 434 -1 500 1 0055 06 C ATOM 9291 CE2 TYR C 259 -1 006 22 878 -0 592 1 0045 42 C ATOM 9376 CD ARG C 271 -11 324 24 547 -0454 1 0055 06 C ATOM 9292 CL TYR C 259 -0 726 22 587 -1 909 1 0045 42 C ATOM 9377 NE ARG C 271 -10 471 25 688 0 784 1 00 55 06 C ATOM 9293 OH TYR C 259 0 585 22 554 -2 313 1 00 45 42 C ATOM 9378 CZ ARG C 271 -10 914 26 861 -1 234 1 00 55 06 C ATOM 9294 C TYR C 259 -5 271 20 209 -1 462 1 0048 87 C ATOM 9379 NHl ARG C 271 -12 210 27064 -1 41" J 1 00 55 06 C ATOM 9295 O TYR C 259 -4397 19 410 -1 818 1 0048 87 C ATOM 9380 NH2 ARG C 271 10 060 27 842 -1 48 1 00 55 06 C ATOM 9296 N GLY C 260 -6370 20 455 -2 159 1 0045 95 C ATOM 9381 C ARG C 271 -12 525 21 495 -3 345 1 0063 18 C ATOM 9297 CA GLY C 260 -6 626 19 791 -3 419 1 00 45 95 C ATOM 9382 O ARG C 271 -13 727 21 382 -3 086 1 00 63 18 C ATOM 9298 C GLY C 260 -7 749 20 542 -4099 1 0045 95 C ATOM 9383 N TYR C 272 -11 663 20 492 -3 185 1 00 5025 C ATOM 9299 O GLY C 260 -8 910 20 451 -3 698 1 0045 95 C ATOM 9384 CA TYR C 272 -12 096 19 190 -2 680 1 00 5025 C ATOM 9300 N TYR C 261 -7406 21 316 -5 116 1 0049 08 C ATOM 9385 CB TYR C 272 -1 1 228 18 077 -3 260 1 00 68 10 C ATOM 9301 CA TYR C 261 -8 425 22 072 -5 821 1 00 49 08 C ATOM 9386 CG TYR C 272 -11 677 16 697 -2 831 1 00 65 57 C ATOM 9302 CB TYR C 261 -8 522 23 490 -5 254 1 00 77 59 C ATOM 9387 CDl TYR C 272 -12 74* 16 06C -3 462 1 00 65 57 C ATOM 9303 CG TYR C 261 -7256 24300 -5 379 1 00 61 38 C ATOM 9388 CEl TYR C 272 -13 183 14 799 -3 049 1 00 65 57 C ATOM 9304 CDl TYR C 261 -6 982 25 035 6 526 1 00 61 38 C ATOM 9389 CD2 TYR C 272 -11 05! 16 03" -1 773 1 00 65 57 C ATOM 9305 CEl TYR C 261 -5 824 25 799 -6 631 1 00 61 38 C ATOM 9390 CE2 TYR C 272 -11 486 14 777 -1 354 1 0065 57 C ATOM 9306 CD2 TYR C 261 -6 337 24 345 -4340 1 00 61 38 C ATOM 9391 CZ TYR C 272 -12 548 14 168 -1 999 1 00 65 57 C ATOM 9307 CE2 TYR C 261 -5 176 25 105 -4 431 1 00 61 38 C ATOM 9392 OH TYR C 272 -12 971 12 926 -1 606 1 00 65 57 C ATOM 9308 CZ TYR C 261 -4922 25 833 -5 575 1 00 61 38 C ATOM 9393 C TYR C 272 -12 040 19 102 1 155 00 5025 C ATOM 9309 OH TYR C 261 -3 778 26 604 -5 640 1 00 61 38 C ATOM 9394 O TYR C 272 10 979 19 281 -0 553 1 00 5025 C ATOM 9310 C TYR C 261 -8 161 22 106 -7321 1 0049 08 C ATOM 9395 N HIS C 273 13 173 1 8 817 -0 524 1 00 69 22 C ATOM 9311 O TYR C 261 -7 061 21 782 -7794 1 0049 08 C ATOM 9396 CA HIS C 273 -13 196 18 714 0929 0069 22 C ATOM 9312 N VAL C 262 -9 193 22 480 -8062 1 00 60 83 C ATOM 9397 CB HIS C 273 -14415 19 430 1 498 0011455 C ATOM 9313 CA VAL C 262 -9 108 22556 -9 506 1 00 60 83 C ATOM 9398 CO HIS C 273 -14282 20919 1 490 009528 C ATOM 9314 CB VAL C 262 -10222 21 727 -10 160 1 00 69 54 C ATOM 9399 CD2 HIS C 273 15 021 21 879 0 889 1 00 95 28 C ATOM 9315 CGl VAL C 262 -10291 22 024 -1 1 638 1 00 61 03 C ATOM 9400 NDl HIS C 273 -13 261 21 575 2 144 1 00 95 28 C ATOM 9316 CG2 VAL C 262 -9 968 20 254 -9 941 1 00 61 03 C ATOM 9401 CEl HIS C 273 -13 376 22 876 1 945 1 0095 28 C ATOM 9317 C VAL C 262 -9 277 23 998 -9943 1 00 60 83 C ATOM 9402 NE2 HIS C 273 -14436 23 087 1 186 1 0095 28 C ATOM 9318 O VAL C 262 -10278 24 635 -9 610 1 00 60 83 C ATOM 9403 C HIS C 273 • 13 159 17281 416 1 00 6922 C ATOM 9319 N GLU C 263 -8 298 24 524 -10 673 1 00 85 01 C ATOM 9404 O HIS C 273 14 027 1 6475 096 1 00 69 22 C ATOM 9320 CA GLU C 263 -8402 25 890 11 160 1 00 85 01 C ATOM 9405 N THR C 274 -12 122 16981 2 185 006223 C ATOM 9321 CB GLU C 263 -7 290 26785 -10 601 1 0010441 C ATOM 9406 CA THR C 274 -11 902 15 663 2 757 1 00 6223 C ATOM 9322 CG GLU C 263 -5 887 26280 -10 817 1 00 91 01 C ATOM 9407 CB THR C 274 -10 615 15 681 3 613 1 00 75 75 C ATOM 9323 CD GLU C 263 -4 842 27234 10257 I 00 91 01 C ATOM 9408 OGl THR C 274 -9 520 15 183 2 828 1 00 68 28 C ATOM 9324 OEI GLU C 263 -5 060 27 785 -9 149 1 00 91 01 C ATOM 9409 CG2 THR C 274 -1078( 14 866 4 889 1 00 68 28 C ATOM 9325 OE2 GLU C 263 -3 796 27421 -10 920 1 0091 01 C ATOM 9410 C THR C 274 -13 083 15 190 3 601 00 62 23 C ATOM 9326 C GLU C 263 -8 384 25 905 -12 677 1 00 85 01 C ATOM 9411 O THR C 274 -13 411 13 999 3 619 00 62 23 C ATOM 9327 O GLU C 263 -7942 24 955 -13330 1 00 8501 C ATOM 9412 N GLY C 275 -13 713 16 126 4 301 0060 19 C ATOM 9328 N THR C 264 -8 886 27 003 -13 220 1 00101 12 C ATOM 9413 CA GLY C 275 -14 851 15 783 5 131 1 00 60 19 C ATOM 9329 CA THR C 264 8991 27211 -14 650 1 00101 12 C ATOM 9414 C GLY C 275 -16 066 15 346 4334 00 60 19 C ATOM 9330 CB THR C 264 -10472 27464 -14 993 1 00 93 50 C ATOM 9415 O GLY C 275 -16492 14 200 4428 1 0060 19 C ATOM 9331 OGl THR C 264 11 051 26 252 -15 483 I 00 7243 C ATOM 9416 N ASP C 276 -16 613 6 253 3 535 1 00 66 63 C ATOM 9332 CG2 THR C 264 -10 636 28 567 -15 999 1 00 7243 C ATOM 9417 CA ASP C 276 -17795 15 980 2 721 1 0066 63 C ATOM 9333 C THR C 264 -8 130 28 399 -15047 1 00101 12 C ATOM 9418 CB ASP C 276 -18 323 17292 2 134 1 0017471 C ATOM 9334 O THR C 264 -7676 29 147 -14 189 1 00101 12 C ATOM 9419 CG ASP C 276 -18461 18381 3 178 1 00153 71 C ATOM 9335 N ALA C 265 -7 886 28 569 -16340 1 00 76 82 C ATOM 9420 ODl ASP C 276 -19 338 18 261 4 066 1 00153 71 C ATOM 9336 CA ALA C 265 -7 088 29 703 -16790 1 00 76 82 C ATOM 9421 OD2 ASP C 276 -17 680 19 356 3 114 1 00153 71 C ATOM 9337 CB ALA C 265 -6917 29 663 -18 310 1 00 58 52 C ATOM 9422 C ASP C 276 -17 562 4981 1 585 1 00 66 63 C ATOM 9338 C ALA C 265 -7 806 30 987 -16360 1 0076 82 C ATOM 9423 O ASP C 276 -18 518 14419 1 046 1 00 66 63 C ATOM 9339 O ALA C 265 -7 193 32 043 -16229 1 0076 82 C ATOM 9424 N LYS C 277 -16 300 14 761 1 223 00 70 79 C ATOM 9340 N ASN C 266 -9 108 30 877 -16 119 1 00 85 95 C ATOM 9425 CA LYS C 277 -15 949 13 849 0 139 1 0070 79 C ATOM 9341 CA ASN C 266 -9922 32015 -15 706 1 00 85 95 C ATOM 9426 CB LYS C 277 -16381 12429 0491 1 0010751 C ATOM 9342 CB ASN C 266 -11 373 31 819 -16 150 1 00165 17 C ATOM 9427 CG LYS C 277 -15 596 11 831 1 647 1 0092 72 C ATOM 9343 CG ASN C 266 -11 495 31 560 -17 637 1 0010702 C ATOM 9428 CD LYS C 277 -16270 10 572 2 176 1 00 92 72 C ATOM 9344 ODl ASN C 266 -10973 32 316 -18 454 1 00107 02 C ATOM 9429 CE LYS C 277 -15 466 9 902 3 286 00 92 72 C ATOM 9345 ND2 ASN C 266 12 191 30 487 -17 996 1 00107 02 C ATOM 9430 NZ LYS C 277 -14257 9 195 2 768 00 92 72 C ATOM 9346 C ASN C 266 -9 891 32 227 -14 199 1 00 85 95 C ATOM 9431 C LYS C 277 -16 596 14290 1 171 00 70 79 C ATOM 9347 O ASN C 266 -10330 33 266 -13 707 1 00 85 95 C ATOM 9432 O LYS C 277 -17 212 13 485 1 873 00 70 79 C ATOM 9348 N GLY C 267 9 386 31 238 -13467 1 00111 63 C ATOM 9433 N ARG C 278 -16442 15 575 -1 489 1 0069 75 C ATOM 9349 CA GLY C 267 -9 310 31 361 -12 021 1 00111 63 C ATOM 9434 CA ARG C 278 -17 000 16 169 -2 703 1 00 69 75 C ATOM 9350 C GLY C 267 -9 798 30 144 -11 260 1 00111 63 C ATOM 9435 CB ARG C 278 -18 505 16371 -2 535 1 00170 83 C ATOM 9351 O GLY C 267 -10 327 29 205 -11 858 1 00111 63 C ATOM 9436 CG ARG C 278 -18 838 17467 -1 555 1 00155 46 C ATOM 9352 N PRO C 268 -9 643 30 140 -9 926 1 00 81 13 C ATOM 9437 CD ARG C 278 -20 301 17474 1 198 1 00155 46 C ATOM 9353 CD PRO C 268 -9287 31 293 -9087 1 00 81 08 C ATOM 9438 NE ARG C 278 -20 626 18 600 -0 327 1 00155 46 C ATOM 9354 CA PRO C 268 -10 075 29 018 -9 091 1 00 81 13 C ATOM 9439 CZ ARG C 278 -21 738 18 688 0 395 1 00155 46 C ATOM 9355 CB PRO C 268 -9945 29 571 -7671 1 009697 C ATOM 9440 NHl ARG C 278 22 634 1770 ) 0352 1 0015546 C ATOM 9356 CG PRO C 268 -10 114 31 036 -7 857 1 00 81 08 C ATOM 9441 NH2 ARG C 27S -21 967 19 764 1 138 1 00155 46 C ATOM 9357 C PRO C 268 -11 488 28 550 -9414 1 00 81 13 C ATOM 9442 C ARG C 278 -16 326 17 526 -2 945 1 00 69 75 C ATOM 9358 O PRO C 268 -12 398 29 357 -9 589 1 00 81 13 C ATOM 9443 O ARG C 278 -15 618 18 039 -2 081 1 00 69 75 C ATOM 9359 N LEU C 269 -11 657 27 234 -9477 1 00 64 68 C ATOM 9444 N PHE C 279 -16 535 18 103 4 120 00 59 88 C ATOM 9360 CA LEU C 269 -12 941 26636 -9 796 1 00 64 68 C ATOM 9445 CA PHE C 279 -15 958 19 404 -4420 1 00 59 88 C ATOM 9361 CB LEU C 269 -12755 25 662 -10 959 1 00 97 46 C ATOM 9446 CB PHE C 279 -15 695 19 567 -5 911 1 0064 92 C ATOM 9362 CG LEU C 269 -14013 25228 -11 696 1 00 62 80 C ATOM 9447 CG PHE C 279 -14453 18 893 -6385 1 004869 C ATOM 9363 CDl LEU C 269 -14 790 26459 -12 142 1 00 62 80 C ATOM 9448 CDl PHE C 279 -14485 17 591 -6 857 1 00 48 69 C ATOM 9364 CD2 LEU C 269 13 621 24 357 12 884 1 0062 80 C ATOM 9449 CD2 PHE C 279 -13 244 19 562 -6 365 1 0048 69 C ATOM 9365 C LEU C 269 -13 582 25 925 -8 603 1 00 64 68 C ATOM 9450 CEl PHE C 279 -13 320 16959 -7 310 1 0048 69 C ATOM 9366 O LEU C 269 -14 549 26 426 -8 024 1 00 64 68 C ATOM 9451 CE2 PHE C 279 -12 076 18 944 -6 811 1 0048 69 C ATOM 9367 N ALA C 270 13 039 24 767 -8231 1 0063 31 C ATOM 9452 CZ PHE C 279 -12 114 17 637 -7285 1 0048 69 C ATOM 9368 CA ALA C 270 -13 577 23 990 -7 113 1 00 63 31 C ATOM 9453 C PHE C 279 -16 898 20 512 - 3 981 1 00 59 88 C ATOM 9369 CB ALA C 270 -14492 22885 -7637 1 00 83 13 C ATOM 9454 O PHE C 279 -18 121 20320 3 902 005988 C ATOM 9370 C ALA C 270 -12 511 23 382 -6205 1 0063 31 C ATOM 9455 N THR C 280 -16 324 21 677 -3 697 00 59 07 C ATOM 9371 O ALA C 270 -11 445 22 948 -6 655 1 00 63 31 C ATOM 9456 CA THR C 280 -17 110 22 830 -3 289 1 005907 C ATOM 9372 N ARG C 271 -12 841 23 337 -4921 1 0063 18 C ATOM 9457 CB THR C 280 -16990 23 087 -1 796 1 00 7948 C ATOM 9373 CA ARG C 271 -11 964 22 818 -3 885 1 00 63 18 C ATOM 9458 OGl THR C 280 -17 24! i 21 872 -1 086 1 00 60 00 C 65251/C766

ATOM 9459 CG2THRC2S0 -17995 24143 -1370 1006000 C ATOM 9544 CA GLY C 291 -16012 15344-15700 1007593 C ATOM 9460 C THR C 280 -16623 24068 -4029 1005907 C ATOM 9545 C GLY C 291 -15665 14877-14298 1007593 C ATOM 9461 O THR C 280 -1542024257 -4216 1005907 C ATOM 9546 O GLY C 291 -16489 14286-13601 1007593 C ATOM 9462 N LYS C 281 -17566 24899 -4458 1006232 C ATOM 9547 N MET C 292 -14431 15143-13884 1007526 C ATOM 9463 CA LYS C 281 -17251 26130 -5172 1006232 C ATOM 9548 CA MET C 292 -13941 14748-12565 1007526 C ATOM 9464 CB LYS C 281 18530 26952 -5349 10011069 C ATOM 9549 CB MET C 292 -12444 14975-12492 1009177 C ATOM 9465 CG LYS C 281 -19471 26863 -4145 1008663 C ATOM 9550 CG MET C 292 -12110 16455-12492 1009177 C ATOM 9466 CD LYS C 281 -19942 28232 -3660 1008663 C ATOM 9551 SD MET C 292 -10434 16803-11939 1009177 C ATOM 9467 CE LYS C 281 -20809 28946 -4685 1008663 C ATOM 9552 CE MET C 292 -9726 17466-13413 1009177 C ATOM 9468 NZ LYS C 281 -21313 30251 -4166 1008663 C ATOM 9553 C MET C 292 -14583 15548 11433 1007526 C ATOM 9469 C LYS C 281 -16207 26966 -4425 1006232 C ATOM 9554 O MET C 292 -14269 15337-10267 1007526 C ATOM 9470 O LYS C 281 -16224 27050 -3195 1006232 C ATOM 9555 N LEU C 293 -15475 16468-11767 1007228 C ATOM 9471 N MET C 282 -15289 27572 -5171 1007111 C ATOM 9556 CA LEU C 293 -16096 17294-10744 1007228 C ATOM 9472 CA MET C 282 -14269 28427 -4578 1007111 C ATOM 9557 CB LEU C 293 -16230 18730-11262 1007911 C ATOM 9473 CB MET C 282 -1289628138 -5170 1006776 C ATOM 9558 CG LEU C 293 -14910 19444-11555 1007911 C ATOM 9474 CG MET C 282 -12308 26821 ^l 773 1006776 C ATOM 9559 CDl LEU C 293 1516620802-12201 1007911 C ATOM 9475 SD MET C 282 -10546 26795 -5136 1006776 C ATOM 9560 CD2 LEU C 293 -14149 19599-10255 1007911 C ATOM 9476 CE MET C 282 -10535 26107 -6783 1006776 C ATOM 9561 C LEU C 293 -17438 16835-10183 1007228 C ATOM 9477 C MET C 282 -14624 29877 -4868 1007111 C ATOM 9562 O LEU C 293 -17957 17469 -9270 1007228 C ATOM 9478 O MET C 282 -14005 30792 -4330 1007111 C ATOM 9563 N THR C 294 -18012 15756-10708 1008844 C ATOM 9479 N THR C 283 -15623 30071 -5726 1009259 C ATOM 9564 CA THR C 294 -19301 15291 -10188 1008844 C ATOM 9480 CA THR C 283 16084 31395 6131 1009259 C ATOM 9565 CB THR C 294 -20441 15386-11217 10010622 C ATOM 9481 CB THR C 283 15625 31718 -7571 1008053 C ATOM 9566 OGl THR C 294 -20321 16599-11963 I 0010622 ATOM 9482 OGl THR C 283 -1419631779 -7619 1008053 C C ATOM 9483 CG2THRC283 16192 33043 -8035 1008053 C ATOM 9567 CG2 THR C 294 -21790 15374 -10502 10010622 ATOM 9484 C THR C 283 -17605 31413 6100 1009259 C C ATOM 9485 O THR C 283 -18236 30359 -6149 1009259 C ATOM 9568 C THR C 294 -19261 13847 -9759 1008844 C ATOM 9486 N HIS C 284 -18187 32608 -6010 1008639 C ATOM 9569 O THR C 294 -18496 13043-10289 1008844 C ATOM 9487 CA HIS C 284 -19644 32764 -5994 1008639 C ATOM 9570 N VAL C 295 -20110 13520 8799 1008562 C ATOM 9488 CB HIS C 284 -2000834251 -5914 10016330 C ATOM 9571 CA VAL C 295 -20196 12156 -8316 1008562 C ATOM 9489 CG HIS C 284 -19408 35076 -7012 10016330 C ATOM 9572 CB VAL C 295 -21076 1208S -7060 10010414 C ATOM 9490 CD2 HIS C 284 -19983 35767 -8026 10016330 C ATOM 9573 CGl VAL C 295 21087 10665 6504 10010414 C ATOM 9491 NDl HIS C 284 -1804735236 -7166 10016330 C ATOM 9574 CG2 VAL C 295 -20563 13087 6024 10010414 C ATOM 9492 CEl HIS C 284 -17809 35987 -8227 10016330 C ATOM 9575 C VAL C 295 -20812 11302 -9426 1008562 C ATOM 9493 NE2HISC284 -1896736322 -8766 10016330 C ATOM 9576 O VAL C 295 20655 10080 9447 1008562 C ATOM 9494 C HIS C 284 -2020732167 -7287 1008639 C ATOM 9577 N LYS C 296 -21504 11969-10348 1009207 C ATOM 9495 O HIS C 284 -21284 31569 -7303 1008639 C ATOM 9578 CA LYS C 296 -22156 11314-11476 1009207 C ATOM 9496 N LYS C 285 -1943732331 -8360 10011069 C ATOM 9579 CB LYS C 296 -22863 12353-12351 1009569 C ATOM 9497 CA LYS C 285 -1978731855 -9693 10011069 C ATOM 9580 CG LYS C 296 -23928 13170-11636 1009569 C ATOM 9498 CB LYS C 285 -18593 32054-10635 10010597 C ATOM 9581 CD LYS C 296 -25183 12360-11369 1009569 C ATOM 9499 CG LYS C 285 -18926 32774-11931 10010597 C ATOM 9582 CE LYS C 296 -25900 12021 -12666 1009569 C ATOM 9500 CD LYS C 285 -19374 34212-11671 10010597 C ATOM 9583 NZ LYS C 296 -27130 11181 -12495 1009569 C ATOM 9501 CE LYS C 285 -19695 34946-12972 10010597 C ATOM 9584 C LYS C 296 -21152 10548-12332 1009207 C ATOM 9502 NZ LYS C 285 -20113 36355 12736 10010597 C ATOM 9585 O LYS C 296 -21485 9511 -12913 1009207 C ATOM 9503 C LYS C 285 -20230 30396 -9760 10011069 C ATOM 9586 N ASN C 297 -19925 11059-12401 1006489 C ATOM 9504 O LYS C 285 -2104930036-10604 10011069 C ATOM 9587 CA ASN C 297 -18874 10442-13207 1006489 C ATOM 9505 N GLY C 286 -1969029562 -8876 1007706 C ATOM 9588 CB ASN C 297 -17606 11302-13183 1007586 C ATOM 9506 CA GLY C 286 -20029 28146 -8880 1007706 C ATOM 9589 CG ASN C 297 -16571 10856-14211 1007586 C ATOM 9507 C GLY C 286 -19145 27400 -9865 1007706 C ATOM 9590 ODl ASN C 297 -16055 9740-14155 1007586 C ATOM 9508 O GLY C 286 -1824727993-10466 1007706 C ATOM 9591 ND2ASNC297 -16266 11734-15158 1007586 C ATOM 9509 N PHE C 287 -19377 26104-10035 1008365 C ATOM 9592 C ASN C 297 -18526 9015-12793 1006489 C ATOM 9510 CA PHE C 287 -1857725323-10974 1008365 C ATOM 9593 O ASN C 297 -18387 8695-11612 1006489 C ATOM 9511 CB PHE C 287 -17403 24644-10255 1006785 C ATOM 9594 N THR C 298 -18383 8160-13793 1006802 C ATOM 9512 CG PHE C 287 -1781423552 -9307 1006785 C ATOM 9595 CA THR C 298 -18053 6766 13581 1006802 C ATOM 9513 CDl PHE C 287 -18013 22249 -9765 1006785 C ATOM 9596 CB THR C 298 -18040 6023-14935 10012022 C ATOM 9514 CD2PHEC287 -18009 23826 -7951 1006785 C ATOM 9597 OGl THR C 298 -17297 4808-14809 10012022 C ATOM 9515 CEl PHE C 287 -18403 21226 -8885 1006785 C ATOM 9598 CG2THRC298 -17420 6892-16020 10012022 C ATOM 9516 CE2FHEC287 -18397 22818 -7059 1006785 C ATOM 9599 C THR C 298 -16713 6546-12854 1006802 C ATOM 9517 CZ PHE C 287 -1859421513 -7528 1006785 C ATOM 9600 O THR C 298 -16520 5524-12192 1006802 C ATOM 9518 C PHEC 287 -19434 24279-11673 1008365 C ATOM 9601 N LEU C 299 -15794 7502-12961 1006519 C ATOM 9519 O PHE C 287 -20327 23688 -11062 1008365 C ATOM 9602 CA LEU C 299 -14489 7369-12313 1006519 C ATOM 9520 N PRO C 288 -19176 24042-12973 1008371 C ATOM 9603 CB LEU C 299 -13392 7871-13244 1006529 C ATOM 9521 CD PRO C 288 -18098 24648-13777 1008347 C ATOM 9604 CG LEU C 299 -13211 7041-14503 1006529 C ATOM 9522 CA PRO C 288 -19926 23063-13768 1008371 C ATOM 9605 CDl LEU C 299 -12201 7708-15405 1006529 C ATOM 9523 CB PRO C 288 -19393 23289-15178 1008347 C ATOM 9606 CD2LEUC299 -12761 5653-14125 1006529 C ATOM 9524 CG PRO C 288 17971 23676-14931 1008347 C ATOM 9607 C LEU C 299 -14378 8093-10969 1006519 C ATOM 9525 C PRO C 288 -19713 21629-13291 1008371 C ATOM 9608 O LEU C 299 -13299 8151 -10370 1006519 C ATOM 9526 O PRO C 288 -18583 21141 -13234 1008371 C ATOM 9609 N TRP C 300 -15494 8642-10499 1005107 C ATOM 9527 N LYS C 289 -20805 20955 -12947 1008375 C ATOM 9610 CA TRP C 300 -15516 9351 -9235 1005107 C ATOM 9528 CA LYS C 289 -20713 19583-12477 1008375 C ATOM 9611 CB TRP C 300 -16954 9632 -8808 1007513 C ATOM 9529 CB LYS C 289 -21943 19232-11629 10011554 C ATOM 9612 CG TRP C 300 -17032 10398 -7541 1007513 C ATOM 9530 CG LYS C 289 -21865 19818-10222 10011554 C ATOM 9613 CD2TRPC300 -16494 11702 -7297 1007513 C ATOM 9531 CD LYS C 289 -23080 19479 -9389 10011554 C ATOM 9614 CE2TRPC300 -16813 12041 -5966 1007513 C ATOM 9532 CE LYS C 289 -24301 20231 -9886 10011554 C ATOM 9615 CE3TRPC300 -15773 12620 -8075 1007513 C ATOM 9533 NZ LYS C 289 -25513 19938 -9067 10011554 C ATOM 9616 CDl TRP C 300 -17633 10007 -6387 1007513 C ATOM 9534 C LYS C 289 -20545 18619-13639 1008375 C ATOM 9617 NEl TRP C 300 -17508 10987 -5434 1007513 C ATOM 9535 O LYS C 289 -21493 17955-14061 1008375 C ATOM 9618 CZ2TRPC300 -16438 13264 -5390 1007513 C ATOM 9536 N VAL C 290 -19314 18551 -14140 1007324 C ATOM 9619 CZ3TRPC300 -15398 13836 -7505 1007513 C ATOM 9537 CA VAL C 290 -18969 17690-15265 1007324 C ATOM 9620 CH2 TRP C 300 -15733 14146 -6174 1007513 C ATOM 9538 CB VAL C 290 -18854 18516-16567 1009618 C ATOM 9621 C TRP C 300 -14813 8577 -8133 1005107 C ATOM 9539 CGl VAL C 290 -20108 19350-16769 1009618 C ATOM 9622 O TRP C 300 -14060 9156 -7359 1005107 C ATOM 9540 CG2VALC290 17624 19419-16504 1009618 C ATOM 9623 N LYS C 301 -15054 7273 -8058 1007580 C ATOM 9541 C VAL C 290 -17625 17013-15008 1007324 C ATOM 9624 CA LYS C 301 -14431 6464 -7018 1007580 C ATOM 9542 O VAL C 290 -16914 17372-14076 1007324 C ATOM 9625 CB LYS C 301 -14849 4995 -7142 1009696 C ATOM 9543 N GLY C 291 -17281 16040-15843 1007593 C ATOM 9626 CG LYS C 301 -16359 4775 -7029 1009696 C 65251/C766

ATOM 9627 CD LYS C 301 -16956 5497 -5814 1009696 C ATOM 9712 CG TYR C 312 -7883 11503 4928 1004731 C ATOM 962S CE LYS C 301 -18474 5631 -5927 1009696 C ATOM 9713 CDl TYR C 312 -8802 12281 5632 1004731 C ATOM 9629 NZ LYS C 301 -19037 6650 -4991 I 009696 C ATOM 9714 CEl TYR C 312 -9207 11931 6926 1004731 C ATOM 9630 C LYS C 301 -12914 6586 -7046 10075S0 C ATOM 9715 CD2 TYR C 312 -7379 10359 5549 1004731 C ATOM 9631 O LYS C 301 -12265 6593 -5997 1007580 C ATOM 9716 CE2 TYR C 312 -7775 9998 6842 1004731 C ATOM 9632 N ASP C 302 12342 6692 -8240 1007007 C ATOM 9717 CZ TYR C 312 -8687 10786 7523 1004731 C ATOM 9633 CA ASP C 302 -10892 6832 -8354 1007007 C ATOM 9718 OH TYR C 312 -9070 10443 8801 1004731 C ATOM 9634 CB ASP C 302 -10439 6565 -9789 1009543 C ATOM 9719 C TYR C 312 -5270 12746 4484 1004709 C ATOM 9635 CG ASP C 302 -10535 5106-10159 1009543 C ATOM 9720 O TYR C 312 -5272 13019 5676 1004709 C ATOM 9636 ODl ASP C 302 -10015 4276 -9383 1009543 C ATOM 9721 N MET C 313 -4257 12118 3904 1004218 C ATOM 9637 OD2 ASP C 302 -11 119 4789-11221 1009543 C ATOM 9722 CA MET C 313 -3113 11727 4697 1004218 C ATOM 9638 C ASP C 302 -10448 8228 -7914 1007007 C ATOM 9723 CB MET C 313 -3483 10525 5554 1007215 C ATOM 9639 O ASP C 302 -9380 8391 -7318 1007007 ATOM 9724 CG MET C 313 -2370 10061 6459 1007200 C ATOM 9640 N VAL C 303 -11270 9233 8214 1005506 C ATOM 9725 SD MET C 313 -2807 8576 7352 1007200 C ATOM 9641 CA VAL C 303 -10963 10600 -7817 1005506 C ATOM 9726 CE MET C 313 -4305 9121 8174 1007200 C ATOM 9642 CB VAL C 303 -12045 11583 -8294 1006887 C ATOM 9727 C MET C 313 1881 U 393 3869 1004218 C ATOM 9643 CGl VAL C 303 -11784 12962 -7731 1005818 C ATOM 9728 O MET C 313 -0747 11 636 4302 1004218 C ATOM 9644 CG2 VAL C 303 -12053 11637 -9806 1005818 C ATOM 9729 N GLY C 314 -2096 10830 2683 1004728 C ATOM 9645 C VAL C 303 -10883 10635 6297 1005506 C ATOM 9730 CA GLY C 314 -0977 10453 1 835 1004728 C ATOM 9646 O VAL C 303 -9882 11083 -5743 1005506 C ATOM 9731 C GLY C 314 0124 11489 1718 1004728 C ATOM 9647 N LYS C 304 -11931 10148 -5631 1006786 C ATOM 9732 O GLY C 314 1301 11 199 1945 1004728 C ATOM 9648 CA LYS C 304 -11972 10102 4167 1006786 C ATOM 9733 N CYS C 315 -0265 12707 1370 1005388 C ATOM 9649 CB LYS C 304 -13170 9292 -3681 1009269 C ATOM 9734 CA CYS C 315 0694 13777 1207 1005388 C ATOM 9650 CG LYS C 304 -14472 10042 -3593 1007461 C ATOM 9735 CB CYS C 315 -0019 15040 0738 1007248 C ATOM 9651 CD LYS C 304 15566 9100 -3 117 1007461 C ATOM 9736 SG CYS C 315 1 109 16278 0092 1007785 C ATOM 9652 CE LYS C 304 -16891 9824 -2913 1007461 C ATOM 9737 C CYS C 315 1498 14072 2475 1005388 C ATOM 9653 NZ LYS C 304 -18005 8888 -2595 1007461 C ATOM 9738 O CYS C 315 2734 14085 2444 1005388 C ATOM 9654 C LYS C 304 -10716 9456 -3602 1006786 C ATOM 9739 N SER C 316 0805 14304 3587 1005313 C ATOM 9655 O LYS C 304 -10116 9958 -2652 1006786 C ATOM 9740 CA SER C 316 1483 14604 4847 1005313 C ATOM 9656 N ALA C 305 -10329 8333 -4194 1006511 C ATOM 9741 CB SER C 316 0469 14754 5971 1004610 C ATOM 9657 CA ALA C 305 -9155 7594 -3748 1006511 C ATOM 9742 OG SER C 316 -0116 13500 6272 1005160 C ATOM 9658 CB ALA C 305 9174 6191 -4358 1003736 C ATOM 9743 C SER C 316 2506 13535 5242 1005313 C ATOM 9659 C ALA C 305 -7812 8275 -4034 1 006511 C ATOM 9744 O SER C 316 3458 13821 5966 1005313 C ATOM 9660 O ALA C 305 -6983 8410 -3141 1 0065 11 C ATOM 9745 N LEU C 317 2303 12301 4791 1005252 C ATOM 9661 N TYR C 306 -7592 8702 -5271 1005100 C ATOM 9746 CA LEU C 317 3246 11233 5094 1005252 C ATOM 9662 CA TYR C 306 -6328 9344 -5629 1005100 C ATOM 9747 CB LEU C 317 2562 9869 4987 1006026 C ATOM 9663 CB TYR C 306 -6177 9401 -7144 1008358 C ATOM 9748 CG LEU C 317 1558 9534 6092 1005277 C ATOM 9664 CG TYR C 306 6017 8046 -7779 1007827 C ATOM 9749 CDl LEU C 317 0845 8231 5776 1005277 C ATOM 9665 CDl TYR C 306 -6468 7807 -9074 1007827 C ATOM 9750 CD2 LEU C 317 2290 9434 7416 1005277 C ATOM 9666 CEl TYR C 306 -6328 6558 -9661 1007827 C ATOM 9751 C LEU C 317 4408 11297 4115 1005252 C ATOM 9667 CD2 TYR C 306 -5416 7000 -7087 1007827 C ATOM 9752 O LEU C 317 5573 11 172 4497 1005252 C ATOM 9668 CE2 TYR C 306 -5271 5755 -7665 1007827 C ATOM 9753 N ALA C 318 4080 11503 2846 1006076 C ATOM 9669 CZ TYR C 306 -5728 5538 -8950 1007827 C ATOM 9754 CA ALA C 318 5084 11572 1804 1006076 C ATOM 9670 OH TYR C 306 5578 4301 9527 1007827 C ATOM 9755 CB ALA C 318 4405 11706 0462 1004238 C ATOM 9671 C TYR C 306 -6162 10738 -5070 1005100 C ATOM 9756 C ALA C 318 6067 12717 2002 1006076 C ATOM 9672 O TYR C 306 -5127 11041 Jl 491 1005100 C ATOM 9757 O ALA C 318 7282 12527 1893 1006076 C ATOM 9673 N LEU C 307 -7173 11585 -5256 10048^5 C ATOM 9758 N ILE C 319 5544 13905 2297 1005241 C ATOM 9674 CA LEU C 307 -7118 12958 4767 1004875 C ATOM 9759 CA ILE C 319 6400 15072 2465 1005241 C ATOM 9675 CB LEU C 307 -8055 13853 -5580 1007128 C ATOM 9760 CB ILE C 319 5610 16285 2992 1006959 C ATOM 9676 CG LEU C 307 -8211 15291 -5070 1003941 C ATOM 9761 CG2 ILE C 319 5252 16078 4439 1004415 C ATOM 9677 CDl LEU C 307 -6864 16014 -5066 1003941 C ATOM 9762 CGl ILE C 319 6459 17548 2854 1004415 C ATOM 9678 CD2 LEU C 307 -9216 16022 -5945 1003941 C ATOM 9763 CDl ILE C 319 5736 18838 3205 I 004415 C ATOM 9679 C LEU C 307 -7477 13050 -3288 1004875 C ATOM 9764 C ILE C 319 7577 14798 3390 1005241 C ATOM 9680 O LEU C 307 -6723 13617 -2491 I 004875 C ATOM 9765 O ILE C 319 8641 15388 3230 1005241 C ATOM 9681 N GLY C 308 -8627 12493 -2926 1006544 C ATOM 9766 N LEU C 320 7398 13897 4350 1006298 C ATOM 9682 CA GLY C 308 -9052 12522 -1539 1006544 C ATOM 9767 CA LEU C 320 8475 13573 5278 1006298 C ATOM 9683 C GLY C 308 -8048 11857 -0611 1006544 C ATOM 9768 CB LEU C 320 7922 12823 6490 1007520 C ATOM 9684 O GLY C 308 -7702 12401 0433 1006544 C ATOM 9769 CG LEU C 320 6975 13641 7373 1005304 C ATOM 9685 N GLY C 309 -7574 10678 -0989 1005747 C ATOM 9770 CDl LEU C 320 6545 12804 8557 1005304 C ATOM 9686 CA GLY C 309 -6622 9972 -0153 1005747 C ATOM 9771 CD2 LEU C 320 7664 14919 7846 1005304 C ATOM 9687 C GLY C 309 -5341 10742 0095 1005747 C ATOM 9772 C LEU C 320 9599 12768 4615 1006298 C ATOM 9688 O GLY C 309 -4877 10867 1236 1005747 C ATOM 9773 O LEU C 320 10765 12885 5000 1006298 C ATOM 9689 N PHE C 310 -4763 11257 -0984 1005355 C ATOM 9774 N ASP C 321 9256 11955 3620 1007104 C ATOM 9690 CA PHE C 310 -3523 12012 -0906 1005355 C ATOM 9775 CA ASP C 321 10264 11 167 2913 1007104 C ATOM 9691 CB PHE C 310 -3140 12494 -2306 1004757 C ATOM 9776 CB ASP C 321 9610 10084 2049 10011233 C ATOM 9692 CG PHE C 310 1755 13070 2398 1004340 C ATOM 9777 CG ASP C 321 8998 8964 2875 1009133 C ATOM 9693 CDl PHE C 310 -0648 12286 -2122 1004340 C ATOM 9778 ODl ASP C 321 9659 8506 3831 1009133 C ATOM 9694 CD2 PHE C 310 -1562 14399 -2784 1004340 C ATOM 9779 OD2 ASP C 321 7866 8533 2560 1009133 C ATOM 9695 CEl PHE C 310 0633 12810 -2230 1004340 C ATOM 9780 C ASP C 321 11096 12093 2037 1007104 C ATOM 9696 CE2 PHE C 310 0287 14933 -2895 1004340 C ATOM 9781 O ASP C 321 12307 11915 1921 1007104 C ATOM 9697 CZ PHE C 310 0815 14135 -2617 1004340 C ATOM 9782 N TYR C 322 10446 13079 1421 1006939 C ATOM 9698 C PHE C 310 -3710 13202 0028 1005355 C ATOM 9783 CA TYR C 322 11 155 14038 0579 1006939 C ATOM 9699 O PHE C 310 -2870 13477 0889 1005355 C ATOM 9784 CB TYR C 322 10199 15066 -0029 1006889 C ATOM 9700 N GLU C 311 -4828 13896 -0151 1004424 C ATOM 9785 CG TYR C 322 9352 14563 -1 174 1005960 C ATOM 9701 CA GLU C 311 -5144 15069 0642 1004424 C ATOM 9786 CDl TYR C 322 8301 13680 -0953 1005960 C ATOM 9702 CB GLU C 311 -6325 15817 0032 1008530 C ATOM 9787 CEl TYR C 322 7489 13249 -2005 1005960 C ATOM 9703 CG GLU C 311 -6373 17268 0438 1006953 C ATOM 9788 CD2 TYR C 322 9580 15002 -2479 1005960 C ATOM 9704 CD GLU C 311 -7626 17977 -0030 1006953 C ATOM 9789 CE2 TYR C 322 8775 14577 -3534 1005960 C ATOM 9705 OEl GLU C 311 -8087 17704 -1 155 1006953 C ATOM 9790 CZ TYR C 322 7729 13701 -3287 1005960 C ATOM 9706 OE2 GLU C 311 -8141 18825 0725 1006953 C ATOM 9791 OH TYR C 322 6906 13286 -4310 1005960 C ATOM 9707 C GLU C 311 -5474 14703 2080 1004424 C ATOM 9792 C TYR C 322 12167 14778 1437 1006939 C ATOM 9708 O GLU C 311 -5176 15450 3001 1004424 C ATOM 9793 O TYR C 322 13328 14918 1064 1006939 C ATOM 9709 N TYR C 312 -6093 13548 2276 1004709 C ATOM 9794 N GLN C 323 11711 15250 2591 1005976 C ATOM 9710 CA TYR C 312 -6459 13115 3613 1004709 C ATOM 9795 CA GLN C 323 12564 15980 3504 1005976 C ATOM 9711 CB TYR C 312 -7407 11917 3557 1005261 C ATOM 9796 CB GLN C 323 11812 16295 4785 1008866 C 65251/C766

ATOM 9797 CG GLN C 323 12 642 17 050 5 775 1 00 63 05 C ATOM 9882 OGl THR C 334 19342 30762 4918 1008412 C ATOM 9798 CD GLN C 323 11 851 17 461 6 995 1 00 63 05 C ATOM 9883 CG2 THR C 334 18306 32814 5667 1008412 C ATOM 9799 OEl GLN C 323 11 186 16640 7 620 1 006305 C ATOM 9884 C THR C 334 16645 31392 7441 1007534 C ATOM 9800 NE2 GLN C 323 11 924 18 738 7 346 1 0063 05 C ATOM 9885 O THR C 334 15543 31591 6930 1007270 C ATOM 9801 C GLN C 323 13 827 15 201 3 821 1 00 59 76 C ATOM 9886 N THR C 335 16992 31849 8638 1005232 C ATOM 9802 O GLN C 323 14920 15 762 3 791 1 00 59 76 C ATOM 9887 CA THR C 335 16076 32632 9458 10052 Il C ATOM 9803 N LYS C 324 13 685 13 913 4 121 1 00 63 12 C ATOM 9888 CB THR C 335 16523 32648 10898 1005942 C ATOM 9804 CA LYS C 324 14 840 13 073 4 429 1 00 63 12 C ATOM 9889 OGl THR C 335 16858 31 315 11302 1004878 C ATOM 9805 CB LYS C 324 14413 11 631 4 702 1 00100 10 C ATOM 9890 CG2 THR C 335 15406 33168 11769 1004878 C ATOM 9806 CG LYS C 324 13 835 11 383 6 066 1 00 89 53 C ATOM 9891 C THR C 335 15934 34072 8992 1005297 C ATOM 9807 CD LYS C 324 13 711 9 887 6 314 1 00 89 53 C ATOM 9892 O THR C 335 16918 34768 8771 1005432 C ATOM 9808 CE LYS C 324 13 166 9 595 7 711 1 00 89 53 C ATOM 9893 N PRO C 336 14695 34548 8871 1004992 C ATOM 9809 NZ LYS C 324 13 169 8 139 8045 1 00 89 53 C ATOM 9894 CD PRO C 336 13422 33860 9149 1004564 C ATOM 9810 C LYS C 324 15 859 13 049 3 295 1 0063 12 C ATOM 9895 CA PRO C 336 14446 35909 8418 1004950 C ATOM 9811 O LYS C 324 17050 13 270 3 502 1 0063 12 C ATOM 9896 CB PRO C 336 13019 35820 7907 1005450 C ATOM 9812 N MET C 325 15 388 12 767 2 091 1 00 75 86 C ATOM 9897 CG PRO C 336 12397 34974 8971 1004564 C ATOM 9813 CA MET C 325 16 281 12 693 0948 1 0075 86 C ATOM 9898 C PRO C 336 14585 36968 9493 1004954 C ATOM 9814 CB MET C 325 15 587 11 967 -0201 1 00 91 27 C ATOM 9899 O PRO C 336 14781 36662 10666 1005017 C ATOM 9815 CG MET C 325 15 281 10 527 0 113 1 00 79 83 C ATOM 9900 N THR C 337 14467 38215 9048 1006501 C ATOM 9816 SD MET C 325 14464 9 691 -1 238 1 00 79 83 C ATOM 9901 CA THR C 337 14527 39400 9886 1006847 C ATOM 9817 CE MET C 325 12 784 9 830 -0 746 1 00 79 83 C ATOM 9902 CB THR C 337 15537 40405 9333 10011414 C ATOM 9818 C MET C 325 16783 14043 0470 1 0075 86 C ATOM 9903 OGl THR C 337 16860 39915 9564 1006503 C ATOM 9819 O MET C 325 17 732 14 117 -0 308 1 00 75 86 C ATOM 9904 CG2 THR C 337 15365 41755 9989 1006503 C ATOM 9820 N ALA C 326 16 156 15 113 0 932 1 0058 65 C ATOM 9905 C THR C 337 13137 39987 9761 1007604 C ATOM 9821 CA ALA C 326 16 573 16436 0 506 1 00 58 65 C ATOM 9906 O THR C 337 12628 40134 8654 1006742 C ATOM 9822 CB ALA C 326 15 350 17 348 0 362 1 00 60 09 C ATOM 9907 N VAL C 338 12513 40310 10882 1004745 C ATOM 9823 C ALA C 326 17 580 17 050 1 470 1 0058 65 C ATOM 9908 CA VAL C 338 II 170 40874 10824 1005431 C ATOM 9824 O ALA C 326 18402 17866 1 067 1 005865 C ATOM 9909 CB VAL C 338 10147 39969 11542 1004227 C ATOM 9825 N LYS C 327 17 529 16 630 2 729 1 00129 75 C ATOM 9910 CGl VAL C 338 8731 40444 11249 10041 89 C ATOM 9826 CA LYS C 327 18 398 17 169 3 768 1 00129 75 C ATOM 9911 CG2 VAL C 338 10330 38535 11094 1004189 C ATOM 9827 CB LYS C 327 18 803 16086 4 763 1 00157 86 C ATOM 9912 C VAL C 338 11098 42264 11430 1005878 C ATOM 9828 CG LYS C 327 19 442 16 675 6 012 1 00 76 15 C ATOM 9913 O VAL C 338 11814 42576 12379 1005861 C ATOM 9829 CD LYS C 327 19 723 15 618 7 062 1 00 76 15 C ATOM 9914 N LYS C 339 10225 43090 10859 1005926 C ATOM 9830 CE LYS C 327 20225 16247 8 360 1 0076 15 C ATOM 9915 CA LYS C 339 10012 44459 11307 1005714 C ATOM 9831 NZ LYS C 327 20 527 15 223 9 410 1 00 76 15 C ATOM 9916 CB LYS C 339 11005 45400 10617 100161 77 C ATOM 9832 C LYS C 327 19 651 17 890 3 297 1 0012975 C ATOM 9917 CG LYS C 339 12454 45136 10992 10013008 C ATOM 9833 O LYS C 327 19 771 19 103 3 469 1 00129 75 C ATOM 9918 CD LYS C 339 13414 45447 9849 10013008 C ATOM 9834 N GLY C 328 20 582 17 162 2 695 1 00 73 50 C ATOM 9919 CE LYS C 339 14837 45019 10200 10013008 C ATOM 9835 CA GLY C 328 21 804 17 816 2 261 1 00 73 50 C ATOM 9920 NZ LYS C 339 15760 45103 9035 10013008 C ATOM 9836 C GLY C 328 21 846 18 449 0 881 1 0073 50 C ATOM 9921 C LYS C 339 8596 44806 10901 1006613 C ATOM 9837 O GLY C 328 22 632 19 362 0 656 1 00 73 50 C ATOM 9922 O LYS C 339 8185 44529 9778 1005879 C ATOM 9838 N LYS C 329 21 001 17 999 -0039 1 0068 45 C ATOM 9923 N VAL C 340 7836 45380 11819 1006563 C ATOM 9839 CA LYS C 329 21 039 18 530 -1 392 1 00 6845 C ATOM 9924 CA VAL C 340 6464 45775 11517 I 006306 C ATOM 9840 CB LYS C 329 20729 17403 -2 375 1 00198 57 C ATOM 9925 CB VAL C 340 5492 45310 12604 1006941 C ATOM 9841 CG LYS C 329 21 775 16 304 -2 373 1 00198 57 C ATOM 9926 CGl VAL C 340 4092 45783 12275 1005487 C ATOM 9842 CD LYS C 329 21 671 15 474 -3 634 1 00198 57 C ATOM 9927 CG2 VAL C 340 5545 43801 12732 1005487 C ATOM 9843 CE LYS C 329 22 751 14410 -3 715 1 00 88 33 C ATOM 9928 C VAL C 340 6419 47295 11470 1006563 C ATOM 9844 NZ LYS C 329 22 634 13 643 -4 995 ] 00 88 33 C ATOM 9929 O VALC 340 6799 47938 12431 1006248 C ATOM 9845 C LYS C 329 20248 19 783 -1 801 1 00 68 45 C ATOM 9930 N THR C 341 5955 47875 10369 1009139 C ATOM 9846 O LYS C 329 20 073 20 019 -2 997 1 00 68 45 C ATOM 9931 CA THR C 341 5897 49328 10269 1008729 C ATOM 9847 N ILE C 330 19 777 20 593 -0 853 1 00 69 95 C ATOM 9932 CB THR C 341 6600 49820 9003 1009894 C ATOM 9848 CA ILE C 330 19 045 21 811 -1 224 1 0069 95 C ATOM 9933 OGl THR C 341 7970 49408 9038 1008030 C ATOM 9849 CB ILE C 330 17499 21 622 -1 158 1 0063 51 C ATOM 9934 CG2 THR C 341 6530 51338 8909 1008030 C ATOM 9850 CG2 ILE C 330 17074 20439 -2 020 1 006443 C ATOM 9935 C THR C 341 4472 49856 10270 1008944 C ATOM 9851 CGl ILE C 330 17042 21 440 0291 1 00 6443 C ATOM 9936 O THR C 341 3560 49225 9734 1009104 C ATOM 9852 CDl ILE C 330 15 551 21 623 0474 1 00 6443 C ATOM 9937 N GLY C 342 4289 51023 10875 1009513 C ATOM 9853 C ILE C 330 19437 22 975 -0 315 1 00 69 95 C ATOM 9938 CA GLY C 342 2971 51615 10935 1009930 C ATOM 9854 O ILE C 330 20 120 22 775 0 692 1 00 69 95 C ATOM 9939 C GLY C 342 2836 52836 10051 1009827 C ATOM 9855 N PRO C 331 19 011 24207 -0656 1 0063 43 C ATOM 9940 O GLY C 342 2638 53940 10548 1009254 C ATOM 9856 CD PRO C 331 18 158 24 594 -1 792 1 00 63 75 C ATOM 9941 N ASN C 343 2950 52646 8741 10010057 C ATOM 9857 CA PRO C 331 19341 25 382 0 156 1 00 63 43 C ATOM 9942 CA ASN C 343 2810 53752 7796 10010698 C ATOM 9858 CB PRO C 331 18 394 26444 -0 380 1 00200 84 C ATOM 9943 CB ASN C 343 3170 53294 6382 10017408 C ATOM 9859 CG PRO C 331 18314 26 101 1 802 1 00 63 75 C ATOM 9944 CG ASN C 343 4523 52627 6312 10015388 C ATOM 9860 C PRO C 331 19 128 25 127 1 635 1 00 63 43 C ATOM 9945 ODl ASN C 343 5549 53244 6605 10015388 C ATOM 9861 O PRO C 331 18 123 24 533 2 025 1 00 63 43 C ATOM 9946 ND2 ASN C 343 4536 51357 5924 10015388 C ATOM 9862 N LYS C 332 20 077 25 565 2 454 1 00 52 99 C ATOM 9947 C ASN C 343 1355 54204 7810 10010504 C ATOM 9863 CA LYS C 332 19972 25 390 3 896 1 00 53 61 C ATOM 9948 O ASN C 343 0596 53857 8712 1009367 C ATOM 9864 CB LYS C 332 21 312 25 693 4555 1 00122 66 C ATOM 9949 N GLU C 344 0967 54976 6806 10016005 C ATOM 9865 CG LYS C 332 21 772 27 113 4314 1 009420 C ATOM 9950 CA GLU C 344 -0408 55434 6708 10016005 C ATOM 9866 CD LYS C 332 22 808 27537 5 329 1 009420 C ATOM 9951 CB GLU C 344 0673 56509 7761 10020084 C ATOM 9867 CE LYS C 332 23 094 29 024 5 221 1 009420 C ATOM 9952 CG GLU C 344 -1 166 55957 9097 10019023 C ATOM 9868 NZ LYS C 332 24014 29486 6300 1 009420 C ATOM 9953 CD GLU C 344 -1279 56994 10205 10019023 C ATOM 9869 C LYS C 332 18 905 26343 4 458 1 00 52 68 C ATOM 9954 OEl GLU C 344 -0239 57393 10758 10019023 C ATOM 9870 O LYS C 332 18 573 27359 3 840 1 00 50 77 C ATOM 9955 OE2 GLU C 344 -2411 57407 10535 10019023 C ATOM 9871 N ASP C 333 18 368 26 009 5 627 1 00 6044 C ATOM 9956 C GLU C 344 -0729 55921 5294 10016005 C ATOM 9872 CA ASP C 333 17 361 26 846 6264 1 0059 90 C ATOM 9957 O GLU C 344 -0264 56966 4850 10016005 C ATOM 9873 CB ASP C 333 16 857 26 186 7544 1 00136 89 C ATOM 9958 N LEU C 345 -1553 55136 4602 10020084 C ATOM 9874 CG ASP C 333 15 673 25 282 7302 1 0010448 C ATOM 9959 CA LEU C 345 -1951 55402 3221 10020084 C ATOM 9S75 ODl ASP C 333 15 641 24608 6 255 1 00104 48 C ATOM 9960 CB LEU C 345 -2536 54116 2613 10020084 C ATOM 9876 OD2 ASP C 333 14 775 25 240 8 165 1 00104 48 C ATOM 9961 CG LEU C 345 -1624 52879 2554 10016621 C ATOM 9877 C ASP C 333 17 982 28 185 6 593 1 00 63 75 C ATOM 9962 CDl LEU C 345 -2353 51728 1866 10016621 C ATOM 9878 O ASP C 333 19 144 28259 6 983 1 00 63 40 C ATOM 9963 CD2 LEU C 345 -0343 53213 1799 10016621 C ATOM 9879 N THR C 334 17 209 29 249 6430 1 00 69 18 C ATOM 9964 C LEU C 345 -2897 56587 2940 10020084 C ATOM 9880 CA THR C 334 17705 30589 6 717 1 006890 C ATOM 9965 O LEU C 345 -3731 56521 2036 10020084 C ATOM 9881 CB THR C 334 18 118 31 322 5415 1 009822 C ATOM 9966 N GLU C 346 -2759 57665 3707 10015412 C 65251/C766

ATOM 9967 CA GLU C 346 -3551 58890 3536 10015412 C ATOM 10052 ND2 ASN C 357 13663 42831 6275 1007277 C ATOM 9968 CB GLU C 346 -3228 59488 2174 10016708 C ATOM 10053 C ASN C 357 14407 38264 5036 1005155 C ATOM 9969 CG GLU C 346 -1742 59423 1874 10015251 C ATOM 10054 O ASN C 357 14893 37720 6032 1005443 C ATOM 9970 CD GLU C 346 -1311 60390 0802 10015251 C ATOM 10055 N SER C 358 14618 37876 3785 1004888 C ATOM 9971 OEl GLU C 346 -1386 61611 1048 10015251 C ATOM 10056 CA SER C 358 15418 36725 3392 1005618 C ATOM 9972 OE2 GLU C 346 -0898 59931 0283 10015251 C ATOM 10057 CB SER C 358 16863 37163 3117 1006978 C ATOM 9973 C GLU C 346 -5075 58878 3750 10015412 C ATOM 10058 OG SER C 358 17497 37597 4296 1006812 C ATOM 9974 O GLU C 346 -5567 59405 4751 10015412 C ATOM 10059 C SER C 358 15390 35505 4325 1006090 C ATOM 9975 N ASP C 347 -5827 58304 2817 10017633 C ATOM 10060 O SER C 358 16210 35369 5237 1005645 C ATOM 9976 CA ASP C 347 -7284 58278 2952 10017633 C ATOM 10061 N PHE C 359 14433 34618 4055 1005544 C ATOM 9977 CB ASP C 347 -7933 57686 1693 10016988 C ATOM 10062 CA PHE C 359 14225 33373 4795 1004975 C ATOM 9978 CG ASP C 347 -7960 56169 1702 10016988 C ATOM 10063 CB PHE C 359 12829 33390 5422 1005082 C ATOM 9979 ODl ASP C 347 -6876 55552 1726 10016988 C ATOM 10064 CG PHE C 359 11736 33843 4483 1004542 C ATOM 9980 OD2 ASP C 347 -9071 55595 1685 10016988 C ATOM 10065 CDl PHE C 359 11 150 32956 3577 1004542 C ATOM 9981 C ASP C 347 -7763 57511 4189 10017633 C ATOM 10066 CD2 PHE C 359 11276 35161 4518 1004542 C ATOM 9982 O ASP C 347 -8735 57907 4835 10017633 C ATOM 10067 CEl PHE C 359 10120 33372 2718 1004542 C ATOM 9983 N GLY C 348 -7083 56416 4516 10015615 C ATOM 10068 CE2 PHE C 359 10245 35590 3665 1004542 C ATOM 9984 CA GLY C 348 -7463 55625 5677 10015346 C ATOM 10069 CZ PHE C 359 9667 34690 2764 1004542 C ATOM 9985 C GLY C 348 -6629 55973 6894 10015042 C ATOM 10070 C PHE C 359 14335 32253 3765 1005634 C ATOM 9986 O GLY C 348 -5509 56370 6767 10014543 C ATOM 10071 O PHE C 359 13946 32474 2619 1005389 C ATOM 9987 N ASN C 349 -7170 55831 8091 10020084 C ATOM 10072 N TYR C 360 14850 31067 4108 10012762 C ATOM 9988 CA ASN C 349 -6402 56167 9285 10020084 C ATOM 10073 CA TYR C 360 14918 30086 3032 10012740 C ATOM 9989 CB ASN C 349 -7200 55785 10534 10018375 C ATOM 10074 CB TYR C 360 16015 29026 3157 10018699 C ATOM 9990 CG ASN C 349 -8020 54525 10339 10016893 C ATOM 10075 CG TYR C 360 15769 27984 2058 1007413 C ATOM 9991 ODl ASN C 349 -8910 54470 9488 10016893 C ATOM 10076 CDl TYR C 360 15489 28391 0742 1007413 C ATOM 9992 ND2 ASN C 349 -7726 53506 11 131 10016893 C ATOM 10077 CEl TYR C 360 15077 27482 -0238 1007413 C ATOM 9993 C ASN C 349 -4989 55565 9342 10020084 C ATOM 10078 CD2 TYR C 360 15646 26625 2353 1007413 C ATOM 9994 O ASN C 349 -4021 56236 8989 10020084 C ATOM 10079 CE2 TYR C 360 15240 25700 1368 1007413 C ATOM 9995 N MET C 350 -4865 54310 9766 10011677 C ATOM 10080 CZ TYR C 360 14953 26137 0080 1007413 C ATOM 9996 CA MET C 350 -3549 53680 9877 10011286 C ATOM 10081 OH TYR C 360 14540 25237 -0883 1007413 C ATOM 9997 CB MET C 350 -3260 53380 11354 10018720 C ATOM 10082 C TYR C 360 13671 29330 2659 10012849 C ATOM 9998 CG MET C 350 -1925 52708 11621 10014188 C ATOM 10083 O TYR C 360 13022 29691 1686 10013442 C ATOM 9999 SD MET C 350 -1602 52511 13380 10014188 C ATOM 10084 N PRO C 361 13334 28254 3390 1005794 C ATOM 10000 CE MET C 350 -0435 53857 13651 10014188 C ATOM 10085 CD PRO C 361 13630 27927 4798 1003870 C ATOM 10001 C MET C 350 -3360 52406 9045 10011000 C ATOM 10086 CA PRO C 361 12108 27596 2907 1005353 C ATOM 10002 O MET C 350 4325 51733 8687 10010643 C ATOM 10087 CB PRO C 361 11729 26650 4051 1003794 C ATOM 10003 N THR C 351 -2102 52090 8741 1009832 C ATOM 10088 CG PRO C 361 12323 27319 5269 1003870 C ATOM 10004 CA THR C 351 -I 758 50895 7971 1009628 C ATOM 10089 C PRO C 361 11 127 28726 2607 1006093 C ATOM 10005 CB THR C 351 -1421 51246 6496 1009391 C ATOM 10090 O PRO C 361 10698 29455 3495 1005810 C ATOM 10006 OGl THR C 351 -1 818 50166 5653 1006103 C ATOM 10091 N PRO C 362 10821 28921 1315 1006379 C ATOM 10007 CG2 THR C 351 0078 51446 6298 1006103 C ATOM 10092 CD PRO C 362 11231 27988 0249 1003987 C ATOM 10008 C THR C 351 -0549 50187 8606 1009051 C ATOM 10093 CA PRO C 362 9923 29963 0793 1005750 C ATOM 10009 O THR C 351 0431 50827 8986 1008210 C ATOM 10094 CB PRO C 362 9956 29733 -0718 1003987 C ATOM 10010 N LEU C 352 -0624 48866 8735 1005029 C ATOM 10095 CG PRO C 362 10212 28264 -0819 1003987 C ATOM 10011 CA LEU C 352 0476 48097 9311 1005331 C ATOM 10096 C PRO C 362 8512 30064 1339 1006010 C ATOM 10012 CB LEU C 352 -0027 47231 10458 1009249 C ATOM 10097 O PRO C 362 7844 31080 1 141 1006486 C ATOM 10013 CG LEU C 352 0196 48045 11740 1007355 C ATOM 10098 N ASP C 363 8054 29024 2025 1004772 C ATOM 10014 CDl LEU C 352 -0959 47257 12789 1007355 C ATOM 10099 CA ASP C 363 6714 29048 2587 1004757 C ATOM 10015 CD2 LEU C 352 1 177 48433 12243 1007355 C ATOM 10100 CB ASP C 363 6184 27618 2845 1008350 C ATOM 10016 C LEU C 352 1 132 47241 8251 1004999 C ATOM toioi CG ASP C 363 7195 26710 3545 1007771 C ATOM 10017 O LEU C 352 0461 46620 7427 1004561 C ATOM 10102 ODl ASP C 363 8308 26512 2999 1007771 C ATOM 10018 N GLU C 353 2455 47224 8265 1007785 C ATOM 10103 OD2 ASP C 363 6862 26180 4633 1007771 C ATOM 10019 CA GLU C 353 3206 46460 7285 1007410 C ATOM 10104 C ASP C 363 6720 29855 3866 10051 11 C ATOM 10020 CB GLU C 353 3907 47408 6326 10014284 C ATOM 10105 O ASP C 363 7504 29595 4770 1004761 C ATOM 10021 CG GLU C 353 4702 46712 5256 10010139 C ATOM 10106 N VAL C 364 5868 30869 3912 1004677 C ATOM 10022 CD GLU C 353 5449 47692 4380 10010139 C ATOM 10107 CA VAL C 364 5739 31714 5088 1004909 C ATOM 10023 OEl GLU C 353 4796 48585 3802 10010139 C ATOM 10108 CB VAL C 364 6566 33016 4976 1005892 C ATOM 10024 OE2 GLU C 353 6688 47573 4270 10010139 C ATOM 10109 CGl VAL C 364 6052 34038 5947 1003731 C ATOM 10025 C GLU C 353 4232 45562 7956 1007735 C ATOM 10110 CG2 VAL C 364 7999 32744 5318 1003731 C ATOM 10026 O GLU C 353 5166 46036 8595 1007813 C ATOM 10111 C VAL C 364 4280 32087 5227 1005643 C ATOM 10027 N CYS C 354 4040 44259 7807 1007150 C ATOM 10112 O VAL C 364 3590 32334 4241 1004817 C ATOM 10028 CA CYS C 354 4932 43264 8378 1007178 C ATOM 10113 N ILE C 365 3801 32103 6457 1005916 C ATOM 10029 C CYS C 354 5857 42832 7254 1007287 C ATOM 10114 CA ILE C 365 2431 32487 6689 1005321 C ATOM 10030 O CYS C 354 5393 42373 6213 10071 57 C ATOM 10115 CB ILE C 365 1554 31285 7049 1008041 C ATOM 10031 CB CYS C 354 4117 42064 8853 10012198 C ATOM 10116 CG2 ILE C 365 0169 31761 7454 1005685 C ATOM 10032 SG CYS C 354 4968 40890 9953 1009917 C ATOM 10117 CGl ILE C 365 1460 30359 5834 1005685 C ATOM 10033 N THR C 355 7160 42992 7436 1006018 C ATOM 10118 CDl ILE C 365 0571 29146 6023 1005685 C ATOM 10034 CA THR C 355 8077 42579 6384 1004954 C ATOM 10119 C ILE C 365 2419 33522 7789 1005997 C ATOM 10035 CB THR C 355 8852 43768 5769 10012819 C ATOM 10120 O ILE C 365 3234 33494 8711 1006074 C ATOM 10036 OGl THR C 355 10172 43817 6314 1007734 C ATOM 10121 N THR C 366 1477 34440 7673 1003814 C ATOM 10037 CG2 THR C 355 8145 45076 6054 1007734 C ATOM 10122 CA THR C 366 1363 35532 8596 1004642 C ATOM 10038 C THR C 355 9068 41569 6938 1006303 C ATOM 10123 CB THR C 366 1749 36823 7858 1007248 C ATOM 10039 O THR C 355 9711 41798 7966 1005583 C ATOM 10124 OGl THR C 366 2831 37444 8543 1006016 C ATOM 10040 N VAL C 356 9168 40444 6242 1004718 C ATOM 10125 CG2 THR C 366 0578 37782 7762 1006016 C ATOM 10041 CA VAL C 356 10044 39353 6620 1004290 C ATOM 10126 C THR C 366 -0034 35651 9170 1005540 C ATOM 10042 CB VAL C 356 9251 38052 6649 1006219 C ATOM 10127 O THR C 366 -1024 35530 8449 1005464 C ATOM 10043 CGl VAL C 356 10083 36944 7253 1004672 C ATOM 10128 N LYS C 367 -0103 35887 10475 1004419 C ATOM 10044 CG2 VAL C 356 7980 38272 7438 1004672 C ATOM 10129 CA LYS C 367 -1374 36062 11 168 1004739 C ATOM 10045 C VAL C 356 11 154 39290 5578 1005174 C ATOM 10130 CB LYS C 367 -1626 34922 12153 1007149 C ATOM 10046 O VAL C 356 10901 39084 4392 1005285 C ATOM 10131 CG LYS C 367 -1972 33616 11496 1006250 C ATOM 10047 N ASN C 357 12388 39463 6037 1005117 C ATOM 10132 CD LYS C 367 -2511 32607 12499 I 006250 C ATOM 10048 CA ASN C 357 13537 39490 5143 1 004739 C ATOM 10133 CE LYS C 367 -3048 31385 11773 1006250 C ATOM 10049 CB ASN C 357 14412 40689 5479 10011885 C ATOM 10134 NZ LYS C 367 -3843 30509 12670 1006250 C ATOM 10050 CG ASN C 357 13696 41985 5254 1007277 C ATOM 10135 C LYS C 367 -1383 37374 11932 1005009 C ATOM 10051 ODl ASN C 357 13166 42226 4171 1007277 C ATOM 10136 O LYS C 367 -0447 37669 12679 1005040 C 65251/C766

ATOM 10137 N TRP C 368 -2439 3S 159 11 744 1 00 48 65 C ATOM 10222 OEl GLU C 377 5254 33823 28419 10010419 C ATOM 10138 CA TRP C 368 -2 577 39 437 12434 1 0048 71 C ATOM 10223 OE2 GLU C 377 3135 34148 28922 10010419 C

ATOM 10139 CB TRP C 368 -3 063 40 534 11 486 1 00 84 38 C ATOM 10224 C GLU C 377 2891 37787 25613 100111 16 C

ATOM 10140 CG TRP C 368 -2 027 40 941 10495 1 00 6430 C ATOM 10225 O GLU C 377 1934 37198 25103 100111 16 C

ATOM 10141 CD2 TRP C 36S -0996 41 916 10 688 1 00 64 30 C ATOM 10226 N TYR C 378 3905 38278 24901 1006391 C

ATOM 10142 CE2 TRP C 368 -0 197 41 916 9 523 1 00 64 30 C ATOM 10227 CA TYR C 378 3935 38162 23444 1006391 C

ATOM 10143 CE3 TRP C 368 -0669 42 788 11 731 1 006430 C ATOM 10228 CB TYR C 378 4569 39409 22834 1007886 C

ATOM 10144 CDl TRP C 368 -1 822 40 407 9254 1 00 6430 C ATOM 10229 CG TYR C 378 3684 40617 23002 1007886 C

ATOM 10145 NEl TRP C 368 -0 724 40 986 8 663 1 0064 30 C ATOM 10230 CDl TYR C 378 3848 41486 24080 1007886 C

ATOM 10146 CZ2 TRP C 368 0 91 1 42 757 9374 1 00 64 30 C ATOM 10231 CEl TYR C 378 2972 42557 24287 1007886 C ATOM 10147 CZ3 TRP C 368 0 431 43 621 11 581 1 00 6430 C ATOM 10232 CD2 TYR C 378 2625 40850 22127 1007886 C

ATOM 10148 CH2 TRP C 368 1 207 43 598 10 410 1 006430 C ATOM 10233 CE2 TYR C 378 1745 41914 22325 1007886 C

ATOM 10149 C TRP C 368 -3 572 39 263 13 551 1 00 50 66 C ATOM 10234 CZ TYR C 378 1924 42762 23408 1007886 C

ATOM 10150 O TRP C 368 -4741 38 986 13 299 1 00 50 85 C ATOM 10235 OH TYR C 378 1044 43799 23615 1007886 C

ATOM 10151 N ILE C 369 -3 106 39 437 14 784 1 00 66 16 C ATOM 10236 C TYR C 378 4585 36906 22868 1006391 C

ATOM 10152 CA ILE C 369 -3 951 39265 15 955 1 00 67 53 C ATOM 10237 O TYR C 378 5622 36968 22188 1006391 C

ATOM 10153 CB ILE C 369 -3 482 38 045 16 755 1 00 61 03 C ATOM 10238 N LYS C 379 3944 35771 23156 1006249 C

ATOM 10154 CG2 ILE C 369 -4 398 37 815 17 939 1 0038 71 C ATOM 10239 CA LYS C 379 4361 34456 22678 1006249 C

ATOM 10155 CGl ILE C 369 -3 416 36 827 15 833 1 003S 71 C ATOM 10240 CB LYS C 379 4957 33616 23808 1007416 C

ATOM 10156 CDl ILE C 369 -2 812 35 617 16475 1 0038 71 C ATOM 10241 CG LYS C 379 6272 34141 24365 1007416 C

ATOM 10157 C ILE C 369 -3 910 40487 16 859 1 00 69 35 C ATOM 10242 CD LYS C 379 6754 33251 25504 1007416 C ATOM 10158 O ILE C 369 -2 840 41 037 17 109 1 00 66 15 C ATOM 10243 CE LYS C 379 7985 33815 26215 1007416 C

ATOM 10159 N GLU C 370 -5 073 40917 17 344 1 00 67 72 C ATOM 10244 NZ LYS C 379 8325 33024 27438 1007416 C

ATOM 10160 CA GLU C 370 -5 132 42 067 18 238 1 007037 C ATOM 10245 C LYS C 379 3088 33799 22165 1006249 C

ATOM 10161 CB GLU C 370 -6 581 42 375 18 593 1 00115 11 C ATOM 10246 O LYS C 379 2021 33928 22768 1006249 C

ATOM 10162 CG GLU C 370 -7301 43 073 17457 1 0093 75 C ATOM 10247 N TYR C 380 3191 33 123 21033 1004347 C

ATOM 10163 CD GLU C 370 -8 794 43 158 17 661 1 0093 75 C ATOM 10248 CA TYR C 380 2037 32453 20449 1004347 C

ATOM 10164 OEl GLU C 370 -9 219 43 564 18 763 1 00 93 75 C ATOM 10249 CB TYR C 380 2198 32393 18934 1005494 C

ATOM 10165 OE2 GLU C 370 -9 542 42 826 16 715 1 00 93 75 C ATOM 10250 CG TYR C 380 1024 31795 18213 1005494 C

ATOM 10166 C GLU C 370 -4309 41 745 19478 1 0070 55 C ATOM 10251 CDl TYR C 380 -0058 32584 17845 1005494 C

ATOM 10167 O GLU C 370 4440 40 667 20 052 1 00 69 40 C ATOM 10252 CEl TYR C 380 -1 140 32040 17166 1005494 C

ATOM 10168 N SER C 371 -3 445 42 674 19 878 1 00 69 33 C ATOM 10253 CD2 TYR C 380 0997 30436 17889 1005494 C ATOM 10169 CA SER C 371 -2 556 42477 21 026 1 00 69 87 C ATOM 10254 CE2 TYR C 380 -0084 29881 17216 1005494 C

ATOM 10170 CB SER C 371 -1 660 43 701 21 212 1 00 86 18 C ATOM 10255 CZ TYR C 380 -1 147 30687 16855 1005494 C

ATOM 10171 OG SER C 371 -2 436 44 856 21 466 1 00 75 26 C ATOM 10256 OH TYR C 380 2214 30142 16177 1005494 C

ATOM 10172 C SER C 371 -3 221 42 146 22 356 1 00 69 14 C ATOM 10257 C TYR C 380 2030 31049 21025 1004347 C

ATOM 10173 O SER C 371 -2 584 41 566 23 234 1 00 7008 C ATOM 10258 O TYR C 380 2932 30260 20735 I 004347 C

ATOM 10174 N GLU C 372 4485 42 520 22 518 1 0071 12 C ATOM 10259 N VAL C 381 1029 30742 21845 1004905 C

ATOM 10175 CA GLU C 372 -5 193 42 229 23 760 1 0069 67 C ATOM 10260 CA VAL C 381 0935 29417 22471 1004905 C

ATOM 10176 CB GLU C 372 -6 652 42 684 23 659 I 0012654 C ATOM 10261 CB VAL C 381 0114 29477 23779 1005325 C

ATOM 10177 CG GLU C 372 -7407 42 054 22 502 1 00126 54 C ATOM 10262 CGl VAL C 381 0130 28122 24459 1005325 C

ATOM 10178 CD GLU C 372 -8 905 42 245 22 604 1 00126 54 C ATOM 10263 CG2 VAL C 381 0688 30535 24702 1005325 C

ATOM 10179 OEl GLU C 372 -9 500 41 740 23 580 1 00126 54 C ATOM 10264 C VAL C 381 0296 28409 21515 1004905 C

ATOM 10180 OE2 GLU C 372 -9 489 42 895 21 708 1 00126 54 C ATOM 10265 O VAL C 381 -0840 28595 21087 1004905 C

ATOM 10181 C GLU C 372 -5 145 40 726 24 054 1 00 7428 C ATOM 10266 N ASN C 382 1029 27340 21210 10071 19 C

ATOM 10182 O GLU C 372 -4959 40307 25 199 1 0075 35 C ATOM 10267 CA ASN C 382 0572 26328 20270 1007119 C

ATOM 10183 N HIS C 373 -5 292 39 922 23 005 1 00 85 31 C ATOM 10268 CB ASN C 382 1335 25019 20459 1005124 C

ATOM 10184 CA HIS C 373 -5 298 38 474 23 132 1 00 88 80 C ATOM 10269 CG ASN C 382 1355 24152 19179 1005124 C

ATOM 10185 CB HIS C 373 -5 661 37 842 21 795 1 00 95 89 C ATOM 10270 ODl ASN C 382 0418 24166 18380 1005124 C

ATOM 10186 CG HIS C 373 -7026 38 210 21 318 1 00 65 24 C ATOM 10271 ND2 ASN C 382 2423 23381 19006 1005124 C

ATOM 10187 CD2 HIS C 373 -7 447 38 765 20 156 1 00 65 24 C ATOM 10272 C ASN C 382 -0917 26014 20270 10071 19 C

ATOM 10188 NDl HIS C 373 -8 153 38024 22 086 1 00 65 24 C ATOM 10273 O ASN C 382 -I 667 26487 19408 10071 19 C

ATOM 10189 CEl HIS C 373 -9212 38450 21 418 1 00 65 24 C ATOM 10274 N GLY C 383 -1365 25214 21225 1003939 C

ATOM 10190 NE2 HIS C 373 -8 810 38905 20244 1 00 65 24 C ATOM 10275 CA GLY C 383 -2776 24861 21211 1003939 C

ATOM 10191 C HIS C 373 -4 011 37 859 23 649 1 00 84 57 C ATOM 10276 C GLY C 383 -3802 25923 21573 1003939 C

ATOM 10192 O HIS C 373 -3 974 36 665 23 939 1 00 8041 C ATOM 10277 O GLY C 383 -4992 25649 21588 1003939 C

ATOM 10193 N PHE C 374 -2 953 38 651 23 766 1 0091 88 C ATOM 10278 N ARG C 384 -3366 27139 21858 1004621 C

ATOM 10194 CA PHE C 374 -1 704 38 104 24271 1 00 92 65 C ATOM 10279 CA ARG C 384 -4302 28182 22256 1004621 C

ATOM 10195 CB PHE C 374 -0 515 38 618 23 467 1 00 85 43 C ATOM 10280 CB ARG C 384 -3540 29317 22942 1005228 C

ATOM 10196 CG PHE C 374 -0426 38 018 22 105 1 00 65 61 C ATOM 10281 CG ARG C 384 -4419 30379 23572 1005228 C

ATOM 10197 CDl PHE C 374 -1 198 38 514 21 062 1 0065 61 C ATOM 10282 CD ARG C 384 -3604 31210 24541 1005228 C

ATOM 10198 CD2 PHE C 374 0373 36 901 21 875 1 00 65 61 C ATOM 10283 NE ARG C 384 -3036 30372 25585 1005228 C

ATOM 10199 CEl PHE C 374 -1 182 37 907 19 815 1 0065 61 C ATOM 10284 CZ ARG C 384 -2133 30776 26471 1005228 C

ATOM 10200 CE2 PHE C 374 0 395 36285 20624 1 00 65 61 C ATOM 10285 NHl ARG C 384 -1690 32016 26443 1005228 C

ATOM 10201 CZ PHE C 374 -0385 36790 19 595 1 00 65 61 C ATOM 10286 NH2 ARG C 384 -1667 29931 27386 1005228 C

ATOM 10202 C PHE C 374 1 513 38 408 25 741 1 00 88 73 C ATOM 10287 C ARG C 384 -5123 28739 21 115 1004621 C ATOM 10203 O PHE C 374 -0426 38 204 26291 1 00 86 97 C ATOM 10288 O ARG C 384 -4670 28784 19972 1004621 C

ATOM 10204 N LYS C 375 -2 587 38 881 26369 1 0012827 C ATOM 10289 N TYR C 385 -6337 29165 21435 1005285 C

ATOM 10205 CA LYS C 375 -2 595 39213 27 790 1 00130 90 C ATOM 10290 CA TYR C 385 -7223 29742 20432 1005285 C

ATOM 10206 CB LYS C 375 -3 213 38 063 28 600 1 00138 04 C ATOM 10291 CB TYR C 385 -8686 29522 20823 1005605 C

ATOM 10207 CG LYS C 375 -4 741 38005 28 612 1 00111 88 C ATOM 10292 CG TYR C 385 -9636 30281 19937 1005605 C

ATOM 10208 CD LYS C 375 -5 327 37599 27 268 1 00111 88 C ATOM 10293 CDl TYR C 385 -9902 29842 18638 1005605 C

ATOM 10209 CE LYS C 375 -6 850 37455 27 350 1 00111 88 C ATOM 10294 CEl TYR C 385 10706 30581 17779 1005605 C

ATOM 10210 NZ LYS C 375 -7484 37 104 26 036 1 00111 88 C ATOM 10295 CD2 TYR C 385 -10207 31484 20362 1005605 C

ATOM 10211 C LYS C 375 -1 219 39 544 28365 1 00135 92 C ATOM 10296 CE2 TYR C 385 -11012 32238 19514 1005605 C

ATOM 10212 O LYS C 375 -0 787 38 926 29 336 1 00138 18 C ATOM 10297 CZ TYR C 385 -11257 31779 18217 1005605 C

ATOM 10213 N GLY C 376 -0527 40 504 27761 1 00 8798 C ATOM 10298 OH TYR C 385 -12037 32519 17350 1005605 C ATOM 10214 CA GLY C 376 0779 40 895 28271 1 00 8 ⁷ 98 C ATOM 10299 C TYR C 385 -6971 31252 20285 1005285 C

ATOM 10215 C GLY C 376 2 003 40 098 27 839 1 00 8798 C ATOM 10300 O TYR C 385 -6717 31942 21276 1005285 C

ATOM 10216 O GLY C 376 3 108 40 646 27 783 1 00 8798 C ATOM 10301 N TYR C 386 -7043 31764 19057 1005134 C

ATOM 10217 N GLU C 377 1 834 38 809 27 555 1 00111 16 C ATOM 10302 CA TYR C 386 6839 33196 18814 1005134 C

ATOM 10218 CA GLU C 377 2 962 37990 27 125 1 00111 16 C ATOM 10303 CB TYR C 386 -5390 33519 18410 1004413 C

ATOM 10219 CB GLU C 377 2946 36635 27 836 1 00104 19 C ATOM 10304 CG TYR C 386 -4316 33232 19423 1004413 C

ATOM 10220 CG GLU C 377 4225 35 832 27640 1 00104 19 C ATOM 10305 CDl TYR C 386 -3591 32044 19372 1004413 C

ATOM 10221 CD GLU C 377 4205 34506 28381 1 00104 19 C ATOM 10306 CEl TYRC 386 -2555 31794 20273 1004413 C 65251/C766

ATOM 10307 CD2 TYR C 386 -3 986 34 166 20405 1 00 44 13 C ATOM 10392 O TYR C 395 -7 971 32 008 0 352 1 0053 78 C ATOM 10308 CE2 TYR C 386 -2 953 33 930 21 308 1 0044 13 C ATOM 10393 N GLU C 396 -7409 29 825 0 412 1 00 6690 C ATOM 10309 CZ TYR C 386 -2237 32 744 21 237 1 0044 13 C ATOM 10394 CA GLU C 396 -7210 29 778 1 860 1 0066 90 C ATOM 10310 OH TYR C 386 -1 179 32 509 22 094 1 0044 13 C ATOM 10395 CB GLU C 396 -7 828 28 512 2 451 1 0094 83 C ATOM 10311 C TYR C 386 -7 707 33 720 17677 1 00 51 34 C ATOM 10396 CG GLU C 396 -9250 28 229 2 006 1 0094 83 C ATOM 10312 O TYR C 386 -7 675 33 181 16575 1 00 51 34 C ATOM 10397 CD GLU C 396 -9 712 26 838 2 418 1 0094 83 C ATOM 10313 N PRO C 387 -8 507 34 766 17 931 1 00 6440 C ATOM 10398 OEl GLU C 396 -9 000 25 861 2 092 1 0094 83 C ATOM 10314 CD PRO C 387 -8 883 35 338 19 234 1 00 82 91 C ATOM 10399 OE2 GLU C 396 -10 781 26 720 3 062 1 00 94 83 C ATOM 10315 CA FRO C 387 -9338 35 317 16 851 1 006440 C ATOM 10400 C GLU C 396 -5 702 29730 2 068 1 006690 C ATOM 10316 CB PRO C 387 -10 142 36393 17 562 1 00 82 91 C ATOM 10401 O GLU C 396 -5 002 29 038 1 327 1 00 6690 C ATOM 10317 CG PRO C 387 -10271 35 841 18 957 1 00 82 91 C ATOM 10402 N PRO C 397 -5 176 30467 3 064 1 0055 43 C ATOM 10318 C PRO C 387 -8 269 35 906 15 921 1 00 6440 C ATOM 10403 CD PRO C 397 -5 845 31 251 4 1 15 1 00 63 83 C ATOM 10319 O PRO C 387 -7 257 36397 16 423 1 00 64 40 C ATOM 10404 CA PRO C 397 -3 723 30 431 3 286 1 00 55 43 C ATOM 10320 N GLU C 388 -8 445 35 897 14601 1 00 79 00 C ATOM 10405 CB PRO C 397 -3 548 31 213 4 586 1 00 63 83 C ATOM 10321 CA GLU C 388 -7329 36 394 13 814 1 00 79 00 C ATOM 10406 CG PRO C 397 -4 889 31 096 5 262 1 00 63 83 C ATOM 10322 CB GLU C 388 -6483 35 208 13 361 1 00108 73 C ATOM 10407 C PRO C 397 3 234 28 995 3 383 1 00 55 43 C ATOM 10323 CG GLU C 388 -7 147 34 332 12 324 1 00108 73 C ATOM 10408 O PRO C 397 -3 823 28 171 4080 1 00 55 43 C ATOM 10324 CD GLU C 388 -6 176 33 346 11 705 1 00108 73 C ATOM 10409 N GLY C 398 -2 158 28 699 2 672 1 0047 53 C ATOM 10325 OEl GLU C 388 -5 161 33 798 U 138 1 00108 73 C ATOM 10410 CA GLY C 398 -1 649 27 343 2 654 1 00 47 53 C ATOM 10326 OE2 GLU C 388 -6423 32 124 11 784 1 00108 73 C ATOM 10411 C GLY C 398 -1 703 26 852 1 217 1 0047 53 C ATOM 10327 C GLU C 388 -7400 37 361 12 646 1 00 79 00 C ATOM 10412 O GLY C 398 -0 763 26 182 0 757 1 004753 C ATOM 10328 O GLU C 388 -6450 37396 11 861 1 00 79 00 C ATOM 10413 N GLU C 399 -2 794 27 181 0 509 1 004860 C ATOM 10329 N TRP C 389 -8456 38 149 12 492 1 00 63 56 C ATOM 10414 CA GLU C 399 -2 953 26 784 -0900 1 0048 60 C ATOM 10330 CA TRP C 389 -8 455 39 102 11 369 1 0063 56 C ATOM 10415 CB GLU C 399 -4 389 27 026 -1 383 1 00 67 07 C ATOM 10331 CB TRP C 389 -7 391 40 186 11 593 1 0011625 C ATOM 10416 CG GLU C 399 -5 446 26 365 -0 523 1 00 67 07 C ATOM 10332 CG TRP C 389 -7 875 41 473 12 179 1 0011625 C ATOM 10417 CD GLU C 399 -6 863 26 574 -1 033 1 00 67 07 C ATOM 10333 CD2 TRP C 389 -9238 41 869 12 410 1 00116 25 C ATOM 10418 OEl GLU C 399 -7 188 27710 -1 431 1 00 6707 C ATOM 10334 CE2 TRP C 389 -9205 43 174 12950 1 0011625 C ATOM 10419 OE2 GLU C 399 -7664 25 612 -1 017 1 006707 C ATOM 10335 CE3 TRP C 389 -10485 41 250 12 211 1 00116 25 C ATOM 10420 C GLU C 399 -1 981 27 649 -1 709 1 0048 60 C ATOM 10336 CDl TRP C 389 -7099 42 524 12 579 1 00116 25 C ATOM 10421 O GLU C 399 -1 869 28 846 -1 460 1 0048 60 C ATOM 10337 NEl TRP C 389 -7 888 43 548 13 042 1 00116 25 C ATOM 10422 N PRO C 400 -1 254 27 061 -2 673 1 0075 85 C ATOM 10338 CZ2 TRP C 389 -10 371 43 873 13 296 1 00116 25 C ATOM 10423 CD PRO C 400 -1 163 25 666 -3 123 1 00 47 83 C ATOM 10339 CZ3 TRP C 389 -11 644 41 946 12 554 1 00116 25 C ATOM 10424 CA PRO C 400 -0 330 27 907 -3 423 1 00 70 93 C ATOM 10340 CH2 TRP C 389 -11 576 43 244 13 090 1 00116 25 C ATOM 10425 CB PRO C 400 0 307 26940 4420 1 00 9644 C ATOM 10341 C TRP C 389 -8 143 38 424 10 036 1 00 63 56 C ATOM 10426 CG PRO C 400 -0 667 25 835 -4 520 1 0047 83 C ATOM 10342 O TRP C 389 -7056 38 618 9479 1 00 63 56 C ATOM 10427 C PRO C 400 -0 979 29 114 -4081 1 0061 68 C ATOM 10343 N GLY C 390 -9 085 37 642 9 520 1 00 75 39 C ATOM 10428 O PRO C 400 -0300 30 084 -4417 1 0061 89 C ATOM 10344 CA GLY C 390 -8 845 36 961 8262 1 00 75 39 C ATOM 10429 N GLY C 401 -2 294 29 078 -4 243 1 00 50 15 C ATOM 10345 C GLY C 390 -8 639 37 879 7 067 1 00 75 39 C ATOM 10430 CA GLY C 401 -2 974 30 211 -4 855 1 0049 71 C ATOM 10346 O GLY C 390 -9 092 39 021 7 067 1 00 75 39 C ATOM 10431 C GLY C 401 -3 151 31 437 -3 962 1 0049 50 C ATOM 10347 N ARG C 391 -7 936 37377 6 053 1 00 89 36 C ATOM 10432 O GLY C 401 -3 590 32 487 -4429 1 005021 C ATOM 10348 CA ARG C 391 -7694 38 126 4 824 1 00 89 36 C ATOM 10433 N PHE C 402 -2 821 31 326 -2 678 1 00 59 61 C ATOM 10349 CB ARG C 391 -6335 37 738 4233 10010479 C ATOM 10434 CA PHE C 402 -2 978 32466 -1 788 1 00 59 61 C ATOM 10350 CG ARG C 391 -5 152 37 981 5171 10010479 C ATOM 10435 CB PHE C 402 -2 811 32 047 -0 337 1 00156 44 C ATOM 10351 CD ARG C 391 -4449 39 326 4921 10010479 C ATOM 10436 CG PHE C 402 -3 425 33 009 0 624 1 00 54 77 C ATOM 10352 NE ARG C 391 -3 356 39 227 3947 10010479 C ATOM 10437 CDl PHE C 402 -4 804 33 036 0 805 1 00 54 77 C ATOM 10353 CZ ARG C 391 -3 513 39 149 262410010479 C ATOM 10438 CD2 PHE C 402 -2 635 33 923 1 314 1 00 54 77 C ATOM 10354 NHl ARG C 391 -4 728 39 163 2090 10010479 C ATOM 10439 CEl PHE C 402 -5 395 33 961 1 658 1 00 54 77 C ATOM 10355 NH2 ARG C 391 244839046 1833 10010479 C ATOM 10440 CE2 PHE C 402 -3 209 34 852 2 167 1 00 5477 C ATOM 10356 C ARG C 391 -882537742 3860 1008936 C ATOM 10441 CZ PHE C 402 -4596 34 873 2 340 1 00 54 77 C ATOM 10357 O ARG C 391 -9551 36779 4110 1008936 C ATOM 10442 C PHE C 402 -1 956 33 550 -2 128 1 00 59 61 C ATOM 10358 N LYS C 392 898738488 2771 1007358 C ATOM 10443 O PHE C 402 -0 762 33 267 -2257 1 00 59 61 C ATOM 10359 CA LYS C 392 -1004638188 18061007358 C ATOM 10444 N PRO C 403 -2418 34 809 -2273 1 0093 77 C ATOM 10360 CB LYS C 392 -1089239434 1532 1009402 C ATOM 10445 CD PRO C 403 -3 828 35 200 -2 141 1 0049 25 C ATOM 10361 CG LYS C 392 -12021 39191 0551 1009402 C ATOM 10446 CA PRO C 403 -1 602 35 983 -2 602 1 00 93 77 C ATOM 10362 CD LYS C 392 1268540483 0124 1009402 C ATOM 10447 CB PRO C 403 2 637 37074 -2 884 1 00154 08 C ATOM 10363 CE LYS C 392 -1368740237 -0998 1009402 C ATOM 10448 CG PRO C 403 -3 905 36344 -3 097 1 00 4925 C ATOM 10364 NZ LYS C 392 -1420941513 -1571 1009402 C ATOM 10449 C PRO C 403 -0 667 36425 -1 488 1 00 93 77 C ATOM 10365 C LYS C 392 -947237661 0493 1007358 C ATOM 10450 O PRO C 403 -1 099 37 070 -0530 1 0093 77 C ATOM 10366 O LYS C 392 -876338374 -0213 1007358 C ATOM 10451 N TRP C 404 0 607 36 076 -1 606 1 00 73 97 C ATOM 10367 N SER C 393 -9781 36406 0177 1006587 C ATOM 10452 CA TRP C 404 1 597 36 490 -0619 1 0073 97 C ATOM 10368 CA SER C 393 -929735774 -1045 1006587 C ATOM 10453 CB TRP C 404 2314 35 290 0016 1 00 63 24 C ATOM 10369 CB SER C 393 -781535394 -0899 1007344 C ATOM 10454 CG TRP C 404 1 516 34 526 I 040 1 0056 48 C ATOM 10370 OG SER C 393 -734234706 -2052 1007344 C ATOM 10455 CD2 TRP C 404 0 985 35 022 2 284 1 005648 C ATOM 10371 C SER C 393 -1011434523 -1330 1006587 C ATOM 10456 CE2 TRP C 404 0 343 33 943 2 921 1 00 5648 C ATOM 10372 O SER C 393 -1074233977 -0429 1006587 C ATOM 10457 CE3 TRP C 404 0992 36271 2918 1 005648 C ATOM 10373 N ASN C 394 -1011434073 -2580 1006579 C ATOM 10458 CDl TRP C 404 1 179 33 211 0 984 1 00 5648 C ATOM 10374 CA ASN C 394 -1084832866 2928 1006579 C ATOM 10459 NEl TRP C 404 0477 32 851 2 106 1 00 5648 C ATOM 10375 CB ASN C 394 -11073 32778 -4427 1007181 C ATOM 10460 CZ2 TRP C 404 -0288 34070 4 164 1 00 5648 C ATOM 10376 CG ASN C 394 -1208433783 -4909 1007181 C ATOM 10461 CZ3 TRP C 404 0 362 36398 4 162 1 00 5648 C ATOM 10377 ODl ASN C 394 -1317533903 -4343 1007181 C ATOM 10462 CH2 TRP C 404 -0 267 35 301 4 766 1 00 5648 C ATOM 10378 ND2 ASN C 394 -1173434514 -5963 1007181 C ATOM 10463 C TRP C 404 2600 37307 -1 407 1 0073 97 C ATOM 10379 C ASN C 394 -1006031661 -2464 1006579 C ATOM 10464 O TRP C 404 3 072 36 861 -2 452 1 00 73 97 C ATOM 10380 O ASN C 394 -1059530554 -2344 1006579 C ATOM 10465 N ASN C 405 2 923 38 501 -0 922 1 00 6225 C ATOM 10381 N TYR C 395 -877731892 -2207 1005378 C ATOM 10466 CA ASN C 405 3 879 39347 -1 624 1 006228 C ATOM 10382 CA TYR C 395 -788930847 -1734 1005378 C ATOM 10467 CB ASN C 405 3 718 40 799 -1 185 1 00 8475 C ATOM 10383 CB TYR C 395 -651530997 -2379 1006039 C ATOM 10468 CG ASN C 405 4265 41 767 -2 202 1 00 8475 C ATOM 10384 CG TYR C 395 -651830818 -3875 1006039 C ATOM 10469 ODl ASN C 405 5 476 41 871 -2 397 1 00 8475 C ATOM 10385 CDl TYR C 395 -662931911 -4725 1006039 C ATOM 10470 ND2 ASN C 405 3 369 42474 -2 875 1 00 84 75 C ATOM 10386 CEl TYR C 395 -661431747 -6112 1006039 C ATOM 10471 C ASN C 405 5 303 38 866 -1 359 1 00 71 22 C ATOM 10387 CD2 TYR C 395 -639729544 -4445 1006039 C ATOM 10472 O ASN C 405 6 056 39467 -0 588 1 00 6428 C ATOM 10388 CE2 TYR C 395 -638029371 -5825 1006039 C ATOM 10473 N ILE C 406 5 657 37 762 -2 000 1 0061 33 C ATOM 10389 CZ TYR C 395 -648930481 -6651 1006039 C ATOM 10474 CA ILE C 406 6974 37 184 -1 841 1 00 53 53 C ATOM 10390 OH TYR C 395 -6481 30317 8012 1006039 C ATOM 10475 CB ILE C 406 6 885 35 685 -1 508 1 00 73 34 C ATOM 10391 C TYR C 395 -775330943 -0224 1005378 C ATOM 10476 CG2 ILE C 406 8 278 35 120 -1 223 1 00 60 96 C 65251/C766

ATOM 10477 CGl ILE C 406 598835486 -0295 1006096 C ATOM 10562 N LEU C 417 935038768 2034 1004665 C ATOM 10478 CDl ILE C 406 5911 34043 0179 1006096 C ATOM 10563 CA LEU C 417 791438985 2027 1004555 C

ATOM 10479 C ILE C 406 7750 37339 -3133 1006040 C ATOM 10564 CB LEU C 417 723637845 2793 10010023 C

ATOM 10480 O ILE C 406 7184 37215 -4217 1005550 C ATOM 10565 CG LEU C 417 5890 38189 3435 1005834 C

ATOM 10481 N LYS C 407 9041 37624 -3016 1007412 C ATOM 10566 CDl LEU C 417 4792 38190 2386 1005834 C

ATOM 10482 CA LYS C 407 990637762 -4179 1006972 C ATOM 10567 CD2LEUC417 5582 37200 4506 1005834 C

ATOM 10483 CB LYS C 407 1015639234 -4521 10012247 C ATOM 10568 C LEU C 417 7496 40313 2644 1005706 C

ATOM 10484 CG LYS C 407 8921 40017 -4920 10010857 C ATOM 10569 O LEU C 417 816740842 3521 1005216 C

ATOM 10485 CD LYS C 407 9301 41392 -5448 10010857 C ATOM 10570 N THRC418 6363 40832 2191 1005877 C

ATOM 10486 CE LYS C 407 807742259 -5707 1 OOIOS 57 C ATOM 10571 CA THR C 418 582642079 2712 1005183 C ATOM 10487 NZ LYS C 407 734442585 -4449 10010857 C ATOM 10572 CB THR C 418 611743268 1767 1008449 C

ATOM 10488 C LYSC407 11213 37114 -3785 1007903 C ATOM 10573 OGl THR C 418 7505 43600 1826 1005290 C

ATOM 10489 O LYS C 407 1163737235 -2635 1007797 C ATOM 10574 CG2THRC418 5308 44486 2169 1005290 C

ATOM 10490 N LYS C 408 1184436405 -4714 1006563 C ATOM 10575 C THR C 418 4322 41930 2824 1006702 C

ATOM 10491 CA LYS C 408 1311735784 -4392 1006522 C ATOM 10576 O THR C 418 364041768 1816 1006049 C

ATOM 10492 CB LYS C 408 13486 34741 -5438 1007393 C ATOM 10577 N ASP C 419 3799 41985 4041 1004456 C

ATOM 10493 CG LYS C 408 14725 33960 -5076 1007273 C ATOM 10578 CA ASP C 419 236441852 4224 1004967 C

ATOM 10494 CD LYS C 408 14902 32783 -5995 1007273 C ATOM 10579 CB ASP C 419 205040651 5120 10012428 C

ATOM 10495 CE LYS C 408 16095 31944 -5578 1007273 C ATOM 10580 CG ASP C 419 058940251 5059 10010187 C

ATOM 10496 NZ LYS C 408 16184 30696 -6394 1007273 C ATOM 10581 ODl ASP C 419 0061 40125 3935 10010187 C

ATOM 10497 C LYS C 408 14105 36934 -4412 1006535 C ATOM 10582 OD2ASPC419 -0032 40058 6125 10010187 C ATOM 10498 O LYS C 408 14403 37462 -5469 1006392 C ATOM 10583 C ASP C 419 1783 43125 4820 1005376 C

ATOM 10499 N ASP C 409 1460237347 -3254 10010126 C ATOM 10584 O ASP C 419 2221 43580 5872 1004865 C

ATOM 10500 CA ASP C 409 15514 38479 -3253 10010144 C ATOM 10585 N LEU C 420 0787 43692 4145 1007457 C

ATOM 10501 CB ASP C 409 15805 38956 1814 1007441 C ATOM 10586 CA LEU C 420 0153 44930 4590 1007926 C

ATOM 10502 CG ASP C 409 16125 37827 -0864 1006723 C ATOM 10587 CB LEU C 420 0031 45881 3401 10013074 C

ATOM 10503 ODl ASP C 409 16943 36961 -1227 1006723 C ATOM 10588 CG LEU C 420 -014047366 3702 1008969 C

ATOM 10504 OD2 ASP C 409 15569 37823 0251 1006723 C ATOM 10589 CDl LEU C 420 1117 47883 4391 1008969 C

ATOM 10505 C ASPC409 1680838241 -4033 10010135 C ATOM 10590 CD2 LEU C 420 -0394 48129 2403 1008969 C

ATOM 10506 O ASP C 409 17151 37102 -4358 10010508 C ATOM 10591 C LEU C 420 -122844684 5204 1008183 C

ATOM 10507 N LYSC410 1748439350 -4351 10010537 C ATOM 10592 O LEU C 420 -1878 43691 4888 1008115 C

ATOM 10508 CA LYSC410 18742 39393 -5103 10011181 C ATOM 10593 N VAL C 421 -1671 45585 6080 1006555 C ATOM 10509 CB LYS C 410 1960940545 -4590 10017534 C ATOM 10594 CA VAL C 421 -297945460 6728 1006406 C

ATOM 10510 CG LYSC410 20148 40353 -3168 10011479 C ATOM 10595 CB VAL C 421 -285844742 8087 10010924 C

ATOM 10511 CD LYS C 410 19065 40492 -2094 10011479 C ATOM 10596 CGl VAL C 421 -418644768 8830 1006467 C

ATOM 10512 CE LYS C 410 1963540258 -0694 10011479 C ATOM 10597 CG2VALC421 -244443325 7857 1006467 C

ATOM 10513 NZ LYS C 410 18601 40384 0370 10011479 C ATOM 10598 C VAL C 421 -365746808 6950 1006632 C

ATOM 10514 C LYSC410 1956238111 -5073 10011063 C ATOM 10599 O VAL C 421 -303047764 7393 1006192 C

ATOM 10515 O LYSC410 1947037329 -4133 10011016 C ATOM 10600 N ARG C 422 -4945 46871 6649 1008302 C

ATOM 10516 N ASP C 411 20382 37924 -6103 1006792 C ATOM 10601 CA ARG C 422 -5724 48095 6812 1008515 C

ATOM 10517 CA ASPC411 21238 36745 -6240 1006543 C ATOM 10602 CB ARG C 422 -6944 48032 5893 1 I 0015906 C

ATOM 10518 CB ASPC411 2258637127 -6849 10019997 C ATOM 10603 CG ARG C 422 -7094 49197 4938 : I 0011965 C

ATOM 10519 CG ASP C 411 22573 37071 -8361 10019997 C ATOM 10604 CD ARG C 422 -7682 50419 5623 I 0011965 C

ATOM 10520 ODl ASP C 411 22139 36041 -8910 10019997 C ATOM 10605 NE ARG C 422 -7960 51488 4661 I I 0011965 C

ATOM 10521 OD2ASPC411 23003 38041 -9008 10019997 C ATOM 10606 CZ ARG C 422 -8587 52626 4956 1 0011965 C

ATOM 10522 C ASP C 411 2147935958 -4964 1006704 C ATOM 10607 NHl ARG C 422 -9010 52855 6193 10011965 C

ATOM 10523 O ASP C 411 22505 36119 4307 1007122 C ATOM 10608 NH2 ARG C 422 -8793 53537 4013 10011965 C

ATOM 10524 N ALA C 412 2052635090 -4637 1008003 C ATOM 10609 C ARG C 422 -6177 48233 8267 1008238 C

ATOM 10525 CA ALA C 412 20592 34252 -3446 1009305 C ATOM 10610 O ARG C 422 -713047582 8682 1007305 C

ATOM 10526 CB ALA C 412 20458 35105 -2197 1007555 C ATOM 10611 N THR C 423 -550649076 9043 10011345 C

ATOM 10527 C ALA C 412 1948233206 -3481 1008775 C ATOM 10612 CA THR C 423 -586649255 10449 10012310 C

ATOM 10528 O ALA C 412 1860833240 -4348 1008280 C ATOM 10613 CB THR C 423 -4765 50026 11226 10017180 C

ATOM 10529 N ASN C 413 1951732282 -2527 1008056 C ATOM 10614 OGl THR C 423 -3515 49346 11089 10012759 C

ATOM 10530 CA ASN C 413 18521 31220 -2460 1007337 C ATOM 10615 CG2 THR C 423 -5108 50115 12713 10012759 C

ATOM 10531 CB ASN C 413 19137 29947 -1884 1006343 C ATOM 10616 C THR C 423 -7178 50010 10618 10012132 C

ATOM 10532 CG ASN C 413 2026629412 -2734 1006343 C ATOM 10617 O THR C 423 -7192 51109 11162 10011981 C

ATOM 10533 ODl ASN C 413 20181 29393 -3965 1006343 C ATOM 10618 N THR C 424 8282 49429 10157 10016475 C

ATOM 10534 ND2 ASN C 413 21328 28958 -2081 1006343 C ATOM 10619 CA THR C 424 -9579 50085 10295 10016475 C

ATOM 10535 C ASN C 413 17353 31621 -1594 1007795 C ATOM 10620 CB THR C 424 -10695 49282 9603 10018634 C

ATOM 10536 O ASN C 413 1629830997 -1631 1007764 C ATOM 10621 OGl THR C 424 -1036249105 8221 10013215 C

ATOM 10537 N THR C 414 17553 32680 -0827 1005390 C ATOM 10622 CG2 THR C 424 -12028 50019 9705 10013215 C

ATOM 10538 CA THR C 414 16557 33166 0104 1005694 C ATOM 10623 C THR C 424 -9903 50219 11778 10016475 C

ATOM 10539 CB THR C 414 1726933962 1199 10010249 C ATOM 10624 O THR C 424 -939449457 12601 10016475 C

ATOM 10540 OGl THR C 414 16306 34456 2119 1007298 C ATOM 10625 N SER C 425 -10748 51186 12116 10015338 C

ATOM 10541 CG2 THR C 414 18055 35114 0613 1007298 C ATOM 10626 CA SER C 425 -11114 51422 13507 10015338 C

ATOM 10542 C THRC414 15415 33981 0519 1005640 C ATOM 10627 CB SER C 425 -11758 52800 13647 10018367 C ATOM 10543 O THR C 414 1550534397 -1672 1005747 C ATOM 10628 OG SER C 425 -11996 53102 15009 1007961 C

ATOM 10544 N TYRC415 1433234179 0236 1004477 C ATOM 10629 C SER C 425 -12043 50361 14100 10015338 C

ATOM 10545 CA TYR C 415 13155 34933 -0231 1004580 C ATOM 10630 O SER C 425 -12408 50437 15273 10015338 C

ATOM 10546 CB TYR C 415 11942 34020 -0414 1008090 C ATOM 10631 N LYS C 426 -12422 49374 13294 10017645 C

ATOM 10547 CG TYR C 415 12082 33004 -1508 1004784 C ATOM 10632 CA LYS C 426 -1330848305 13754 10017645 C

ATOM 10548 CDl TYR C 415 12977 31944 1390 1004784 C ATOM 10633 CB LYS C 426 -1354047296 12631 10018296 C

ATOM 10549 CE1TYRC415 1312631011 -2408 1004784 C ATOM 10634 CG LYS C 426 13982 47910 11321 10012726 C

ATOM 10550 CD2TYRC415 11332 33108 -2673 1004784 C ATOM 10635 CD LYS C 426 -14001 46861 10229 10012726 C

ATOM 10551 CE2TYRC415 11469 32181 -3703 1004784 C ATOM 10636 CE LYS C 426 -14303 47472 8876 10012726 C

ATOM 10552 CZ TYR C 415 1237031132 -3564 1004784 C ATOM 10637 NZ LYS C 426 -14282 46439 7803 10012726 C

ATOM 10553 OH TYRC415 12520 30193 -4567 1004784 C ATOM 10638 C LYS C 426 -1272047575 14959 10017645 C ATOM 10554 C TYRC415 12753 36015 0764 1005336 C ATOM 10639 O LYS C 426 -13438 47215 15891 10017645 C

ATOM 10555 O TYRC415 1316035977 1931 1004801 C ATOM 10640 N MET C 427 -11408 47359 14927 10016625 C

ATOM 10556 N SERC416 11936 36965 0307 1004413 C ATOM 10641 CA MET C 427 -10700 46663 15999 10016625

ATOM 10557 CA SERC416 11481 38053 1168 1004208 C C

ATOM 10558 CB SER C 416 1224639346 0867 1007672 C ATOM 10642 CB MET C 427 -925646386 15574 10014692 C

ATOM 10559 OG SERC 416 1357439282 1369 1005310 C ATOM 10643 CG MET C 427 -8510 47614 15080 10014692 C

ATOM 10560 C SER C 416 9993 38266 0984 1004827 C ATOM 10644 SD METC 427 684247217 14540 10014692 C

ATOM 10561 O SER C 416 9445 37990 -0084 1004664 C ATOM 10645 CE MET C 427 -715946496 12927 10014692 C 65251/C766

ATOM 10646 C MET C 427 -1070447423 17320 10016625 C ATOM 10731 O ASPC438 11405 26481 11804 1005848 C

ATOM 10647 O MET C 427 -11519 48320 17530 10016625 C ATOM 10732 N THRC439 1210428173 10520 1007701 C

ATOM 10648 N SER C 428 -978647054 18208 10012519 C ATOM 10733 CA THR C 439 13015 28682 11537 1007436 C

ATOM 10649 CA SER C 428 -969247694 19512 10012684 C ATOM 10734 CB THR C 439 1407729600 10899 1006456 C

ATOM 10650 CB SER C 428 10922 47343 20350 10011910 C ATOM 10735 OGl THR C 439 13445 30738 10299 1005037 C

ATOM 10651 OG SER C 428 -10991 45947 20581 10011581 C ATOM 10736 CG2THRC439 14825 28847 9804 1005037 C

ATOM 10652 C SER C 428 -8433 4729420280 10012279 C ATOM 10737 C THR C 439 1202729473 12393 1008013 C

ATOM 10653 O SER C 428 -844847252 21509 10012267 C ATOM 10738 O THR C 439 11072 30020 11859 1008047 C

ATOM 10654 N SER C 429 -734847002 19568 10013725 C ATOM 10739 N LEUC440 1222229533 13702 1007088 C

ATOM 10655 CA SER C 429 -610046611 20223 10013592 C ATOM 10740 CA LEU C 440 11267 30231 14583 1007290 C

ATOM 10656 CB SER C 429 -6165 45148 20679 10011780 C ATOM 10741 CB LEUC440 11334 31778 14420 1006894 C

ATOM 10657 OG SER C 429 -715644949 21667 10011780 C ATOM 10742 CG LEU C 440 11069 32776 13254 1004894 C

ATOM 10658 C SER C 429 -4880 46776 19330 10013430 C ATOM 10743 CDl LEUC440 12135 32637 12210 1004894 C

ATOM 10659 O SER C 429 -3751 46650 19793 10012300 C ATOM 10744 CD2LEUC440 9691 32622 12635 1004894 C

ATOM 10660 N GLN C 430 -510547064 18056 1006991 C ATOM 10745 C LEU C 440 9821 29747 14379 1008285 C

ATOM 10661 CA GLN C 430 -4012 47201 17096 1006991 C ATOM 10746 0 LEU C 440 9016 30437 13763 1008107 C

ATOM 10662 CB GLN C 430 -298748231 17553 10017823 C ATOM 10747 N GLUC441 949828561 14905 1005836 C

ATOM 10663 CG GLN C 430 -1887 48424 16534 10010722 C ATOM 10748 CA GLUC441 8156 27964 14779 1005836 C

ATOM 10664 CD GLN C 430 -0832 49402 16986 10010722 C ATOM 10749 CB GLU C 441 788627021 15949 10018794 C

ATOM 10665 OE 1 GLN C 430 -006449125 17906 10010722 C ATOM 10750 CG GLU C 441 879725809 15975 10011130 C

ATOM 10666 NE2GLNC430 -0789 50561 16342 10010722 C ATOM 10751 CD GLU C 441 840024805 17043 10011130 C

ATOM 10667 C GLN C 430 -333645841 16951 1006991 C ATOM 10752 OEl GLU C 441 835425189 18234 10011130 C

ATOM 10668 O GLN C 430 -2661 45362 17861 1006991 C ATOM 10753 OE2GLUC441 8132 23630 16692 10011130 C

ATOM 10669 N PRO C 431 -3491 45210 15784 1007511 C ATOM 10754 C GLUC441 7015 28975 14665 1005836 C

ATOM 10670 CD PRO C 431 -394845770 14502 1005879 C ATOM 10755 O GLU C 441 6115 28819 13839 1005836 C

ATOM 10671 CA PRO C 431 -288643901 15579 1007510 C ATOM 10756 N ALA C 442 705030011 15493 1007233 C

ATOM 10672 CB PRO C 431 -330043558 14154 10015775 C ATOM 10757 CA ALA C 442 6029 31050 15437 1007055 C

ATOM 10673 CG PRO C 431 -326044876 13492 10012831 C ATOM 10758 CB ALA C 442 4673 30477 15810 1002309 C

ATOM 10674 C PRO C 431 -138743872 15765 1007172 C ATOM 10759 C ALAC442 6397 32192 16371 1006654 C

ATOM 10675 O PRO C 431 -070644S97 15701 1007160 C ATOM 107600 ALAC442 6315 32044 17588 1006395 C

ATOM 10676 N VAL C 432 -089742670 16020 1006225 C ATOM 10761 N GLN C 443 6816 33322 15799 1005040 C

ATOM 10677 CA VAL C 432 0512 42409 16181 1006463 C ATOM 10762 CA GLN C 443 7193 34499 16585 1005368 C

ATOM 10678 CB VAL C 432 079741829 17564 1008655 C ATOM 10763 CB GLN C 443 8610 34952 16244 1009989 C

ATOM 10679 CGl VAL C 432 0053 40537 17755 1005863 C ATOM 10764 CG GLN C 443 966934301 17091 1008312 C

ATOM 10680 CG2 VAL C 432 2251 41607 17719 1005863 C ATOM 10765 CD GLN C 443 10956 35090 17090 1008312 C

ATOM 10681 C VAL C 432 0761 41372 15087 1006263 C ATOM 10766 OEl GLN C 443 10952 36300 17332 1008312 C

ATOM 10682 O VAL C 432 -014740622 14723 1005299 C ATOM 10767 NE2 GLN C 443 12073 34412 16823 1008312 C

ATOM 10683 N CYS C 433 1964 41327 14536 1006685 C ATOM 10768 C GLNC443 6241 35677 16421 1005585 C

ATOM 10684 CA CYS C 433 222640376 13470 1006273 C ATOM 10769 O GLN C 443 5629 35860 15374 1005691 C

ATOM 10685 C CYS C 433 282539062 13974 1006037 C ATOM 10770 N VAL C 444 6120 36473 17475 1006896 C

ATOM 10686 O CYS C 433 3862 39067 14639 1006111 C ATOM 10771 CA VAL C 444 5244 37635 17456 1006611 C

ATOM 10687 CB CYS C 433 315441012 12426 10012859 C ATOM 10772 CB VALC 444 4411 37715 18754 1006375 C

ATOM 10688 SG CYS C 433 341840001 10932 1007570 C ATOM 10773 CGl VAL C 444 3261 38670 18568 1005605 C

ATOM 10689 N VAL C 434 2162 37941 13673 1005806 C ATOM 10774 CG2 VAL C 444 3893 36340 19127 1005605 C

ATOM 10690 CA VAL C 434 2670 36626 14056 1005405 C ATOM 10775 C VAL C 444 6085 38905 17307 1006993 C

ATOM 10691 CB VAL C 434 159035745 14685 1006463 C ATOM 10776 O VAL C 444 7172 39011 17876 1007219 C

ATOM 10692 CGl VAL C 434 2236 34486 15247 1004641 C ATOM 10777 N TYR C 445 559039857 16522 1004849 C

ATOM 10693 CG2 VAL C 434 0869 36504 15781 1004641 C ATOM 10778 CA TYRC445 6291 41117 16286 1004756 C

ATOM 10694 C VAL C 434 3182 35927 12798 1006445 C ATOM 10779 CB TYRC445 693941097 14914 1007824 C

ATOM 10695 O VAL C 434 2415 35650 11881 1005551 C ATOM 10780 CG TYR C 445 792839976 14758 1005066 C

ATOM 10696 N VAL C 435 4476 35635 12768 1004992 C ATOM 10781 CDl TYR C 445 7540 38736 14256 1005066 C

ATOM 10697 CA VAL C 435 5107 35012 11615 1004166 C ATOM 10782 CE1TYRC445 8459 37699 14106 1005066 C

ATOM 10698 CB VAL C 435 6441 35723 11305 1005635 C ATOM 10783 CD2TYRC445 925840150 15112 1005066 C

ATOM 10699 CGl VAL C 435 7230 34960 10259 1003568 C ATOM 10784 CE2TYRC445 10181 39122 14968 1005066 C

ATOM 10700 CG2 VAL C 435 6160 37128 10840 1003568 C ATOM 10785 CZ TYRC445 978037897 14463 1005066 C

ATOM 10701 C VAL C 435 5375 33518 11770 10O4958 C ATOM 10786 OH TYRC 445 10711 36882 14302 1005066 C

ATOM 10702 O VAL C 435 6077 33098 12684 1005017 C ATOM 10787 C TYR C 445 531442280 16396 1004902 C

ATOM 10703 N PHE C 436 4827 32719 10861 1005943 C ATOM 10788 O TYR C 445 419542210 15884 1005188 C

ATOM 10704 CA PHE C 436 502631281 10899 1005563 C ATOM 10789 N THR C 446 574543359 17048 1004985 C

ATOM 10705 CB PHE C 436 370430551 10684 1006247 C ATOM 10790 CA THR C 446 4871 44512 17266 1005683 C

ATOM 10706 CG PHE C 436 269730794 11763 1003724 C ATOM 10791 CB THR C 446 470044750 18767 1007369 C

ATOM 10707 CDl PHE C 436 186831905 11726 1003724 C ATOM 10792 OGl THR C 446 599444939 19355 1006184 C

ATOM 10708 CD2 PHE C 436 2591 29917 12841 1003724 C ATOM 10793 CG2THRC446 4031 43560 19424 1006184 C

ATOM 10709 CEl PHE C 436 0941 32141 12749 1003724 C ATOM 10794 C THR C 446 525445860 16652 1006663 C

ATOM 10710 CE2 PHE C 436 1668 30147 13869 1003724 C ATOM 10795 O THR C 446 598045943 15661 1007030 C

ATOM 10711 CZ PHE C 436 0843 31256 13823 1003724 C ATOM 10796 N CYS C 447 4713 46898 17292 1008716 C

ATOM 10712 C PHE C 436 6019 30854 9830 1006346 C ATOM 10797 CA CYS C 447 487948328 16997 1008814 C

ATOM 10713 O PHE C 436 5792 31067 8639 1006284 C ATOM 10798 C CYS C 447 438048932 15681 1008817 C

ATOM 10714 N HIS C 437 7121 30246 10258 1004166 C ATOM 10799 O CYS C 447 4495 48346 14604 1008503 C

ATOM 10715 CA HIS C 437 815729798 9339 1004273 C ATOM 10800 CB CYS C 447 6333 48771 17247 10013566 C

ATOM 10716 CB HIS C 437 911430950 9033 1007291 C ATOM 10801 SG CYS C 447 763747967 16267 10012119 C

ATOM 10717 CG HIS C 437 10202 30588 8076 1004928 C ATOM 10802 N SER C 448 3811 50129 15813 10020084 C

ATOM 10718 CD2 HIS C 437 1148630214 8286 1004928 C ATOM 10803 CA SER C 448 3271 50896 14696 10020084 C

ATOM 10719 NDl HIS C 437 1000630536 6714 1004928 C ATOM 10804 CB SER C 448 1751 51002 14812 I 0020084 C

ATOM 10720 CEl HIS C 437 11123 30147 6125 1004928 C ATOM 10805 OG SERC448 1155 49718 14819 10020084 C

ATOM 10721 NE2 HIS C 437 1203629942 7057 1004928 C ATOM 10806 C SER C 448 3890 52294 14702 10020084 C

ATOM 10722 C HIS C 437 8926 28643 9978 1004704 C ATOM 10807 O SER C 448 4988 52481 15226 10020084 C

ATOM 10723 O HIS C 437 8905 28485 11195 1004926 C ATOM 10808 N GLU C 449 317953275 14145 10012203 C

ATOM 10724 N ASP C 438 9601 27836 9163 1005167 C ATOM 10809 CA GLU C 449 3692 54640 14057 10012203 C

ATOM 10725 CA ASP C 438 10363 26700 9672 1005358 C ATOM 10810 CB GLU C 449 420055129 15416 10011772 C

ATOM 10726 CB ASP C 438 11085 25996 8529 10010511 C ATOM 10811 CG GLU C 449 3117 55617 16353 10011772 C

ATOM 10727 CG ASP C 438 1018925007 7815 1007607 C ATOM 10812 CD GLU C 449 1941 54668 16419 10011772 C

ATOM 10728 ODl ASP C 438 894825171 7903 1007607 C ATOM 10813 OEl GLU C 449 216053475 16708 10011772 C

ATOM 10729 OD2 ASP C 438 10719 24074 7166 1007607 C ATOM 10814 OE2GLUC449 079755113 16181 10011772 C

ATOM 10730 C ASP C 438 1133727117 10760 1005492 C ATOM 10815 C GLUC449 484754596 13075 10012203 C 65251/C766

ATOM 10816 O GLU C 449 498955457 12212 10012203 C ATOM 10901 CEl HISD 10 54113 9344-39037 1003717 D ATOM 10817 N GLY C 450 5661 53561 13221 1006264 C ATOM 10902 NE2 HIS D 10 53503 10084-39943 1003465 D ATOM 10818 CA GLY C 450 6817 53348 12376 1006264 C ATOM 10903 C HISD 10 56330 8655-43181 1003484 D ATOM 10819 C GLY C 450 7845 52665 13247 1006264 C ATOM 10904 0 HISD 10 55984 9651 -43807 1003300 D ATOM 10820 O GLY C 450 9013 52534 12877 1006264 C ATOM 10905 N VALD 1) 55950 7437-43518 1003699 D ATOM 10821 N CYS C 451 7388 52225 14416 10018556 C ATOM 10906 CA VALD 11 55057 7234-44646 1003957 D ATOM 10822 CA CYS C 451 824051571 15395 10018556 C ATOM 10907 CB VALD 11 55516 6047 45513 1003192 D ATOM 10823 CB CYS C 451 8862 50311 14821 10019059 C ATOM 10908 CGl VALD 11 56892 6352-46060 1002798 D ATOM 10824 SG CYS C 451 7643 49011 14532 10019059 C ATOM 10909 CG2 VALD 11 55522 4759-44695 1003390 D ATOM 10825 C CYS C 451 9336 52521 15788 10018556 C ATOM 10910 C VALD 11 53634 7018-44158 1003818 D ATOM 10826 O CYS C 451 10513 52134 15640 10018556 C ATOM 10911 O VALD 11 53394 6554-43040 1003519 D ATOM 10827 OXT CYS C 451 8992 53637 16230 10016296 C ATOM 10912 N VALD 12 52689 7360-45013 1003762 D ATOM 10828 CB ARGD 1 65351 23727-44290 10014545 D ATOM 10913 CA VALD 12 51304 7262-44641 1003579 D ATOM 10829 CG ARGD 1 5421922825-44813 10014545 D ATOM 10914 CB VALD 12 50733 8668-44550 1004843 D ATOM 10830 CD ARGD 1 6396622951 -46321 10014545 D ATOM 10915 CGl VALD 12 50554 9239-45947 1004223 D ATOM 10831 NE ARGD 1 6471721977-47118 10014545 D ATOM 10916 CG2 VALD 12 49444 8651-43770 1005190 D ATOM 10832 CZ ARGD 1 6453820658 -47067 10014545 D ATOM 10917 C VALD 12 50552 6417-45660 1003375 D ATOM 10833 NHl ARG D 1 6363020132 -46255 10014545 D ATOM 10918 O VALD 12 51033 6217-46780 1003359 D ATOM 10834 NH2ARGD 1 65275 19858-47827 10014545 D ATOM 10919 N ALA D 13 49381 5916-45266 1004410 D ATOM 10835 C ARGD 1 67140 21998 -44719 10020084 D ATOM 10920 CA ALA D 13 48574 5056-46141 1004377 D ATOM 10836 O ARGD 1 66615 21129^5416 10020084 D ATOM 10921 CB ALAD 13 47522 4308-45319 1002447 D ATOM 10837 N ARGD 1 66780 23889 -46310 10020084 D ATOM 10922 C ALAD 13 47896 5791 -47277 1004775 D ATOM 10838 CA ARGD 1 6675023474 -44878 10020084 D ATOM 10923 O ALAD 13 47396 6891 -47102 1004526 D ATOM 10839 N THRD 2 68069 21722 -43807 10020084 D ATOM 10924 N ASND 14 47883 5161 -48441 1004532 D ATOM 10840 CA THRD 2 6853320353 -43562 10020084 D ATOM 10925 CA ASND 14 47252 5719-49632 1004644 D ATOM 10841 CB THRD 2 6988720339-42792 10011636 D ATOM 10926 CB ASND 14 47849 5066 50869 1004259 D ATOM 10842 OGl THRD 2 70865 21099-43511 10011510 D ATOM 10927 CG ASND 14 47245 5586-52159 1004458 D ATOM 10843 CG2THRD 2 70390 18908-42614 10011825 D ATOM 10928 ODlASND 14 47578 5089-53242 1004416 D ATOM 10844 C THRD 2 67529 19565-42723 10020084 D ATOM 10929 ND2 ASN D 14 46364 6590-52059 1004670 D ATOM 10845 O THRD 2 67354 19855-41538 10020084 D ATOM 10930 C ASND 14 45750 5438^19607 1004932 D ATOM 10846 N PROD 3 66845 18568-43319 10020084 D ATOM 10931 O ASND 14 45343 4285-49693 1004984 D ATOM 10847 CD PROD 3 66759 18106-44718 1009256 D ATOM 10932 N PROD 15 44909 6484-49517 1005970 D ATOM 10848 CA PROD 3 65905 17836 -42469 10020084 D ATOM 10933 CD PROD 15 45227 7918-49448 1003807 D ATOM 10849 CB PROD 3 65552 16621 -43323 1009080 D ATOM 10934 CA PROD 15 43458 6287-49483 1006330 D ATOM 10850 CG PROD 3 65507 17219-44696 1009067 D ATOM 10935 CB PROD 15 42927 7547-49024 1004241 D ATOM 10851 C PROD 3 66618 17484-41161 10020084 D ATOM 10936 CG PROD 15 44145 8414-48554 1004068 D ATOM 10852 O PROD 3 66003 17483 -40092 10020084 D ATOM 10937 C PROD 15 42887 5905-50846 1005451 D ATOM 10853 N SERD 4 67923 17214-41265 10012346 D ATOM 10938 O PROD 15 41805 5335-50938 1006654 D ATOM 10854 CA SERD 4 68770 16900-40110 10012003 D ATOM 10939 N GLND 16 43621 6227-51901 1008435 D ATOM 10855 CB SERD 4 68010 16078-39059 10014398 D ATOM 10940 CA GLND 16 43186 5936-53255 1008330 D ATOM 10856 OG SERD 4 68001 14698-39382 10014593 D ATOM 10941 CB GLND 16 43941 6843-54230 10011494 D ATOM 10857 C SERD 4 70053 16154-40459 10012037 D ATOM 10942 CG GLND 16 43289 7019-55591 10011787 D ATOM 10858 O SERD 4 71067 16342-39789 10012052 D ATOM 10943 CD GLND 16 41896 7615-55493 10011966 D ATOM 10859 N ASPD 5 70000 15319 41499 1006491 D ATOM 10944 OEl GLN D 16 41667 8550-54728 10012178 D ATOM 10860 CA ASPD 5 71136 14492-41941 1006502 D ATOM 10945 NE2 GLN D 16 40960 7080 56277 10011831 D ATOM 10861 CB ASPD 5 72435 14984-41293 10017108 D ATOM 10946 C GLND 16 43403 4461 -53631 1007997 D ATOM 10862 CG ASPD 5 73630 14141 -41656 10017108 D ATOM 10947 O GLND 16 43140 4056-54767 1008054 D ATOM 10863 ODl ASP D 5 74698 14350 41044 10017108 D ATOM 10948 N ALAD 17 43882 3654-52688 1007304 D ATOM 10864 OD2ASPD 5 73512 13278-42549 10016964 D ATOM 10949 CA ALAD 17 44119 2237-52960 1007680 D ATOM 10865 C ASPD 5 70877 13014-41560 1006252 D ATOM 10950 CB ALAD 17 45590 1898-52760 1005204 D ATOM 10866 O ASPD 5 71426 12092-42172 1006603 D ATOM 10951 C ALAD 17 43258 1370-52057 1008130 D ATOM 10867 N LYSD 6 70026 12809 -40552 1005825 D ATOM 10952 0 ALAD 17 43771 0618-51229 1008294 D ATOM 10868 CA LYSD 6 69657 11480 -40062 1005463 D ATOM 10953 N GLUD 18 41944 1481-52227 1007932 D ATOM 10869 CB LYSD 6 68923 11584 -38728 1005550 D ATOM 10954 CA GLUD 18 40993 0719-51428 1008132 D ATOM 10870 CG LYSD 6 69704 12000-37516 1006191 D ATOM 10955 CB GLUD 18 39584 0887-51992 10012242 D ATOM 10871 CD LYSD 6 68727 12153-36350 1006552 D ATOM 10956 CG GLUD 18 39437 0386-53421 10012242 D ATOM 10872 CE LYSD 6 69443 12365 35037 1006879 D ATOM 10957 CD GLUD 18 38001 0430-53912 10012242 D ATOM 10873 NZ LYSD 6 70252 11 165-34670 1006998 D ATOM 10958 OEl GLUD 18 37146 -0246-53302 10012242 D ATOM 10874 C LYSD 6 68698 10738-40991 1004996 D ATOM 10959 OE2 GLU D 18 37726 1138-54906 10012242 D ATOM 10875 O LYSD 6 67702 11311 -41451 1005384 D ATOM 10960 C GLUD 18 41331 -0768-51361 1008098 D ATOM 10876 N PROD 7 68978 9459 -41291 1004427 D ATOM 10961 O GLUD 18 41896 -1337-52301 1008059 D ATOM 10877 CD PROD 7 70189 8650-41119 1003417 D ATOM 10962 N GLYD 19 40986 -1381 -50233 1007479 D ATOM 10878 CA PROD 7 68016 8772-42161 1004231 D ATOM 10963 CA GLYD 19 41227 -2797-50050 1007228 D ATOM 10879 CB PROD 7 68622 7376-42348 1003617 D ATOM 10964 C GLYD 19 42643 3223^19708 1007078 D ATOM 10880 CG PROD 7 69621 7255-41228 1003504 D ATOM 10965 O GLYD 19 42871 -4391 -49398 1007079 D ATOM 10881 C PROD 7 66696 8730 -41398 1004037 D ATOM 10966 N GLN D 20 43599 -2302-49759 1007044 D ATOM 10882 O PROD 7 66666 8417-40202 1004138 D ATOM 10967 CA GLND 20 44982 -2646-49443 1006601 D ATOM 10883 N VALD 8 65610 9060-42092 1003108 D ATOM 10968 CB GLND 20 45741 -2940-50725 1008933 D ATOM 10884 CA VALD 8 64304 9107-41459 1003224 D ATOM 10969 CG GLND 20 45638 -I 827-51738 1009031 D ATOM 10885 CB VALD 8 64085 10512-40770 1002808 D ATOM 10970 CD GLND 20 46340 -2165-53029 1009007 D ATOM 10886 CGlVALD 8 64222 Il 625 -41787 1002866 D ATOM 10971 OEl GLND 20 46001 -3145-53687 1008972 D ATOM 10887 CG2VALD 8 62726 10579-40108 1003078 D ATOM 10972 NE2 GLN D 20 47328 -1356-53400 1008952 D ATOM 10888 C VALD 8 63209 8880 -42479 1003474 D ATOM 10973 C GLN D 20 45694 -1553-48656 1006075 D ATOM 10889 O VALD 8 63418 9074-43680 1003398 D ATOM 109740 GLN D 20 45182 -0447 ^8503 1005946 D ATOM 10890 N ALAD 9 62038 8485 -41994 1003459 D ATOM 10975 N LEUD 21 46877 -1871 -48150 1005120 D ATOM 10891 CA ALAD 9 60909 8279 -42873 1004083 D ATOM 10976 CA LEUD 21 47648 -0912-47367 1004766 D ATOM 10892 CB ALAD 9 61101 7027-43683 1003249 D ATOM 10977 CB LEUD 21 47969 -1497-45985 1004613 D ATOM 10893 C ALAD 9 59635 8183-42089 1004181 D ATOM 10978 CG LEUD 21 48855 -0686-45036 1004491 D ATOM 10894 O ALAD 9 59598 7568 -41027 1003979 D ATOM 10979 CDl LEUD 21 48365 0734-44960 1004221 D ATOM 10895 N HISD 10 58595 8821-42606 1003576 D ATOM 10980 CD2 LEU D 21 48850 -1337-43654 1004695 D ATOM 10896 CA HISD 10 57274 8758-41998 1003663 D ATOM 10981 C LEUD 21 48929 -0560-48093 1004627 D ATOM 10897 CB HIS D 10 56955 10011-41197 1003519 D ATOM 10982 0 LEUD 21 49936 -1234-47959 1004159 D ATOM 10898 CG HISD 10 55617 9959^10527 1003668 D ATOM 10983 N GLN D 22 48887 0505-48869 1003753 D ATOM 10899 CD2HISD 10 54421 10482-40885 1003441 D ATOM 10984 CA GLND 22 50044 0938-49642 1004213 D ATOM 10900 NDl HISD 10 55391 9254-39366 1003682 D ATOM 10985 CB GLN D 22 49607 1152-51094 1006941 D 65251/C766

ATOM 10986 CG GLND 22 50637 1773-52000 1007618 D ATOM 11071 CA LEU D 32 61450 976746821 1003931 D ATOM 10987 CD GLN D 22 50031 2243-53301 1008240 D ATOM 11072 CB LEU D 32 60734 9220 -48052 1003401 D

ATOM 1098S OEl GLN D 22 50693 2888-54108 1008763 D ATOM 11073 CG LEU D 32 61471 800948617 1003259 D

ATOM 10989 NE2 GLN D 22 48759 1921-53511 1008316 D ATOM 11074 CDl LEU D 32 61405 685847608 1003157 D

ATOM 10990 C GLND 22 50616 2226-49048 1003952 D ATOM 11075 CD2 LEU D 32 60857 760449937 1003291 D

ATOM 10991 O GLN D 22 49901 3216-48876 1003847 D ATOM 11076 C LEUD 32 62779 1041547223 1003895 D

ATOM 10992 N TRP D 23 51903 2223 -48740 1004405 D ATOM 11077 O LEU D 32 62968 1081148377 1004482 D

ATOM 10993 CA TRPD 23 52529 3397-48143 1003793 D ATOM 11078 N ALAD 33 63701 1052846269 1004046 D

ATOM 10994 CB TRP D 23 53708 2976 -47256 1003793 D ATOM 11079 CA ALA D 33 64962 U 19446556 1004098 D

ATOM 10995 CG TRPD 23 53372 196846212 1003845 D ATOM 11080 CB ALA D 33 64901 12618-46059 1004057 D ATOM 10996 CD2 TRP D 23 52571 2177-45036 1003656 D ATOM 11081 C ALAD 33 66241 1057946051 1004277 D

ATOM 10997 CE2 TRP D 23 52555 0959-44324 1003818 D ATOM 11082 O ALAD 33 66254 961945282 1004695 D

ATOM 10998 CE3 TRP D 23 51868 327544516 1003625 D ATOM 11083 N ASN D 34 67331 11189-46499 1004540 D

ATOM 10999 CDl TRP D 23 53787 0681 -46169 1003792 D ATOM 11084 CA ASN D 34 68670 1079846118 1004259 D

ATOM 11000 NElTRPD 23 53304 0063-45036 1003701 D ATOM 11085 CB ASN D 34 68918 1122244684 1004405 D

ATOM 11001 CZ2TRPD 23 51870 0806-43123 1004024 D ATOM 11086 CG ASN D 34 68764 12699-44513 1004797 D

ATOM 11002 CZ3 TRP D 23 51186 3123-43319 1004069 D ATOM 11087 ODl ASN D 34 69325 1346745293 1005045 D

ATOM 11003 CH2TRPD 23 51195 1896-42637 1003850 D ATOM 11088 ND2 ASN D 34 67995 1311743506 1004338 D

ATOM 11004 C TRPD 23 53050 4416 49147 1003843 D ATOM 11089 C ASN D 34 69015 933946298 1004334 D

ATOM 11005 O TRPD 23 53653 4044-50153 1003971 D ATOM 11090 O ASN D 34 69656 8731-45441 1004588 D

ATOM 11006 N LEU D 24 52823 5700-48874 1003751 D ATOM 11091 N GLY D 35 68587 877247417 1004594 D ATOM 11007 CA LEUD 24 53342 6748 49744 1003520 D ATOM 11092 CA GLY D 35 68937 7399-47691 1004053 D

ATOM 11008 CB LEUD 24 52250 7457-50540 1005762 D ATOM 11093 C GLY D 35 67890 632047565 1004088 D

ATOM 11009 CG LEUD 24 50869 6865-50709 1005835 D ATOM 11094 O GLYD 35 67940 5358 -48307 1004237 D

ATOM 11010 CDl LEUD 24 50141 7006-49401 1005997 D ATOM 11095 N VALD 36 66950 6431-46643 1002989 D

ATOM 11011 CD2LEUD 24 50120 7609-51791 1005346 D ATOM 11096 CA VAL D 36 65993 535146561 1003122 D

ATOM 11012 C LEUD 24 54049 7789-48914 1004206 D ATOM 11097 CB VALD 36 65148 541045240 1002838 D

ATOM 11013 O LEU D 24 53798 7919-47723 1003904 D ATOM 11098 CGl VALD 36 65430 666444512 1002641 D

ATOM 11014 N ASN D 25 54927 8539-49559 1003531 D ATOM 11099 CG2 VAL D 36 63681 524745524 1002878 D

ATOM 11015 CA ASND 25 55670 9585-48885 1003675 D ATOM 11100 C VALD 36 65137 5357-47824 1003537 D

ATOM 11016 CB ASND 25 57161 9271 -48939 1003628 D ATOM 11101 O VAL D 36 64779 641048347 1003633 D

ATOM 11017 CG ASND 25 57721 9444-50316 1003785 D ATOM 11102 N GLU D 37 64848 416248329 1004160 D ATOM 11018 ODl ASND 25 58529 10338-50555 1004184 D ATOM 11103 CA GLU D 37 64068 4015-49543 1004420 D

ATOM 11019 ND2 ASN D 25 57275 8601-51249 1003425 D ATOM 11104 CB GLU D 37 64875 3258 -50598 1006374 D

ATOM 11020 C ASND 25 55417 10918-49580 1003728 D ATOM 11105 CG GLU D 37 66346 3634 -50603 1007077 D

ATOM 11021 O ASND 25 55911 11951-49145 1003964 D ATOM 11106 CD GLU D 37 67223 2639-51356 1007374 D

ATOM 11022 N ARGD 26 54648 10900-50660 1003845 D ATOM 11107 OEl GLU D 37 66861 1434-51413 1007717 D

ATOM 11023 CA ARGD 26 54375 12122-51404 1003973 D ATOM 11108 OE2 GLU D 37 68287 3061 -51870 1007430 D

ATOM 11024 CB ARG D 26 54153 11792 -52879 1003913 D ATOM 11109 C GLU D 37 62789 3260 -49251 1004309 D

ATOM 11025 CG ARGD 26 53065 10768-53136 1004004 D ATOM 11110 O GLU D 37 62699 2489 -48292 1004555 D

ATOM 11026 CD ARGD 26 52735 10716-54618 1004410 D ATOM 11111 N LEU D 38 61788 3516-50077 1005021 D

ATOM 11027 NE ARG D 26 51705 9731 -54938 1004524 D ATOM 11112 CA LEU D 38 60505 284649957 1005225 D

ATOM 11028 CZ ARGD 26 51942 8441 55105 1004580 D ATOM 11113 CB LEUD 38 59375 3868 -49999 1003858 D

ATOM 11029 NHl ARGD 26 53176 7976 54983 1004628 D ATOM 11114 CG LEU D 38 57973 331649791 1003649 D

ATOM 11030 NH2 ARGD 26 50949 7626-55403 1004483 D ATOM 11115 CDl LEU D 38 57963 238948597 1003487 D

ATOM 11031 C ARGD 26 53183 12928-50888 1003779 D ATOM 11116 CD2LEUD 38 56985 448249610 1003336 D

ATOM 11032 O ARGD 26 52355 13391 -51673 1003750 D ATOM 11117 C LEU D 38 60490 1951 -51184 1005252 D

ATOM 11033 N ARGD 27 53104 13113-49575 1003788 D ATOM 11118 O LEU D 38 60279 2404 52300 1004613 D

ATOM 11034 CA ARG D 27 51997 13842-49001 1003881 D ATOM 11119 N ARG D 39 60753 0673 -50969 1004383 D

ATOM 11035 CB ARGD 27 51026 12865 -48342 1003370 D ATOM 11120 CA ARG D 39 60834 -0292 -52057 1005036 D

ATOM 11036 CG ARG D 27 50303 11985 -49335 1003512 D ATOM 11121 CB ARGD 39 62277 -0783 52153 1005568 D

ATOM 11037 CD ARG D 27 49671 12831 -50428 1003749 D ATOM 11122 CG ARG D 39 62608 -1601 -53351 1006338 D

ATOM 11038 NE ARGD 27 49074 12036-51489 1004088 D ATOM 11123 CD ARG D 39 64107 -1788 -53433 1007199 D

ATOM 11039 CZ ARGD 27 48044 11226-51297 1004449 D ATOM 11124 NE ARG D 39 64499 2300 -54742 1007852 D

ATOM 11040 NHl ARGD 27 47552 10533-52323 1004536 D ATOM 11125 CZ ARG D 39 65753 -2332-55190 1007932 D

ATOM 11041 NH2ARGD 27 47509 11117-50072 1004272 D ATOM 11126 NHl ARG D 39 66742 -1881 -54425 1007780 D

ATOM 11042 C ARGD 27 52398 14920-48008 1003927 D ATOM 11127 NH2 ARG D 39 66021 -2795-56411 1008162 D

ATOM 11043 O ARGD 27 53568 15057-47645 1003941 D ATOM 11128 C ARG D 39 59885 -1459 -51809 1005241 D

ATOM 11044 N ALA D 28 51386 1567647589 1007851 D ATOM 11129 O ARG D 39 59844 -2025 -50705 1005564 D

ATOM 11045 CA ALAD 28 51504 16775-46644 1007741 D ATOM 11130 N ASP D 40 59112 -1809 -52834 1005272 D

ATOM 11046 CB ALAD 28 50195 16926-45880 10012801 D ATOM 11131 CA ASP D 40 58151 -2911 -52736 1005067 D

ATOM 11047 C ALAD 28 52658 16688-45656 1007707 D ATOM 11132 CB ASP D 40 58888 4257-52759 1007861 D

ATOM 11048 O ALAD 28 53732 17235-45891 1007809 D ATOM 11133 CG ASP D 40 59795 -4411 -53978 1008075 D

ATOM 11049 N ASND 29 52447 16009-44539 1004267 D ATOM 11134 ODl ASP D 40 59300 -4239-55112 1007763 D

ATOM 11050 CA ASND 29 53495 15940-43531 1004184 D ATOM 11135 OD2 ASP D 40 610004708 -53804 1008087 D

ATOM 11051 CB ASND 29 52912 1634342180 1004260 D ATOM 11136 C ASP D 40 57304 -2797 -51469 1004680 D ATOM 11052 CG ASND 29 52431 17783-42166 1004266 D ATOM 11137 O ASP D 40 56989 -3793 -50828 1004603 D

ATOM 11053 ODlASND 29 53216 18713-42006 1004852 D ATOM 11138 N ASN D 41 56951 -1565-51115 1003684 D

ATOM 11054 ND2ASND 29 51134 17972-42348 1003967 D ATOM 11139 CA ASND 41 56132 -127649940 1003259 D

ATOM 11055 C ASN D 29 54122 14561 -43441 1004018 D ATOM 11140 CB ASN D 41 54836 207549978 1004567 D

ATOM 11056 O ASND 29 54073 1390442387 1003790 D ATOM 11141 CG ASND 41 53717 -1381-49235 1004036 D

ATOM 11057 N ALAD 30 54709 1412144550 1003997 D ATOM 11142 ODl ASN D 41 53415 -0216-49504 1004170 D

ATOM 11058 CA ALAD 30 55338 1280944606 1003479 D ATOM 11143 ND2 ASN D 41 53094 -208748298 1003646 D

ATOM 11059 CB ALAD 30 54702 1196345700 1002780 D ATOM 11144 C ASN D 41 56825 -151748603 1003590 D

ATOM 11060 C ALAD 30 56833 1297344852 1003619 D ATOM 11145 O ASN D 41 56165 -175747585 1003741 D

ATOM 11061 O ALAD 30 57298 1406445160 1004034 D ATOM 11146 N GLN D 42 58153 -1448 -48607 1004092 D

ATOM 11062 N LEU D 31 57581 1188444702 1004244 D ATOM 11147 CA GLN D 42 58907 -165347389 1003884 D ATOM 11063 CA LEUD 31 59019 1193544879 1004191 D ATOM 11148 CB GLN D 42 59606 -300947418 1005242 D

ATOM 11064 CB LEUD 31 59704 1218143543 1003120 D ATOM 11149 CG GLND 42 587084152 -47829 1005451 D

ATOM 11065 CG LEUD 31 59618 1353442882 1003408 D ATOM 11150 CD GLND 42 59440 -547447883 1005397 D

ATOM 11066 CDl LEUD 31 60109 1340541449 1003170 D ATOM 11151 OEl GLN D 42 60514 -558148472 1005340 D

ATOM 11067 CD2LEUD 31 60444 1451343659 1003355 D ATOM 11152 NE2 GLN D 42 58852 -649547278 1005573 D

ATOM 11068 C LEUD 31 59609 1066945447 1004117 D ATOM 11153 C GLN D 42 59940 -056747279 1003773 D

ATOM 110690 LEUD 31 59131 957845175 1004198 D ATOM 11154 O GLN D 42 60422 -006548299 1003807 D

ATOM 11070 N LEU D 32 60684 1084746208 1003952 D ATOM 11155 N LEU D 43 60272 -018946045 1003133 D 65251/C766

ATOM 11156 CA LEU D 43 61298 0827 -45834 1002991 D ATOM 11241 CB TYRD 54 56642 4021 -34387 1003792 D

ATOM 11157 CB LEU D 43 61054 1554 -44509 1001989 D ATOM 11242 CG TYRD 54 56816 5276-35213 1003792 D

ATOM 11158 CG LEU D 43 59753 2373 -44474 1002605 D ATOM 11243 CDl TYR D 54 55734 5859 -35870 1003792 D

ATOM 11159 CDl LEU D 43 59502 2872 -43069 1002614 D ATOM 11244 CEl TYR D 54 55901 6968 -36683 1003792 D

ATOM 11160 CD2 LEU D 43 59826 3516 45464 1002244 D ATOM 11245 CD2 TYR C ) 54 58077 5846 -35394 1003792 D

ATOM 11161 C LEU D 43 62644 0099-45812 1 003193 D ATOM 11246 CE2TYRD 54 58252 6965-36216 1003792 D

ATOM 11162 O LEU D 43 62762 0981 -45249 002855 D ATOM 11247 CZ TYRD 54 57157 7516-36854 1003792 D

ATOM 11163 N VALD 44 63649 0679 -46445 1003361 D ATOM 11248 OH TYRD 54 57314 8614-37664 1003792 D

ATOM 11164 CA VALD 44 64956 0048 -46473 1003329 D ATOM 11249 C TYRD 54 55754 2699 36320 1003571 D

ATOM 11165 CB VALD 44 65376 -0268-47915 1002248 D ATOM 11250 O TYRD 54 56068 2932 -37489 1003456 D

ATOM 11166 CGl VALD 44 66654 -1081-47911 1002367 D ATOM 11251 N SERD 55 54513 2419-35940 1004090 D

ATOM 11167 CG2 VAL D 44 64242 -1016-48628 1001709 D ATOM 11252 CA SERD 55 53417 2349-36889 1004068 D

ATOM 11168 C VALD 44 66006 0936 -45821 003230 D ATOM 11253 CB SERD 55 53535 1077-37714 1004411 D

ATOM 11169 O VALD 44 66268 2050 -46271 1003334 D ATOM 11254 OG SERD 55 52376 0899 -38506 1005067 D

ATOM 11170 N VALD 45 66605 0422 -44758 1004063 D ATOM 11255 C SERD 55 52066 2343 -36204 1004366 D

ATOM 11171 CA VAL D 45 67622 1134 -43996 1004637 D ATOM 11256 O SERD 55 51926 1860-35078 1004080 D

ATOM 11172 CB VAL D 45 67900 0375 -42677 1005088 D ATOM 11257 N GLND 56 51069 2887-36887 1004440 D

ATOM 11173 CGl VALD 45 69128 0918-42000 1005345 D ATOM 11258 CA GLN D 56 49715 2888-36360 1004510 D

ATOM 11174 CG2 VAL D 45 66711 0511-41762 1005428 D ATOM 11259 CB GLN D 56 49346 4205-35700 1004412 D

ATOM 11175 C VALD 45 68918 1308 -44790 004816 D ATOM 11260 CG GLN D 56 47980 4111 -35060 1004572 D

ATOM 11176 O VALD 45 69418 0369 -45396 1004761 D ATOM 11261 CD GLN D 56 47390 5444 -34688 1004884 D

ATOM 11177 N PRO D 46 69480 2522 -44788 004848 D ATOM 11262 OEl GLN C ) 56 46840 6154-35536 1004837 D

ATOM 11178 CD PRO D 46 68818 3766 -44350 1003784 D ATOM 11263 NE2 GLN C 56 47495 5798 -33406 1005195 D

ATOM 11179 CA PRO D 46 70720 2814^15515 1004733 D ATOM 11264 C GLND 56 48709 2649-37462 1004758 D

ATOM 11180 CB PRO D 46 70504 4250 -45972 1003720 D ATOM 11265 O GLND 56 48797 3247-38535 1004566 D

ATOM 11181 CG PRO D 46 69815 4848 -44754 1003790 D ATOM 11266 N VALD 57 47754 1770 -37193 1006429 D

ATOM 11182 C PRO D 46 72029 2665-44731 005077 D ATOM 11267 CA VALD 57 46697 1484-38146 1005866 D

ATOM 11183 O PRO D 46 73102 2820 -45306 005323 D ATOM 11268 CB VALD 57 46744 0032 38647 1004910 D

ATOM 11184 N SER D 47 71958 2382-43435 1 006024 D ATOM 11269 CGlVALD 57 48086 -0239 -39286 1005030 D

ATOM 11185 CA SERD 47 73187 2249 -42662 1005736 D ATOM 11270 CG2 VAL D 57 46492 -0932-37504 1004603 D

ATOM 11186 CB SERD 47 73786 3634 -42424 1005645 D ATOM 11271 C VALD 57 45386 1712 37417 1006127 D

ATOM 11187 OG SERD 47 72890 4447-41688 1005766 D ATOM 11272 O VALD 57 45309 1565-36195 1006238 D

ATOM 11188 C SER D 47 73029 1532 -41319 1 005405 D ATOM 11273 N LEUD 58 44361 2096-38161 1005816 D

ATOM 11189 O SER D 47 71929 1479 -40766 1 0051 19 D ATOM 11274 CA LEU D 58 43060 2322 -37566 1005661 D

ATOM 11190 N GLU D 48 74140 0988 -40806 1004690 D ATOM 11275 CB LEUD 58 42653 3780 -37730 1006265 D

ATOM 11191 CA GLU D 48 74169 0288-39520 1005139 D ATOM 11276 CG LEUD 58 41699 4349-36681 1006467 D

ATOM 11192 CB GLU D 48 75606 -0098-39145 10016558 D ATOM 11277 CDl LEU E 58 40986 5555-37276 1005869 D

ATOM 11193 CG GLU D 48 76364 -0939-40163 10017032 D ATOM 11278 CD2 LEU E 58 40692 3299 -36250 1006245 D

ATOM 11194 CD GLU D 48 76054 -2420 -40057 10017467 D ATOM 11279 C LEUD 58 42060 1433-38285 1005958 D

ATOM 11195 OEl GLU D 48 74919 -2821 -40391 10017641 D ATOM 11280 O LEUD 58 41831 1599-39477 1006121 D

ATOM 11196 OE2 GLU D 48 76949 -3183-39635 10017259 D ATOM 11281 N PHED 59 41481 0478-37569 1006022 D

ATOM 11197 C GLU D 48 73665 1288 -38496 004998 D ATOM 11282 CA PHED 59 40490 -0415-38165 1006112 D

ATOM 11198 O GLU D 48 73857 2492-38661 1005577 D ATOM 11283 CB PHED 59 40594 -1817-37574 1004930 D

ATOM 11199 N GLY D 49 73017 0808 -37444 1003948 D ATOM 11284 CG PHED 59 41878 -2522 -37894 1004579 D

ATOM 11200 CA GLY D 49 72556 1729 -36427 1003714 D ATOM 11285 CDl PHE D 59 42889 -2631 -36944 1004423 D

ATOM 11201 C GLY D 49 71340 1357-35619 003915 D ATOM 11286 CD2 PHE D 59 42066 -3105 -39137 1004775 D

ATOM 11202 O GLY D 49 70656 0368 -35880 1004199 D ATOM 11287 CElPHED 59 44063 -3310-37223 1005015 D

ATOM 11203 N LEU D 50 71089 2182-34614 004778 D ATOM 11288 CE2 PHE D 59 43240 -3787 -39428 1005086 D

ATOM 11204 CA LEU D 50 69954 2032 -33722 1004898 D ATOM 11289 CZ PHE D 59 44240 -3890 -38469 1004946 D

ATOM 11205 CB LEUD 50 70331 2605 -32357 1002734 D ATOM 11290 C PHED 59 39086 0120-37906 1006523 D

ATOM 11206 CG LEUD 50 70410 1685-31 127 1002847 D ATOM 11291 O PHED 59 38819 0714-36860 1006492 D

ATOM 11207 CDl LEU D 50 70788 0280-31525 1002528 D ATOM 11292 N LYSD 60 38195 -0091 -38863 1008395 D

ATOM 11208 CD2 LEU D 50 71400 2267-30131 1002886 D ATOM 11293 CA LYSD 60 36814 0362 38745 1008530 D

ATOM 11209 C LEU D 50 68808 2829 -34346 004536 D ATOM 11294 CB LYS D 60 36627 1720-39419 1006867 D

ATOM 11210 O LEU D 50 68986 3986 -34720 004408 D ATOM 11295 CG LYS D 60 35194 2206-39436 1007486 D

ATOM 11211 N TYRD 51 67638 2218-34478 004237 D ATOM 11296 CD LYS D 60 35084 3523 -40177 1008307 D

ATOM 11212 CA TYRD 51 66512 2915-35089 1004102 D ATOM 11297 CE LYS D 60 33651 4021 -40232 1008582 D

ATOM 11213 CB TYRD 51 66181 2333 -36476 1003787 D ATOM 11298 NZ LYS D 60 33586 5339-40926 1008616 D

ATOM 11214 CG TYRD 51 67141 2654 -37590 1003797 D ATOM 11299 C LYSD 60 35901 -0647-39411 1008481 D

ATOM 11215 CDlTYRD 51 68387 2057 -37657 1003883 D ATOM 11300 O LYSD 60 36198 -1149 -40497 1008756 D

ATOM 11216 CEl TYR D 51 69266 2350 -38693 1003839 D ATOM 11301 N GLYD 61 34788 -0946 -38758 1008626 D

ATOM 11217 CD2TYRD 51 66790 3555 -38587 1003953 D ATOM 11302 CA GLY D 61 33862 -1899 -39322 1008882 D

ATOM 11218 CE2TYRD 51 67660 3859 -39633 1003780 D ATOM 11303 C GLYD 61 32438 -1487 -39054 1009052 D

ATOM 11219 CZ TYRD 51 68892 3259-39681 1003750 D ATOM 11304 O GLYD 61 32140 -0924 -38002 1009369 D

ATOM 11220 OH TYRD 51 69746 3580 -40710 1003773 D ATOM 11305 N GLND 62 31559 -1752 -40018 1009859 D

ATOM 11221 C TYRD 51 65244 2834 -34265 004120 D ATOM 11306 CA GLN D 62 30141 -1433-39883 1009890 D

ATOM 11222 O TYR D 51 64958 1811 -33640 004209 D ATOM 11307 CB GLN D 62 29520 -1171 -41257 10011893 D

ATOM 11223 N LEU D 52 64483 3920 -34268 003565 D ATOM 11308 CG GLND 62 30194 -0061-42051 10012306 D

ATOM 11224 CA LEUD 52 63200 3931 -33589 1003730 D ATOM 11309 CD GLN D 62 30058 1302 -41395 10012900 D

ATOM 11225 CB LEUD 52 62896 5314-33011 1004512 D ATOM 11310 OEl GLN E 62 30500 1507-40266 10012860 D

ATOM 11226 CG LEUD 52 61457 5509-32517 1004101 D ATOM 11311 NE2 GLN E 62 29444 2242 -42104 10012917 D

ATOM 11227 CDl LEU D 52 61065 4407-31562 1004304 D ATOM 11312 C GLND 62 29485 -2648 -39243 1009684 D

ATOM 11228 CD2LEUD 52 61332 6861 -31847 1003534 D ATOM 11313 O GLND 62 29544 -3750-39791 1009835 D

ATOM 11229 C LEUD 52 62221 3587 -34722 003883 D ATOM 11314 N GLYD 63 28876 -2451 -38080 1009314 D

ATOM 11230 O LEU D 52 62207 4260 -35759 003940 D ATOM 11315 CA GLY D 63 28236 -3559 -37396 1009113 D

ATOM 11231 N ILE D 53 61449 ; 514-34540 1003418 D ATOM 11316 C GLYD 63 29202 -4714 -37209 1008921 D

ATOM 11232 CA ILE D 53 60493 2067 -35547 003078 D ATOM 11317 O GLYD 63 30401 -4558 -37432 1008725 D

ATOM 11233 CB ILED 53 60738 0620 -35950 005315 D ATOM 11318 N CYSD 64 28691 -5881-36823 10013658 D

ATOM 11234 CG2 ILE D 53 59765 0213-37027 1005379 D ATOM 11319 CA CYS D 64 29550 -7038-36598 10014082 D

ATOM 11235 CGl ILE D 53 62160 0463 -36461 1005204 D ATOM 11320 C CYSD 64 29400 -8232 -37537 10014691 D

ATOM 11236 CDl ILE D 53 62481 -0957 -36858 1004786 D ATOM 11321 O CYSD 64 28297 -8592 -37946 10014982 D

ATOM 11237 C ILE D 53 59113 : 143 -34952 1003084 D ATOM 11322 CB CYS D 64 29402 -7512-35156 10016536 D

ATOM 11238 O ILE D 53 58927 766 -33804 1 003392 D ATOM 11323 SG CYSD 64 30379 -6503 -34009 10016657 D

ATOM 11239 N TYR D 54 58143 2620 -35724 003999 D ATOM 11324 N PROD 65 30532 -8859 -37894 10010937 D

ATOM 11240 CA TYR D 54 56787 2730 -35205 1003712 D ATOM 11325 CD PROD 65 31889 -8319 37714 10016557 D 65251/C766

ATOM 11326 CA PROD 65 30561 -10022-38783 10011171 D ATOM 11411 CB SERD 76 58255 8352-40524 1005352 D ATOM 11327 CB PROD 65 32040-10142-39151 10016810 D ATOM 11412 OG SERD 76 57030 -8917-40119 1006281 D

ATOM 11328 CG PROD 65 32556 -8746-38988 10016783 D ATOM 11413 C SERD 76 60068 -6773 -40036 1004162 D

ATOM 11329 C PROD 65 30058-11272-38072 10011472 D ATOM 11414 O SERD 76 60129 -5710 -40650 1003777 D

ATOM 11330 O PROD 65 29254-11196-37145 10011499 D ATOM 11415 N ARGD 77 61125 -7522-39777 1004441 D

ATOM 11331 N SERD 66 30553-12422-38514 10013097 D ATOM 11416 CA ARGD 77 62440 -7182 -40273 1004959 D

ATOM 11332 CA SERD 66 30168-13697-37936 10013457 D ATOM 11417 CB ARG D 77 63442 -6965 -39128 1002787 D

ATOM 11333 CB SERD 66 30034-14748-39043 10014006 D ATOM 11418 CG ARGD 77 64891 -7146-39593 1003005 D

ATOM 11334 OG SERD 66 29686-16014-38513 10013722 D ATOM 11419 CD ARGD 77 65892 -6414 -38746 1003092 D

ATOM 11335 C SER D 66 31208-14145-36918 10013512 D ATOM 11420 NE ARG D 77 66704 -7287 -37904 1003336 D ATOM 11336 O SERD 66 32230-13484-36727 10012854 D ATOM 11421 CZ ARGD 77 68039 -7290 -37898 1003679 D

ATOM 11337 N THRD 67 30928-15272-36271 10020084 D ATOM 11422 NHl ARG D 77 68708 -8109 -37088 1003688 D

ATOM 11338 CA THRD 67 31805-15865-35266 10020084 D ATOM 11423 NH2 ARG D 77 68711 -6496-38718 1003665 D

ATOM 11339 CB THRD 67 32710-16954-35890 10017525 D ATOM 11424 C ARG D 77 62911 -8356-41129 1004793 D

ATOM 11340 OGl THRD 67 31901-17901 -36598 10017525 D ATOM 11425 0 ARG D 77 62771 -9518-40747 1005368 D

ATOM 11341 CG2THRD 67 33496-17685-34803 10017525 D ATOM 11426 N ILED 78 63417 -8061 -42312 1005210 D

ATOM 11342 C THRD 67 32696-14863-34538 10020084 D ATOM 11427 CA ILED 78 63969 -9112-43135 1005079 D

ATOM 11343 O THRD 67 32262-14198-33596 10020084 D ATOM 11428 CB ILED 78 63199 -9289 -44506 1007209 D

ATOM 11344 N HIS D 68 33943-14759-34985 10014505 D ATOM 11429 CG2 ILED 78 61876 -8553 -44478 1007259 D

ATOM 11345 CA HISD 68 34898-13858-34359 10014017 D ATOM 11430 CGl ILED 78 64045 -8830 -45682 1007376 D

ATOM 11346 CB HISD 68 35626-14600-33235 10020084 D ATOM 11431 CDl ILED 78 65181 -9770^16014 1007408 D ATOM 11347 CG HISD 68 36226-13701 -32200 10020084 D ATOM 11432 C ILED 78 65402 -8591 -43259 1005296 D

ATOM 11348 CD2 HIS D 68 37507-13540-31794 10020084 D ATOM 11433 O ILED 78 65676 -7633 ^3986 1005151 D

ATOM 11349 NDl HISD 68 35469-12845-31430 10020084 D ATOM 11434 N ALAD 79 66298 -9193-42476 1004906 D

ATOM 11350 CEl HISD 68 36258-12194-30594 10020084 D ATOM 11435 CA ALAD 79 67700 -8785 -42434 1004566 D

ATOM 11351 NE2 HISD 68 37499-12598-30794 10020084 D ATOM 11436 CB ALAD 79 68361 9353-41191 1006301 D

ATOM 11352 C HISD 68 35904-13354-35388 10013600 D ATOM 11437 C ALAD 79 68507 -9165 -43658 1004686 D

ATOM 11353 O HISD 68 36309-14096-36281 10013545 D ATOM 11438 O ALAD 79 68220 10154-44316 1004706 D

ATOM 11354 N VALD 69 36297-12089-35259 1009505 D ATOM 11439 N VALD 80 69525 -8371-43961 1005101 D

ATOM 11355 CA VALD 69 37265-11478-36167 1009478 D ATOM 11440 CA VALD 80 70382 -8647-45107 1005350 D

ATOM 11356 CB VALD 69 36656-10277-36918 10012297 D ATOM 11441 CB VALD 80 71431 -7534^*5312 1005882 D

ATOM 11357 CGl VALD 69 37672 -9710-37891 10012273 D ATOM 11442 CGl VALD 80 72341 -7875-46473 1005722 D

ATOM 11358 CG2VALD 69 35400-10704-37657 10012123 D ATOM 11443 CG2 VAL D 80 70746 -6230 -45573 1006052 D

ATOM 11359 C VALD 69 38486-10990-35395 1009437 D ATOM 11444 C VALD 80 71128 -9953-44867 1005805 D

ATOM 11360 O VALD 69 38357-10343-34356 1009793 D ATOM 11445 O VALD 80 71422 -10681 -45805 I 005664 D

ATOM 11361 N LEUD 70 39670-11310-35906 1009001 D ATOM 11446 N SERD 81 71437-10241 -43607 1004639 D

ATOM 11362 CA LEUD 70 40912-10898-35268 1008523 D ATOM 11447 CA SERD 81 72155-11454-43265 1004925 D

ATOM 11363 CB LEUD 70 41829-12100 35014 1006789 D ATOM 11448 CB SERD 81 73101 -11182 ^2101 1003539 D

ATOM 11364 CG LEUD 70 41392-13119-33956 1006959 D ATOM 11449 OG SERD 81 74099 -10260 -42478 1003843 D

ATOM 11365 CDl LEUD 70 42492-14146-33779 1006463 D ATOM 11450 C SERD 81 71254 -12635 -42922 1005343 D

ATOM 11366 CD2 LEU D 70 41103 12430 32628 1007019 D ATOM 11451 O SERD 81 71744 -13671 -42480 1005395 D

ATOM 11367 C LEUD 70 41651 -9893-36129 1008627 D ATOM 11452 N TYRD 82 69946-12480^13118 1005177 D

ATOM 11368 O LEUD 70 41783-10076-37337 1008638 D ATOM 11453 CA TYRD 82 68992 -13550 -42839 1005381 D

ATOM 11369 N LEUD 71 42127 -8828-35495 1005740 D ATOM 11454 CB TYRD 82 68833-13742-41325 1003173 D

ATOM 11370 CA LEUD 71 42872 -7789-36185 1005734 D ATOM 11455 CG TYRD 82 68058-14992-40937 1003493 D

ATOM 11371 CB LEUD 71 42274 -6418-35859 1005937 D ATOM 11456 CDlTYRD 82 66894-14905-40175 1003722 D

ATOM 11372 CG LEUD 71 40809 -6213-36251 1005704 D ATOM 11457 CElTYRD 82 66159-16035-39861 1003901 D

ATOM 11373 CDl LEUD 71 40340 -4842-35795 1005319 D ATOM 11458 CD2 TYR D 82 68470 16251-41368 1003702 D

ATOM 11374 CD2 LEU D 71 40662 -6346-37756 1005716 D ATOM 11459 CE2 TYR D 82 67743-17389-41061 1003849 D

ATOM 11375 C LEUD 71 44312 -7851-35704 1006137 D ATOM 11460 CZ TYRD 82 66587-17281 -40312 1003918 D

ATOM 11376 O LEUD 71 44566 -7844-34502 1006086 D ATOM 11461 OH TYRD 82 65849-18416-40036 1003760 D

ATOM 11377 N THRD 72 45254 -7936-36635 1005713 D ATOM 11462 C TYRD 82 67644-13211 -43469 1005324 D

ATOM 11378 CA THRD 72 46663 -7979-36254 1005456 D ATOM 11463 O TYRD 82 66698 -12855 -42768 1005342 D

ATOM 11379 CB THRD 72 47317 -9361 -36525 1005902 D ATOM 11464 N GLND 83 67572-13326-44797 1005659 D

ATOM 11380 OGl THRD 72 47605 -9504-37921 1006155 D ATOM 11465 CA GLND 83 66356-13030-45572 1005648 D

ATOM 11381 CG2THRD 72 46394-10477-36088 1005674 D ATOM 11466 CB GLND 83 66575-13336-47053 1005999 D

ATOM 11382 C THRD 72 47462 -6923-37002 1005719 D ATOM 11467 CG GLND 83 66948-12157-47928 1006426 D

ATOM 11383 O THRD 72 47202 -6617-38162 1005823 D ATOM 11468 CD GLND 83 68391 -11756 -47770 1006530 D

ATOM 11384 N HIS D 73 48436 -6359-36311 1005032 D ATOM 11469 OEl GLN D 83 68931 -11006 -48587 1006432 D

ATOM 11385 CA HISD 73 49301 -5345-36874 1005077 D ATOM 11470 NE2 GLN D 83 69033 -12254 -46714 1006280 D

ATOM 11386 CB HISD 73 49013 -3988-36240 1005517 D ATOM 11471 C GLND 83 65067-13740-45158 1005466 D

ATOM 11387 CG HISD 73 49805 -2869-36835 1005804 D ATOM 11472 O GLND 83 64592-14615-45871 1005211 D

ATOM 11388 CD2 HIS D 73 50462 2774-38015 1005980 D ATOM 11473 N THR D 84 64487 -13363 -44029 1005582 D

ATOM 11389 NDl HISD 73 49981 -1658-36200 1006265 D ATOM 11474 CA THRD 84 63245-13980-43605 1004819 D

ATOM 11390 CEl HISD 73 50712 -0865-36963 1006119 D ATOM 11475 CB THRD 84 63459 -15263 -42810 1005711 D

ATOM 11391 NE2 HIS D 73 51016 -1518-38070 1006136 D ATOM 11476 OGl THR D 84 64359-16115-43510 1005766 D ATOM 11392 C HISD 73 50675 -5815-36472 1004985 D ATOM 11477 CG2THRD 84 62128-15979 -42610 1005986 D

ATOM 11393 O HISD 73 50895 -6181 -35318 1004571 D ATOM 11478 C THRD 84 62539 -13030 -42682 1004470 D

ATOM 11394 N THR D 74 51607 -5834-37408 1004542 D ATOM 11479 0 THRD 84 63168-12432-41810 1004601 D

ATOM 11395 CA THRD 74 52942 -6292-37056 1005201 D ATOM 11480 N LYSD 85 61233 -12897 -42860 1005117 D

ATOM 11396 CB THRD 74 52983 -7848-37043 1005150 D ATOM 11481 CA LYSD 85 60458 -12025 -42007 1005103 D

ATOM 11397 OGlTHRD 74 54135 -8312-37750 1005401 D ATOM 11482 CB LYSD 85 58993 -12004 -42440 1006270 D

ATOM 11398 CG2THRD 74 51729 -8428-37681 1005633 D ATOM 11483 CG LYSD 85 58610-10905-43401 1005964 D

ATOM 11399 C THRD 74 54055 -5726-37941 1005086 D ATOM 11484 CD LYSD 85 57099 -10883 -43544 1005804 D

ATOM 11400 O THRD 74 53890 -5597-39149 1004644 D ATOM 11485 CE LYSD 85 56623 -9709 -44379 1005634 D

ATOM 11401 N ILE D 75 55176 -5365 -37321 1004510 D ATOM 11486 NZ LYS D 85 57140 -9758 -45782 1005459 D

ATOM 11402 CA ILED 75 56317 -4826-38048 1004640 D ATOM 11487 C LYSD 85 60525-12549-40582 1005083 D ATOM 11403 CB ILE D 75 56911 3579-37354 1004017 D ATOM 11488 O LYS D 85 60211 -13713 ^10339 1005128 D

ATOM 11404 CG2ILED 75 58164 3124 38072 1003966 D ATOM 11489 N VALD 86 60972 -11703 -39657 1004674 D

ATOM 11405 CGl ILED 75 55876 -2454-37346 1003733 D ATOM 11490 CA VALD 86 61008 -12046 -38237 1004963 D

ATOM 11406 CDl ILED 75 56359 -1 163-36717 1004062 D ATOM 11491 CB VALD 86 62463-12202-37663 1004824 D

ATOM 11407 C ILED 75 57378 -5909-38099 1004954 D ATOM 11492 CGl VALD 86 63174-13342-38355 1005498 D

ATOM 11408 O ILED 75 57839 -6394-37061 1004631 D ATOM 11493 CG2VALD 86 63259 10933-37845 1004951 D

ATOM 11409 N SERD 76 57762 -6285-39314 1004454 D ATOM 11494 C VALD 86 60293-10868-37592 1005030 D

ATOM 11410 CA SERD 76 58758 -7322-39516 1004562 D ATOM 11495 O VALD 86 60613 -9709-37870 1005499 D 65251/C766

ATOM 11496 N ASN D 87 59298-11153-36764 1005657 D ATOM 11581 NE ARGD 98 28601-15857-32460 10019078 D

ATOM 11497 CA ASND 87 58538-10083-36130 1005325 D ATOM 11582 CZ ARGD 98 28213-16923-31765 10019078 D

ATOM 11498 CB ASN D 87 57262-10551-35521 1005164 D ATOM 11583 NHl ARGD 98 27080-17539 32074 10019078

ATOM 11499 CG ASND 87 56314-11188-36565 1005194 D D

ATOM 11500 ODl ASN D 87 56526-11008-37761 1005455 D ATOM 11584 NH2 ARGD 98 28956-17376-30763 10019078

ATOM 11501 ND2ASND 87 55252-11841 -36120 1004890 D D

ATOM 11502 C ASND 87 59295 -9289 -35068 1005207 D ATOM 11585 C ARGD 98 29555-11690-31218 10020084 D

ATOM 11503 O ASND 87 59917 -9869 -34172 1005065 D ATOM 11586 0 ARGD 98 28548-12337-31518 10020084 D

ATOM 11504 N LEUD 88 59237 -7961-35163 1004308 D ATOM 11587 N GLUD 99 29500-10428-30793 10019332 D

ATOM 11505 CA LEU D 88 59895 -7110-34183 1004207 D ATOM 11588 CA GLUD 99 28231 -9716-30631 10019332 D

ATOM 11506 CB LEU D 88 60552 -5919-34855 1003781 D ATOM 11589 CB GLUD 99 28466 -8202-30528 10016861 D

ATOM 11507 CG LEU D 88 61658 -6211 -35857 1003474 D ATOM 11590 CG GLUD 99 29898 -7754-30793 10016861 D

ATOM 11508 CDl LEUD 88 62222 -4891-36335 1003551 D ATOM 11591 CD GLUD 99 30769 -7823-29555 10016861 D

ATOM 11509 CD2 LEU D 88 62743 -7067-35204 1003331 D ATOM 11592 OEl GLU D 99 30684 -8833 -28828 10016861 D

ATOM 11510 C LEUD 88 58868 -6597 33200 1004131 D ATOM 11593 OE2 GLU D 99 31543 -6870-29314 10016861 D

ATOM 11511 O LEUD 88 59103 -6575-32000 1003978 D ATOM 11594 C GLUD 99 27259 -9994-31777 10019332 D

ATOM 11512 N LEUD 89 57723 -6186 -33728 1004695 D ATOM 11595 0 GLUD 99 26103-10343-31543 10019332 D

ATOM 11513 CA LEUD 89 56639 -5650-32921 1004587 D ATOM 11596 N THRDlOO 27741 -9837-33008 10020084 D

ATOM 11514 CB LEUD 89 56619 -4122-33016 1003438 D ATOM 11597 CA THRDlOO 26938 10060 34210 10020084

ATOM 11515 CG LEU D 89 57933 -3408 -32701 1003836 D D

ATOM 11516 CDl LEU D 89 57893 -2031 -33309 1003809 D ATOM 11598 CB THRDlOO 26728-11573-34479 10018351

ATOM 11517 CD2 LEU D 89 58164 -3338-31199 1003748 D D

ATOM 11518 C LEUD 89 55345 -6207 -33484 1004754 D ATOM 11599 OGl THRDlOO 26135-12193-33332 10018379

ATOM 11519 O LEUD 89 55189 -6319-34703 1004826 D D

ATOM 11520 N SER D 90 54412 -6550-32603 1004716 D ATOM 11600 CG2 THR D 100 28057-12252-34786 10018468

ATOM 11521 CA SER D 90 53143 -7105-33038 1004650 D D

ATOM 11522 CB SERD 90 53324 -8563-33421 1005861 D ATOM 11601 C THRDlOO 25573 - ■9372-34141 i 0020084 D

ATOM 11523 OG SER D 90 52080 -9124 -33786 1006283 D ATOM 11602 O THRDlOO 24730 ■ •9716-33311 10020084 D

ATOM 11524 C SER D 90 52073 -7018-31974 1004513 D ATOM 11603 N PRODlOl 25337 - ■8388 -35026 10020084 D

ATOM 11525 O SER D 90 52355 -7142 -30786 1004495 D ATOM 11604 CD PRO D 101 26230 -7965-36120 10013624 D

ATOM 11526 N ALAD 91 50837 -6816-32406 1004623 D ATOM 11605 CA PROD lOl 24077 -7641 -35074 10020084 D

ATOM 11527 CA ALAD 91 49721 -6737-31475 1004432 D ATOM 11606 CB PRODlOI 24140 -6963-36439 10013719 D

ATOM 11528 CB ALA D 91 49475 -5294 -31068 1002627 D ATOM 11607 CG PROD 101 25595 -6667-36577 10013522 D

ATOM 11529 C ALAD 91 48473 -7328 32115 1004829 D ATOM 11608 C PRODlOl 22840 - ■8521 -34912 10020084 D

ATOM 11530 O ALAD 91 48372 -7420 -33336 1005016 D ATOM 11609 O PRODlOl 22516 - •9327 -35786 10020084 D

ATOM 11531 N ILED 92 47528 -7738-31281 1005776 D ATOM 11610 N GLU D 102 22159 -8355-33782 10018251 D

ATOM 11532 CA ILED 92 46287 -8324 -31760 1005774 D ATOM 11611 CA GLU D 102 20954 -9113-33471 I 0018251 D

ATOM 11533 CB ILE D 92 46236 -9823-31444 1005857 D ATOM 11612 CB GLU D 102 20262 -8486-32255 10019127 D

ATOM 11534 CG2 ILE D 92 45000-10437-32061 1006464 D ATOM 11613 CG GLU D 102 18936 -9122-31856 10019247 D

ATOM 11535 CGl ILED 92 47492-10507-31980 1005668 D ATOM 11614 CD GLU D 102 17802 -8768-32802 10019378 D

ATOM 11536 CDl ILE D 92 47615-11961 -31584 1006255 D ATOM 11615 OEl GLU D 102 17505 -7564 32957 10019459

ATOM 11537 C ILED 92 45127 -7640-31054 1005757 D D

ATOM 11538 O ILED 92 45255 -7232-29899 1005865 D ATOM 11616 OE2GLUD102 17206 -9696-33390 10019290

ATOM 11539 N LYS D 93 43999 -7511-31742 1006999 D D

ATOM 11540 CA LYS D 93 42834 -6874 -31150 1007064 D ATOM 11617 C GLU D 102 19992 ■9173-34660 10017907 D

ATOM 11541 CB LYSD 93 42829 -5387 -31498 1009251 D ATOM 11618 O GLU D 102 19375-10208-34917 10017613 D

ATOM 11542 CG LYS D 93 42194 -4508-30430 1009620 D ATOM 11619 N GLY D 103 19872 • ^■ 8063 -35382 10014032 D

ATOM 11543 CD LYS D 93 42724 -3075 -30505 1009597 D ATOM 11620 CA GLYD 103 18981 -8016-36530 10013764 D

ATOM 11544 CE LYSD 93 42197 -2217-29356 1009587 D ATOM 11621 C GLY D 103 18421 - ^■ 6622 -36741 10013551 D

ATOM 11545 NZ LYS D 93 42739 -0823 -29369 1009844 D ATOM 11622 O GLY D 103 17817 -■6327 -37774 10013000 D

ATOM 11546 C LYS D 93 41559 -7550 -31645 1007234 D ATOM 11623 N ALA D 104 18625 ■■5761 -35750 100191 84 D

ATOM 11547 O LYS D 93 41423 -7836 -32833 1007026 D ATOM 11624 CA ALA D 104 18151 -4384-35810 10019184 D

ATOM 11548 N SER D 94 40634 -7819-30723 1008632 D ATOM 11625 CB ALAD 104 16871 -4234 -34983 10010277 D

ATOM 11549 CA SER D 94 39366 -8478 -31047 1008877 D ATOM 11626 C ALA D 104 19232 -3438-35288 10019184 D

ATOM 11550 CB SERD 94 39108 -9631 -30070 1009593 D ATOM 11627 O ALA D 104 ^■ 3501-34115 100191 84 D

ATOM 11551 OG SERD 94 39083 -9177 28726 1009836 D ATOM 11628 N GLU D 105 19735 -■2578-36176 100161 16 D

ATOM 11552 C SER D 94 38216 -7483-30978 1009136 D ATOM 11629 CA GLUD 105 20776 -1586-35876 100161 16 D

ATOM 11553 O SER D 94 37671 -7228-29910 1009263 D ATOM 11630 CB GLUD 105 20792 -1230-34384 10019758 D

ATOM 11554 N PRO D 95 37816 -6926-32129 1008818 D ATOM 11631 CG GLU D 105 19560 -0481 -33906 10019758 D

ATOM 11555 CD PROD 95 38235 -7343-33480 10011926 D ATOM 11632 CD GLU D 105 19374 0844 -34620 10019758 D

ATOM 11556 CA PRO D 95 36727 -5948 -32203 1009212 D ATOM 11633 OEl GLU D 105 19152 0834 -35849 10019758

ATOM 11557 CB PRO D 95 36747 -5530 -33665 I 0012220 D D

ATOM 11558 CG PRO D 95 37114 -6812-34349 10011965 D ATOM 11634 OE2 GLU D 105 19451 1898 33953 10019635

ATOM 11559 C PRO D 95 35381 -6522-31792 1009655 D D

ATOM 11560 O PRO D 95 34887 -6265 -30693 1009998 D ATOM 11635 C GLU D 105 22184 -2001-36310 10016116 D

ATOM 11561 N CYS D 96 34789 -7296-32691 10016677 D ATOM 11636 0 GLU D 105 22428 -2250-37492 10016116 D

ATOM 11562 CA CYS D 96 33505 -7911 -32422 10016656 D ATOM 11637 N ALAD 106 23100 -2054-35342 10017384 D

ATOM 11563 C CYS D 96 33689 -9150 -31568 10016766 D ATOM 11638 CA ALAD 106 24502 -2422-35560 10017384 D

ATOM 11564 O CYS D 96 34189-10175-32033 10016796 D ATOM 11639 CB ALAD 106 24615 -3492-36647 1008640 D

ATOM 11565 CB CYS D 96 32813 -8273-33731 10020084 D ATOM 11640 C ALA D 106 25362 -1211-35922 10017384 D

ATOM 11566 SG CYS D 96 32273 -6814 -34670 10020084 D ATOM 11641 O ALA D 106 25645 -0965-37095 10017384 D

ATOM 11567 N GLN D 97 33289 -9036 -30307 10020084 D ATOM 11642 N LYS D 107 25776 -0462-34904 10017520 D

ATOM 11568 CA GLND 97 33388-10135-29359 100200S4 D ATOM 11643 CA LYS D 107 26604 0729 -35093 10016932 D

ATOM 11569 CB GLND 97 33292 -9590-27931 10017222 D ATOM 11644 CB LYS D 107 26722 1511-33775 10017529 D

ATOM 11570 CG GLN D 97 34266 8457-27637 10017222 D ATOM 11645 CG LYS D 107 25495 2324-33373 10017524 D

ATOM 11571 CD GLN D 97 33882 -7661 -26403 10017222 D ATOM 11646 CD LYS D 107 24291 1450-33073 10017667 D

ATOM 11572 OEl GLN D 97 33779 -8206-25304 10017222 D ATOM 11647 CE LYS D 107 23157 2278-32492 10017271 D

ATOM 11573 NE2GLND 97 33666 -6361 -26582 10017222 D ATOM 11648 NZ LYS D 107 22796 3433-33358 10017297 D

ATOM 11574 C GLN D 97 32245 -11114 -29627 10020084 D ATOM 11649 C LYS D 107 28006 0367 35584 10016480 D

ATOM 11575 O GLN D 97 31590-11584-28697 10020084 D ATOM 11650 0 LYSD 107 28391 -0803-35583 10016393 D

ATOM 11576 N ARG D 98 32012-11402 -30908 10020084 D ATOM 11651 N PROD108 28784 1372-36022 1009929 D

ATOM 11577 CA ARG D 98 30953-12314-31343 10020084 D ATOM 11652 CD PRO D 108 28389 2772-36272 1009821 D

ATOM 11578 CB ARG D 98 31034-13627-30546 10019078 D ATOM 11653 CA PRO D 108 30143 1128-36505 1009803 D

ATOM 11579 CG ARGD 98 29885-14600-30775 10019078 D ATOM 11654 CB PRO D 108 30399 2331-37399 1009736 D

ATOM 11580 CD i ARG D 98 29827-15104-32205 10019078 D ATOM 11655 CG PRO D 108 29702 3424 -36658 1009474 D 65251/C766

ATOM 11656 C PRO D 108 31 125 1062-35333 1009726 D ATOM 11741 C VALD118 64902 -0658-31150 1003878 D ATOM 11657 O PROD 108 30834 1559 -34244 1009544 D ATOM 11742 0 VALD 118 64867 -1630-30425 1004273 D ATOM 11658 N TRPD 109 32281 0442 -35557 1008124 D ATOM 11743 N PHED 119 65550 -0659-32313 1003534 D ATOM 11659 CA TRP D 109 33300 0335-34517 1007869 D ATOM 11744 CA PHED 119 66227 -1852-32815 1003665 D ATOM 11660 CB TRF D 109 33378 -1090 -33965 1009645 D ATOM 11745 CB PHED 119 65311 -2603-33786 1003900 D ATOM 11661 CG TRP D 109 33603 -2142 -35004 1009614 D ATOM 11746 CG PHED119 64041 -3082-33169 1003660 D ATOM 11662 CD2 TRP D 109 34859 -2543-35568 1009515 D ATOM 11747 CDl PHED 119 62953 -2236 33030 1003479 D ATOM 11663 CE2 TRP D 109 34589 -3576 -36493 1009440 D ATOM 11748 CD2 PHED 119 63940 -4381 -32686 1003528 D ATOM 11664 CE3 TRP D 109 36185 -2131 -35382 1009525 D ATOM 11749 CEl PHE D 119 61774 -2684-32410 1003586 D ATOM 11665 CDl TRP D 109 32653 -2922 -35596 1009324 D ATOM 11750 CE2 PHE D 119 62776 ^842-32067 1003609 D ATOM 11666 NEl TRP D 109 33236 -3787-36490 1009156 D ATOM 11751 CZ PHED119 61690 -3996-31927 1003518 D ATOM 11667 CZ2TRPD109 35596 -4203 -37232 1009085 D ATOM 11752 C PHED119 67561 -1594-33522 1003756 D ATOM 11668 CZ3 TRP D 109 37187 -2756-36118 1009501 D ATOM 11753 0 PHED119 67783 -0527-34112 1003366 D ATOM 11669 CH2 TRP D 109 36 S85 -3781 -37031 1009065 D ATOM 11754 N GLND 120 68445 -2589-33454 1004238 D ATOM 11670 C TRP D 109 34674 0747-35019 1008030 D ATOM 11755 CA GLN D 120 69754 -2543 -34102 1004575 D ATOM 11671 O TRP D 109 35026 0525-36176 1008191 D ATOM 11756 CB GLN D 120 70722 -3497 -33407 1006890 D ATOM 11672 N TYRD 110 35443 1356-34127 1007728 D ATOM 11757 CG GLN D 120 71977 -2863 -32846 1006905 D ATOM 11673 CA TYRDIlO 36791 1801 -34439 1007592 D ATOM 11758 CD GLN D 120 72741 -2072-33879 1006865 D ATOM 11674 CB TYRDIlO 36888 3318-34334 1006837 D ATOM 11759 OEl GLND 120 72877 -2502-35021 1006821 D ATOM 11675 CG TYRDIlO 36027 4071-35314 1007192 D ATOM 11760 NE2 GLN D 120 73260 -0912-33482 1007148 D ATOM 11676 CDl TYRD 110 34646 4131 -35161 1007601 D ATOM 11761 C GLN D 120 69501 -3050-35513 1004489 D ATOM 11677 CEl TYRDIlO 33858 4864 -36048 1007633 D ATOM 11762 O GLN D 120 69021 -4172-35674 1004759 D ATOM 11678 CD2TYRD 110 36600 4755-36381 1007215 D ATOM 11763 N LEUD121 69811 -2238-36522 1003265 D ATOM 11679 CE2 TYRD 110 35828 5487 -37271 1007752 D ATOM 11764 CA LEUD 121 69597 -2622-37916 1003431 D ATOM 11680 CZ TYRDIlO 34461 5541-37101 1007781 D ATOM 11765 CB LEUD 121 68544 -1711-38546 1003199 D ATOM 11681 OH TYRDIlO 33705 6286-37979 1007901 D ATOM 11766 CG LEU D 121 67068 -2140-38483 1003026 D ATOM 11682 C TYRDIlO 37772 1158-33461 1007443 D ATOM 11767 CDl LEU D 121 66778 -2964-37261 1003165 D ATOM 11683 O TYRD 110 37514 1087-32257 1007562 D ATOM 11768 CD2 LEU D 121 66186 -0893-38505 1002575 D ATOM 11684 N GLU D ill 38899 0696-33988 1006663 D ATOM 11769 C LEU D 121 70866 -2579-38762 1003635 D ATOM 11685 CA GLU Dill 39917 0056-33165 1006465 D ATOM 117700 LEU D 121 71758 -1776-38492 1004162 D ATOM 11686 CB GLU Dill 39715 -1458-33193 1008618 D ATOM 11771 N GLUD122 70934 -3446-39779 1004811 D ATOM 11687 CG GLUDlIl 39913 -2114-31850 1009310 D ATOM 11772 CA GLUD122 72071 -3533-40705 1004965 D ATOM 11688 CD GLU Dill 38935 -1601-30811 1009807 D ATOM 11773 CB GLU D 122 72319 -4971 -41174 10010493 D ATOM 11689 OEl GLUD 111 37715 -1734 31037 1009828 D ATOM 11774 CG GLU D 122 72642 -6018-40135 10010797 D ATOM 11690 OE2GLUD1I1 39380 -1066 -29772 10010523 D ATOM 11775 CD GLUD122 72742 -7416-40765 10011325 D ATOM 11691 C GLU Dill 41320 0402 -33673 1006523 D ATOM 11776 OEl GLU D 122 71730 -7906-41318 10011475 ATOM 11692 O GLU D ill 41724 -0049 -34739 1007059 D D ATOM 11693 N PROD 112 42073 1227 32922 1005880 D ATOM 11777 OE2GLUD122 73835 -8023-40717 10011334 ATOM 11694 CD PRO D 112 41594 2103-31836 1005596 D D ATOM 11695 CA PRO D 112 43426 1616-33322 1005803 D ATOM 11778 C GLU D 122 71755 -2739-41967 1004845 D ATOM 11696 CB PRO D 112 43511 3046 -32829 1005203 D ATOM 11779 0 GLUD 122 70601 -2615-42363 1004964 D ATOM 11697 CG PRO D 112 42822 2942-31516 1005316 D ATOM 11780 N LYSD123 72783 -2220-42619 1005435 D ATOM 11698 C PRO D 112 44474 0735 -32667 1005506 D ATOM 11781 CA LYS D 123 72560 -1505-43865 1005520 D ATOM 11699 O PROD 112 44219 0136-31629 1005519 D ATOM 11782 CB LYSD 123 73883 -1010-44446 1006254 D ATOM 11700 N ILE D 113 45648 0648 -33280 1005492 D ATOM 11783 CG LYSD 123 73751 -0457-45840 1005870 D ATOM 11701 CA ILED 113 46748 -0142-32731 1005689 D ATOM 11784 CD LYSD 123 75093 -0049-46395 1005637 D ATOM 11702 CB ILE D 113 46866 -1523 -33379 1004472 D ATOM 11785 CE LYSD 123 74950 0434-47827 1005810 D ATOM 11703 CG2 ILE D 113 48050 -2250-32775 1004074 D ATOM 11786 NZ LYSD 123 76273 0713^8462 1006211 D ATOM 11704 CGl ILED 113 45598 -2342 -33159 1004178 D ATOM 11787 C LYSD123 71925 -2511 -44825 1005602 D ATOM 11705 CDl ILED 113 45709 -3780 -33704 1004226 D ATOM 11788 0 LYS D 123 72448 -3606-45025 1006078 D ATOM 11706 C ILED 113 48067 0582 -32985 1006111 D ATOM 11789 N GLYD124 70783 2149-45393 1003930 D ATOM 11707 O ILED 113 48360 0966-34115 1006451 D ATOM 11790 CA GLYD 124 70120 -3041 -46323 1004041 D ATOM 11708 N TYRD 114 48858 0770-31935 1005361 D ATOM 11791 C GLY D 124 68888 -3745-45785 1004182 D ATOM 11709 CA TYR D 114 50143 1449-32064 1005189 D ATOM 11792 0 GLYD124 68132 -4335-46555 1004262 D ATOM 11710 CB TYRDlM 50230 2636-31113 1004106 D ATOM 11793 N ASPD125 68673 -3700-44473 1004724 D ATOM 11711 CG TYR D 114 51448 3498-31341 1003892 D ATOM 11794 CA ASPD 125 67505 -4358-43895 1004603 D ATOM 11712 CDl TYRD 114 51433 4513-32298 1004321 D ATOM 11795 CB ASP D 125 67512 -4227-42373 1006814 D ATOM 11713 CEl TYR D 114 52559 5306-32531 1004278 D ATOM 11796 CG ASP D 125 68592 -5064 -41714 1007360 D ATOM 11714 CD2TYRD114 52632 3291-30611 1003909 D ATOM 11797 ODl ASP D 125 69223 -5895-42403 1007525 D ATOM 11715 CE2TYRD114 53766 4074 30832 1004342 D ATOM 11798 OD2 ASP D 125 68796 -4893-40495 1007226 D ATOM 11716 CZ TYR D 114 53723 5080 -31796 1004350 D ATOM 11799 C ASPD125 66194 -3787-44442 1004508 D ATOM 11717 OH TYR D 114 54847 5849 -32039 1004300 D ATOM 11800 0 ASPD125 66105 -2599-44771 1004199 D ATOM 11718 C TYRDlU 51263 0470-31751 1005173 D ATOM 11801 N ARG D 126 65183 -4645-44533 1005690 D ATOM 11719 O TYRD 114 51135 -0388-30881 1005464 D ATOM 11802 CA ARG D 126 63870 -4258^15035 1005238 D ATOM 11720 N LEU D 115 52365 0612 -32466 1004920 D ATOM 11803 CB ARGD 126 63441 -5190-46171 1007496 D ATOM 11721 CA LEU D 115 53513 -0263-32298 1004824 D ATOM 11804 CG ARG D 126 64223 -5065-47451 1007345 D ATOM 11722 CB LEU D 115 53537 -1281 -33436 1004922 D ATOM 11805 CD ARG D 126 63856 -6199-48415 1007837 D ATOM 11723 CG LEUD 115 53227 -2757 -33194 1005247 D ATOM 11806 NE ARGD 126 64301 -5921^19782 1008192 D ATOM 11724 CDl LEUD 115 52120 -2922 -32166 1005085 D ATOM 11807 CZ ARG D 126 63681 -5095 -50634 1008515 D ATOM 11725 CD2 LEUD 115 52850 -3395 -34537 1005577 D ATOM 11808 NHl ARG D 126 64168 -4897-51858 1008482 ATOM 11726 C LEU D 115 54775 0584 -32349 1005068 D D ATOM 11727 O LEU D 115 54873 1508-33156 1005321 D ATOM 11809 NH2 ARG D 126 62559 -4479 -50276 1008334 ATOM 11728 N GLYD 116 55740 0280-31492 1004097 D D ATOM 11729 CA GLY D 116 56965 1048-31516 1003531 D ATOM 11810 C ARGD126 62834 -4345-43916 1005322 D ATOM 11730 C GLYD 116 58060 0548-30599 1003916 D ATOM 11811 O ARG D 126 62668 -5390-43295 1005044 D ATOM 11731 O GLY D 116 57784 0127-29484 1003804 D ATOM 11812 N LEUD127 62124 -3254-43666 1004934 D ATOM 11732 N GLYD 117 59304 0606-31067 1003294 D ATOM 11813 CA LEUD 127 61102 -3243 ^12627 1004572 D ATOM 11733 CA GLYD 117 60429 0159-30269 1003594 D ATOM 11814 CB LEUD 127 61290 -2021 -41737 1003955 D ATOM 11734 C GLY D 117 61748 0507 30933 1003725 D ATOM 11815 CG LEUD 127 62651 -1992-41043 1003853 D ATOM 11735 O GLYD 117 61764 0935 -32094 1003863 D ATOM 11816 CDl LEU D 127 62862 -0617-40435 1003911 D ATOM 11736 N VALD 118 62853 0335 -30206 1003809 D ATOM 11817 CD2 LEU D 127 62724 -3094 -39969 1003919 D ATOM 11737 CA VAL D 118 64179 0631-30747 1004087 D ATOM 11818 C LEU D 127 59709 -3235-43246 1004547 D ATOM 11738 CB VALD 118 65004 1414-29725 1004123 D ATOM 11819 0 LEUD127 59456 -2507-44209 1004167 D ATOM 11739 CGl VAL D 118 66409 1660-30251 1004263 D ATOM 11820 N SERD 128 58810 -4050-42696 1004943 D ATOM 11740 CG2 VALD118 64321 2736-29448 1004129 D ATOM 11821 CA SER D 128 57443 -4143-43200 1004910 D 65251/C766

ATOM 11822 CB SERD 128 57160 -5544 -43722 1005689 D ATOM 11907 CD2 LEU D 138 37967 5440 -39725 1006292 D ATOM 11823 OG SER D 128 58273 -6055 -44420 1006274 D ATOM 11908 C LEU D 138 41206 4346-42333 1 006129 D ATOM 11824 C SER D 128 56453 -3852 -42092 1004828 D ATOM 11909 O LEU D 138 41826 4827-41387 1 006044 D ATOM 11825 O SER D 128 56656 -4257 -40953 1004956 D ATOM 11910 N PHE D 139 41411 4714-43588 1 006796 D ATOM 11826 N ALAD 129 55384 -3142 -42434 1004032 D ATOM 11911 CA PHED 139 42383 5738-43916 1006934 D ATOM 11827 CA ALA D 129 54320 -2820-41482 1004129 D ATOM 11912 CB PHED 139 43457 5170-44851 1007423 D ATOM 11828 CB ALA D 129 54225 -1299 -41267 1002563 D ATOM 11913 CG PHED 139 42916 4327 -45974 1007338 D ATOM 11829 C ALA D 129 53057 -3357 -42144 1004006 D ATOM 11914 CDl PHE D 139 43687 3300-46513 1007291 D ATOM 11830 O ALA D 129 52479 -2699 -43010 1004094 D ATOM 11915 CD2PHED139 41655 4565-46512 1007599 D ATOM 11831 N GLU D 130 52639 -4555 -41748 1004908 D ATOM 11916 CEl PHE D 139 43212 2526 -47565 1007755 D ATOM 11832 CA GLU D 130 51477 -5191 -42357 1005005 D ATOM 11917 CE2PHED139 41175 3795 -47563 1007353 D ATOM 11833 CB GLU D 130 51921 -6499 ^3004 1009781 D ATOM 11918 CZ PHED 139 41957 2775-48089 1007747 D ATOM 11834 CG GLU D 130 52987 -6296 -44059 1009735 D ATOM 11919 C PHE D 139 41653 6904 -44559 1007337 D ATOM 11835 CD GLU D 130 53787 -7552-44354 10010284 D ATOM 11920 O PHE D 139 42138 7511 -45510 1 007347 D ATOM 11836 OEl GLU D 130 54646 -7504 -45266 10010421 D ATOM 11921 N ALA D 140 40477 7209-44014 I 007845 D ATOM 11837 OE2 GLU D 130 53567 -8581 43676 10010265 D ATOM 11922 CA ALA D 140 39638 8292-44518 1007975 D ATOM 11838 C GLU D 130 50318 -5455-41416 1004644 D ATOM 11923 CB ALA D 140 38194 8072-44100 1006614 D ATOM 11839 O GLUD 130 50482 -5433-40198 1004636 D ATOM 11924 C ALA D 140 40088 9661-44051 1 008014 D ATOM 11840 N ILED 131 49142 -5688-41995 1006182 D ATOM 11925 O ALA D 140 40151 10597 -44843 1008203 D ATOM 11841 CA ILE D 131 47924 -5999 -41237 1006436 D ATOM 11926 N GLU D 141 40397 9780 -42764 1 0010992 D ATOM 11842 CB ILE D 131 46902 -4846 -41256 1005040 D ATOM 11927 CA GLU D 141 40813 11059-42211 10011310 ATOM 11843 CG21LED 131 47455 -3650 -40504 1005063 D D ATOM 11844 CGl ILED 131 46551 -4497-42706 1004659 D ATOM 11928 CB GLUD 141 40768 11025 40678 10020084 ATOM 11845 CDl ILED 131 45529 -3382 -42840 1004520 D D ATOM 11846 C ILED 131 47285 7196-41914 1006625 D ATOM 11929 CG GLU D 141 41047 12374-40014 10020084 ATOM 11847 O ILED 131 47598 -7502 -43058 I 006697 D D ATOM 11848 N ASN D 132 46376 -7863-41219 1006398 D ATOM 11930 CD GLU D 141 42531 12660-39832 10020084 ATOM 11849 CA ASN D 132 45723 -9041 -41773 1006098 D D ATOM 11850 CB ASN D 132 45540 -10077 -40670 1005642 D ATOM 11931 OEl GLU D 141 42906 13849-39765 10020084 ATOM 11851 CG ASN D 132 44568 -9618-39610 1005512 D D ATOM 11852 ODl ASN D 132 44566 -8458-39203 1005681 D ATOM 11932 OE2 GLU D 141 43323 11700 -39740 10020084 ATOM 11853 ND2 ASN D 132 43735-10531 -39148 1005295 D D ATOM 11854 C ASN D 132 44376 -8760 -42445 1005863 D ATOM 11933 C GLUD141 42182 11525-42677 10011520 D ATOM 11855 O ASN D 132 43976 -9482-43353 1006180 D ATOM 11934 O GLUD141 42276 12327-43603 10011888 D ATOM 11856 N ARGD 133 43677 -7716 -42007 1006778 D ATOM 11935 N SERD142 43246 11028-42058 1008232 D ATOM 11857 CA ARG D 133 42371 -7382 -42575 1006337 D ATOM 11936 CA SERD 142 44572 11488-42445 1008531 D ATOM 11858 CB ARG D 133 41289 -7476-41497 1009315 D ATOM 11937 CB SER D 142 44625 13005 42306 1005812 D ATOM 11859 CG ARG D 133 41122 -8861 -40906 1009573 D ATOM 11938 OG SERD 142 45739 13534-42985 1005900 D ATOM 11860 CD ARG D 133 40810 -9890 -41987 10010097 D ATOM 11939 C SER D 142 45725 10873-41644 1008663 D ATOM 11861 NE ARG D 133 39584 -9576-42719 1009883 D ATOM 119400 SER D 142 46428 9966-42122 1009172 D ATOM 11862 CZ ARG D 133 38356 -9677-42213 1009993 D ATOM 11941 N GLY D 143 45938 11384 ^40436 1004882 D ATOM 11863 NHl ARG D 133 37303 -9366-42956 10010261 D ATOM 11942 CA GLY D 143 47008 10846-39621 1004629 D ATOM 11864 NH2 ARG D 133 38179-10098-40968 1009922 D ATOM 11943 C GLYD143 46556 9632-38837 1004436 D ATOM 11865 C ARG D 133 42319 -5996-43212 1006796 D ATOM 11944 0 GLYD143 46973 9470-37691 1004635 D ATOM 11866 O ARG D 133 41629 -5100-42717 1007032 D ATOM 11945 N GLN D 144 45723 8782-39451 1005106 D ATOM 11867 N PRO D 134 43031 -5809-44339 1005973 D ATOM 11946 CA GLND 144 45185 7575-38811 1004559 D ATOM 11868 CD PROD 134 43766 -6829 -45111 1005011 D ATOM 11947 CB GLND 144 43739 7342-39249 1007425 D ATOM 11869 CA PRO D 134 43059 -4520 -45037 1006345 D ATOM 11948 CG GLN D 144 42872 8582-39199 1007353 D ATOM 11870 CB PROD 134 43985 -4786-46216 1005283 D ATOM 11949 CD GLN D 144 41418 8286-39499 1007350 D ATOM 11871 CG PROD 134 43763 -6231 -46495 1005483 D ATOM 11950 OEl GLN D 144 41096 7612-40481 1007907 D ATOM 11872 C PRO D 134 41693 -4036 -45470 1006863 D ATOM 11951 NE2 GLN D 144 40525 8801 -38658 1007204 D ATOM 11873 O PRO D 134 41536 -2884 -45868 1007167 D ATOM 11952 C GLND144 45988 6310-39103 1004739 D ATOM 11874 N ASP D 135 40703 -4916 -45394 1007122 D ATOM 11953 O GLN D 144 45927 5345 -38345 1004970 D ATOM 11875 CA ASP D 135 39346 -4544 -45774 1006768 D ATOM 11954 N VALD 145 46735 6313-40204 1004702 D ATOM 11876 CB ASP D 135 38528 -5798-46085 10010815 D ATOM 11955 CA VALD 145 47543 5159-40592 1004527 D ATOM 11877 CG ASPD 135 38760 -6905 -45087 10010762 D ATOM 11956 CB VAL D 145 46855 4381 ^1728 1003265 D ATOM 11878 ODl ASP D 135 38245 6800-43957 10010356 D ATOM 11957 CGl VAL D 145 47651 3129-42092 1003081 D ATOM 11879 OD2ASPD135 39466 -7878^15425 10010920 D ATOM 11958 CG2 VAL D 145 45468 4002-41298 1002973 D ATOM 11880 C ASP D 135 38666 -3700 -44691 1006639 D ATOM 11959 C VALD145 48921 5623-41058 1004638 D ATOM 11881 O ASP D 135 37613 -3108 ^4929 1007308 D ATOM 11960 0 VAL D 145 49044 6293-42081 1004906 D ATOM 11882 N TYRD 136 39283 -3640 -43510 1006798 D ATOM 11961 N TYR D 146 49953 5269-40301 1004848 D ATOM 11883 CA TYRD 136 38756 -2857-42393 1006919 D ATOM 11962 CA TYRD 146 51311 5669-40641 1004669 D ATOM 11884 CB TYRD 136 38765 -3680-41108 1007623 D ATOM 11963 CB TYR D 146 51663 7032 ^tO 013 1004435 D ATOM 11885 CG TYRD 136 37689 -4734-41015 1007584 D ATOM 11964 CG TYRD 146 51328 7156 38541 1004438 D ATOM 11886 CDl TYR D 136 38022 -6076 -40851 1007544 D ATOM 11965 CDl TYR D 146 50046 7516-38118 1004377 D ATOM 11887 CEl TYR D 136 37042 -7046 -40706 1007799 D ATOM 11966 CEI TYRD 146 49722 7589-36765 1004256 D ATOM 11888 CD2TYRD136 36339 -4388-41038 1007801 D ATOM 11967 CD2 TYR D 146 52281 6875-37568 1003997 D ATOM 11889 CE2TYRD136 35348 -5354 -40895 1007748 D ATOM 11968 CE2 TYR D 146 51971 6943-36202 1004202 D ATOM 11890 CZ TYRD 136 35709 -6681 -40728 1007878 D ATOM 11969 CZ TYR D 146 50693 7300 -35807 1004206 D ATOM 11891 OH TYRD 136 34741 -7647-40571 1008262 D ATOM 11970 OH TYRD 146 50402 7358-34459 1004304 D ATOM 11892 C TYR D 136 39596 -1603-42163 1007110 D ATOM 11971 C TYRD 146 52337 4632 -40214 1004500 D ATOM 11893 O TYRD 136 39384 -0869-41199 1007398 D ATOM 11972 0 TYR D 146 52063 3725-39425 1004317 D ATOM 11894 N LEU D 137 40551 -1365 43050 1006514 D ATOM 11973 N PHED 147 53539 4801 -40733 1003689 D ATOM 11895 CA LEUD 137 41433 -0214-42930 1006185 D ATOM 11974 CA PHE D 147 54641 3890-40489 1003641 D ATOM 11896 CB LEU D 137 42542 -0301 -43977 1005137 D ATOM 11975 CB PHE D 147 54538 2761-41522 1003359 D ATOM 11897 CG LEU D 137 43979 0362 -43470 1004910 D ATOM 11976 CG PHE D 147 55730 1853-41583 1003264 D ATOM 11898 CDl LEU D 137 44915 -0184-44649 1005124 D ATOM 11977 CDl PHED 147 56427 1496-40427 1003313 D ATOM 11899 CD2LEUD137 44221 0727-42436 1005286 D ATOM 11978 CD2 PHE D 147 56108 1280-42808 1003497 D ATOM 11900 C LEU D 137 40735 1127-43086 1006122 D ATOM 11979 CEl PHED 147 57479 0573^10491 1003346 D ATOM 11901 O LEU D 137 40195 1415-44151 1006007 D ATOM 11980 CE2 PHE D 147 57150 0360-42878 1003354 D ATOM 11902 N LEU D 138 40747 1948 -42034 1006014 D ATOM 11981 CZ PHE D 147 57839 0002-41717 1003438 D ATOM 11903 CA LEU D 138 40144 3279-42119 1005794 D ATOM 11982 C PHED 147 55908 4719-40674 1003795 D ATOM 11904 CB LEUD 138 39338 3649 -40863 1006388 D ATOM 11983 O PHED147 56067 5418 41676 1003543 D ATOM 11905 CG LEU D 138 38948 5146-40843 1006000 D ATOM 11984 N GLYD 148 56802 4665-39702 1002626 D ATOM 11906 CDl LEU D 138 38350 5543-42183 1006157 D ATOM 11985 CA GLY D 148 58017 5447-39821 1003074 D 65251/C766

ATOM 11986 C GLY D 148 59186 4944-39006 1003296 D ATOM 12071 CB TYRD 159 46567 35691 -60532 1003087 D ATOM 11987 O GLYD 148 59039 4065-38150 1003557 D ATOM 12072 CG TYR D 159 46014 34979-59327 1003443 D

ATOM 11988 N ILED149 60357 5496-39294 1003811 D ATOM 12073 CDl TYR D 159 46656 33854 -58797 1003443

ATOM 11989 CA ILE D 149 61579 5135-38592 1003652 D D

ATOM 11990 CB ILE D 149 62301 3925-39238 1004108 D ATOM 12074 CEl TYR D 159 46186 33226-57548 1003443 D

ATOM 11991 CG2 ILED 149 61338 2788 39475 1004163 D ATOM 12075 CD2TYRD159 44875 35458 -58677 1003443

ATOM 11992 CGI ILED 149 62889 4315-40578 1003712 D D

ATOM 11993 CD1 ILED149 63715 3212-41149 1004037 D ATOM 12076 CE2TYRD159 44390 34836-57513 1003443 D

ATOM 11994 C ILED149 62527 6322-38612 1003856 D ATOM 12077 CZ TYRD 159 45057 33721 -57001 1003443 D

ATOM 11995 0 ILED149 62553 7111 -39555 1004373 D ATOM 12078 OH TYR D 159 44619 33135-55830 1003443 D ATOM 11996 N ILED 150 63315 6435-37559 1 O038S3 D ATOM 12079 C TYR D 159 46855 35963 -62975 1 003840 D

ATOM 11997 CA ILE D 150 64275 7521-37421 1003934 D ATOM 12080 O TYRD 159 48071 35967-63126 1 003840 D

ATOM 11998 CB ILE D 150 63707 8635-36484 1004158 D ATOM 12081 N THR D 160 4605036708 63720 1 004826 D

ATOM 11999 CG2 ILED 150 63294 8049-35141 1004488 D ATOM 12082 CA THRD 160 46617 37560-64751 1004826 D

ATOM 12000 CGl ILED 150 64745 9723-36258 1003957 D ATOM 12083 CB THRD 160 46580 36843-66110 1005902 D

ATOM 12001 CDl ILED 150 64987 10579-37457 1003758 D ATOM 12084 OGl THR D 160 47219 35568 65986 1004636

ATOM 12002 C ILE D 150 65543 6915-36826 1004068 D D

ATOM 12003 O ILED 150 65490 6109-35901 1003979 D ATOM 12085 CG2THRD160 47293 37651 -67162 1004636

ATOM 12004 N ALA D 151 66687 7288-37373 1005291

ATOM 12005 CA ALA D 151 67959 6777-36876 1005165 D ATOM 12086 C THR D 160 45963 38932-64915 1 004826 D

ATOM 12006 CB ALA D 151 69031 6933-37943 1002130 D ATOM 12087 O THR D 160 4474039036 -65050 1 004826 D ATOM 12007 C ALAD151 68372 7531-35619 1005261 D ATOM 12088 N VAL D 161 46776 39987-64868 1 I 003808 D

ATOM 12008 O ALA D 151 68497 8751 -35635 1005499 D ATOM 12089 CA VAL D 161 46253 41336-65113 1003808 D

ATOM 12009 N LEU D 152 68589 6804-34533 1007388 D ATOM 12090 CB VALD 161 46573 42336 -63991 1005365 D

ATOM 12010 CA LEU D 152 68993 7429 33287 1007786 D ATOM 12091 CGl VALD 161 4617441764-62670 1003816

ATOM 12011 CB LEUD152 68191 6853-32129 1006580 D D

ATOM 12012 CG LEU D 152 66687 7075-32250 1006705 D ATOM 12092 CG2VALD161 48028 42682 -64001 1003816

ATOM 12013 CDl LEU D 152 65972 6430-31078 1006474 D D

ATOM 12014 CD2 LEU D 152 66398 8557-32298 1006625 D ATOM 12093 C VAL D 161 46905 41801-66418 1 003808 D

ATOM 12015 C LEU D 152 70478 7218-33041 1008071 D ATOM 12094 O VALD 161 4809941596 66634 1 1003808 D

ATOM 120160 LEUD152 71267 8161 -33116 1008657 D ATOM 12095 N THR D 162 4610942396-67295 I 005909 D

ATOM 12017 N ILED153 48240 13732-61027 1004286 D ATOM 12096 CA THRD 162 4660442851 -68589 1005909 D ATOM 12018 CA ILE D 153 47268 14807-60907 1004286 D ATOM 12097 CB THRD 162 4595242059 -69729 1008307 D

ATOM 12019 CB ILE D 153 46347 14600-59700 1003419 D ATOM 12098 OGl THR D 162 45711 40720-69297 1005440

ATOM 12020 CG2ILED153 45433 13426-59952 1003097 p U.

ATOM 12021 CGl ILED 153 47177 14380-58437 1003097 D ATOM 12099 CG2THRD162 46861 42024-70935 1005440

ATOM 12022 CDl ILED 153 46333 14185-57190 1003097 D D

ATOM 12023 C ILED 153 47942 16162-60783 1004286 D ATOM 12100 C THR D 162 46291 44324-68811 1 005909 D

ATOM 12024 O ILED 153 49101 16268-60380 1004286 D ATOM 12101 O THRD 162 45293 44834 -68305 1 005909 D

ATOM 12025 N THR D 154 47179 17199-61108 1004330 D ATOM 12102 N LEU D 163 4714645008-69567 1 009047 D

ATOM 12026 CA THRD 154 47672 18569-61107 1004330 D ATOM 12103 CA LEUD 163 46918 46413-69857 1009047 D

ATOM 12027 CB THRD 154 48093 18935-62536 1004708 D ATOM 12104 CB LEU D 163 4821047100-70281 10012309 D

ATOM 12028 OGl THR D 154 49517 18888-62622 1005736 D ATOM 12105 CG LEU D 163 4854448333 -69437 1007118 D

ATOM 12029 CG2THRD154 47567 20311 62949 1005736 D ATOM 12106 CDl LEUD 163 49722 49067-70060 1007118 D

ATOM 12030 C THRD154 46680 19610-60621 1004330 D ATOM 12107 CD2LEUD 163 47346 49253-69346 1007118 D

ATOM 12031 O THR D 154 45488 19496-60868 1004330 D ATOM 12108 C LEU D 163 4589346527 -70975 1 009047 D

ATOM 12032 N LEU D 155 47181 20625-59927 1003269 D ATOM 12109 O LEUD 163 4542747619-71294 1 009047 D

ATOM 12033 CA LEU D 155 46345 21727-59461 1003269 D ATOM 12110 N LYS D 164 45533 45391 -71562 1 0018419 D

ATOM 12034 CB LEU D 155 46115 21656 -57942 1003597 D ATOM 12111 CA LYS D 164 4455845385 -72644 10018419 D

ATOM 12035 CG LEU D 155 45165 22748-57412 1003255 D ATOM 12112 CB LYS D 164 43153 45649-72092 1006051 D

ATOM 12036 CDl LEU D 155 4385622717 -58172 1003255 D ATOM 12113 CG LYS D 164 42281 44391 -71979 1006026 D

ATOM 12037 CD2LEUD155 44915 22551 -55939 1003255 D ATOM 12114 CD LYS D 164 4205743762 -73347 1006026 D

ATOM 12038 C LEU D 155 4708923011 -59834 1003269 D ATOM 12115 CE LYS D 164 41192 42513-73283 1006026 D

ATOM 12039 O LEU D 155 4820223248-59365 1003269 D ATOM 12116 NZ LYS D 164 4086741987-74661 1006026 D

ATOM 12040 N LYS D 156 4649023827 -60694 1004647 D ATOM 12117 C LYS D 164 4493646472 -73637 1 0018419 D

ATOM 12041 CA LYS D 156 4713725061-61128 1004647 D ATOM 12118 O LYSD 164 4608046927 -73653 10018419 D

ATOM 12042 CB LYS D 156 47555 24944-62595 1005695 D ATOM 12119 N ASP D 165 4398646883 -74472 1 0020084 D

ATOM 12043 CG LYS D 156 48331 26159-63083 1005914 D ATOM 12120 CA ASP D 165 44258 47940-75435 10020084 D

ATOM 12044 CD LYS D 156 4875726061 -64544 1005914 D ATOM 12121 CB ASP D 165 43041 48175-76345 10013878 D

ATOM 12045 CE LYS D 156 4758426184 -65509 1005914 D ATOM 12122 CG ASP D 165 41740 48305 -75569 10013878 D

ATOM 12046 NZ LYS D 156 4803226202 -66939 1005914 D ATOM 12123 ODl ASP D 165 41601 49283 -74798 10013878

ATOM 12047 C LYSD 156 46289 26321-60960 1004647 U D

ATOM 12048 O LYS D 156 45131 26352-61354 1004647 D ATOM 12124 OD2ASPD165 4086047424 -75732 10013878

ATOM 12049 N TYRD157 4688227357-60376 1004511

ATOM 12050 CA TYRD 157 46222 28646-60165 1004511 D ATOM 12125 C ASP D 165 44583 49190-74628 1 0020084 D

ATOM 12051 CB TYRD 157 4632029069-58695 1004396 D ATOM 12126 O ASPD 165 4536249135 -73676 10020084 D ATOM 12052 CG TYRD 157 45398 28327-57754 1002630 D ATOM 12127 N ASP D 166 43988 50318-74983 10010207 D

ATOM 12053 CDl TYR D 157 44605 27267-58201 1002630 D ATOM 12128 CA ASP D 166 44271 51527-74234 10010207 D

ATOM 12054 CEl TYR D 157 43739 26590 -57335 1002630 D ATOM 12129 CB ASP D 166 44336 52722-75184 10020084 D

ATOM 12055 CD2TYRD157 45305 28692-56413 1002630 D ATOM 12130 CG ASP D 166 45497 52622-76157 10020084 D

ATOM 12056 CE2TYRD 157 44436 28022-55535 1002630 D ATOM 12131 ODl ASPD 166 45532 51651-76943 10020084

ATOM 12057 CZ TYRD 157 4366026974-56010 1002630

ATOM 12058 OH TYRD 157 42817 26311-55153 1002630 D ATOM 12132 OD2ASPD166 46377 53508-76130 10020084

ATOM 12059 C TYRD157 46935 29679-61051 1004511 D D

ATOM 12060 0 TYR D 157 4817329804-61019 1004511 D ATOM 12133 C ASP D 166 4328051788 -73097 10010207 D

ATOM 12061 N ASN D 158 4615630417-61840 1003849 D ATOM 12134 O ASP D 166 42066 51910-73317 1 0010207 D

ATOM 12062 CA ASN D 158 4670631417-62751 1003849 D ATOM 12135 N GLY D 167 43812 51842-71874 1 007133 D ATOM 12063 CB ASN D 158 46529 30934-64208 1003054 D ATOM 12136 CA GLY D 167 42978 52120 -70726 1007133 D

ATOM 12064 CG ASN D 158 47118 31899 -65248 1004124 D ATOM 12137 C GLYD 167 43217 51377-69423 1 007133 D

ATOM 12065 ODl ASN D 158 47613 32971 -64916 1004124 D ATOM 12138 O GLYD 167 44273 51443-68782 1 .007133 D

ATOM 12066 ND2ASND158 47059 31505-66517 1004124 D ATOM 12139 N LEU D 168 42170 50667-69035 1 004534 D

ATOM 12067 C ASN D 158 46015 32764-62563 1003849 D ATOM 12140 CA LEU D 168 4212649902 -67808 1004534 D

ATOM 12068 0 ASN D 158 4482332902-62843 1003849 D ATOM 12141 CB LEU D 168 4066449556 -67530 1006306 D

ATOM 12069 N TYR D 159 46761 33750-62073 1003840 D ATOM 12142 CG LEU D 168 39667 50584 -68093 1006306 D

ATOM 12070 CA TYRD 159 46215 35092-61899 1003840 D ATOM 12143 CDl LEU D 168 3825050098 -67904 1006306 D 65251/C766

ATOM 12144 CD2 LEU D 168 39863 51912 -67403 1006306 D ATOM 12229 C TYR D 177 42802 19670-63022 1002841 D ATOM 12145 C LEUD168 4296448629-67813 1004534 D ATOM 12230 O TYR D 177 41898 19430 63808 1002841 D

ATOM 12146 O LEU D 168 43505 48208 68833 1004534 D ATOM 12231 N ASN D 178 44036 19212-63200 1004618 D

ATOM 12147 N TYR D 169 4306248025 -66638 1004374 D ATOM 12232 CA ASN D 178 44381 18459-64397 1004618 D

ATOM 12148 CA TYR D 169 4380046787 -66471 1004374 D ATOM 12233 CB ASN D 178 43535 17201-64553 1004719 D

ATOM 12149 CB TYR D 169 4474446878 -65273 1005805 D ATOM 12234 CG ASN D 178 43958 16090-63616 1003966 D

ATOM 12150 CG TYR D 169 45911 47813-65455 1005805 D ATOM 12235 ODl ASN D 178 45007 16167 62961 1003966

ATOM 12151 CDl TYR D 169 4574749191 -65358 1005805 D D

ATOM 12152 CEl TYRD 169 46821 50051 -65528 1005805 D ATOM 12236 ND2 ASN D 178

ATOM 12153 CD2TYRD169 47187 47313 65729 1005805 D D ATOM 12154 CE2 TYR D 169 48270 48159-65901 1005805 D ATOM 12237 C ASN D 178 44032 19433-65500 1004618 D

ATOM 12155 CZ TYR D 169 48084 49530 -65800 1005805 D ATOM 12238 O ASN D 178 44343 20618 -65395 1004618 D

ATOM 12156 OH TYRD 169 49173 50360-65970 1005805 D ATOM 12239 N ASP D 179 43379 18958-66552 1003534 D

ATOM 12157 C TYR D 169 4278245677-66225 1004374 D ATOM 12240 CA ASP D 179 43002 19864-67629 1003534 D

ATOM 12158 0 TYR D 169 4198945757-65288 1004374 D ATOM 12241 CB ASP D 179 43185 19192-69004 1003501 D

ATOM 12159 N ASP D 170 42783 44656-67073 1004552 D ATOM 12242 CG ASPD 179 42475 17855-69123 1003896 D

ATOM 12160 CA ASP D 170 41852 43564 -66880 1004552 D ATOM 12243 ODl ASP D 179 41787 17431 -68170 1003896 D

ATOM 12161 CB ASP D 170 4149842905-68211 1007294 D ATOM 12244 OD2ASPD179 42611 17216-70189 1003896 D

ATOM 12162 CG ASP D 170 40239 43477-68824 1007294 D ATOM 12245 C ASPD 179 41571 20376-67474 1003534 D

ATOM 12163 ODl ASP D 170 39308 43795 68052 1007294 D ATOM 12246 O ASP D 179 41023 20957 -68389 1003534 D

ATOM 12164 OD2 ASP D 170 40182 43588 -70071 1007294 D ATOM 12247 N GLNDlSO 4098420170 -66298 1004196 D ATOM 12165 C ASP D 170 4246742531 -65962 1004552 D ATOM 12248 CA GLND 180 39614 20587-66017 1004196 D

ATOM 12166 O ASP D 170 4368842423 -65866 1004552 D ATOM 12249 CB GLND 180 38947 19570-65094 1005883 D

ATOM 12167 N GLY D 171 4162341776-65273 1004744 D ATOM 12250 CG GLN D 180 38991 18155-65579 1005046 D

ATOM 12168 CA GLY D 171 4214040748 -64394 1004744 D ATOM 12251 CD GLND 180 38333 18004-66921 1005046 D

ATOM 12169 C GLY D 171 41335 39468-64499 1004744 D ATOM 12252 OEl GLN D 180 39000 17914-67946 1005046

ATOM 121700 GLY D 171 40101 39511 -64525 1004744 D D

ATOM 12171 N VALD 172 42026 38332-64596 1003744 D ATOM 12253 NE2GLND180

ATOM 12172 CA VALD 172 41368 37030-64650 1003744 D D

ATOM 12173 CB VALD 172 41360 36387-66040 1006469 D ATOM 12254 C GLN D 180 39471 21972 -65368 1004196 D

ATOM 12174 CGl VAL D 172 40191 36883-66815 1005670 D ATOM 12255 O GLN D 180 39978 22209 -64270 1004196 D

ATOM 12175 CG2VALD172 42656 36667-66758 1005670 D ATOM 12256 N LEU D 181 3875922876-66033 1003716 D ATOM 12176 C VALD172 4211036070-63769 1003744 D ATOM 12257 CA LEUD 181 38531 24200-65476 1003716 D

ATOM 121770 VAL D 172 43299 36241 -63502 1003744 D ATOM 12258 CB LEU D 181 37873 25113 -66504 1005214 D

ATOM 12178 N PHE D 173 41391 35041 -63343 1003886 D ATOM 12259 CG LEUD 181 37491 26485-65942 1003957 D

ATOM 12179 CA PHED 173 41936 34000-62516 1003886 D ATOM 12260 CDl LEUDlSl 38735 27233 -65458 1003957 D

ATOM 12180 CB PHED 173 4153434207-61069 1006244 D ATOM 12261 CD2LEUD181 3675627283 -67005 1003957 D

ATOM 12181 CG PHED 173 41807 33020 60225 1004426 D ATOM 12262 C LEU D 181 37621 24047-64262 1003716 D

ATOM 12182 CDl PHE D 173 4310832713-59841 1004426 D ATOM 12263 O LEU D 181 3659023401-64341 1003716 D

ATOM 12183 CD2PHED173 40782 32136-59903 1004426 D ATOM 12264 N VAL D 182 3801024638 -63140 1003548 D

ATOM 12184 CEl PHED 173 43387 31543 59159 1004426 D ATOM 12265 CA VAL D 182 37225 24531 -61919 1003548 D

ATOM 12185 CE2 PHED 173 41049 30955-59217 1004426 D ATOM 12266 CB VALD 182 38103 24099 -60726 1005096 D

ATOM 12186 CZ PHE D 173 42353 30655-58845 1004426 D ATOM 12267 CGl VALD 182 37268 24068 -59461 1002944

ATOM 12187 C PHED173 4137732679-62985 1003886 D D

ATOM 12188 O PHE D 173 40181 32575-63246 1003886 D ATOM 12268 CG2VALD182 38719 22719-60995 1002944

ATOM 12189 N TYR D 174 4223531671-63098 1003888 D D

ATOM 12190 CA TYRD 174 41789 30341 -63495 1003888 D ATOM 12269 C VALD 182 3657725850 -61574 1003548 D

ATOM 12191 CB TYR D 174 42307 29958-64883 1005827 D ATOM 12270 O VALD 182 35422 25890 61 154 1003548 D

ATOM 12192 CG TYRD 174 41748 30775-66014 1004431 D ATOM 12271 N THR D 183 3732726933-61756 1004082 D

ATOM 12193 CDl TYRD 174 42526 31749-66637 1004431 D ATOM 12272 CA THRD 183 36839 28268-61438 1004082 D

ATOM 12194 CEl TYR D 174 42020 32523 -67687 1004431 D ATOM 12273 CB THR D 183 3719928664 59994 1005492 D

ATOM 12195 CD2 TYR D 174 40435 30585 -66466 1004431 D ATOM 12274 OGl THR D 183 3650627820-59077 1004151

ATOM 12196 CE2 TYR D 174 3991431356-67521 1004431 D D

ATOM 12197 CZ TYRD 174 40719 32323-68124 1004431 D ATOM 12275 CG2THRD 183 36825 30101 -59720 1004151

ATOM 12198 OH TYRD 174 40247 33090-69168 1004431 D D

ATOM 12199 C TYR D 174 4226429294-62496 1003888 D ATOM 12276 C THRD 183 37435 29333 -62329 1004082 D

ATOM 12200 O TYR D 174 4339629342 -62039 1003888 D ATOM 12277 O THR D 183 38618 29284-62655 1004082 D

ATOM 12201 N ASPD 175 4137728361-62163 1003924 D ATOM 12278 N LYS D 184 3660430285 -62737 1004043 D

ATOM 12202 CA ASP D 175 4166427258 -61259 1003924 D ATOM 12279 CA LYS D 184 3708831410-63513 1004043 D

ATOM 12203 CB ASP D 175 4063727222 -60122 1006775 D ATOM 12280 CB LYS D 184 36581 31400-64934 1004660 D

ATOM 12204 CG ASP D 175 4095426166 -59070 1005596 D ATOM 12281 CG LYS D 184 37062 32626 -65684 1003844 D

ATOM 12205 ODl ASP D 175 41502 25101 -59426 1005596 D ATOM 12282 CD LYS D 184 3649432716 -67082 1003844 D

ATOM 12206 OD2ASPD175 40638 26393 57881 1005596 D ATOM 12283 CE LYS D 184 36938 34002 -67750 1003844 D

ATOM 12207 C ASPD 175 41525 25995-62124 1003924 D ATOM 12284 NZ LYS D 184 3632734169 -69094 1003844 D

ATOM 12208 0 ASP D 175 4043425669-62597 1003924 D ATOM 12285 C LYSD 184 3657432663-62821 1004043 D

ATOM 12209 N HIS D 176 4262625292 -62350 1004720 D ATOM 12286 O LYSD 184 35403 32750 -62450 1004043 D ATOM 12210 CA HIS D 176 4258224083-63151 1004720 D ATOM 12287 N ILE D 185 3745933627 -62624 1005356 D

ATOM 12211 CB HIS D 176 43473 24224-64381 1007510 D ATOM 12288 CA ILED 185 37085 34868-61975 1005356 D

ATOM 12212 CG HIS D 176 4290025082 -65462 1004423 D ATOM 12289 CB ILED 185 37628 34926-60531 1005369 D

ATOM 12213 CD2 HIS D 176 43241 26322-65890 1004423 D ATOM 12290 CG2ILED185 37491 36341 -59965 1002261 D

ATOM 12214 NDl HIS D 176 4185924673 -66267 1004423 D ATOM 12291 CGl ILE D 185 36877 33916 -59654 1002261 D

ATOM 12215 CEl HIS D 176 4158425621 -67145 1004423 D ATOM 12292 CDl ILE D 185 37437 33759-58245 1002261 D

ATOM 12216 NE2 HIS D 176 4240726632 -66938 1004423 D ATOM 12293 C ILE D 185 37663 36019-62775 1005356 D

ATOM 12217 C HIS D 176 4303222838-62385 1004720 D ATOM 12294 O ILE D 185 3879035941 -63268 1005356 D

ATOM 12218 O HIS D 176 44113 22828-61788 1004720 D ATOM 12295 N SERD 186 36884 37081 -62934 I 003432 D

ATOM 12219 N TYR D 177 42191 21799-62392 1002841 D ATOM 12296 CA SER D 186 37363 38240-63666 1003432 D

ATOM 12220 CA TYRD 177 42531 20522-61783 1002841 D ATOM 12297 CB SERD 186 36830 38229 -65097 1005584 D ATOM 12221 CB TYR D 177 41365 19937-61011 1004701 D ATOM 12298 OG SER D 186 35463 37913 -65102 1004495 D

ATOM 12222 CG TYR D 177 41696 18576 60474 1004002 D ATOM 12299 C SER D 186 36989 39527 -62937 1003432 D

ATOM 12223 CDl TYRD 177 42641 18422-59463 1004002 D ATOM 12300 O SER D 186 36008 39594 -62193 1003432 D

ATOM 12224 CEl TYRD 177 42992 17167-58992 1004002 D ATOM 12301 N TYRD 187 3781740541-63125 1004886 D

ATOM 12225 CD2TYRD 177 41102 17435-61002 1004002 D ATOM 12302 CA TYR D 187 3761041823 62486 1004886 D

ATOM 12226 CE2TYRD177 41440 16176-60539 1004002 D ATOM 12303 CB TYR D 187 3889442625 62533 1008931 D

ATOM 12227 CZ TYR D 177 42390 16047 -59532 1004002 D ATOM 12304 CG TYR D 187 3878743906 -61774 1004352 D

ATOM 12228 OH TYR D 177 42729 14793-59075 1004002 D 65251/C766

ATOM 12305 CDl TYRD 187 38743 43903-60390 1004352 D ATOM 12390 CG ASN D 197 33585 35429-64910 1004810 D ATOM 12306 CEl TYR D 187 3866445088-59670 1004352 D ATOM 12391 ODl ASN D 197 32908 36357-64462 1004810

ATOM 12307 CD2 TYR D 187 38740 45131 -62435 1004352 D D

ATOM 12308 CE2 TYR D 187 3866046322-61725 1004352 D ATOM 12392 ND2 ASN D 197 34 i 35553 65181 1004810

ATOM 12309 CZ TYRD 187 38625 46293-60340 1004352 D D

ATOM 12310 OH TYR D 187 38572 47467-59622 1004352 D ATOM 12393 C ASN D 197 3181232102-64260 1004678 D

ATOM 12311 C TYRD187 3650442621 -63160 1004886 D ATOM 12394 O ASN D 197 3080031774 -64860 1004678 D

ATOM 12312 O TYRD 187 36583 42949-64347 1004886 D ATOM 12395 N PHE D 198 32689 31227-63785 1004156 D

ATOM 12313 N ASN D 188 3548042939-62386 1004779 D ATOM 12396 CA PHED 198 3250629804 -63976 1004156 D

ATOM 12314 CA ASN D 188 34343 43709-62862 1004779 D ATOM 12397 CB PHED 198 3338029327 -65126 1003564 D ATOM 12315 CB ASN D 188 3313643361 -62008 10018483 D ATOM 12398 CG PHED 198 3322827882 -65429 1003564 D

ATOM 12316 CG ASN D 188 31912 44090-62427 1004586 D ATOM 12399 CDl PHE D 198 32295 27450 -66353 1003564 D

ATOM 12317 ODl ASND 188 31928 45298-62590 1004586 D ATOM 12400 CD2PHED198 3398726940 -64751 1003564 D

ATOM 12318 ND2 ASN D 188 30833 43367-62606 1004586 D ATOM 12401 CEl PHED 198 32115 26094-66594 1003564 D

ATOM 12319 C ASN D 188 3465945216-62745 1004779 D ATOM 12402 CE2PHED 198 33811 25577-64989 1003564 D

ATOM 12320 O ASN D 188 3475445751 -61636 1004779 D ATOM 12403 CZ PHED 198 32875 25156-65908 1003564 D

ATOM 12321 N HIS D 189 34816 45905-63876 1004242 D ATOM 12404 C PHE D 198 3286229010-62743 1004156 D

ATOM 12322 CA HIS D 189 3514847326-63848 1004242 D ATOM 12405 O PHE D 198 3378629369 -62009 1004156 D

ATOM 12323 CB HIS D 189 3556847765-65233 1009740 D ATOM 12406 N ARG D 199 32121 27929-62524 1004389 D

ATOM 12324 CG HIS D 189 3690647243-65614 1005794 D ATOM 12407 CA ARG D 199 3237627038 61411 1004389 D

ATOM 12325 CD2 HIS D 189 3726646181-66371 1005794 D ATOM 12408 CB ARGD 199 31590 27453-60177 1004828 D ATOM 12326 NDl HIS D 189 38075 47787-65132 1005794 D ATOM 12409 CG ARG D 199 3182926507-59033 1004828 D

ATOM 12327 CEl HIS D 189 3910047083-65579 1005794 D ATOM 12410 CD ARG D 199 33203 26721 -58427 1004828 D

ATOM 12328 NE2 HIS D 189 38636 46102-66333 1005794 D ATOM 12411 NE ARG D 199 33077 27527 -57223 1004828 D

ATOM 12329 C HIS D 189 34060 48234-63303 1004242 D ATOM 12412 CZ ARGD 199 33942 28456 -56856 1004828 D

ATOM 12330 O HIS D 189 34347 49293-62759 1004242 D ATOM 12413 NHl ARG D 199 35001 28695 -57605 1004828

ATOM 12331 N GLU D 190 32811 47813-63444 1006635 D D

ATOM 12332 CA GLU D 190 31681 48591 -62962 1006635 D ATOM 12414 NH2 ARG D 199 3374229162 -55747 1004828

ATOM 12333 CB GLU D 190 30389 47992-63515 10012249 D D

ATOM 12334 CG GLU D 190 2921948938-63578 1009691 D ATOM 12415 C ARG D 199 3196425637 61836 1004389 D

ATOM 12335 CD GLU D 190 28018 48300-64246 1009691 D ATOM 12416 0 ARG D 199 3081025402-62163 1004389 D

ATOM 12336 OEl GLU D 190 2747047333-63676 1009691 D ATOM 12417 N ALAD200 3290924709-61851 1004210 D ATOM 12337 OE2 GLU D 190 2762748754-65347 1009691 D ATOM 12418 CA ALA D 200 32597 23341 -62236 1004210 D

ATOM 12338 C GLU D 190 3169448521 -61432 1006635 D ATOM 12419 CB ALA D 200 3385722471 -62167 1005377 D

ATOM 12339 O GLU D 190 3173849530 60746 1006635 D ATOM 12420 C ALAD200 3150622775-61319 1004210 D

ATOM 12340 N THR D 191 3I 6884730S-60907 1005153 D ATOM 12421 0 ALAD200 3153822951 -60098 1004210 D

ATOM 12341 CA THR D 191 3169047056-59472 1005153 D ATOM 12422 N ASP D 201 30539 22099-61928 1004743 D

ATOM 12342 CB THR D 191 3124745631 -59193 1006406 D ATOM 12423 CA ASP D 201 29422 21493-61218 1004743 D

ATOM 12343 OGl THR D 191 2990745459-59649 1006406 D ATOM 12424 CB ASP D 201 2849420822-62229 10010104 D

ATOM 12344 CG2 THR D 191 3128345348-57737 1006406 D ATOM 12425 CG ASP D 201 29249 19906-63193 10010104 D

ATOM 12345 C THR D 191 3303047264-58765 1005153 D ATOM 12426 ODl ASP D 201 30037 20431-64016 10010104

ATOM 12346 O THRD191 3306947570-57578 1005153 D D

ATOM 12347 N ARG D 192 34131 47071 -59480 1007264 D ATOM 12427 OD2ASPD201 29062 18665-63124 10010104

ATOM 12348 CA ARG D 192 3546947248-58909 1007264 D D

ATOM 12349 CB ARG D 192 3555948578-58152 100131 19 D ATOM 12428 C ASP D 201 29842 20465 60166 1004743 D

ATOM 12350 CG ARG D 192 3543549792-59047 100131 19 D ATOM 12429 0 ASP D 201 29140 20279-59178 1004743 D

ATOM 12351 CD ARG D 192 36501 49764-60142 10013119 D ATOM 12430 N TRP D 202 30977 19801 -60368 1005349 D

ATOM 12352 NE ARGD192 36301 50808-61 145 100131 19 D ATOM 12431 CA TRP D 202 31426 18780-59428 1005349 D

ATOM 12353 CZ ARG D 192 36372 52113-60895 10013119 D ATOM 12432 CB TRPD202 32245 17713-60154 1004110 D

ATOM 12354 NHl ARG D 192 36641 52547-59670 10013119 D ATOM 12433 CG TRP D 202 33402 18243-60956 10041 10 D

ATOM 12355 NH2 ARG D 192 36166 52987-61871 10013119 D ATOM 12434 CD2 TRP D 202 34734 18482-60487 1004110 D

ATOM 12356 C ARG D 192 35943 46103-58008 1007264 D ATOM 12435 CE2 TRP D 202 35489 18926-61591 1004110 D

ATOM 12357 O ARG D 192 3672846310-57092 1007264 D ATOM 12436 CE3 TRP D 202 35362 18360-59239 1004110 D

ATOM 12358 N HIS D 193 3545744896-58278 1005771 D ATOM 12437 CDl TRP D 202 33406 18553-62284 1004110 D

ATOM 12359 CA HIS D 193 35861 43711 -57535 1005771 D ATOM 12438 NEl TRP D 202 34653 18958-62676 1004110 D

ATOM 12360 CB HIS D 193 3506443601-56235 10011934 D ATOM 12439 CZ2 TRP D 202 36841 19247-61488 1004110 D

ATOM 12361 CG HIS D 193 33635 43201 56420 10011934 D ATOM 12440 CZ3 TRP D 202 36703 18679-59138 1004110 D

ATOM 12362 CD2 HIS D 193 3298442620-57460 10011934 D ATOM 12441 CH2 TRP D 202 37429 19117-60258 1004110 D

ATOM 12363 NDl HISD 193 3270343338-55416 10011934 D ATOM 12442 C TRPD202 32233 19267-58240 1005349 D

ATOM 12364 CEl HIS D 193 31543 42859 55829 10011934 D ATOM 12443 0 TRP D 202 32522 18492-57328 1005349 D

ATOM 12365 NE2 HIS D 193 3168442417-57065 10011934 D ATOM 12444 N PHE D 203 32593 20542-58243 1004186 D

ATOM 12366 C HIS D 193 35655 42501 -58451 1005771 D ATOM 12445 CA PHE D 203 3340421092-57169 1004186 D

ATOM 12367 O HIS D 193 3504442635-59512 1005771 D ATOM 12446 CB PHE D 203 3448721996 -57776 1004090 D

ATOM 12368 N GLY D 194 3615641331 -58066 1003714 D ATOM 12447 CG PHE D 203 35513 22465 56794 1004090 D

ATOM 12369 CA GLYD 194 36022 40155-58923 1003714 D ATOM 12448 CDl PHE D 203 36429 21570-56236 1004090 D

ATOM 12370 C GLY D 194 3467039462-58907 1003714 D ATOM 12449 CD2 PHE D 203 35573 23794-56427 1004090 D ATOM 12371 O GLY D 194 33875 39663-58000 1003714 D ATOM 12450 CEl PHE D 203 3740222003-55321 1004090 D

ATOM 12372 N ASN D 195 3438938659-59924 1004086 D ATOM 12451 CE2PHED203 36532 24238-55517 1004090 D

ATOM 12373 CA ASND 195 33131 37931-59982 1004086 D ATOM 12452 CZ PHE D 203 3744923339 -54964 I 004090 D

ATOM 12374 CB ASN D 195 32149 38557-60982 1007065 D ATOM 12453 C PHE D 203 32605 21871-56127 1004186 D

ATOM 12375 CG ASND 195 31599 39881-60523 1007065 D ATOM 12454 O PHE D 203 3213622974-56407 1004186 D

ATOM 12376 ODl ASN D 195 31225 40045-59369 1007065 D ATOM 12455 N ASN D 204 3243421289-54937 1004541 D

ATOM 12377 ND2 ASN D 195 3152940835-61437 1007065 D ATOM 12456 CA ASN D 204 31731 21962-53842 1004541 D

ATOM 12378 C ASN D 195 3345036539-60473 1004086 D ATOM 12457 CB ASN D 204 30953 20960-52966 1007383 D

ATOM 12379 O ASN D 195 3430736367-61350 1004086 D ATOM 12458 CG ASN D 204 3043621591 -51675 1007383 D

ATOM 12380 N VALD 196 3277435537 59922 1004178 D ATOM 12459 ODl ASN D 204 31225 22001 -50833 1007383

ATOM 12381 CA VALD 196 32998 34181-60387 1004178 D D ATOM 12382 CB VALD 196 3253733159-59365 1003968 D ATOM 12460 ND2 ASN D 204 29121 21712-51525 1007383

ATOM 12383 CGl VAL D 196 3271731756-59930 1003968 D D

ATOM 12384 CG2 VAL D 196 33323 33328-58082 1003968 D ATOM 12461 C ASN D 204 3286622613-53051 1004541 D

ATOM 12385 C VALD 196 32169 34017-61650 1004178 D ATOM 12462 O ASN D 204 33567 21951-52284 1004541 D

ATOM 12386 O VALD196 30950 34170-61618 1004178 D ATOM 12463 N ILE D 205 33061 23910-53256 1004471 D

ATOM 12387 N ASN D 197 3282833728-62764 1004678 D ATOM 12464 CA ILE D 205 3414924618-52594 1004471 D

ATOM 12388 CA ASN D 197 32123 33557-64024 1004678 D ATOM 12465 CB ILE D 205 3418726102-53020 1004567 D

ATOM 12389 CB ASN D 197 3296734068 65189 1004810 D ATOM 12466 CG2 ILE D 205 3318026901 -52227 1004567 D 65251/C766

ATOM 12467 CGl ILE D 205 35583 26671 -52786 1004567 D ATOM 12552 CE2TYRD216 40433 28790-56283 1003583 D ATOM 12468 CDl ILE D 205 3585827920 -53580 1004567 D ATOM 12553 CZ TYR D 216 39061 28860-56463 I 003583 D ATOM 12469 C ILE D 205 3411624534-51076 1004471 D ATOM 12554 OH TYR D 216 38365 27734-56815 1003583 D ATOM 12470 O ILE D 205 35110 24818-50419 1004471 D ATOM 12555 C TYR D 216 41783 34221-53810 1003596 D ATOM 12471 N SER D 206 32975 24151 -50518 1006132 D ATOM 12556 O TYR D 216 4280834449 -54462 1003596 D ATOM 12472 CA SER D 206 32855 24024 -49071 1006132 D ATOM 12557 N ASN D 217 41332 35042 -52865 1 003522 D ATOM 12473 CB SER D 206 3138623972-48664 1006912 D ATOM 12558 CA ASN D 217 42012 36298-52579 1003522 D ATOM 12474 OG SER D 206 30751 25198-48974 1006912 D ATOM 12559 CB ASN D 217 4337936041 -51948 1004636 D ATOM 12475 C SER D 206 33561 22765 -48593 1006132 D ATOM 12560 CG ASN D 217 4328235284 -50644 1004109 D ATOM 12476 O SER D 206 33925 22653 47430 1006132 D ATOM 12561 ODl ASN D 217 43881 34225-50488 1004109 ATOM 12477 N ARG D 207 33748 21815-49502 1005439 D D ATOM 12478 CA ARG D 207 3441820576 -49170 1005439 D ATOM 12562 ND2 ASN D 217 42528 3582549698 1004109 ATOM 12479 CB ARC D 207 33808 19422 -49955 1005741 D D ATOM 12480 CG ARG D 207 32455 18996-49430 1005741 D ATOM 12563 C ASN D 217 4220037073-53875 1003522 D ATOM 12481 CD ARG D 207 32233 17514-49638 1005741 D ATOM 12564 O ASN D 217 4322637726 -54071 1003522 D ATOM 12482 NE ARG D 207 31910 17182-51024 1005741 D ATOM 12565 N PHED218 4120437004-54756 1003893 D ATOM 12483 CZ ARG D 207 32149 15996-51587 1005741 D ATOM 12566 CA PHE D 218 4129037684-56036 1003893 D ATOM 12484 NHl ARG D 207 32726 15025-50887 1005741 D ATOM 12567 CB PHE D 218 40079 37392-56897 1003926 D ATOM 12485 NH2 ARG D 207 31796 15768-52847 1005741 D ATOM 12568 CG PHE D 218 40175 38002 -58244 1003578 D ATOM 12486 C ARG D 207 35922 20650 -49428 1005439 D ATOM 12569 CD1 PHED218 40853 37348-59256 1003578 D ATOM 12487 O ARG D 207 36614 19635-49372 1005439 D ATOM 12570 CD2 PHE D 218 39636 39260-58495 1003578 D ATOM 12488 N SER D 208 36422 21851 -49711 1004780 D ATOM 12571 CE1 PHED218 41002 37931 -60521 1003578 D ATOM 12489 CA SER D 208 37843 22038 -49957 1004780 D ATOM 12572 CE2PHED218 39775 39850-59737 1003578 D ATOM 12490 CB SER D 208 38099 22364-51419 1005684 D ATOM 12573 CZ PHE D 218 40463 39179-60759 1003578 D ATOM 12491 OG SER D 208 3949722448 -51646 1005684 D ATOM 12574 C PHED218 41448 39196-55941 1003893 D ATOM 12492 C SER D 208 3839023159-49088 1004780 D ATOM 12575 O PHE D 218 42332 39769-56580 1003893 D ATOM 12493 O SER D 208 387102424049573 1004780 D ATOM 12576 N ASN D 219 4058939847 -55166 1004493 D ATOM 12494 N PRO D 209 3850622901 -47783 1004206 D ATOM 12577 CA ASN D 219 40701 41290 -55047 1004493 D ATOM 12495 CD PRO D 209 38215 21575 -47219 1004145 D ATOM 12578 CB ASN D 219 39653 41836 -54088 1004554 D ATOM 12496 CA PRO D 209 3899723806 -46742 1004206 D ATOM 12579 CG ASND219 3825441495-54516 1003717 D ATOM 12497 CB PRO D 209 3919422883-45552 1004145 D ATOM 12580 ODl ASN D 219 3794041481 -55698 1003717 ATOM 12498 CG PRO D 209 3812821877-45748 1004145 D D ATOM 12499 C PRO D 209 40283 24525 -47092 1004206 D ATOM 12581 ND2 ASN D 219 3739841226-53551 1003717 ATOM 12500 O PRO D 209 4051525637 -46624 1004206 D D ATOM 12501 N HISD210 4111423902-47923 1005659 D ATOM 12582 C ASN D 219 42101 41679 -54583 1004493 D ATOM 12502 CA HIS D 210 42392 2449848269 I 005659 D ATOM 12583 O ASND219 4270742617 55114 1004493 D ATOM 12503 CB HIS D 210 4345723412-48227 1005944 D ATOM 12584 N PHE D 220 4261740952 -53596 1003766 D ATOM 12504 CG HIS D 210 4362422812 -46865 1005944 D ATOM 12585 CA PHE D 220 4395641223-53091 1003766 D ATOM 12505 CD2HISD210 4325021609 -46366 1005944 D ATOM 12586 CB PHE D 220 44333 40231-52010 1004426 D ATOM 12506 NDl HIS D 210 4417523508-45810 1005944 D ATOM 12587 CG PHE D 220 4579240258 -51666 1003724 D ATOM 12507 CEl HIS D 210 44133 22762 -44720 1005944 D ATOM 12588 CDl PHE D 220 4628941186-50761 1003724 D ATOM 12508 NE2HISD210 43575 21605 -45030 1005944 D ATOM 12589 CD2 PHE D 220 46684 39375-52287 1003724 D ATOM 12509 C HIS D 210 42454 25308 -49561 1005659 D ATOM 12590 CEI PHE D 220 4764741246 -50476 1003724 D ATOM 12510 O HIS D 210 43524 2574349986 1005659 D ATOM 12591 CE2 PHE D 220 48051 39424-52010 1003724 D ATOM 12511 N THR D 211 41303 25516-50186 1004027 D ATOM 12592 CZ PHE D 220 4853240365-51101 1003724 D ATOM 12512 CA THRD211 41243 26342-51375 1004027 D ATOM 12593 C PHE D 220 4500241144 -54194 1003766 D ATOM 12513 CB THR D 211 40021 26005-52238 1005051 D ATOM 12594 O PHE D 220 4576442075 -54401 1003766 D ATOM 12514 OG1 THRD211 40121 24649-52691 1005051 D ATOM 12595 N TRP D 221 4504440021 -54895 1003742 D ATOM 12515 CG2THRD21I 39949 26935-53439 1005051 D ATOM 12596 CA TRP D 221 4601439842 -55966 1003742 D ATOM 12516 C THR D 211 41051 27716-50757 1004027 D ATOM 12597 CB TRP D 221 4599038388-56461 1004713 D ATOM 12517 O THR D 211 4014627903 -49938 I 004027 D ATOM 12598 CG TRP D 221 4660637431 -55485 1004028 D ATOM 12518 N PRO D 212 41901 28690-51119 1004943 D ATOM 12599 CD2TRPD221 47963 37437-55031 1004028 D ATOM 12519 CD PRO D 212 4294628558 -52147 1004728 D ATOM 12600 CE2TRPD221 48090 36407-54080 1004028 D ATOM 12520 CA PRO D 212 4184630067 50600 1004943 D ATOM 12601 CE3TRPD221 49086 38218-55338 1004028 D ATOM 12521 CB PRO D 212 42797 30815-51522 1004728 D ATOM 12602 CDl TRP D 221 4598236422-54811 1004028 D ATOM 12522 CG PRO D 212 43799 29768 -51878 1004728 D ATOM 12603 NEl TRP D 221 46866 35804-53963 1004028 D ATOM 12523 C PRO D 212 40449 30709 -50569 1004943 D ATOM 12604 CZ2TRPD221 49297 36133-53429 1004028 D ATOM 12524 O PRO D 212 39662 30550 -51505 004943 D ATOM 12605 CZ3TRPD221 50290 37943 54689 1004028 D ATOM 12525 N GLY D 213 401483143949496 004292 D ATOM 12606 CH2TRPD221 50383 36909 -53744 1004028 D ATOM 12526 CA GLY D 213 38852 32095 -49369 1004292 D ATOM 12607 C TRP D 221 45820 40802 -57143 1003742 D ATOM 12527 C GLY D 213 3881433432 -50079 1004292 D ATOM 12608 O TRP D 221 4677641423 -57623 1003742 D ATOM 12528 O GLYD213 39813 33839-50675 1004292 D ATOM 12609 N TYR D 222 4458740934-57613 1004404 D ATOM 12529 N ASN D 214 3768034126-50016 1005018 D ATOM 12610 CA TYR D 222 44335 41816-58740 1004404 D ATOM 12530 CA ASN D 214 37516 35435-50684 1005018 D ATOM 12611 CB TYR D 222 4283241993-58958 1004057 D ATOM 12531 CB ASN D 214 38513 36476-50186 10015026 D ATOM 12612 CG TYR D 222 42536 43079 -59949 1003914 D ATOM 12532 CG ASN D 214 38804 3631748760 10014443 D ATOM 12613 CDl TYR D 222 4269742856-61314 1003914 ATOM 12533 ODl ASN D 214 38093 3558348083 10014443 D D ATOM 12534 ND2ASND214 39826 3700548259 10014443 D ATOM 12614 CEl TYR D 222 42525 43881 -62228 1003914 D ATOM 12535 C ASN D 214 3778035247-52154 1005018 D ATOM 12615 CD2TYRD222 4218644358-59518 1003914 ATOM 12536 O ASN D 214 3857035981 52744 1005018 D D ATOM 12537 N ASP D 215 3712634260-52741 1004109 D ATOM 12616 CE2 TYR D 222 42015 45392-60425 1003914 D ATOM 12538 CA ASP D 215 37321 33972-54149 1004109 D ATOM 12617 CZ TYR D 222 4218745146-61777 1003914 D ATOM 12539 CB ASP D 215 36573 34987-54996 10015859 D ATOM 12618 OH TYR D 222 42039 46161-62683 1003914 D ATOM 12540 CG ASP D 215 35113 35043-54651 1007997 D ATOM 12619 C TYR D 222 4496643175-58464 1004404 D ATOM 12541 ODl ASP D 215 34455 33979 -54702 I 007997 D ATOM 126200 TYR D 222 45753 43709-59245 1004404 D ATOM 12542 OD2 ASP D 215 3462436143 -54321 1007997 D ATOM 12621 N SER D 223 4460643722-57321 1004313 D ATOM 12543 C ASP D 215 3880434002-54471 1004109 D ATOM 12622 CA SER D 223 4509645013 56927 1004313 D ATOM 12544 O ASP D 215 3925934845 -55233 1004109 D ATOM 12623 CB SER D 223 4444745407 -55620 1003660 D ATOM 12545 N TYRD216 39545 33086 -53848 1003596 D ATOM 12624 OG SER D 223 4497946637 -55197 1003522 D ATOM 12546 CA TYR D 216 40985 32942 -54047 1003596 D ATOM 12625 C SERD 223 46613 45097-56808 1004313 D ATOM 12547 CB TYR D 216 41259 32424 -55461 1005708 D ATOM 12626 O SER D 223 4723445996-57382 1004313 D ATOM 12548 CG TYR D 216 40490 31174-55813 1003583 D ATOM 12627 N LEU D 224 4721044163-56069 1003228 D ATOM 12549 CDl TYR D 216 3911431205-55999 1003583 D ATOM 12628 CA LEU D 224 48653 44156-55879 1003228 D ATOM 12550 CEl TYR D 216 3839630055 -56320 1003583 D ATOM 12629 CB LEU D 224 4903543132 -54827 1006669 D ATOM 12551 CD2TYRD216 41140 29949 -55957 1003583 D ATOM 12630 CG LEU D 224 50533 43073-54545 1004393 D 65251/C766

ATOM 12631 CDI LEU D 224 5106944456-54151 1004393 D ATOM 12716 NZ LYS D 234 55307 55091 -60238 : I 007461 D ATOM 12632 CD2 LEU D 224 5077642071-53431 1004393 D ATOM 12717 C LYS D 234 59218 52813 66259 10010706 D

ATOM 12633 C LEU D 224 4941243876 57169 1003228 D ATOM 12718 O LYS D 234 5954653726-67017 10010706 D

ATOM 12634 O LEU D 224 50529 44344 -57360 1003228 D ATOM 12719 N ASN D 235 6002051785-65993 1 009368 D

ATOM 12635 N MET D 225 48806 43112 -58066 1004393 D ATOM 12720 CA ASN D 235 61306 51667-66677 1009368 D

ATOM 12636 CA MET D 225 4945942822-59329 1004393 D ATOM 12721 CB ASN D 235 62215 50636-65993 1009929 D

ATOM 12637 CB MET D 225 4882741604-59979 1007638 D ATOM 12722 CG ASN D 235 63510 50387-66770 1009929 D

ATOM 12638 CG MET D 225 4912040335-59227 1004510 D ATOM 12723 ODl ASN D 235 63490 50274 -67995 1009929

ATOM 12639 SD MET D 225 48529 38924-60114 1004510 D D

ATOM 12640 CE MET D 225 49558 38970-61568 1004510 D ATOM 12724 ND2ASND235 64627 50275 66054 1009929 ATOM 12641 C MET D 225 4933044029-60237 1004393 D D

ATOM 12642 O MET D 225 50226 44339-61021 1004393 D ATOM 12725 C ASN D 235 60882 51159-68053 1009368 D

ATOM 12643 N LYS D 226 4820044716-60125 1005686 D ATOM 12726 O ASN D 235 6046050017 68193 1009368 D

ATOM 12644 CA LYS D 226 47981 45897-60932 1005686 D ATOM 12727 N ASP D 236 60983 52011 69063 10012448 D

ATOM 12645 CB LYS D 226 4661646498-60626 10010321 D ATOM 12728 CA ASP D 236 60559 51652-70411 10012448 D

ATOM 12646 CG LYS D 226 4630947738-61429 1005467 D ATOM 12729 CB ASP D 236 60716 52868-71330 10013531 D

ATOM 12647 CD LYS D 226 4501648360-60960 1005467 D ATOM 12730 CG ASP D 236 59780 52822 -72523 10013531 D

ATOM 12648 CE LYS D 226 44815 49735-61567 1005467 D ATOM 12731 ODl ASP D 236 59995 51986-73425 10013531

ATOM 12649 NZ LYS D 226 43553 50355 61070 1005467 D D

ATOM 12650 C LYS D 226 49088 46872 -60562 1005686 D ATOM 12732 OD2ASPD236 58820 53622 -72554 10013531

ATOM 12651 O LYSD226 4974747438-61428 1005686 D D ATOM 12652 N GLU D 227 49303 47043 -59261 1006867 D ATOM 12733 C ASP D 236 61239 50429 -71044 10012448 D

ATOM 12653 CA GLU D 227 5033747944 -58762 1006867 D ATOM 12734 O ASP D 236 60841 49988-72122 10012448 D

ATOM 12654 CB GLU D 227 5039547898-57234 10012079 D ATOM 12735 N SER D 237 62251 49873-70385 1009361 D

ATOM 12655 CG GLU D 227 51361 48901 -56632 1009659 D ATOM 12736 CA SER D 237 6294048707 -70936 1009361 D

ATOM 12656 CD GLU D 227 5166448631 -55166 1009659 D ATOM 12737 CB SER D 237 6443848767 -70615 10011289 D

ATOM 12657 OEl GLU D 227 5071248499-54363 1009659 D ATOM 12738 OG SER D 237 64688 48461-69254 10011289 D

ATOM 12658 OE2 GLU D 227 52863 48560-54815 1009659 D ATOM 12739 C SER D 237 6235747401 -70397 1009361 D

ATOM 12659 C GLU D 227 51691 47534-59324 1006867 D ATOM 12740 O SER D 237 6285846315-70698 1009361 D

ATOM 12660 O GLU D 227 5243948361 -59839 1006867 D ATOM 12741 N THR D 238 6129947514 69597 10010149 D

ATOM 12661 N THR D 228 5199646245-59230 1005196 D ATOM 12742 CA THR D 238 60642 46346 -69015 10010149

ATOM 12662 CA THR D 228 5326645727-59715 1005196 D D ATOM 12663 CB THR D 228 5338844231-59428 1005777 D ATOM 12743 CB THR D 238 60677 46382-67467 10010494 D

ATOM 12664 OGl THR D 228 5326844015-58018 1004376 D ATOM 12744 OGl THR D 238 61991 46740-67025 10010494

ATOM 12665 CG2 THR D 228 5473643704-59922 1004376 D D

ATOM 12666 C THR D 228 5346645948-61205 1005196 D ATOM 12745 CG2THRD238 60321 45014-66889 10010494

ATOM 12667 0 THRD228 5456746258-61653 1005196 D D

ATOM 12668 N LEU D 229 52401 45777 61978 1006119 D ATOM 12746 C THR D 238 59185 46308-69450 1 0010149 D

ATOM 12669 CA LEU D 229 5250745959-63412 1006119 D ATOM 12747 O THR D 238 5857645243 69491 10010149 D

ATOM 12670 CB LEU D 229 5121745510-64091 1006597 D ATOM 12748 N LYS D 239 58643 47480-69771 1 009200 D

ATOM 12671 CG LEU D 229 5119045624-65615 1003785 D ATOM 12749 CA LYS D 239 5725647629-70199 1009200 D

ATOM 12672 CDl LEU D 229 5249445111 -66209 1003785 D ATOM 12750 CB LYS D 239 5715448741 -71246 1009870 D

ATOM 12673 CD2 LEU D 229 5000244841 -66154 1003785 D ATOM 12751 CG LYS D 239 55735 49036-71703 1009870 D

ATOM 12674 C LEU D 229 52815 47418 63737 10061 19 D ATOM 12752 CD LYS D 239 55678 50303 -72540 1009870 D

ATOM 12675 O LEU D 229 5363247703 64604 1006119 D ATOM 12753 CE LYS D 239 56086 51518-71722 1009870 D

ATOM 12676 N GLU D 230 5217448339-63027 1007080 D ATOM 12754 NZ LYS D 239 56027 52767 -72527 I 009870 D

ATOM 12677 CA GLU D 230 52402 49761 -63246 1007080 D ATOM 12755 C LYS D 239 5667246328 -70748 1009200 D

ATOM 12678 CB GLU D 230 51480 50591 -62353 10015674 D ATOM 12756 O LYS D 239 5720445746-71696 1009200 D

ATOM 12679 CG GLU D 230 50020 50519-62768 10012120 D ATOM 12757 N THR D 240 5557745876-70137 1 007170 D

ATOM 12680 CD GLU D 230 49117 51383 -61906 10012120 D ATOM 12758 CA THR D 240 54925 44637-70539 1007170 D

ATOM 12681 OE1 GLUD230 49425 52581 -61743 10012120 D ATOM 12759 CB THR D 240 5519843508-69528 10010640 D

ATOM 12682 OE2GLUD230 48095 50874-61398 10012120 D ATOM 12760 OGl THR D 240 56609 43376 -69325 10010640

ATOM 12683 C GLU D 230 53858 50127-62983 1007080 D D

ATOM 12684 O GLU D 230 54485 50806 -63793 1007080 D ATOM 12761 CG2THRD240 54643 42186 70046 10010640

ATOM 12685 N GLU D 231 5440049672-61857 1007346 D D

ATOM 12686 CA GLU D 231 5579449947-61509 1007346 D ATOM 12762 C THRD240 5341744789-70661 1007170 D

ATOM 12687 CB GLU D 231 5613449320-60155 10015878 D ATOM 12763 O THR D 240 5280845649 -70024 I 007170 D

ATOM 12688 CG GLU D 231 55219 49747-59025 10013502 D ATOM 12764 N THR D 241 52833 43927 -71485 1005948 D

ATOM 12689 CD GLU D 231 55364 51211-58675 10013502 D ATOM 12765 CA THR D 241 51401 43899-71729 1005948 D

ATOM 12690 OEl GLU D231 55229 52062-59581 10013502 D ATOM 12766 CB THR D 241 5107042950 -72886 10010688 D

ATOM 12691 OE2 GLU D 231 55609 51510-57487 10013502 D ATOM 12767 OGl THR D 241 51925 43233 73998 1006658

ATOM 12692 C GLUD231 5671949367-62581 1007346 D D

ATOM 12693 O GLUD231 57643 50031 63038 1007346 D ATOM 12768 CG2 THR D 241 4962443106 -73300 1006658

ATOM 12694 N ILE D 232 56463 48124-62975 1006793 D D

ATOM 12695 CA ILE D 232 5726747460-63989 1006793 D ATOM 12769 C THR D 241 50663 43368 -70501 1005948 D

ATOM 12696 CB ILE D 232 56733 46038-64282 1007426 D ATOM 12770 O THR D 241 4962943901-70101 1005948 D ATOM 12697 CG2 ILE D 232 57353 45479-65548 1004431 D ATOM 12771 N SER D 242 5120042309 -69902 1005744 D

ATOM 12698 CGl ILE D 232 5706645113-63120 1004431 D ATOM 12772 CA SER D 242 50555 41698 -68756 1005744 D

ATOM 12699 CDl ILE D 232 5654743690-63305 1004431 D ATOM 12773 CB SER D 242 4959440617 -69242 1008215 D

ATOM 12700 C ILE D 232 5729748243-65294 1006793 D ATOM 12774 OG SER D 242 5030839610 69945 1005467 D

ATOM 12701 O ILE D 232 58305 48230-65995 1006793 D ATOM 12775 C SER D 242 51515 41077-67755 1005744 D

ATOM 12702 N ASN D 233 56202 48925-65623 1007328 D ATOM 12776 O SER D 242 52712 40940 -68009 1005744 D

ATOM 12703 CA ASN D 233 56146 49683 -66866 1007328 D ATOM 12777 N LEU D 243 5094440679 -66624 1005494 D

ATOM 12704 CB ASN D 233 54703 49839-67334 1008328 D ATOM 12778 CA LEU D 243 51673 40051 -65540 1005494 D

ATOM 12705 CG ASN D 233 54120 48542 -67834 1007220 D ATOM 12779 CB LEU D 243 5186641066-64418 1006263 D

ATOM 12706 ODl ASN D 233 5483247708-68381 1007220 D ATOM 12780 CG LEU D 243 5283840674 -63310 1003876 D

ATOM 12707 ND2 ASN D 233 5281648368-67664 1007220 D ATOM 12781 CDl LEU D 243 54204 40409 -63912 1003876 D ATOM 12708 C ASN D 233 5681951052-66845 1007328 D ATOM 12782 CD2 LEU D 243 52909 41786 -62280 1003876 D

ATOM 12709 O ASN D 233 57003 51661-67903 1007328 D ATOM 12783 C LEU D 243 50855 38847 -65044 1005494 D

ATOM 12710 N LYS D 234 57191 51540-65663 10010706 D ATOM 12784 O LEU D 243 49627 38921 -64945 1005494 D

ATOM 12711 CA LYS D 234 57851 52839-65575 10010706 D ATOM 12785 N SER D 244 51533 37745 -64738 1004169 D

ATOM 12712 CB LYS D 234 57960 53287 64117 1007461 D ATOM 12786 CA SER D 244 50852 36547 -64265 1004169 D

ATOM 12713 CG LYS D 234 56621 53751-63573 1007461 D ATOM 12787 CB SER D 244 50833 35472 -65356 1004073 D

ATOM 12714 CD LYS D 234 56701 54253-62147 1007461 D ATOM 12788 OG SER D 244 5002035836 -66450 1004288 D

ATOM 12715 CE LYS D 234 55328 54738-61686 1007461 D ATOM 12789 C SER D 244 51473 35933 -63026 1004169 D 65251/C766

ATOM 127900 SER D 244 5269435900 -62 S91 1004169 D ATOM 12875 CG PHE D 256 55823 14720-53958 1003030 D ATOM 12791 N LEU D 245 50617 35447 -62128 1005567 D ATOM 12876 CDl PHE D 256 55900 15605 -52896 1003030 D

ATOM 12792 CA LEU D 245 5106434770 -60925 1005567 D ATOM 12877 CD2PHED256 56586 13558-53908 1003030 D

ATOM 12793 CB LEU D 245 50375 35340 -59694 1005698 D ATOM 12878 CEl PHE D 256 56709 15334 -51802 1003030 D

ATOM 12794 CG LEU D 245 50743 34586 -58416 1004097 D ATOM 12879 CE2PHED256 57399 13286-52816 1003030 D

ATOM 12795 CD1 LEUD245 5224434611-58217 1004097 D ATOM 12880 CZ PHE D 256 57455 14175-51766 1003030 D

ATOM 12796 CD2 LEU D 245 50029 35212-57228 1004097 D ATOM 12881 C PHE D 256 56285 16916-55878 1003983 D

ATOM 12797 C LEU D 245 50688 33295-61115 1005567 D ATOM 12882 O PHE D 256 57410 16881-55395 1003983 D

ATOM 12798 O LEU D 245 49512 32936-61098 1005567 D ATOM 12883 N GLY D 257 55608 18043-56054 1003969 D

ATOM 12799 N ILE D 246 51691 32450-61336 1003675 D ATOM 12884 CA GLY D 257 56185 19314-55665 1003969 D ATOM 12800 CA ILE D 246 51471 31024-61543 1003675 D ATOM 12885 C GLY D 257 55191 20438-55828 1003969 D

ATOM 12801 CB ILE D 246 52313 30504-62716 1004651 D ATOM 12886 O GLY D 257 5405620195-56217 1003969 D

ATOM 12802 CG2 ILE D 246 5199429051 -62986 1002955 D ATOM 12887 N SER D 258 5561021662 -55529 1003984 D

ATOM 12803 CGl ILE D 246 52023 31328 -63973 1002955 D ATOM 12888 CA SER D 258 5474022824 -55659 1003984 D

ATOM 12804 CDl ILE D 246 50579 31358 -64358 1002955 D ATOM 12889 CB SER D 258 54186 23233 -54299 1002876 D

ATOM 12805 C ILE D 246 51863 30255-60296 1003675 D ATOM 12890 OG SER D 258 55207 23767 -53469 1003888 D

ATOM 12806 O ILE D 246 53020 30283 -59884 1003675 D ATOM 12891 C SER D 258 55531 23981-56255 1003984 D

ATOM 12807 N THR D 247 50903 29573 59688 1003440 D ATOM 12892 O SER D 258 56755 23972 -56248 1003984 D

ATOM 12808 CA THR D 247 5119428812-58487 1003440 D ATOM 12893 N TYR D 259 5483824983-56768 1003852 D

ATOM 12809 CB THR D 247 50901 29643-57235 1005408 D ATOM 12894 CA TYR D 259 5552626108-57367 1003852 D

ATOM 12810 OGl THR D 247 5140028956 -56089 1005132 D ATOM 12895 CB TYR D 259 5577425834 -58854 1004469 D ATOM 12811 CG2THRD247 49423 29855-57063 1005132 D ATOM 12896 CG TYR D 259 5451725472-59587 1004044 D

ATOM 12812 C THR D 247 5036027534-58496 1003440 D ATOM 12897 CDl TYR D 259 53625 26457 60029 1004044

ATOM 12813 O THR D 247 49281 27497-59080 1003440 D D

ATOM 12814 N GLY D 248 50872 26478-57881 1004352 D ATOM 12898 CEl TYR D 259 5241026114-60606 1004044 D

ATOM 12815 CA GLY D 248 50145 25225-57867 1004352 D ATOM 12899 CD2 TYR D 259 54159 24138 -59756 1004044

ATOM 12816 C GLY D 248 5103724069-57472 1004352 D D

ATOM 12817 O GLYD248 52178 24275-57079 1004352 D ATOM 12900 CE2TYRD259 52951 23788 60332 1004044 D

ATOM 12818 N CYS D 249 5053022848-57574 1003977 D ATOM 12901 CZ TYR D 259 52081 24780-60748 1004044 D

ATOM 12819 CA CYS D 249 5132421691-57200 1003977 D ATOM 12902 OH TYR D 259 50865 24432 -61271 1004044 D

ATOM 12820 CB CYS D 249 51075 21336 -55735 1002913 D ATOM 12903 C TYR D 259 5474727402 -57209 1003852 D

ATOM 12821 SG CYS D 249 49491 20598-55443 1004790 D ATOM 12904 O TYR D 259 5355427397-56912 1003852 D ATOM 12822 C CYSD249 5101920490-58087 1003977 D ATOM 12905 N GLY D 260 5544728510-57418 1005363 D

ATOM 12823 O CYS D 249 5018620569-58987 1003977 D ATOM 12906 CA GLY D 260 54849 29820 -57306 1005363 D

ATOM 12824 N TYRD250 51696 19379-57835 1004422 D ATOM 12907 C GLY D 260 55822 30798-57918 1005363 D

ATOM 12825 CA TYR D 250 51492 18190-58644 1004422 D ATOM 12908 O GLY D 260 56855 31114-57335 1005363 D

ATOM 12826 CB TYR D 250 52291 18309-59932 1004551 D ATOM 12909 N TYR D 261 5551031265-59115 1004647 D

ATOM 12827 CG TYR D 250 53774 18393-59687 1003586 D ATOM 12910 CA TYR D 261 56380 32213-59783 1004647 D

ATOM 12828 CDl TYR D 250 54565 17236 -59623 1003586 D ATOM 12911 CB TYR D 261 57315 31480-60732 1005354 D

ATOM 12829 CEl TYR D 250 55937 17307 59344 1003586 D ATOM 12912 CG TYR D 261 56612 30717-61829 1003733 D

ATOM 12830 CD2 TYR D 250 54390 19627 -59469 I 003586 D ATOM 12913 CDl TYR D 261 56285 31331 -63036 1003733

ATOM 12831 CE2TYRD250 55761 19712-59187 1003586 D D

ATOM 12832 CZ TYR D 250 56529 18549-59125 1003586 D ATOM 12914 CEl TYR D 261 55696 30606 -64074 1003733 D

ATOM 12833 OH TYR D 250 57875 18637-58831 1003586 D ATOM 12915 CD2TYRD261 56322 29369 -61682 1003733

ATOM 12834 C TYRD250 51912 16913-57944 1004422 D D

ATOM 12835 O TYR D 250 52764 16924-57056 1004422 D ATOM 12916 CE2TYRD261 5573428641 -62705 1003733 D

ATOM 12836 N GLU D 251 51289 15820-58365 1005538 D ATOM 12917 CZ TYR D 261 5542629258 -63899 1003733 D

ATOM 12837 CA GLU D 251 51590 14489-57883 1005538 D ATOM 12918 OH TYR D 261 54872 28522 -64920 1003733 D

ATOM 12838 CB GLU D 251 50504 13986-56940 10010964 D ATOM 12919 C TYR D 261 5558633262 -60539 1004647 D

ATOM 12839 CG GLU D 251 50999 13833-55522 1006326 D ATOM 12920 O TYR D 261 5439733097 60795 1004647 D

ATOM 12840 CD GLU D 251 49999 13159-54604 1006326 D ATOM 12921 N VAL D 262 5626634344 -60890 1004558 D

ATOM 12841 OEl GLU D 251 49551 12032-54921 1006326 D ATOM 12922 CA VAL D 262 55658 35452-61607 1004558 D

ATOM 12842 OE2GLUD251 49668 13752-53552 1006326 D ATOM 12923 CB VAL D 262 55899 36781 -60864 1004073 D

ATOM 12843 C GLUD251 51619 13658-59162 1005538 D ATOM 12924 CGl VAL D 262 5549637943 -61742 1003222

ATOM 12844 O GLU D 251 50634 13023-59528 1005538 D D

ATOM 12845 N THR D 252 52750 13712-59859 1004709 D ATOM 12925 CG2 VAL D 262 55112 36807-59571 1003222

ATOM 12846 CA THRD252 52958 12997-61117 1004709 D D

ATOM 12847 CB THR D 252 53829 13838 -62072 1005929 D ATOM 12926 C VAL D 262 5627035566 -62986 I 004558 D

ATOM 12848 OGl THR D 252 53266 15154-62202 1005929 D ATOM 12927 O VAL D 262 5747735681 -63111 1004558 D

ATOM 12849 CG2THRD252 53917 13172-63438 1005929 D ATOM 12928 N GLU D 263 5544735508 -64023 1005200 D

ATOM 12850 C THR D 252 53689 11697-60807 1004709 D ATOM 12929 CA GLU D 263 55961 35649 -65374 1005200 D

ATOM 12851 O THR D 252 54918 11688 60691 1004709 D ATOM 12930 CB GLU D 263 55717 34391-66214 10011272

ATOM 12852 N GLY D 253 52943 10605-60675 1004404 D D

ATOM 12853 CA GLY D 253 53575 9344-60334 1004404 D ATOM 12931 CG GLU D 263 54294 33919 -66267 1009932 D

ATOM 12854 C GLY D 253 54254 9487-58974 1004404 D ATOM 12932 CD GLU D 263 54133 32685-67139 1009932 D

ATOM 12855 0 GLYD253 53644 9985-58014 1004404 D ATOM 12933 OEl GLU D 263 55004 31785-67071 1009932 ATOM 12856 N LEUD254 55512 9068-58878 1004601 D D

ATOM 12857 CA LEU D 254 56246 9184-57625 1004601 D ATOM 12934 OE2 GLU D 263 53129 32610-67884 1009932

ATOM 12858 CB LEU D 254 57512 8330-57640 1004040 D D

ATOM 12859 CG LEU D 254 57384 6813-57616 1004040 D ATOM 12935 C GLU D 263 5534236870 -66037 1005200 D

ATOM 12860 CDl LEU D 254 58760 6223-57432 1004040 D ATOM 12936 O GLU D 263 5431737404 -65602 1005200 D

ATOM 12861 CD2LEUD254 56474 6381-56502 1004040 D ATOM 12937 N THR D 264 5600237314 -67092 1005674 D

ATOM 12862 C LEU D 254 56662 10616-57331 1004601 D ATOM 12938 CA THR D 264 55599 38487 -67846 1005674 D

ATOM 12863 O LEUD254 56840 10983-56167 1004601 D ATOM 12939 CB THR D 264 56749 39514-67791 1007616 D

ATOM 12864 N LEU D 255 56837 11413-58383 1003932 D ATOM 12940 OGl THR D 264 5643440509 -66814 1005509

ATOM 12865 CA LEU D 255 57257 12803-58216 1003932 D D

ATOM 12866 CB LEU D 255 57746 13372-59551 1003089 D ATOM 12941 CG2 THR D 264 57010 40149-69127 1005509 ATOM 12867 CG LEU D 255 58815 12563-60299 1003089 D D

ATOM 1286S CDl LEU D 255 59230 13306 -61555 1003089 D ATOM 12942 C THR D 264 5529738075 -69276 1005674 D

ATOM 12869 CD2LEUD255 60016 12327-59413 1003089 D ATOM 12943 O THR D 264 5559936954 -69680 1005674 D

ATOM 12870 C LEU D 255 56153 13694-57650 1003932 D ATOM 12944 N ALA D 265 54683 38962 -70043 1006741 D

ATOM 12871 O LEU D 255 54969 13450-57868 1003932 D ATOM 12945 CA ALA D 265 54390 38631-71427 1006741 D

ATOM 12872 N PHE D 256 56552 14728-56918 1003983 D ATOM 12946 CB ALA D 265 53643 39768 -72090 1006770 D

ATOM 12873 CA PHED256 55593 15644-56318 1003983 D ATOM 12947 C ALA D 265 55711 38376-72143 1006741 D

ATOM 12874 CB PHE D 256 54907 14985-55115 1003329 D ATOM 12948 O ALA D 265 55742 37702-73171 1006741 D 65251/C766

ATOM 12949 N ASN D 266 5679638912-71582 1006538 D ATOM 13034 CA LYS D 277 6095433370 -48066 1006582 D ATOM 12950 CA ASN D 266 58135 38758-72146 1006538 D ATOM 13035 CB LYS D 277 60783 33633 -46572 1008396 D ATOM 12951 CB ASN D 266 5901639946 -71759 10012847 D ATOM 13036 CG LYS D 277 60346 32407 -45789 1006917 D ATOM 12952 CG ASN D 266 5840441273 -72145 1007032 D ATOM 13037 CD LYS D 277 60503 32635 -44296 1006917 D ATOM 12953 ODl ASN D 266 5799941475-73290 1007032 D ATOM 13038 CE LYS D 277 60010 31454-43467 1006917 D ATOM 12954 ND2 ASN D 266 5833942190-71191 1007032 D ATOM 13039 NZ LYS D 277 58519 31393-43395 1006917 D ATOM 12955 C ASN D 266 5881837466-71703 1006538 D ATOM 13040 C LYS D 277 61151 34686-48826 1006582 D ATOM 12956 O ASN D 266 59833 37066 -72279 1006538 D ATOM 13041 O LYS D 277 6101635776-48270 1006582 D ATOM 12957 N GLY D 267 5826436817-70682 1007310 D ATOM 13042 N ARG D 278 61470 34563 -50109 1004640 D ATOM 12958 CA GLY D 267 5883735576-70187 1007310 D ATOM 13043 CA ARG D 278 61693 35712-50975 1004640 D ATOM 12959 C GLY D 267 58973 35514-68673 1007310 D ATOM 13044 CB ARG D 278 63045 36340-50652 10010548 ATOM 12960 O GLY D 267 58727 36503 -67975 1007310 D D ATOM 12961 N PRO D 268 5938734357-68133 1005641 D ATOM 13045 CG ARG D 278 64204 35477 -51075 1009011 D ATOM 12962 CD PRO D 268 5997633229 -68870 1005329 D ATOM 13046 CD ARG D 278 6551035976-50513 1009011 D ATOM 12963 CA PRO D 268 59553 34174-66687 1005641 D ATOM 13047 NE ARG D 278 66642 35202 -51025 1009011 D ATOM 12964 CB PRO D 268 60277 32832 -66587 1006918 D ATOM 13048 CZ ARG D 278 67866 35225 -50502 1009011 D ATOM 12965 CG PRO D 268 6100432730-67887 1005329 D ATOM 13049 NHl ARG D 278 68121 35985-49442 1009011 ATOM 12966 C PRO D 268 60319 35309-66020 1005641 D D ATOM 12967 O PRO D 268 61335 35772-66524 1005641 D ATOM 13050 NH2 ARG D 278 68834 34493 -51042 1009011 ATOM 12968 N LEU D 269 5982635749 -64873 1006206 D D ATOM 12969 CA LEU D 269 60444 36847-64151 1006206 D ATOM 13051 C ARG D 278 61683 35233-52433 1004640 D ATOM 12970 CB LEU D 269 59383 37910-63874 1008793 D ATOM 13052 O ARG D 278 61691 34028-52706 1004640 D ATOM 12971 CG LEU D 269 59861 39298-63471 1005327 D ATOM 13053 N PHED279 61657 36168-53375 1004884 D ATOM 12972 CDl LEU D 269 6083639804 -64502 1005327 D ATOM 13054 CA PHE D 279 61672 35802-54790 1004884 D ATOM 12973 CD2 LEU D 269 58678 40241 -63357 1005327 D ATOM 13055 CB PHE D 279 60932 36833-55642 1006099 D ATOM 12974 C LEU D 269 6110036391 -62843 1006206 D ATOM 13056 CG PHE D 279 59449 36693-55610 1004476 D ATOM 12975 O LEU D 269 62328 36321 -62745 1006206 D ATOM 13057 CDl PHE D 279 58685 37391 -54676 1004476 D ATOM 12976 N ALA D 270 60287 36077 61837 1005473 D ATOM 13058 CD2 PHE D 279 58806 35864-56519 1004476 D ATOM 12977 CA ALA D 270 60806 35635 -60540 1005473 D ATOM 13059 CEl PHE D 279 5729637265 -54654 1004476 D ATOM 12978 CB ALA D 270 60819 36796-59566 1005620 D ATOM 13060 CE2 PHE D 279 5742435729 -56507 1004476 D ATOM 12979 C ALA D 270 6004734448 -59927 1005473 D ATOM 13061 CZ PHE D 279 5666636432-55573 1004476 D ATOM 12980 O ALA D 270 5883034314 -60064 1005473 D ATOM 13062 C PHE D 279 63105 35705-55293 1004884 D ATOM 12981 N ARG D 271 60798 33607 -59229 1006030 D ATOM 13063 0 PHE D 279 64006 36351 -54754 I 004884 D ATOM 12982 CA ARG D 271 60291 32400-58590 1006030 D ATOM 13064 N THR D 280 63303 34902 -56334 1004998 D ATOM 12983 CB ARG D 271 61160 31227-59043 1004416 D ATOM 13065 CA THR D 280 64615 34718-56923 1004998 D ATOM 12984 CG ARG D 271 60983 29966 -58294 1003728 D ATOM 13066 CB THR D 280 65215 33372-56543 1009139 D ATOM 12985 CD ARG D 271 6198028921-58793 1003728 D ATOM 13067 OGl THR D 280 65150 33212-55122 1007191 ATOM 12986 NE ARG D 271 61691 28448-60150 1003728 D D ATOM 12987 CZ ARG D 271 62389 28772-61232 1003728 D ATOM 13068 CG2 THR D280 66666 33298 -57004 1007191 ATOM 12988 NHl ARG D 271 6342929585-61136 1003728 D D ATOM 12989 NH2 ARG D 271 6205928262 -62405 1003728 D ATOM 13069 C THRD280 6451734760-58431 1004998 D ATOM 12990 C ARG D 271 60343 32569 -57078 1006030 D ATOM 13070 0 THRD280 63615 34177-59007 1004998 D ATOM 12991 O ARG D 271 61329 33053 -56533 1006030 D ATOM 13071 N LYS D 281 65458 35445-59067 1007017 D ATOM 12992 N TYR D 272 59279 32179-56394 1004235 D ATOM 13072 CA LYS D 281 65488 35562-60519 1007017 D ATOM 12993 CA TYR D 272 59238 32325 -54944 1004235 D ATOM 13073 CB LYS D 281 66806 36214-60944 10014355 D ATOM 12994 CB TYR D 272 57816 32607-54477 1004417 D ATOM 13074 CG LYS D 281 67992 35793-60081 10011949 D ATOM 12995 CG TYR D 272 57713 32795-52986 1004164 D ATOM 13075 CD LYS D 281 69185 35346-60916 10011949 D ATOM 12996 CDl TYR D 272 57985 34025-52410 1004164 D ATOM 13076 CE LYS D 281 69790 36481 -61734 10011949 D ATOM 12997 CEl TYR D 272 57906 34211 -51023 1004164 D ATOM 13077 NZ LYS D 281 71001 36044-62501 10011949 D ATOM 12998 CD2 TYR D 272 57358 31737 52144 1004164 D ATOM 13078 C LYSD281 65336 34210-61213 1007017 D ATOM 12999 CE2 TYR D 272 57278 31910-50761 1004164 D ATOM 13079 0 LYS D 281 65865 33203-60751 1007017 D ATOM 13000 CZ TYR D 272 57554 33152-50210 1004164 D ATOM 13080 N METD282 64596 34191 -62316 1005184 D ATOM 13001 OH TYR D 272 57482 33344 -48848 1004164 D ATOM 13081 CA METD 282 64414 32962-63081 1005184 D ATOM 13002 C TYR D 272 5974431078-54233 004235 D ATOM 13082 CB METD 282 62950 32764-63468 1006683 D ATOM 13003 O TYR D 272 5920629987 -54422 004235 D ATOM 13083 CG METD 282 62031 32400-62326 1006683 D ATOM 13004 N HIS D 273 60764 31239-53397 1006273 D ATOM 13084 SD MET D 282 60468 31741-62943 1006683 D ATOM 13005 CA HIS D 273 61319 30108-52664 1006273 D ATOM 13085 CE MET D 282 59509 33228 63105 1006683 D ATOM 13006 CB HIS D 273 62844 30148 -52690 10012243 D ATOM 13086 C METD282 65242 33060-64353 1005184 D ATOM 13007 CG HIS D 273 6341929753-54010 10010316 D ATOM 13087 O MET D 282 6538232093 -65094 1005184 D ATOM 13008 CD2 HIS D 273 6419030433 -54890 10010316 D ATOM 13088 N THR D 283 6578034251-64598 1009108 D ATOM 13009 NDl HIS D 273 6317928522 -54580 10010316 D ATOM 13089 CA THR D 283 66593 34524-65776 1009108 D ATOM 13010 CEl HIS D 273 63777 28460 -55757 10010316 D ATOM 13090 CB THR D 283 65801 35359-66793 1007384 D ATOM 13011 NE2 HIS D 273 64398 29607 -55969 10010316 D ATOM 13091 OGl THR D 283 64688 34596-67262 1007384 ATOM 13012 C HIS D 273 60825 30026 -51236 1006273 D D ATOM 13013 O HIS D 273 61013 30936-50432 1006273 D ATOM 13092 CG2 THR D 283 66668 35741 -67970 1007384 ATOM 13014 N THR D 274 60173 28912-50944 1005888 D D ATOM 13015 CA THR D 274 59625 28633 -49629 1005888 D ATOM 13093 C THRD283 67820 35317-65351 1009108 D ATOM 13016 CB THR D 274 58975 27240 -49625 1006778 D ATOM 130940 THR D 283 6781835942-64290 1009108 D ATOM 13017 OGl THR D 274 57567 27386 -49830 1006031 D ATOM 13095 N HISD284 68865 35281 -66174 1009517 D ATOM 13018 CG2 THR D 274 5924726504-48325 1006031 D ATOM 13096 CA HIS D 284 70093 36024 -65899 1009517 D ATOM 13019 C THR D 274 6068228714 -48536 1005888 D ATOM 13097 CB HIS D 284 71093 35825-67043 10013709 D ATOM 13020 O THR D 274 6040429176-47434 1005888 D ATOM 13098 CG HIS D 284 7055236205-68390 10013709 D ATOM 13021 N GLY D 275 61893 28260 -48849 1006283 D ATOM 13099 CD2HISD284 70915 37182 69255 10013709 D ATOM 13022 CA GLY D 275 62977 28292 -47881 1006283 D ATOM 13100 NDl HIS D 284 69485 35555-68975 10013709 D ATOM 13023 C GLY D 275 63431 29695-47513 1006283 D ATOM 13101 CEl HIS D 284 69215 36115-70141 10013709 D ATOM 13024 O GLY D 275 63301 30110-46366 1006283 D ATOM 13102 NE2 HIS D 284 70068 37105 70335 10013709 D ATOM 13025 N ASP D 276 63952 30428 -48490 1006255 D ATOM 13103 C HISD284 69743 37509-65784 1009517 D ATOM 13026 CA ASP D 276 64431 31789-48276 1006255 D ATOM 13104 O HISD284 70319 38239-64973 1009517 D ATOM 13027 CB ASP D 276 65203 32251 -49504 10015537 D ATOM 13105 N LYSD285 68782 37929-66607 1008136 D ATOM 13028 CG ASP D 276 66218 31236-49957 10013437 D ATOM 13106 CA LYS D 285 6830039304 -66674 1008136 D ATOM 13029 ODl ASP D 276 6720931026-49227 10013437 D ATOM 13107 CB LYS D285 67075 39368-67587 1009823 D ATOM 13030 OD2 ASP D 276 66017 30640-51037 10013437 D ATOM 13108 CG LYS D 285 6714940434-68663 1009823 D ATOM 13031 C ASP D 276 63332 32813 -47976 1006255 D ATOM 13109 CD LYS D 285 6826440139-69661 1009823 D ATOM 13032 O ASP D 276 63621 33904-47478 1006255 D ATOM 13110 CE LYS D 285 6832241196-70759 1009823 D ATOM 13033 N LYS D 277 62082 32469 -48287 1006582 D ATOM 13111 NZ LYS D 285 6939640917-71749 1009823 D 65251/C766

ATOM 13112 C LYS D 285 67944 39925 -65322 1008136 D ATOM 13197 CB ASN D 297 55 714 45 590 -51 134 1 00 65 43

ATOM 13113 O LYS D 285 68082 41133-65139 1008136 D ATOM 13198 CG ASN D 297 54285 45 968 -51 488 1 00 65 43

ATOM 13114 N GLY D 286 67486 39103-64381 1005905 D ATOM 13199 ODl ASN D 297 53 382 45 912 -50 647 1 00 65 43

ATOM 13115 CA GLY D 286 6710439609 -63072 1005905 D D

ATOM 13116 C GLY D 286 6566640094 -63109 1005905 D ATOM 13200 ND2 ASN D 297 54 073 46 358 -52 741 1 0065 43

ATOM 13117 O GLY D 286 64997 39954 -64133 1005905 D D

ATOM 13118 N PHE D 287 6517840656-62006 1006103 D ATOM 13201 C ASN D 297 55 547 46295 -48743 1 0053 99 D

ATOM 13119 CA PHE D 287 63805 41160 61959 1006103 D ATOM 13202 O ASN D 297 55 765 45 338 -48001 1 0053 99 D

ATOM 13120 CB PHE D 287 6286440097 -61389 1004722 D ATOM 13203 N THR D 298 54 641 47 226 -48 478 1 0049 34 D

ATOM 13121 CG PHE D 287 6308439808 -59929 1004722 D ATOM 13204 CA THR D 298 53 825 47 199 -47286 1 00 49 34 D

ATOM 13122 CDl PHE D 287 6246040574 -58952 1004722 D ATOM 13205 CB THR D 298 52 934 48 453 -47244 1 00 76 17 D

ATOM 13123 CD2 PHE D 287 63905 38756 -59528 1004722 D ATOM 13206 OGl THR D 298 51 846 48 232 -46346 1 00 76 17

ATOM 13124 CE 1 PHE D 287 6264840297 -57595 1004722 D D

ATOM 13125 CE2 PHE D 287 64101 38467-58165 1004722 D ATOM 13207 CG2 THR D 298 52 391 48 779 -48 627 1 0076 17

ATOM 13126 CZ PHE D 287 63473 39237 -57202 1004722 D D

ATOM 13127 C PHE D 287 63721 42424-61117 1006103 D ATOM 13208 C THR D 298 52 955 45 937 -47 168 1 0049 34 D

ATOM 13128 O PHE D 287 6438042543 60081 1006103 D ATOM 13209 0 THR D 298 52 584 45 541 -46 065 1 0049 34 D

ATOM 13129 N PRO D 288 6289443388 -61546 1006774 D ATOM 13210 N LEU D 299 52 636 45 300 -48291 1 00 56 01 D

ATOM 13130 CD PRO D 288 6199443315-62711 1006129 D ATOM 13211 CA LEU D 299 51 802 44 104 -48 260 1 00 5601 D

ATOM 13131 CA PRO D 288 62722 44656 -60831 1006774 D ATOM 13212 CB LEU D 299 50 790 44 154 -49 394 1 00 52 60 D

ATOM 13132 CB PRO D 288 6183745462-61775 1006129 D ATOM 13213 CG LEU D 299 49 759 45 269 -49 269 1 00 52 60 D

ATOM 13133 CG PRO D 288 6098644404 -62408 1006129 D ATOM 13214 CDl LEU D 299 48 915 45 294 -50527 1 00 52 60 D

ATOM 13134 C PRO D 288 6209744480 59458 1006774 D ATOM 13215 CD2 LEU D 299 48 905 45 048 -48 029 1 00 52 60 D

ATOM 13135 O PRO D 288 6101343906 59332 1006774 D ATOM 13216 C LEU D 299 52 583 42798 -48336 1 005601 D

ATOM 13136 N LYS D 289 6278444968 -58430 1005947 D ATOM 13217 0 LEU D 299 51 995 41 715 -48439 1 00 56 01 D

ATOM 13137 CA LYS D 289 62268 44863 -57074 1005947 D ATOM 13218 N TRP D 300 53 907 42 899 -48 281 1 00 54 84 D

ATOM 13138 CB LYS D 289 6341444914 56061 10012523 D ATOM 13219 CA TRP D 300 54 760 41 721 -48 345 1 0054 84 D

ATOM 13139 CG LYS D 289 64179 43598-55979 10012523 D ATOM 13220 CB TRP D 300 56 196 42 089 -48009 1 00 5692 D

ATOM 13140 CD LYS D 289 6532443667 -54991 10012523 D ATOM 13221 CG TRP D 300 57 127 40 933 -48 105 1 00 56 92 D

ATOM 13141 CE LYS D 289 66445 44562-55511 10012523 D ATOM 13222 CD2 TRP D 300 57403 40 143 ^19 272 1 005692 D

ATOM 13142 NZ LYS D 289 67607 44618-54578 10012523 D ATOM 13223 CE2 TRP D 300 58356 39 170 -48 903 1 00 5692 D

ATOM 13143 C LYS D 289 6121645941 56794 1005947 D ATOM 13224 CE3 TRP D 300 56938 40 166 -50 592 1 00 56 92 D

ATOM 13144 O LYS D 289 6147446951 -56141 1005947 D ATOM 13225 CDl TRP D 300 57 897 40 420 -47 106 1 00 56 92 D

ATOM 13145 N VAL D 290 6001245687 -57300 1007187 D ATOM 13226 NEl TRP D 300 58 641 39 359 -47 577 1 00 56 92 D

ATOM 13146 CA VAL D 290 58883 46589-57145 1007187 D ATOM 13227 CZ2 TRP D 300 58 853 38 229 -49 804 1 00 5692 D

ATOM 13147 CB VAL D 290 58647 47380 -58444 1006385 D ATOM 13228 CZ3 TRP D 300 57434 39 231 -51 490 1 00 5692 D

ATOM 13148 CGl VAL D 290 5993448042 -58885 1006385 D ATOM 13229 CH2 TRP D 300 58 382 38 275 -51 092 1 00 56 92 D

ATOM 13149 CG2 VAL D 290 58132 46446-59537 1006385 D ATOM 13230 C TRP D 300 54 307 40 614 -47 408 1 00 54 84 D

ATOM 13150 C VAL D 290 5762045788 -56836 1007187 D ATOM 13231 O TRP D 300 54 308 39 445 -47 790 1 00 54 84 D

ATOM 13151 O VAL D 290 5760044569 -56967 1007187 D ATOM 13232 N LYS D 301 53 924 40975 -46 186 1 00 54 12 D

ATOM 13152 N GLY D 291 56571 46490-56430 1005744 D ATOM 13233 CA LYS D 301 53 478 39 982 -45 216 1 0054 12 D

ATOM 13153 CA GLY D 291 55303 45846 -56134 1005744 D ATOM 13234 CB LYS D 301 53 066 40 646 -43 897 1 00 81 50 D

ATOM 13154 C GLY D 291 5537244642 -55222 1005744 D ATOM 13235 CG LYS D 301 54 187 41 442 -43 232 1 00 81 50 D

ATOM 13155 O GLY D 291 56021 44676-54180 1005744 D ATOM 13236 CD LYS D 301 55 495 40 631 -43 155 1 00 81 50 D

ATOM 13156 N MET D 292 54688 43577 -55623 1006459 D ATOM 13237 CE LYS D 301 56 714 41 520 -42 887 1 00 81 50 D

ATOM 13157 CA MET D 292 5464842335 54860 1006459 D ATOM 13238 NZ LYS D 301 57 999 40 832 -43 205 1 00 81 50 D

ATOM 13158 CB MET D 292 5359441410-55451 1007671 D ATOM 13239 C LYS D 301 52324 39 158 -45 765 1 0054 12 D

ATOM 13159 CG MET D 292 54003 40900-56814 1007671 D ATOM 13240 0 LYS D 301 52 247 37 954 -45 510 1 00 54 12 D

ATOM 13160 SD MET D 292 53097 39456-57324 1007671 D ATOM 13241 N ASP D 302 51 431 39 791 -46 528 1 00 55 09 D

ATOM 13161 CE MET D 292 52225 40098 -58733 1007671 D ATOM 13242 CA ASP D 302 50 307 39 064 -47096 1 0055 09 D

ATOM 13162 C MET D 292 5598941590 -54880 1006459 D ATOM 13243 CB ASP D 302 49 242 40028 -47 609 1 00 84 07 D

ATOM 13163 O MET D 292 56121 40530-54279 1006459 D ATOM 13244 CG ASP D 302 48 500 40 707 -46487 1 00 84 07 D

ATOM 13164 N LEU D 293 5698042136-55571 1005628 D ATOM 13245 ODl ASP D 302 48035 39 991 -45 578 1 00 8407 D

ATOM 13165 CA LEU D 293 58265 41472 -55673 1005628 D ATOM 13246 OD2 ASP D 302 48 378 41 948 -46 510 1 00 8407 D

ATOM 13166 CB LEU D 293 58817 41642-57088 1005205 D ATOM 13247 C ASP D 302 50 788 38 159 -48 211 1 0055 09 D

ATOM 13167 CG LEU D 293 57996 40964 -58185 1005205 D ATOM 13248 O ASP D 302 50295 37 041 -48 356 1 00 55 09 D

ATOM 13168 CDl LEU D 293 58552 41299 -59563 1005205 D ATOM 13249 N VAL D 303 51 753 38 636 -48 994 1 00 44 08 D

ATOM 13169 CD2 LEU D 293 58021 39472-57958 1005205 D ATOM 13250 CA VAL D 303 52 296 37 831 -50 076 1 004408 D

ATOM 13170 C LEU D 293 5934841857 -54664 1005628 D ATOM 13251 CB VAL D 303 53 414 38 568 -50 819 1 0048 62 D

ATOM 13171 O LEU D 293 6042741264 -54679 1005628 D ATOM 13252 CGl VAL D 303 54049 37 654 -51 856 1 00 37 93

ATOM 13172 N THR D 294 5908942833 -53796 1006661 D D

ATOM 13173 CA THR D 294 60097 43222 -52807 1006661 D ATOM 13253 CG2 VAL D 303 52 849 39 788 -51 491 1 00 37 93

ATOM 13174 CB THR D 294 60617 44645 -53007 1008683 D D

ATOM 13175 OGl THR D 294 6076244916-54401 1008683 D ATOM 13254 C VAL D 303 52 855 36543 -49483 1 004408 D

ATOM 13176 CG2 THR D 294 6197644796-52319 1008683 D ATOM 13255 O VAL D 303 52 486 35445 -49 918 1 0044 08 D

ATOM 13177 C THR D 294 5958343180-51390 1006661 D ATOM 13256 N LYS D 304 53 734 36 678 -48 486 1 0061 07 D

ATOM 13178 O THR D 294 5840243385-51139 1006661 D ATOM 13257 CA LYS D 304 54 332 35 520 -47 820 1 00 61 07 D

ATOM 13179 N VAL D 295 60491 42939 50458 1006977 D ATOM 13258 CB LYS D 304 55 112 35 949 -46 581 1 00 77 60 D

ATOM 13180 CA VAL D 295 60121 42894-49060 1006977 D ATOM 13259 CG LYS D 304 56 514 36432 -46 826 1 0059 52 D

ATOM 13181 CB VAL D 295 61288 42374-48215 1005945 D ATOM 13260 CD LYS D 304 57 135 36869 -45504 1 0059 52 D

ATOM 13182 CGl VAL D 295 60868 42263 -46743 1005945 D ATOM 13261 CE LYS D 304 58 595 37257 -45 673 1 00 59 52 D

ATOM 13183 CG2 VAL D 295 6174441030 -48761 1005945 D ATOM 13262 NZ LYS D 304 59 171 37 808 -44418 1 00 59 52 D

ATOM 13184 C VAL D 295 5977044315 -48636 1006977 D ATOM 13263 C LYS D 304 53 252 34 536 -47 382 I 00 61 07 D

ATOM 13185 O VAL D 295 5907844534 -47636 1006977 D ATOM 13264 O LYS D 304 53 359 33 330 -47 599 1 00 61 07 D

ATOM 13186 N LYS D 296 60245 45277-49421 1006398 D ATOM 13265 N ALA D 305 52 202 35 062 -46 772 1 004925 D

ATOM 13187 CA LYS D 296 6000646690-49152 1006398 D ATOM 13266 CA ALA D 305 51 131 34 229 -46277 1 0049 25 D

ATOM 13188 CB LYS D 296 60683 47552 -50222 1009600 D ATOM 13267 CB ALA D 305 50 259 35 037 -45 365 1 002725 D

ATOM 13189 CG LYS D 296 6219747390-50317 1009600 D ATOM 13268 C ALA D 305 50282 33 572 -47 352 1 004925 D

ATOM 13190 CD LYS D 296 62921 48057-49155 1009600 D ATOM 13269 O ALA D 305 50056 32 361 -47 315 1 00 4925 D

ATOM 13191 CE LYS D 296 6280249574 -49229 1009600 D ATOM 13270 N TYR D 306 49 798 34 357 -48 308 1 004934 D

ATOM 13192 NZ LYS D 296 6347650260 -48092 1009600 D ATOM 13271 CA TYR D 306 48 953 33 806 -49358 1 0049 34 D

ATOM 13193 C LYS D 296 58515 47006^9128 1006398 D ATOM 13272 CB TYR D 306 48 239 34932 -50 102 1 00 55 36 D

ATOM 13194 O LYS D 296 58071 47883-48373 1006398 D ATOM 13273 CG TYR D 306 47 239 35 670 -49 256 1 00 50 05 D

ATOM 13195 N ASN D 297 5774946284-49951 1005399 D ATOM 13274 CDl TYR D 306 46950 37 016 ^(9 491 1 00 5005

ATOM 13196 CA ASN D 297 56309 46493 -50053 1005399 D D 65251/C766

ATOM 13275 CEl TYR D 306 46025 37701-48719 1005005 D ATOM 13360 C LEU D 317 45269 19641 -49904 1004270 D ATOM 13276 CD2 TYR D 306 46574 35026 -48227 1005005 D ATOM 13361 O LEU D 317 44447 18713-50002 1004270 D

ATOM 13277 CE2 TYR D 306 45645 35698 -47450 1005005 D ATOM 13362 N ALA D 318 4511220807-50522 1003561 D

ATOM 13278 CZ TYR D 306 45376 37034 -47699 1005005 D ATOM 13363 CA ALA D 318 43923 21081 -51309 1003561 D

ATOM 13279 OH TYR D 306 44457 37684^16910 1005005 D ATOM 13364 CB ALAD318 43952 22520 -51812 1003104 D

ATOM 13280 C TYR D 306 4970232939-50346 1004934 D ATOM 13365 C ALAD318 4375720126 -52474 1003561 D

ATOM 13281 O TYRD306 4929031 S19 -50616 1004934 D ATOM 13366 O ALA D 318 42685 19565-52690 1003561 D

ATOM 13282 N LEU D 307 50798 33455 -50889 1004663 D ATOM 13367 N ILED319 44824 19937-53229 1003902 D

ATOM 13283 CA LEU D 307 5157732711 -51872 1004663 D ATOM 13368 CA ILE D 319 44751 19062-54392 1003902 D

ATOM 13284 CB LEU D 307 5239433662 -52738 1005999 D ATOM 13369 CB ILE D 319 46146 18779-54981 1005598 D ATOM 13285 CG LEU D 307 53392 33002 53694 1002812 D ATOM 13370 CG2ILED319 46923 17843-54079 1003054 D

ATOM 13286 CDl LEU D 307 52681 32097-54684 1002812 D ATOM 13371 CGl ILE D 319 45987 18162-56368 1003054 D

ATOM 13287 CD2 LEU D 307 54165 34100-54423 1002812 D ATOM 13372 CDl ILE D 319 47298 17978-57131 1003054 D

ATOM 13288 C LEU D 307 52505 31707-51218 1004663 D ATOM 13373 C ILE D 319 44065 17734-54083 1003902 D

ATOM 13289 O LEU D 307 5251530532-51587 1004663 D ATOM 13374 O ILED319 43418 17171-54949 1003902 D

ATOM 13290 N GLY D 308 53291 32172-50253 1004270 D ATOM 13375 N LEU D 320 44193 17246 52849 1003980 D

ATOM 13291 CA GLY D 308 54199 31282-49567 1004270 D ATOM 13376 CA LEU D 320 43564 15980 -52480 1003980 D

ATOM 13292 C GLY D 308 5345830138-48893 1004270 D ATOM 13377 CB LEU D 320 44147 15461 -51156 1006649 D

ATOM 13293 O GLY D 308 53845 28976-49030 1004270 D ATOM 13378 CG LEU D 320 45637 15076-51210 1004433 D

ATOM 13294 N GLY D 309 52387 30453-48171 1004318 D ATOM 13379 CDl LEU D 320 46089 14564-49858 1004433 D

ATOM 13295 CA GLYD309 51643 29416-47477 1004318 D ATOM 13380 CD2 LEU D 320 45880 14019-52291 1004433 D ATOM 13296 C GLY D 309 5109228339-48389 1004318 D ATOM 13381 C LEU D 320 42036 16085 -52395 1003980 D

ATOM 13297 O GLYD309 51245 27137-48141 1004318 D ATOM 13382 O LEU D 320 41326 15118-52686 1003980 D

ATOM 13298 N PHE D 310 50445 28779-49461 1004187 D ATOM 13383 N ASP D 321 41533 17260-52012 1004617 D

ATOM 13299 CA PHE D 310 4984927871 -50424 1004187 D ATOM 13384 CA ASP D 321 40092 17462-51922 1004617 D

ATOM 13300 CB PHE D 310 49214 28675-51553 1003933 D ATOM 13385 CB ASP D 321 39765 18766-51183 1009454 D

ATOM 13301 CG PHED310 48351 27859-52466 1003516 D ATOM 13386 CG ASP D 321 40051 18687-49690 1007354 D

ATOM 13302 CD1 PHED310 47215 27212 51980 1003516 D ATOM 13387 ODl ASP D 321 39697 17658-49075 1007354 D

ATOM 13303 CD2PHED310 48656 27762 53816 1003516 D ATOM 13388 OD2 ASP D 321 40612 19667-49135 1007354 D

ATOM 13304 CEl PHED310 4638826477-52827 1003516 D ATOM 13389 C ASP D 321 39507 17502-53335 1004617 D

ATOM 13305 CE2PHED310 4783927031 -54680 1003516 D ATOM 13390 O ASP D 321 38421 16982-53585 1004617 D

ATOM 13306 CZ PHE D 310 46699 26386-54180 1003516 D ATOM 13391 N TYR D 322 40236 18115 -54264 1004907 D

ATOM 13307 C PHE D 310 5090926944-50996 1004187 D ATOM 13392 CA TYR D 322 39777 18202 -55645 1004907 D

ATOM 13308 O PHE D 310 5069425736-51125 1004187 D ATOM 13393 CB TYR D 322 40770 18977-56517 1004394 D

ATOM 13309 N GLUD311 5205027534-51341 1003359 D ATOM 13394 CG TYR D 322 40745 20483 56344 1003465 D

ATOM 13310 CA GLU D 311 53161 26800-51917 1003359 D ATOM 13395 CDl TYR D 322 4122021080-55177 1003465

ATOM 13311 CB GLUD311 54194 27767-52490 1009321 D D

ATOM 13312 CG GLU D 311 55049 27143-53571 1007744 D ATOM 13396 CEl TYR D 322 4122722472 -55028 1003465 D

ATOM 13313 CD GLU D 311 56186 28036 -54020 1007744 D ATOM 13397 CD2 TYR D 322 40271 21315-57361 1003465

ATOM 13314 OEl GLUD311 5598729265-54126 1007744 D D

ATOM 13315 OE2GLUD311 57282 27500-54286 1007744 D ATOM 13398 CE2TYRD322 4027822711 -57223 1003465 D

ATOM 13316 C GLUD311 53825 25897-50889 1003359 D ATOM 13399 CZ TYR D 322 40761 23281-56054 1003465 D

ATOM 13317 0 GLUD311 5429024805-51213 1003359 D ATOM 13400 OH TYR D 322 40818 24647-55919 1003465 D

ATOM 13318 N TYR D 312 53853 26339-49642 1004087 D ATOM 13401 C TYR D 322 39648 16796-56187 1004907 D

ATOM 13319 CA TYR D 312 5448925555-48600 1004087 D ATOM 13402 O TYR D 322 38626 16419-56770 1004907 D

ATOM 13320 CB TYR D 312 54687 26380-47339 1005724 D ATOM 13403 N GLN D 323 40701 16016-55986 1004742 D

ATOM 13321 CG TYR D 312 5542025624-46265 1005194 D ATOM 13404 CA GLN D 323 40726 14650-56456 1004742 D

ATOM 13322 CDl TYR D 312 5678025374-46374 1005194 D ATOM 13405 CB GLN D 323 41980 13954-55964 1007741 D

ATOM 13323 CEl TYR D 312 57460 24640-45394 1005194 D ATOM 13406 CG GLN D 323 42067 12536-56424 1005180 D

ATOM 13324 CD2 TYR D 312 54744 25124 -45147 1005194 D ATOM 13407 CD GLN D 323 43369 11889-56036 1005180 D

ATOM 13325 CE2TYRD312 55409 24388-44158 1005194 D ATOM 13408 OEl GLN D 323 43784 11933-54870 1005180

ATOM 13326 CZ TYR D 312 56764 24151-44289 1005194 D D

ATOM 13327 OH TYR D 312 57423 23423-43320 1005194 D ATOM 13409 NE2 GLN D 323

ATOM 13328 C TYR D 312 5372624305-48236 1004087 D D

ATOM 13329 O TYRD312 5432523276-47958 1004087 D ATOM 13410 C GLN D 323 39485 13892-56000 1004742 D

ATOM 13330 N MET D 313 5240824376-48222 1004369 D ATOM 13411 O GLN D 323 38850 13230-56807 1004742 D

ATOM 13331 CA METD313 51645 23192-47870 1004369 D ATOM 13412 N LYS D 324 39136 13994-54718 1003854 D

ATOM 13332 CB MET D 313 51727 22966 -46364 1005591 D ATOM 13413 CA LYS D 324 37952 13310-54187 1003854 D

ATOM 13333 CG METD313 5100721729-45897 1005576 D ATOM 13414 CB LYS D 324 37734 13648-52710 1008192 D

ATOM 13334 SD MET D 313 50996 21629^M 128 1005576 D ATOM 13415 CG LYS D 324 38628 12928-51747 1007135 D

ATOM 13335 CE MET D 313 52770 21629-43812 1005576 D ATOM 13416 CD LYS D 324 38133 13121 -50328 1007135 D

ATOM 13336 C MET D 313 5017723241 ^t8295 1004369 D ATOM 13417 CE LYS D 324 39001 12369 -49328 1007135 D

ATOM 13337 O MET D 313 49585 22210-48646 1004369 D ATOM 13418 NZ LYS D 324 38464 12437 47928 1007135 D

ATOM 13338 N GLYD314 4959724438-48257 1003320 D ATOM 13419 C LYS D 324 36682 13691-54950 1003854 D

ATOM 13339 CA GLY D 314 48203 24599-48619 1003320 D ATOM 13420 O LYS D 324 35920 12826-55391 1003854 D

ATOM 13340 C GLY D 314 4777523852-49866 1003320 D ATOM 13421 N MET D 325 36447 14989-55097 1005231 D ATOM 13341 O GLY D 314 4682223058-49845 1003320 D ATOM 13422 CA MET D 325 35247 15443-55768 1005231 D

ATOM 13342 N CYS D 315 4848524100-50959 1004589 D ATOM 13423 CB MET D 325 34989 16904-55451 1006627 D

ATOM 13343 CA CYSD315 48164 23457 52217 1004589 D ATOM 13424 CG MET D 325 34677 17134-54016 1005483 D

ATOM 13344 CB CYSD315 4912823929-53295 1006449 D ATOM 13425 SD MET D 325 34384 18838-53701 1005483 D

ATOM 13345 SG CYS D 315 48592 23501-54946 1006986 D ATOM 13426 CE MET D 325 36015 19361-53064 1005483 D

ATOM 13346 C CYSD315 4818321934-52142 1004589 D ATOM 13427 C MET D 325 35290 15253-57268 1005231 D

ATOM 13347 0 CYSD315 4720821280-52513 1004589 D ATOM 13428 O MET D 325 34265 15356 57941 1005231 D

ATOM 13348 N SERD316 4928621364-51661 1004857 D ATOM 13429 N ALA D 326 36464 14964-57808 1003889 D

ATOM 13349 CA SER D 316 49393 19910-51565 1004857 D ATOM 13430 CA ALA D 326 36550 14791-59246 1003889 D

ATOM 13350 CB SER D 316 50703 19513-50915 1003646 D ATOM 13431 CB ALA D 326 37872 15369-59767 1002618 D

ATOM 13351 OG SER D 316 50705 19888 -49553 1004196 D ATOM 13432 C ALA D 326 36424 13336-59657 1003889 D ATOM 13352 C SERD316 48250 19284-50779 1004857 D ATOM 13433 O ALA D 326 36024 13048-60785 1003889 D

ATOM 13353 O SER D 316 47913 18132-50999 1004857 D ATOM 13434 N LYS D 327 36756 12435-58733 1009915 D

ATOM 13354 N LEU D 317 4766620027 -49848 1004270 D ATOM 13435 CA LYS D 327 36748 10999-58982 1009915 D

ATOM 13355 CA LEUD317 46552 19496-49078 1004270 D ATOM 13436 CB LYS D 327 36338 10220-57735 10015788 D

ATOM 13356 CB LEU D 317 4640620253-47751 1004181 D ATOM 13437 CG LYS D 327 36619 8728-57879 1007617 D

ATOM 13357 CG LEU D 317 47478 19994-46687 1003432 D ATOM 13438 CD LYS D 327 36343 7965-56595 1007617 D

ATOM 13358 CDl LEU D 317 4730720919-45507 1003432 D ATOM 13439 CE LYS D 327 36741 6497-56721 1007617 D

ATOM 13359 CD2LEUD317 47382 18556-46243 1003432 D ATOM 13440 NZ LYS D 327 36447 5726-55475 1007617 D 65251/C766

ATOM 13441 C LYS D 327 35900 10535-60147 1009915 D ATOM 13526 CG LYS D 339 57251 2040-78227 1009911 D ATOM 13442 O LYSD327 36426 10052-61152 1009915 D ATOM 13527 CD LYS D 339 56172 2362-79253 1009911 D

ATOM 13443 N GLY D 328 34590 10682-60037 10039 S3 D ATOM 13528 CE LYS D 339 54989 1403 79119 1009911 D

ATOM 13444 CA GLY D 328 33760 10216-61133 1003983 D ATOM 13529 NZ LYS D 339 53824 1807-79952 1009911 D

ATOM 13445 C GLY D 328 33465 11164-62290 1003983 D ATOM 13530 C LYS D 339 60105 4301-76890 1007515 D

ATOM 13446 O GLY D 328 33174 10718-63397 1003983 D ATOM 13531 O LYS D 339 59857 5501 -77018 1006781 D

ATOM 13447 N LYS D 329 33556 12472-62065 1004704 D ATOM 13532 N VALD 340 61340 3830-76772 1006834 D

ATOM 13448 CA LYSD329 33221 13421 -63118 1004704 D ATOM 13533 CA VAL D 340 62495 4720-76855 1006577 D

ATOM 13449 CB LYS D 329 32553 14639-62478 10017674 D ATOM 13534 CB VAL D 340 63489 4474-75708 1005049 D

ATOM 13450 CG LYS D 329 31225 14315-61814 10017674 D ATOM 13535 CGl VAL D 340 64666 5421 -75831 1003595 D ATOM 13451 CD LYS D 329 30414 15573-61615 10017674 D ATOM 13536 CG2 VALD 340 62811 4674-74389 1003595 D

ATOM 13452 CE LYS D 329 29047 15290-61029 1006650 D ATOM 13537 C VALD340 63210 4425-78167 1006834 D

ATOM 13453 NZ LYS D 329 28279 16575-60918 1006650 D ATOM 13538 0 VAL D 340 63579 3292-78409 1006519 D

ATOM 13454 C LYS D 329 34250 13884-64158 1004704 D ATOM 13539 N THR D 341 63408 5433-79008 1007335 D

ATOM 13455 O LYSD329 34014 14863 64852 1004704 D ATOM 13540 CA THR D 341 64075 5216-80287 1006925 D

ATOM 13456 N ILE D 330 35378 13199-64301 1003669 D ATOM 13541 CB THR D 341 63226 5752-81451 10012799 D

ATOM 13457 CA ILED330 36371 13620-65310 1003669 D ATOM 13542 OGl THR D 341 61968 5074-81469 10010935

ATOM 13458 CB ILE D 330 37539 14457-64685 1003398 D D

ATOM 13459 CG2ILED33O 36980 15668-63917 1003490 D ATOM 13543 CG2 THR D 341 63931 5523 82779 10010935

ATOM 13460 CG1 ILED33O 38388 13584-63762 1003490 D D

ATOM 13461 CDl ILE D 330 39702 14209-63431 1003490 D ATOM 13544 C THR D 341 65443 5880-80342 1007140 D ATOM 13462 C ILE D 330 36960 12399-66024 1003669 D ATOM 13545 O THR D 341 65656 6961 79782 1007300 D

ATOM 13463 O ILE D 330 36723 11265-65604 1003669 D ATOM 13546 N GLYD342 66368 5226-81032 10013196 D

ATOM 13464 N PROD331 37725 12608 67114 1003518 D ATOM 13547 CA GLY D 342 67703 5769-81148 10013613 D

ATOM 13465 CD PRO D 331 38132 13904 -67674 1004122 D ATOM 13548 C GLYD342 68012 6276-82539 10013510 D

ATOM 13466 CA PRO D 331 38344 11516-67883 1003518 D ATOM 13549 0 GLYD342 68870 5721-83216 10012937 D

ATOM 13467 CB PROD331 39366 12237-68736 10018520 D ATOM 13550 N ASND343 67315 7323-82969 1008028 D

ATOM 13468 CG PRO D 331 38694 13481-69023 1004122 D ATOM 13551 CA ASN D 343 67544 7916-84288 1008669 D

ATOM 13469 C PRO D 331 38999 10502-66972 1003518 D ATOM 13552 CB ASN D 343 66475 8966-84599 10017153 D

ATOM 13470 O PROD331 39703 10861 66017 1003518 D ATOM 13553 CG ASN D 343 65068 8436-84434 10015133 D

ATOM 13471 N LYS D 332 38771 9226-67251 1004578 D ATOM 13554 ODl ASN D 343 64659 7502-85124 10015133

ATOM 13472 CA LYS D 332 39352 8164-66435 1004640 D D ATOM 13473 CB LYS D 332 38696 6833-66778 1009587 D ATOM 13555 ND2 ASN D 343 64316 9034-83514 10015133

ATOM 13474 CG LYS D 332 38880 6463-68226 1006741 D D

ATOM 13475 CD LYS D 332 38691 4986-68444 1006741 D ATOM 13556 C ASN D 343 68910 8600-84264 1008475 D

ATOM 13476 CE LYS D 332 39099 4589-69851 1006741 D ATOM 13557 O ASN D 343 69699 8388 -83345 I 007338 D

ATOM 13477 NZ LYS D 332 39023 3108 70026 1006741 D ATOM 13558 N GLU D 344 69188 9421-85271 10010832 D

ATOM 13478 C LYS D 332 40857 8067-66695 1004547 D ATOM 13559 CA GLU D 344 70454 10149-85332 10010832

ATOM 13479 O LYS D 332 41343 8511-67737 1004356 D D

ATOM 13480 N ASP D 333 41593 7487-65750 1005062 D ATOM 13560 CB GLU D 344 71589 9210-85749 10017562 D

ATOM 13481 CA ASP D 333 43031 7323-65917 1005008 D ATOM 13561 CG GLU D 344 72239 8519-84551 10015552 D

ATOM 13482 CB ASP D 333 43649 6720-64660 10013168 D ATOM 13562 CD GLU D 344 73243 7454 -84935 10015552 D

ATOM 13483 CG ASP D 333 44080 7770-63666 1009927 D ATOM 13563 OEl GLU D 344 72820 6367-85380 10015552

ATOM 13484 ODl ASP D 333 43372 8789 -63526 1009927 D D

ATOM 13485 OD2 ASP D 333 45125 7575-63012 1009927 D ATOM 13564 OE2 GLU D 344 74457 7705-84792 10015552

ATOM 13486 C ASP D 333 43294 6406-67108 1005393 D D

ATOM 134870 ASP D 333 42580 5429-67329 1005358 D ATOM 13565 C GLU D 344 70362 11362-86256 10010832 D

ATOM 13488 N THR D 334 44321 6727-67879 1004254 D ATOM 13566 O GLUD344 70288 11235-87480 10010832 D

ATOM 13489 CA THR D 334 44665 5921-69037 1004226 D ATOM 13567 N LEU D 345 70368 12541-85635 10019822 D

ATOM 13490 CB THR D 334 44161 6580-70340 1006831 D ATOM 13568 CA LEU D 345 70237 13817-86333 10019822 D

ATOM 13491 OGl THR D 334 42743 6435-70419 1005421 D ATOM 13569 CB LEU D 345 69861 14915-85323 10019050 D

ATOM 13492 CG2THRD334 44792 5944-71560 1005421 D ATOM 13570 CG LEU D 345 68540 14752-84547 10014329 D

ATOM 13493 C THR D 334 46169 5728-69117 1004870 D ATOM 13571 CDl LEU D 345 68316 15965-83647 10014329

ATOM 13494 0 THR D 334 46931 6695-69209 1004606 D D

ATOM 13495 N THR D 335 46589 4468-69087 1004652 D ATOM 13572 CD2LEUD345 67373 14598-85514 10014329

ATOM 13496 CA THR D 335 48003 4141-69158 1004631 D D

ATOM 13497 CB THR D 335 48240 2739-68682 1005895 D ATOM 13573 C LEU D 345 71413 14284-87199 10019822

ATOM 13498 OGl THR D 335 47526 2534-67460 1004831 D ATOM 13574 O LEU D 345 71679 15481-87305 10019822

ATOM 13499 CG2 THR D 335 49709 2532 -68435 1004831 D ATOM 13575 N GLU D 346 72112 13337-87815 10014713

ATOM 13500 C THR D 335 48588 4286-70555 1004717 D ATOM 13576 CA GLU D 346 73227 13627-88722 10014713

ATOM 13501 O THR D 335 48023 3822-71539 1004852 D D

ATOM 13502 N PROD336 49754 4915-70656 1004540 D ATOM 13577 CB GLU D 346 72695 14427-89909 10014532

ATOM 13503 CD PRO D 336 50565 5515-69583 1003116 D D

ATOM 13504 CA PRO D 336 50385 5112-71957 1004498 D ATOM 13578 CG GLU D 346 71369 13886-90403 10013075

ATOM 13505 CB PRO D 336 51277 6312-71707 1004002 D D

ATOM 13506 CG PRO D 336 51812 5970-70335 1003116 D ATOM 13579 CD GLU D 346 71044 14310-91815 10013075 ATOM 13507 C PROD336 51197 3925-72456 1004502 D D

ATOM 13508 O PROD336 51386 2934-71754 1004565 D ATOM 13580 OEl GLU D 346 71764 13880-92740 10013075

ATOM 13509 N THR D 337 51680 4069-73684 1005657 D D

ATOM 13510 CA THR D 337 52513 3090-74349 1006003 D ATOM 13581 OE2GLUD346 70070 15071 -92002 10013075

ATOM 13511 CB THR D 337 51960 2765-75738 10011237 D D

ATOM 13512 OGl THR D 337 50783 1968-75603 1006326 D ATOM 13582 C GLUD346 74508 14287-88194 10014713 D

ATOM 13513 CG2THRD337 52979 2017-76565 1006326 D ATOM 13583 O GLU D 346 75533 13618-88062 10014713 D

ATOM 13514 C THR D 337 53835 3819-74508 1006760 D ATOM 13584 N ASP D 347 74466 15587-87909 10016259 D

ATOM 13515 O THR D 337 53865 4965 74963 1005898 D ATOM 13585 CA ASP D 347 75660 16283-87420 10016259 D

ATOM 13516 N VALD338 54930 3178-74131 1004711 D ATOM 13586 CB ASP D 347 75388 17786-87269 10017329 D

ATOM 13517 CA VAL D 338 56218 3841 -74259 1005397 D ATOM 13587 CG ASP D 347 74718 18134 85951 10017329 D ATOM 13518 CB VAL D 338 56903 4017 72882 1005174 D ATOM 13588 ODl ASP D 347 73589 17659-85713 10017329

ATOM 13519 CGl VAL D 338 58121 4938-73018 1005136 D D

ATOM 13520 CG2 VAL D 338 55915 4587-71886 1005136 D ATOM 13589 OD2ASPD347 75325 18883-85153 10017329

ATOM 13521 C VAL D 338 57155 3082-75176 1005844 D D

ATOM 13522 O VAL D 338 57107 1856-75236 1005827 D ATOM 13590 C ASP D 347 76179 15720 86092 10016259 D

ATOM 13523 N LYS D 339 57992 3832-75891 1006828 D ATOM 13591 O ASP D 347 77391 15647-85869 10016259 D

ATOM 13524 CA LYS D 339 58978 3285-76816 1006616 D ATOM 13592 N GLY D 348 75257 15332-85214 10011712 D

ATOM 13525 CB LYS D 339 58357 3083 -78203 10013080 D 65251/C766

ATOM 13593 CA GLY D 348 75638 14773 -83929 10011443 D ATOM 13678 CZ PHE D 359 51321 12554-72010 1004146 D

ATOM 13594 C GLY D 348 75591 13256-83954 10011139 D ATOM 13679 C PHE D 359 46894 9780 -70797 1003964 D

ATOM 13595 O GLY D 348 74764 12667-84652 10010640 D ATOM 13680 O PHE D 359 46831 10860-71384 1003719 D

ATOM 13596 N ASN D 349 76473 12619-83188 10020084 D ATOM 13681 N TYR D 360 46092 9499 -69765 10010628 D

ATOM 13597 CA ASN D 349 76524 11164 83151 10020084 D ATOM 13682 CA TYR D 360 45155 10548-69409 10010606

ATOM 13598 CB ASN D 349 77495 10686-82059 10017683 D D

ATOM 13599 CG ASN D 349 77488 11574-80831 10016201 D ATOM 13683 CB TYR D 360 43849 10091-68763 10015725 D

ATOM 13600 ODl ASN D 349 77827 12758-80896 10016201 D ATOM 13684 CG TYR D 360 43115 11348-68287 1004439 D

ATOM 13601 ND2 ASN D 349 77109 11001-79697 10016201 D ATOM 13685 CDl TYR D 360 42997 12465 69129 1004439

ATOM 13602 C ASN D 349 75159 10488-82996 10020084 D D

ATOM 13603 O ASN D 349 74552 10101 -83991 10020084 D ATOM 13686 CEl TYR D 360 42509 13692 -68654 1004439 D

ATOM 13604 N MET D 350 74664 10362-81769 10014327 D ATOM 13687 CD2 TYR D 360 42699 11493 66956 1004439

ATOM 13605 CA MET D 350 73380 9698-81550 10013936 D D

ATOM 13606 CB MET D 350 73613 8416-80741 10017314 D ATOM 13688 CE2TYRD360 42198 12717 -66474 1004439 D

ATOM 13607 CG MET D 350 72358 7624-80425 10012782 D ATOM 13689 CZ TYR D 360 42111 13812-67328 1004439 D

ATOM 13608 SD MET D 350 72718 6067 -79592 10012782 D ATOM 13690 OH TYR D 360 41639 15029-66867 1004439 D

ATOM 13609 CE MET D 350 72523 4917-80958 10012782 D ATOM 13691 C TYR D 360 45642 11691 -68566 10010715 D

ATOM 13610 C MET D 350 72307 10555-80868 10013650 D ATOM 13692 O TYR D 360 45937 12748-69106 10011308 D

ATOM 13611 O MET D 350 72617 11517-80169 10013293 D ATOM 13693 N PRO D 361 45702 11525-67237 1005484 D

ATOM 13612 N THR D 351 71042 10194-81087 1007786 D ATOM 13694 CD PRO D 361 45877 10301 -66439 1003245 D

ATOM 13613 CA THR D 351 69904 10896 80489 1007582 D ATOM 13695 CA PRO D 361 46175 12732-66537 1005043 D

ATOM 13614 CB THR D 351 69199 11806-81512 1008165 D ATOM 13696 CB PRO D 361 46491 12228-65126 1003169 D

ATOM 13615 OGl THR D 351 68669 12941 -80837 1004877 D ATOM 13697 CG PRO D 361 46798 10777 -65330 1003245 D

ATOM 13616 CG2THRD351 68028 11 103 82164 1004877 D ATOM 13698 C PRO D 361 47349 13253-67361 1005783 D

ATOM 13617 C THR D 351 68871 9903 -79941 1007005 D ATOM 13699 O PRO D 361 48372 12600-67501 1005500 D

ATOM 13618 O THR D 351 68506 8934-80611 1006164 D ATOM 13700 N PRO D 362 47160 14421 -67991 1003569 D

ATOM 13619 N LEU D 352 68400 10141 78722 1007384 D ATOM 13701 CD PRO D 362 45976 15277-67770 1002651 D

ATOM 13620 CA LEU D 352 67410 9259-78113 1007686 D ATOM 13702 CA PRO D 362 48138 15094-68857 1002940 D

ATOM 13621 CB LEU D 352 67874 8803-76737 1009571 D ATOM 13703 CB PRO D 362 47381 16347-69322 1002651 D

ATOM 13622 CG LEU D 352 68890 7666 -76838 1007677 D ATOM 13704 CG PRO D 362 46477 16637-68182 1002651 D

ATOM 13623 CDl LEU D 352 69546 7407 -75495 1007677 D ATOM 13705 C PRO D 362 49526 15397-68317 1003200 D

ATOM 13624 CD2 LEU D 352 68183 6424-77337 1007677 D ATOM 13706 O PRO D 362 50439 15702-69085 1003676 D

ATOM 13625 C LEU D 352 66068 9944 -78009 1007354 D ATOM 13707 N ASP D 363 49685 15315-67001 1003669 D

ATOM 13626 O LEU D 352 65978 11114-77627 1006916 D ATOM 13708 CA ASP D 363 50984 15581 -66399 1003654 D

ATOM 13627 N GLU D 353 65022 9207 -78357 1006989 D ATOM 13709 CB ASP D 363 50847 15992-64913 1006057 D

ATOM 13628 CA GLU D 353 63673 9750-78337 1006614 D ATOM 13710 CG ASP D 363 49899 15091-64117 1005478 D

ATOM 13629 CB GLU D 353 63170 9932-79767 10013282 D ATOM 13711 ODl ASP D 363 48711 14962-64510 1005478 D

ATOM 13630 CG GLU D 353 61788 10520-79861 1009137 D ATOM 13712 OD2 ASP D 363 50340 14526-63084 1005478 D

ATOM 13631 CD GLU D 353 61303 10583-81283 1009137 D ATOM 13713 C ASP D 363 51879 14364-66549 1004008 D

ATOM 13632 OEl GLU D 353 61999 11197-82122 1009137 D ATOM 13714 O ASP D 363 51515 13256-66155 1003658 D

ATOM 13633 OE2GLUD353 60229 10016-81564 1009137 D ATOM 13715 N VAL D 364 53031 14569-67171 1003651 D

ATOM 13634 C GLU D 353 62715 8852-77566 1006939 D ATOM 13716 CA VAL D 364 53993 13504-67357 1003883 D

ATOM 13635 O GLU D 353 62439 7726-77961 1007017 D ATOM 13717 CB VAL D 364 53893 12865-68745 1005588 D

ATOM 13636 N CYS D 354 62216 9367-76454 1005562 D ATOM 13718 CGl VAL D 364 55154 12144-69064 1003427

ATOM 13637 CA CYS D 354 61280 8647 -75609 1005590 D D

ATOM 13638 C CYS D 354 59899 9150-75989 1005699 D ATOM 13719 CG2 VAL D 364

ATOM 13639 O CYS D 354 59633 10359-75922 1005569 D D

ATOM 13640 CB CYS D 354 61552 8990-74152 10010885 D ATOM 13720 C VAL D 364 55364 14108-67210 1004617 D

ATOM 13641 SG CYS D 354 60768 7904 -72923 1008604 D ATOM 13721 O VAL D 364 55601 15236-67647 1003791 D

ATOM 13642 N THR D 355 59021 8251 -76414 1006531 D ATOM 13722 N ILE D 365 56258 13373-66567 1005133 D

ATOM 13643 CA THR D 355 57682 8691 -76773 1005467 D ATOM 13723 CA ILE D 365 57613 13847-66405 1004538 D

ATOM 13644 CB THR D 355 57365 8481 -78273 1009266 D ATOM 13724 CB ILE D 365 57899 14317-64981 1004977 D

ATOM 13645 OGl THR D 355 56613 7281 -78427 1004181 D ATOM 13725 CG2 ILE D 365 59376 14609 -64825 1002621 D

ATOM 13646 CG2 THR D 355 58626 8364-79091 1004181 D ATOM 13726 CGl ILE D 365 57091 15590-64705 1002621 D

ATOM 13647 C THR D 355 56647 7952 -75939 1006816 D ATOM 13727 CDl ILE D 365 57280 16167-63334 1002621 D

ATOM 13648 O THR D 355 56645 6718-75873 1006096 D ATOM 13728 C ILE D 365 58540 12731 66800 1005214 D

ATOM 13649 N VAL D 356 55779 8727-75295 1004081 D ATOM 13729 O ILE D 365 58260 11549 -66590 1005291 D

ATOM 13650 CA VAL D 356 54729 8192-74444 1003653 D ATOM 13730 N THR D 366 59656 13133 -67384 1005543 D

ATOM 13651 CB VAL D 356 54761 8892 -73075 1006904 D ATOM 13731 CA THR D 366 60628 12202-67893 1006371 D

ATOM 13652 CGl VAL D 356 53872 8173-72095 1005357 D ATOM 13732 CB THR D 366 60613 12292-69431 1005926 D

ATOM 13653 CG2 VAL D 356 56181 8918-72555 1005357 D ATOM 13733 OGl THR D 366 60314 11008-69972 1004694

ATOM 13654 C VAL D 356 53399 8432-75156 1004537 D D

ATOM 13655 O VAL D 356 53030 9570 -75448 1004648 D ATOM 13734 CG2 THR D 366

ATOM 13656 N ASN D 357 52683 7348-75431 1005470 D D

ATOM 13657 CA ASN D 357 51434 7441 76167 1005092 D ATOM 13735 C THR D 366 62021 12463 -67362 1007269 D

ATOM 13658 CB ASN D 357 51432 6431 -77303 10011935 D ATOM 13736 O THR D 366 62465 13604-67298 1007193 D

ATOM 13659 CG ASN D 357 52495 6722-78313 1007327 D ATOM 13737 N LYS D 367 62703 11391 -66977 1004975 D

ATOM 13660 ODl ASN D 357 52572 7826 -78837 1007327 D ATOM 13738 CA LYS D 367 64071 11482-66483 1005295 D

ATOM 13661 ND2 ASN D 357 53334 5741 -78590 1007327 D ATOM 13739 CB LYS D 367 64157 11089-65010 1005666 D

ATOM 13662 C ASN D 357 50134 7329-75411 1005508 D ATOM 13740 CG LYS D 367 63577 12118-64074 1004767 D

ATOM 13663 O ASN D 357 49903 6383 -74660 1005796 D ATOM 13741 CD LYS D 367 63894 11823 -62612 1004767 D

ATOM 13664 N SER D 358 49283 8319-75676 1005537 D ATOM 13742 CE LYS D 367 63472 12996 61752 1004767 D

ATOM 13665 CA SER D 358 47961 8476-75091 1006267 D ATOM 13743 NZ LYS D 367 64043 12910-60391 1004767 D

ATOM 13666 CB SER D 358 46909 7819-75988 1006302 D ATOM 13744 C LYS D 367 64983 10568-67283 1005565 D

ATOM 13667 OG SER D 358 47089 6431 -76016 1006136 D ATOM 13745 O LYS D 367 64668 9394-67481 1005596 D

ATOM 13668 C SER D 358 47800 8009 -73646 1006739 D ATOM 13746 N TRP D 368 66101 11119-67755 1005265 D

ATOM 13669 O SER D 358 47468 6851 -73372 1006294 D ATOM 13747 CA TRP D 368 67092 10345 -68500 1005271 D

ATOM 13670 N PHE D 359 48033 8955 -72737 1003874 D ATOM 13748 CB TRP D 368 67593 11128 -69710 1006737 D

ATOM 13671 CA PHE D 359 47919 8754-71284 1003305 D ATOM 13749 CG TRP D 368 66555 11263 -70766 1004729 D

ATOM 13672 CB PHE D 359 49292 9003 -70629 1004686 D ATOM 13750 CD2 TRP D 368 66265 10323-71802 1004729 D

ATOM 13673 CG PHE D 359 49989 10253-71115 1004146 D ATOM 13751 CE2 TRP D 368 65168 10832-72531 1004729 D

ATOM 13674 CDl PHE D 359 49692 11495 -70568 1004146 D ATOM 13752 CE3 TRP D 368 66822 9097 -72184 1004729 D

ATOM 13675 CD2 FHE D 359 50957 10179-72118 1004146 D ATOM 13753 CDl TRP D 368 65654 12272-70902 1004729 D

ATOM 13676 CEl PHE D 359 50351 12641 -71008 1004146 D ATOM 13754 NEl TRP D 368 64816 12023-71959 1004729 D

ATOM 13677 CE2 PHE D 359 51623 11326-72567 1004146 D ATOM 13755 CZ2 TRP D 368 64615 10159-73627 1004729 D 65251/C766

ATOM 13756 CZ3 TRP D 368 66272 8 423 -73 273 1 004729 D ATOM 13841 CD2 TYR D 378 67530 -0648 -66995 1007052 D

ATOM 13757 CH2 TRP D 368 65 179 8 959 -73 983 1 00 4729 D ATOM 13842 CE2 TYR D 378 68789 -0568 -67582 1007052 D

ATOM 13758 C TRP D 368 68258 10 024 -67 569 00 54 66 D ATOM 13843 CZ TYR D 378 69467 -1724 -67897 1007052 D

ATOM 13759 O TRP D 368 68 954 10924 -67 094 00 54 85 D ATOM 13844 OH TYR D 378 70725 -1635 -68441 1007052 D

ATOM 13760 N ILE D 369 68461 3 737 -67307 1 0044 25 D ATOM 13845 C TYR D 378 64474 -1414 -63827 1007889 D

ATOM 13761 CA ILE D 369 69 519 8 287 -66 411 00 45 62 D ATOM 13846 O TYR D 378 63413 -1442 -64453 1007889 D

ATOM 13762 CB ILE D 369 68 902 7 668 -65 162 1 006679 D ATOM 13847 N LYS D 379 64573 -1041 -62555 1005693 D

ATOM 13763 CG2 ILE D 369 69 979 7274 64 189 1 004447 D ATOM 13848 CA LYS D 379 63452 -0585 -61747 1005693 D

ATOM 13764 CGl ILE D 369 67 945 8 669 -64 521 1 0044 47 D ATOM 13849 CB LYS D 379 63054 -1634 -60710 1009114 D

ATOM 13765 CDl ILE D 369 67 166 8 100 -63 374 1 0044 47 D ATOM 13850 CG LYS D 379 62465 -2901 -61285 1009114 D

ATOM 13766 C ILE D 369 70 417 7252 -67076 1 004744 D ATOM 13851 CD LYS D 379 62128 -3876-601701009114 D

ATOM 13767 O ILE D 369 69 931 5329 -67726 1 0044 24 D ATOM 13852 CE LYS D 379 61705 -5240 60700 1009114 D

ATOM 13768 N GLU D 370 71 728 7407 -66 922 00 53 66 D ATOM 13853 NZ LYS D 379 61557 -6228 -59583 1009114 D

ATOM 13769 CA GLU D 370 72 655 6454 -67 512 1 00 5631 D ATOM 13854 C LYS D 379 63950 0681 -61038 1005693 D

ATOM 13770 CB GLU D 370 74090 6 885 -67227 1 00123 61 D ATOM 13855 O LYS D 379 65090 074060573 1005693 D

ATOM 13771 CG GLU D 370 74 519 8 032 -68 119 1 00102 25 D ATOM 13856 N TYR D 380 63102 1703-60983 1005233 D

ATOM 13772 CD GLU D 370 75 824 8 653 -67 698 1 00102 25 D ATOM 13857 CA TYR D 380 63453 2956 -60324 1005233 D

ATOM 13773 OEl GLU D 370 76 79 7 897 -67 454 1 00102 25 D ATOM 13858 CB TYR D 380 62681 4099-60961 1004036 D

ATOM 13774 OE2 GLU D 370 75 88: 9 901 -67 622 1 00102 25 D ATOM 13859 CG TYR D 380 63054 5448 -604261004036 D

ATOM 13775 C GLU D 370 72 353 5 067 -66 949 00 56 49 D ATOM 13860 CDl TYR D 380 64119 6165-60976 1004036 D

ATOM 13776 O GLU D 370 72 185 4907 -65 738 00 55 34 D ATOM 13861 CEl TYR D 380 64448 7429-60508 1004036 D

ATOM 13777 N SER D 371 72 265 4 071 -67 829 1 004776 D ATOM 13862 CD2 TYR D 380 62328 6028-59380 1004036 D

ATOM 13778 CA SER D 371 71 938 2 708 -67416 1 0048 30 D ATOM 13863 CE2 TYR D 380 62647 7298-58900 1004036 D

ATOM 13779 CB SER D 371 71 873 1 799 68 636 1 00 72 01 D ATOM 13864 CZ TYR D 380 63705 7994 -59472 1004036 D

ATOM 13780 OG SER D 371 73 108 1 804 -69 317 1 00 61 09 D ATOM 13865 OH TYR D 380 63987 9266-59033 1004036 D

ATOM 13781 C SER D 371 72 843 2 067 -66369 1 004757 D ATOM 13866 C TYR D 380 63054 2829 -58862 1005233 D

ATOM 13782 O SER D 371 72416 1 141 65 673 1 0048 51 D ATOM 13867 O TYR D 380 61871 2783-58542 1005233 D

ATOM 13783 N GLU D 372 74 088 2 534 -66 265 00 56 33 D ATOM 13868 N VAL D 381 64035 2766 -57976 1004505 D

ATOM 13784 CA GLU D 372 75 021 1 984 -65 283 1 00 54 88 D ATOM 13869 CA VAL D 381 63754 2617-56556 1004505 D

ATOM 13785 CB GLU D 372 76342 2 753 -65 309 1 00116 17 D ATOM 13870 CB VAL D 381 64959 1995 -55823 1002593 D

ATOM 13786 CG GLU D 372 76 186 4 238 -65 047 1 00116 17 D ATOM 13871 CGl VAL D 381 64620 1760 -54358 1002593 D

ATOM 13787 CD GLU D 372 77502 4 922 -64 748 1 00116 17 D ATOM 13872 CG2 VAL D 381 65326 0687-56504 1002593 D

ATOM 13788 OEl GLU D 372 78 13: 4 560 -63 735 1 00116 17 D ATOM 13873 C VAL D 381 63407 3963 -55928 I 004505 D

ATOM 13789 OE2 GLU D 372 77 90. 5 820 -65 520 1 00116 17 D ATOM 13874 O VAL D 381 64212 4895 55949 1004505 D

ATOM 13790 C GLU D 372 74 416 2 064 -63 879 00 5949 D ATOM 13875 N ASN D 382 62214 4046-55348 1007031 D

ATOM 13791 O GLU D 372 74 554 1 141 -63 074 00 60 56 D ATOM 13876 CA ASN D 382 61734 5285-54756 1007031 D

ATOM 13792 N HIS D 373 73 724 3 168 -63 604 1 00 73 85 D ATOM 13877 CB ASN D 382 60613 5013-53775 1004043 D

ATOM 13793 CA HIS D 373 73 107 3 401 -62 308 00 7734 D ATOM 13878 CG ASN D 382 59714 6221-535671004043 D

ATOM 13794 CB HIS D 373 72 576 4 821 -62 244 00 85 76 D ATOM 13879 ODl ASN D 382 60146 7372-53659 1004043 D

ATOM 13795 CG HIS D 373 73 641 5 857 -62 383 00 55 11 D ATOM 13880 ND2 ASN D 382 58448 5952-53264 1004043 D

ATOM 13796 CD2 HIS D 373 73 759 6907 -63 232 1 00 55 11 D ATOM 13881 C ASN D 382 62756 6168-54064 1007031 D

ATOM 13797 NDl HIS D 373 74 756 5 890 -61 573 1 00 55 11 D ATOM 13882 O ASN D 382 63223 7145-54644 1007031 D

ATOM 13798 CEl HIS D 373 75 517 6 917 -61 916 1 00 55 1 1 D ATOM 13883 N GLY D 383 63116 5859-52826 1003201 D

ATOM 13799 NE2 HIS D 373 74 934 7 551 -62 921 1 00 55 11 D ATOM 13884 CA GLY D 383 64059 6752-52162 1003201 D

ATOM 13800 C HIS D 373 72 005 2431 -61 925 1 00 73 11 D ATOM 13885 C GLY D 383 65515 6774-52633 1003201 D

ATOM 13801 O HIS D 373 71 524 2457 60801 1 00 68 95 D ATOM 13886 O GLY D 383 66331 7493 -52078 1003201 D

ATOM 13802 N PHE D 374 71 589 1 575 -62 843 1 00 55 67 D ATOM 13887 N ARG D 384 65856 5993-53651 1005361 D

ATOM 13803 CA PHE D 374 70 558 0 618 -62 499 1 00 56 44 D ATOM 13888 CA ARG D 384 67239 5938-54106 1005361 D

ATOM 13804 CB PHE D 374 69 527 0498 -63 615 1 00 65 54 D ATOM 13889 CB ARG D 384 67446 4699 -54987 1005460 D

ATOM 13805 CG PHE D 374 68 632 1 683 -63 714 1 00 45 72 D ATOM 13890 CG ARG D 384 68902 4409 -55360 1005460 D

ATOM 13806 CDl PHE D 374 69 045 2 827 -64 384 1 0045 72 D ATOM 13891 CD ARG D 384 69025 2987 -55897 1005460 D

ATOM 13807 CD2 PHE D 374 67411 1 697 -63 064 1 0045 72 D ATOM 13892 NE ARG D 384 68612 2023-54885 1005460 D

ATOM 13808 CEl PHE D 374 68 255 3 968 -64398 1 0045 72 D ATOM 13893 CZ ARG D 384 68432 0733-55110 1005460 D

ATOM 13809 CE2 PHE D 374 66619 2 832 -63 073 1 0045 72 D ATOM 13894 NHl ARG D 384 68626 0235 -563201005460 D

ATOM 13810 CZ PHE D 374 67 042 3 970 -63 739 1 00 45 72 D ATOM 13895 NH2 ARG D 384 68058 -0055-54118 1005460

ATOM 13811 C PHE D 374 71 146 0 744 -62 176 1 0052 52 D D

ATOM 13812 O PHE D 374 70417 -1 737 -62 052 1 005076 D ATOM 13896 C ARG D 384 67681 7180-54848 1005361 D

ATOM 13813 N LYS D 375 72467 -0 777 -62 021 1 009843 D ATOM 13897 O ARG D 384 66887 7842-55508 1005361 D

ATOM 13814 CA LYS D 375 73 194 -1 998 -61 694 1 00101 06 D ATOM 13898 N TYR D 385 68961 7494 -54733 1005259 D

ATOM 13815 CB LYS D 375 73 485 -2 059 -60 188 1 00139 61 D ATOM 13899 CA TYR D 385 69532 8640 -55420 1005259 D

ATOM 13816 CG LYS D 375 74 673 -1 228 -59 713 1 00113 45 D ATOM 13900 CB TYR D 385 70745 9142 -54664 1006153 D

ATOM 13817 CD LYS D 375 74403 0264 -59772 1 0011345 D ATOM 13901 CG TYR D 385 7148410201 -55423 1006153 D

ATOM 13818 CE LYS D 375 75 568 1 060 -59 181 1 00113 45 D ATOM 13902 CDl TYR D 385 70995 11503-55495 1006153

ATOM 13819 NZ LYS D 375 75 374 2 545 -59 263 1 00113 45 D D

ATOM 13820 C LYS D 375 72488 3 286 62 115 1 0010608 D ATOM 13903 CEl TYR D 385 71628 12474-56271 1006153 D

ATOM 13821 O LYS D 375 72256 -4 166 -61 289 1 00108 34 D ATOM 13904 CD2 TYR D 385 72632 9893 -56142 1006153 D

ATOM 13822 N GLY D 376 72 133 -3 391 -63 391 00 82 14 D ATOM 13905 CE2 TYR D 385 73274 10855-56924 1006153 D

ATOM 13823 CA GLY D 376 71 489 4 605 -63 869 1 00 82 14 D ATOM 13906 CZ TYR D 385 72762 12142-56982 1006153 D

ATOM 13824 C GLY D 376 69 981 -4 742 -63 713 00 82 14 D ATOM 13907 OH TYR D 385 73367 13100-57759 1006153 D

ATOM 13825 O GLY D 376 69334 -5 418 -64 519 00 82 14 D ATOM 13908 C TYR D 385 69968 8272 -56847 1005259 D

ATOM 13826 N GLU D 377 69409 -4 134 -62 680 00 88 59 D ATOM 13909 O TYR D 385 70493 7180-57080 1005259 D

ATOM 13827 CA GLU D 377 67 968 -4218 -62 480 1 00 88 59 D ATOM 13910 N TYR D 386 69759 9183 57797 1004889 D

ATOM 13828 CB GLU D 377 67 642 -4474 61 009 1 00126 99 D ATOM 13911 CA TYR D 386 70147 8947-59188 1004889 D

ATOM 13829 CG GLU D 377 66 181 -4 816 -60761 1 0012699 D ATOM 13912 CB TYR D 386 68974 8421-60025 1004390 D

ATOM 13830 CD GLU D 377 65 885 -5 102 -59 300 1 0012699 D ATOM 13913 CG TYR D 386 68409 7075 -59647 1004390 D

ATOM 13831 OEl GLU D 377 64 75! -5 545 -58 995 1 00126 99 D ATOM 13914 CDl TYR D 386 67298 6982 -588341004390 D

ATOM 13832 OE2 GLU D 377 66 78: -4 880 -58 457 1 00126 99 D ATOM 13915 CEl TYR D 386 66733 5752 -58524 I 004390 D

ATOM 13833 C GLU D 377 67325 -2 910 -62 934 00 88 59 D ATOM 13916 CD2 TYR D 386 68959 5894 -60147 1004390 D

ATOM 13834 O GLU D 377 67610 -1 848 -62 372 00 88 59 D ATOM 13917 CE2 TYR D 386 68402 4657 -59839 1004390 D

ATOM 13835 N TYR D 378 66457 -2 992 -63 944 0078 89 D ATOM 13918 CZ TYR D 386 67286 4601 -59023 1004390 D

ATOM 13836 CA TYR D 378 65 795 -1 808 -64478 1 00 78 89 D ATOM 13919 OH TYR D 386 66719 3401 -58688 1004390 D

ATOM 13837 CB TYR D 378 65 622 -1 943 -65 990 1 00 70 52 D ATOM 13920 C TYR D 386 70632 10211-59889 1004889 D

ATOM 13838 CG TYR D 378 66 941 -1 874 -66 715 1 00 70 52 D ATOM 13921 O TYR D 386 69930 11208-59912 1004889 D

ATOM 13839 CDl TYR D 378 67 63Ϊ -3 025 -67 048 1 00 70 52 D ATOM 13922 N PRO D 387 71850 10200-60452 1005854 D

ATOM 13840 CEl TYR D 378 68 896 -2 955 -67639 1 007052 D ATOM 13923 CD PRO D 387 72934 9220-602871009717 D 65251/C766

ATOM 13924 CA PRO D 387 72327 11400-61158 1005854 D ATOM 14009 C GLU D 396 60921 22618-63740 1004207 D ATOM 13925 CB PRO D 387 73743 11015-61555 1009717 D ATOM 14010 O GLU D 396 5974722984 -63657 1004207 D

ATOM 13926 CG PRO D 387 74156 10081-60456 1009717 D ATOM 14011 N PRO D 397 6124721366 -64103 1005148 D

ATOM 13927 C PRO D 387 71383 11427 -62359 1005854 D ATOM 14012 CD PRO D 397 62555 20695 -64148 1003262 D

ATOM 13928 O PRO D 387 71021 10353 62852 1005854 D ATOM 14013 CA PRO D 397 6016620414-64381 1005148 D

ATOM 13929 N GLU D 388 70980 12587-62870 1008517 D ATOM 14014 CB PRO D 397 60907 19091-64547 1003262 D ATOM 13930 CA GLU D 388 70014 12497-63955 1008517 D ATOM 14015 CG PRO D 397 62182 19303 -63782 1003262 D ATOM 13931 CB GLUD388 68611 12674-63372 10010041 D ATOM 14016 C PRO D 397 59162 20405-63231 1005148 D ATOM 13932 CG GLUD388 68313 14072-62869 10010041 D ATOM 14017 O PRO D 397 5954020376-62053 1005148 D ATOM 13933 CD GLUD388 66844 14271 -62563 10010041 D ATOM 14018 N GLY D 398 5788420439 -63575 1004665 D ATOM 13934 OEl GLU D 388 66023 14090-63487 10010041 D ATOM 14019 CA GLY D 398 5685220495 -62556 1004665 D

ATOM 13935 OE2GLUD388 66509 14608-61407 10010041 D ATOM 14020 C GLY D 398 5609021806 -62728 1004665 D

ATOM 13936 C GLU D 388 70049 13251 -65277 1008517 D ATOM 14021 O GLY D 398 54859 21842 -62599 1004665 D

ATOM 139370 GLU D 388 69009 13340-65926 1008517 D ATOM 14022 N GLU D 399 5682022886 -63020 1003601 D

ATOM 13938 N TRP D 389 71180 13783-65720 1007099 D ATOM 14023 CA GLU D 399 56198 24187 -63240 1003601 D

ATOM 13939 CA TRP D 389 71159 14470-67021 1007099 D ATOM 14024 CB GLU D 399 5725325296-63263 1005198 D

ATOM 13940 CB TRP D 389 70905 13463 68147 10011099 D ATOM 14025 CG GLU D 399 58146 25329-62028 1005198 D

ATOM 13941 CG TRP D 389 72115 12964-68861 10011099 D ATOM 14026 CD GLU D 399 59163 26485 -62024 1005198 D ATOM 13942 CD2TRPD389 73466 13436 68728 10011099 D ATOM 14027 OEl GLU D 399 59781 26747-63078 1005198 ATOM 13943 CE2TRPD389 74257 12689-69629 10011099 D D ATOM 13944 CE3TRPD389 74086 14420-67936 10011099 D ATOM 14028 OE2 GLU D 399 ATOM 13945 CD1 TRPD389 72146 11982-69806 10011099 D D

ATOM 13946 NEl TRP D 389 73425 11810-70272 10011099 D ATOM 14029 C GLU D 399 5550924101 -64601 1003601 D ATOM 13947 CZ2TRPD389 75638 12893-69763 10011099 D ATOM 14030 O GLU D 399 56073 23536 -65541 1003601 D ATOM 13948 CZ3 TRP D 389 75459 14621-68069 10011099 D ATOM 14031 N PRO D 400 54275 24632 -64730 1005731 D ATOM 13949 CH2TRPD389 76218 13859-68978 10011099 D ATOM 14032 CD PRO D 400 53376 25243 -63744 1003959 D

ATOM 13950 C TRP D 389 70065 15543-67105 1007099 D ATOM 14033 CA PRO D 400 53625 24541 -66043 1005239 D

ATOM 13951 O TRP D 389 69077 15366-67830 1007099 D ATOM 14034 CB PRO D 400 52275 25222 -65822 1008820 D

ATOM 13952 N GLY D 390 70240 16648-66382 1008135 D ATOM 14035 CG PRO D 400 52489 26061 -64630 I 003959 D ATOM 13953 CA GLY D 390 69236 17698-66399 1008135 D ATOM 14036 C PRO D 400 54432 25150-67191 1004314 D

ATOM 13954 C GLY D 390 69015 18346-67756 1008135 D ATOM 14037 O PRO D 400 54225 24817-68357 1004335 D

ATOM 13955 O GLY D 390 69900 18349-68606 1008135 D ATOM 14038 N GLY D 401 5537926016-66861 1006013 D ATOM 13956 N ARG D 391 67818 18886 67963 1009182 D ATOM 14039 CA GLY D 401 56195 26624 -67894 1005969 D

ATOM 13957 CA ARG D 391 67478 19574-69205 1009182 D ATOM 14040 C GLY D 401 57245 25712-68518 1005948 D ATOM 13958 CB ARG D 391 65986 19402-69511 1009474 D ATOM 14041 O GLY D 401 57842 26067 -69527 1006019 D ATOM 13959 CG ARG D 391 65540 17945 -69647 I 009474 D ATOM 14042 N PHE D 402 5749024544 -67937 1005179 D ATOM 13960 CD ARG D 391 65497 17467-71110 1009474 D ATOM 14043 CA PHE D 402 5848823637 -68494 I 005179 D ATOM 13961 NE ARGD391 64188 17678-71741 1009474 D ATOM 14044 CB PHE D 402 5873622470-67555 10015930 D ATOM 13962 CZ ARG D 391 63735 18848-72191 1009474 D ATOM 14045 CG PHE D 402 60041 21804-67793 1005763 D ATOM 13963 NHl ARG D 391 64483 19942-72095 1009474 D ATOM 14046 CDl PHE D 402 61221 22408-67370 1005763 D ATOM 13964 NH2 ARG D 391 62524 18927-72731 1009474 D ATOM 14047 CD2 PHE D 402 60112 20602 -68498 1005763 D

ATOM 13965 C ARGD391 6780521051-68972 1009182 D ATOM 14048 CEl PHE D 402 6246021831 -67647 1005763 D

ATOM 13966 O ARG D 391 6804021462-67839 1009182 D ATOM 14049 CE2 PHE D 402 61344 20012-68781 1005763 D

ATOM 13967 N LYS D 392 6783221848 -70032 1006153 D ATOM 14050 CZ PHE D 402 62523 20631 -68354 1005763 D

ATOM 13968 CA LYS D 392 6814223270 -69886 1006153 D ATOM 14051 C PHE D 402 58049 23091 -69858 1005179 D

ATOM 13969 CB LYS D 392 69275 23670-70834 1009851 D ATOM 14052 O PHE D 402 56942 22562 -69997 1005179 D

ATOM 13970 CG LYS D 392 69655 25143-70740 1009851 D ATOM 14053 N PRO D 403 5892623191-70877 1006831 D ATOM 13971 CD LYS D 392 7060625556-71851 1009851 D ATOM 14054 CD PRO D 403 6026923771 -70771 1005631 D

ATOM 13972 CE LYS D 392 7083627058 -71838 1009851 D ATOM 14055 CA PRO D 403 5868422735-72251 1006831 D

ATOM 13973 NZ LYS D 392 71619 27508-73024 1009851 D ATOM 14056 CB PRO D 403 59883 23285 -73025 10016114 D

ATOM 13974 C LYS D 392 6691424142-70165 1006153 D ATOM 14057 CG PRO D 403 60452 24329 -72138 1005631 D

ATOM 13975 O LYS D392 6640624169 -71284 1006153 D ATOM 14058 C PRO D 403 58596 21224-72399 1006831 D

ATOM 13976 N SER D 393 6644924855 -69142 1005524 D ATOM 14059 O PRO D 403 5961420541 -72382 1006831 D

ATOM 13977 CA SER D 393 6527725722-69263 1005524 D ATOM 14060 N TRP D 404 57385 20699 -72522 1006052 D

ATOM 13978 CB SER D 393 6400024889 69292 1006130 D ATOM 14061 CA TRP D 404 57198 19272 -72737 1006052 D ATOM 13979 OG SERD393 6285625718-69288 1006130 D ATOM 14062 CB TRP D 404 56346 18636 -71640 1005478 D

ATOM 13980 C SER D 393 65212 26666-68081 1005524 D ATOM 14063 CG TRP D 404 57034 18441 -70337 1004802 D

ATOM 13981 O SER D 393 6578526383-67032 1005524 D ATOM 14064 CD2 TRP D 404 58173 17614-70074 1004802 D

ATOM 13982 N ASN D 394 64521 27790-68239 1006299 D ATOM 14065 CE2 TRP D 404 58442 17699-68690 1004802 D ATOM 13983 CA ASN D 394 64409 28734-67135 1006299 D ATOM 14066 CE3 TRP D 404 58994 16807-70871 1004802 D ATOM 13984 CB ASN D 394 63955 30094-67631 1006250 D ATOM 14067 CDl TRP D 404 56675 18978-69145 1004802 D ATOM 13985 CG ASN D 394 65024 30804-68412 1006250 D ATOM 14068 NEl TRP D 404 57511 18540-68148 1004802 D ATOM 13986 ODl ASN D 394 6616830914 -67962 1006250 D ATOM 14069 CZ2 TRP D 404 59498 17006-68082 1004802 D ATOM 13987 ND2 ASN D 394 64659 31303 -69594 1006250 D ATOM 14070 CZ3TRPD404 60050 16116-70266 1004802 D

ATOM 13988 C ASND394 6341928203-66116 1006299 D ATOM 14071 CH2 TRP D 404 60288 16222-68883 1004802 D

ATOM 13989 O ASN D 394 6339028634-64964 1006299 D ATOM 14072 C TRP D 404 56451 19191 -74061 1006052 D ATOM 13990 N TYR D 395 6260927254-66556 1005645 D ATOM 14073 O TRP D 404 55456 19892-74261 1006052 D

ATOM 13991 CA TYRD395 61621 26644-65698 1005645 D ATOM 14074 N ASN D 405 56931 18353-74971 1005938 D ATOM 13992 CB TYR D 395 60343 26387-66486 1004484 D ATOM 14075 CA ASN D 405 56280 18214-76262 1005941 D ATOM 13993 CG TYR D 395 5965727628-66978 1004484 D ATOM 14076 CB ASN D 405 57250 17611 -77271 1009150 D ATOM 13994 CDl TYR D 395 59878 28106 -68264 1004484 D ATOM 14077 CG ASN D 405 56858 17913-78690 1009150 D ATOM 13995 CEl TYR D 395 59240 29256-68728 1004484 D ATOM 14078 ODl ASN D 405 55874 17381-79207 1009150 ATOM 13996 CD2 TYR D 395 58777 28333-66153 1004484 D D ATOM 13997 CE2 TYR D 395 58136 29481-66601 1004484 D ATOM 14079 ND2 ASN D 405 ATOM 13998 CZ TYR D 395 5837429940-67897 1004484 D D ATOM 13999 OH TYR D 395 57749 31088 -68355 1004484 D ATOM 14080 C ASN D 405 55032 17341-76132 1006835 D

ATOM 14000 C TYR D 395 62163 25320-65185 1005645 D ATOM 14081 O ASN D 405 55016 16174-76531 1006141 D ATOM 14001 O TYRD395 6302524719-65822 1005645 D ATOM 14082 N ILE D 406 53985 17918-75559 1 006297 D

ATOM 14002 N GLU D 396 6165324873 -64038 1004207 D ATOM 14083 CA ILE D 406 52733 17204-75370 1005517 D ATOM 14003 CA GLU D 396 6205423600 -63444 1004207 D ATOM 14084 CB ILE D 406 52242 17317-73909 1006364 D ATOM 14004 CB GLU D 396 6220423740 -61932 10011994 D ATOM 14085 CG2 ILE D 406 50995 16465-73700 1005126 D ATOM 14005 CG GLU D 396 63021 24930-61487 10011994 D ATOM 14086 CGl ILE D 406 53356 16867-72962 1005126 D ATOM 14006 CD GLU D 396 62916 25160-59993 10011994 D ATOM 14087 CDl ILE D 406 52957 16862-71499 1005126 D ATOM 14007 OEl GLU D 396 6177425265 -59491 10011994 D ATOM 14088 C ILE D 406 51669 17782-76285 1006204 D ATOM 14008 OE2GLUD396 63968 25240-59323 10011994 D ATOM 14089 O ILE D 406 51623 18985-76511 1005714 D 65251/C766

ATOM 14090 N LYS D 407 50827 16916-76827 1004222 D ATOM 14175 CDl LEU D 417 5662C I 14738-73818 1003979 D

ATOM 14091 CA LYS D 407 49746 17349-77696 1003782 D ATOM 14176 CD2LEUD417 56431 12810 72261 1003979 D

ATOM 14092 CB LYS D 407 50091 17153-79171 10011223 D ATOM 14177 C LEU D 417 55594 12546-76252 1 004794 D

ATOM 14093 CG LYS D 407 51258 17984-79666 1009833 D ATOM 14178 O LEUD417 55675 11351 -76484 1 004304 D

ATOM 14094 CD LYS D 407 51382 17893-81184 1009833 D ATOM 14179 N THR D 418 56535 13418-76597 1 005487 D

ATOM 14095 CE LYS D 407 52653 18566-81689 1009833 D ATOM 14180 CA THR D 418 57747 13024-77299 1004793 D

ATOM 14096 NZ LYS D 407 53891 17870-81221 1009833 D ATOM 14181 CB THR D 418 57666 13370-78797 1008890 D

ATOM 14097 C LYS D 407 48579 16463-77345 1004713 D ATOM 14182 OGl THR D 418 5675( ) 12480-79442 1005731

ATOM 14098 O LYS D 407 48772 15276 77083 1004607 D D

ATOM 14099 N LYS D 408 47376 17030-77301 1005143 D ATOM 14183 CG2THRD418 59021 : 13236-79455 1005731

ATOM 14100 CA LYS D 408 46209 16220-76989 1005102 D

ATOM 14101 CB LYS D 408 45010 17096-76658 1005514 D ATOM 14184 C THRD418 58915 13778 -76703 1006312 D

ATOM 14102 CG LYS D 408 43814 16304-76179 1005394 D ATOM 14185 O THRD418 58992 14995 -76829 1 005659 D

ATOM 14103 CD LYS D 408 42768 17213 75592 1005394 D ATOM 14186 N ASPD419 59830 13064-76058 1 005114 D

ATOM 14104 CE LYS D 408 41595 16415-75051 1005394 D ATOM 14187 CA ASP D 419 60982 13727-75463 1005625 D

ATOM 14105 NZ LYS D 408 40600 17301-74359 1005394 D ATOM 14188 CB ASP D 419 61037 13449-73964 1009502 D

ATOM 14106 C LYS D 408 45957 15449 78269 1005115 D ATOM 14189 CG ASP D 419 61981 14382-73243 1007261 D

ATOM 14107 O LYS D 408 45567 16029-79275 1004972 D ATOM 14190 ODl ASPD419 61899 > 15606-73487 1007261 D

ATOM 14108 N ASP D 409 46198 14147-78256 1007103 D ATOM 14191 OD2ASPD419 62799 13902-72433 1007261 D

ATOM 14109 CA ASP D 409 46005 13398-79484 1007121 D ATOM 14192 C ASP D 419 62269 13272-76135 1 006034 D

ATOM 14110 CB ASP D 409 46568 11967-79361 1009496 D ATOM 14193 O ASPD419 62552 12080-76194 1 005523 D

ATOM 14111 CG ASP D 409 46180 11285-78074 1008778 D ATOM 14194 N LEU D 420 63046 14229-76641 1007408 D

ATOM 14112 ODl ASP D 409 44992 11341 -77712 1008778 D ATOM 14195 CA LEU D 420 64295 13934-77339 1007877 D

ATOM 14113 OD2 ASP D 409 47062 10678 -77433 1008778 D ATOM 14196 CB LEU D 420 64343 14745-78637 10012761 D

ATOM 14114 C ASP D 409 44564 13380-79977 1007112 D ATOM 14197 CG LEU D 420 65275 14261 -79744 1008656 D

ATOM 14115 O ASP D 409 43639 13705 -79234 1007485 D ATOM 14198 CDl LEU D 420 6478S ' 12916-80252 1008656 D

ATOM 14116 N LYS D 410 44415 13028-81257 1008572 D ATOM 14199 CD2 LEU D 420 6531C I 15275-80875 1008656 D

ATOM 14117 CA LYS D 410 43139 12936-81972 1009216 D ATOM 14200 C LEU D 420 65529 14249-76485 1 008134 D

ATOM 14118 CB LYS D 410 43187 11782 -82980 10016070 D ATOM 14201 O LEU D 420 65475 15100-75601 1 008066 D

ATOM 14119 CG LYS D 410 43237 10377-82357 10010015 D ATOM 14202 N VAL D 421 66640 13561 -76750 1 007023 D

ATOM 14120 CD LYS D 410 44595 10059-81721 10010015 D ATOM 14203 CA VAL D 421 67883 13779-76004 1006874 D

ATOM 14121 CE LYS D 410 44596 8674-81067 10010015 D ATOM 14204 CB VAL D 421 68013 12784-74842 10011121

ATOM 14122 NZ LYS D 410 45904 8339 80426 10010015 D U

ATOM 14123 C LYS D 410 41916 12753-81091 1009098 D ATOM 14205 CGl VAL D 421 6935: ' 12933 74165 1006664

ATOM 14124 O LYSD410 42007 12230-79988 1009051 D D

ATOM 14125 N ASP D 411 40766 13166 81607 1005058 D ATOM 14206 CG2VALD421 66931 1 13042 -73849 1006664

ATOM 14126 CA ASP D 411 39495 13076-80888 1004809

ATOM 14127 CB ASP D 411 38348 12756-81853 10015537 D ATOM 14207 C VAL D 421 69126 13659-76878 1 007100 D

ATOM 14128 CG ASP D 411 37736 14002-82464 10015537 D ATOM 14208 O VAL D 421 69241 12737-77680 1 006660 D

ATOM 14129 ODl ASP D 411 37364 14919-81699 10015537 D ATOM 14209 N ARG D 422 70053 14596 76709 1 008079 D

ATOM 14130 OD2ASPD411 37618 14061-83706 10015537 D ATOM 14210 CA ARG D 422 71301 14623 -77468 1008292 D

ATOM 14131 C ASPD411 39467 12084-79736 1004970 D ATOM 14211 CB ARG D 422 71860 16047-77466 10016918

ATOM 14132 O ASP D 411 39023 10947 -79896 1005388 D

ATOM 14133 N ALA D 412 39930 12548-78572 1007419 D ATOM 14212 CG ARG D 422 72128 16635-78835 10012977

ATOM 14134 CA ALA D 412 39983 11748-77354 1008721 D D

ATOM 14135 CB ALA D 412 40977 10627-77520 1004047 D ATOM 14213 CD ARG D 422 73423 16115-79427 10012977

ATOM 14136 C ALA D 412 40368 12615-76164 1008191 D D

ATOM 14137 O ALA D 412 40738 13779 -76320 1007696 D ATOM 14214 NE ARG D 422 73748 16803-80675 10012977

ATOM 14138 N ASN D 413 40284 12036 74975 1006646 IJ U

ATOM 14139 CA ASN D 413 40608 12759-73758 1005927 D ATOM 14215 CZ ARG D 422 74886 16648-81346 10012977

ATOM 14140 CB ASN D 413 39763 12248-72596 1006051 D D

ATOM 14141 CG ASN D 413 38276 12462-72815 1006051 D ATOM 14216 NHl ARG D 422 7582 1 15822-80890 10012977

ATOM 14142 ODl ASN D 413 37866 13511 -73326 1006051 D D

ATOM 14143 ND2ASND413 37452 11474-72410 1006051 D ATOM 14217 NH2 ARG D 422 75092 17324-82472 10012977

ATOM 14144 C ASN D 413 42063 12592 73389 1006385 D

ATOM 14145 O ASN D 413 42589 13308 -72542 1006354 D ATOM 14218 C ARG D 422 72308 13673-76819 1 008015 D

ATOM 14146 N THR D 414 42709 11639 -74039 1004063 D ATOM 14219 O ARG D 422 72926 14014-75812 1 007082 D

ATOM 14147 CA THR D 414 44097 11315-73776 1004367 D ATOM 14220 N THR D 423 72474 12483-77389 1 008795 D

ATOM 14148 CB THRD 414 44337 9857-74169 1009788 D ATOM 14221 CA THR D 423 73407 11499-76838 1009760 D

ATOM 14149 OGl THR D 414 45693 9523 -73907 1006837 D ATOM 14222 CB THR D 423 73209 10100-77481 10012621 D

ATOM 14150 CG2 THR D 414 44031 9630-75633 1006837 D ATOM 14223 OGl THR D 423 7185: I 9683-77310 1008200 D

ATOM 14151 C THR D 414 45132 12247 -74440 1004313 D ATOM 14224 CG2 THR D 423 74 Hf > 9063 76825 1008200 D

ATOM 14152 O THR D 414 44795 13019-75341 1004420 D ATOM 14225 C THR D 423 74861 11901-77041 1 009582 D

ATOM 14153 N TYRD415 46381 12192-73961 1004513 D ATOM 14226 O THR D 423 75596 11208-77737 1 009431 D

ATOM 14154 CA TYR D 415 47472 13024-74481 1004616 D ATOM 14227 N THR D 424 75281 13012-76442 10016473 D

ATOM 14155 CB TYRD415 47927 14040-73434 1007380 D ATOM 14228 CA THR D 424 76664 13458-76581 10016473

ATOM 14156 CG TYR D 415 46904 15090 -73074 1004074 D D

ATOM 14157 CDl TYR D 415 45749 14752 -72373 1004074 D ATOM 14229 CB THR D 424 76896 14811 -75878 10020084 D

ATOM 14158 CE ITYR D 415 44796 15713-72059 1004074 D ATOM 14230 OGl THR D 424 7599' t 15786-76416 10014806

ATOM 14159 CD2TYRD415 47083 16427-73451 1004074 D D

ATOM 14160 CE2TYRD415 46140 17393 -73140 1004074 D ATOM 14231 CG2 THR D 424 7832S I 15291 -76095 10014806

ATOM 14161 CZ TYR D 415 44996 17033 -72446 1004074 U

ATOM 14162 OH TYRD 415 44046 17984-72138 1004074 D ATOM 14232 C THR D 424 77580 12404-75966 1 0016473 D

ATOM 14163 C TYR D 415 48686 12184-74871 1005372 D ATOM 14233 O THR D 424 77159 11637-75100 1 0016473 D

ATOM 14164 O TYR D 415 48816 11030-74450 1004837 D ATOM 14234 N SER D 425 78830 12366-76416 1 0015856 D

ATOM 14165 N SER D 416 49580 12773-75663 1004540 D ATOM 14235 CA SER D 425 79789 11386-75920 : I 0015856 D

ATOM 14166 CA SER D 416 50795 12093 -76104 1004335 D ATOM 14236 CB SER D 425 80991 11313-76863 1 [ 0018662 D

ATOM 14167 CB SER D 416 50660 11646-77548 1008050 D ATOM 14237 OG SER D 425 81877 10283 76467 1008256 D

ATOM 14168 OG SER D 416 49795 10534-77632 1005688 D ATOM 14238 C SER D 425 80275 : 11654 -74496 1 0015856 D

ATOM 14169 C SER D 416 52004 12998-75957 1004954 D ATOM 14239 O SER D 425 81070 10885-73955 10015856 D

ATOM 14170 O SERD 416 51901 14226-76067 1004791 D ATOM 14240 N LYS D 426 79796 12739-73892 1 0015925 D

ATOM 14171 N LEU D 417 53158 12381 -75724 1003753 D ATOM 14241 CA LYS D 426 80190 13097-72531 10015925 D

ATOM 14172 CA LEU D 417 54396 13119-75508 1003643 D ATOM 14242 CB LYS D 426 79451 14358-72084 : I 0017608 D

ATOM 14173 CB LEU D 417 54711 13137-74014 1008168 D ATOM 14243 CG LYS D 426 79563 15520-73044 10012038 D

ATOM 14174 CG LEU D 417 56192 13282-73664 1003979 D ATOM 14244 CD LYS D 426 78657 16651 -72604 10012038 D 65251/C766

ATOM 14245 CE LYS D 426 78629 17766-73630 10012038 D ATOM 14330 NE2 HIS D 437 49000 8878-66753 1004271 D

ATOM 14246 NZ LYS D 426 77700 18852-73215 10012038 D ATOM 14331 C HIS D 437 52027 8536-63521 1004401 D

ATOM 14247 C LYS D 426 79877 11968-71551 I 0015925 D ATOM 14332 O HIS D 437 52464 7624 -62833 1004623 D

ATOM 14248 O LYS D 426 80655 11685-70639 10015925 D ATOM 14333 N ASP D 438 50788 8995-63384 1004645 D

ATOM 14249 N MET D 427 78729 11329 -71750 10016882 D ATOM 14334 CA ASP D 438 49878 8430-62388 1004836 D

ATOM 14250 CA MET D 427 78283 10238-70890 10016882 D ATOM 14335 CB ASP D 438 48522 9121 -62462 1009914 D

ATOM 14251 CB MET D 427 76844 9852 -71242 10012065 D ATOM 14336 CG ASP D 438 48489 10406-61660 1007010 D

ATOM 14252 CG MET D 427 76620 9570 72717 10012065 D ATOM 14337 ODl ASP D 438 49576 10968 -61398 1007010 D

ATOM 14253 SD MET D 427 74900 9190-73074 10012065 D ATOM 14338 OD2ASPD438 47380 10856-61299 1007010 D

ATOM 14254 CE MET D 427 74164 10835 -73056 10012065 D ATOM 14339 C ASP D 438 49735 6925 -62543 1004970 D

ATOM 14255 C MET D 427 79169 9004-70968 10016882 D ATOM 14340 O ASP D 438 49809 6191-61560 1005326 D

ATOM 14256 O MET D 427 80312 9073-71420 10016882 D ATOM 14341 N THR D 439 49515 6461-63767 1007503 D

ATOM 14257 N SER D 428 78630 7874-70521 10010078 D ATOM 14342 CA THR D 439 49440 5029 -64021 1007238 D

ATOM 14258 CA SER D 428 79374 6622-70534 10010243 D ATOM 14343 CB THR D 439 48773 4746 -65376 1006132 D

ATOM 14259 CB SER D 428 80523 6690-69527 10011517 D ATOM 14344 OGl THR D 439 49564 5299 66433 1004713 D

ATOM 14260 OG SER D 428 80028 6847 -68209 10011188 D ATOM 14345 CG2THRD439 47401 5392-65423 1004713 D

ATOM 14261 C SER D 428 78508 5404-70219 1009838 D ATOM 14346 C THR D 439 50930 4692-64063 1007815 D

ATOM 14262 O SER D 428 79005 4427 -69661 1009826 D ATOM 14347 O THR D 439 51720 5516-64512 1007849 D

ATOM 14263 N SER D 429 77225 5455-70574 10013090 D ATOM 14348 N LEU D 440 51332 3515-63599 1005619 D

ATOM 14264 CA SER D 429 76318 4336-70314 10012957 D ATOM 14349 CA LEU D 440 52764 3170-63551 1005821 D

ATOM 14265 CB SER D 429 75883 4328-68849 10013449 D ATOM 14350 CB LEU D 440 53357 2926-64968 1007212 D

ATOM 14266 OG SER D 429 76981 4126-67983 10013449 D ATOM 14351 CG LEU D 440 53566 3773-66253 1005212 D

ATOM 14267 C SER D 429 75068 4360-71180 10012795 D ATOM 14352 CDl LEU D 440 52238 4047 -66886 1005212 D

ATOM 14268 O SER D 429 74299 3401 -71190 10011665 D ATOM 14353 CD2 LEU D 440 54341 5052-66004 1005212 D

ATOM 14269 N GLN D 430 74867 5448-71912 1008061 D ATOM 14354 C LEU D 440 53605 4223-62815 1006816 D

ATOM 14270 CA GLN D 430 73681 5594-72750 1008061 D ATOM 14355 O LEU D 440 54312 4993-63449 1006638 D

ATOM 14271 CB GLN D 430 73526 4428-73718 10017527 D ATOM 14356 N GLU D 441 53532 4244-61481 1005645 D

ATOM 14272 CG GLN D 430 72335 4613-74629 10010426 D ATOM 14357 CA GLU D 441 54265 5215-60652 1005645 D

ATOM 14273 CD GLN D 430 72126 3455-75568 10010426 D ATOM 14358 CB GLU D 441 54520 4637-59259 10020028 D

ATOM 14274 OEl GLN D 430 71765 2355-75147 10010426 D ATOM 14359 CG GLU D 441 53254 4401 -58456 10012364 D

ATOM 14275 NE2GLND430 72355 3694-76857 10010426 D ATOM 14360 CD GLU D 441 53541 3977-57026 10012364 D

ATOM 14276 C GLN D 430 72470 5651-71828 1008061 D ATOM 14361 OEI GLU D 441 54236 2953-56835 10012364

ATOM 14277 O GLN D 430 72105 4659-71191 1008061 D D

ATOM 14278 N PRO D 431 71813 6816-71765 1005381 D ATOM 1144336622 OOEE22GGLLUUDD444411 53071 4669 56092 10012364

ATOM 14279 CD PRO D 431 71902 7959 -72686 1004084 D D

ATOM 14280 CA PRO D 431 70655 6955 -70896 1005380 D ATOM 14363 C GLU D 441 55584 5707 -61252 1005645 D

ATOM 14281 CB PRO D 431 70258 8410-71096 10013980 D ATOM 14364 O GLU D 441 55870 6904-61234 1005645 D

ATOM 14282 CG PRO D 431 70551 8616-72526 10011036 D ATOM 14365 N ALA D 442 56383 4789-61784 1005236 D

ATOM 14283 C PRO D 431 69527 5998-71216 1005042 D ATOM 14366 CA ALA D 442 57655 5145 -62408 1005058 D

ATOM 14284 O PRO D 431 69419 5464-72322 1005030 D ATOM 14367 CB ALA D 442 58621 5674-61362 1003197 D

ATOM 14285 N VAL D 432 68700 5789 -70202 1005635 D ATOM 14368 C ALA D 442 58250 3922-63090 1004657 D

ATOM 14286 CA VAL D 432 67521 4956-70288 1005873 D ATOM 14369 O ALA D 442 58717 3007-62418 1004398 D

ATOM 14287 CB VAL D 432 67599 3808-69273 1007391 D ATOM 14370 N GLN D 443 58228 3899 -64420 1004150 D

ATOM 14288 CGl VAL D 432 67664 4351-67874 1004599 D ATOM 14371 CA GLN D 443 58775 2777-65180 1004478 D

ATOM 14289 CG2 VAL D 432 66426 2923 -69422 1004599 D ATOM 14372 CB GLN D 443 57723 2195-66120 1008254 D

ATOM 14290 C VAL D 432 66407 5948 -69929 1005673 D ATOM 14373 CG GLN D 443 56919 1082-65504 1006577 D

ATOM 14291 O VAL D 432 66635 6903-69186 1004709 D ATOM 14374 CD GLN D 443 56245 0224 -66556 1006577 D

ATOM 14292 N CYS D 433 65215 5759-70475 1006931 D ATOM 14375 OEl GLN D 443 56890 -0231 -67501 1006577 D

ATOM 14293 CA CYS D 433 64130 6690 70190 1006519 D ATOM 14376 NE2 GLN D 443 54947 -o 009 -66400 1006577 D

ATOM 14294 C CYS D 433 63256 6251-69019 1006283 D ATOM 14377 C GLN D 443 60004 3165-65986 1004695 D

ATOM 14295 O CYS D 433 62707 5147-69030 1006357 D ATOM 14378 O GLN D 443 60148 4321-66419 1004801 D

ATOM 14296 CB CYS D 433 63265 6877 71442 10014192 D ATOM 14379 N VAL D 444 60892 2191 -66183 1004587 D

ATOM 14297 SG CYS D 433 61958 8137-71276 1008903 D ATOM 14380 CA VAL D 444 62111 2416-66952 1004302 D

ATOM 14298 N VAL D 434 63150 7105-67998 1004800 D ATOM 14381 CB VAL D 444 63309 1811 -66237 1005291 D

ATOM 14299 CA VAL D 434 62298 6817-66841 1004399 D ATOM 14382 CGl VAL D 444 64597 2382-66806 1004521 D

ATOM 14300 CB VAL D 434 62996 7103 -65522 1005564 D ATOM 14383 CG2 VAL D 444 63210 2104 64754 1004521 D

ATOM 14301 CGl VAL D 434 62135 6612-64383 1003742 D ATOM 14384 C VAL D 444 61981 1800-68344 1004684 D

ATOM 14302 CG2 VAL D 434 64332 6422-65492 1003742 D ATOM 14385 O VAL D 444 61411 0722-68490 1004910 D

ATOM 14303 C VAL D 434 61062 7713-66929 1005439 D ATOM 14386 N TYR D 445 62481 2498-69364 1004170 D

ATOM 14304 O VAL D 434 61164 8937-66888 1004545 D ATOM 14387 CA TYR D 445 62412 2021 -70749 1004077 D

ATOM 14305 N VAL D 435 59894 7093 -67040 1004124 D ATOM 14388 CB TYR D 445 61324 2774-71511 1007246 D

ATOM 14306 CA VAL D 435 58643 7826-67186 1003298 D ATOM 14389 CG TYR D 445 59959 2616-70889 1004488 D

ATOM 14307 CB VAL D 435 57780 7188-68309 1005368 D ATOM 14390 CDl TYR D 445 59500 3501 -69905 1004488 D

ATOM 14308 CGl VAL D 435 56381 7772-68311 1003301 D ATOM 14391 CEl TYR D 445 58242 3349 -69320 1004488 D

ATOM 14309 CG2VALD435 58447 7409 -69654 1003301 D ATOM 14392 CD2 TYR D 445 59128 1577-71267 1004488 D

ATOM 14310 C VAL D 435 57813 7884-65913 1004090 D ATOM 14393 CE2 TYR D 445 57869 1408 -70690 1004488 D

ATOM 14311 O VAL D 435 57443 6848 -65367 1004149 D ATOM 14394 CZ TYR D 445 57428 2294 -69722 1004488 D

ATOM 14312 N PHE D 436 57519 9102-65453 1004014 D ATOM 14395 OH TYR D 445 56166 2116-69189 1004488 D

ATOM 14313 CA PHE D 436 56707 9303 -64260 1003634 D ATOM 14396 C TYR D 445 63762 2204 -71436 1004223 D

ATOM 14314 CB PHE D 436 57328 10357-63359 1007175 D ATOM 14397 O TYR D 445 64407 3244-71293 1004509 D

ATOM 14315 CG PHE D 436 58668 9972 62821 1004652 D ATOM 14398 N THR D 446 64175 1204-72207 1004058 D

ATOM 14316 CDl PHE D 436 59830 10231-63551 1004652 D ATOM 14399 CA THR D 446 65478 1243 -72857 1004756 D

ATOM 14317 CD2 PHE D 436 58777 9327-61581 1004652 D ATOM 14400 CB THR D 446 66325 0075 -72354 1005492 D

ATOM 14318 CEl PHE D 436 61085 9856 -63055 1004652 D ATOM 14401 OGl THR D 446 65635 -1141 -72632 1004307 D

ATOM 14319 CE2 PHE D 436 60026 8945-61071 1004652 D ATOM 14402 CG2 THR D 446 66529 0157 -70864 1004307 D

ATOM 14320 CZ PHE D 436 61181 9211-61808 1004652 D ATOM 14403 C THR D 446 65539 1220 -74383 1005736 D

ATOM 14321 C PHE D 436 55288 9730-64636 1004417 D ATOM 14404 O THR D 446 64604 1606 -75072 1006103 D

ATOM 14322 O PHE D 436 55082 10775 -65245 1004355 D ATOM 14405 N CYS D 447 66701 0763-74856 1008341 D

ATOM 14323 N HIS D 437 54310 8909-64274 1003863 D ATOM 14406 CA CYS D 447 67121 0584 -76255 1008439 D

ATOM 14324 CA HIS D 437 52914 9191-64574 1003970 D ATOM 14407 C CYS D 447 67270 1775-77196 1008442 D

ATOM 14325 CB HIS D 437 52563 8644 -65942 1006634 D ATOM 14408 O CYS D 447 66488 2714-77183 1008128 D

ATOM 14326 CG HIS D 437 51154 8912-66339 1004271 D ATOM 14409 CB CYS D 447 66289 -0509 -76946 10010043 D

ATOM 14327 CD2 HIS D 437 50055 8122-66306 1004271 D ATOM 14410 SG CYS D 447 64503 -0237 -77065 1008596 D

ATOM 14328 NDl HIS D 437 50735 10139 66810 1004271 D ATOM 14411 N SER D 448 68320 1704 -78011 10018309 D

ATOM 14329 CEl HIS D 437 49437 10090-67052 1004271 D ATOM 14412 CA SER D 448 68647 2729-78992 10018309 D 65251/C766

ATOM 14413 CB SER D 448 69947 3436-78610 10020084 D ATOM 14498 O VALE 8 70397 -0530 -23839 1004085 E

ATOM 14414 OG SER D 448 69834 4048 -77338 10020084 D ATOM 14499 N ALAE 9 68261 -0097-24419 1003699 E

ATOM 14415 C SER D 448 68800 2076-80359 10018309 D ATOM 14500 CA ALAE 9 67807 -1413 -24029 1004323 E

ATOM 14416 O SER D 448 68227 1015-80603 10018309 D ATOM 14501 CB ALAE 9 67830 -1550-22518 1003794 E

ATOM 14417 N GLU D 449 69592 2692 81235 10015134 D ATOM 14502 C ALAE 9 66414 -1687-24535 1004421 E

ATOM 14418 CA GLU D 449 69779 2180-82590 10015134 D ATOM 14503 O ALAE 9 65530 -0834-24458 1004219 E

ATOM 14419 CB GLU D 449 70153 0691-82575 10011321 D ATOM 14504 N HIS E 10 66229 -2887-25061 1003955 E

ATOM 14420 CG GLU D 449 71613 0412-82296 10011321 D ATOM 14505 CA HISE 10 64939 -3322-25542 1004042 E

ATOM 14421 CD GLU D 449 72129 1216-81 127 10011321 D ATOM 14506 CB HISE 10 64850 -3254 -27065 1003506 E

ATOM 14422 OE 1 GLU D 449 71519 1 140-80039 10011321 D ATOM 14507 CG HISE 10 63511 -3654 -27597 1003655 E

ATOM 14423 OE2 GLU D 449 73143 1925-81300 10011321 D ATOM 14508 CD2 HIS E 10 63067 -4829 -28104 I 003428 E

ATOM 14424 C GLU D 449 68442 2361 -83289 10015134 D ATOM 14509 NDl HIS E 10 62424 -2809 -27586 1003669 E

ATOM 14425 O GLU D 449 68371 2791 -84440 10015134 D ATOM 14510 CE 1 HISE 10 61367 -3444 -28066 1003704 E

ATOM 14426 N GLY D 450 67384 2038 -82557 1006888 D ATOM 14511 NE2 HIS E 10 61730 -4671-28387 1003452 E

ATOM 14427 CA GLY D 450 66031 2142-83057 1006888 D ATOM 14512 C HISE 10 64856 -4770 25079 1003863 E

ATOM 14428 C GLY D 450 65268 1021 -82396 1006888 D ATOM 14513 O HlSE 10 65418 -5671 25704 1003679 E

ATOM 14429 O GLY D 450 64141 0705-82772 1006888 D ATOM 14514 N VALE 11 64188 -4985 -23958 1004305 E

ATOM 14430 N CYS D 451 65903 0421 -81395 10017293 D ATOM 14515 CA VALE 11 64050 -6324 -23425 1004563 E

ATOM 14431 CA CYS D 451 65322 -0694 -80666 10017293 D ATOM 14516 CB VALE 11 64295 -6353 -21914 1004238 E

ATOM 14432 CB CYS D 451 64024 -0284 -80005 10014359 D ATOM 14517 CGl VALE ; Ii 65718 -5888-21640 1003844 E

ATOM 14433 SG CYS D 451 64291 0924-78697 10014359 D ATOM 14518 CG2 VAL £ ; ii 63285 -5465-21187 1004436 E

ATOM 14434 C CYS D 451 65045 -1825-81621 10017293 D ATOM 14519 C VALE 11 62669 -6853 -23744 1004424 E

ATOM 14435 O CYS D 451 63875 -2257 81679 10017293 D ATOM 14520 O VALE 11 61702 -6088-23921 1004125 E

ATOM 14436 OXT CYS D 451 66002 -2254-82297 10011596 D ATOM 14521 N VALE 12 62579 -8171 -23820 1005728 E

ATOM 14437 CB ARGE 1 78700 -3181-35806 10012479 E ATOM 14522 CA VALE 12 61330 -8801 -24182 1005545 E

ATOM 14438 CG ARGE 1 77750 -4084 -35003 10012479 E ATOM 14523 CB VALE 12 61497 -9454 -25558 1006215 E

ATOM 14439 CD ARGE 1 78411 -5350-34451 10012479 E ATOM 14524 CGl VALI • 12 62353 -10695 -25440 1005595 E

ATOM 14440 NE ARGE 1 78937 -5185-33092 10012479 E ATOM 14525 CG2 VAL E L 12 60155 -9747 -26158 1006562 E

ATOM 14441 CZ ARGE 1 78190 -4951 -32012 10012479 E ATOM 14526 C VALE 12 60938 -9823 -23120 1005341 E

ATOM 14442 NHl ARG E 1 76871 -4851 -32120 10012479 E ATOM 14527 O VALE 12 61784 -10263 -22329 1005325 E

ATOM 14443 NH2ARGE 1 78762 -4817-30820 10012479 E ATOM 14528 N ALAE 13 59658 -10187 -23095 1005398 E

ATOM 14444 C ARGE 1 79441 -1892 -33768 10020084 E ATOM 14529 CA ALAE 13 59139-11132-22105 1005365 E

ATOM 14445 O ARGE 1 79032 -2526 -32797 10020084 E ATOM 14530 CB ALAE 13 57618-11056 -22052 1002781 E

ATOM 14446 N ARGE 1 80861 -3712-34714 10020084 E ATOM 14531 C ALAE 13 59562-12564 22344 1005763 E

ATOM 14447 CA ARGE 1 79905 -2615 -35038 10020084 E ATOM 14532 O ALAE 13 59575 -13025 -23476 1005514 E

ATOM 14448 N THRE 2 79513 -0564 -33778 10019258 E ATOM 14533 N ASNE 14 59897 -13258 -21260 1007112 E

ATOM 14449 CA THRE 2 79109 0242-32625 10019258 E ATOM 14534 CA ASNE 14 60317-14653-21307 1007224 E

ATOM 14450 CB THRE 2 79678 1687-32713 10014302 E ATOM 14535 CB ASNE 14 61129 -14979 -20060 1009093 E

ATOM 14451 OGl THRE 2 81 105 1642 -32839 10014176 E ATOM 14536 CG ASNE 14 61601-16413-20033 1009292 E

ATOM 14452 CG2THRE 2 79308 2489-31467 10014491 E ATOM 14537 ODl ASN E ! 14 62207-16855-19059 1009250 E

ATOM 14453 C THRE 2 77591 0363-32533 10019258 E ATOM 14538 ND2 ASN E ; 14 61330-17149-21 106 1009504 E

ATOM 14454 O THRE 2 76976 1020 -33374 10019258 E ATOM 14539 C ASNE 14 59083-15553-21370 1007512 E

ATOM 14455 N PROE 3 76961 -0276-31526 10020084 E ATOM 14540 O ASNE 14 58290 -15592 -20428 1007564 E

ATOM 14456 CD PROE 3 77422 -1227 -30496 1008028 E ATOM 14541 N PROE 15 58912-16301 -22474 1007424 E

ATOM 14457 CA PROE 3 75506 -0117 -31478 10020084 E ATOM 14542 CD PROE 15 59751 -16379-23682 1004818 E

ATOM 14458 CB PROE 3 75146 -0671 -30099 1007852 E ATOM 14543 CA PROE 15 57742-17180-22599 1007784 E

ATOM 14459 CG PROE 3 76103 -1824-29976 1007839 E ATOM 14544 CB PROE 15 57704-17515-24100 1005252 E

ATOM 14460 C PROE 3 75184 1368-31646 10020084 E ATOM 14545 CG PROE 15 58717-16560-24751 1005079 E

ATOM 14461 O PROE 3 74183 1723 -32270 10020084 E ATOM 14546 C PROE 15 57861 -18438-21740 1007905 E

ATOM 14462 N SERE 4 76062 2220-31 105 10014245 E ATOM 14547 O PROE 15 56865-19084-21422 1008108 E

ATOM 14463 CA SERE 4 75935 3677-31209 10013902 E ATOM 14548 N GLNE 16 59089-18773-21367 1009558 E

ATOM 14464 CB SERE 4 74466 4122 31 144 10014569 E ATOM 14549 CA GLNE 16 59351-19958-20563 1009453 E

ATOM 14465 OG SERE 4 74011 4216-29806 10014764 E ATOM 14550 CB GLNE 16 60817-20375-20740 10014200 E

ATOM 14466 C SERE 4 76709 4453-30150 10013936 E ATOM 14551 CG GLNE 16 61133-21821 -20377 10014493 E

ATOM 14467 O SERE 4 77170 5560-30428 10013951 E ATOM 14552 CD GLNE 16 60344-22821 -21208 10014672 E

ATOM 14468 N ASPE 5 76846 3873 -28954 1006179 E ATOM 14553 OEl GLN E i 16 60202 -22665 22423 10014884 E

ATOM 14469 CA ASPE 5 77528 4514 -27822 1006190 E ATOM 14554 NE2 GLN E ^■ 16 59837 -23863 -20556 10014537 E

ATOM 14470 CB ASPE 5 78351 5718-28305 10015943 E ATOM 14555 C GLNE 16 59040-19743-19075 1009120 E

ATOM 14471 CG ASPE 5 79030 6463-27180 10015943 E ATOM 14556 O GLNE 16 59255-20639-18255 1009177 E

ATOM 14472 ODlASPE 5 79576 7555-27444 1 0015943 E ATOM 14557 N ALAE 17 58534-18560-18728 1009779 E

ATOM 14473 0D2ASPE 5 79027 5963-26038 10015799 E ATOM 14558 CA ALAE 17 58203-18246-17334 10010155 E

ATOM 14474 C ASPE 5 76473 4972 -26792 1005940 E ATOM 14559 CB ALAE 17 59013-17049-16850 1005108 E

ATOM 14475 O ASPE 5 76771 5137-25607 1006291 E ATOM 14560 C ALAE 17 56718-17961 -17179 10010605 E

ATOM 14476 N LYSE 6 75238 5169-27254 1005501 E ATOM 14561 O ALAE 17 56318-16855-16818 10010769 E

ATOM 14477 CA LYSE 6 74120 5599-26403 1005139 E ATOM 14562 N GLUE 18 55909-18975-17451 1008499 E

ATOM 14478 CB LYSE 6 72931 6057-27253 1006014 E ATOM 14563 CA GLUE 18 54463-18860-17357 1008699 E

ATOM 14479 CG LYSE 6 73052 7338 -28028 1006655 E ATOM 14564 CB GLUE 18 53818-20239-17506 10012907 E

ATOM 14480 CD LYSE 6 71809 7472-28905 1007016 E ATOM 14565 CG GLUE 18 54233-21233-16432 10012907 E

ATOM 14481 CE LYSE 6 71729 8815-29582 1007343 E ATOM 14566 CD GLUE 18 53469 -22542 -16520 10012907 E

ATOM 14482 NZ LYSE 6 71583 9888 -28566 1007462 E ATOM 14567 OEl GLU E ; 18 52226-22514-16387 10012907 E

ATOM 14483 C LYSE 6 73571 4482-25518 1004672 E ATOM 14568 OE2 GLU E ; is 54110-23598-16721 10012907 E

ATOM 14484 O LYSE 6 73328 3373 -25995 1005060 E ATOM 14569 C GLUE 18 54009 -18235 -16047 1008665 E

ATOM 14485 N PROE 7 73362 4752-24221 1004354 E ATOM 14570 O GLUE 18 54661 -18386-15014 1008626 E

ATOM 14486 CD PROE 7 73772 5875 -23369 1004485 E ATOM 14571 N GLYE 19 52885-17525-16114 1009426 E

ATOM 14487 CA PROE 7 72812 3658-23413 1004158 E ATOM 14572 CA GLYE 19 52319 16893-14940 1009175 E

ATOM 14488 CB PROE 7 72731 4251 -21997 1004685 E ATOM 14573 C GLYE 19 52970-15606-14485 1009025 E

ATOM 14489 CG PROE 7 72816 5725-22205 1004572 E ATOM 14574 O GLYE 19 52433-14933-13612 1009026 E

ATOM 14490 C PROE 7 71450 3337 -23999 1003964 E ATOM 14575 N GLNE 20 54113-15247-15058 1009390 E

ATOM 14491 O PROE 7 70674 4239-24311 1004065 E ATOM 14576 CA GLNE 20 54793-14023-14648 1008947 E

ATOM 14492 N VALE 8 71 171 2052-24173 1003795 E ATOM 14577 CB GLNE 20 55892-14356-13638 10010179 E

ATOM 14493 CA VALE 8 69911 1629-24759 1003911 E ATOM 14578 CG GLNE 20 56856-15406-14126 10010277 E

ATOM 14494 CB VALE 8 70019 1619-26301 1004288 E ATOM 14579 CD GLNE 20 57883-15775-13081 10010253 E

ATOM 14495 CGlVALE 8 71 154 0696-26728 1004346 E ATOM 14580 OEl GLN E 57534-16232-11996 10010218 E

ATOM 14496 CG2VALE 8 68702 1 171-26930 1004558 E ATOM 14581 NE2 GLN E ; 20 59160-15578-13401 10010198 E

ATOM 14497 C VALE 8 69539 0235 -24295 1004161 E ATOM 14582 C GLNE 20 55382-13252-15825 1008421 E 65251/C766

ATOM 145S3 O GLNE 20 55416-13748-16947 1008292 E ATOM 14668 CB ALA E 30 66468 -8453 -27047 1003375 E ATOM 14584 N LEUE 21 55839-12032-15559 1005838 E ATOM 14669 C ALAE 30 67995 -6672 -27920 1003041 E

ATOM 14585 CA LEUE 21 56420-11185-16586 1005484 E ATOM 14670 O ALAE 30 68992 -6866 -28628 1003456 E

ATOM 14586 CB LEU E 21 55674 -9851 -16646 1006009 E ATOM 14671 N LEUE 31 67963 -5785 -26924 1004338 E

ATOM 14587 CG LEUE 21 56192 -8789-17617 1005887 E ATOM 14672 CA LEU E 31 69125 4971 -26608 1004285 E ATOM 14588 CDl LEUE 21 56422 -9384-18993 1005617 E ATOM 14673 CB LEU E 31 69038 -3631 -27320 1003841 E ATOM 14589 CD2 LEU E 21 55177 -7660 -17696 1006091 E ATOM 14674 CG LEU E 31 69210 -3545 -28826 1004129 E

ATOM 14590 C LEUE 21 57891 10942 16298 1005345 E ATOM 14675 CDl LEUE 31 68750 -2179-29313 1003891 E

ATOM 14591 O LEUE 21 58247 -9998-15604 1004877 E ATOM 14676 CD2LEUE 31 70657 -3783 -29172 1004076 E

ATOM 14592 N GLNE 22 58745-11796-16840 1005226 E ATOM 14677 C LEUE 31 69292 -4695 -25130 1004211 E ATOM 14593 CA GLNE 22 60184-11684-16634 1005686 E ATOM 14678 O LEUE 31 68309 -4621 -24392 1004292 E

ATOM 14594 CB GLN E 22 60724 -13055 -16239 1008201 E ATOM 14679 N LEU E 32 70553 -4537 24726 1004042 E ATOM 14595 CG GLN E 22 62228-13162-16153 1008878 E ATOM 14680 CA LEU E 32 70945 -4220-23358 1004021 E ATOM 14596 CD GLN E 22 62685 -14606 -16056 1009500 E ATOM 14681 CB LEU E 32 70829 -5434 -22443 1004634 E ATOM 14597 OEl GLN E 22 63882-14897-16112 10010023 E ATOM 14682 CG LEUE 32 71127 5069 20983 1004492 E ATOM 14598 NE2 GLN E 22 61730-15520-15911 1009576 E ATOM 14683 CDl LEU E 32 70044 -4124 -20472 1004390 E

ATOM 14599 C GLNE 22 60864-11185-17910 1005425 E ATOM 14684 CD2 LEU E 32 71179 -6331-20114 1004524 E

ATOM 14600 0 GLN E 22 60692-11766-18975 1005320 E ATOM 14685 C LEU E 32 72396 -3793 -23467 1003985 E

ATOM 14601 N TRP E 23 61643-10114-17805 1006066 E ATOM 14686 O LEU E 32 73302 -4581 -23209 1004572 E

ATOM 14602 CA TRPE 23 62313 -9544-18974 1005454 E ATOM 14687 N ALA E 33 72619 -2538 -23844 1004534 E

ATOM 14603 CB TRP E 23 62521 -8033 -18797 1005358 E ATOM 14688 CA ALA E 33 73979 -2068 -24033 1004586 E ATOM 14604 CG TRP E 23 61284 -7261 -18492 1005410 E ATOM 14689 CB ALA E 33 74315 -2114 -25505 1008759 E

ATOM 14605 CD2 TRP E 23 60183 -7010-19377 1005221 E ATOM 14690 C ALA E 33 74356 -0706 -23490 1004765 E

ATOM 14606 CE2 TRP E 23 59245 -6229 18662 1005383 E ATOM 14691 O ALAE 33 73529 0055 -23004 1005183 E

ATOM 14607 CE3 TRP E 23 59896 -7368 -20701 1005190 E ATOM 14692 N ASN E 34 75649 -0429 -23597 1005143 E ATOM 14608 CDl TRPE 23 60980 -6645-17318 1005357 E ATOM 14693 CA ASN E 34 76247 0820 -23174 1004862 E ATOM 14609 NEl TRP E 23 59758 6020 17409 1005266 E ATOM 14694 CB ASN E 34 75871 1902-24162 1006079 E

ATOM 14610 CZ2 TRP E 23 58040 -5798 -19226 1005589 E ATOM 14695 CG ASN E 34 76342 1577 -25559 1006471 E

ATOM 14611 CZ3 TRP E 23 58695 -6940 -21266 1005634 E ATOM 14696 ODl ASN E 34 77511 1261 -25767 1006719 E ATOM 14612 CH2 TRP E 23 57782 -6161 -20525 1005415 E ATOM 14697 ND2 ASN E 34 75439 1652-26525 1006012 E

ATOM 14613 C TRP E 23 63670-10155-19274 1005504 E ATOM 14698 C ASN E 34 75950 1276 -21769 1004937 E

ATOM 14614 0 TRP E 23 64463-10382-18362 1005632 E ATOM 14699 O ASN E 34 75716 2450-21534 1005191 E ATOM 14615 N LEU E 24 63938-10416-20553 1004413 E ATOM 14700 N GLY E 35 75950 0351 -20824 1004424 E

ATOM 14616 CA LEU E 24 65241-10940-20953 1004182 E ATOM 14701 CA GLY E 35 75725 0765 19460 1003883 E

ATOM 14617 CB LEU E 24 65192 -12404 -21393 1008057 E ATOM 14702 C GLY E 35 74437 0393-18776 1003918 E ATOM 14618 CG LEUE 24 64006-13294-21065 1008130 E ATOM 14703 O GLY E 35 74438 0139-17577 1004067 E ATOM 14619 CDl LEU E 24 62843 -12882 -21934 1008292 E ATOM 14704 N VAL E 36 73327 0358-19486 1004082 E ATOM 14620 CD2 LEU E 24 64365-14739-21335 1007641 E ATOM 14705 CA VAL E 36 72109 0025-18775 1004215 E

ATOM 14621 C LEU E 24 65767-10118-22105 1004868 E ATOM 14706 CB VALE 36 70824 0376-19609 1003618 E

ATOM 14622 O LEU E 24 65008 -9453 -22814 1004566 E ATOM 14707 CGlVALE 36 71208 0775-21010 1003421 E

ATOM 14623 N ASNE 25 67079-10176-22278 1003902 E ATOM 14708 CG2 VAL E 36 69839 -0767-19610 1003658 E ATOM 14624 CA ASN E 25 67748 -9461 -23341 1004046 E ATOM 14709 C VALE 36 72159 -1433-18355 1004630 E ATOM 14625 CB ASN E 25 68725 -8466 -22735 1005407 E ATOM 14710 O VAL E 36 72648 -2299-19091 1004726 E ATOM 14626 CG ASN E 25 69946 9153 -22142 1005564 E ATOM 14711 N GLU E 37 71682 -1695 -17146 1004375 E ATOM 14627 ODl ASN E 25 71070 -8982 -22619 1005963 E ATOM 14712 CA GLU E 37 71686 -3041 -16613 1004635 E ATOM 14628 ND2 ASN E 25 69724 9952-21109 1005204 E ATOM 14713 CB GLU E 37 72482 -3065-15308 1005826 E

ATOM 14629 C ASN E 25 68528-10442-24227 1004099 E ATOM 14714 CG GLU E 37 73709 -2181 -15346 1006529 E

ATOM 14630 0 ASN E 25 69111 -10045-25232 1004335 E ATOM 14715 CD GLU E 37 74289 -1904 -13967 1006826 E

ATOM 14631 N ARG E 26 68548 11715-23847 1005310 E ATOM 14716 OEl GLU E 37 73518 -1899-12973 1007169 E ATOM 14632 CA ARG E 26 69291-12720 -24602 1005438 E ATOM 14717 OE2 GLU E 37 75515 -1669 -13882 1006882 E ATOM 14633 CB ARG E 26 69776-13823 -23652 1007950 E ATOM 14718 C GLU E 37 70266 -3524-16358 1004524 E ATOM 14634 CG ARG E 26 68677 -14471 -22830 1008041 E ATOM 14719 O GLU E 37 69346 -2733-16168 1004770 E ATOM 14635 CD ARG E 26 69187 -15739 -22174 1008447 E ATOM 14720 N LEU E 38 70094 -4837 -16379 1005776 E ATOM 14636 NE ARGE 26 68156-16405-21388 1008561 E ATOM 14721 CA LEUE 38 68803 -5427-16110 1005980 E ATOM 14637 CZ ARG E 26 67837 -16060 -20149 1008617 E ATOM 14722 CB LEUE 38 68458 -6439-17192 1004650 E ATOM 14638 NHl ARGE 26 68480-15057-19561 1008665 E ATOM 14723 CG LEU E 38 67080 -7080-17073 1004441 E ATOM 14639 NH2 ARG E 26 66873-16714 -19503 1008520 E ATOM 14724 CDl LEUE 38 66036 -6006-16835 1004279 E

ATOM 14640 C ARG E 26 68512-13348 -25760 1005244 E ATOM 14725 CD2 LEU E 38 66768 -7892-18343 1004128 E

ATOM 14641 O ARG E 26 68524-14567-25929 1005215 E ATOM 14726 C LEU E 38 69036 -6099-14770 1006007 E

ATOM 14642 N ARG E 27 67849-12520-26564 1004551 E ATOM 14727 O LEUE 38 69678 -7144 -14692 1005368 E ATOM 14643 CA ARG E 27 67069-13029 -27679 1004644 E ATOM 14728 N ARG E 39 68535 -5473-13712 1005658 E ATOM 14644 CB ARG E 27 65579-12975 -27356 1004285 E ATOM 14729 CA ARG E 39 68728 -5961-12354 1006311 E ATOM 14645 CG ARGE 27 65179-13924-26259 1004427 E ATOM 14730 CB ARGE 39 69598 -4951 -11613 1005301 E ATOM 14646 CD ARG E 27 65686 -15321 -26563 1004664 E ATOM 14731 CG ARG E 39 70110 -5395-10281 1006071 E ATOM 14647 NE ARG E 27 65435 -16272 -25482 1005003 E ATOM 14732 CD ARG E 39 71166 -4425 -9791 1006932 E ATOM 14648 CZ ARG E 27 64221 -16636 -25088 1005364 E ATOM 14733 NE ARGE 39 71898 -4964 -8649 1007585 E ATOM 14649 NHl ARG E 27 64082 -17516 -24097 1005451 E ATOM 14734 CZ ARG E 39 73037 ^ 454 -8181 1007665 E

ATOM 14650 NH2 ARG E 27 63145 16113 -25690 1005187 E ATOM 14735 NHl ARG E 39 73577 -3383 -8760 1007513 E

ATOM 14651 C ARG E 27 67329-12311-28981 1004690 E ATOM 14736 NH2 ARG E 39 73647 -5016 -7140 1007895 E

ATOM 14652 O ARG E 27 68072 -11325 -29028 1004704 E ATOM 14737 C ARG E 39 67395 -6145-11642 1006516 E

ATOM 14653 N ALAE 28 66692-12838-30026 1008529 E ATOM 14738 O ARG E 39 66551 -5253-11657 1006839 E ATOM 14654 CA ALA E 28 66772 -12352 -31398 1008419 E ATOM 14739 N ASP E 40 67205 -7304 11024 1006360 E ATOM 14655 CB ALA E 28 65491 -12699 -32137 1009055 E ATOM 14740 CA ASP E 40 65967 -7595 -10308 1006155 E

ATOM 14656 C ALA E 28 67056-10879-31563 1008385 E ATOM 14741 CB ASP E 40 65913 -6794 -8998 10012011 E

ATOM 14657 O ALAE 28 68205-10474-31727 1008487 E ATOM 14742 CG ASP E 40 67131 -7027 -8114 10012225 E

ATOM 14658 N ASN E 29 66012-10066-31521 1004360 E ATOM 14743 ODl ASP E 40 67438 -8204 -7829 10011913 E ATOM 14659 CA ASN E 29 66218 -8647 -31729 1004277 E ATOM 14744 OD2 ASP E 40 67777 -6036 -7700 10012237 E ATOM 14660 CB ASNE 29 65294 -8164-32850 1004399 E ATOM 14745 C ASPE 40 64738 -7275 -11172 1005768 E

ATOM 14661 CG ASN E 29 65599 -8832 -34187 1004405 E ATOM 14746 O ASP E 40 63720 -6784-10684 1005691 E ATOM 14662 ODl ASN E 29 66531 -8443-34893 1004991 E ATOM 14747 N ASN E 41 64850 -7550 -12466 1006350 E ATOM 14663 ND2 ASN E 29 64821 -9852-34531 1004106 E ATOM 14748 CA ASN E 41 63764 -7320 -13420 1005925 E

ATOM 14664 C ASN E 29 65997 -7845 -30458 1004111 E ATOM 14749 CB ASNE 41 62491 -8022-12951 1005381 E

ATOM 14665 O ASN E 29 65122 -6969-30393 1003883 E ATOM 14750 CG ASN E 41 61592 -8402 -14108 1004850 E

ATOM 14666 N ALA E 30 66803 8142 29445 1003419 E ATOM 14751 ODl ASN E 41 62033 -9083-15045 1004984 E ATOM 14667 CA ALA E 30 66711 -7453 -28169 1002901 E ATOM 14752 ND2 ASN E 41 60331 -7968-14060 1004460 E 65251/C766

ATOM 14753 C ASNE 41 63449 -5848 -13706 1006256 E ATOM 14838 C LEU E 52 62392 6350 -23555 1004317 E ATOM 14754 O ASN E 41 62332 -5501 -14100 1006407 E ATOM 14839 O LEU E 52 63198 5440 -23680 1004374 E ATOM 14755 N GLN E 42 64440 -4988-13514 1005770 E ATOM 14840 N ILEE 53 61275 6229-22849 1004246 E ATOM 14756 CA GLN E 42 64258 -3566-13756 005562 E ATOM 14841 CA ILE E 53 60907 4981 -22198 1003906 E ATOM 14757 CB GLN E 42 64178 -2799-12436 005187 E ATOM 14842 CB ILE E 53 60643 5201 -20710 1004582 E ATOM 14758 CG GLN E 42 63231 -3420-11433 005396 E ATOM 14843 CG2 ILE E 53 60320 3892 -20050 1004646 E ATOM 14759 CD GLN E 42 63203 -2685-10107 1005342 E ATOM 14844 CGl ILEE 53 61857 5839-20051 1004471 E ATOM 14760 OEl GLN E 42 64246 2388 9515 1005285 E ATOM 14845 CDl ILEE 53 61640 6120-18590 1004053 E ATOM 14761 NE2 GLN E 42 62OQ0 -2399 -9627 1005518 E ATOM 14846 C ILEE 53 59625 4477-22821 1003912 E ATOM 14762 C GLN E 42 65448 -3070-14542 1005451 E ATOM 14847 O ILEE 53 58715 5264-23093 1004220 E ATOM 14763 O GLN E 42 66551 -3603-14418 1005485 E ATOM 14848 N TYR E 54 59531 3173-23039 1004264 E ATOM 14764 N LEU E 43 65222 -2058 -15366 1004509 E ATOM 14849 CA TYR E 54 58325 2616-23655 1003977 E ATOM 14765 CA LEU E 43 66308 -1489-16144 1004367 E ATOM 14850 CB TYR E 54 58380 2792-25174 1003395 E ATOM 14766 CB LEU E 43 65765 -0892-17440 1004065 E ATOM 14851 CG TYRE 54 59501 2011-25814 1003395 E ATOM 14767 CG LEU E 43 65157 -1921 -18393 1004681 E ATOM 14852 CDl TYR E 54 59321 0691 26207 1003395 E ATOM 14768 CDl LEU E 43 64474 -1207-19540 1004690 E ATOM 14853 CEl TYR E 54 60368 -0049 -26751 1003395 E ATOM 14769 CD2 LEU E 43 66238 -2842-18897 1004320 E ATOM 14854 CD2 TYR E 54 60767 2579 -25985 1003395 E ATOM 14770 C LEU E 43 66939 0410-15280 1004569 E ATOM 14855 CE2 TYR E 54 61825 1846-26530 1003395 E ATOM 14771 O LEU E 43 66226 0334-14605 1004231 E ATOM 14856 CZ TYR E 54 61610 0535-26909 1003395 E ATOM 14772 N VAL E 44 68266 -0330-15284 1004424 E ATOM 14857 OH TYR E 54 62624 -0199 -27469 1003395 E ATOM 14773 CA VAL E 44 68951 0659-14474 1004392 E ATOM 14858 C TYR E 54 58138 1149-23327 1003836 E ATOM 14774 CB VAL E 44 69867 -0006-13447 1004303 E ATOM 14859 O TYR E 54 59075 0451 -22932 1003721 E ATOM 14775 CGl VALE 44 70423 1036 -12504 1004422 E ATOM 14860 N SER E 55 56916 0678-23503 1003338 E ATOM 14776 CG2 VAL E 44 69087 -1044-12673 1003764 E ATOM 14861 CA SERE 55 56602 -0704 -23210 1003316 E ATOM 14777 C VAL E 44 69767 1599-15332 1004293 E ATOM 14862 CB SERE 55 56577 -0924 -21699 1004670 E ATOM 14778 O VALE 44 70708 1178-16017 1004397 E ATOM 14863 OG SERE 55 56071 -2206 -21384 1005326 E ATOM 14779 N VAL E 45 69400 2880 15275 1004696 E ATOM 14864 C SER E 55 55257 -1109 -23778 1003614 E ATOM 14780 CA VAL E 45 70061 3926-16040 1005270 E ATOM 14865 O SER E 55 54349 -0282 -23927 1003328 E ATOM 14781 CB VAL E 45 69233 5208-15964 1004444 E ATOM 14866 N GLN E 56 55132 -2388-24099 1005402 E ATOM 14782 CGl VALE 45 70029 6378-16493 1004701 E ATOM 14867 CA GLN E 56 53876 -2895 -24604 1005472 E ATOM 14783 CG2 VAL E 45 67966 5036-16773 1004784 E ATOM 14868 CB GLN E 56 53861 -2975 -26125 1006297 E ATOM 14784 C VAL E 45 71495 4194-15566 1005449 E ATOM 14869 CG GLNE 56 52489 -3395 -26628 1006457 E ATOM 14785 O VAL E 45 71754 4342 -14375 1005394 E ATOM 14870 CD GLN E 56 52482 -3840 -28071 1006769 E ATOM 14786 N PRO E 46 72449 4258-16503 1004865 E ATOM 14871 OEl GLN E 56 52857 -4970 28385 1006722 E ATOM 14787 CD PRO E 46 72298 3823-17905 1004727 E ATOM 14872 NE2 GLN E 56 52055 -2949 -28963 1007080 E ATOM 14788 CA PRO E 46 73860 4505-16184 1004750 E ATOM 14873 C GLN E 56 53612 -4282 -24064 1005720 E ATOM 14789 CB PRO E 46 74585 3728-17266 1004663 E ATOM 14874 O GLN E 56 54514 -5129-24009 1005528 E ATOM 14790 CG PRO E 46 73719 3992-18458 1004733 E ATOM 14875 N VALE 57 52373 -4510 -23653 1004167 E ATOM 14791 C PRO E 46 74332 5952-16155 1005094 E ATOM 14876 CA VALE 57 51989 -5822 -23163 1003604 E ATOM 14792 O PRO E 46 75484 6209-15819 1005340 E ATOM 14877 CB VALE 57 51638 -5811-21658 1004927 E ATOM 14793 N SER E 47 73474 6900-16521 1006500 E ATOM 14878 CGl VALE 57 52820 -5328 -20853 1005047 E ATOM 14794 CA SERE 47 73899 8296-16519 1006212 E ATOM 14879 CG2 VAL E 57 50429 -4935 -21419 1004620 E ATOM 14795 CB SER E 47 74820 8540-17703 1005136 E ATOM 14880 C VAL E 57 50760 -6219-23953 1003865 E ATOM 14796 OG SERE 47 74141 8249-18907 1005257 E ATOM 14881 O VALE 57 50009 -5358 -24409 1003976 E ATOM 14797 C SER E 47 72757 9298-16562 1005881 E ATOM 14882 N LEU E 58 50568 -7519 -24123 1007353 E ATOM 14798 O SER E 47 71643 8961 16970 1005595 E ATOM 14883 CA LEUE 58 49417 -8019-24850 1007198 E ATOM 14799 N GLU E 48 73049 10529-16129 1006498 E ATOM 14884 CB LEUE 58 49861 -8759-26110 1006910 E ATOM 14800 CA GLU E 48 72080 11631 -16132 1006947 E ATOM 14885 CG LEUE 58 48871 -8789-27277 1007112 E ATOM 14801 CB GLUE 48 72742 12944 15707 10016857 E ATOM 14886 CDl LEU E 58 49214 -9961 -28184 1006514 E ATOM 14802 CG GLU E 48 73444 12931 -14372 10017331 E ATOM 14887 CD2 LEU E 58 47452 -8916-26766 1006890 E ATOM 14803 CD GLU E 48 72508 13138-13199 10017766 E ATOM 14888 C LEU E 58 48674 -8979 -23938 1007495 E ATOM 14804 OEl GLU E 48 71684 12241 -12923 10017940 E ATOM 14889 O LEUE 58 49209-10015-23546 1007658 E ATOM 14805 OE2 GLU E 48 72598 14206-12554 10017558 E ATOM 14890 N PHE E 59 47445 -8630 -23585 1007498 E ATOM 14806 C GLU E 48 71629 11793-17579 1006806 E ATOM 14891 CA PHEE 59 46647 -9489 -22723 1007588 E ATOM 14807 O GLU E 48 72394 11518-18508 1007385 E ATOM 14892 CB PHE E 59 45781 -8664-21769 1006918 E ATOM 14808 N GLY E 49 70391 12228-17781 1003938 E ATOM 14893 CG PHE E 59 46560 7883 -20757 1006567 E ATOM 14809 CA GLY E 49 69940 12430 -19142 1003704 E ATOM 14894 CDl PHEE 59 46753 -6513-20914 1006411 E ATOM 14810 C GLY E 49 68464 12276-19428 1003905 E ATOM 14895 CD2 PHE E 59 47096 -8511-19641 1006763 E ATOM 14811 O GLY E 49 67676 11869-18571 1004189 E ATOM 14896 CEl PHE E 59 47463 -5780-19974 1007003 E ATOM 14812 N LEU E 50 68120 12626-20663 1004762 E ATOM 14897 CE2 PHE E 59 47813 -7786-18692 1007074 E ATOM 14813 CA LEUE 50 66769 12547-21184 1004882 E ATOM 14898 CZ PHE E 59 47995 -6415-18860 1006934 E ATOM 14814 CB LEU E 50 66592 13618-22260 1003861 E ATOM 14899 C PHEE 59 45744-10361 -23576 1007999 E ATOM 14815 CG LEUE 50 65628 14791 -22018 1003974 E ATOM 14900 O PHEE 59 45272 -9928 -24624 1007968 E ATOM 14816 CDl LEU E 50 65523 15123-20545 1003655 E ATOM 14901 N LYSE 60 45511 -11588-23121 1009425 E ATOM 14817 CD2 LEU E 50 66098 16001 -22807 1004013 E ATOM 14902 CA LYS E 60 44652 -12529 -23827 1009560 E ATOM 14818 C LEU E 50 66644 11153-21789 1004520 E ATOM 14903 CB LYS E 60 45480-13457-24713 1008356 E ATOM 14819 O LEU E 50 67503 10726 -22567 1004392 E ATOM 14904 CG LYS E 60 44662 -14527 -25414 1008975 E ATOM 14820 N TYR E 51 65594 10429 21419 1004287 E ATOM 14905 CD LYS E 60 45566 -15463 -26200 1009796 E ATOM 14821 CA TYRE 51 65393 9076 -21945 1004152 E ATOM 14906 CE LYS E 60 44777-16570-26882 10010071 E ATOM 14822 CB TYRE 51 65616 8010-20862 1004078 E ATOM 14907 NZ LYS E 60 45672-17422-27712 10010105 E ATOM 14823 CG TYRE 51 67042 7783 -20447 1004088 E ATOM 14908 C LYS E 60 43884 -13358 -22816 1009511 E ATOM 14824 CDlTYRE 51 67714 8711 -19655 1004174 E ATOM 14909 O LYSE 60 44440-13798 21808 1009786 E ATOM 14825 CElTYRE 51 69026 8499-19257 1004130 E ATOM 14910 N GLYE 61 42603 -13567 -23087 1007145 E ATOM 14826 CD2TYRE 51 67720 6631 -20837 1004244 E ATOM 14911 CA GLYE 61 41793-14351-22185 1007401 E ATOM 14827 CE2TYRE 51 69034 6406 -20448 1004071 E ATOM 14912 C GLY E 61 40801 -15205-22939 1007571 E ATOM 14828 CZ TYRE 51 69684 7343-19656 1004041 E ATOM 14913 O GLY E 61 40271 -14785 -23967 1007888 E ATOM 14829 OH TYRE 51 70995 7129-19258 1004064 E ATOM 14914 N GLN E 62 40560-16412-22432 10012157 E ATOM 14830 C TYRE 51 64003 8834 -22506 1004170 E ATOM 14915 CA GLN E 62 39605-17329-23041 10012188 E ATOM 14831 O TYRE 51 63002 9312-21968 1004259 E ATOM 14916 CB GLN E 62 39989-18776-22737 10012287 E ATOM 14832 N LEUE 52 63947 8076 -23590 1003999 E ATOM 14917 CG GLN E 62 41388-19153-23182 10012700 E ATOM 14833 CA LEU E 52 62670 7719 -24174 1004164 E ATOM 14918 CD GLN E 62 41555 -19101 -24687 10013294 E ATOM 14834 CB LEU E 52 62765 7632 -25705 1005653 E ATOM 14919 OEl GLN E 62 41377-18054-25310 10013254 E ATOM 14835 CG LEUE 52 61560 6986-26399 1005242 E ATOM 14920 NE2 GLN E 62 41901 -20237-25281 10013311 E ATOM 14836 CDl LEU E 52 60270 7664 -25960 1005445 E ATOM 14921 C GLN E 62 38254-17017-22420 10011982 E ATOM 14837 CD2 LEU E 52 61742 7063 -27909 1004675 E ATOM 14922 O GLNE 62 38095-17111 21204 10012133 E 65251/C766

ATOM 14923 N GLYE 63 37288-16634-23249 10011001 E ATOM 15008 C THRE 74 53985 0890-15638 1006044 E ATOM 14924 CA GLY E 63 35968-16308-22734 10010800 E ATOM 15009 O THRE 74 54551 -0120-15220 1005602 E ATOM 14925 C GLY E 63 36042-15255-21644 10010608 E ATOM 15010 N ILEE 75 54642 1983-16022 1005214 E ATOM 14926 O GLYE 63 37089-14645-21441 10010412 E ATOM 15011 CA ILEE 75 56087 2081 -15910 1005344 E ATOM 14927 N CYSE 64 34946 15049 20923 10013773 E ATOM 15012 CB ILE E 75 56710 2670-17183 1004095 E ATOM 14928 CA CYS E 64 34931-14042-19872 10014197 E ATOM 15013 CG2 ILE E 75 58203 2878-16995 1004044 E ATOM 14929 C CYS E 64 34779-14523-18433 10014806 E ATOM 15014 CGl ILE E 75 56462 1730-18356 1003811 E ATOM 14930 O CYS E 64 34032-15459-18147 10015097 E ATOM 15015 CDl ILE E 75 57057 2218-19651 1004140 E ATOM 14931 CB CYS E 64 33852-13005-20168 10015470 E ATOM 15016 C ILEE 75 56389 2997 14736 1005658 E ATOM 14932 SG CYS E 64 34413-11783-21382 10015591 E ATOM 15017 O ILEE 75 55940 4152-14709 1005335 E ATOM 14933 N PROE 65 35507 -13878 -17504 10013404 E ATOM 15018 N SER E 76 57140 2478-13766 1006008 E ATOM 14934 CD PRO E 65 36641-12983-17790 10016207 E ATOM 15019 CA SERE 76 57492 3245-12576 1006116 E ATOM 14935 CA PRO E 65 35471-14214-16079 10013638 E ATOM 15020 CB SERE 76 57184 2448-11314 1005571 E ATOM 14936 CB PRO E 65 36683-13470-15514 10016460 E ATOM 15021 OG SERE 76 55829 2058 -11264 1006500 E ATOM 14937 CG PRO E 65 37600-13345-16691 10016433 E ATOM 15022 C SERE 76 58956 3619-12529 1005716 E ATOM 14938 C PRO E 65 34171 -13746-15433 10013939 E ATOM 15023 O SER E 76 59800 2958-13129 1005331 E ATOM 14939 O PRO E 65 33131-13642-16086 10013966 E ATOM 15024 N ARG E 77 59249 4693-11808 1004278 E ATOM 14940 N SER E 66 34248-13455-14142 10016038 E ATOM 15025 CA ARG E 77 60618 5130-11627 1004796 E ATOM 14941 CA SERE 66 33097-12995 13391 10016398 E ATOM 15026 CB ARG E 77 60841 6552-12152 1005024 E ATOM 14942 CB SERE 66 33111 -13617-11995 10016226 E ATOM 15027 CG ARG E 77 62053 7215-11501 1005242 E ATOM 14943 OG SER E 66 32016 13162 11222 10015942 E ATOM 15028 CD ARG E 77 62654 8322-12336 1005329 E ATOM 14944 C SER E 66 33115-11475-13282 10016453 E ATOM 15029 NE ARG E 77 62397 9661-11812 1005573 E ATOM 14945 O SER E 66 34053-10821 -13743 10015795 E ATOM 15030 CZ ARG E 77 63352 10552-11553 1005916 E ATOM 14946 N THRE 67 32068 10931-12669 10020084 E ATOM 15031 NHl ARG E 77 63034 11753 -11092 1005925 E ATOM 14947 CA THR E 67 31912 -9493-12461 10020084 E ATOM 15032 NH2 ARG E 77 64629 10238-11 739 1005902 E ATOM 14948 CB THR E 67 32406 -9077-11051 10017447 E ATOM 15033 C ARG E 77 60873 5118-10137 1004630 E ATOM 14949 OGl THRE 67 31765 -9888-10059 10017447 E ATOM 15034 O ARG E 77 60040 5574 -9354 1005205 E ATOM 14950 CG2 THR E 67 32081 -7609-10778 10017447 E ATOM 15035 N ILEE 78 61999 4549 -9736 1004477 E ATOM 14951 C THR E 67 32628 -8626-13494 0020084 E ATOM 15036 CA ILE E 78 62369 4573 -8331 1004346 E ATOM 14952 O THR E 67 32123 -8406-14596 0020084 E ATOM 15037 CB ILEE 78 62450 3125 -7685 1007229 E ATOM 14953 N HIS E 68 33812 -8142-13130 10017233 E ATOM 15038 CG2 ILE E 78 61795 2095 -8579 1007279 E ATOM 14954 CA HIS E 68 34583 -7281 -14011 10016745 E ATOM 15039 CGl ILEE 78 63886 2739 -7374 1007396 E ATOM 14955 CB HIS E 68 34190 -5824 -13759 10018877 E ATOM 15040 CDl ILEE 78 64461 3489 -6200 1007428 E ATOM 14956 CG HIS E 68 34490 4907-14901 10018877 E ATOM 15041 C ILE E 78 63708 5303 -8432 1004563 E ATOM 14957 CD2 HIS E 68 35280 -3811-14982 10018877 E ATOM 15042 O ILEE 78 64721 4739 -8838 1004418 E ATOM 14958 NDl HIS E 68 33923 -5064-16148 10018877 E ATOM 15043 N ALA E 79 63667 6596 -8118 1005397 E ATOM 14959 CEl HIS E 68 34351 -4103-16947 10018877 E ATOM 15044 CA ALAE 79 64837 7457 -8216 1005057 E ATOM 14960 NE2 HIS E 68 35174 -3329 -16264 I 0018877 E ATOM 15045 CB ALAE 79 64394 8912 -8195 1005211 E ATOM 14961 C HISE 68 36077 -7468-13763 10016328 E ATOM 15046 C ALA E 79 65898 7222 -7152 1005177 E ATOM 14962 O HlSE 68 36507 -7662 -12627 10016273 E ATOM 15047 O ALA E 79 65595 6815 -6040 1005197 E ATOM 14963 N VALE 69 36862 -7412-14835 10010920 E ATOM 15048 N VALE 80 67152 7482 -7502 1006497 E ATOM 14964 CA VAL E 69 38311 -7565-14740 10010893 E ATOM 15049 CA VALE 80 68250 7311 -6560 1006746 E ATOM 14965 CB VAL E 69 38807 -8798 -15540 10013079 E ATOM 15050 CB VALE 80 69610 7599 -7223 1007548 E ATOM 14966 CGl VAL E 69 40309 -8954-15380 10013055 E ATOM 15051 CGl VALE 80 70724 7459 -6202 1007388 E ATOM 14967 CG2 VAL E 69 38097 -10051 -15064 10012905 E ATOM 15052 CG2 VAL E 80 69836 6649 -8374 1007718 E ATOM 14968 C VAL E 69 39004 -6319-15287 10010852 E ATOM 15053 C VALE 80 68072 8278 -5398 1007201 E ATOM 14969 O VAL E 69 38644 -5807-16350 10011208 E ATOM 15054 O VALE 80 68426 7969 -4262 1007060 E ATOM 14970 N LEU E 70 39993 -5828-14547 1008316 E ATOM 15055 N SERE 81 67515 9451 -5685 1006809 E ATOM 14971 CA LEU E 70 40742 -4655-14971 1007838 E ATOM 15056 CA SERE 81 67305 10461 -4656 1007095 E ATOM 14972 CB LEUE 70 40736 -3576-13889 1007301 E ATOM 15057 CB SERE 81 67505 11 858 5239 1005247 E ATOM 14973 CG LEU E 70 39411 -2875-13595 1007471 E ATOM 15058 OG SERE 81 68851 12059 -5626 1005551 E ATOM 14974 CDl LEU E 70 39653 -1779-12575 1006975 E ATOM 15059 C SERE 81 65941 10389 -3973 1007513 E ATOM 14975 CD2 LEU E 70 38830 -2289-14866 1007531 E ATOM 15060 O SERE 81 65598 11278 3193 1007565 E ATOM 14976 C LEU E 70 42180 -5018-15290 1007942 E ATOM 15061 N TYRE 82 65169 9340 -4261 1005208 E ATOM 14977 O LEU E 70 42831 -5749-14541 1007953 E ATOM 15062 CA TYR E 82 63848 9158 -3654 1005412 E ATOM 14978 N LEU E 71 42665 -4502 -16414 1007180 E ATOM 15063 CB TYRE 82 62849 10166 -4230 1005525 E ATOM 14979 CA LEUE 71 44033 -4740 -16849 1007174 E ATOM 15064 CG TYRE 82 61528 10215 -3489 1005845 E ATOM 14980 CB LEU E 71 44047 -5239-18294 1005946 E ATOM 15065 CDl TYR E 82 60330 9973 -4147 1006074 E ATOM 14981 CG LEUE 71 43297 -6545-18562 1005713 E ATOM 15066 CEl TYR E 82 59122 9987 -3465 1006253 E ATOM 14982 CDl LEU E 71 43313 -6863-20042 1005328 E ATOM 15067 CD2 TYR E 82 61482 10479 -2123 1006054 E ATOM 14983 CD2 LEU E 71 43941 -7668-17776 1005725 E ATOM 15068 CE2TYRE 82 60281 10498 -1433 1006201 E ATOM 14984 C LEU E 71 44797 -3426 -16753 1007577 E ATOM 15069 CZ TYR E 82 59104 10247 -2108 1006270 E ATOM 14985 O LEU E 71 44360 -2411 -17294 1007526 E ATOM 15070 OH TYRE 82 57909 10235 -1424 10061 12 E ATOM 14986 N THR E 72 45924 -3439 -16048 1007794 E ATOM 15071 C TYRE 82 63343 7742 -3903 1005355 E ATOM 14987 CA THRE 72 46727 -2233 -15905 1007537 E ATOM 15072 O TYR E 82 62443 7535 -4715 1005373 E ATOM 14988 CB THR E 72 46730 -1686-14456 1007384 E ATOM 15073 N GLN E 83 63930 6779 -3190 1006100 E ATOM 14989 OGlTHRE 72 47595 -2487 -13641 1007637 E ATOM 15074 CA GLNE 83 63601 5361 -3317 1006089 E ATOM 14990 CG2THRE 72 45331 -1699-13876 1007156 E ATOM 15075 CB GLN E 83 64401 4532 -2315 1007795 E ATOM 14991 C THR E 72 48168 -2487-16297 1007800 E ATOM 15076 CG GLN E 83 65649 3877 -2852 1008222 E ATOM 14992 O THR E 72 48739 -3547 -16020 1007904 E ATOM 15077 CD GLNE 83 66794 4847 -3011 1008326 E ATOM 14993 N HIS E 73 48747 -1493-16951 1004948 E ATOM 15078 OEl GLN E 83 67938 4438 -3203 1008228 E ATOM 14994 CA HIS E 73 50128 1553-17388 1004993 E ATOM 15079 NE2GLNE 83 66497 6143 -2935 1008076 E ATOM 14995 CB HIS E 73 50206 -1623-18909 1005445 E ATOM 15080 C GLN E 83 62138 4975 -3164 1005907 E ATOM 14996 CG HIS E 73 51597 1779-19425 1005732 E ATOM 15081 O GLNE 83 61765 4375 -2168 1005652 E ATOM 14997 CD2 HIS E 73 52729 -2210-18820 1005908 E ATOM 15082 N THR E 84 61304 5289 -4144 1008405 E ATOM 14998 NDl HIS E 73 51939 -1499-20730 1006193 E ATOM 15083 CA THR E 84 59902 4910 -4064 1007642 E ATOM 14999 CEl HIS E 73 53225 -1753 -20906 1006047 E ATOM 15084 CB THRE 84 59069 5915 -3276 1009169 E ATOM 15000 NE2 HIS E 73 53727 -2185-19763 1006064 E ATOM 15085 OGl THR E 84 59698 6170 -2020 1009224 E ATOM 15001 C HIS E 73 50716 -0248-16910 1004901 E ATOM 15086 CG2THRE 84 57673 5364 -3035 1009444 E ATOM 15002 O HIS E 73 50115 0804-17106 1004487 E ATOM 15087 C THRE 84 59336 4872 -5456 1007293 E ATOM 15003 N THR E 74 51880 -0296-16278 1005500 E ATOM 15088 O THRE 84 59611 5750 -6271 1007424 E ATOM 15004 CA THRE 74 52463 0937-15780 1006159 E ATOM 15089 N LYS E 85 58545 3850 -5735 1005381 E ATOM 15005 CB THRE 74 51776 1341 -14418 1005450 E ATOM 15090 CA LYS E 85 57930 3743 -7037 1005367 E ATOM 15006 OGl THR E 74 52765 1707-13448 1005701 E ATOM 15091 CB LYS E 85 57099 2466 -7140 1008264 E ATOM 15007 CG2 THR E 74 50942 0191 -13870 1005933 E ATOM 15092 CG LYS E 85 57817 1259 7703 1007958 E 65251/C766

ATOM 15093 CD LYS E 85 56807 0143 -7952 1007798 E ATOM 15178 CB GLNE 97 31970 ^ 794 -21024 10014365 E

ATOM 15094 CE LYS E 85 57436 -1038 8668 1007628 E ATOM 15179 CG GLN E 97 33031 -4213 -21946 10014365 E

ATOM 15095 NZ LYSE 85 58525 -1683 -7877 1007453 E ATOM 15180 CD GLN E 97 32466 -3776 -23286 10014365 E

ATOM 15096 C LYS E 85 56999 4928 -7254 1005347 E ATOM 15181 OEl GLN E 97 31572 -2932-23353 10014365 E

ATOM 15097 O LYS E 85 56105 5166 -6448 1005392 E ATOM 15182 NE2 GLN E 97 32988 -4351 -24364 10014365 E

ATOM 15098 N VALE 86 57235 5684 -8325 1005716 E ATOM 15183 C GLNE 97 31419 -6328-19120 10020040 E

ATOM 15099 CA VALE 86 56360 6792 -8699 1006005 E ATOM 151840 GLNE 97 30247 -5989-19282 10020040 E

ATOM 15100 CB VALE 86 57034 8199 -8550 1006503 E ATOM 15185 N ARGE 98 31791 -7324-18314 10020084 E

ATOM 15101 CG 1 VAL E 86 57383 8451 -7100 1007177 E ATOM 15186 CA ARGE 98 30841 -8117 17529 10020084 E

ATOM 15102 CG2 VAL E 86 58267 8300 -9399 1006630 E ATOM 15187 CB ARGE 98 29893 -7184-16756 10018926 E

ATOM 15103 C VALE 86 56031 6495-10157 1006072 E ATOM 15188 CG ARGE 98 28744 -7876-16030 10018926 E

ATOM 15104 O VALE 86 56918 6238-10963 1006541 E ATOM 15189 CD ARGE 98 29227 8810 14934 10018926 E

ATOM 15105 N ASN E 87 54750 6486-10483 1006140 E ATOM 15190 NE ARG E 98 28135 -9622 -14403 10018926 E

ATOM 15106 CA ASN E 87 54333 6188-11842 1005808 E ATOM 15191 CZ ARGE 98 27013 -9129-13888 10018926 E

ATOM 15107 CB ASN E 87 52828 5937 -11864 1005696 E ATOM 15192 NHl ARGE 98 26078 9951-13431 10018926 E

ATOM 15108 CG ASN E 87 52444 4669-11142 1005726 E ATOM 15193 NH2 ARGE 98 26823 -7817-13827 10018926 E

ATOM 15109 ODl ASN E 87 53302 3886-10732 1005987 E ATOM 15194 C ARGE 98 30041 -9102-18397 10020084 E

ATOM 15110 ND2ASNE 87 51148 4448-10995 1005422 E ATOM 15195 0 ARGE 98 29177 -9825-17896 10020084 E

ATOM 15111 C ASN E 87 54684 7259-12868 1005690 E ATOM 15196 N GLUE 99 30347 -9138-19695 10020084 E

ATOM 15112 O ASNE 87 54418 8443-12651 1005548 E ATOM 15197 CA GLU E 99 29662 -10032 -20630 10020084 E

ATOM 15113 N LEU E 88 55274 6845 -13989 1005759 E ATOM 15198 CB GLUE 99 30458-10167-21935 10016454 E

ATOM 15114 CA LEUE 88 55618 7785-15054 1005658 E ATOM 15199 CG GLUE 99 31834 -9514-21916 10016454 E

ATOM 15115 CB LEU E 88 56984 7477-15650 1003578 E ATOM 15200 CD GLUE 99 31788 -8038-22267 10016454 E

ATOM 15116 CG LEUE 88 58179 7553 14720 1003271 E ATOM 15201 OElGLUE 99 30894 -7332-21754 10016454 E

ATOM 15117 CDl LEUE 88 59432 7248-15518 1003348 E ATOM 15202 OE2GLUE 99 32651 -7582-23049 10016454 E

ATOM 15118 CD2 LEU E 88 58242 8927-14084 1003128 E ATOM 15203 C GLU E 99 29434-11422-20041 10020084 E

ATOM 15119 C LEU E 88 54586 7670 16157 1005582 E ATOM 152040 GLUE 99 28317-11936-20076 10020084 E

ATOM 15120 O LEU E 88 54119 8667-16695 1005429 E ATOM 15205 N THRElOO 30498-12016-19502 10020084 E

ATOM 15121 N LEU E 89 54234 6435-16487 1005156 E ATOM 15206 CA THRElOO 30448-13349-18900 10020084 E

ATOM 15122 CA LEUE 89 53264 6167-17532 1005048 E ATOM 15207 CB THRElOO 29760-13319-17508 10016816 E

ATOM 15123 CB LEUE 89 53987 5737-18808 1004269 E ATOM 15208 OGl THR E 100 28455-12742 17625 10016844

ATOM 15124 CG LEUE 89 55088 6659-19325 1004667 E E

ATOM 15125 CDl LEU E 89 55995 5860 -20242 1004640 E ATOM 15209 CG2THRE100 30581 -12502-16520 10016933

ATOM 15126 CD2 LEU E 89 54496 7847 -20046 1004579 E E

ATOM 15127 C LEU E 89 52364 5040-17046 1005215 E ATOM 15210 C THRElOO 29730-14367-19789 10020084 E

ATOM 15128 O LEU E 89 52837 4091 -16418 1005287 E ATOM 15211 O THRElOO 28534-14251-20050 10020084 E

ATOM 15129 N SER E 90 51074 5137-17340 1004409 E ATOM 15212 N PROElOl 30462-15389-20261 10019062 E

ATOM 15130 CA SERE 90 50139 4114-16913 I 004343 E ATOM 15213 CD PRO E 101 31871 -15675 -19939 10013211 E

ATOM 15131 CB SER E 90 49812 4301-15436 1007567 E ATOM 15214 CA PRO E 101 29909 -16436 -21124 10019062 E

ATOM 15132 OG SERE 90 48839 3361-15015 1007989 E ATOM 15215 CB PROElOl 30971-17528-21052 10013306 E

ATOM 15133 C SER E 90 48849 4138-17705 1004206 E ATOM 15216 CG PROElOl 32230-16735-20961 10013109 E

ATOM 15134 O SER E 90 48386 5194-18117 1004188 E ATOM 15217 C PROElOl 28532-16928-20683 10019062 E

ATOM 15135 N ALA E 91 48261 2970-17918 1004967 E ATOM 15218 0 PROElOl 28393-17573-19644 10019062 E

ATOM 15136 CA ALA E 91 47000 2896-18636 1004776 E ATOM 15219 N GLUE102 27522-16612-21487 10018084 E

ATOM 15137 CB ALAE 91 47248 2693-20115 1003473 E ATOM 15220 CA GLU E 102 26145-17008-21216 10018084 E

ATOM 15138 C ALA E 91 46177 1751 -18066 1005173 E ATOM 15221 CB GLUE102 25289-16749-22465 10015009 E

ATOM 15139 O ALAE 91 46721 0834-17435 1005360 E ATOM 15222 CG GLU E 102 23834-17189-22366 10015129 E

ATOM 15140 N ILEE 92 44865 1818-18275 1006053 E ATOM 15223 CD GLU E 102 23666 -18697 -22446 10015260 E

ATOM 15141 CA ILE E 92 43948 0794-17783 1006051 E ATOM 15224 OEl GLU E 102 24074-19292-23468 10015341

ATOM 15142 CB ILE E 92 43077 1342-16651 1006986 E E

ATOM 15143 CG2 ILE E 92 42236 0233-16072 1007593 E ATOM 15225 OE2 GLU E 102 23125 -19285 -21485 I 0015172

ATOM 15144 CGl ILEE 92 43961 1940-15557 1006797 E E

ATOM 15145 CDl ILE E 92 43196 2666-14477 1007384 E ATOM 15226 C GLU E 102 26043-18476-20790 1 0017740

ATOM 15146 C ILEE 92 43040 0360-18917 1006034 E ATOM 15227 O GLU E 102 25267-18820-19897 10017446

ATOM 15147 O ILE E 92 42701 1171 -19775 1006142 E ATOM 15228 N GLY E 103 26835-19335-21427 10012536

ATOM 15148 N LYS E 93 42641 -0907-18929 1007672 E ATOM 15229 CA GLY E 103 26815-20753-21106 10012268

ATOM 15149 CA LYS E 93 41771 -1398-19987 1007737 E ATOM 15230 C GLY E 103 27144-21607-22318 10012055

ATOM 15150 CB LYS E 93 42615 -2002-21113 1008735 E ATOM 15231 O GLY E 103 27381 -22812-22202 10011504

ATOM 15151 CG LYS E 93 41988 -1884-22491 1009104 E ATOM 15232 N ALA E 104 27155-20975-23488 10018508

ATOM 15152 CD LYS E 93 43050 -1935 -23583 1009081 E ATOM 15233 CA ALA E 104 27460-21659-24739 10018508

ATOM 15153 CE LYS E 93 42455 -1671 -24974 1009071 E ATOM 15234 CB ALA E 104 26166-21953-25505 1008710

ATOM 15154 NZ LYS E 93 43480 -1654 -26072 1009328 E ATOM 15235 C ALA E 104 28394 -20798 -25590 10018508

ATOM 15155 C LYS E 93 40816 -2435-19418 1007907 E ATOM 15236 O ALA E 104 28015-19708-26018 10018508

ATOM 15156 O LYS E 93 41225 -3304 -18644 1007699 E ATOM 15237 N GLU E 105 29610-21300-25814 10017409

ATOM 15157 N SER E 94 39544 -2331 19796 1007463 E ATOM 15238 CA GLU E 105 30653 -20635 -26608 10017409

ATOM 15158 CA SERE 94 38502 -3249-19329 1007708 E ATOM 15239 CB GLU E 105 30044-19649-27615 10015526

ATOM 15159 CB SER E 94 37284 -2453-18856 10011938 E ATOM 15240 CG GLU E 105 29235 -20301 -28723 10015526

ATOM 15160 OG SERE 94 36770 -1634-19897 10012181 E ATOM 15241 CD GLU E 105 30065-21251 -29563 10015526

ATOM 15161 C SER E 94 38076 -4206 -20439 1007967 E ATOM 15242 OEl GLU E 105 30535 -22273 -29022 10015526

ATOM 15162 O SER E 94 37218 -3873-21258 1008094 E E

ATOM 15163 N PRO E 95 38653 -5419-20465 1006827 E ATOM 15243 OE2 GLU E 105 30251 -20973 -30765 10015403

ATOM 15164 CD PROE 95 39494 -6002 -19404 10011708 E E

ATOM 15165 CA PRO E 95 38333 -6425-21484 1007221 E ATOM 15244 C GLU E 105 31713-19914-25774 10017409 E

ATOM 15166 CB PRO E 95 39306 -7553 -21160 10012002 E ATOM 15245 O GLU E 105 32398 -20533 -24957 I 0017409 E

ATOM 15167 CG PROE 95 39377 -7490-19673 10011747 E ATOM 15246 N ALA E 106 31846 -18608 -26006 10016637 E

ATOM 15168 C PRO E 95 36879 -6875-21435 007664 E ATOM 15247 CA ALA E 106 32810-17748-25314 10016637 E

ATOM 15169 O PRO E 95 36054 -6456-22251 008007 E ATOM 15248 CB ALA E 106 32981 -18191 -23854 1008177 E

ATOM 15170 N CYS E 96 36573 -7737-20474 0018354 E ATOM 15249 C ALA E 106 34165-17727-26021 10016637 E

ATOM 15171 CA CYS E 96 35225 -8245-20316 10018333 E ATOM 15250 O ALA E 106 35092-18437-25629 10016637 E

ATOM 15172 C CYS E 96 34355 -7220-19618 10018443 E ATOM 15251 N LYS E 107 34270-16905-27064 10015878 E

ATOM 15173 O CYS E 96 34497 -6974-18421 10018473 E ATOM 15252 CA LYS E 107 35502-16769-27843 10015290 E

ATOM 15174 CB CYS E 96 35246 -9548 -19522 10020084 E ATOM 15253 CB LYS E 107 35244-15939-29109 10018517 E

ATOM 15175 SG CYS E 96 35997 -10928 -20440 10020084 E ATOM 15254 CG LYS E 107 34504-16657-30236 10018512 E

ATOM 15176 N GLN E 97 33460 6614 -20387 10020040 E ATOM 15255 CD LYS E 107 33082-17031 -29857 10018655 E

ATOM 15177 CA GLNE 97 32544 -5613 -19866 10020040 E ATOM 15256 CE LYS E 107 32323-17559-31063 10018259 E 65251/C766

ATOM 15257 NZ LYS E 107 33032-18694-31716 10018285 E ATOM 15342 CA GLY E 117 57248 9142-23053 1004389 E ATOM 15258 C LYS E 107 36612-16100-27032 10014838 E ATOM 15343 C GLYE 117 58713 9455-22774 1004520 E

ATOM 15259 O LYS E 107 36363-15563-25952 10014751 E ATOM 15344 O GLYE 117 59519 8540-22577 1004658 E

ATOM 15260 N PROE108 37858-16134-27541 10010133 E ATOM 15345 N VALE118 59061 10742 -22757 1004478 E

ATOM 15261 CD PROE108 38334-16909-28704 1009061 E ATOM 15346 CA VALE118 60436 11174-22503 1004756 E

ATOM 15262 CA PRO E 108 38987-15515-26841 10010007 E ATOM 15347 CB VAL E 118 60835 12279-23483 1003669 E

ATOM 15263 CB PRO E 108 40189-16268-27402 1008976 E ATOM 15348 CGl VAL E 118 62228 12783-23165 1003809 E

ATOM 15264 CG PRO E 108 39794-16472-28824 1008714 E ATOM 15349 CG2VALE118 60776 11744-24903 1003675 E

ATOM 15265 C PROElOS 39047-14019-27146 1009930 E ATOM 15350 C VALE118 60580 11673 21065 1004547 E

ATOM 15266 O PRO E 108 38480-13558-28139 1009748 E ATOM 15351 O VALE 118 59719 12393-20577 1004942 E ATOM 15267 N TRP E 109 39718-13264-26282 10010666 E ATOM 15352 N PHEE119 61660 11281-20388 1004803 E

ATOM 15268 CA TRPE109 39856-11827-26479 10010411 E ATOM 15353 CA PHEE119 61869 11662-18990 1004934 E

ATOM 15269 CB TRP E 109 38985-11048-25493 1009692 E ATOM 15354 CB PHEE 119 61372 10559-18056 1003483 E

ATOM 15270 CG TRPE 109 39218-11385-24050 1009661 E ATOM 15355 CG PHEE 119 59904 10273-18179 1003243 E

ATOM 15271 CD2 TRP E 109 40243-10861-23193 1009562 E ATOM 15356 CDl PHE E 119 59414 9447-19187 1003062 E

ATOM 15272 CE2 TRP E 109 40068-11452-21922 1009487 E ATOM 15357 CD2 PHE E 119 58995 10855-17305 1003111 E

ATOM 15273 CE3 TRP E 109 41292 -9951 -23375 1009572 E ATOM 15358 CEl PHE E 119 58033 9212 19318 1003169 E

ATOM 15274 CDl TRP E 109 38490-12248-23286 1009371 E ATOM 15359 CE2 PHE E 119 57620 10624-17428 1003192 E

ATOM 15275 NEl TRP E 109 38991 -12293-22008 1009203 E ATOM 15360 CZ PHEE 119 57140 9807-18430 1003101 E

ATOM 15276 CZ2 TRP E 109 40902-11165-20838 1009132 E ATOM 15361 C PHE E 119 63309 11973-18613 1005025 E

ATOM 15277 CZ3 TRP E 109 42123 -9666-22294 1009548 E ATOM 15362 O PHE E 119 64250 11434-19201 1004635 E ATOM 15278 CH2 TRP E 109 41920-10272-21043 1009112 E ATOM 15363 N GLNE120 63460 12850-17620 1004140 E

ATOM 15279 C TRP E 109 41299-11373-26331 10010572 E ATOM 15364 CA GLN E 120 64764 13247-17093 1004477 E

ATOM 15280 O TRP E 109 42061 11917 25525 10010733 E ATOM 15365 CB GLN E 120 64670 14611-16412 1008423 E

ATOM 15281 N TYREIlO 41665-10375-27128 1006464 E ATOM 15366 CG GLN E 120 65581 15686-16985 1008438 E

ATOM 15282 CA TYREIlO 43009 -9818-27098 1006328 E ATOM 15367 CD GLN E 120 67038 15262-17039 1008398 E

ATOM 15283 CB TYREIlO 43710-10037-28435 1006992 E ATOM 15368 OEl GLN E 120 67542 14629-16116 1008354 E

ATOM 15284 CG TYREIlO 43943-11487-28793 1007347 E ATOM 15369 NE2 GLN E 120 67727 15624-18118 1008681 E

ATOM 15285 CDl TYR E 110 42889-12309-29202 1007756 E ATOM 15370 C GLN E 120 65087 12187-16046 004391 E

ATOM 15286 CEl TYR E 110 43115-13637-29573 1007788 E ATOM 15371 O GLN E 120 64302 11987-15129 004661 E

ATOM 15287 CD2 TYR E 110 45230-12032-28757 1007370 E ATOM 15372 N LEU E 121 66223 11502-16186 004631 E

ATOM 15288 CE2 TYR E 110 45464-13353-29125 1007907 E ATOM 15373 CA LEUE 121 66615 10449-15242 1004797 E ATOM 15289 CZ TYREIlO 44408-14149-29532 1007936 E ATOM 15374 CB LEU E 121 66591 9092-15939 1004608 E

ATOM 15290 OH TYREIlO 44665-15449-29905 1008056 E ATOM 15375 CG LEU E 121 65310 S 270 15897 1004435 E

ATOM 15291 C TYREIlO 42916 -8325-26811 1006179 E ATOM 15376 CDl LEU E 121 64107 9163-15796 1004574 E

ATOM 15292 0 TYREIlO 42051 -7633-27349 1006298 E ATOM 15377 CD2 LEU E 121 65242 7383-17133 1003984 E

ATOM 15293 N GLUElIl 43813 -7836-25964 1005715 E ATOM 15378 C LEU E 121 68001 10668-14652 1005001 E

ATOM 15294 CA GLUElIl 43835 -6427-25595 1005517 E ATOM 15379 O LEU E 121 68876 11247-15305 1005528 E

ATOM 15295 CB GLUElIl 43028 -6219-24317 1007791 E ATOM 15380 N GLU E 122 68189 10195-13420 1006326 E

ATOM 15296 CG GLUElIl 42178 -4985-24342 1008483 E ATOM 15381 CA GLUE 122 69461 10313-12697 1006480 E

ATOM 15297 CD GLUElIl 41158 -5021-25456 1008980 E ATOM 15382 CB GLUE122 69242 10492-11194 10010081 E

ATOM 15298 OEl GLUElIl 40330 -5955-25465 1009001 E ATOM 15383 CG GLUE 122 68474 11699-10724 10010385 E

ATOM 15299 OE2 GLU E 111 41180 -4119-26322 1009696 E ATOM 15384 CD GLU E 122 68255 11655 -9211 10010913 E

ATOM 15300 C GLUElIl 45270 -5951-25371 1005575 E ATOM 15385 OEl GLU E 122 67585 10714 -8728 10011063 E

ATOM 15301 O GLUElIl 45922 -6338-24396 1006111 E ATOM 15386 OE2 GLU E 122 68760 12553 -8502 10010922 E

ATOM 15302 N PRO E 112 45793 -5124-26289 1005756 E ATOM 15387 C GLU E 122 70252 9027-12841 1006360 E

ATOM 15303 CD PROE112 45274 -4911 -27655 1005225 E ATOM 15388 O GLUE122 69669 7952-12959 1006479 E

ATOM 15304 CA PROE 112 47161 -4602-26169 1005679 E ATOM 15389 N LYS E 123 71575 9124-12805 1006138 E

ATOM 15305 CB PROE112 47613 -4524-27613 1004832 E ATOM 15390 CA LYS E 123 72391 7925-12873 1006223 E

ATOM 15306 CG PRO E 112 46357 -4036-28287 1004945 E ATOM 15391 CB LYS E 123 73869 8271 -12755 1008187 E

ATOM 15307 C PRO E 112 47187 -3227-25509 1005382 E ATOM 15392 CG LYS E 123 74753 7054-12588 1007803 E

ATOM 15308 O PRO E 112 46196 -2507-25535 1005395 E ATOM 15393 CD LYS E 123 76201 7447-12408 1007570 E

ATOM 15309 N ILEE 113 48321 -2877-24914 1005933 E ATOM 15394 CE LYS E 123 77070 6223-12215 1007743 E

ATOM 15310 CA ILE E 113 48482 -1574-24279 1006130 E ATOM 15395 NZ LYSE123 78489 6603-11951 1008144 E

ATOM 15311 CB ILEE113 48297 -1633-22764 1004474 E ATOM 15396 C LYSE123 71979 7058-11681 1006305 E

ATOM 15312 CG2 ILE E 113 48516 -0241-22191 1004076 E ATOM 15397 O LYS E 123 71975 7519-10546 1006781 E

ATOM 15313 CGl ILEE 113 46900 -2140-22412 1004180 E ATOM 15398 N GLYE124 71609 5811 -11941 1004681 E

ATOM 15314 CDl ILE E 113 46600 -2080-20910 1004228 E ATOM 15399 CA GLY E 124 71210 4927-10867 1004792 E

ATOM 15315 C ILE E 113 49885 -1041-24533 1006552 E ATOM 15400 C GLY E 124 69717 4658-10761 1004933 E

ATOM 153160 ILEE 113 50869 -1726-24264 1006892 E ATOM 15401 O GLY E 124 69300 3744-10040 1005013 E

ATOM 15317 N TYRE114 49976 0180-25048 1004328 E ATOM 15402 N ASP E 125 68901 5435 -11469 1004884 E

ATOM 15318 CA TYRE114 51273 0781 -25324 1004156 E ATOM 15403 CA ASP E 125 67458 5232-11398 1004763 E

ATOM 15319 CB TYRE 114 51368 1241-26789 1003345 E ATOM 15404 CB ASP E 125 66722 6288-12220 1009888 E

ATOM 15320 CG TYRE 114 52757 1671 -27205 1003131 E ATOM 15405 CG ASP E 125 66797 7668-11602 10010434 E

ATOM 15321 CDl TYR E 114 53709 0727 27595 1003560 E ATOM 15406 ODl ASP E 125 67214 7784-10432 10010599 E

ATOM 15322 CEl TYRE 114 55015 1101 -27915 1003517 E ATOM 15407 OD2 ASP E 125 66426 8641 -12289 10010300 E ATOM 15323 CD2 TYR E 114 53141 3016-27149 1003148 E ATOM 15408 C ASP E 125 67055 3838 -11872 1004668 E

ATOM 15324 CE2 TYR E 114 54436 3406-27467 1003581 E ATOM 15409 O ASP E 125 67705 3255 -12743 1004359 E

ATOM 15325 CZ TYRE 114 55376 2438-27851 1003589 E ATOM 15410 N ARG E 126 65982 3312-11284 1006769 E

ATOM 15326 OH TYRE 114 56674 2794-28173 1003539 E ATOM 15411 CA ARG E 126 65460 1995 -11625 1006317 E

ATOM 15327 C TYR E 114 51488 1972-24404 1004140 E ATOM 15412 CB ARG E 126 65326 1135-10370 1008824 E

ATOM 15328 0 TYRE114 50552 2712-24105 1004431 E ATOM 15413 CG ARG E 126 66629 0698 9743 1008673 E

ATOM 15329 N LEUE115 52729 2154-23972 1004947 E ATOM 15414 CD ARGE 126 66369 0046 -8388 1009165 E

ATOM 15330 CA LEU E 115 53095 3238-23072 1004851 E ATOM 15415 NE ARGE 126 67534 -0689 -7903 1009520 E

ATOM 15331 CB LEUE115 53244 2680-21653 1007389 E ATOM 15416 CZ ARG E 126 67893 -1898 -8335 1009843 E

ATOM 15332 CG LEU E 115 52235 3019-20551 1007714 E ATOM 15417 NHl ARG E 126 68975 -2493 -7840 1009810 E

ATOM 15333 CDl LEU E 115 50822 3076-21092 1007552 E ATOM 15418 NH2ARGE126 67161 -2525 -9249 1009662 E ATOM 15334 CD2 LEU E 115 52361 1980-19450 1008044 E ATOM 15419 C ARGE 126 64081 2121 -12278 1006401 E

ATOM 15335 C LEU E 115 54425 3838-23528 1005095 E ATOM 15420 O ARG E 126 63161 2700-11695 1006123 E

ATOM 15336 O LEU E 115 55342 3107 23897 1005348 E ATOM 15421 N LEU E 127 63929 1568-13478 1005763 E

ATOM 15337 N GLY E 116 54543 5159-23498 1004499 E ATOM 15422 CA LEU E 127 62648 1633-14171 1005401 E

ATOM 15338 CA GLYE 116 55793 5763-23916 1003933 E ATOM 15423 CB LEU E 127 62857 2125-15605 1004930 E

ATOM 15339 C GLYE116 55873 7257-23709 1004318 E ATOM 15424 CG LEU E 127 63499 3511 -15693 1004828 E

ATOM 15340 O GLY E 116 54898 7971 -23927 1004206 E ATOM 15425 CDl LEU E 127 63984 3773-17102 1004886 E

ATOM 15341 N GLY E 117 57043 7724-23287 1004089 E ATOM 15426 CD2LEUE127 62497 4562-15263 1004894 E 65251/C766

ATOM 15427 C LEU E 127 61977 0267-14170 1005376 E ATOM 15512 CA LEUE 138 50125-13432-24095 1008727 E ATOM 15428 O LEU E 127 62620 -0755-14403 1004996 E ATOM 15513 CB LEU E 138 49045-13165-25156 1006933 E

ATOM 15429 N SER E 128 60678 0259-13908 1004758 E ATOM 15514 CG LEUE 138 49419-13762-26530 1006545 E

ATOM 15430 CA SER E 128 59909 -0977-13853 1004725 E ATOM 15515 CDl LEU E 138 49850-15216-26371 1006702 E

ATOM 15431 CB SERE 128 59357 -1194 12439 1007327 E ATOM 15516 CD2LEUE138 48256-13663-27495 1006837 E

ATOM 15432 OG SER E 128 60300 -0831 -11446 1007912 E ATOM 15517 C LEU E 138 51487-13132-24703 1 009062 E

ATOM 15433 C SERE128 58734 -0924-14811 1004643 E ATOM 15518 O LEU E 138 51651 -12156-25431 1008977 E

ATOM 154340 SERE128 58081 0111 -14941 1004771 E ATOM 15519 N PHE E 139 52464 -13971 -24392 1 006508 E

ATOM 15435 N ALA E 129 58467 -2042-15472 1005059 E ATOM 15520 CA PHEE 139 53801-13806-24936 1006646 E

ATOM 15436 CA ALA E 129 57342 -2147 -16392 1005156 E ATOM 15521 CB PHEE 139 54815-13626-23803 10010494 E ATOM 15437 CB ALA E 129 57838 -2430-17807 1004959 E ATOM 15522 CG PHE E 139 54633-14580-22660 10010409 E

ATOM 15438 C ALA E 129 56532 -3322-15857 1005033 E ATOM 15523 CDl PHE E 139 55019-14209-21378 10010362

ATOM 15439 O ALAE129 56868 -4484-16108 1005121 t,

ATOM 15440 N GLU E 130 55469 -3022-15113 1005018 E ATOM 1155552244 CCDD22PPHHEEEE113399 54099-15850-22860 10010670

ATOM 15441 CA GLU E 130 54656 -4064-14502 1005115 E E

ATOM 15442 CB GLU E 130 54735 -3921-12985 10011497 E ATOM 15525 CEl FHE E 139 54878-15085-20310 10010826 E

ATOM 15443 CG GLU E 130 56160 -4014-12456 10011451 E ATOM 15526 CE2PHEE139 53953-16734-21802 10010424 E

ATOM 15444 CD GLU E 130 56333 -3389-11081 10012000 E ATOM 15527 CZ PHE E 139 54343-16351 -20522 10010818 E

ATOM 15445 OEl GLU E 130 57451 -3478-10527 10012137 E ATOM 15528 C PHE E 139 54140-15022 -25796 1007049 E

ATOM 15446 OE2 GLU E 130 55360 -2806-10554 10011981 E ATOM 15529 O PHE E 139 55272-15505-25801 1007059 E

ATOM 15447 C GLU E 130 53208 -4099-14947 1004754 E ATOM 15530 N ALA E 140 53135 -15498 -26528 1008182 E ATOM 15448 O GLU E 130 52707 -3146-15533 1004746 E ATOM 15531 CA ALA E 140 53277-16664-27393 1008312 E

ATOM 15449 N ILEE 131 52554 -5231 -14686 1007514 E ATOM 15532 CB ALA E 140 51903-17275-27684 1005626 E

ATOM 15450 CA ILE E 131 51142 -5435 -15018 1007768 E ATOM 15533 C ALA E 140 53979-16354-28703 1008351 E

ATOM 15451 CB ILE E 131 50949 -6401 -16199 1006901 E ATOM 15534 O ALA E 140 54878-17086-29112 1008540 E

ATOM 15452 CG2 ILE E 131 51485 -5774 -17477 1006924 E ATOM 15535 N GLU E 141 53566-15274-29360 10010889 E

ATOM 15453 CGl ILE E 131 51632 7735 15890 1006520 E ATOM 15536 CA GLU E 141 54152-14906-30638 10011207 E

ATOM 15454 CDl ILE E 131 51418 -8780 -16951 1006381 E ATOM 15537 CB GLU E 141 53301-13841 -31337 10017734 E

ATOM 15455 C ILE E 131 50490 -6059-13800 1007957 E ATOM 15538 CG GLU E 141 53762 -13505 -32754 10017734 E

ATOM 15456 0 ILE E 131 51177 -6615-12945 1008029 E ATOM 15539 CD GLU E 141 54870-12463-32796 10017734 E

ATOM 15457 N ASN E 132 49168 -5989 -13728 1006758 E ATOM 15540 OEl GLU E 141 55638-12453 -33778 10017734

ATOM 15458 CA ASN E 132 48459 -6532-12583 1006458 E E ATOM 15459 CB ASN E 132 47284 -5628-12246 1006553 E ATOM 1155554411 OOEE22 GGLLUU EE 114411 54967-11642-31859 10017734

ATOM 15460 CG ASN E 132 46238 -5628-13330 1006423 E E

ATOM 15461 ODl ASN E 132 46567 -5611-14510 1006592 E ATOM 15542 C GLU E 141 55596-14439-30547 10011417 E

ATOM 15462 ND2 ASN E 132 44971 -5647-12942 1006206 E ATOM 15543 O GLU E 141 56508-15228-30775 10011785 E

ATOM 15463 C ASN E 132 47962 -7965-12773 1006223 E ATOM 15544 N SER E 142 55824-13175-30209 1009392 E

ATOM 15464 O ASN E 132 47825 -8702-11802 1006540 E ATOM 15545 CA SER E 142 57196-12689 -30159 1009691 E

ATOM 15465 N ARG E 133 47691 -8363-14014 1006253 E ATOM 15546 CB SERE 142 57854-12912-31516 1005533 E

ATOM 15466 CA ARG E 133 47199 -9714-14289 1005812 E ATOM 15547 OG SER E 142 59261-12796-31434 1005621 E

ATOM 15467 CB ARG E 133 45804 -9645 -14926 1007131 E ATOM 15548 C SER E 142 57327-11217-29786 1009823 E

ATOM 15468 CG ARG E 133 44743 -9004-14049 1007389 E ATOM 15549 O SER E 142 57666 -10878 -28644 10010332 E

ATOM 15469 CD ARG E 133 44623 -9735 -12712 1007913 E ATOM 15550 N GLY E 143 57091 -10338-30756 1004978 E

ATOM 15470 NE ARGE 133 44266-11144-12875 1007699 E ATOM 15551 CA GLYE 143 57193 -8923-30458 1004725 E

ATOM 15471 CZ ARG E 133 43069 -11578 -13258 1007809 E ATOM 15552 C GLY E 143 55906 -8378 -29863 1004532 E ATOM 15472 NHl ARG E 133 42848 12880 13382 1008077 E ATOM 15553 O GLY E 143 55525 -7253-30177 1004731 E ATOM 15473 NH2ARGE133 42093-10712-13508 1007738 E ATOM 15554 N GLN E 144 55251 -9161-29000 1005501 E

ATOM 15474 C ARG E 133 48121-10533-15190 1006271 E ATOM 15555 CA GLN E 144 53987 -8764 -28377 1004954 E

ATOM 15475 O ARG E 133 47764-10850-16322 1006507 E ATOM 15556 CB GLN E 144 53058 -9971 -28258 1009187 E

ATOM 15476 N PRO E 134 49310-10906-14689 1006772 E ATOM 15557 CG GLN E 144 52955-10805-29516 1009115 E

ATOM 15477 CD PRO E 134 49789-10733-13310 1008754 E ATOM 15558 CD GLN E 144 51918-11911-29398 1009112 E

ATOM 15478 CA PRO E 134 50271 -11693 -15466 1007144 E ATOM 15559 OEl GLN E 144 51906 -12669 -28428 1009669 E

ATOM 15479 CB PRO E 134 51444-11858-14503 1009026 E ATOM 15560 NE2GLNE144 51047 -12014 -30396 1008966 E

ATOM 15480 CG PRO E 134 50778-11875-13180 1009226 E ATOM 15561 C GLN E 144 54149 -8138-26996 1005134 E

ATOM 15481 C PRO E 134 49715-13032-15932 1007662 E ATOM 15562 O GLN E 144 53271 -7419-26529 1005365 E

ATOM 15482 O PRO E 134 50320-13709-16756 1007966 E ATOM 15563 N VAL E 145 55270 -8415 26340 1004100 E

ATOM 15483 N ASP E 135 48564-13421 -15404 1008775 E ATOM 15564 CA VAL E 145 55531 -7884-25009 1003925 E

ATOM 15484 CA ASP E 135 47963 -14681 -15807 1008421 E ATOM 15565 CB VAL E 145 55288 -8962 -23934 1004003 E

ATOM 15485 CB ASPE135 46963-15147-14744 10010110 E ATOM 15566 CGl VAL E 145 55547 -8401 -22559 1003819 E

ATOM 15486 CG ASP E 135 46101-14019-14219 10010057 E ATOM 15567 CG2 VAL E 145 53871 -9467-24025 1003711 E

ATOM 15487 ODl ASP E 135 45183 -13579 -14942 100 "651 E ATOM 15568 C VAL E 145 56977 -7416-24925 1004036 E

ATOM 15488 OD2 ASP E 135 46349-13566-13081 10010215 E ATOM 15569 O VAL E 145 57905 -8220 -24991 1004304 E

ATOM 15489 C ASP E 135 47291 -14554 -17177 I 008292 E ATOM 15570 N TYR E 146 57169 -6110-24786 1004574 E

ATOM 15490 0 ASP E 135 46931 -15557-17793 1008961 E ATOM 15571 CA TYR E 146 58508 -5555 -24699 1004395 E

ATOM 15491 N TYR E 136 47138-13319 17651 1006864 E ATOM 15572 CB TYR E 146 59048 -5215 -26100 1004895 E

ATOM 15492 CA TYR E 136 46524 -13059 -18955 1006985 E ATOM 15573 CG TYR E 146 58102 -4422-26958 1004898 E ATOM 15493 CB TYRE136 45484-11943-18848 1008401 E ATOM 15574 CDl TYR E 146 57108 -5056-27703 1004837 E

ATOM 15494 CG TYRE 136 44183 12338-18196 1008362 E ATOM 15575 CEl TYR E 146 56191 -4325-28462 1004716 E

ATOM 15495 CDl TYRE 136 43731 -11680-17056 1008322 E ATOM 15576 CD2 TYR E 146 58166 -3028-26993 1004457 E

ATOM 15496 CEl TYR E 136 42510-11994-16475 1008577 E ATOM 15577 CE2TYRE146 57252 -2280 -27747 1004662 E

ATOM 15497 CD2 TYR E 136 43377 -13334 -18744 1008579 E ATOM 15578 CZ TYR E 146 56265 -2936 -28477 1004666 E

ATOM 15498 CE2TYRE 136 42151-13658-18169 1008526 E ATOM 15579 OH TYR E 146 55347 -2206 -29202 1004764 E

ATOM 15499 CZ TYRE 136 41725-12979-17033 1008656 E ATOM 15580 C TYR E 146 58566 -4324 -23802 1004226 E

ATOM 15500 OH TYRE136 40512-13280-16457 1009040 E ATOM 15581 O TYR E 146 57543 -3723 -23455 1004043 E

ATOM 15501 C TYR E 136 47575-12650-19990 1007176 E ATOM 15582 N PHE E 147 59790 3956 -23451 1004738 E

ATOM 15502 O TYRE136 47251 -12318-21127 1007464 E ATOM 15583 CA PHE E 147 60052 -2832 -22577 1004690 E

ATOM 15503 N LEU E 137 48835-12681 -19587 1008904 E ATOM 15584 CB PHE E 147 60005 -3352 -21140 1005999 E ATOM 15504 CA LEU E 137 49926-12298-20466 1008575 E ATOM 15585 CG PHE E 147 60500 -2388 -20102 1005904 E

ATOM 15505 CB LEU E 137 51233-12297-19686 1007793 E ATOM 15586 CDl PHE E 147 60238 -1025-20197 1005953 E

ATOM 15506 CG LEU E 137 51985-10979-19593 1007566 E ATOM 15587 CD2 PHE E 147 61 169 -2864-18974 1006137 E

ATOM 15507 CDl LEU E 137 53355-11252-19013 1007780 E ATOM 15588 CEl PHE E 147 60632 -0155-19177 1005986 E

ATOM 15508 CD2LEUE137 52118-10350-20959 1007942 E ATOM 15589 CE2 PHE E 147 61563 -2003 -17954 1005994 E

ATOM 15509 C LEUE137 50107-13197-21679 1008512 E ATOM 15590 CZ PHE E 147 61292 -0646 -18056 1006078 E

ATOM 15510 O LEUE137 50424 14376-21531 1008397 E ATOM 15591 C PHE E 147 61439 -2316 -22954 1004844 E

ATOM 15511 N LEU E 138 49922-12647-22879 1008947 E ATOM 15592 O PHE E 147 62391 -3093-23041 1004592 E 65251/C766

ATOM 15593 N GLY E 148 61558 -1015-23204 1003234 E ATOM 15678 N TYR E 159 78993 -30753 -39741 1004145 E ATOM 15594 CA GLY E 148 62856 -0487 -23577 1003682 E ATOM 15679 CA TYR E 159 79029-31353-41071 1004145 E

ATOM 15595 C GLY E 148 63056 0982 -23264 1003904 E ATOM 15680 CB TYR E 159 78754-30331-42162 1002766 E

ATOM 15596 0 GLY E 148 62123 1689-22884 1004165 E ATOM 15681 CG TYR E 159 77378 -29704 -42147 1003122 E

ATOM 15597 N ILE E 149 64299 1427 23407 1003846 E ATOM 15682 CDl TYR E 159 77084 -28632 -41308 1003122 E

ATOM 15598 CA ILEE 149 64652 2818-23186 1003687 E ATOM 15683 CEl TYR E 159 75846-27993-41360 1003122 E

ATOM 15599 CB ILE E 149 64980 3127-21705 1004798 E ATOM 15684 CD2TYRE159 76391 -3013343034 1003122 E

ATOM 15600 CG2ILEE149 63868 2603-20798 1004853 E ATOM 15685 CE2TYRE159 75148 -29503 -43094 1003122 E

ATOM 15601 CGl ILE E 149 66295 2470-21301 1004402 E ATOM 15686 CZ TYR E 159 74883 -28428 -42255 1003122 E

ATOM 15602 CDl ILE E 149 66715 2859-19929 1004727 E ATOM 15687 OH TYR E 159 73668 -27774 -42325 1003122 E ATOM 15603 C ILEE 149 65874 3144-24025 1003891 E ATOM 15688 C TYRE 159 SO 435-31856^1267 1004145 E

ATOM 156040 ILE E 149 66723 2285-24271 1004408 E ATOM 15689 O TYR E 159 81379 31103 41080 1004145 E

ATOM 15605 N [LE E 150 65951 4391-24463 1005005 E ATOM 15690 N THR E 160 80591-3311541652 1003646 E

ATOM 15606 CA ILE E 150 67057 4861-25278 1005056 E ATOM 15691 CA THR E 160 81930 -33656 -41858 1003646 E

ATOM 15607 CB ILE E 150 66651 4888-26789 1004112 E ATOM 15692 CB THR E 160 82382 -34441 -40627 1004953 E

ATOM 15608 CG2 ILE E 150 65385 5704-26981 1004442 E ATOM 15693 OGl THR E 160 82235-33617-39469 1003687 E

ATOM 15609 CGl ILE E 150 67773 5474-27647 1003911 E ATOM 15694 CG2THRE160 83832 -34851 -40757 1003687 E

ATOM 15610 CDl ILEE 150 68986 4595-27771 1003712 E ATOM 15695 C THR E 160 82124 -34560 -43074 I 003646 E

ATOM 15611 C ILEE 150 67404 6269-24786 1005190 E ATOM 15696 O THR E 160 81390-3552543249 1003646 E

ATOM 15612 0 ILEE150 66520 7080-24512 1005101 E ATOM 15697 N VAL E 161 83098 -34239 -43926 1004576 E

ATOM 15613 N ALAE 151 68692 6548-24650 1006156 E ATOM 15698 CA VAL E 161 83408 -35102 -45067 1004576 E ATOM 15614 CA ALA E 151 69126 7858-24191 1006030 E ATOM 15699 CB VAL E 161 83400 -34364 -46425 1006173 E

ATOM 15615 CB ALA E 151 70527 7767-23603 1003499 E ATOM 15700 CGl VAL E 161 82132-33583-46581 1004624 E

ATOM 15616 C ALAE151 69110 8853 25343 1006126 E ATOM 15701 CG2 VALE 161 84587 -33474 -46544 1004624 E

ATOM 15617 0 ALA E 151 69768 8645-26361 1006364 E ATOM 15702 C VALE 161 84807 -35654 -44799 1004576 E

ATOM 15618 N LEUE152 68363 9938-25178 1007647 E ATOM 15703 O VAL E 161 85699 -34918 -44374 1004576 E

ATOM 15619 CA LEU E 152 68277 10948-26217 1008045 E ATOM 15704 N THR E 162 84985-36952-45027 1005173 E

ATOM 15620 CB LEU E 152 66824 11367 -26413 1007216 E ATOM 15705 CA THR E 162 86258-37610-44773 1005173 E

ATOM 15621 CG LEU E 152 65903 10225-26846 1007341 E ATOM 15706 CB THR E 162 86114-38635-43623 1009439 E

ATOM 15622 CDl LEU E 152 64479 10723-26959 10071 10 E ATOM 15707 OGl THR E 162 85163 -38150 -42668 1006572 E

ATOM 15623 CD2LEUE152 66374 9663-28174 1007261 E ATOM 15708 CG2THRE162 87446 38847 -42920 1006572 E

ATOM 15624 C LEU E 152 69127 12156 -25873 1008330 E ATOM 15709 C THR E 162 86753 -3834846009 1005173 E ATOM 15625 O LEU E 152 70152 12398-26510 1008916 E ATOM 15710 O THR E 162 85958 -38817 -46818 1005173 E

ATOM 15626 N 1LEE153 71405-23865-22438 1004646 E ATOM 15711 N LEU E 163 88069-38448-46162 1004809 E

ATOM 15627 CA ILE E 153 71072 -24718 -23567 1004646 E ATOM 15712 CA LEU E 163 88542 -39172 -47287 1004809 E

ATOM 15628 CB ILE E 153 69640-24474-24052 1004567 E ATOM 15713 CB LEU E 163 90082-38752-47511 1009609 E

ATOM 15629 CG2 ILE E 153 68655-24990-23024 1004245 E ATOM 15714 CG LEUE 163 90333-38219-48919 1004418 E

ATOM 15630 CGl ILEE 153 69433-22985-24335 1004245 E ATOM 15715 CDl LEU E 163 91828-38039-49123 1004418 E

ATOM 15631 CDl ILE E 153 68033-22661-24826 1004245 E ATOM 15716 CD2LEUE163 89778-39170-49953 1004418 E

ATOM 15632 C ILE E 153 72020-24526-24738 1004646 E ATOM 15717 C LEU E 163 88593 -40679 -47010 1004809 E

ATOM 15633 O ILEE 153 72642-23478-24893 1004646 E ATOM 15718 O LEU E 163 8887641512 -47894 1004809 E

ATOM 15634 N THR E 154 72082-25548-25583 1005631 E ATOM 15719 N LYS E 164 88205 -41030 -45783 10020084 E

ATOM 15635 CA THR E 154 72983-25563-26715 1005631 E ATOM 15720 CA LYS E 164 88116-42431-45385 10020084 E

ATOM 15636 CB THR E 154 74257-26352-26321 1004226 E ATOM 15721 CB LYS E 164 8690143099-46039 10011006 E ATOM 15637 OGl THRE 154 75306-25429-26022 1005254 E ATOM 15722 CG LYS E 164 85723-4329445095 10010981 E ATOM 15638 CG2 THR E 154 74694 -27327 -27426 1005254 E ATOM 15723 CD LYS E 164 8609344218-43938 10010981 E

ATOM 15639 C THR E 154 72401 -26181 -27975 1005631 E ATOM 15724 CE LYS E 164 849284444042977 10010981 E

ATOM 15640 O THR E 154 71627-27135-27894 1005631 E ATOM 15725 NZ LYS E 164 8526845444-41919 10010981 E

ATOM 15641 N LEU E 155 72774-25625-29132 1004126 E ATOM 15726 C LYS E 164 893834312945838 10020084 E

ATOM 15642 CA LEU E 155 72361 -26154 -30434 1004126 E ATOM 15727 O LYS E 164 903944247246086 10020084 E

ATOM 15643 CB LEUE 155 71312-25268-31100 1004216 E ATOM 15728 N ASP E 165 893414445345939 10013008 E

ATOM 15644 CG LEUE 155 70783-25845-32431 1003874 E ATOM 15729 CA ASP E 165 90511-4518746400 10013008 E

ATOM 15645 CDl LEU E 155 70245-27246-32209 1003874 E ATOM 15730 CB ASP E 165 902514670646342 10014069 E

ATOM 15646 CD2 LEU E 155 69684 -24957 -33010 1003874 E ATOM 15731 CG ASP E 165 889274710946982 10014069 E

ATOM 15647 C LEU E 155 73619-26227-31300 1004126 E ATOM 15732 ODI ASPE 165 887724694248210 10014069

ATOM 15648 O LEU E 155 74232 -25209 -3160S 1004126 E E

ATOM 15649 N LYSE156 74020-27438-31675 1003844 E ATOM 1155773333 OODD22AASSPPEE116655 880394760046254 10014069

ATOM 15650 CA LYS E 156 75223 -27612 -32478 1003844 E E

ATOM 15651 CB LYSE156 76304-28310-31655 1004439 E ATOM 15734 C ASP E 165 907874471847835 10013008 E

ATOM 15652 CG LYS E 156 77621-28427-32398 1004658 E ATOM 15735 O ASPE 165 907684352448127 10013008 E

ATOM 15653 CD LYS E 156 78732 -29074 -31568 1004658 E ATOM 15736 N ASPE 166 9103245642 -48742 1007053 E

ATOM 15654 CE LYS E 156 78504-30571 -31368 1004658 E ATOM 15737 CA ASP E 166 9128745247-50109 1007053 E

ATOM 15655 NZ LYSE156 79670-31249-30716 1004658 E ATOM 15738 CB ASP E 166 9234346149-50695 10020084 E

ATOM 15656 C LYS E 156 75012-28394-33773 1003844 E ATOM 15739 CG ASP E 166 936744600149993 10020084 E

ATOM 15657 O LYS E 156 74389 29449-33757 1003844 E ATOM 15740 ODl ASP E 166 937564628048778 10020084

ATOM 15658 N TYR E 157 75532-27858-34882 1004073 E E ATOM 15659 CA TYRE 157 75464-28486-36207 1004073 E ATOM 1155774411 OODD22AASSPPEE116666 9464345610-50669 10020084

ATOM 15660 CB TYR E 157 74870 -27523 -37237 1005649 E E

ATOM 15661 CG TYRE 157 73365-27358-37153 1003883 E ATOM 15742 C ASP E 166 9004945235 -51007 1007053 E ATOM 15662 CDl TYR E 157 72634-27913-36106 1003883 E ATOM 15743 O ASP E 166 8936846249 -51201 1007053 E

ATOM 15663 CEl TYR E 157 71253 -27737 -36014 1003883 E ATOM 15744 N GLY E 167 89759 -44060 -51548 1007993 E ATOM 15664 CD2 TYR E 157 72670 -26622 -38113 1003883 E ATOM 15745 CA GLY E 167 8862043928 -52428 1007993 E

ATOM 15665 CE2TYRE157 71295-26447-38031 1003883 E ATOM 15746 C GLY E 167 8773542685 -52335 1007993 E

ATOM 15666 CZ TYRE 157 70592-27006-36979 1003883 E ATOM 15747 O GLY E 167 8815941547 -52554 1007993 E

ATOM 15667 OH TYR E 157 69227 -26840 -36875 1003883 E ATOM 15748 N LEU E 168 8647242944 -52019 1007408 E

ATOM 15668 C TYR E 157 76894-28868-36621 1004073 E ATOM 15749 CA LEU E 168 85434 -41940 -51922 1007408 E

ATOM 15669 0 TYR E 157 77807-28036-36593 1004073 E ATOM 15750 CB LEU E 168 8408142653 -51917 1008783 E ATOM 15670 N ASN E 158 77087-30126-36999 1003720 E ATOM 15751 CG LEU E 168 8409443990 -52670 1008783 E

ATOM 15671 CA ASN E 158 78401 -30623 -37384 1003720 E ATOM 15752 CDl LEU E 168 8276144717 -52490 1008783 E

ATOM 15672 CB ASN E 158 78905 -31599 -36309 1003373 E ATOM 15753 CD2LEUE168 8440043733 -54142 1008783 E

ATOM 15673 CG ASNE158 80301-32150-36599 1004443 E ATOM 15754 C LEU E 168 8554241044 -50704 1007408 E ATOM 15674 ODl ASN E 158 80898 -31846 -37639 1004443 E ATOM 15755 O LEUE 168 863794124949826 1007408 E ATOM 15675 ND2 ASN E 158 80812 -32964 -35671 1004443 E ATOM 15756 N TYR E 169 8467640039 -50670 1005443 E

ATOM 15676 C ASN E 158 78331 -31324 -38736 1003720 E ATOM 15757 CA TYR E 169 84622 -3910449564 1005443 E

ATOM 156770 ASN E 158 77663-32353-38871 1003720 E ATOM 15758 CB TYR E 169 84635 -37662 50077 1006342 E 65251/C766

ATOM 15759 CG TYR E 169 85941-37217-50669 1006342 E ATOM 15844 ODl ASN E 178 71158 -28041 -24138 1005350 E ATOM 15760 CDl TYRE 169 86304-37587-51953 1006342 E ATOM 15845 ND2ASNE178 69693 -29399 -23104 1005350 E

ATOM 15761 CE1TYRE169 87514-37176-52506 1006342 E ATOM 15846 C ASN E 178 73227 -31268 -25942 1004478 E

ATOM 15762 CD2 TYR E 169 86821 -36421 -49936 1006342 E ATOM 15847 O ASN E 178 73860 -31277 -26992 I 004478 E

ATOM 15763 CE2TYRE169 88037-36003-50474 1006342 E ATOM 15848 N ASP E 179 73171 -32316-25131 1004857 E

ATOM 15764 CZ TYR E 169 88379 -36384 -51764 1006342 E ATOM 15849 CA ASP E 179 73878 -33546 -25472 1004857 E

ATOM 15765 OH TYRE 169 89585-35972-52304 1006342 E ATOM 15850 CB ASP E 179 74527 -34173 -242271004285 E

ATOM 15766 C TYR E 169 83321-39352-48823 1005443 E ATOM 15851 CG ASP E 179 73540 -34433 -23104 1004680 E

ATOM 15767 0 TYR E 169 82257-39266-49420 1005443 E ATOM 15852 ODl ASP E 179 72337 -34151 -23283 1004680 E

ATOM 15768 N ASP E 170 83392-39677-47538 1004519 E ATOM 15853 OD2ASPE179 73973 -34921 -22033 1004680 E ATOM 15769 CA ASP E 170 82169 -39891 -46778 1004519 E ATOM 15854 C ASP E 179 72952-34557-26148 1004857 E

ATOM 15770 CB ASP E 170 82403 -40868 -45624 1008211 E ATOM 15855 O ASP E 179 73295 -35720 -26278 1004857 E

ATOM 15771 CG ASP E 170 82087-42292-46003 1008211 E ATOM 15856 N GLN E 180 71787-34096-26593 1003771 E

ATOM 15772 ODl ASP E 170 81107 -42494 -46747 1008211 E ATOM 15857 CA GLN E 180 70810-34947-27258 1003771 E

ATOM 15773 OD2ASPE170 82800-43208 45551 1008211 E ATOM 15858 CB GLN E 180 69400 -34500 -26886 1005882 E

ATOM 15774 C ASP E 170 81659-38566-46229 1004519 E ATOM 15859 CG GLN E 180 69125 -34434 -25416 1005045 E

ATOM 15775 O ASP E 170 82426-37623-46046 1004519 E ATOM 15860 CD GLN E 180 69337 -35759 -24742 1005045 E

ATOM 15776 N GLY E 171 80359-38493-45982 1003437 E ATOM 15861 OEl GLN E 180 70362 -35980 -24119 1005045 E

ATOM 15777 CA GLY E 171 79787-37281 -45432 1003437 E ATOM 15862 NE2 GLN E 180 68371 -36656 24873 1005045 E

ATOM 15778 C GLY E 171 78776-37584^*4341 1003437 E ATOM 15863 C GLN E 180 70901 -34959-28795 1003771 E

ATOM 15779 O GLY E 171 77956-38486-44489 1003437 E ATOM 15864 O GLN E 180 70730 -33928 -29454 1003771 E ATOM 15780 N VALE 172 78859-36865-43228 1004671 E ATOM 15865 N LEU E 181 71149 36127 29372 1003470 E

ATOM 15781 CA VAL E 172 77907-37027-42142 1004671 E ATOM 15866 CA LEUE 181 71190 -36227 -30826 1003470 E

ATOM 15782 CB VAL E 172 78452-37840-40958 1004930 E ATOM 15867 CB LEUE 181 71676-37610-31255 1004514 E

ATOM 15783 CGl VALE 172 78262-39291-41215 1004131 E ATOM 15868 CG LEUE 181 71624 37843 -32762 1003257 E

ATOM 15784 CG2 VAL E 172 79909 -37505 -40710 1004131 E ATOM 15869 CDI LEU E 181 72530 -36867 -33474 1003257 E

ATOM 15785 C VALE 172 77526-35673-41587 1004671 E ATOM 15870 CD2LEUE181 72032-39275-33071 1003257 E

ATOM 15786 O VALE172 78272-34699-41699 1004671 E ATOM 15871 C LEU E 181 69773-35978-31359 1003470 E

ATOM 15787 N PHEE173 76356-35631 -40971 1003614 E ATOM 15872 O LEU E 181 68805 -36561 -30866 1003470 E

ATOM 15788 CA PHE E 173 75860-34425-40360 1003614 E ATOM 15873 N VALE 182 69656 -35103 -32353 1004056 E

ATOM 15789 CB PHE E 173 74841 -33757 -41261 1006196 E ATOM 15874 CA VAL E 182 68356 -34785 -32923 1004056 E

ATOM 15790 CG PHE E 173 74079 -32688 -40574 1004378 E ATOM 15875 CB VAL E 182 68119 -33276 -32960 1005647 E ATOM 15791 CDl PHE E 173 74665-31446-40338 1004378 E ATOM 15876 CGl VAL E 182 66784 -32972 -33606 1003495 E

ATOM 15792 CD2 PHE E 173 72805 -32948 -40069 1004378 E ATOM 15877 CG2 VALE182 68158-32726-31545 1003495 E

ATOM 15793 CEl PHE E 173 73995-30481-39605 1004378 E ATOM 15878 C VALE 182 68231 -35317-34326 1004056 E

ATOM 15794 CE2 PHE E 173 72122 -31990 -39328 1004378 E ATOM 15879 O VALE 182 67180-35822-34715 1004056 E

ATOM 15795 CZ PHE E 173 72717-30754-39094 1004378 E ATOM 15880 N THR E 183 69314-35215-35084 1005113 E

ATOM 15796 C PHE E 173 75197-34796-39033 1003614 E ATOM 15881 CA THR E 183 69320 -35683 -36457 1005113 E

ATOM 15797 O PHE E 173 74497-35808-38939 1003614 E ATOM 15882 CB THR E 183 68909-34562-37412 1005844 E

ATOM 15798 N TYRE174 75434-33998-37997 1003921 E ATOM 15883 OGl THR E 183 67556-34188-37152 1004503 E

ATOM 15799 CA TYR E 174 74822 -34263 -36702 1003921 E ATOM 15884 CG2THRE183 69063 -35009 -38858 1004503 E

ATOM 15800 CB TYR E 174 75847 -34745 -35676 1005679 E ATOM 15885 C THRE 183 70681 36168-36915 1005113 E

ATOM 15801 CG TYR E 174 76429-36104-35960 1004283 E ATOM 15886 O THR E 183 71711 -35586-36576 1005113 E

ATOM 15802 CDl TYR E 174 77726-36238-36456 1004283 E ATOM 15887 N LYS E 184 70688-37248-37681 1004530 E

ATOM 15803 CE1TYRE174 78275-37489-36708 1004283 E ATOM 15888 CA LYS E 184 71926 -37745 -38254 1004530 E

ATOM 15804 CD2 TYR E 174 75688 -37266 -35724 1004283 E ATOM 15889 CB LYS E 184 72352 -39077 -37667 1004940 E

ATOM 15805 CE2 TYR E 174 76226 -38528 -35975 1004283 E ATOM 15890 CG LYS E 184 73614-39577-38331 1004124 E

ATOM 15806 CZ TYR E 174 77523 -38632 -36468 1004283 E ATOM 15891 CD LYS E 184 74044 -40935 -37835 1004124 E

ATOM 15807 OH TYR E 174 78084 -39871 -36726 1004283 E ATOM 15892 CE LYS E 184 75281 -41420 -38575 1004124 E

ATOM 15808 C TYR E 174 74189-32988-36186 1003921 E ATOM 15893 NZ LYS E 184 75634-42817-38193 1004124 E

ATOM 15809 0 TYR E 174 74762-31903-36302 1003921 E ATOM 15894 C LYS E 184 71655 -37930 -39735 1004530 E

ATOM 15810 N ASP E 175 72995-33133-35627 1005447 E ATOM 15895 O LYS E 184 70620 -38459 -40127 1004530 E

ATOM 15811 CA ASPE175 72253-32023-35053 1005447 E ATOM 15896 N ILE E 185 72576-37470 -40559 1004504 E

ATOM 15812 CB ASPE175 70864-31929-35689 1006656 E ATOM 15897 CA ILE E 185 72429 -37601 -41994 1004504 E

ATOM 15813 CG ASP E 175 70073-30724-35205 1005477 E ATOM 15898 CB ILE E 185 72028-36253-42634 1005171 E

ATOM 15814 ODl ASP E 175 70261 30309 34042 1005477 E ATOM 15899 CG2ILEE185 72191 -36312 -44128 1002063 E

ATOM 15815 OD2 ASP E 175 69245 -30199 -35987 1005477 E ATOM 15900 CGl ILE E 185 70574-35928-42305 1002063 E

ATOM 15816 C ASP E 175 72127-32391 -33577 1005447 E ATOM 15901 CDl ILE E 185 70156 -34517 -42704 1002063 E

ATOM 15817 O ASP E 175 71485 33383-33235 1005447 E ATOM 15902 C ILE E 185 73765 -38050 -42558 1004504 E

ATOM 15818 N HIS E 176 72750-31607-32703 1006267 E ATOM 15903 O ILE E 185 74825 -37596 -42114 1004504 E

ATOM 15819 CA HIS E 176 72696-31876-31271 1006267 E ATOM 15904 N SER E 186 73724-38964-43517 1004581 E

ATOM 15820 CB HIS E 176 74102 -32127 -30727 1008470 E ATOM 15905 CA SER E 186 74958-39422-44138 1004581 E

ATOM 15821 CG HIS E 176 74663-33471 -31068 1005383 E ATOM 15906 CB SER E 186 75396 -40763 -43545 1007956 E

ATOM 15822 CD2 HIS E 176 75650-33839-31921 1005383 E ATOM 15907 OG SERE 186 74299 ^l 637 -43419 1006867 E

ATOM 15823 NDl HIS E 176 74219-34633-30474 1005383 E ATOM 15908 C SER E 186 74802-39494-45653 1004581 E

ATOM 15824 CEl HIS E 176 74908-35659-30943 1005383 E ATOM 15909 O SER E 186 73702 39650 -46172 1004581 E ATOM 15825 NE2 HIS E 176 75783-35205-31822 1005383 E ATOM 15910 N TYR E 187 75911 -39333-46357 1005204 E

ATOM 15826 C HIS E 176 72091-30736-30476 1006267 E ATOM 15911 CA TYRE 187 75908 -39353 -47804 1005204 E

ATOM 15827 O HIS E 176 72537-29592-30586 1006267 E ATOM 15912 CB TYRE 187 77178-38712-48325 1009060 E

ATOM 15828 N TYR E 177 71065-31045-29690 1004270 E ATOM 15913 CG TYRE 187 77186-38590-49811 1004481 E

ATOM 15829 CA TYR E 177 70459 -30054 -28804 1004270 E ATOM 15914 CDl TYR E 187 76368-37659-50451 1004481 E

ATOM 15830 CB TYRE177 68946-30167-28790 1004961 E ATOM 15915 CEl TYR E 187 76383-37516-51823 1004481 E

ATOM 15831 CG TYR E 177 68331-29215-27802 1004262 E ATOM 15916 CD2TYRE187 78021 -39395 -50588 1004481 E

ATOM 15832 CDl TYR E 177 68381 -27840-28010 1004262 E ATOM 15917 CE2TYRE187 78044-39264-51975 1004481 E

ATOM 15833 CEl TYR E 177 67861 26952-27078 1004262 E ATOM 15918 CZ TYR E 187 77222-38314-52583 1004481 E

ATOM 15834 CD2 TYR E 177 67741 -29683 -26631 1004262 E ATOM 15919 OH TYRE 187 77270-38138-53946 1004481 E

ATOM 15835 CE2 TYR E 177 67221 -28810-25695 1004262 E ATOM 15920 C TYR E 187 75822 -40769 -48334 1005204 E ATOM 15836 CZ TYRE 177 67281-27440-25923 1004262 E ATOM 15921 O TYR E 187 76688 -41601 -48049 1005204 E

ATOM 15837 OH TYR E 177 66751 -26566 -25000 1004262 E ATOM 15922 N ASN E 188 74774 -41035 -49107 1005472 E

ATOM 15838 C TYR E 177 71020 30483 -27450 1004270 E ATOM 15923 CA ASN E 188 74544^12344-49711 1005472 E

ATOM 15839 O TYR E 177 70726-31583 26998 1004270 E ATOM 15924 CB ASN E 188 73053-42512-49969 10018658 E

ATOM 15840 N ASN E 178 71824-29638-26802 1004478 E ATOM 15925 CG ASN E 188 72713^3848 50563 1004761 E

ATOM 15841 CA ASNE178 72455-30030-25541 1004478 E ATOM 15926 ODl ASN E 188 73269 -44256 -51578 1004761 E

ATOM 15842 CB ASN E 178 71432 -30388 -24460 1006103 E ATOM 15927 ND2ASNE188 71788 -44543 -49936 1004761 E

ATOM 15843 CG ASNE178 70744-29174-23888 1005350 E ATOM 15928 C ASN E 188 75319-42427-51036 1005472 E 65251/C766

ATOM 15929 O ASN E 188 74996-41710-51987 1005472 E ATOM 16014 0 PHEE198 67830-38451 -37558 1004825 E ATOM 15930 N HIS E 189 76328-43300-51 105 1004083 E ATOM 16015 N ARGE199 66399-39572-36257 1004608 E ATOM 15931 CA HIS E 189 77134-43416-52316 1004083 E ATOM 16016 CA ARG E 199 65598-38404-35964 1004608 E ATOM 15932 CB HIS E 189 78397^14198-52006 10010643 E ATOM 16017 CB ARG E 199 64492-38215-36989 1005525 E ATOM 15933 CG HIS E 189 79370-43416-51195 1006697 E ATOM 16018 CG ARG E 199 63625 -37034 -36653 1005525 E ATOM 15934 CD2HISE189 79621 -43409 -49866 1006697 E ATOM 16019 CD ARG E 199 64347-35751 -36969 1005525 E ATOM 15935 NDI HIS E 189 80156 -42425 -51743 1006697 E ATOM 16020 NE ARG E 199 63915-35246-38262 1005525 E ATOM 15936 CEl HIS E 189 80851 -41839 -50786 1006697 E ATOM 16021 CZ ARG E 199 64704 -34627 -39129 1005525 E ATOM 15937 NE2HISE189 80544 -42418 -49637 1006697 E ATOM 16022 NHl ARG E 199 65978 -34437 -38843 1005525 ATOM 15938 C HIS E 189 76416-44003-53516 1004083 E E ATOM 15939 O HIS E 189 76749 -43693 -54665 1004083 E ATOM 16023 NH2 ARG E 199 64214 -34186 -40283 1005525 ATOM 15940 N GLU E 190 75421 -44841 -53245 1004911 E E ATOM 15941 CA GLU E 190 74644 -45479 -54293 I 004911 E ATOM 16024 C ARG E 199 64977-38622-34601 1004608 E ATOM 15942 CB GLU E 190 73784 -46577 -53676 10010431 E ATOM 16025 O ARGE199 64221-39568-34403 1004608 E ATOM 15943 CG GLU E 190 73390 -47679 -54614 1007873 E ATOM 16026 N ALA E 200 65307 -37757 -33654 1005141 E ATOM 15944 CD GLU E 190 72651 -48796 -53899 1007873 E ATOM 16027 CA ALA E 200 64754-37877-32318 1005141 E ATOM 15945 OEl GLU E 190 71539-48536-53387 1007873 E ATOM 16028 CB ALA E 200 65258 -36742 -31443 1003861 E ATOM 15946 OE2GLUE190 73181 -49930-53841 1007873 E ATOM 16029 C ALAE200 63226-37858-32388 1005141 E ATOM 15947 C GLU E 190 73770 -44403 -54940 1004911 E ATOM 16030 0 ALAE200 62629-37066-33127 1005141 E ATOM 15948 O GLU E 190 73840 -44148 56145 1004911 E ATOM 16031 N ASPE201 62606-38741-31612 1007893 E ATOM 15949 N THR E 191 72972 -43742 -54112 1004750 E ATOM 16032 CA ASP E 201 61155-38864-31558 1007893 E ATOM 15950 CA THR E 191 72053 -42691 -54550 1004750 E ATOM 16033 CB ASP E 201 60783-40024-30633 10014771 E ATOM 15951 CB THR E 191 71006 -42443 -53486 1006512 E ATOM 16034 CG ASP E 201 61498-39948-29298 10014771 E ATOM 15952 OGl THRE 191 70235 -43624 -53305 1006512 E ATOM 16035 ODl ASP E 201 62738-40115-29282 10014771 ATOM 15953 CG2THRE191 70093-41351 -53897 1006512 E E ATOM 15954 C THR E 191 72688 -41340 -54883 1004750 E ATOM 16036 OD2 ASP E 201 60827-39711 -28268 10014771 ATOM 15955 O THR E 191 72156 -40579 -55686 1004750 E E ATOM 15956 N ARG E 192 73809^1027 54243 1006152 E ATOM 16037 C ASPE201 60429-37594-31095 1007893 E ATOM 15957 CA ARG E 192 74510 -39776 -54483 1006152 E ATOM 16038 0 ASPE201 59292-37347-31492 1007893 E ATOM 15958 CB ARG E 192 74695-39535-55983 1005152 E ATOM 16039 N TRP E 202 61085-36789-30265 1005492 E ATOM 15959 CG ARG E 192 75617 -40545 -56642 1005152 E ATOM 16040 CA TRP E 202 60464-35574-29741 1005492 E ATOM 15960 CD ARG E 192 76985 -40540 -56005 1005152 E ATOM 16041 CB TRP E 202 61036-35226-28370 1005212 E ATOM 15961 NE ARGE 192 77815-41631-56496 1005152 E ATOM 16042 CG TRP E 202 62529-35126-28315 1005212 E ATOM 15962 CZ ARG E 192 78264 -41735 -57748 1005152 E ATOM 16043 CD2 TRP E 202 63319-33959-28559 1005212 E ATOM 15963 NHl ARG E 192 77966 -40804 -58639 1005152 E ATOM 16044 CE2 TRP E 202 64673-34313-28335 1005212 E ATOM 15964 NH2 ARGE192 79006 -42777 -58118 1005152 E ATOM 16045 CE3 TRP E 202 63017-32651-28944 1005212 E ATOM 15965 C ARG E 192 73866-38558-53841 006152 E ATOM 16046 CDl TRP E 202 63407-36116-27971 1005212 E ATOM 15966 O ARG E 192 73965-37451 -54358 006152 E ATOM 16047 NEl TRP E 202 64697 -35634 -27975 1005212 E ATOM 15967 N HIS E 193 73202-38765-52712 1004386 E ATOM 16048 CZ2 TRP E 202 65720 -33405 -28483 1005212 E ATOM 15968 CA HIS E 193 72601 -37665 -51958 1004386 E ATOM 16049 CZ3 TRP E 202 64058-31748-29091 1005212 E ATOM 15969 CB HIS E 193 71237 -37273 -52539 1006412 E ATOM 16050 CH2 TRP E 202 65396-32132-28860 1005212 E ATOM 15970 CG HIS E 193 70138 -38254 -52270 1006412 E ATOM 16051 C TRP E 202 60561 -34332-30603 1005492 E ATOM 15971 CD2HISE193 70036-39272-51383 1006412 E ATOM 16052 O TRP E 202 59940-33311 -30292 1005492 E ATOM 15972 NDl HIS E 193 68946 -38227 -52954 1006412 E ATOM 16053 N PHEE203 61325-34416-31686 1004916 E ATOM 15973 CEl HIS E 193 68158-39186-52505 1006412 E ATOM 16054 CA PHE E 203 61523-33272-32562 1004916 E ATOM 15974 NE2 HIS E 193 68796-39836-51551 1006412 E ATOM 16055 CB PHE E 203 63006-33187-32944 1005704 E ATOM 15975 C HIS E 193 72494-38116-50501 1004386 E ATOM 16056 CG PHE E 203 63374-31935-33687 1005704 E ATOM 15976 O HIS E 193 72720 -39294 -50204 1004386 E ATOM 16057 CDl PHE E 203 63367-30701-33044 1005704 E ATOM 15977 N GLY E 194 72152-37210-49591 1004975 E ATOM 16058 CD2 PHE E 203 63741 -31988 -35030 1005704 E ATOM 15978 CA GLY E 194 72073 -37589 -48186 1004975 ε ATOM 16059 CEl PHE E 203 63722-29539-33725 1005704 E ATOM 15979 C GLY E 194 70812 -38321 -47762 1004975 E ATOM 16060 CE2 PHE E 203 64097-30826-35720 1005704 E ATOM 15980 O GLY E 194 69803 -38277 -48457 1004975 E ATOM 16061 CZ PHE E 203 64090-29603-35068 1005704 E ATOM 15981 N ASN E 195 70871 39011 ^16627 1004897 E ATOM 16062 C PHEE203 60676-33309-33824 1004916 E ATOM 15982 CA ASN E 195 69716-39734-46093 1004897 ε ATOM 16063 0 PHE E 203 60959-34088-34735 1004916 E ATOM 15983 CB ASN E 195 69824 -41253 -46308 1005687 E ATOM 16064 N ASN E 204 59637 -32476 -33873 1005070 E ATOM 15984 CG ASN E 195 69690 -41661 -47756 1005687 ε ATOM 16065 CA ASN E 204 58791-32387-35062 1005070 E ATOM 15985 ODl ASN E 195 68804-41193-48471 1005687 E ATOM 16066 CB ASN E 204 57332-32057 34695 1008893 E ATOM 15986 ND2ASNE195 70564 -42560 -48194 1005687 E ATOM 16067 CG ASN E 204 56483-31691 -35916 1008893 E ATOM 15987 C ASN E 195 69661 -39489 -44595 1004897 E ATOM 16068 ODl ASN E 204 56713-30660-36541 1008893 E ATOM 15988 O ASN E 195 70700 -39439 -43923 1004897 E ATOM 16069 ND2ASNE204 55540 32552-36286 1008893 E ATOM 15989 N VAL E 196 68457-39333-44063 1004121 E ATOM 16070 C ASN E 204 59416-31251 -35862 1005070 E ATOM 15990 CA VALE 196 68325-39137-42634 1004121 E ATOM 16071 O ASN E 204 59203-30080-35556 1005070 E ATOM 15991 CB VALE 196 66991 -38497 -42254 1003500 E ATOM 16072 N ILE E 205 60205 31591 -36875 1005396 E ATOM 15992 CGl VAL E 196 66896 -38402 -40742 1003500 E ATOM 16073 CA ILE E 205 60879-30576-37678 1005396 E ATOM 15993 CG2VALE196 66872 -37114 -42883 1003500 E ATOM 16074 CB ILE E 205 61740 -31230 -38785 1004386 E ATOM 15994 C VAL E 196 68380-40515-42001 1004121 E ATOM 16075 CG2 ILE E205 60869 -31583 -39975 1004386 E ATOM 15995 O VAL E 196 67530 -41357 -42276 1004121 E ATOM 16076 CGl ILE E 205 62850-30262-39212 1004386 E ATOM 15996 N ASN E 197 69385 -40754 -41163 1006034 E ATOM 16077 CDl ILE E 205 64011 -30933 -39900 1004386 E ATOM 15997 CA ASN E 197 69535-42050-40518 1006034 E ATOM 16078 C ILE E 205 59947 -29534 -38311 1005396 E ATOM 15998 CB ASN E 197 71009 -42392 -40308 1006672 E ATOM 16079 0 ILEE205 60395-28471-38743 1005396 E ATOM 15999 CG ASN E 197 71839-42180-41548 1006672 E ATOM 16080 N SER E 206 58656-29835-38367 1006050 E ATOM 16000 ODl ASN E 197 71467 -42607 -42643 1006672 E ATOM 16081 CA SER E 206 57700-28895-38938 1006050 E ATOM 16001 ND2ASNE197 72985-41518-41383 1006672 E ATOM 16082 CB SER E 206 56389-29598-39277 1006877 E ATOM 16002 C ASN E 197 68854^(2042-39171 1006034 E ATOM 16083 OG SER E 206 56593-30546-40305 1006877 E ATOM 16003 O ASN E 197 68350-43059-38715 1006034 E ATOM 16084 C SER E 206 57429 -27763 -37965 1006050 E ATOM 16004 N PHE E 198 68835-40885-38531 1004825 E ATOM 16085 O SER E 206 56983-26688 38356 1006050 E ATOM 16005 CA PHE E 198 68236-40785-37221 1004825 E ATOM 16086 N ARG E 207 57697-28014-36692 1006148 E ATOM 16006 CB PHE E 198 69324 -40867 -36162 1004087 E ATOM 16087 CA ARG E 207 57488 -27006 -35678 I 006148 E ATOM 16007 CG PHE E 198 68803 -40790 -34760 1004087 E ATOM 16088 CB ARG E 207 57030-27657-34375 1008675 E ATOM 16008 CDl PHEE 198 68473 -41953 -34065 1004087 E ATOM 16089 CG ARG E 207 55592-28133-34411 1008675 E ATOM 16009 CD2PHEE198 68602 -39551 -34140 1004087 E ATOM 16090 CD ARG E 207 54950 -28043 -33040 1008675 E ATOM 16010 CEl PHE E 198 67954 -41892 -32787 1004087 E ATOM 16091 NE ARG E 207 55370-29122-32156 1008675 E ATOM 16011 CE2 PHE E 198 68080-39481-32858 1004087 E ATOM 16092 CZ ARG E 207 55382 -29032 -30827 1008675 E ATOM 16012 CZ PHE E 198 67757 -40653 -32183 1004087 E ATOM 16093 NHl ARG E 207 55001 -27903 -30233 1008675 ATOM 16013 C PHEE 198 67467 -39495 -37030 1004825 E E 65251/C766

ATOM 16094 NH2 ARG E 207 55762 -30073 -30090 1008675 E ATOM 16179 CD2PHEE218 74030 -34624 -47100 1003968 E

ATOM 16095 C ARG E 207 58750 -26183 -35436 1006148 E ATOM 16180 CEl PHEE218 75656 -34679 -44858 1003968 E

ATOM 16096 O ARG E 207 58815-25420 -34472 1006148 E ATOM 16181 CE2PHEE218 75079-35516-47033 1003968 E

ATOM 16097 N SER E 208 59750 -26336 -36305 1005212 E ATOM 16182 CZ PHE E 218 75898 -35544 -45904 1003968 E

ATOM 16098 CA SER E 208 60993-25586-36164 1005212 E ATOM 16183 C PHEE218 73877-31565-48015 1003321 E

ATOM 16099 CB SER E 208 62137-26494-35748 1005656 E ATOM 16184 O PHEE218 75106 31505 ^8115 1003321 E

ATOM 16100 OG SER E 208 63296-25715-35518 1005656 E ATOM 16185 N ASN E 219 73090-31817-49053 1004437 E

ATOM 16101 C SER E 208 61351 -24897-37463 1005212 E ATOM 16186 CA ASN E 219 73683 -32030 -50365 1004437 E

ATOM 16102 O SER E 208 62317-25264-38135 1005212 E ATOM 16187 CB ASN E 219 72604 -32234 -51422 1006310 E

ATOM 16103 N PRO E 209 60571 -23874 -37826 1005181 E ATOM 16188 CG ASNE219 71683 -33393 -51095 1005473 E

ATOM 16104 CD PRO E 209 59508-23354-36951 1005090 E ATOM 16189 ODI ASNE219 72111-34413-50552 1005473 E

ATOM 16105 CA PRO E 209 60694 -23044 -39029 I 005181 E ATOM 16190 ND2ASNE219 70410 -33246 -51437 1005473 E

ATOM 16106 CB PRO E 209 59801 -21848-38712 1005090 E ATOM 16191 C ASNE219 74562 -30852 -50735 1004437 E

ATOM 16107 CG PRO E 209 58739 -22455 -37882 1005090 E ATOM 16192 O ASN E 219 75667-31022-51247 1004437 E

ATOM 16108 C PRO E 209 62108 -22592 -39349 1005181 E ATOM 16193 N PHE E 220 74082 -29648 -50459 1004487 E

ATOM 16109 O PRO E 209 62448-22391 -40515 1005181 E ATOM 16194 CA PHE E 220 74863 -28456 -50766 1004487 E

ATOM 16110 N HIS E 210 62927-22434-38311 1005294 E ATOM 16195 CB PHE E 220 74114 -27198 -50337 1003405 E

ATOM 16111 CA HIS E 210 64279 21950 38504 1005294 E ATOM 16196 CG PHE E 220 74963 -25958 -50346 1002703 E

ATOM 16112 CB HIS E 210 64585-20915-37437 1005619 E ATOM 16197 CDl PHE E 220 75170-25243-51514 1002703 E

ATOM 16113 CG HISE210 63699 -19717 -37524 1005619 E ATOM 16198 CD2 PHE E 220 75615 -25539 -49176 1002703 E

ATOM 16114 CD2HISE210 62665-19318-36750 1005619 E ATOM 16199 CEl PHE E 220 76025-24120-51528 1002703 E

ATOM 16115 NDl HISE210 63792 -18798 -38546 1005619 E ATOM 16200 CE2PHEE220 76466 -24433 -49175 1002703 E

ATOM 16116 CE 1 HIS E 210 62855-17880-38397 1005619 E ATOM 16201 CZ PHE E 220 76672-23720-50361 1002703 E

ATOM 16117 NE2HISE210 62156-18173-37314 1005619 E ATOM 16202 C PHE E 220 76214-28486-50066 1004487 E

ATOM 16118 C HIS E 210 65376 -22990 -38604 1005294 E ATOM 16203 O PHE E 220 77253 28368 50701 1004487 E

ATOM 16119 O HIS E 210 66565 -22653 -38628 1005294 E ATOM 16204 N TRP E 221 76194 -28636 -48748 1004682 E

ATOM 16120 N THR E 211 64975 -24254 -38662 1005828 E ATOM 16205 CA TRP E 221 77428 -28651 -47976 1004682 E

ATOM 16121 CA THR E 211 65944 -25319 -38847 1005828 E ATOM 16206 CB TRP E 221 77111 -28627 -46475 1004192 E

ATOM 16122 CB THR E 211 65440 -26665 -38297 1005098 E ATOM 16207 CG TRP E 221 76621-27300-46005 1003507 E

ATOM 16123 OGl THR E 211 65250 -26563 -36882 1005098 E ATOM 16208 CD2TRPE221 77335 -26060 -46056 1003507 E

ATOM 16124 CG2THRE211 66454 -27764 -38578 1005098 E ATOM 16209 CE2TRPE221 76467 -25057 -45573 1003507 E

ATOM 16125 C THR E 211 66024-25376-40371 1005828 E ATOM 16210 CE3TRPE221 78623 -25698 -46469 1003507 E

ATOM 16126 O THR E 211 65000 -25481 -41043 1005828 E ATOM 16211 CDl TRP E 221 75384-27010-45501 1003507 E

ATOM 16127 N PRO E 212 67236 -25279 -40935 1004874 E ATOM 16212 NEl TRP E 221 75284 -25664 -45240 1003507 E

ATOM 16128 CD PRO E 212 68522 -25252 -40210 1004283 E ATOM 16213 CZ2TRPE221 76847 -23709 -45489 1003507 E

ATOM 16129 CA PRO E 212 67445-25312-42388 1004874 E ATOM 16214 CZ3TRPE221 79002 -24352 -46385 1003507 E

ATOM 16130 CB PRO E 212 68957 -25484 -42505 1004283 E ATOM 16215 CH2TRPE221 78115 -23377 -45899 1003507 E

ATOM 16131 CG PRO E 212 69474-24776-41268 1004283 E ATOM 16216 C TRP E 221 78344 -29825 -48300 1004682 E

ATOM 16132 C PRO E 212 66677 -26412 -43144 1004874 E ATOM 16217 O TRP E 221 79549 -29642 -48502 1004682 E

ATOM 16133 O PRO E 212 66559 27540 42663 1004874 E ATOM 16218 N TYR E 222 77787-31030-48345 1004706 E

ATOM 16134 N GLY E 213 66171 -26072 -44330 1005648 E ATOM 16219 CA TYR E 222 78597 -32196 -48649 1004706 E

ATOM 16135 CA GLY E 213 65436-27021 -45150 1005648 E ATOM 16220 CB TYR E 222 77723-33413-48914 1004664 E

ATOM 16136 C GLY E 213 66353 -27877 -46009 1005648 E ATOM 16221 CG TYR E 222 78529 -34565 -49448 1004521 E

ATOM 16137 O GLY E 213 67572 -27705 -45977 1005648 E ATOM 16222 CDl TYR E 222 79325 -35339 -48604 1004521 E

ATOM 16138 N ASN E 214 65775 -28795 -46781 1008755 E ATOM 16223 CEl TYR E 222 80125 -36347 -49109 1004521 E

ATOM 16139 CA ASN E 214 66551 -29699 -47630 1008755 E ATOM 16224 CD2 TYR E 222 78556-34835-50808 1004521 E

ATOM 16140 CB ASN E 214 67387-28940-48654 1008188 E ATOM 16225 CE2 TYR E 222 79353 35837-51323 1004521 E

ATOM 16141 CG ASN E 214 66665 -27765 -49236 1007605 E ATOM 16226 CZ TYR E 222 80133-36589-50478 1004521 E

ATOM 16142 ODl ASNE214 65451 -27641 -49107 1007605 E ATOM 16227 OH TYR E 222 80928-37570-51024 1004521 E

ATOM 16143 ND2 ASNE214 67409 -26888 -49893 1007605 E ATOM 16228 C TYR E 222 79428 31924-49889 1004706 E

ATOM 16144 C ASNE214 67501 -30484 -46752 1008755 E ATOM 16229 O TYR E 222 80651 -32052 -49889 1004706 E

ATOM 16145 O ASN E 214 68699 -30557 -47034 1008755 E ATOM 16230 N SER E 223 78744 -31538 -50950 1004485 E

ATOM 16146 N ASP E 215 66967 -31068 -45687 1006576 E ATOM 16231 CA SER E 223 79392-31249-52211 1004485 E

ATOM 16147 CA ASP E 215 67783 -31834 -44765 1006576 E ATOM 16232 CB SER E 223 78335 -30893 -53239 1003853 E

ATOM 16148 CB ASPE215 68142-33190-45366 10018320 E ATOM 16233 OG SER E 223 78963 -30479 -54424 1003715 E

ATOM 16149 CG ASP E 215 66921 -33988 -45747 10010458 E ATOM 16234 C SER E 223 80446-30140-52164 1004485 E

ATOM 16150 ODl ASP E 215 66058 -34207 -44870 10010458 E ATOM 16235 O SER E 223 81558-30306-52659 1004485 E

ATOM 16151 OD2ASPE215 66822 -34390 -46925 10010458 E ATOM 16236 N LEU E 224 80093 -29005 -51571 1004365 E

ATOM 16152 C ASPE215 69038-31043 -44467 1006576 E ATOM 16237 CA LEU E 224 81010-27887-51483 1004365 E

ATOM 16153 O ASP E 215 70145 -31459 -44819 1006576 E ATOM 16238 CB LEU E 224 80277-26640-51011 1006690 E

ATOM 16154 N TYRE216 68839-29880-43851 1004040 E ATOM 16239 CG LEU E 224 81171-25404-50895 1004414 E

ATOM 16155 CA TYR E 216 69932 28989 -43448 1004040 E ATOM 16240 CDl LEU E 224 81892-25148-52212 1004414 E

ATOM 16156 CB TYR E 216 70726 -29626 -42305 1006468 E ATOM 16241 CD2 LEU E 224 80325 -24208 -50496 1004414 E

ATOM 16157 CG TYR E 216 69875 -30086-41154 1004343 E ATOM 16242 C LEU E 224 82171 -28184-50556 1004365 E

ATOM 16158 CD1TYRE216 68997 -31166 -41288 1004343 E ATOM 16243 O LEU E 224 83273 -27682 -50758 1004365 E

ATOM 16159 CE1TYRE216 68203-31597-40216 1004343 E ATOM 16244 N MET E 225 81929 28994 -49532 1003846 E

ATOM 16160 CD2TYRE216 69944 -29441 -39921 1004343 E ATOM 16245 CA MET E 225 82995-29346-48613 1003846 E

ATOM 16161 CE2TYRE216 69159-29851-38836 1004343 E ATOM 16246 CB MET E 225 82422 -29925 -47334 1008520 E

ATOM 16162 CZ TYRE216 68292-30931-38991 1004343 E ATOM 16247 CG MET E 225 81684 -28898 -46546 1005392 E

ATOM 16163 OH : TYR E 216 67529 -31335 -37920 1004343 E ATOM 16248 SD MET E 225 81197-29470-44934 1005392 E

ATOM 16164 C TYRE216 70895 -28627 AA 571 1004040 E ATOM 16249 CE MET E 225 82827-29775-44182 1005392 E

ATOM 16165 O TYRE216 72094 -28469 -44337 1004040 E ATOM 16250 C MET E 225 83901 -30361 -49283 1003846 E

ATOM 16166 N ASNE217 70376-28484-45781 1003613 E ATOM 16251 O MET E 225 85112-30349-49093 1003846 E

ATOM 16167 CA ASN E 217 71219-28152-46927 1003613 E ATOM 16252 N LYS E 226 83308 -31244 -50070 1005456 E

ATOM 16168 CB ASN E 217 71746-26720-46801 1004437 E ATOM 16253 CA LYS E 226 84085 -32243 -50772 1005456 E

ATOM 16169 CG ASN E 217 70627-25683-46783 1003910 E ATOM 16254 CB LYS E 226 83172 -33125 -51609 10010467 E

ATOM 16170 ODl ASNE217 70529 -24883 -45852 1003910 E ATOM 16255 CG LYS E 226 83897 -34174 -52392 1005613 E

ATOM 16171 ND2ASNE217 69777 25694 -47822 1003910 E ATOM 16256 CD LYS E 226 82949-34907-53303 1005613 E

ATOM 16172 C ASN E 217 72399 -29118 -47022 1003613 E ATOM 16257 CE LYS E 226 83704-35801-54263 1005613 E

ATOM 16173 O ASN E 217 73498 -28723 -47435 1003613 E ATOM 16258 NZ LYS E 226 82787-36490-55211 1005613 E

ATOM 16174 N PHE E 218 72160 -30379 -46659 1003321 E ATOM 16259 C LYS E 226 85058-31489-51668 1005456 E

ATOM 16175 CA PHE E 218 73210-31367-46666 1003321 E ATOM 16260 O LYS E 226 86248 -31805 -51706 1005456 E

ATOM 16176 CB PHE E 218 72700-32714-46165 1004316 E ATOM 16261 N GLU E 227 84548 -30476 -52369 1005453 E

ATOM 16177 CG PHE E 218 73777 -33744 -46053 1003968 E ATOM 16262 CA GLU E 227 85368 -29660 -53264 1005453 E

ATOM 16178 CDl PHE E 218 74596 -33782 -44936 1003968 E ATOM 16263 CB GLU E 227 84518-28575-53921 10012264 E 65251/C766

ATOM 16264 CG GLU E 227 85271 -27770 -54959 1009844 E ATOM 16349 O SER E 237 100494-28783-44768 1009972 E ATOM 16265 CD GLU E 227 84551 -26494-55350 1009844 E ATOM 16350 N THR E 238 99230 -29428 -46517 10011232 E

ATOM 16266 OEl GLU E 227 83352 -26565 -55708 1009844 E ATOM 16351 CA THR E 238 97958-29185-45840 10011232 E ATOM 16267 OE2 GLU E 227 85190 -25420 -55302 1009844 E ATOM 16352 CB THR E 238 97129-28120-46566 10010698 E

ATOM 16268 C GLU E 227 86507-28999-52482 1005453 E ATOM 16353 OGl THRE238 97969-27016-46913 10010698

ATOM 16269 0 GLU E 227 87669-29031 -52891 1005453 E E

ATOM 16270 N THRE228 86162-28408-51345 1004889 E ATOM 16354 CG2THRE238 96005-27627-45666 10010698 ATOM 16271 CA THR E 228 87138 27729-50507 1004889 E E ATOM 16272 CB THR E 228 86460 -27071 -49294 1005969 E ATOM 16355 C THRE238 97132-30465 45798 10011232 E ATOM 16273 OGl THR E 228 85477-26132-49747 1004568 E ATOM 16356 O THR E 238 96266-30625^4937 10011232 E ATOM 16274 CG2 THR E 228 87494-26358-48432 1004568 E ATOM 16357 N LYS E 239 97410-31364-46741 1009422 E

ATOM 16275 C THR E 228 88219-28664-49992 1004889 E ATOM 16358 CA LYS E 239 96719-32647-46857 1009422 E

ATOM 162760 THRE228 89388-28292-49914 1004889 E ATOM 16359 CB LYS E 239 97692-33723-47357 1009938 E

ATOM 16277 N LEUE229 87827-29875-49622 1006114 E ATOM 16360 CG LYS E 239 97058-35089 -47575 1009938 E ATOM 16278 CA LEU E 229 88789 -30833 -49111 1006114 E ATOM 16361 CD LYS E 239 98000 36018-48314 1009938 E ATOM 16279 CB LEU E 229 88066 -32063 -48572 1005943 E ATOM 16362 CE LYS E 239 98324-35475-49699 1009938 E ATOM 16280 CG LEU E 229 88954-33142-47971 1003131 E ATOM 16363 NZ LYS E 239 99242-36379-50442 1009938 E ATOM 16281 CD1 LEUE229 90032-32529-47068 1003131 E ATOM 16364 C LYS E 239 96089-33082-45539 1009422 E ATOM 16282 CD2LEUE229 88073-3410647187 1003131 E ATOM 16365 O LYS E 239 96774 -33207 -44524 1009422 E

ATOM 16283 C LEUE229 89777-31222-50205 1006114 E ATOM 16366 N THRE240 94779-33305-45566 1005681 E

ATOM 162840 LEUE229 90974-31332-49943 1006114 E ATOM 16367 CA THR E 240 94048 -33707 -44376 1005681 E ATOM 16285 N GLUE230 89279-31412-51429 1007128 E ATOM 16368 CB THR E 240 93217-32540-43813 10010413 E

ATOM 16286 CA GLU E 230 90136 -31771 -52554 1007128 E ATOM 16369 OGl THR E 240 94061 -31400-43622 10010413 ATOM 16287 CB GLU E 230 89297 -32006 -53804 10014660 E E ATOM 16288 CG GLU E 230 88465 -33266 -53730 10011106 E ATOM 16370 CG2 THR E240 92592 -32930 -42480 10010413 ATOM 16289 CD GLU E 230 87682-33524-55001 10011106 E E ATOM 16290 OE1 GLUE230 88299 33509 56086 10011106 E ATOM 16371 C THR E 240 93094-34861-44644 1005681 E ATOM 16291 OE2GLUE230 86454-33751 -54919 10011106 E ATOM 16372 O THR E 240 92623-35048-45762 1005681 E

ATOM 16292 C GLUE230 91185-30692-52819 1007128 E ATOM 16373 N THRE241 92813-35619-43591 1004974 E

ATOM 16293 O GLUE230 92367-30994-52980 1007128 E ATOM 16374 CA THR E 241 91901 -36758-43639 1004974 E

ATOM 16294 N GLU E 231 90752-29434-52854 1005994 E ATOM 16375 CB THR E 241 91934-37510-42312 10010661 E ATOM 16295 CA GLU E 231 91661 -28308 -53071 1005994 E ATOM 16376 OGl THR E 241 93291 -37765 41951 1006631 E ATOM 16296 CB GLU E 231 90882 -26994 -53096 10012936 E ATOM 16377 CG2 THR E 241 91178-38806-42411 1006631 E

ATOM 16297 CG GLU E 231 89759-26957-54113 10010560 E ATOM 16378 C THR E 241 90459 36282-43838 1004974 E ATOM 16298 CD GLU E 231 90256-26993-55547 10010560 E ATOM 16379 0 THR E 241 89724-3684144633 1004974 E ATOM 16299 OEl GLU E 231 91018-27917-55898 10010560 E ATOM 16380 N SER E 242 90065-35244-43100 1005541 E ATOM 16300 OE2GLUE231 89877-26096-56329 10010560 E ATOM 16381 CA SER E 242 88705-34737-43161 1005541 E

ATOM 16301 C GLU E 231 92695-28256-51955 1005994 E ATOM 16382 CB SER E 242 87853-3544342114 1008201 E

ATOM 16302 O GLUE231 93882-28112-52210 1005994 E ATOM 16383 OG SER E 242 88340-3515840818 1005453 E

ATOM 16303 N ILEE232 92232-28375-50717 1005916 E ATOM 16384 C SER E 242 88568-33243-42955 1005541 E

ATOM 16304 CA ILEE232 93118-28350-49562 1005916 E ATOM 16385 0 SER E 242 89516-3255742593 1005541 E

ATOM 16305 CB ILE E 232 92324 -28562 -48242 1007004 E ATOM 16386 N LEU E 243 87349-3276643173 1004896 E

ATOM 16306 CG2 ILE E 232 93266 -28893 -47088 1004009 E ATOM 16387 CA LEU E 243 87009-3136043037 1004896 E

ATOM 16307 CG1 ILEE232 91515-27308-47912 1004009 E ATOM 16388 CB LEU E 243 86916-3072744428 1006050 E

ATOM 16308 CD1 ILEE232 90705-27431 -46626 1004009 E ATOM 16389 CG LEU E 243 86846-2920844452 1003663 E

ATOM 16309 C ILE E 232 94205 29416 49652 1005916 E ATOM 16390 CDl LEU E 243 88089-28631-43785 1003663 E

ATOM 163100 ILEE232 95328-29188-49205 1005916 E ATOM 16391 CD2 LEU E 243 86742 -2873045896 1003663 E

ATOM 16311 N ASNE233 93881 -30571 -50232 1008953 E ATOM 16392 C LEU E 243 85667 -3126842306 1004896 E ATOM 16312 CA ASN E 233 94853-31648-50336 1008953 E ATOM 16393 0 LEU E 243 84775-32071-42540 1004896 E ATOM 16313 CB ASNE233 94147-32996-50433 1008455 E ATOM 16394 N SERE244 85531-3030141407 1004563 E ATOM 16314 CG ASN E 233 93490-33398-49135 1007347 E ATOM 16395 CA SER E 244 84288-3014240662 1004563 E ATOM 16315 ODl ASN E233 93977 -33076 -48057 1007347 E ATOM 16396 CB SER E 244 84458-30633-39224 1004149 E ATOM 16316 ND2 ASN E233 92385-34124-49231 1007347 E ATOM 16397 OG SER E 244 84665-32028 39164 1004364 E

ATOM 16317 C ASNE233 95869-31528-51467 1008953 E ATOM 16398 C SER E 244 83774-2870940611 1004563 E

ATOM 16318 O ASNE233 96842-32287-51497 1008953 E ATOM 16399 0 SER E 244 84549-2775440503 1004563 E

ATOM 16319 N LYS E 234 95662-30592-52392 1008406 E ATOM 16400 N LEU E 245 82457 -2856640701 1004255 E ATOM 16320 CA LYSE234 96616-30423-53489 1008406 E ATOM 16401 CA LEU E 245 81826-2726440606 1004255 E

ATOM 16321 CB LYSE234 96060-29478-54546 1007146 E ATOM 16402 CB LEU E 245 80849-2704741755 1005149 E ATOM 16322 CG LYS E 234 94967 -30129 -55353 1007146 E ATOM 16403 CG LEU E 245 80076 -2573241636 1003548 E ATOM 16323 CD LYS E 234 94428-29238-56443 1007146 E ATOM 16404 CDl LEU E 245 81059 -2457441534 1003548 E

ATOM 16324 CE LYS E 234 93371 -29981 -57255 1007146 E ATOM 16405 CD2 LEU E 245 79145-25568-42826 1003548 E

ATOM 16325 NZ LYSE234 92676-29093-58238 1007146 E ATOM 16406 C LEU E 245 81080-27263-39269 1004255 E

ATOM 16326 C LYS E 234 97977-29943-52982 1008406 E ATOM 16407 O LEU E 245 80076-27945-39109 1004255 E

ATOM 16327 O LYSE234 99010-30453-53415 1008406 E ATOM 16408 N ILEE246 81596-26521 -38298 1004613 E

ATOM 16328 N ASN E 235 97987-28961-52082 1008719 E ATOM 16409 CA ILE E 246 80967-26447-36988 1004613 E ATOM 16329 CA ASN E 235 99249 -28509 -51502 1008719 E ATOM 16410 CB ILE E 246 82014-26534-35868 1004568 E ATOM 16330 CB ASNE235 99107-27148-50800 10012463 E ATOM 16411 CG2 ILE E 246 81325-26541-34519 1002872 E

ATOM 16331 CG ASNE235 100382 26738-50064 10012463 E ATOM 16412 CGl ILE E 246 82862 -27789 -36054 1002872 E ATOM 16332 ODl ASN E 235 100988-2756349382 10012463 ATOM 16413 CDl ILE E 246 82052-29061 -36131 1002872 E ATOM 16333 ND2 ASN E 235 100800 -25479 -50190 10012463 E ATOM 16414 C ILEE246 80227-25130-36841 1004613 E

ATOM 16334 C ASNE235 99516-29604-50471 1008719 E ATOM 16415 O ILE E 246 80827-24060-36915 1004613 E

ATOM 16335 O ASN E 235 98824-29692-49456 1008719 E ATOM 16416 N THR E 247 78923-25200 36637 1002855 E

ATOM 16336 N ASPE236 100512-30441-50740 10010054 E ATOM 16417 CA THRE247 78147-23984-36478 1002855 E

ATOM 16337 CA ASPE236 100839-31559-49862 10010054 E ATOM 16418 CB THR E247 77552-23545-37825 1004701 E

ATOM 16338 CB ASPE236 101960-32388-50490 10014073 E ATOM 16419 OGl THR E 247 77005-22230-37696 1004425 E

ATOM 16339 CG ASP E236 101948 -33827 -50022 10014073 E ATOM 16420 CG2 THR E 247 76457-24514-38272 1004425 E ATOM 16340 ODl ASP E 236 102273 -34078 -48843 10014073 E ATOM 16421 C THR E 247 77037-24247-35465 1002855 E ATOM 16341 OD2 ASP E 236 101600-34707-50837 10014073 E ATOM 16422 O THR E 247 76558-25375-35350 1002855 E

ATOM 16342 C ASP E 236 101200-31213-48414 10010054 E ATOM 16423 N GLY E 248 76639-23216-34726 1002635 E

ATOM 16343 O ASP E 236 101361 -32109-47585 10010054 E ATOM 16424 CA GLY E 248 75602-23380-33722 1002635 E

ATOM 16344 N SER E 237 101319-29927-48102 1009972 E ATOM 16425 C GLY E 248 75552-22200-32789 1002635 E

ATOM 16345 CA SER E 237 101651 -29521 -46737 1009972 E ATOM 16426 O GLY E 248 76222-21202-33026 1002635 E

ATOM 16346 CB SERE237 102562-28288-46739 10011289 E ATOM 16427 N CYS E 249 74762-22300-31730 1004387 E

ATOM 16347 OG SERE237 101832-27112-47039 10011289 E ATOM 16428 CA CYS E 249 74645 -21196 -30790 1004387 E

ATOM 16348 C SERE237 100399-29212-45918 1009972 E ATOM 16429 CB CYS E 249 73481 -20276-31188 1002691 E 65251/C766

ATOM 16430 SG CYS E 249 71858 -20961 -30886 1004568 E ATOM 16515 CA GLY E 260 80504 -20937 -37414 1003684 E ATOM 16431 C CYS E 249 74443-21703-29372 1004387 E ATOM 16516 C GLY E 260 81936-20952-37881 1003684 E

ATOM 16432 O CYS E 249 74372-22916-29146 1004387 E ATOM 16517 O GLY E 260 82476-19926 38312 1003684 E

ATOM 16433 N TYRE250 74347-20777-28417 1003752 E ATOM 16518 N TYR E 261 82578-22104-37774 1004524 E

ATOM 16434 CA TYR E 250 74173 -21162 -27025 1003752 E ATOM 16519 CA TYR E 261 83956 -22205 -38204 1004524 E

ATOM 16435 CB TYR E 250 75527-21526-26431 1004277 E ATOM 16520 CB TYR E 261 84883 -22028 -37019 1005432 E

ATOM 16436 CG TYR E 250 76497-20361 -26436 1003312 E ATOM 16521 CG TYR E 261 84693-23056-35939 1003811 E

ATOM 16437 CDl TYR E 250 76576-19483-25343 1003312 E ATOM 16522 CDl TYR E 261 85396 -24259 -35959 1003811 E

ATOM 16438 CEITYRE250 77423-18387-25369 1003312 E ATOM 16523 CEl TYR E 261 85285-25173-34920 10038 Il E

ATOM 16439 CD2 TYR E250 77296 -20103 -27554 1003312 E ATOM 16524 CD2TYRE261 83857-22798-34853 1003811 E ATOM 16440 CE2 TYR E 250 78144-19000-27591 1003312 E ATOM 16525 CE2TYRE261 83733 -23707 -33807 1003811 E

ATOM 16441 CZ TYR E 250 78205-18148-26501 1003312 E ATOM 16526 CZ TYR E 261 84453 -24894 -33844 1003811 E

ATOM 16442 OH TYR E 250 79034-17052-26563 1003312 E ATOM 16527 OH TYR E 261 84331 -25784-32796 1003811 E

ATOM 16443 C TYR E 250 73562-20064-26178 1003752 E ATOM 16528 C TYR E 261 84235 -23525 -38889 1004524 E

ATOM 16444 0 TYRE250 73663-18875-26501 1003752 E ATOM 16529 O TYR E 261 83454 -24470 -38803 1004524 E

ATOM 16445 N GLU E 251 72931 -20496-25091 1005425 E ATOM 16530 N VAL E 262 85362 -23577 -39583 1004824 E

ATOM 16446 CA GLU E 251 72327 -19625 -24102 1005425 E ATOM 16531 CA VAL E 262 85782 -24765 -40305 1004824 E

ATOM 16447 CB GLU E 251 70809 19603-24235 10010991 E ATOM 16532 CB VAL E 262 86069 -24428 -41778 1004218 E

ATOM 16448 CG GLU E 251 70291-18257-24673 1006353 E ATOM 16533 CGl VAL E 262 86753 -25600 -42448 1003367 E

ATOM 16449 CD GLU E 251 68777-18161-24647 1006353 E ATOM 16534 CG2 VAL E 262 84775 -24085 -42497 1003367 E

ATOM 16450 OE1GLUE251 68181-18420-23573 1006353 E ATOM 16535 C VAL E 262 87057 -25314 -39696 1004824 E ATOM 16451 OE2GLUE251 68188-17814-25701 1006353 E ATOM 16536 O VAL E 262 88052 24607 39607 1004824 E

ATOM 16452 C GLU E 251 72743-20270-22781 1005425 E ATOM 16537 N GLU E 263 87031 -26567 -39264 1005506 E

ATOM 16453 O GLU E 251 71988-21035-22176 1005425 E ATOM 16538 CA GLU E 263 88224-27186-38701 1005506 E

ATOM 16454 N THR E 252 73976-19979-22369 1004909 E ATOM 16539 CB GLU E 263 88028-27591 -37237 1009364 E

ATOM 15455 CA THR E 252 74558-20506-21137 1004909 E ATOM 16540 CG GLU E 263 86852 -28480 -36983 1008024 E

ATOM 16456 CB THR E 252 76063 -20777 -21324 1005156 E ATOM 16541 CD GLU E 263 86731-28867-35523 1008024 E

ATOM 16457 OGl THR E 252 76262-21600-22482 1005156 E ATOM 16542 OEl GLU E 263 86956 -28000 -34641 1008024 E

ATOM 16458 CG2 THR E 252 76627 -21479 -20109 1005156 E ATOM 16543 OE2 GLU E 263 86396 -30043 -35259 1008024 E

ATOM 16459 C THRE252 74383-19463-20041 1004909 E ATOM 16544 C GLU E 263 88643 -28393 -39532 1005506 E

ATOM 16460 0 THRE252 75191 -18547-19922 1004909 E ATOM 16545 O GLU E 263 87863 -28973 40290 1005506 E

ATOM 16461 N GLYE253 73338-19604-19232 1005102 E ATOM 16546 N THR E 264 89905 -28750 -39378 1006339 E ATOM 16462 CA GLY E 253 73096-18610-18200 1005102 E ATOM 16547 CA THR E 264 90522 -29839 -40103 1006339 E

ATOM 16463 C GLYE253 72840-17254-18851 1005102 E ATOM 16548 CB THR E 264 91726-29272-40885 1007805 E

ATOM 16464 0 GLYE253 72012-17138-19765 1005102 E ATOM 16549 OGl THR E 264 91339 -29082 -42243 1005698 E

ATOM 16465 N LEUE254 73550-16226-18397 1005280 E ATOM 16550 CG2 THR E 264 92928 -30160 -40814 1005698 E

ATOM 16466 CA LEU E 254 73397 14890-18971 1005280 E ATOM 16551 C THR E 264 90959 -30903 -39115 1006339 E

ATOM 16467 CB LEU E 254 73972-13816-18054 1004156 E ATOM 16552 O THR E 264 90973 -30673 -37904 1006339 E

ATOM 16468 CG LEUE254 73277-13525-16734 1004156 E ATOM 16553 N ALA E 265 91300-32078-39617 1006061 E

ATOM 16469 CDl LEU E 254 73935 12314-16101 1004156 E ATOM 16554 CA ALA E 265 91756-33141 -38731 1006061 E

ATOM 16470 CD2 LEU E 254 71806-13273-16971 1004156 E ATOM 16555 CB ALA E 265 92054 -34405 -39536 1005308 E

ATOM 16471 C LEU E 254 74101 -14768-20311 1005280 E ATOM 16556 C ALA E 265 93017 -32658 -38007 1006061 E

ATOM 16472 O LEU E 254 73699 -13964 -21148 1005280 E ATOM 16557 O ALA E 265 93354-33151 -36944 1006061 E

ATOM 16473 N LEU E 255 75161 -15548 -20504 1004506 E ATOM 16558 N ASN E 266 93696 31680-38599 1007133 E

ATOM 16474 CA LEU E 255 75910-15495-21749 1004506 E ATOM 16559 CA ASN E 266 94913-31111-38035 1007133 E

ATOM 16475 CB LEUE255 77231-16231 -21595 1003443 E ATOM 16560 CB ASN E 266 95800 -30551 -39144 10013707 E

ATOM 16476 CG LEU E 255 78092-15817-20402 1003443 E ATOM 16561 CG ASN E 266 96103 -31571 -40210 1007892 E

ATOM 16477 CDl LEU E 255 79421 -16571-20440 1003443 E ATOM 16562 ODl ASN E 266 96548 -32677 -39914 1007892 E

ATOM 16478 CD2 LEU E 255 78329 -14323 -20440 1003443 E ATOM 16563 ND2 ASN E 266 95866 -31206 -41464 1007892 E

ATOM 16479 C LEU E 255 75142-16093-22920 1004506 E ATOM 16564 C ASN E 266 94621 -30001 -37036 1007133 E

ATOM 16480 O LEU E 255 74320-16985-22743 1004506 E ATOM 16565 O ASN E 266 95515-29585-36309 1007133 E

ATOM 16481 N PHE E 256 75404-15593-24120 1004282 E ATOM 16566 N GLY E 267 93379-29517-37011 1007227 E

ATOM 16482 CA PHEE256 74747-16101 -25319 1004282 E ATOM 16567 CA GLY E 267 93013-28465-36078 1007227 E

ATOM 16483 CB PHEE256 73303-15598-25391 1005219 E ATOM 16568 C GLY E 267 92212 -27327 -36687 1007227 E

ATOM 16484 CG PHEE256 73178-14116-25569 1004920 E ATOM 16569 O GLY E 267 92030 -27282 -37899 1007227 E

ATOM 16485 CDl PHE E 256 73002 -13567 -26833 1004920 E ATOM 16570 N PRO E 268 91733 -26377 -35864 1006172 E

ATOM 16486 CD2 PHE E 256 73229 -13263 -24470 1004920 E ATOM 16571 CD PRO E 268 92114-26176-34455 1005361 E

ATOM 16487 CEl PHE E 256 72875 -12197 -27000 1004920 E ATOM 16572 CA PRO E 268 90948-25241 -36352 1006172 E

ATOM 16488 CE2PHEE256 73104 11886-24627 1004920 E ATOM 16573 CB PRO E 268 90864 -24327 -35129 1006950 E

ATOM 16489 CZ PHE E 256 72927-11352-25887 1004920 E ATOM 16574 CG PRO E 268 92091 -24683 -34347 1005361 E

ATOM 16490 C PHE E 256 75536-15671-26552 1004282 E ATOM 16575 C PRO E 268 91594 -24571 -37550 1006172 E

ATOM 16491 O PHEE256 76099-14576-26579 1004282 E ATOM 16576 O PRO E 268 92804 -24370 -37588 1006172 E

ATOM 16492 N GLYE257 75598-16546-27554 1004552 E ATOM 16577 N LEU E 269 90767 -24231 -38530 1006013 E

ATOM 16493 CA GLY E 257 76326 -16232 -28769 1004552 E ATOM 16578 CA LEU E 269 91233 -23598 -39747 1006013 E

ATOM 16494 C GLY E 257 76147-17309-29812 1004552 E ATOM 16579 CB LEU E 269 90731 -24402 -40937 1008506 E

ATOM 16495 O GLY E 257 75444-18297-29578 1004552 E ATOM 16580 CG LEU E 269 91411 -24147-42268 1005040 E ATOM 16496 N SER E 258 76776-17129-30968 1003267 E ATOM 16581 CDl LEU E 269 92905-24316-42093 1005040 E

ATOM 16497 CA SER E 258 76669-18103-32042 1003267 E ATOM 16582 CD2 LEU E 269 90866-25111-43310 1005040 E

ATOM 16498 CB SER E 258 75658-17631 -33085 1003455 E ATOM 16583 C LEU E 269 90781-22139-39857 1006013 E

ATOM 16499 OG SERE258 76156-16509-33784 1004467 E ATOM 16584 O LEU E 269 91592-21228-39682 1006013 E

ATOM 16500 C SERE258 78042-18255-32673 1003267 E ATOM 16585 N ALA E 270 89496-21915-40128 1004951 E

ATOM 16501 O SER E 258 78906-17411 -32478 1003267 E ATOM 16586 CA ALA E 270 88968 -20555 -40262 1004951 E

ATOM 16502 N TYR E 259 78252 -19331 -33420 1003170 E ATOM 16587 CB ALA E 270 88875-20169 ^tI 741 1003624 E

ATOM 16503 CA TYR E 259 79544-19551-34051 1003170 E ATOM 16588 C ALA E 270 87613-20353-39599 1004951 E

ATOM 16504 CB TYRE259 80458-20328 33108 1004420 E ATOM 16589 O ALA E 270 86764-21243-39589 1004951 E

ATOM 16505 CG TYR E 259 79816-21598-32604 1003995 E ATOM 16590 N ARG E 271 87413-19147-39082 1005573 E

ATOM 16506 CDl TYR E 259 79807-22764-33382 1003995 E ATOM 16591 CA ARG E 271 86188-18755-38394 1005573 E ATOM 16507 CEl TYR E 259 79116-23893-32967 1003995 E ATOM 16592 CB ARG E 271 86590-18165-370461005115 E

ATOM 16508 CD2 TYR E 259 79122-21612-31393 1003995 E ATOM 16593 CG ARG E 271 85519-17441 -36300 1004427 E

ATOM 16509 CE2 TYR E 259 78431 -22733 -30980 1003995 E ATOM 16594 CD ARG E 271 86096-16839-35034 1004427 E

ATOM 16510 CZ TYRE259 78427-23864-31768 1003995 E ATOM 16595 NE ARG E 271 86476 -17855 -34058 1004427 E

ATOM 16511 OH TYR E 259 77694-24950-31365 1003995 E ATOM 16596 CZ ARG E 271 87727 18196 33765 1004427 E

ATOM 16512 C TYRE259 79417-20296-35361 1003170 E ATOM 16597 NHl ARG E 271 88744 -17606 -34377 1004427

ATOM 16513 O TYR E 259 78382-20890-35659 1003170 E E

ATOM 16514 N GLYE260 80489-20262-36138 1003684 E 65251/C766

ATOM 16598 NH2 ARG E 271 87963 -19116 -32839 1004427 E ATOM 16683 CG LYS E 281 93906 -15368 -39710 I 008004 E ATOM 16599 C ARG E 271 85426-17737-39244 1005573 E ATOM 16684 CD LYS E 281 95058-15013-38778 1008004 E

ATOM 16600 O ARG E 271 86026-16828-39810 1005573 E ATOM 16685 CE LYS E 281 96412-15434-39335 1008004 E

ATOM 16601 N TYRE272 84109-17896-39344 1004931 E ATOM 16686 NZ LYS E 281 97540 -15003 -38450 1008004 E

ATOM 16602 CA TYR E 272 83303 -16979 -40142 1004931 E ATOM 16687 C LYSE281 92012-17552-38145 1005148 E

ATOM 16603 CB TYRE272 82119-17706-40774 1004270 E ATOM 16688 O LYS E 281 91717-16619 37397 1005148 E

ATOM 16604 CG TYR E 272 81274 -16800 -41657 1004017 E ATOM 16689 N MET E 282 92101 -18807-37720 1005463 E

ATOM 16605 CD1 TYRE272 81653-16523-42972 1004017 E ATOM 16690 CA MET E 282 91916-19154-36316 1005463 E

ATOM 16606 CEl TYR E 272 8089S -15666 -43771 1004017 E ATOM 16691 CB MET E 282 91009 -20374 -36160 1006217 E

ATOM 16607 CD2TYRE272 80119-16200^11170 1004017 E ATOM 16692 CG MET E 282 89549 -20139 -36470 1006217 E ATOM 16608 CE2 TYR E 272 79361 -15353-41967 1004017 E ATOM 16693 SD MET E 282 88553 -21482 -35764 1006217 E

ATOM 16609 CZ TYR E 272 79754 -15089 -43259 1004017 E ATOM 16694 CE MET E 282 88509 22561 -37133 1006217 E

ATOM 16610 OH TYR E 272 78997-14252-44033 1004017 E ATOM 16695 C MET E 282 93276-19487-35711 1005463 E

ATOM 16611 C TYRE272 82768-15821 -39317 1004931 E ATOM 16696 O MET E 282 93408-19682-34505 1005463 E

ATOM 16612 0 TYRE272 82065-16037-38334 1004931 E ATOM 16697 N THR E 283 94282 -19560 -36570 1009774 E

ATOM 16613 N HIS E 273 83086-14593-39723 1005228 E ATOM 16698 CA THR E 283 95639-19877-36159 1009774 E

ATOM 16614 CA HISE273 82614-13421-38996 1005228 E ATOM 16699 CB THR E 283 95981 -21328 -36516 1008674 E

ATOM 16615 CB H1SE273 83740 12400 38820 10014284 E ATOM 16700 OGl THR E 283 95145 -22206 -35761 1008674 E

ATOM 16616 CG HIS E 273 84744-12797-37785 10012357 E ATOM 16701 CG2 THR E 283 97424-21636-36204 1008674 E

ATOM 16617 CD2 HIS E 273 86074 -13034 -37874 10012357 E ATOM 16702 C THR E 283 96596-18957-36898 1009774 E

ATOM 16618 NDl HIS E 273 84400 -13036 -36471 10012357 E ATOM 16703 O THR E 283 96242-18400-37938 1009774 E ATOM 16619 CEl HIS E 273 85474-13404-35796 10012357 E ATOM 16704 N HIS E 284 97801-18791-36357 1009045 E

ATOM 16620 NE2 HIS E273 86504-13411 -36624 10012357 E ATOM 16705 CA HIS E 284 98819-17949-36980 1009045 E

ATOM 16621 C HIS E 273 81412-12766-39642 1005228 E ATOM 16706 CB HIS E 284 100103-17985-36150 10014216 E

ATOM 16622 O HIS E 273 81454-12311-40785 1005228 E ATOM 16707 CG HIS E 284 100635-19368 35930 10014216 E

ATOM 16623 N THRE274 80327-12751 -38883 1004145 E ATOM 16708 CD2 HIS E 284 101777 19963-36348 10014216

ATOM 16624 CA THR E 274 79080 -12150 -39304 1004145 E E

ATOM 16625 CB THR E 274 78065-12241 -38159 1006644 E ATOM 16709 NDl HIS E 284 99940-20329-35226 10014216 E

ATOM 16626 OGl THR E 274 77243-13396-38363 1005897 E ATOM 16710 CEl HIS E 284 100630 -21456 -35222 10014216 E

ATOM 16627 CG2THRE274 77218-10973-38065 1005897 E ATOM 16711 NE2 HIS E 284 101749 -21261 -35896 10014216 E

ATOM 16628 C THRE274 79257-10695-39740 1004145 E ATOM 16712 C HIS E 284 99097-18495-38383 1009045 E

ATOM 16629 0 THRE274 78627-10256-40698 1004145 E ATOM 16713 O HIS E 284 99339-17740-39329 1009045 E ATOM 16630 N GLYE275 80112 -9959-39033 1006546 E ATOM 16714 N LYS E 285 99036 -19820 -38494 1007492 E

ATOM 16631 CA GLY E 275 80357 -8570-39368 1006546 E ATOM 16715 CA LYS E 285 99281-20546-39735 1007492 E

ATOM 16632 C GLYE275 81026 -8380-40718 1006546 E ATOM 16716 CB LYS E 285 98951 -22025 -39533 1009736 E

ATOM 16633 O GLYE275 80437 -7800-41633 1006546 E ATOM 16717 CG LYS E 285 100048-22975-39963 1009736 E

ATOM 16634 N ASP E 276 82250 -8882 ^O 849 1006137 E ATOM 16718 CD LYS E 285 101288-22818-39091 1009736 E

ATOM 16635 CA ASP E 276 83023 -8750-42081 1006137 E ATOM 16719 CE LYS E 285 102390 -23791 -39507 1009736 E

ATOM 16636 CB ASP E 276 84469 -9160-41827 10013864 E ATOM 16720 NZ LYS E 285 103608-23666-38655 1009736 E

ATOM 16637 CG ASPE276 85049 8498-40600 10011764 E ATOM 16721 C LYS E 285 98508 -20031 -40947 I 007492 E

ATOM 16638 ODl ASP E 276 85266 -7264-40631 10011764 E ATOM 16722 O LYS E 285 98987 -20129 -42078 1007492 E

ATOM 16639 OD2 ASP E 276 85277 -9216 -39599 10011764 E ATOM 16723 N GLY E 286 97314 -19494 -40715 1008066 E

ATOM 16640 C ASP E 276 82482 -9557-43249 1006137 E ATOM 16724 CA GLY E 286 96506-18991-41814 1008066 E

ATOM 16641 O ASP E 276 82849 -9305-44392 1006137 E ATOM 16725 C GLY E 286 95690 -20119 -42409 1008066 E

ATOM 16642 N LYS E 277 81614-10524-42966 1006072 E ATOM 16726 O GLY E 286 95733-21239-41901 1008066 E

ATOM 16643 CA LYSE277 81039-11371 -44008 1006072 E ATOM 16727 N PHE E 287 94941 -19836 -43470 1007067 E

ATOM 16644 CB LYSE277 80175-10533-44951 1008533 E ATOM 16728 CA PHE E 287 94131 -20866 -44114 1007067 E

ATOM 16645 CG LYS E 277 78921 -9982-44297 1007054 E ATOM 16729 CB PHE E 287 92704-20855-43553 1004331 E

ATOM 16646 CD LYS E 277 78273 -8915-45159 1007054 E ATOM 16730 CG PHE E 287 91902-19652-43942 1004331 E

ATOM 16647 CE LYS E 277 76981 -8393-44547 1007054 E ATOM 16731 CDl PHE E 287 91223 -19612 -45146 1004331 E

ATOM 16648 NZ LYS E 277 75847 -9362 -44685 I 007054 E ATOM 16732 CD2 PHE E 287 91831-18558-43101 1004331 E

ATOM 16649 C LYSE277 82143-12092-44790 1006072 E ATOM 16733 CEl PHE E 287 90483-18493-45507 1004331 E

ATOM 16650 O LYS E 277 82161 -12095 -46025 1006072 E ATOM 16734 CE2 PHE E 287 910S9-17428 -43453 1004331 E

ATOM 16651 N ARGE278 83060-12704-44050 1005198 E ATOM 16735 CZ PHE E 287 90416-17394-44654 1004331 E

ATOM 16652 CA ARG E 278 84178-13435 -44628 1005198 E ATOM 16736 C PHE E 287 94095 -20681 ^t5626 1007067 E

ATOM 16653 CB ARG E 278 85212-12451-45159 1009759 E ATOM 16737 O PHE E 287 94023-19558-46121 1007067 E

ATOM 16654 CG ARG E 278 85945 -11732 -44064 1008222 E ATOM 16738 N PRO E 288 94138-21788-46380 1006614 E

ATOM 16655 CD ARG E 278 86782 -10598 -44600 1008222 E ATOM 16739 CD PRO E 288 94130 -23175 -45893 1005594 E

ATOM 16656 NE ARG E 278 87572 -9970 -43542 1008222 E ATOM 16740 CA PRO E 288 94114-21747-47846 1006614 E

ATOM 16657 CZ ARG E 278 88148 -8775 -43638 1008222 E ATOM 16741 CB PRO E 288 94343 -23202 -48231 1005594 E ATOM 16658 NHl ARG E 278 88028 -8060 -44752 1008222 E ATOM 16742 CG PRO E 288 93674 -23941 -47113 1005594 E ATOM 16659 NH2 ARG E 278 88839 8291-42613 1008222 E ATOM 16743 C PRO E 288 92807 -21195 -48403 1006614 E

ATOM 16660 C ARGE278 84815-14311 ^13538 1005198 E ATOM 16744 O PRO E 288 91724-21701-48103 1006614 E

ATOM 16661 O ARGE278 84500-14165-42354 1005198 E ATOM 16745 N LYS E 289 92905-20148^9211 1006789 E

ATOM 16662 N PHE E 279 85700 -15225 ^t3936 1004783 E ATOM 16746 CA LYS E 289 91714-19550-49793 1006789 E

ATOM 16663 CA PHE E 279 86379-16092-42974 1004783 E ATOM 16747 CB LYS E 289 91982 18089 50156 10010737 E ATOM 16664 CB PHE E 279 86748-17437^)3591 1005704 E ATOM 16748 CG LYS E 289 91965-17172-48937 10010737 E

ATOM 16665 CG PHEE279 85609-18405-43662 1004081 E ATOM 16749 CD LYS E 289 92253-15728-49296 10010737 E

ATOM 16666 CDl PHE E 279 84817-18486-44805 1004081 E ATOM 16750 CE LYS E 289 93713 15537^(9701 10010737 E

ATOM 16667 CD2 PHE E 279 85321-19243-42581 1004081 E ATOM 16751 NZ LYS E 289 94039-14116-50035 10010737 E

ATOM 16668 CEl PHE E 279 83750-19398^4876 1004081 E ATOM 16752 C LYS E 289 91246-20350-51001 1006789 E

ATOM 16669 CE2PHEE279 84264-20147-42640 1004081 E ATOM 16753 O LYS E 289 91488-19984-52152 1006789 E

ATOM 16670 CZ PHE E 279 83477-20229-43788 1004081 E ATOM 16754 N VAL E 290 90562 -21452 -50706 1006779 E

ATOM 16671 C PHE E 279 87648-15447-42473 1004783 E ATOM 16755 CA VAL E 290 90039 -22353 -51723 1006779 E

ATOM 16672 O PHE E 279 88261 -14658 -43170 1004783 E ATOM 16756 CB VAL E 290 90929 -23604 -51854 1005905 E

ATOM 16673 N THR E 280 88047-15803-41264 1004987 E ATOM 16757 CGl VAL E 290 92376 -23189 -52049 1005905 E

ATOM 16674 CA THR E 280 89253 -15254 -40668 1004987 E ATOM 16758 CG2 VAL E 290 90806 -24471 -50605 1005905 E ATOM 16675 CB THRE280 88928-14233 39583 10010922 E ATOM 16759 C VAL E 290 88642-22801-51325 1006779 E

ATOM 16676 OGl THR E 280 88013 -13267 -40104 1008974 E ATOM 16760 O VAL E 290 88212-22592-50188 1006779 E

ATOM 16677 CG2 THR E 280 90193 -13530 -39127 1008974 E ATOM 16761 N GLY E 291 87943 -23422 -52269 1006107 E

ATOM 16678 C THR E 280 90048-16359^0019 1004987 E ATOM 16762 CA GLY E 291 86601 -23912 -52008 1006107 E

ATOM 16679 O THR E 280 89480-17218-39357 1004987 E ATOM 16763 C GLY E 291 85645 -22936 -51343 1006107 E

ATOM 16680 N LYSE281 91363-16325-40210 1005148 E ATOM 16764 O GLY E 291 85512-21785-51757 1006107 E

ATOM 16681 CA LYSE281 92267-17320-39637 1005148 E ATOM 16765 N MET E 292 84973-23410-50301 1006342 E

ATOM 16682 CB LYSE281 93716-16872-39847 10010410 E ATOM 16766 CA MET E 292 84004 -22608 -49568 1006342 E 65251/C766

ATOM 16767 CB MET E 292 83217-23498-48624 1006015 E ATOM 16852 CB ASP E 302 75063 -20790 -51574 1009836 E

ATOM 16768 CG MET E 292 84091 -24013 -47500 1006015 E ATOM 16853 CG ASP E 302 74164 -20698 -52793 1009836 E

ATOM 16769 SD MET E 292 83153-24619-46116 1006015 E ATOM 16854 ODl ASP E 302 73025 -20208 52643 1009836 E

ATOM 16770 CE MET E 292 83578-26328-46151 1006015 E ATOM 16855 OD2 ASP E 302 74586-21118-53894 1009836 E

ATOM 16771 C MET E 292 84672 -21526 -48734 1006342 E ATOM 16856 C ASP E 302 75775 -19674 49440 1004827 E

ATOM 16772 O MET E 292 83998 -20768 -48043 1006342 E ATOM 16857 O ASP E 302 75074 1986048451 1004827 E

ATOM 16773 N LEU E 293 85992-21456-48784 1006320 E ATOM 16858 N VAL E 303 77100-19634-49376 1003268 E

ATOM 16774 CA LEU E 293 86704 -20476 -47987 1006320 E ATOM 16859 CA VAL E 303 77782-19804-48103 1003268 E

ATOM 16775 CB LEU E 293 87972-21107-47414 1005199 E ATOM 16860 CB VAL E 303 79310-19734-48270 1003185 E

ATOM 16776 CG LEU E 293 87732-22260-46431 1005199 E ATOM 16861 CGl VAL E 303 79998 -19777 -46907 1002116 E

ATOM 16777 CDl LEU E 293 89050-22913-46043 1005199 E ATOM 16862 CG2 VAL E 303 79778 -2089749099 1002116 E

ATOM 16778 CD2 LEU E 293 87016-21725 -45206 1005199 E ATOM 16863 C VAL E 303 77334-18690-47160 1003268 E

ATOM 16779 C LEU E 293 87064-19150-48653 1006320 E ATOM 16864 O VAL E 303 76896-1894946033 1003268 E

ATOM 16780 O LEU E 293 87624 -18281 -47988 1006320 E ATOM 16865 N LYS E 304 77444-17449-47628 1005177 E

ATOM 16781 N THR E 294 86766-1897849942 1006094 E ATOM 16866 CA LYS E 304 77027-16279-46843 1005177 E

ATOM 16782 CA THR E 294 87088-17717-50609 1006094 E ATOM 16867 CB LYS E 304 77058-15012-47700 1008951 E

ATOM 16783 CB THR E 294 88144-17868-51696 1008736 E ATOM 16868 CG LYS E 304 78402-14333-47831 1007143 E

ATOM 16784 OGl THR E 294 89156-18770-51253 1008736 E ATOM 16869 CD LYS E 304 78264-13121-48735 1007143 E

ATOM 16785 CG2THRE294 88781 -16509-51990 1008736 E ATOM 16870 CE LYS E 304 79558-12335-48818 1007143 E

ATOM 16786 C THR E 294 85898 -17098 -51284 1006094 E ATOM 16871 NZ LYS E 304 79473 -11230 -49824 1007143 E

ATOM 16787 O THR E 294 84993-17798-51722 1006094 E ATOM 16872 C LYS E 304 75605-16457-46323 1005177 E

ATOM 16788 N VAL E 295 85915-15775-51383 1006147 E ATOM 16873 O LYS E 304 75316 16204-45159 1005177 E

ATOM 16789 CA VAL E 295 84833-15056-52027 1006147 E ATOM 16874 N ALA E 305 74719-1690147202 1004385 E

ATOM 16790 CB VAL E 295 84979-13555-51809 I 008828 E ATOM 16875 CA ALA E 305 73328 -1708946844 1004385 E

ATOM 16791 CGl VAL E 295 83796-12819-52433 1008828 E ATOM 16876 CB ALA E 305 72502-1728248103 1002645 E

ATOM 16792 CG2VALE295 85085-13271 -50318 1008828 E ATOM 16877 C ALA E 305 73075 -1823345877 1004385 E

ATOM 16793 C VAL E 295 84905 -15365 -53512 1006147 E ATOM 16878 O ALA E 305 72411-1804344856 1004385 E

ATOM 16794 O VAL E 295 83916-15218-54236 1006147 E ATOM 16879 N TYR E 306 73593-1941946193 1004584 E

ATOM 16795 N LYS E 296 86082 -15816 -53947 1006362 E ATOM 16880 CA TYR E 306 73369 -20577 -45344 1004584 E

ATOM 16796 CA LYS E 296 86330-16159-55348 1006362 E ATOM 16881 CB TYR E 306 73734 -2185346087 1005348 E

ATOM 16797 CB LYS E 296 87774-16645-55528 10011417 E ATOM 16882 CG TYR E 306 72820 -2214947248 1004817 E

ATOM 16798 CG LYS E 296 88843-15636-55143 10011417 E ATOM 16883 CDl TYR E 306 73287 -2284748367 1004817 E

ATOM 16799 CD LYS E 296 88969-14525-56170 10011417 E ATOM 16884 CEl TYR E 306 72451 -23131 -49442 1004817 E

ATOM 16800 CE LYS E 296 89538-15049-57484 10011417 E ATOM 16885 CD2 TYR E 306 71487-2174547232 1004817 E

ATOM 16801 NZ LYS E 296 89662-13984-58522 10011417 E ATOM 16886 CE2 TYR E 306 70644-2202748299 1004817 E

ATOM 16802 C LYS E 296 85382 17253-55824 1006362 E ATOM 16887 CZ TYR E 306 71 128-2271849398 1004817 E

ATOM 16803 O LYS E 296 85007 17284-56996 1006362 E ATOM 16888 OH TYR E 306 70286-23003-50448 1004817 E

ATOM 16804 N ASN E 297 84995 -18140 -54907 1005003 E ATOM 16889 C TYR E 306 74121 -2052144036 1004584 E

ATOM 16805 CA ASN E 297 84120-19266-55233 1005003 E ATOM 16890 O TYR E 306 73532 -20694 -42980 1004584 E

ATOM 16806 CB ASN E 297 83951-20186-54023 1005176 E ATOM 16891 N LEU E 307 75419-20274-44102 1003675 E

ATOM 16807 CG ASN E 297 83283-21492-54381 1005176 E ATOM 16892 CA LEU E 307 76232 -2023542900 1003675 E

ATOM 16808 ODl ASN E 297 82141 -21521 -54846 1005176 E ATOM 16893 CB LEU E 307 77687-20513-43247 1006634 E

ATOM 16809 ND2 ASN E 297 83994-22585-54171 1005176 E ATOM 16894 CG LEU E 307 78683-2031542106 1003447 E

ATOM 16810 C ASN E 297 82754-18857 -55746 1005003 E ATOM 16895 CDl LEU E 307 78350 2122440942 1003447 E

ATOM 16811 O ASN E 297 82102 -17963 -55208 1005003 E ATOM 16896 CD2 LEU E 307 80090 -2058742629 1003447 E

ATOM 16812 N THR E 298 82327 -19545 -56796 1005254 E ATOM 16897 C LEU E 307 76121 -1890342181 1003675 E

ATOM 16813 CA THR E 298 81046 -19275 -57426 1005254 E ATOM 16898 O LEU E 307 75883 1885740971 1003675 E

ATOM 16814 CB THR E 298 80880 -20166 -58676 1007513 E ATOM 16899 N GLY E 308 76305-17817-42928 1004451 E

ATOM 16815 OGl THR E 298 79498-20238-59036 1007513 E ATOM 16900 CA GLY E 308 76213-16499-42334 1004451 E

ATOM 16816 CG2 THR E 298 81427-21560-58414 1007513 E ATOM 16901 C GLY E 308 74840-1625441733 1004451 E

ATOM 16817 C THR E 298 79857 -19450 -56484 1005254 E ATOM 16902 O GLY E 308 74725-1581040595 1004451 E

ATOM 16818 O THR E 298 78823 -18827 -56675 1005254 E ATOM 16903 N GLY E 309 73791 -1655442489 1004278 E

ATOM 16819 N LEU E 299 80011 -20282-55461 1005513 E ATOM 16904 CA GLY E 309 72448-1632441990 1004278 E

ATOM 16820 CA LEU E 299 78927-20528-54514 1005513 E ATOM 16905 C GLY E 309 72143-1706440708 1004278 E

ATOM 16821 CB LEU E 299 78866 -22010 -54167 1004987 E ATOM 16906 O GLY E 309 71614-16495-39754 1004278 E

ATOM 16822 CG LEU E 299 78472 -22919 -55329 1004987 E ATOM 16907 N PHE E 310 72474 -1834840692 1003486 E

ATOM 16823 CDl LEU E 299 78583 -24360 -54885 1004987 E ATOM 16908 CA PHE E 310 72227-19185-39528 1003486 E

ATOM 16824 CD2 LEU E 299 77059 -22592 -55788 1004987 E ATOM 16909 CB PHE E 310 72730 -20593 -39803 1003718 E

ATOM 16825 C LEU E 299 79014 19712-53226 1005513 E ATOM 16910 CG PHE E 310 72307-21597-38785 1003301 E

ATOM 16826 O LEU E 299 78226 -19907 -52298 1005513 E ATOM 16911 CDl PHE E 310 70960 -21859 -38568 1003301 E

ATOM 16827 N TRP E 300 79969-18795-53171 1004639 E ATOM 16912 CD2PHEE310 73256-22299-38055 1003301 E

ATOM 16828 CA TRP E 300 80136-17951 -52002 1004639 E ATOM 16913 CEl PHE E 310 70561 -22806 -37639 1003301 E

ATOM 16829 CB TRP E 300 81122-16833-52309 1005471 E ATOM 16914 CE2PHEE310 72872-23253-37121 1003301 E

ATOM 16830 CG TRP E 300 81376-15954-51137 1005471 E ATOM 16915 CZ PHE E 310 71518-23506 -36914 1003301 E

ATOM 16831 CD2 TRP E 300 81914-16355 -49876 1005471 E ATOM 16916 C PHE E 310 72940-18620-38311 1003486 E

ATOM 16832 CE2 TRP E 300 81980-15204-49064 1005471 E ATOM 16917 O PHE E 310 72373 -18547 -37224 1003486 E

ATOM 16833 CE3 TRP E 300 82351-17578-49354 1005471 E ATOM 16918 N GLU E 311 74190-18220-38513 1003757 E

ATOM 16834 CDl TRP E 300 81143-14615-51046 1005471 E ATOM 16919 CA GLUE311 75010-17666-37452 1003757 E

ATOM 16835 NEl TRP E 300 81506-14155-49803 1005471 E ATOM 16920 CB GLU E 311 76464-17597-37899 1007677 E

ATOM 16836 CZ2 TRP E 300 82462-15238-47755 1005471 E ATOM 16921 CG GLUE311 77433-17563-36749 1006100 E

ATOM 16837 CZ3 TRP E 300 82831-17611 -48048 1005471 E ATOM 16922 CD GLUE311 78859-17308-37185 1006100 E

ATOM 16838 CH2 TRP E 300 82881-16446 -47266 1005471 E ATOM 16923 OEl GLU E 311 79279 -17837 -38232 1006100 E

ATOM 16839 C TRP E 300 78821-17342-51510 1004639 E ATOM 16924 OE2GLUE311 79573-16586-36467 1006100 E

ATOM 16840 O TRP E 300 78556 -17332 -50309 1004639 E ATOM 16925 C GLU E 311 74544-16271-37055 1003757 E

ATOM 16841 N LYS E 301 78009-16828 52430 1004438 E ATOM 16926 O GLUE311 74630 -15894 -35898 1003757 E

ATOM 16842 CA LYS E 301 76728-16228-52067 1004438 E ATOM 16927 N TYR E 312 74041-15501 -38011 1004425 E

ATOM 16843 CB LYS E 301 75955 -15789 -53322 1008398 E ATOM 16928 CA TYR E 312 73591-14156 -37707 1004425 E

ATOM 16844 CG LYS E 301 76699-14774-54188 1008398 E ATOM 16929 CB TYR E 312 73340 -13365 -38986 1005428 E

ATOM 16845 CD i LYS E 301 77244-13614-53351 1008398 E ATOM 16930 CG TYR E 312 72939-11940-38711 1004898 E

ATOM 16846 CE LYS E 301 78330 -12835 -54095 1008398 E ATOM 16931 CDl TYR E 312 73873-11016-38253 1004898 E

ATOM 16847 NZ LYS E 301 79158-12001 -53175 1008398 E ATOM 16932 CEl TYR E 312 73512 -9701 -37957 1004898 E

ATOM 16848 C LYS E 301 75878 -17202 -51242 1004438 E ATOM 16933 CD2TYRE312 71620-11521 38868 1004898 E

ATOM 16849 O LYS E 301 75186-16793-50319 1004438 E ATOM 16934 CE2TYRE312 71241-10207-38571 1004898 E

ATOM 16850 N ASP E 302 75926 -18492 -51566 1004827 E ATOM 16935 CZ TYRE312 72193 -9300 -38115 1004898 E

ATOM 16851 CA ASP E 302 75149-19465-50813 1004827 E ATOM 16936 OH TYR E 312 71826 -8001 -37804 1004898 E 65251/C766

ATOM 16937 C TYR E 312 72334-14109-36857 1004425 E ATOM 17022 CA LYS E 324 59969-26152-26523 1005323 E

ATOM 16938 O TYR E 312 72192-13230-36015 1004425 E ATOM 17023 CB LYS E 324 59107-25380-27529 1007779 E

ATOM 16939 N MET E 313 71413-15037-37074 1004656 E ATOM 17024 CG LYS E 324 58916-23916-27233 1006722 E

ATOM 16940 CA MET E 313 70176-15013-36314 1004656 E ATOM 17025 CD LYS E 324 57835-23340-28129 1006722 E

ATOM 16941 CB METE313 69281 -13880-36823 1007291 E ATOM 17026 CE LYS E 324 57583-21868-27823 1006722 E

ATOM 16942 CG METE313 67990 -13738 -36059 1007276 E ATOM 17027 NZ LYS E 324 56414-21299 -28566 1006722 E

ATOM 16943 SD MET E 313 66955-12487-36761 1007276 E ATOM 17028 C LYS E 324 59645 -27632 -26665 1005323 E

ATOM 16944 CE MET E 313 68056 11048 36678 I 007276 E ATOM 17029 O LYS E 324 59026 -28236 -25789 1005323 E

ATOM 16945 C MET E 313 69396-16319-36372 1004656 E ATOM 17030 N MET E 325 60056 -28220 -27777 1005232 E

ATOM 16946 O MET E 313 68742-16712-35398 1004656 E ATOM 17031 CA MET E 325 59769-29621-28014 1005232 E

ATOM 16947 N GLY E 314 69462-16987-37518 1003122 E ATOM 17032 CB MET E 325 59992 -29954 -29482 1007223 E

ATOM 1694S CA GLY E 314 68733-18226-37687 1003122 E ATOM 17033 CG MET E 325 59051 -29227-30402 1006079 E

ATOM 16949 C GLY E 314 68817-19168-36522 1003122 E ATOM 17034 SD MET E 325 59347-29645-32118 1006079 E

ATOM 16950 O GLY E 314 67800-19597-35984 1003122 E ATOM 17035 CE MET E 325 60339 -28262 -32633 1006079 E

ATOM 16951 N CYSE315 70040-19490 -36133 1003990 E ATOM 17036 C MET E 325 60578-30572 27151 1005232 E

ATOM 16952 CA CYS E 315 70259-20411-35037 1003990 E ATOM 17037 O MET E 325 60269-31754-27067 1005232 E

ATOM 16953 CB CYS E 315 71746 -20621 -34834 1005775 E ATOM 17038 N ALA E 326 61616 -30075 -26506 1004460 E

ATOM 16954 SG CYS E 315 72098 -22014 -33782 1006312 E ATOM 17039 CA ALA E 326 62423 -30955 -25684 1004460 E

ATOM 16955 C CYSE315 69621 -19958-33727 1003990 E ATOM 17040 CB ALA E 326 63901 -30560 -25798 1003585 E

ATOM 16956 O CYSE315 68870-20712-33101 1003990 E ATOM 17041 C ALA E 326 61979 -30933 -24222 1004460 E

ATOM 16957 N SERE316 69910-18729-33313 1004844 E ATOM 17042 O ALA E 326 62199-31905 -23493 1004460 E

ATOM 16958 CA SER E 316 69345 -18215 -32070 1004844 E ATOM 17043 N LYS E 327 61337 -29837 -23817 1007660 E

ATOM 16959 CB SERE 316 69772-16770-31851 1005671 E ATOM 17044 CA LYS E 327 60899 -29642 -22442 1007660 E

ATOM 16960 OG SER E 316 69162-15928 -32803 1006221 E ATOM 17045 CB LYS E 327 59581-28880-22388 10016018 E

ATOM 16961 C SER E 316 67822 -18305 -32038 1004844 E ATOM 17046 CG LYS E 327 59275 -28392 -20984 1007847 E

ATOM 16962 O SERE316 67236-18404-30967 1004844 E ATOM 17047 CD LYS E 327 58037 -27509 -20934 1007847 E

ATOM 16963 N LEU E 317 67178 18255 33198 1004177 E ATOM 17048 CE LYS E 327 57796 -26957 -19528 1007847 E

ATOM 16964 CA LEU E 317 65726 -18368 -33240 1004177 E ATOM 17049 NZ LYS E 327 56565-26110-19452 1007847 E

ATOM 16965 CB LEU E 317 65174-17748-34527 1005464 E ATOM 17050 C LYS E 327 60777 -30901 -21605 1007660 E

ATOM 16966 CG LEU E 317 65244 -16222 -34625 1004715 E ATOM 17051 O LYS E 327 61550 -31108 -20664 1007660 E

ATOM 16967 CDl LEU E 317 64821 -15755-36005 1004715 E ATOM 17052 N GLY E 328 59826 31761 -21938 1005317 E

ATOM 16968 CD2LEUE317 64347-15617-33556 1004715 E ATOM 17053 CA GLY E 328 59674-32958-21133 1005317 E

ATOM 16969 C LEUE317 65311 -19847-33166 1004177 E ATOM 17054 C GLY E 328 60497 -34190-21482 1005317 E

ATOM 16970 O LEUE317 64368 -20228 -32462 1004177 E ATOM 17055 O GLY E 328 60730-35037 20625 1005317 E

ATOM 16971 N ALAE318 66031 -20684 -33892 1004209 E ATOM 17056 N LYS E 329 60966-34299-22718 1006108 E

ATOM 16972 CA ALA E 318 65732 -22096 -33920 1004209 E ATOM 17057 CA LYS E 329 61694-35495 -23109 1006108 E

ATOM 16973 CB ALA E 318 66619-22779-34917 1003805 E ATOM 17058 CB LYS E 329 61342 -35838 -24559 10018246 E

ATOM 16974 C ALA E 318 65896 -22754 -32566 1004209 E ATOM 17059 CG LYS E 329 59883-36225-24753 10018246 E

ATOM 16975 O ALAE318 65021 -23505 -32119 1004209 E ATOM 17060 CD LYS E 329 59697 -36965 -26062 10018246 E

ATOM 16976 N ILE E 319 67015 -22479 -31902 1004542 E ATOM 17061 CE LYS E 329 58272 -37445 -26257 1007222 E

ATOM 16977 CA ILEE319 67277 -23098 -30614 1004542 E ATOM 17062 NZ LYS E 329 58148 -38201 -27534 1007222 E

ATOM 16978 CB 1LEE319 68498 -22471 -29929 I 004985 E ATOM 17063 C LYS E 329 63209-35614-22911 1006108 E

ATOM 16979 CG2ILEE319 68153-21068-29435 1002441 E ATOM 17064 O LYS E 329 63828 -36501 -23494 1006108 E

ATOM 16980 CGl ILE E 319 68945 -23369 -28768 1002441 E ATOM 17065 N ILE E 330 63823-34757-22101 1004530 E

ATOM 16981 CDl ILE E 319 70232-22936-28069 1002441 E ATOM 17066 CA ILE E 330 65277-34881 -21881 1004530 E

ATOM 16982 C ILE E 319 66074 -23024 29677 1004542 E ATOM 17067 CB ILE E 330 66109 -33878 -22757 1005251 E

ATOM 16983 O ILE E 319 65879 -23926 -28862 1004542 E ATOM 17068 CG2 ILE E 330 65750 -34038 -24236 1005343 E

ATOM 16984 N LEU E 320 65264 -21970 -29803 1005129 E ATOM 17069 CGl ILE E 330 65863 -32445 -22297 1005343 E

ATOM 16985 CA LEU E 320 64092 21818-28952 1005129 E ATOM 17070 CDl ILE E 330 66876 -31471 -22832 1005343 E

ATOM 16986 CB LEU E 320 63554 -20386 -29029 1007594 E ATOM 17071 C ILE E 330 65621 -34657-20410 1004530 E

ATOM 16987 CG LEU E 320 64490 -19303 -28470 1005378 E ATOM 17072 O ILE E 330 64765 -34244 -19633 1004530 E

ATOM 16988 CDl LEU E 320 63817-17947-28583 1005378 E ATOM 17073 N PRO E 331 66878 -34930 -20009 1005408 E

ATOM 16989 CD2 LEU E 320 64843-19597-27011 I 005378 E ATOM 17074 CD PRO E 331 68015 -35375 -20832 1003429 E

ATOM 16990 C LEU E 320 62990 -22827 -29287 1005129 E ATOM 17075 CA PRO E 331 67307-34749-18617 1005408 E

ATOM 16991 O LEU E 320 62238-23255-28401 1005129 E ATOM 17076 CB PRO E 331 68823-34823-18710 10017827 E

ATOM 16992 N ASP E 321 62896 -23223 -30556 1006096 E ATOM 17077 CG PRO E 331 69027-35803 19756 1003429 E

ATOM 16993 CA ASP E 321 61891 -24205 -30957 1006096 E ATOM 17078 C PRO E 331 66846 -33420 - 18055 1005408 E

ATOM 16994 CB ASP E 321 61751-24266-32479 10011687 E ATOM 17079 O PRO E 331 66945-32386-18721 1005408 E

ATOM 16995 CG ASP E 321 61083-23037-33052 1009587 E ATOM 17080 N LYS E 332 66333-33440-16832 1005635 E

ATOM 16996 ODl ASP E 321 60068 -22594 -32471 1009587 E ATOM 17081 CA LYS E 332 65865 -32211 -16194 1005697 E

ATOM 16997 OD2ASPE321 61564 -22524 -34090 1009587 E ATOM 17082 CB LYS E 332 65052-32549-14949 10010438 E

ATOM 16998 C ASP E 321 62289 -25579 -30423 1006096 E ATOM 17083 CG LYS E 332 65863 -33303 -13920 1007592 E

ATOM 16999 O ASP E 321 61432 -26368 -30016 1006096 E ATOM 17084 CD LYS E 332 65249-33212-12552 1007592 E

ATOM 17000 N TYR E 322 63591 -25866 -30423 1004886 E ATOM 17085 CE LYS E 332 66176 -33796 -11508 1007592 E

ATOM 17001 CA TYR E 322 64073 -27150 -29928 1004886 E ATOM 17086 NZ LYS E 332 65632 -33591 -10134 1007592 E

ATOM 17002 CB TYR E 322 65586-27276-30088 1004750 E ATOM 17087 C LYS E 332 67060-31337-15790 1005604 E

ATOM 17003 CG TYR E 322 66062-27564-31495 1003821 E ATOM 17088 O LYS E 332 68182-31827-15624 1005413 E

ATOM 17004 CDl TYR E 322 65987-26593 32491 1003821 E ATOM 17089 N ASP E 333 66817-30043-15631 1006279 E

ATOM 17005 CEl TYR E 322 66479 -26840 -33774 1003821 E ATOM 17090 CA ASP E 333 67880-29134-15229 1006225 E

ATOM 17006 CD2 TYR E 322 66634 -28797 -31824 I 003821 E ATOM 17091 CB ASP E 333 67362-27698-15194 10017617 E

ATOM 17007 CE2 TYR E 322 67127-29050-33101 1003821 E ATOM 17092 CG ASP E 333 67525-26991 -16519 10014376 E

ATOM 17008 CZ TYR E 322 67052-28069-34065 1003821 E ATOM 17093 ODl ASP E 333 67341 -27644-17567 10014376

ATOM 17009 OH TYR E 322 67586-28284-35313 1003821 E E

ATOM 17010 C TYR E 322 63738 -27255 -28455 1004886 E ATOM 17094 OD2 ASP E 333

ATOM 17011 O TYR E 322 63229 -28276 -27987 1004886 E E

ATOM 17012 N GLN E 323 64033 -26184 -27725 1005121 E ATOM 17095 C ASP E 333 68376-29535-13852 1006610 E

ATOM 17013 CA GLN E 323 63776-26143-26297 1005121 E ATOM 17096 O ASP E 333 67596-29937-12994 1006575 E

ATOM 17014 CB GLN E 323 64108 -24769 -25746 1008450 E ATOM 17097 N THR E 334 69680 -29434 -13644 1006213 E

ATOM 17015 CG GLN E 323 63855 -24648 -24272 1005889 E ATOM 17098 CA THR E 334 70269 -29777 -12360 1006185 E

ATOM 17016 CD GLN E 323 64324-23319-23717 1005889 E ATOM 17099 CB THR E 334 70887-31180-12402 1006832 E

ATOM 17017 OEl GLN E 323 63970 -22252 -24234 1005889 E ATOM 17100 OGl THR E 334 69829-32145-12395 1005422 E

ATOM 17018 NE2 GLN E 323 65118-23373-22655 1005889 E ATOM 17101 CG2 THR E 334 71817-31411-11212 1005422 E

ATOM 17019 C GLN E 323 62330 -26485 -25990 1005121 E ATOM 17102 C THR E 334 71322-28760-11969 1006829 E

ATOM 17020 O GLN E 323 62067 27286 25103 1005121 E ATOM 17103 O THR E 334 72303 -28548 -12674 1006565 E

ATOM 17021 N LYS E 324 61395 -25883 -26724 1005323 E ATOM 17104 N THR E 335 71108 -28129 -10829 1005103 E 65251/C766

ATOM 17105 CA THR E 335 72037 -27128 -10354 1005082 E ATOM 17190 OE2 GLU E346 105 210 -30401 -6560 1 0020084

ATOM 17106 CB THR E 335 71393 -26257 -9349 1006264 E E

ATOM 17107 OGl THR E 335 70069 -25908 -9782 1005200 E ATOM 17191 C GLU E 346 105 928 -24 530 -7072 1 00200 84 E

ATOM 17108 CG2 THR E 335 72238 -25000 -9166 1005200 E ATOM 17192 0 GLU E 346 106 331 -23 572 -6404 1 00200 84 E

ATOM 17109 C THR E 335 73293 27703 9732 1005168 E ATOM 17193 N ASP E 347 106 259 -24 697 -8 353 1 00200 84 E

ATOM 17110 O THR E 335 73243-28613 -8913 1005303 E ATOM 17194 CA ASP E 347 107 125 -23 733 -9 037 1 00200 84 E

ATOM 17111 N PRO E 336 74446 -27144 -10090 1005082 E ATOM 17195 CB ASP E 347 107449 -24 206 -10 465 1 00161 62 E

ATOM 17112 CD PRO E 336 74661 -26044 -11044 1002860 E ATOM 17196 CG ASP E 347 106356 -23 864 -11 463 1 00161 62 E

ATOM 17113 CA PRO E 336 75721 -27623 -9566 1005040 E ATOM 17197 ODl ASP E 347 105 218 -24356 -11 304 1 00161 62

ATOM 17114 CB PRO E 336 76698-27152-10621 1003746 E E

ATOM 17115 CG PRO E 336 76155-25786-10922 1002860 E ATOM 17198 OD2 ASP E 347 106 638 -23 100 -12410 1 00161 62

ATOM 17116 C PRO E 336 76110-27103 -8195 1005044 E E

ATOM 17117 O PRO E 336 75462 -26240 -7629 1005107 E ATOM 17199 C ASP E 347 106 517 -22 328 -9 077 1 00200 84 E

ATOM 17118 N THR E 337 77200 -27656 -7688 1005306 E ATOM 17200 O ASP E 347 107 229 -21 330 -8 943 1 00200 84 E

ATOM 17119 CA THR E 337 77780-27281 -6413 1005652 E ATOM 17201 N GLY E 348 105 200 22 256 -9260 1 00200 84 E

ATOM 17120 CB THR E 337 78031-28515 -5544 10010585 E ATOM 17202 CA GLY E 348 104 522 -20 972 -9 303 1 00200 84 E

ATOM 17121 OGl THR E 337 76781 -29002 -5055 1005674 E ATOM 17203 C GLY E 348 103 899 -20 627 -7963 1 00200 84 E

ATOM 17122 CG2 THR E 337 78931 -28179 -4375 1005674 E ATOM 17204 O GLY E 348 103 483 -21 516 -7219 1 0019632 E

ATOM 17123 C THR E 337 79121 -26676 -6815 1 006409 E ATOM 17205 N ASN E 349 103 824 -19 337 -7 647 1 0020039 E

ATOM 17124 O THR E 337 79855-27260 -7617 1005547 E ATOM 17206 CA ASN E 349 103 253 -18907 -6 376 1 00200 29 E

ATOM 17125 N VAL E 338 79447 -25505 6283 1003905 E ATOM 17207 CB ASN E 349 103 136 -17374 -6 337 1 00107 13 E

ATOM 17126 CA VAL E 338 80711 -24884 -6644 1004591 E ATOM 17208 CG ASN E 349 102 784 -16775 -7 686 1 00 92 31 E

ATOM 17127 CB VAL E 338 SO 496 -23527 -7336 1003643 E ATOM 17209 ODl ASN E 349 103 543 -16 886 -8 657 1 00 92 31 E

ATOM 17128 CGl VAL E 338 81809 23020 -7907 I 003605 E ATOM 17210 ND2 ASN E 349 101 631 -16 129 -7752 1 00 92 31 E

ATOM 17129 CG2 VAL E 338 79454 -23665 -8432 1003605 E ATOM 17211 C ASN E 349 101 912 -19 563 -6 027 1 00200 39 E

ATOM 17130 C VAL E 338 81588-24669 -5431 1005038 E ATOM 17212 O ASN E 349 101 888 -20 560 -5 303 1 00200 39 E

ATOM 17131 O VAL E 338 81090-24422 -4331 1 005021 E ATOM 17213 N MET E 350 100 806 -19 026 -6 543 1 00132 02 E

ATOM 17132 N LYS E 339 82897 -24770 -5645 1005379 E ATOM 17214 CA MET E 350 99 484 -19 576 -6236 1 00128 11 E

ATOM 17133 CA LYS E 339 83890-24585 -4597 1005167 E ATOM 17215 CB MET E 350 98 676 -18 538 -5 460 1 00153 51 E

ATOM 17134 CB LYS E 339 84151-25907 -3867 10014015 E ATOM 17216 CG MET E 350 97 280 -18 987 -5 080 1 00108 19 E

ATOM 17135 CG LYS E 339 82950-26421 -3088 10010846 E ATOM 17217 SD MET E 350 96 430 -17 774 -4 053 1 00108 19 E

ATOM 17136 CD LYS E 339 82888 -27947 -3048 10010846 E ATOM 17218 CE MET E 350 96 608 -18 557 -2420 1 00108 19 E

ATOM 17137 CE LYS E 339 81584 -28428 -2411 10010846 E ATOM 17219 C MET E 350 98 663 -20066 -7434 1 00125 25 E

ATOM 17138 NZ LYS E 339 81389-29898 -2532 10010846 E ATOM 17220 O MET E 350 98 860 19 618 -8 560 1 00121 68 E

ATOM 17139 C LYS E 339 85145-24131 -5304 1006066 E ATOM 17221 N THR E 351 97 736 -20987 -7 174 1 00 8405 E

ATOM 17140 O LYS E 339 85527 -24708 -6322 1005332 E ATOM 17222 CA THR E 351 96 877 -21 538 -8 216 1 00 82 01 E

ATOM 17141 N VAL E 340 85773-23082 -4791 1005581 E ATOM 17223 CB THR E 351 97 339 -22 967 -8 645 1 00103 76 E

ATOM 17142 CA VAL E 340 87007 -22577 -5393 1005324 E ATOM 17224 OGl THR E 351 97055 -23 158 -10 032 I 00 70 88 E

ATOM 17143 CB VAL E 340 86976-21048 -5572 1005051 E ATOM 17225 CG2 THR E 351 96 601 -24 052 -7 869 1 0070 88 E

ATOM 17144 CGl VAL E 340 88292-20587 -6166 1003597 E ATOM 17226 C THR E 351 95434 -21 609 -7 719 1 007624 E

ATOM 17145 CG2 VAL E 340 85797 -20636 -6454 1003597 E ATOM 17227 O THR E 351 95 172 -22 023 -6 591 1 00 67 83 E

ATOM 17146 C VAL E 340 88163-22903 -4456 1005581 E ATOM 17228 N LEU E 352 94497 -21 188 -8 557 1 005943 E

ATOM 17147 O VAL E 340 88134 -22507 -3304 1005266 E ATOM 17229 CA LEU E 352 93 089 -21 235 -8 192 1 00 62 45 E

ATOM 17148 N THR E 341 89179-23612 -4937 1008400 E ATOM 17230 CB LEU E 352 92 453 -19 858 -8 367 1 00 81 68 E

ATOM 17149 CA THR E 341 90302 -23966 -4075 1007990 E ATOM 17231 CG LEU E 352 92 789 -18 939 -7 194 1 00 62 74 E

ATOM 17150 CB THR E 341 90566-25479 -4111 10012355 E ATOM 17232 CDl LEU E 352 92 397 -17 518 -7503 1 0062 74 E

ATOM 17151 OGl THR E 341 89395 -26173 -3669 10010491 E ATOM 17233 CD2 LEU E 352 92 063 -19 439 -5 946 1 00 62 74 E

ATOM 17152 CG2 THR E 341 91733 -25840 -3205 10010491 E ATOM 17234 C LEU E 352 92 347 -22 280 -9014 1 0059 13 E

ATOM 17153 C THR E 341 91581 -23238 -4456 008205 E ATOM 17235 O LEU E 352 92 541 -22 391 -10 227 1 00 54 75 E

ATOM 17154 O THR E 341 91847-23000 -5633 008365 E ATOM 17236 N GLU E 353 91 502 -23 050 -8 338 1 00 63 36 E

ATOM 17155 N GLY E 342 92375 -22892 -3447 007312 E ATOM 17237 CA GLU E 353 90 740 -24 097 -8 992 1 00 59 61 E

ATOM 17156 CA GLY E 342 93622-22198 -3693 1007729 E ATOM 17238 CB GLU E 353 91 258 -25 459 -8 559 1 0018756 E

ATOM 17157 C GLY E 342 94842 -23067 -3463 1007626 E ATOM 17239 CG GLU E 353 90 551 -26 612 -9218 1 00146 11 E

ATOM 17158 O GLY E 342 95629 -22805 -2567 1007053 E ATOM 17240 CD GLU E 353 91 039 -27 938 -8 696 1 00146 11 E

ATOM 17159 N ASN E 343 95002-24110 -4271 10012486 E ATOM 17241 OEl GLU E 353 92 259 -28 191 -8 779 1 00146 11 E

ATOM 17160 CA ASN E 343 96153-25001 -4147 I 0013127 E ATOM 17242 OE2 GLU E 353 90207 -28 725 -8 199 1 00146 11 E

ATOM 17161 CB ASN E 343 95989-26218 -5066 10018912 E ATOM 17243 C GLU E 353 89255 -23 997 -8 682 1 0062 86 E

ATOM 17162 CG ASN E 343 94670-26939 -4857 10016892 E ATOM 17244 O GLU E 353 88 831 -24 165 -7 539 1 0063 64 E

ATOM 17163 ODl ASN E 343 94396-27458 -3774 10016892 E ATOM 17245 N CYS E 354 88 473 -23 723 -9 717 1 0076 30 E

ATOM 17164 ND2 ASN E 343 93845 -26974 -5898 10016892 E ATOM 17246 CA CYS E 354 87 030 -23 600 -9 592 1 00 76 58 E

ATOM 17165 C ASN E 343 97387-24215 -4572 10012933 E ATOM 17247 C CYS E 354 86 459 -24 930 -10 041 1 00 7767 E

ATOM 17166 O ASN E 343 97349-22988 -4666 10011796 E ATOM 17248 O CYS E 354 86 715 -25 359 -11 163 1 00 76 37 E

ATOM 17167 N GLU E 344 98479-24923 -4831 10020084 E ATOM 17249 CB CYS E 354 86 528 -22491 -10515 1 00111 67 E

ATOM 17168 CA GLU E 344 99709-24281 -5273 10020084 E ATOM 17250 SG CYS E 354 84837 -21 891 -10210 1 00 88 86 E

ATOM 17169 CB GLU E 344 100385 23556 -4103 10011233 E ATOM 17251 N THR E 355 85 712 -25 605 -9 175 1 00 61 87 E

ATOM 17170 CG GLU E 344 99908 -22113 -3959 1009223 E ATOM 17252 CA THR E 355 85 124 -26 880 -9 575 1 00 51 23 E

ATOM 17171 CD GLU E 344 100441 -21426 -2722 1009223 E ATOM 17253 CB THR E 355 85 667 -28059 -8 755 1 00 9805 E

ATOM 17172 OEl GLU E 344 99956-21737 -1616 1009223 E ATOM 17254 OGl THR E 355 84 726 -28 415 -7741 1 0047 20 E

ATOM 17173 OE2 GLU E 344 101346 -20578 -2853 1009223 E ATOM 17255 CG2 THR E 355 86 981 -27 693 -8 116 1 0047 20 E

ATOM 17174 C GLU E 344 100651 -25283 -5927 10020084 E ATOM 17256 C THR E 355 83 614 -26 829 -9437 1 0064 72 E

ATOM 17175 O GLU E 344 101238-26135 -5264 10020084 E ATOM 17257 O THR E 355 83 077 -26 467 -8 384 1 00 57 52 E

ATOM 17176 N LEU E 345 100780 -25149 -7245 10020084 E ATOM 17258 N VAL E 356 82 942 -27 185 -10 526 1 00 52 96 E

ATOM 17177 CA LEU E 345 101598 -26025 -8069 10020084 E ATOM 17259 CA VAL E 356 81 491 -27 171 -10 580 1 0048 68 E

ATOM 17178 CB LEU E 345 101 181 -25861 -9536 10020084 E ATOM 17260 CB VAL E 356 81 021 -26377 -11 807 1 00 57 79 E

ATOM 17179 CG LEU E 345 99737-26242 -9922 10015450 E ATOM 17261 CGl VAL E 356 79 532 -26 130 -11 733 1 0042 32 E

ATOM 17180 CDl LEU E 345 99570-26113-11431 10015450 E ATOM 17262 CG2 VAL E 356 81 759 -25 061 -11 859 1 004232 E

ATOM 17181 CD2 LEU E 345 99408-27668 -9481 10015450 E ATOM 17263 C VAL E 356 81 024 -28 610 -10 641 00 57 52 E

ATOM 17182 C LEU E 345 103131 -25942 -7934 10020084 E ATOM 17264 O VAL E 356 81 365 -29 341 -11 569 00 58 63 E

ATOM 17183 O LEU E 345 103863 -26143 -8903 10020084 E ATOM 17265 N ASN E 357 80231 -29 007 -9 650 1 0049 80 E

ATOM 17184 N GLU E 346 103605 -25656 -6726 10020084 E ATOM 17266 CA ASN E 357 79 787 -30388 -9 549 1 00 4602 E

ATOM 17185 CA GLU E 346 105035-25594 -6423 10020084 E ATOM 17267 CB ASN E 357 80022 -30910 -8 132 1 00124 63 E

ATOM 17186 CB GLU E 346 105643-26976 -6651 10020084 E ATOM 17268 CG ASN E 357 81 486 -30954 -7 773 1 00 78 55 E

ATOM 17187 CG GLU E 346 104759 -28096 -6121 10020084 E ATOM 17269 ODl ASN E 357 82 292 -31 550 -8 490 1 00 78 55 E

ATOM 17188 CD GLU E 346 105478 -29411 -5846 10020084 E ATOM 17270 ND2 ASN E 357 81 844 -30 318 -6 659 1 0078 55 E

ATOM 17189 OEl GLU E 346 106326 -29448 -4925 10020084 E ATOM 17271 C ASN E 357 78 385 -30 727 -9960 1 00 50 18 E 65251/C766

ATOM 17272 O ASN E 357 77410-30131 -9494 1005306 E ATOM 17357 CB TRP E 368 89174-15860-13674 1008121 E

ATOM 17273 N SER E 358 78324 31739 10823 1005567 E ATOM 17358 CG TRP E 368 89088-17321-13446 1006113 E

ATOM 17274 CA SER E 358 77100 -32287 -11386 1006297 E ATOM 17359 CD2 TRP E 368 89098-17988-12181 1006113 E

ATOM 17275 CB SER E 358 76605 -33460 -10522 1006322 E ATOM 17360 CE2 TRP E 368 88943-19369-12435 1006113 E

ATOM 17276 OG SER E 358 76183-33015 -9260 1006156 E ATOM 17361 CE3 TRP E 368 89221-17554-10855 1006113 E

ATOM 17277 C SER E 358 75969 -31288 -11664 1006769 E ATOM 17362 CDl TRP E 368 88932-18291 -14390 1006113 E

ATOM 17278 O SER E 358 75102-31022-10822 1006324 E ATOM 17363 NEl TRP E 368 88845-19524-13793 1006113 E

ATOM 17279 N PHE E 359 76007 -30756 12884 1004005 E ATOM 17364 CZ2 TRP E 368 88909-20324-11409 1006113 E

ATOM 17280 CA PHE E 359 75023 -29800 -13403 1003436 E ATOM 17365 CZ3 TRP E 368 89185-18506 -9832 1006113 E

ATOM 17281 CB PHE E 359 75735 -28492 -13742 1004759 E ATOM 17366 CH2 TRP E 368 89031 -19874-10117 1006113 E

ATOM 17282 CG PHE E 359 77008 -28677 -14519 1004219 E ATOM 17367 C TRP E 368 87980-13669-13599 1005219 E

ATOM 17283 CDl PHE E 359 76982-28846-15905 1004219 E ATOM 17368 O TRP E 368 88564-13096-14513 1005238 E

ATOM 17284 CD2PHEE359 78242 -28645 -13872 1004219 E ATOM 17369 N ILE E 369 87462-13029-12559 1005535 E

ATOM 17285 CE 1 PHE E 359 78175-28973-16638 1004219 E ATOM 17370 CA ILE E 369 87535-11583-12433 1005672 E

ATOM 17286 CE2 PHE E 359 79436 -28772 -14596 1004219 E ATOM 17371 CB ILE E 369 86127-10985-12538 1006711 E

ATOM 17287 CZ PHE E 359 79401-28934-15980 1004219 E ATOM 17372 CG2 ILE E 369 86194 -9474 -12496 1004479 E

ATOM 17288 C PHE E 359 74424-30427-14668 1004095 E ATOM 17373 CGl ILE E 369 85471 -11461 -13834 1004479 E

ATOM 17289 O PHE E 359 75147-31126 15382 1003850 E ATOM 17374 CDl ILE E 369 84023-11055-13969 1004479 E

ATOM 17290 N TYR E 360 73140 -30219 -14974 1009510 E ATOM 17375 C ILE E 369 88151-11164-11098 1005854 E

ATOM 17291 CA TYR E 360 72685 -30882 -16177 1009488 E ATOM 17376 O ILE E 369 87808 -11720 -10054 1005534 E

ATOM 17292 CB TYR E 360 71196-31208-16244 10015681 E ATOM 17377 N GLU E 370 89060-10190-11131 1005513 E

ATOM 17293 CG TYR E 360 70912-31684-17673 1004395 E ATOM 17378 CA GLU E 370 89691 -9698 -9907 1005778 E

ATOM 17294 CDl TYR E 360 71758-32627-18291 1004395 E ATOM 17379 CB GLU E 370 90725 -8627-10246 10011438 E

ATOM 17295 CEl TYR E 360 71629 -32954 -19639 1004395 E ATOM 17380 CG GLU E 370 92005 -9227-10791 1009302 E

ATOM 17296 CD2TYRE360 69915-31099-18454 1004395 E ATOM 17381 CD GLU E 370 92950 -8199 -11378 1009302 E

ATOM 17297 CE2 TYR E 360 69774 -31427 -19808 1004395 E ATOM 17382 OEl GLU E 370 93207 -7173-10713 1009302 E

ATOM 17298 CZ TYR E 360 70636 -32351 -20395 1004395 E ATOM 17383 OE2GLUE370 93448 -8426 -12504 1009302 E

ATOM 17299 OH TYR E 360 70505 -32661 -21740 1004395 E ATOM 17384 C GLU E 370 88591 9149 -8998 1005796 E

ATOM 17300 C TYR E 360 73019-30270-17506 1009597 E ATOM 17385 O GLU E 370 87731 -8388 -9437 1005681 E

ATOM 17301 O TYR E 360 73967-30706-18138 10010190 E ATOM 17386 N SER E 371 88612 -9554 -7733 1006029 E

ATOM 17302 N PRO E 361 72235 -29285 -17974 1006339 E ATOM 17387 CA SER E 371 87586 -9149 -6773 1006083 E

ATOM 17303 CD PRO E 361 71431-25293-17237 1004377 E ATOM 17388 CB SER E 371 87863 -9795 -5413 1008761 E

ATOM 17304 CA PRO E 361 72664 -28796 -19295 1005898 E ATOM 17389 OG SER E 371 89148 -9439 -4943 1007669 E

ATOM 17305 CB PRO E 361 71883-27489-19465 1004301 E ATOM 17390 C SER E 371 87388 -7650 -6591 1006010 E

ATOM 17306 CG PRO E 361 71663 -27030 -18042 1004377 E ATOM 17391 O SER E 371 86312 -7212 -6167 1006104 E

ATOM 17307 C PRO E 361 74188-28687-19215 1006638 E ATOM 17392 N GLU E 372 88415 -6861 -6902 1006138 E

ATOM 17308 O PRO E 361 74736-27926 18424 1006355 E ATOM 17393 CA GLU E 372 88308 -5414 -6747 1005993 E

ATOM 17309 N PRO E 362 74888-29533-19985 1004431 E ATOM 17394 CB GLU E 372 89581 -4728 -7231 1009763 E

ATOM 17310 CD PRO E 362 74267 -30436 -20972 1003492 E ATOM 17395 CG GLU E 372 89919 -5042 -8662 1009763 E

ATOM 17311 CA PRO E 362 76351-29623 20049 1003802 E ATOM 17396 CD GLU E 372 90964 -4110 -9237 1009763 E

ATOM 17312 CB PRO E 362 76587-30772-21031 1003492 E ATOM 17397 OEl GLU E 372 90688 -2891 -9310 1009763 E

ATOM 17313 CG PRO E 362 75411-30714-21911 1003492 E ATOM 17398 OE2 GLU E 372 92057 -4593 -9617 1009763 E

ATOM 17314 C PRO E 362 77150 28381 20382 1004062 E ATOM 17399 C GLU E 372 87112 -4881 -7528 1006454 E

ATOM 17315 O PRO E 362 78359 -28346 -20154 1004538 E ATOM 17400 O GLU E 372 86383 -4001 -7061 1006561 E

ATOM 17316 N ASP E 363 76491 -27361-20917 1003915 E ATOM 17401 N HIS E 373 86905 -5441 -8714 1005434 E

ATOM 17317 CA ASP E 363 77192-26133-21246 1003900 E ATOM 17402 CA HIS E 373 85818 -5032 -9594 1005783 E

ATOM 17318 CB ASP E 363 76412-25317-22299 1006766 E ATOM 17403 CB HIS E 373 85958 5726 10938 1009553 E

ATOM 17319 CG ASP E 363 74921 -25179 -21978 1006187 E ATOM 17404 CG HIS E 373 87221 -5378-11651 1006488 E

ATOM 17320 ODl ASP E 363 74234-26224-21858 1006187 E ATOM 17405 CD2 HIS E 373 88223 -6154-12134 1006488 E

ATOM 17321 OD2 ASP E 363 74437 -24023 -21860 1006187 E ATOM 17406 NDl HIS E 373 87581 -4076 11919 1006488 E

ATOM 17322 C ASP E 363 77425 -25308 -19978 1004254 E ATOM 17407 CEl HIS E 373 88750 -4063 -12536 1006488 E

ATOM 17323 O ASP E 363 76501 -25000 -19223 1003904 E ATOM 17408 NE2 HIS E 373 89161 -5311-12678 1006488 E

ATOM 17324 N VAL E 364 78680-24980-19727 1004684 E ATOM 17409 C HIS E 373 84419 -5260 -9056 1005360 E

ATOM 17325 CA VAL E 364 79036-24170-18576 1004916 E ATOM 17410 O HIS E 373 83460 -4798 -9654 1004944 E

ATOM 17326 CB VAL E 364 79500-25022-17385 1005848 E ATOM 17411 N PHE E 374 84285 -5971 -7941 1008786 E

ATOM 17327 CGl VAL E 364 80311 -24186-16433 1003687 E ATOM 17412 CA PHE E 374 82959 -6197 -7389 1008863 E

ATOM 17328 CG2 VAL E 364 78311 -25547-16638 1003687 E ATOM 17413 CB PHE E 374 82821 -7636 -6905 1008352 E

ATOM 17329 C VAL E 364 80177 -23280 -18994 1005650 E ATOM 17414 CG PHE E 374 82719 -8616 -8019 1006370 E

ATOM 17330 O VAL E 364 81055-23686 19744 1004824 E ATOM 17415 CDl PHE E 374 83861 -9083 -8657 1006370 E

ATOM 17331 N ILE E 365 80152-22047-18533 1004666 E ATOM 17416 CD2PHEE374 81473 -9026 -8479 1006370 E

ATOM 17332 CA ILE E 365 81227-21138-18848 1004071 E ATOM 17417 CEl PHE E 374 83766 -9945 -9739 1006370 E

ATOM 17333 CB ILE E 365 80814-20087-19883 1006377 E ATOM 17418 CE2PHEE374 81368 -9884 -9559 1006370 E

ATOM 17334 CG2 ILE E 365 81915-19041-20026 1004021 E ATOM 17419 CZ PHE E 374 82518-10345-10191 1006370 E

ATOM 17335 CGl ILE E 365 80558-20778-21228 1004021 E ATOM 17420 C PHE E 374 82637 -5224 -6274 1008471 E

ATOM 17336 CDl ILE E 365 80163-19838-22332 1004021 E ATOM 17421 O PHE E 374 81638 -5375 -5573 1008295 E

ATOM 17337 C ILE E 365 81675-20482-17564 1004747 E ATOM 17422 N LYS E 375 83490 -4214 -6133 1006361 E

ATOM 17338 O ILE E 365 80874 -20198 -16666 1004824 E ATOM 17423 CA LYS E 375 83333 -3187 -5111 1006624 E

ATOM 17339 N THR E 366 82976 -20254 -17489 1003398 E ATOM 17424 CB LYS E 375 82655 -1951 -5710 10012658 E

ATOM 17340 CA THR E 366 83593-19689-16317 1004226 E ATOM 17425 CG LYS E 375 83572 1027 6512 10010042 E

ATOM 17341 CB THR E 366 84495-20756-15706 1006941 E ATOM 17426 CD LYS E 375 84027 -1635 -7830 10010042 E

ATOM 17342 OGl THR E 366 84082 -21001 -14365 1005709 E ATOM 17427 CE LYS E 375 84864 -0640 -8634 10010042 E

ATOM 17343 CG2 THR E 366 85949 -20339 -15744 1005709 E ATOM 17428 NZ LYS E 375 85371 -1215 -991710010042 E

ATOM 17344 C THR E 366 84388-18431-16622 1005124 E ATOM 17429 C LYS E 375 82560 -3630 -3870 1007126 E

ATOM 17345 O THR E 366 85116-18366-17615 1005048 E ATOM 17430 O LYS E 375 81567 -3012 -3507 1007352 E

ATOM 17346 N LYS E 367 84234-17429-15765 1004768 E ATOM 17431 N GLY E 376 83002 -4703 -3227 1007537 E

ATOM 17347 CA LYS E 367 84962-16169-15911 1005088 E ATOM 17432 CA GLY E 376 82318 -5146 -2028 1007537 E

ATOM 17348 CB LYS E 367 84019-15002 16230 1006718 E ATOM 17433 C GLY E 376 81093 -6032 -2179 1007537 E

ATOM 17349 CG LYS E 367 83468-15023 17625 1005819 E ATOM 17434 O GLY E 376 80819 -6839 -12861007537 E

ATOM 17350 CD > LYS E 367 82757-13733-17986 1005819 E ATOM 17435 N GLU E 377 80339 -5882 -3269 1006668 E

ATOM 17351 CE LYS E 367 82432-13720-19475 1005819 E ATOM 17436 CA GLU E 377 79156-6718 -3493 1006668 E

ATOM 17352 NZ LYS E 367 82008 12379 19969 1005819 E ATOM 17437 CB GLU E 377 77987-5876 -3991 10010561 E

ATOM 17353 C LYS E 367 85693-15856-14621 1005358 E ATOM 17438 CG GLU E 377 76667-6631 -3995 10010561 E

ATOM 17354 O LYS E 367 85100-15905-13536 1005389 E ATOM 17439 CD GLU E 377 75500 -5766 -4433 10010561 E

ATOM 17355 N TRP E 368 86982-15545-14747 1005018 E ATOM 17440 OEl GLU E 377 74337 -6218 -4311 10010561 E

ATOM 17356 CA TRP E 368 87809-15180-13604 1005024 E ATOM 17441 OE2 GLU E 377 75748 -4635 -4902 10010561 E 65251/C766

ATOM 17442 C GLU E 377 79463 -7 S19 -4512 1006668 E ATOM 17527 CZ TYR E 386 80232 -7115-12873 1005222 E ATOM 17443 O GLU E 377 79747 7531 -5675 1006668 E ATOM 17528 OH TYR E 386 79157 -6972-12025 1005222 E

ATOM 17444 N TYR E 378 79402 -9078 -4074 1007681 E ATOM 17529 C TYRE386 85383 -6853-16961 1005924 E

ATOM 17445 CA TYR E 378 79709-10197 -4956 1007681 E ATOM 17530 0 TYR E 386 85282 -7636-17897 1005924 E

ATOM 17446 CB TYR E 378 80405 11309 4171 1008486 E ATOM 17531 N PRO E 387 86573 -6386-16553 1005716 E

ATOM 17447 CG TYR E 378 81786-10906 -3735 1008486 E ATOM 17532 CD PRO E 387 86866 -5271-15639 1006707 E

ATOM 17448 CDl TYR E 378 82009-10351 -2476 1008486 E ATOM 17533 CA PRO E 387 87799 -6857-17220 1005716 E

ATOM 17449 CEl TYR E 378 83274 -9902 -2101 1008486 E ATOM 17534 CB PRO E 387 88891 -6059-16520 1006707 E

ATOM 17450 CD2 TYR E 378 82861 -11007 -4609 100 S486 E ATOM 17535 CG PRO E 387 88189 -4784-16161 1006707 E

ATOM 17451 CE2TYRE378 84124-10561 -4251 1008486 E ATOM 17536 C PROE387 87817 -8344-16825 1005716 E ATOM 17452 CZ TYR E 378 84326 -10009 -2996 1008486 E ATOM 17537 0 PROE387 87383 -8665-15717 1005716 E

ATOM 17453 OH TYR E 378 85582 -9562 -2643 1008486 E ATOM 17538 N GLU E 388 88306 -9259-17660 1009202 E

ATOM 17454 C TYRE378 78540-10757 -5760 1007681 E ATOM 17539 CA GLU E 388 88188-10639-17214 1009202 E

ATOM 17455 O TYR E 378 78103-11896 -5571 1007681 E ATOM 17540 CB GLU E 388 86918-11236-17816 10010185 E

ATOM 17456 N LYS E 379 78044 -9921 -6663 1005105 E ATOM 17541 CG GLU E 388 86985-11453-19308 10010185 E

ATOM 17457 CA LYS E 379 76954-10263 -7573 1005105 E ATOM 17542 CD GLU E 388 85838 -12302 -19810 10010185 E

ATOM 17458 CB LYS E 379 75660 -9556 -7184 1008900 E ATOM 17543 OEl GLU E 388 85684-13440-19323 10010185

ATOM 17459 CG LYS E 379 75069-10017 5869 1008900 E E

ATOM 17460 CD LYS E 379 73795 -9242 -5559 1008900 E ATOM 17544 OE2 GLU E 388 85089-11833-20689 10010185

ATOM 17461 CE LYS E 379 73260 -9541 -4160 1008900 E E

ATOM 17462 NZ LYS E 379 72117 8643 -3818 1008900 E ATOM 17545 C GLU E 388 89269-11713-17279 1009202 E ATOM 17463 C LYS E 379 77407 -9775 -8941 1005105 E ATOM 17546 0 GLUE388 88932-12894-17217 1009202 E

ATOM 17464 O LYS E 379 77998 -8703 9059 1005105 E ATOM 17547 N TRPE389 90545-11372-17380 10010291 E

ATOM 17465 N TYRE380 77166-10578 -9970 1004371 E ATOM 17548 CA TRP E 389 91546-12445-17397 10010291 E

ATOM 17466 CA TYR E 380 77558-10220-11332 1004371 E ATOM 17549 CB TRP E 389 91606-13130-16025 10011538 E

ATOM 17467 CB TYR E 380 77842-11481-12138 1004660 E ATOM 17550 CG TRP E 389 92679-12662-15103 10011538 E

ATOM 17468 CG TYR E 380 78359-11210-13520 1004660 E ATOM 17551 CD2 TRP E 389 93759-11763-15403 10011538 E

ATOM 17469 CDl TYR E 380 79724 -11027 -13754 1004660 E ATOM 17552 CE2TRPE389 94537 11642 14232 10011538 E

ATOM 17470 CEl TYR E 380 80208-10782-15036 1004660 E ATOM 17553 CE3 TRP E 389 94146-11048-16549 10011538 E

ATOM 17471 CD2 TYR E 380 77485-11138-14604 1004660 E ATOM 17554 CDl TRP E 389 92844-13036-13803 10011538 E

ATOM 17472 CE2 TYR E 380 77957-10890-15887 1004660 E ATOM 17555 NEl TRP E 389 93955-12429-13272 10011538 E

ATOM 17473 CZ TYR E 380 79318-10714-16097 1004660 E ATOM 17556 CZ2 TRP E 389 95682-10835-14171 10011538 E ATOM 17474 OH TYR E 380 79784-10479-17371 1004660 E ATOM 17557 CZ3 TRP E 389 95286-10246-16487 10011538 E

ATOM 17475 C TYR E 380 76384 -9469-11940 1004371 E ATOM 17558 CH2 TRP E 389 96039-10148-15305 10011538 E

ATOM 17476 0 TYRE380 75333-10058-12189 1004371 E ATOM 17559 C TRPE389 91222-13518-18437 10010291 E

ATOM 17477 N VALE381 76555 -8172-12159 1005204 E ATOM 17560 0 TRPE389 90831 -14628-18079 10010291 E

ATOM 17478 CA VAL E 381 75483 -7349-12710 1005204 E ATOM 17561 N GLYE390 91391 -13198-19714 1008611 E

ATOM 17479 CB VAL E 381 75684 -5869-12352 1006167 E ATOM 17562 CA GLY E 390 91098-14167-20756 1008611 E

ATOM 17480 CGl VAL E 381 74509 -5052-12843 1006167 E ATOM 17563 C GLYE390 91983-15402-20737 1008611 E

ATOM 17481 CG2VALE381 75840 -5728 10857 1006167 E ATOM 17564 0 GLYE390 93107-15368-20237 1008611 E

ATOM 17482 C VALE381 75421 -7494-14222 1005204 E ATOM 17565 N ARGE391 91460-16501 -21274 1009853 E

ATOM 17483 O VALE381 76392 -7188-14922 1005204 E ATOM 17566 CA ARG E 391 92199-17758-21349 1009853 E

ATOM 17484 N ASNE382 74268 7932 14718 1008306 E ATOM 17567 CB ARG E 391 91229-18943-21246 1009707 E

ATOM 17485 CA ASN E 382 74084 -8168-16141 1008306 E ATOM 17568 CG ARG E 391 90398-18979-19954 1009707 E

ATOM 17486 CB ASN E 382 72611 -8192-16496 1004S50 E ATOM 17569 CD ARG E 391 91008-19880-18863 1009707 E

ATOM 17487 CG ASN E 382 72337 -9031-17739 1004850 E ATOM 17570 NE ARG E 391 90525-21265-18913 1009707 E

ATOM 17488 ODl ASN E 382 73171 -9118-18650 1004850 E ATOM 17571 CZ ARG E 391 90940-22189-19783 1009707 E

ATOM 17489 ND2 ASN E 382 71161 -9648-17784 1004850 E ATOM 17572 NHl ARG E 391 91863 -21892 -20692 1009707

ATOM 17490 C ASNE382 74788 -7221 -17101 1008306 E E

ATOM 17491 O ASN E 382 75858 -7544-17638 1008306 E ATOM 17573 NH2ARGE391 90423 23412 19753 1009707

ATOM 17492 N GLYE383 74200 -6056-17339 1004358 E E

ATOM 17493 CA GLY E 383 74835 -5142-18278 1004358 E ATOM 17574 C ARGE391 92906-17760-22707 1009853 E

ATOM 17494 C GLYE383 76160 -4485-17898 1004358 E ATOM 17575 0 ARGE391 92601 16933-23563 1009853 E

ATOM 17495 O GLY E 383 76702 -3713-18686 1004358 E ATOM 17576 N LYSE392 93855-18668-22905 1007610 E

ATOM 17496 N ARGE384 76698 -4779-16719 1005080 E ATOM 17577 CA LYS E 392 94566-18732-24179 1007610 E

ATOM 17497 CA ARG E 384 77939 ^1143-16292 1005080 E ATOM 17578 CB LYS E 392 96079-18714-23944 10010764 E

ATOM 17498 CB ARG E 384 78090 ^) 287 -14780 1005451 E ATOM 17579 CG LYS E 392 96888-18762-25232 10010764 E

ATOM 17499 CG ARG E 384 79240 -3501-14179 1005451 E ATOM 17580 CD LYS E 392 98366-18980-24966 10010764 E

ATOM 17500 CD ARG E 384 79059 -3408-12677 1005451 E ATOM 17581 CE LYS E 392 99126-19193-26272 10010764 E

ATOM 17501 NE ARG E 384 77788 -2770-12348 1005451 E ATOM 17582 NZ LYS E 392 100546-19583-26035 10010764 E

ATOM 17502 CZ ARG E 384 77270 -2702-11126 1005451 E ATOM 17583 C LYS E 392 94184-19986-24980 1007610 E

ATOM 17503 NHl ARG E 384 77916 -3237 10096 1005451 E ATOM 175840 LYSE392 94456-21113-24558 1007610 E

ATOM 17504 NH2 ARG E 384 76101 -2102-10930 1005451 E ATOM 17585 N SER E 393 93554-19778-26137 1007008 E

ATOM 17505 C ARGE384 79185 -4664-16987 1005080 E ATOM 17586 CA SER E 393 93125 -20877 -26999 1007008 E

ATOM 17506 O ARG E 384 79253 -5828-17370 1005080 E ATOM 17587 CB SER E 393 91880-21553-26416 1007314 E

ATOM 17507 N TYRE385 80169 -3788-17150 1005511 E ATOM 17588 OG SER E 393 91403-22575 27278 1007314 E ATOM 17508 CA TYRE 385 81422 -4163-17783 1005511 E ATOM 17589 C SERE393 92801-20353-28386 1007008 E

ATOM 17509 CB TYR E 385 82067 -2944-18428 1006790 E ATOM 17590 0 SERE393 92531-19167-28550 1007008 E

ATOM 17510 CG TYR E 385 83456 -3230-18915 1006790 E ATOM 17591 N ASN E 394 92834-21230 29385 1005881 E

ATOM 17511 CDl TYR E 385 83666 -3979-20066 1006790 E ATOM 17592 CA ASN E 394 92509-20814-30743 1005881 E

ATOM 17512 CEl TYR E 385 84949 -4318-20474 1006790 E ATOM 17593 CB ASN E 394 93012-21826-31759 1007126 E

ATOM 17513 CD2 TYR E 385 84566 -2820-18181 1006790 E ATOM 17594 CG ASN E 394 94510-21813-31888 1007126 E

ATOM 17514 CE2 TYR E 385 85856 -3154-18577 1006790 E ATOM 17595 ODl ASN E 394 95125-20753-32051 1007126 E

ATOM 17515 CZ TYR E 385 86042 -3905-19726 1006790 E ATOM 17596 ND2 ASN E 394 95113-22996-31829 1007126 E

ATOM 17516 OH TYR E 385 87320 -4245-20123 1006790 E ATOM 17597 C ASN E 394 91005-20667-30876 1005881 E

ATOM 17517 C TYRE385 82389 -4745-16746 1005511 E ATOM 17598 O ASN E 394 90502-20025-31797 1005881 E

ATOM 17518 O TYRE385 82434 -4274-15609 1005511 E ATOM 17599 N TYR E 395 90298-21274-29937 1004676 E ATOM 17519 N TYR E 386 83161 -5761-17139 1005924 E ATOM 17600 CA TYR E 395 88855-21218-29907 1004676 E

ATOM 17520 CA TYR E 386 84138 -6378-16242 1005924 E ATOM 17601 CB TYR E 395 88291 -22564-29461 1005072 E

ATOM 17521 CB TYR E 386 83574 -7620-15548 1005222 E ATOM 17602 CG TYR E 395 88562-23695-30412 1005072 E

ATOM 17522 CG TYR E 386 82403 7413 14618 1005222 E ATOM 17603 CDl TYR E 395 89647-24539-30224 1005072 E

ATOM 17523 CDl TYR E 386 81099 -7622 -15054 1005222 E ATOM 17604 CEl TYR E 395 89915-25579-31108 1005072 E

ATOM 17524 CEl TYR E 386 80016 -7479-14190 1005222 E ATOM 17605 CD2 TYR E 395 87737-23916-31518 1005072 E

ATOM 17525 CD2 TYR E 386 82601 -7045-13287 1005222 E ATOM 17606 CE2 TYR E 395 87994-24951 -32411 1005072 E

ATOM 17526 CE2 TYR E 386 81522 -6894-12411 1005222 E ATOM 17607 CZ TYR E 395 89089 25780 32199 1005072 E 65251/C766

ATOM 17S0S OH TYR E 395 89361 -26804 -33086 1005072 E ATOM 17693 CB ILE E 406 83054-30828-19134 1006801 E

ATOM 17609 C TYR E 395 88413-20148-28921 1004676 E ATOM 17694 CG2 ILE E 406 81701-31318-18621 1005563 E

ATOM 17610 O TYR E 395 89149-19820-27992 1004676 E ATOM 17695 CGl ILE E 406 83122-29311-19041 1005563 E

ATOM 17611 N GLU E 396 87213-19606-29124 1005200 E ATOM 17696 CDl ILE E 406 82006 -28601 -19777 1005563 E

ATOM 17612 CA GLU E 396 86654 -18598 -28228 1005200 E ATOM 17697 C ILE E 406 84186 -32941 -18530 1005333 E

ATOM 17613 CB GLU E 396 85956-17498-29025 10010594 E ATOM 17698 O ILE E 406 84762-33414-19508 1004843 E

ATOM 17614 CG GLU E 396 86772-16933-30162 10010594 E ATOM 17699 N LYS E 407 83551 -33679 -17622 1005282 E

ATOM 17615 CD GLU E 396 85947 -16048 -31072 10010594 E ATOM 17700 CA LYS E 407 83437-35128-17749 1004842 E

ATOM 17616 OEl GLU E 396 84881 -16510-31540 10010594 E ATOM 17701 CB LYS E 407 84443-35855-16863 10010003 E

ATOM 17617 OE2 GLU E 396 86360-14898-31327 10010594 E ATOM 17702 CG LYS E 407 85886-35601-17222 1008613 E

ATOM 17618 C GLU E 396 85624-19333-27371 1005200 E ATOM 17703 CD LYS E 407 86799-36512-16421 1008613 E

ATOM 17619 O GLU E 396 84912 -20206 -27870 1005200 E ATOM 17704 CE LYS E 407 88274-36169-16632 1008613 E

ATOM 17620 N PRO E 397 85546-19016-26068 1004574 E ATOM 17705 NZ LYS E 407 88630-34835-16066 1008613 E

ATOM 17621 CD PRO E 397 86251 -17986-25296 1004129 E ATOM 17706 C LYS E 407 82041 -35458-17285 1005773 E

ATOM 17622 CA PRO E 397 84557 19708 25235 1004574 E ATOM 17707 O LYS E 407 81553-34836 16344 1005667 E

ATOM 17623 CB PRO E 397 84652-18980-23888 1004129 E ATOM 17708 N LYS E 408 81378-36397-17959 1006197 E

ATOM 17624 CG PRO E 397 85225-17640-24251 1004129 E ATOM 17709 CA LYS E 408 80038-36779-17541 1006156 E

ATOM 17625 C PRO E 397 83183 -19604 -25885 1004574 E ATOM 17710 CB LYS E 408 79341-37589-18625 1006109 E

ATOM 17626 O PRO E 397 82788-18534-26359 1004574 E ATOM 17711 CG LYS E 408 77900-37899-18295 1005989 E

ATOM 17627 N GLY E 398 82475 -20730 -25924 1004455 E ATOM 17712 CD LYS E 408 77185-38443-19505 1005989 E

ATOM 17628 CA GLY E 398 81172-20772-26559 1004455 E ATOM 17713 CE LYS E 408 75713-38663-19226 1005989 E

ATOM 17629 C GLY E 398 81244 -21747 -27719 1004455 E ATOM 17714 NZ LYS E 408 74979 -39085 -20453 1005989 E

ATOM 17630 O GLY E 398 80313-22513-27944 1004455 E ATOM 17715 C LYS E 408 80273-37629-16310 1006169 E

ATOM 17631 N GLU E 399 82350-21715-28460 1004108 E ATOM 17716 O LYS E 408 80787-38731-16405 1006026 E

ATOM 17632 CA GLU E 399 82556 -22628 -29593 1004108 E ATOM 17717 N ASP E 409 79929-37119-15142 1006728 E

ATOM 17633 CB GLU E 399 83781 -22202 -30430 1004790 E ATOM 17718 CA ASP E 409 80183-37893-13946 1006746 E

ATOM 17634 CG GLU E 399 83745 -20762 -30905 1004790 E ATOM 17719 CB ASP E 409 79944 -37050 -12675 1008894 E

ATOM 17635 CD GLU E 399 84936 -20365 -31772 1004790 E ATOM 17720 CG ASP E 409 78643 -36270 -12706 1008176 E

ATOM 17636 OEl GLU E 399 86076 -20732 -31437 1004790 E ATOM 17721 ODl ASP E 409 77602-36860-13059 1008176 E

ATOM 17637 OE2 GLU E 399 84740 -19659 -32786 1004790 E ATOM Mill OD2 ASP E 409 78665 -35070 -12358 1008176 E

ATOM 17638 C GLU E 399 82810-24012-28989 1004108 E ATOM 17723 C ASP E 409 79417-39212-13891 1006737 E

ATOM 17639 O GLU E 399 83540 -24142 -28011 1004108 E ATOM 17724 O ASP E 409 78466-39420-14648 1007110 E

ATOM 17640 N PRO E 400 82205 25065 -29545 1006172 E ATOM 17725 N LYS E 410 79883^10094-13001 10012491 E

ATOM 17641 CD PRO E 400 81244 -25177 30650 1004424 E ATOM 17726 CA LYS E 410 79338-41433-12757 10013135 E

ATOM 17642 CA PRO E 400 82467 -26375 -28943 1005680 E ATOM 17727 CB LYS E 410 79487-41796-11276 10018014 E

ATOM 17643 CB PRO E 400 81652-27340-29821 1009285 E ATOM 17728 CG LYS E 410 78612-40977-10322 10011959 E

ATOM 17644 CG PRO E 400 81443 -26609 -31089 I 004424 E ATOM 17729 CD LYS E 410 79091 -39532 -10174 10011959 E

ATOM 17645 C PRO E 400 83946 -26756 -28837 1004755 E ATOM 17730 CE LYS E 410 78166-38728 9260 10011959 E

ATOM 17646 O PRO E 400 84319 27602-28033 1004776 E ATOM 17731 NZ LYS E 410 78610-37310 -9092 10011959 E

ATOM 17647 N GLY E 401 84794-26105-29621 1005080 E ATOM 17732 C LYS E 410 77887-41629-13161 10013017 E

ATOM 17648 CA GLY E 401 86209 26421-29575 1005036 E ATOM 17733 O LYS E 410 77111 ^tO 580 -13198 10012970 E

ATOM 17649 C GLY E 401 86959 -25889 -28365 1005015 E ATOM 17734 N ASPE411 77527 -42879-13432 1007835 E

ATOM 17650 O GLY E 401 88125 -26225 -28169 1005086 E ATOM 17735 CA ASP E 411 76171 -43240-13852 1007586 E

ATOM 17651 N PHE E 402 86315-25056-27551 1005801 E ATOM 17736 CB ASP E 411 75774-44598-13269 10014528 E

ATOM 17652 CA PHE E 402 86983 -24509 -26376 1005801 E ATOM 17737 CG ASP E 411 76184-45754-14159 10014528 E

ATOM 17653 CB PHE E 402 86157-23389-25754 10015651 E ATOM 17738 ODl ASP E 411 75856 -45725 -15366 I 0014528

ATOM 17654 CG PHE E 402 86965 -22482 -24894 1005484 E E

ATOM 17655 CDl PHE E 402 87811-21534-25473 1005484 E ATOM 1177773399 OODD22AASSPPEE441111 76828-46695-13655 10014528

ATOM 17656 CD2 PHE E 402 86947-22617-23516 1005484 E E

ATOM 17657 CEl PHE E 402 88632 -20738 -24694 1005484 E ATOM 17740 C ASP E 411 75085 -42219-13527 1007747 E

ATOM 17658 CE2 PHE E 402 87761 -21829 -22722 1005484 E ATOM 17741 O ASP E 411 74385^2336-12521 1008165 E

ATOM 17659 CZ PHE E 402 88611 -20883 -23314 1005484 E ATOM 17742 N ALA E 412 74944-41229-14406 1008241 E

ATOM 17660 C PHE E 402 87230 -25602 -25332 1005801 E ATOM 17743 CA ALA E 412 73958-40172-14240 1009543 E

ATOM 17661 O PHE E 402 86312 -26330 -24956 1005801 E ATOM 17744 CB ALAE412 74323-39309-13041 1005180 E

ATOM 17662 N PRO E 403 88477 -25722 -24842 1007816 E ATOM 17745 C ALA E 412 73906-39323-15505 1009013 E

ATOM 17663 CD PRO E 403 89612 24874 25224 1005143 E ATOM 17746 O ALA E 412 74717-39500-16416 1008518 E

ATOM 17664 CA PRO E 403 88910-26708 -23847 1007816 E ATOM 17747 N ASN E 413 72950 -38401 -15554 I 007238 E

ATOM 17665 CB PRO E 403 90427-26544-23819 10015626 E ATOM 17748 CA ASN E 413 72792-37528-16711 1006519 E

ATOM 17666 CG PRO E 403 90742 -25823 -25070 1005143 E ATOM 17749 CB ASN E 413 71321-37177-16901 1006439 E

ATOM 17667 C PRO E 403 88334 -26495 -22462 1007816 E ATOM 17750 CG ASN E 413 70470 -38388 17168 1006439 E

ATOM 17668 O PRO E 403 88799 -25640 -21721 1007816 E ATOM 17751 ODl ASN E 413 70850-39264-17953 1006439 E

ATOM 17669 N TRP E 404 87315-27258-22112 1005596 E ATOM 17752 ND2ASNE413 69302 -38443 -16532 1006439 E

ATOM 17670 CA TRP E 404 86735 -27155 -20786 1005596 E ATOM 17753 C ASN E 413 73571 36243-16552 1006977 E

ATOM 17671 CB TRP E 404 85235 -26830 -20838 1006711 E ATOM 17754 O ASN E 413 73768-35500-17501 1006946 E

ATOM 17672 CG TRP E 404 84893-25404-21171 1006035 E ATOM 17755 N THR E 414 74024-36003-15337 1004586 E

ATOM 17673 CD2 TRP E 404 85237 -24232 -20420 1006035 E ATOM 17756 CA THR E 414 74731-34789-14999 1004890 E

ATOM 17674 CE2 TRP E 404 84679 -23126 -21094 1006035 E ATOM 17757 CB THR E 414 74543 -34524 -13506 1008643 E

ATOM 17675 CE3 TRP E 404 85962-24007-19240 1006035 E ATOM 17758 OGl THR E 414 75238-33339-13150 1005692 E

ATOM 17676 CDl TRP E 404 84164 -24970 -22238 1006035 E ATOM 17759 CG2THRE414 75056-35681-12689 1005692 E

ATOM 17677 NEl TRP E 404 84030-23608-22201 1006035 E ATOM 17760 C THR E 414 76213-34768-15387 1004836 E

ATOM 17678 CZ2 TRP E 404 84824 -21807 -20629 1006035 E ATOM 17761 O THR E 414 76774-35797-15731 1004943 E

ATOM 17679 CZ3 TRP E 404 86105-22689-18778 1006035 E ATOM 17762 N TYRE415 76826-33582-15354 1004807 E

ATOM 17680 CH2 TRP E 404 85538 -21613 -19474 1006035 E ATOM 17763 CA TYR E 415 78237-33397-15719 1004910 E

ATOM 17681 C TRP E 404 86928-28536-20191 1005596 E ATOM 17764 CB TYRE415 78376 -32625 -17040 1006606 E

ATOM 17682 O TRP E 404 86622 29534 -20836 1005596 E ATOM 17765 CG TYRE415 77859-33341 -18261 1003300 E

ATOM 17683 N ASN E 405 87439 -28605 -18969 1005292 E ATOM 17766 CDl TYR E 415 76494 -33553 -18447 1003300 E

ATOM 17684 CA ASN E 405 87646 -29895 -18334 1005295 E ATOM 17767 CEl TYRE415 76018-34229-19561 1003300 E

ATOM 17685 CB ASN E 405 88666-29765-17213 1008979 E ATOM 17768 CD2TYRE415 78740 -33826 -19229 1003300 E

ATOM 17686 CG ASN E 405 89314-31071 -16885 1008979 E ATOM 17769 CE2TYRE415 78268 34510-20355 1003300 E

ATOM 17687 ODl ASN E 405 88699 -31956 -16294 1008979 E ATOM 17770 CZ TYR E 415 76909 -34706 -20509 1003300 E

ATOM 17688 ND2 ASN E 405 90565 -31214 -17287 1008979 E ATOM 17771 OH TYRE415 76445 -35390 -21605 1003300 E

ATOM 17689 C ASN E 405 86329-30434-17788 1006189 E ATOM 17772 C TYRE415 78983-32607-14657 1005666 E

ATOM 17690 O ASN E 405 86082-30410-16578 1005495 E ATOM 17773 O TYR E 415 78370-31927-13838 1005131 E

ATOM 17691 N ILE E 406 85482 -30911 -18692 1005426 E ATOM 17774 N SERE416 80312-32678-14703 1003880 E

ATOM 17692 CA ILE E 406 84194-31448-18304 1004646 E ATOM 17775 CA SER E 416 81162-31971 -13747 1003675 E 65251/C766

ATOM 17776 CB SER E 416 81704-32924-12695 1006539 E ATOM 17861 CG MET E 427 96741 -11329 -9768 10014386 E

ATOM 17777 OG SER E 416 80681-33274-11791 1004177 E ATOM 17862 SD MET E 427 95545-12634 -9485 10014386 E

ATOM 17778 C SER E 416 82313 -31296 -14458 1004294 E ATOM 17863 CE MET E 427 95674-13557-11031 10014386 E

ATOM 17779 O SER E 416 82787-31774-15495 1004131 E ATOM 17864 C MET E 427 97346 -8258 -9735 10015739 E

ATOM 17780 N LEU E 417 82761 30184 13884 1004744 E ATOM 17865 O MET E 427 98452 -7808 -9437 10015739 E

ATOM 17781 CA LEU E 417 83832 -29383 -14463 1004634 E ATOM 17866 N SER E 428 96251 -8029 -9016 10012774 E

ATOM 17782 CB LEU E 417 83222-28146-15125 1009823 E ATOM 17867 CA SER E 428 96288 -7206 -7815 10012939 E

ATOM 17783 CG LEU E 417 84130-26920-15223 1005634 E ATOM 17868 CB SER E 428 96570 -5750 -8194 10010306 E

ATOM 17784 CDl LEU E 417 85099-27100-16371 1005634 E ATOM 17869 OG SER E 428 95531 5226 -9006 1009977 E

ATOM 17785 CD 2 LEU E 417 83300 -25681 -15426 1005634 E ATOM 17870 C SER E 428 94992 -7271 -7007 10012534 E

ATOM 17786 C LEU E 417 84886-28928-13455 1005785 E ATOM 17871 O SER E 428 94622 -6300 -6349 10012522 E

ATOM 17787 O LEU E 417 84602 -28725 -12269 1005295 E ATOM 17872 N SER E 429 94303 -8408 -7050 10013496 E

ATOM 17788 N THR E 418 86102-28747-13951 1004248 E ATOM 17873 CA SER E 429 93055 -8558 -6305 10013363 E

ATOM 17789 CA THR E 418 87211-28290-13130 1003554 E ATOM 17874 CB SER E 429 91911 -7844 -7030 1009218 E

ATOM 17790 CB THR E 418 88145 -29452 -12765 1007400 E ATOM 17875 OG SER E 429 92132 -6451 -7108 1009218 E

ATOM 17791 OGl THR E 418 87493-30311 -11824 1004241 E ATOM 17876 C SER E 429 92658-10013 -6090 10013201 E

ATOM 17792 CG2THRE418 89437-28928-12164 1004241 E ATOM 17877 O SER E 429 91729 -10305 -5338 10012071 E

ATOM 17793 C THR E 418 88006-27261 -13917 1005073 E ATOM 17878 N GLN E 430 93366 -10925 -6742 1007817 E

ATOM 17794 O THR E 418 88588 -27590 -14942 1004420 E ATOM 17879 CA GLN E 430 93043 -12345 -6636 1007817 E

ATOM 17795 N ASP E 419 88031 -26017-13458 1004732 E ATOM 17880 CB GLN E 430 93019-12812 -5185 10015627 E

ATOM 17796 CA ASP E 419 88778-24987 14173 1005243 E ATOM 17881 CG GLN E 430 92755 -14291 -5080 1008526 E

ATOM 17797 CB ASP E 419 87848 -23857 -14605 1009500 E ATOM 17882 CD GLN E 430 92682 -14769 -3659 1008526 E

ATOM 17798 CG ASP E 419 88490-22950-15619 1007259 E ATOM 17883 OEl GLN E 430 91743 -14446 -2932 I 008526 E

ATOM 17799 ODl ASPE419 89072 23469-16591 1007259 E ATOM 17884 NE2GLNE430 93681-15544 -3244 1008526 E

ATOM 17800 OD2ASPE419 88417-21721 -15458 1007259 E ATOM 17885 C GLN E 430 91669-12560 -7265 1007817 E

ATOM 17801 C ASP E 419 89898 -24448 -13298 1005652 E ATOM 17886 O GLN E 430 90645-12127 -6736 1007817 E

ATOM 17802 O ASP E 419 89658 23988-12178 1005141 E ATOM 17887 N PRO E 431 91632-13260 -8401 1005333 E

ATOM 17803 N LEU E 420 91125-24507-13809 1005717 E ATOM 17888 CD PRO E 431 92687-14113 -8979 1005175 E

ATOM 17804 CA LEU E 420 92298-24052-13065 1006186 E ATOM 17889 CA PRO E 431 90364-13495 -9068 1005332 E

ATOM 17805 CB LEU E 420 93396-25106-13174 10011536 E ATOM 17890 CB PRO E 431 90776-14281 -10305 10015071 E

ATOM 17806 CG LEU E 420 94494 -25083 -12118 1007431 E ATOM 17891 CG PRO E 431 91893 15107 -9792 10012127 E

ATOM 17807 CDl LEU E 420 93888-25412-10771 1007431 E ATOM 17892 C PRO E 431 89361 -14237 -8231 1004994 E

ATOM 17808 CD2 LEU E 420 95577 -26093 -12482 1007431 E ATOM 17893 O PRO E 431 89703-14928 -7277 1004982 E

ATOM 17809 C LEU E 420 92824 -22703 -13568 1006443 E ATOM 17894 N VAL E 432 88108-14057 -8613 1004792 E

ATOM 17810 O LEU E 420 92633 22347 -14730 1006375 E ATOM 17895 CA VAL E 432 86984 -14714 -7994 1005030 E

ATOM 17811 N VAL E 421 93485-21951 -12691 1006891 E ATOM 17896 CB VAL E 432 85996-13682 -7453 1008496 E

ATOM 17812 CA VAL E 421 94034 -20646 -13063 1006742 E ATOM 17897 CGl VAL E 432 85477-12820 -8570 1005704 E

ATOM 17813 CB VAL E 421 93057-19511 -12706 10010125 E ATOM 17898 CG2 VAL E 432 84870 -14371 6777 1005704 E

ATOM 17814 CGl VAL E 421 93692-18163-12969 1005668 E ATOM 17899 C VAL E 432 86382-15498 -9171 1004830 E

ATOM 17815 CG2VALE421 91817-19644-13534 1005668 E ATOM 17900 O VAL E 432 86507-15086-10323 1003866 E

ATOM 17816 C VAL E 421 95379 -20358-12399 1006968 E ATOM 17901 N CYS E 433 85748 -16630 -8909 1005905 E

ATOM 17817 O VAL E 421 95552-20593-11211 1006528 E ATOM 17902 CA CYS E 433 85196-17415-10004 1005493 E

ATOM 17818 N ARG E 422 96322-19840-13184 1008555 E ATOM 17903 C CYS E 433 83732 -17102 -10258 1005257 E

ATOM 17819 CA ARG E 422 97664-19505-12705 1008768 E ATOM 17904 O CYS E 433 82908-17193 -9348 1005331 E

ATOM 17820 CB ARG E 422 98633-19484-13886 10014951 E ATOM 17905 CB CYS E 433 85369 -18912 -9710 10014601 E

ATOM 17821 CG ARG E 422 99844-20380-13730 10011010 E ATOM 17906 SG CYS E 433 84854-20030-11057 1009312 E

ATOM 17822 CD ARG E 422 100894-19772-12824 10011010 E ATOM 17907 N VAL E 434 83415-16707-11490 1004805 E

ATOM 17823 NE ARG E 422 102110-20582-12813 10011010 E ATOM 17908 CA VAL E 434 82029-16432-11873 1004404 E

ATOM 17824 CZ ARG E 422 103252-20213-12241 10011010 E ATOM 17909 CB VAL E 434 81890-15113-12650 1005728 E

ATOM 17825 NHl ARG E 422 103341 -19041 -11626 10011010 E ATOM 17910 CGl VAL E 434 80424-14793-12839 1003906 E

ATOM 17826 NH2 ARG E 422 104308-21013-12290 10011010 E ATOM 17911 CG2 VAL E 434 82564-13990-11908 1003906 E

ATOM 17827 C ARG E 422 97644-18134-12047 1008491 E ATOM 17912 C VAL E 434 81568-17580-12775 1005444 E

ATOM 17828 O ARG E 422 97664-17118-12736 1007558 E ATOM 17913 O VAL E 434 82129 17807-13849 1004550 E

ATOM 17829 N THR E 423 97606-18106-10718 10013909 E ATOM 17914 N VAL E 435 80545-18301-12330 1004534 E

ATOM 17830 CA THR E 423 97568-16842 -9978 10014874 E ATOM 17915 CA VAL E 435 80026-19448-13073 1003708 E

ATOM 17831 CB THR E 423 97225-17067 -8477 10020084 E ATOM 17916 CB VAL E 435 79789-20637-12109 1005876 E

ATOM 17832 OGl THR E 423 95987-17777 -8366 10016291 E ATOM 17917 CGl VAL E 435 79033-21759-12799 1003809 E

ATOM 17833 CG2THRE423 97091 -15731 -7747 10016291 E ATOM 17918 CG2 VAL E 435 81112-21 135-11594 1003809 E

ATOM 17834 C THR E 423 98889-16086-10050 10014696 E ATOM 17919 C VAL E 435 78725-19164-13824 1004500 E

ATOM 17835 O THR E 423 99538-15881 -9028 10014545 E ATOM 17920 O VAL E 435 77730-18767-13223 1004559 E

ATOM 17836 N THR E 424 99289 -15674 -11249 10018069 E ATOM 17921 N PHE E 436 78740-19371-15140 1003606 E

ATOM 17837 CA THR E 424 100535-14932-11402 10018069 E ATOM 17922 CA PHE E 436 77549-19156-15954 1003226 E

ATOM 17838 CB THR E 424 100839 -14642-12880 10017066 E ATOM 17923 CB PHE E 436 77893-18375-17217 1007078 E

ATOM 17839 OGl THR E 424 100889-15879-13598 10011647 E ATOM 17924 CG PHE E 436 78395-16993-16951 1004555 E

ATOM 17840 CG2 THR E 424 102179 13932-13023 10011647 E ATOM 17925 CDl PHE E 436 79747-16760-16713 1004555 E

ATOM 17841 C THR E 424 100416-13614-10644 10018069 E ATOM 17926 CD2 PHE E 436 77512-15912-16929 1004555 E

ATOM 17842 O THR E 424 99313-13114-10426 10018069 E ATOM 17927 CEl PHE E 436 80218-15462-16459 1004555 E

ATOM 17843 N SER E 425 101552 -13053 -10244 10014896 E ATOM 17928 CE2PHEE436 77970-14607-16671 1004555 E

ATOM 17844 CA SER E 425 101565-11807 -9487 10014896 E ATOM 17929 CZ PHE E 436 79323-14385-16439 1004555 E

ATOM 17845 CB SER E 425 102938 -11609 -8843 10020084 E ATOM 17930 C PHE E 436 76928-20491 -16333 1004009 E

ATOM 17846 OG SER E 425 102943-10463 -8013 10010227 E ATOM 17931 O PHE E 436 77565-21324-16964 1003947 E

ATOM 17847 C SER E 425 101209-10577-10314 10014896 E ATOM 17932 N HIS E 437 75678 20687-15934 1003747 E

ATOM 17848 O SER E 425 101159 -9468 -9788 10014896 E ATOM 17933 CA HIS E 437 74957-21922-16222 1003854 E

ATOM 17849 N LYS E 426 100960-10774-11604 10017872 E ATOM 17934 CB HIS E 437 75277-22961-15158 1006768 E

ATOM 17850 CA LYS E 426 100612 -9668 -12491 10017872 E ATOM 17935 CG HIS E 437 74594-24265-15381 1004405 E

ATOM 17851 CB LYS E 426 100333-10190-13901 10018131 E ATOM 17936 CD2 HIS E 437 73459 -24781 -14854 1004405 E

ATOM 17852 CG LYS E 426 101422-11073-14469 10012561 E ATOM 17937 NDl HIS E 437 75054 -25196 -16285 1004405 E

ATOM 17853 CD LYS E 426 100975-11690-15781 10012561 E ATOM 17938 CEl HIS E 437 74234 -26232 -16307 1004405 E

ATOM 17854 CE LYS E 426 101989-12692-16294 10012561 E ATOM 17939 NE2HISE437 73257 -26005 -15448 1004405 E

ATOM 17855 NZ LYS E 426 101527-13316-17559 10012561 E ATOM 17940 C HIS E 437 73454 -21639 -16235 1004285 E

ATOM 17856 C LYS E 426 99378 -8926 -11987 10017872 E ATOM 17941 O HIS E 437 73003 -20647 -15676 1004507 E

ATOM 17857 O LYS E 426 99305 -7699-12059 10017872 E ATOM 17942 N ASP E 438 72677-22504-16873 1004307 E

ATOM 17858 N MET E 427 98411 -9685-11479 10015739 E ATOM 17943 CA ASP E 438 71231-22308-16946 1004498 E

ATOM 17859 CA MET E 427 97163 -9124-10973 10015739 E ATOM 17944 CB ASP E 438 70577 -23476 -17687 1008518 E

ATOM 17860 CB MET E 427 96177-10250-10667 10014386 E ATOM 17945 CG ASP E 438 70606 -23288 -19194 1005614 E 65251/C766

ATOM 17946 ODl ASP E 438 71459 -22503 -19675 1005614 E ATOM 18031 OEl GLU E 449 93839-17645 0369 10012195 E ATOM 17947 OD2ASPE438 69784 23924 19896 1005614 E ATOM 18032 OE2GLUE449 96038-17591 0449 10012195 E ATOM 17948 C ASP E 438 70617 -22120 -15567 1004632 E ATOM 18033 C GLU E 449 93998-22297 0395 10015054 E ATOM 17949 O ASP E 438 69820-21208-15365 1004988 E ATOM 18034 O GLU E 449 94781 -23235 0536 10015054 E ATOM 17950 N THR E 439 70967-22990-14625 1007846 E ATOM 18035 N GLY E 450 92692-22445 0215 1008675 E ATOM 17951 CA THR E 439 70481 -22849-13259 1007581 E ATOM 18036 CA GLY E 450 92046-23741 0186 1008675 E ATOM 17952 CB THR E 439 70673-24150-12485 1006754 E ATOM 18037 C GLY E 450 90669 -23523 0769 1008675 E ATOM 17953 OGl THR E 439 72069 -24453 -12410 1005335 E ATOM 18038 O GLY E 450 89947 -24471 1087 1008675 E ATOM 17954 CG2 THR E 439 69975 -25296 -13204 1005335 E ATOM 18039 N CYS E 451 90311-22250 0900 10016280 E ATOM 17955 C THR E 439 71438-21774-12755 1008158 E ATOM 18040 CA CYS E 451 89030-21859 1462 10016280 E ATOM 17956 O THR E 439 72589-21752-13166 1008192 E ATOM 18041 CB CYS E 451 87889-22402 0625 10016653 E ATOM 17957 N LEU E 440 70987 -20881 -U 887 1007568 E ATOM 18042 SG CYS E 451 87817 -21639 -1009 10016653 E ATOM 17958 CA LEU E 440 71845-19786-11414 1007770 E ATOM 18043 C CYS E 451 88918-22408 2862 10016280 E ATOM 17959 CB LEU E 440 72984 -20287 -10477 1007885 E ATOM 18044 O CYS E 451 87936-23134 3122 10016280 E ATOM 17960 CG LEU E 440 74205-21241-10611 1005885 E ATOM 18045 OXT CYS E 451 89816-22105 3672 10013890 E ATOM 17961 CDl LEU E 440 73713 -22644 -10756 1005885 E ATOM 18046 CB ARG F 1 71762 17988-13763 10016020 F ATOM 17962 CD2 LEU E 440 75141 -20886 -11744 1005885 E ATOM 18047 CG ARG F 1 70244 18165-13581 10016020 F ATOM 17963 C LEU E 440 72445-18979 12570 1008765 E ATOM 18048 CD ARG F 1 69857 19307-12635 10016020 F ATOM 17964 O LEU E 440 73622-19132-12871 1008587 E ATOM 18049 NE ARG F 6962920576-13331 10016020 F ATOM 17965 N GLU E 441 71639-18115-13202 1004875 E ATOM 18050 CZ ARG F 1 68652 20794-14212 10016020 F ATOM 17966 CA GLUE441 72087 -17295 -14347 1004875 E ATOM 18051 NHl ARG F 1 67794 19830-14519 10016020 F ATOM 17967 CB GLU E 441 71240-16026 -14446 10020084 E ATOM 18052 NH2ARGF 1 6853421981-14794 10016020 F ATOM 17968 CG GLU E 441 69777-16295-14764 10013656 E ATOM 18053 C ARGF 1 71879 19602-15693 10020084 F ATOM 17969 CD GLU E 441 68993-15019-15016 10013656 E ATOM 18054 O ARGF 1 7079920191-15713 10020084 F ATOM 17970 OEl GLU E 441 68966-14147-14120 10013656 E ATOM 18055 N ARGF 1 7253620313-13398 10020084 F ATOM 17971 OE2GLUE441 68404-14888-16112 10013656 E ATOM 18056 CA ARG F 1 72519 19181 -14367 10020084 F ATOM 17972 C GLU E 441 73583-16923-14336 1004875 E ATOM 18057 N THRF 2 72554 19304-16800 10020081 F ATOM 17973 O GLU E 441 74263-17016-15361 1004875 E ATOM 18058 CA THR F 2 72051 19658-18127 10020081 F ATOM 17974 N ALA E 442 74090-16513-13176 1005567 E ATOM 18059 CB THR F 2 73181 19609-19190 10013373 F ATOM 17975 CA ALA E 442 75496-16159-13040 1005389 E ATOM 18060 OGl THRF 2 7426420456-18787 10013247 F ATOM 17976 CB ALA E 442 75802-14909-13843 1003049 E ATOM 18061 CG2THRF 2 72655 20060 -20556 10013562 F ATOM 17977 C ALA E 442 75830-15921 -11584 1004988 E ATOM 18062 C THRF 2 70955 18700-18588 10020081 F ATOM 17978 O ALA E 442 75433-14905-11024 1004729 E ATOM 18063 O THRF 2 71236 17531 -18860 10020081 F ATOM 17979 N GLN E 443 76553-16851-10964 1005928 E ATOM 18064 N PROF 3 69690 19166-18669 10020084 F ATOM 17980 CA GLN E 443 76933-16702 -9558 1006256 E ATOM 18065 CD PRO F 3 6905620438-18268 1008585 F ATOM 17981 CB GLN E 443 76473-17903 -8738 1007866 E ATOM 18066 CA PRO F 3 68684 18205-19127 10020084 F ATOM 17982 CG GLN E 443 75097 -17739 -8141 1006189 E ATOM 18067 CB PROF 3 67463 19088-19391 1008409 F ATOM 17983 CD GLN E 443 74869-18680 -6977 1006189 E ATOM 18068 CG PROF 3 67556 20083-18271 1008396 F ATOM 17984 OEl GLN E 443 75682-18744 -6045 1006189 E ATOM 18069 C PROF 3 69225 17501 -20375 10020084 F ATOM 17985 NE2 GLN E 443 73757 19414 7016 I 006189 E ATOM 18070 O PROF 3 68976 16312-20580 10020084 F ATOM 17986 C GLN E 443 78428-16512 -9365 1006473 E ATOM 18071 N SERF 4 69987 18246-21181 I 0012150 F ATOM 17987 O GLN E 443 79238-17003-10155 1006579 E ATOM 18072 CA SERF 4 70624 17720-22390 10011807 F ATOM 17988 N VAL E 444 78788 15790 -8310 1004724 E ATOM 18073 CB SERF 4 69731 16694-23099 10012432 F ATOM 17989 CA VAL E 444 80191 -15531 -8013 1004439 E ATOM 18074 OG SERF 4 68771 17326-23925 10012627 F ATOM 17990 CB VAL E 444 80407-14041 -7659 1005741 E ATOM 18075 C SERF 4 71017 18784-23406 10011841 F ATOM 17991 CGl VAL E 444 81882-13685 -7742 1004971 E ATOM 18076 O SERF 4 72009 18612-24116 10011856 F ATOM 17992 CG2 VALE444 79616-13170 -8597 1004971 E ATOM 18077 N ASPF 5 70241 19868 23469 1007684 F ATOM 17993 C VALE444 80641-16412 -6844 1004821 E ATOM 18078 CA ASPF 5 7046220964 -24423 1007695 F ATOM 17994 O VAL E 444 79885-16633 -5901 1005047 E ATOM 18079 CB ASP F 5 7186720865-25039 10012680 F ATOM 17995 N TYR E 445 81865-16927 -6918 1004227 E ATOM 18080 CG ASPF 5 72138 21930-26077 10012680 F ATOM 17996 CA TYR E 445 82398-17786 -5868 1004134 E ATOM 18081 ODlASPF 5 7317421824 -26767 10012680 F ATOM 17997 CB TYR E 445 82358-19241 -6310 1007376 E ATOM 18082 OD2ASPF 5 7133022872 -26203 10012536 F ATOM 17998 CG TYR E 445 80963-19709 -6627 1004618 E ATOM 18083 C ASPF 5 6938920902 -25536 1007445 F ATOM 17999 CDl TYR E 445 80439-19587 -7918 1004618 E ATOM 18084 O ASPF 5 6910021903-26195 1007796 F ATOM 18000 CEl TYR E 445 79139-20035 -8214 1004618 E ATOM 18085 N LYSF 6 68798 19720 -25724 1005461 F ATOM 18001 CD2 TYR E 445 80162 -20274 -5640 1004618 E ATOM CA LYSF 6 67764 19482-26742 1005099 F ATOM 18002 CE2TYRE445 78868-20719 -5917 1004618 E ATOM 18087 CB LYSF 6 67539 17990-26951 1005964 F ATOM 18003 CZ TYR E 445 78361-20605 -7201 1004618 E ATOM CG LYSF 6 68631 17196-27623 1006605 F ATOM 18004 OH TYR E 445 77102-21096 7474 1004618 E ATOM 18089 CD LYSF 6 68248 15714 -27574 1006966 F ATOM 18005 C TYR E 445 83817 -17370 -5544 1004280 E ATOM 18090 CE LYS F 6 69157 14855-28431 1007293 F ATOM 18006 O TYR E 445 84597 -17089 -6452 1004566 E ATOM 18091 NZ LYSF 6 69028 15213-29870 1007412 F ATOM 18007 N THR E 446 84153 17357 -4252 1005031 E ATOM 18092 C LYSF 6 66418 20027-26336 1004632 F ATOM 18008 CA THR E 446 85472-16917 -3813 1005729 E ATOM 18093 O LYSF 6 65988 19808-25210 1005020 F ATOM 18009 CB THR E 446 85321-15699 -2895 1005550 E ATOM 18094 N PROF 7 6572620748 -27238 1004347 F ATOM 18010 OGl THR E 446 84471 -16046 -1798 1004365 E ATOM 18095 CD PROF 7 66111 21348 -28522 1003530 F ATOM 18011 CG2THRE446 84696 -14554 -3626 1004365 E ATOM 18096 CA PROF 7 64412 21244-26822 1004151 F ATOM 18012 C THR E 446 86382-17915 -3087 006709 E ATOM 18097 CB PROF 7 6394622070 -28024 1003730 F ATOM 18013 O THR E 446 86256-19131 -3231 007076 E ATOM 18098 CG PROF 7 6476721589 -29148 1003617 F ATOM 18014 N CYS E 447 87305-17323 -2319 009251 E ATOM 18099 C PROF 7 63533 20023 26543 1003957 F ATOM 18015 CA CYS E 447 88328-17944 -1466 1009349 E ATOM 18100 O PROF 7 63497 19076-27319 1004058 F ATOM 18016 C CYS E 447 89451 -18788 -2061 1009352 E ATOM 18101 N VALF 8 6284420037-25416 1003587 F ATOM 18017 O CYS E 447 89265-19557 -2998 1009038 E ATOM 18102 CA VALF 8 62026 18902-25038 1003703 F ATOM 18018 CB CYS E 447 87676-18709 -0302 10012193 E ATOM 18103 CB VALF 8 62879 17864-24249 1003719 F ATOM 18019 SG CYS E 447 86565 -20077 -0738 10010746 E ATOM 18104 CGlVALF 8 63510 18534-23034 1003777 F ATOM 18020 N SER E 448 90635 -18607 -1482 10019489 E ATOM 18105 CG2VALF 8 62024 16669 -23822 1003989 F ATOM 18021 CA SER E 448 91840-19315 -1887 10019489 E ATOM 18106 C VALF 8 60868 19336-24163 1003953 F ATOM 18022 CB SER E 448 92835 -18347 -2523 10020084 E ATOM 18107 O VALF 8 60882 20426 -23574 1003877 F ATOM 18023 OG SER E 448 92271 -17720 -3661 10020084 E ATOM 18108 N ALAF 9 59867 18476-24060 1003671 F ATOM 18024 C SER E 448 92465-19972 -0661 10019489 E ATOM 18109 CA ALAF 9 58725 18794 -23230 1004295 F ATOM 18025 O SER E 448 91767-20250 0315 10019489 E ATOM 18110 CB ALAF 9 57915 19920-23858 1003982 F ATOM 18026 N GLU E 449 93779 20195 -0700 10015054 E ATOM 18111 C ALAF 9 57853 17583-23033 1004393 F ATOM 18027 CA GLU E 449 94479-20856 0398 10015054 E ATOM 18112 O ALAF 9 57608 16815-23960 1004191 F ATOM 1S028 CB GLU E 449 94134-20207 1743 10012195 E ATOM 18113 N HIS F 10 57403 17402-21806 1003365 F ATOM 18029 CG GLU E 449 94904-18939 2045 10012195 E ATOM 18114 CA HISF 10 56514 16307-21485 1003452 F ATOM 18030 CD GLU E 449 94929-17990 0870 10012195 E ATOM 18115 CB HISF 10 57254 15147 20813 1003010 F 65251/C766

ATOM 18116 CG HISF 10 56363 13988-20478 1003159 F ATOM 18201 N GLN F 22 43673 20586-19813 1005501 F

ATOM 18117 CD2 HIS F 10 55753 13633-19319 1002932 F ATOM 18202 CA GLN F 22 4466721645 -19707 1005961 F

ATOM 18118 NDl HIS F 10 55946 13073-21425 1003173 F ATOM 18203 CB GLN F 22 4421522629-18630 1007286 F

ATOM 18119 CE: I HISF 10 55117 12208-20862 I 003208 F ATOM 18204 CG GLN F 22 45213 23704-18269 1007963 F

ATOM 18120 NE2 HIS F 10 54983 12526-19586 1002956 F ATOM 18205 CD GLN F 22 4482424435-16998 1008585 F

ATOM 1S121 C HISF 10 55538 16933 -20508 1003273 F ATOM 18206 OEl GLN F 22 4558725243-16475 1009108 F

ATOM 18122 O HISF 10 55828 17068-19315 1003089 F ATOM 18207 NE2 GLN F 22 43631 24151-16494 1008661 F

ATOM 18123 N VALF 11 54391 17350-21017 1005277 F ATOM 18208 C GLN F 22 46032 21035-19363 1005700 F

ATOM 18124 CA VALF 11 53408 17981 -20164 1005535 F ATOM 18209 O GLN F 22 46158 20275-18400 1005595 F

ATOM 18125 CB VALF 11 52805 19233-20832 1005225 F ATOM 18210 N TRP F 23 4705021364-20153 1005496 F

ATOM 18126 CGl VALF : 11 53910 20244-21080 1004831 F ATOM 18211 CA TRP F 23 4838820823 -19930 1004884 F

ATOM 18127 CG2 VAL F • 11 52111 18862-22138 1005423 F ATOM 18212 CB TRP F 23 49158 20707 -21259 1003958 F

ATOM 18128 C VALF 11 52331 16985-19830 1005396 F ATOM 18213 CG TRP F 23 48479 19918-22328 1004010 F

ATOM 18129 O VALF 11 52099 16034-20577 1005097 F ATOM 18214 CD2 TRP F 23 48237 18507-22337 1003821 F

ATOM 18130 N VALF 12 51679 17206-18697 1005575 F ATOM 18215 CE2 TRP F 23 47560 18208 23539 1003983 F

ATOM 18131 CA VALF 12 50652 16297-18240 1005392 F ATOM 18216 CE3TRPF 23 48526 17467 21449 1003790 F

ATOM 18132 CB VALF 12 51149 15593-16976 1004725 F ATOM 18217 CDl TRP F 23 4796020403 -23493 1003957 F

ATOM 18133 CGl VAL F ^; 12 51113 16562-15801 1004105 F ATOM 18218 NEl TRP F 23 47408 19382-24226 1003866 F

ATOM 18134 CG2 VAL E ^; 12 50347 14349-16723 1005072 F ATOM 18219 CZ2 TRP F 23 47164 16913-23874 1004189 F

ATOM 18135 C VALF 12 49352 17057-17983 1005188 F ATOM 18220 CZ3 TRP F 23 48130 16172 -21784 1004234 F

ATOM 18136 O VALF 12 49360 18278-17847 1005172 F ATOM 18221 CH2 TRP F 23 47456 15912-22987 1004015 F

ATOM 18137 N ALAF 13 48241 16331 -17935 1004872 F ATOM 18222 C TRPF 23 4923721660-18982 1004934 F

ATOM 18138 CA ALAF 13 46923 16929-17722 1004839 F ATOM 18223 O TRP F 23 49232 22884 -19058 1005062 F

ATOM 18139 CB ALAF 13 45827 15946-18118 1002620 F ATOM 18224 N LEU F 24 49972 20999-18093 1004514 F

ATOM 18140 C ALAF 13 46687 17389-16295 1005237 F ATOM 18225 CA LEU F 24 5087021713-17192 1004283 F

ATOM 18141 O ALAF 13 47063 16700-15341 1004988 ATOM 18226 CB LEUF 24 50379 21726-15744 1006141 F

ATOM 18142 N ASNF 14 46047 18554-16167 1004944 ATOM 18227 CG LEU F 24 4894421401-15381 1006214 F

ATOM 18143 CA ASNF 14 45717 19153-14872 1005056 F ATOM 18228 CDl LEU F 24 48726 19919-15553 1006376 F

ATOM 18144 CB ASNF 14 4551820649-15046 1006525 F ATOM 18229 CD2 LEU F 24 48693 21801 -13944 1005725 F

ATOM 18145 CG ASNF 14 4519021343 13749 1006724 F ATOM 18230 C LEU F 24 52221 21042-17218 1004969 F

ATOM 18146 ODl ASN F • 14 44928 22546 -13733 1006682 F ATOM 18231 O LEU F 24 52347 19873-17596 1004667 F

ATOM 18147 ND2 ASN F ^■ 14 45208 20595 -12650 1006936 F ATOM 18232 N ASN F 25 53231 21790-16805 1004839 F

ATOM 18148 C ASNF 14 44434 18533-14328 1005344 F ATOM 18233 CA ASN F 25 54581 21275-16759 1004983 F

ATOM 18149 O ASNF 14 43362 18718-14896 1005396 F ATOM 18234 CB ASN F 25 5545722071 -17708 1004701 F

ATOM 18150 N PROF 15 44523 17799-13210 1005659 F ATOM 18235 CG ASNF 25 55733 23451 -17194 1004858 F

ATOM 18151 CD PROF 15 45710 17511 -12387 1005272 F ATOM 18236 ODl ASN F 25 56875 23793-16871 1005257 F

ATOM 18152 CA PROF 15 43327 17166-12639 1006019 F ATOM 18237 ND2 ASN F 25 5468024256-17092 1004498 F

ATOM 18153 CB PROF 15 43898 16171 -11619 1005706 F ATOM 18238 C ASN F 25 55138 21404 -15333 1005036 F

ATOM 18154 CG PROF 15 45404 16129-11903 1005533 F ATOM 18239 O ASN F 25 56263 20987 -15052 1005272 F

ATOM 18155 C PROF 15 42391 18166-11975 1006140 F ATOM 18240 N ARG F 26 5435021981 -14435 1006037 F

ATOM 18156 O PROF 15 41202 17894-11805 1006343 F ATOM 18241 CA ARG F 26 54793 22176 -13064 1006165 F

ATOM 18157 N GLNF 16 42940 19320-11606 10011268 F ATOM 18242 CB ARG F 26 5413823430-12488 I 006156 F

ATOM 18158 CA GLNF 16 4218020372-10938 10011163 F ATOM 18243 CG ARG F 26 5263023450-12558 1006247 F

ATOM 18159 CB GLNF 16 4314921308-10197 10012671 F ATOM 18244 CD ARGF 26 52081 24566 -11695 1006653 F

ATOM 18160 CG GLNF 16 4252422142 -9084 10012964 F ATOM 18245 NE ARG F 26 5062424619-11737 1006767 F

ATOM 18161 CD GLNF 16 4190221286 -7997 10013143 F ATOM 18246 CZ ARG F 26 49929 25212-12701 1006823 F

ATOM 18162 OE 1 GLNf ^' 16 4248420288 -7572 10013355 F ATOM 18247 NHl ARG F 26 5055825815-13708 1006871 F

ATOM 18163 NE2 GLN P ^r 16 40718 21679 -7532 10013008 F ATOM 18248 NH2 ARG F 26 48605 25196-12663 1006726 F

ATOM 18164 C GLNF 16 4131221177 11915 10010830 F ATOM 18249 C ARG F 26 5452020996-12141 1005971 F

ATOM 18165 O GLNF 16 40641 22130 -11520 1 OOIOS 87 F ATOM 18250 O ARG F 26 54021 21173-11032 1005942 F

ATOM 18166 N ALAF 17 4132420794-13187 10011315 F ATOM 18251 N ARG F 27 54854 19792 -12584 1005908 F

ATOM 18167 CA ALAF 17 4053021496 14191 10011691 F ATOM 18252 CA ARG F 27 54613 18623-11760 1006001 F

ATOM 18168 CB ALAF 17 4143622066-15271 1005821 F ATOM 18253 CB ARG F 27 53383 17861-12259 1004273 F

ATOM 18169 C ALAF 17 3950420561 -14811 10012141 F ATOM 18254 CG ARG F 27 52103 18604-12068 1004415 F

ATOM 18170 O ALAF 17 3954620278-16008 10012305 F ATOM 18255 CD ARG F 27 51980 19049-10630 1004652 F

ATOM 18171 N GLUF 18 3858220085-13984 1009247 F ATOM 18256 NE ARG F 27 50803 19887-10401 1004991 F

ATOM 18172 CA GLUF 18 37535 19175-14431 I 009447 F ATOM 18257 CZ ARG F 27 49545 19473-10541 1005352 F

ATOM 18173 CB GLUF 18 36499 18987-13323 10015364 F ATOM 18258 NHl ARG F 27 48538 20314-10309 1005439 F

ATOM 18174 CG GLUF 18 35793 20273 -12920 10015364 F ATOM 18259 NH2 ARG F 27 49299 18216-10911 1005175 F

ATOM 18175 CD GLUF 18 3466920040-11927 10015364 F ATOM 18260 C ARG F 27 55794 17675-11674 1006047 F

ATOM 18176 OEl GLU I ^; 18 33712 19314-12271 10015364 F ATOM 18261 O ARG F 27 56819 17869-12333 1006061 F

ATOM 18177 OE2 GLU F • 18 34739 20582-10803 10015364 F ATOM 18262 N ALA F 28 55610 16648-10847 1008246 F

ATOM 18178 C GLUF 18 36830 19662-15695 1009413 F ATOM 18263 CA ALA F 28 56592 15607-10577 1008136 F

ATOM 18179 O GLUF 18 3669620868 -15932 1009374 F ATOM 18264 CB ALA F 28 55874 14321-10183 10011083 F

ATOM 18180 N GLYF 19 36389 18704-16504 1008448 F ATOM 18265 C ALAF 28 57580 15310-11691 1008102 F

ATOM 18181 CA GLYF 19 35677 19022-17727 1008197 F ATOM 18266 O ALAF 28 58679 15854-11721 1008204 F

ATOM 18182 C GLYF 19 36506 19461 -18918 1008047 F ATOM 18267 N ASNF 29 57195 14439-12609 1004903 F

ATOM 18183 O GLYF 19 35978 19588-20021 1008048 F ATOM 18268 CA ASN F 29 58098 14069-13681 1004820 F

ATOM 18184 N GLNF 20 37798 19696-18716 I 008619 F ATOM 18269 CB ASN F 29 58196 12548-13731 1005394 F

ATOM 18185 CA GLNF 20 38655 20128-19815 1008176 F ATOM 18270 CG ASN F 29 58779 11967-12455 1005400 F

ATOM 18186 CB GLNF 20 3878221646 -19793 10010323 F ATOM 18271 ODl ASN F 29 59994 11972-12251 1005986 F

ATOM 18187 CG GLNF 20 3924722181 -18460 10010421 F ATOM 18272 ND2 ASN F 29 57912 11482-11580 1005101 F

ATOM 18188 CD GLNF 20 3930023687 -18435 10010397 F ATOM 18273 C ASNF 29 57669 14630-15028 1004654 F

ATOM 18189 OEl GLN I : 20 3828824350 -18646 I 0010362 F ATOM 18274 O ASN F 29 57406 13881-15973 1004426 F

ATOM 18190 NE2 GLN E 40483 24240-18178 10010342 F ATOM 18275 N ALAF 30 57606 15955 15106 1004105 F

ATOM 18191 C GLNF 20 40040 19485 -19776 1007650 F ATOM 18276 CA ALA F 30 57207 16626-16330 1003587 F

ATOM 18192 O GLNF 20 40415 18830-18804 1007521 F ATOM 18277 CB ALA F 30 55994 17503-16071 1004129 F

ATOM 18193 N LEUF 21 40796 19670 -20848 1005949 F ATOM 18278 C ALAF 30 58378 17465-16846 1003727 F

ATOM 18194 CA LEUF 21 42134 19107-20935 1005595 F ATOM 18279 O ALAF 30 59369 17675-16130 1004142 F

ATOM 18195 CB LEUF 21 42262 18229 -22188 1005725 F ATOM 18280 N LEUF 31 58263 17940-18083 1005052 F

ATOM 18196 CG LEUF 21 43624 17591-22495 I 005603 F ATOM 18281 CA LEU F 31 59327 18721 -18685 1004999 F

ATOM 18197 CDl LEU f ^; 21 44185 16901 -21263 1005333 F ATOM 18282 CB LEU F 31 60250 17810-19487 1004334 F

ATOM 18198 CD2 LEU F ^; 21 43458 16606-23635 1005807 F ATOM 18283 CG LEU F 31 61200 16846-18798 1004622 F

ATOM 18199 C LEUF 21 43163 20216 20980 1005456 F ATOM 18284 CDl LEUF 31 61739 15852-19813 1004384 F

ATOM 18200 O LEUF 21 43491 20726 -22049 1004988 F ATOM 18285 CD2LEUF 31 62316 17628-18166 1004569 F 65251/C766

ATOM 18286 C LEUF 31 58834 19812-19618 1004925 F ATOM 18371 C GLN F 42 51459 24444 -26968 1005089 F ATOM 18287 O LEUF 31 57795 19673-20269 1005006 F ATOM 18372 O GLN F 42 51957 25395 -26375 1005123 F

ATOM 18288 N LEUF 32 59621 20882-19690 1004188 F ATOM 18373 N LEU F 43 52182 23446 -27458 1004510 F

ATOM 18289 CA LEU F 32 5935922029 -20552 1004167 F ATOM 18374 CA LEU F 43 53624 23457 -27337 1004368 F

ATOM 18290 CB LEUF 32 58231 22906-19994 1004413 F ATOM 18375 CB LEU F 43 54164 22031 -27334 1003166 F

ATOM 18291 CG LEUF 32 5788524049-20955 1004271 F ATOM 18376 CG LEU F 43 53721 21215 26117 1003782 F

ATOM 18292 CDl LEU F 32 5727423471 -22224 1004169 ATOM 18377 CDl LEU F 43 54125 19752-26278 1003791 F

ATOM 18293 CD2 LEU F 32 5692725019-20292 1004303 F ATOM 18378 CD2 LEU F 43 54330 21811-24872 1003421 F

ATOM 18294 C LEUF 32 60671 22809-20560 1004131 F ATOM 18379 C LEU F 43 54153 24221 -28531 1004570 F

ATOM 18295 O LEUF 32 6083223793-19834 1004718 F ATOM 18380 O LEU F 43 53657 24052 -29638 1004232 F ATOM 18296 N ALAF 33 6160522374-21396 1003967 F ATOM 18381 N VAL F 44 55147 25072 -28319 1003750 F

ATOM 18297 CA ALAF 33 62911 23010-21419 1004019 F ATOM 18382 CA VAL F 44 55695 25837 -29422 1003718 F

ATOM 18298 CB ALA F 33 6387022174 -20608 1002454 F ATOM 18383 CB VAL F 44 55527 27343 -29184 1003194 F

ATOM 18299 C ALA F 33 63553 23313-22766 1004198 F ATOM 18384 CGl VALF 44 55942 28121-30419 1003313 F

ATOM 18300 O ALAF 33 6307522916-23839 1004616 F ATOM 18385 CG2 VAL F 44 54085 27644 -28825 1002655 F

ATOM 18301 N ASNF 34 64671 24021-22667 1004857 F ATOM 18386 C VAL F 44 57168 25520-29644 1003619 F

ATOM 18302 CA ASN F 34 6546824388 -23812 1004576 F ATOM 18387 O VAL F 44 58009 25730 -28764 1003723 F

ATOM 18303 CB ASNF 34 6620223161 24325 1005885 F ATOM 18388 N VAL F 45 57471 25015-30835 1003664 F

ATOM 18304 CG ASNF 34 6708022554-23273 1006277 F ATOM 18389 CA VAL F 45 58824 24641 -31207 1004238 F

ATOM 18305 ODl ASNF 34 67871 23252-22642 1006525 F ATOM 18390 CB VAL F 45 58795 23814 -32506 1007225 F

ATOM 18306 ND2 ASN F 34 6694821252 -23065 1005818 F ATOM 18391 CGl VALF 45 60193 23654-33063 1007482 F ATOM 18307 C ASNF 34 64747 25075-24954 1004651 F ATOM 18392 CG2 VAL F 45 58189 22453 -32224 1007565 F

ATOM 18308 O ASNF 34 6500024787-26127 1004905 F ATOM 18393 C VAL F 45 59747 25857-31365 1004417 F

ATOM 18309 N GLY F 35 6384725988 -24619 1005150 F ATOM 18394 O VAL F 45 59397 26843 -31999 1004362 F

ATOM 18310 CA GLY F 35 6318426729-25664 1004609 F ATOM 18395 N PRO F 46 60950 25790-30781 1005120 F

ATOM 18311 C GLYF 35 61732 26460-25947 1004644 F ATOM 18396 CD PROF 46 61354 24800 -29762 1003554 F

ATOM 18312 O GLYF 35 6100527393-26308 1004793 F ATOM 18397 CA PRO F 46 61926 26881 -30850 1005005 F

ATOM 18313 N VALF 36 6128025218-25815 1004365 F ATOM 18398 CB PRO F 46 62626 26783 -29512 1003490 F

ATOM 18314 CA VAL F 36 5988024995 -26126 1004498 F ATOM 18399 CG PROF 46 62734 25305 -29342 1003560 F

ATOM 18315 CB VALF 36 5955223480-26297 1004741 F ATOM 18400 C PRO F 46 62931 26839-31987 1005349 F

ATOM 18316 CGl VALF 36 6072422651 -25882 1004544 F ATOM 18401 O PRO F 46 63714 27773 -32134 1005595 F

ATOM 18317 CG2VALF 36 5829423111-25532 1004781 F ATOM 18402 N SER F 47 62938 25768 -32780 1006554 F ATOM 18318 C VALF 36 59012 25678-25073 1004913 F ATOM 18403 CA SER F 47 63905 25678 -33883 1006266 F

ATOM 18319 0 VALF 36 5931725651 -23881 1005009 F ATOM 18404 CB SER F 47 65292 25372 -33324 1006349 F

ATOM 18320 N GLUF 37 5794526322-25542 1004727 ATOM 18405 OG SERF 47 65287 24131 -32638 1006470 F

ATOM 18321 CA GLUF 37 5703227044-24667 1004987 F ATOM 18406 C SER F 47 63567 24645 -34956 1005935 F

ATOM 18322 CB GLUF 37 5694028498 25116 1006100 F ATOM 18407 O SER F 47 62820 23699 -34706 1005649 F

ATOM 18323 CG GLU F 37 5826429031 -25630 1006803 F ATOM 18408 N GLU F 48 64125 24848-36151 1005194 F

ATOM 18324 CD GLUF 37 5813030334-26390 1007100 ATOM 18409 CA GLU F 48 63926 23949 -37289 1005643 F

ATOM 18325 OEl GLUF 37 57068 30552-27019 1007443 F ATOM 18410 CB GLU F 48 64806 24366 -38469 10012488 F

ATOM 18326 OE2 GLU F 37 59095 31131 -26375 1007156 F ATOM 18411 CG GLU F 48 64630 25795 -38959 10012962 F

ATOM 18327 C GLUF 37 55651 26420-24690 1004876 F ATOM 18412 CD GLU F 48 63458 25963 -39908 10013397 F

ATOM 18328 O GLU F 37 55259 25772 -25657 1005122 F ATOM 18413 OEl GLU F 48 62300 25847 -39457 10013571 F

ATOM 18329 N LEU F 38 54931 26600-23595 1005507 F ATOM 18414 OE2 GLU F 48 63700 26208-41 110 10013189 F

ATOM 18330 CA LEU F 38 53581 26095 -23486 1005711 F ATOM 18415 C GLU F 48 64391 22585-36815 1005502 F

ATOM 18331 CB LEUF 38 53391 25367-22161 1005078 F ATOM 18416 O GLU F 48 65262 22497 -35953 1006081 F

ATOM 18332 CG LEU F 38 5201724714 -21964 1004869 F ATOM 18417 N GLY F 49 63821 21517-37357 1004723 F

ATOM 18333 CDl LEUF 38 51635 23915-23214 1004707 F ATOM 18418 CA GLYF 49 64270 20204 -36949 1004489 F

ATOM 18334 CD2 LEU F 38 5203923809 -20726 1004556 F ATOM 18419 C GLY F 49 63280 19065-36981 1004690 F

ATOM 18335 C LEUF 38 52755 27365-23528 1005738 F ATOM 18420 O GLY F 49 62090 19246-37219 1004974 F

ATOM 18336 O LEUF 38 52665 28087-22544 1005099 F ATOM 18421 N LEU F 50 63812 17873-36747 1005276 F

ATOM 18337 N ARGF 39 5216827640-24684 1004465 F ATOM 18422 CA LEU F 50 63043 16646-36701 1005396 F

ATOM 18338 CA ARGF 39 5138828847-24900 1005118 F ATOM 18423 CB LEUF 50 63942 15500-37119 1004086 F

ATOM 18339 CB ARG F 39 52113 29693 -25948 1006547 F ATOM 18424 CG LEUF 50 63666 14744 -38415 1004199 F

ATOM 18340 CG ARG F 39 5160631089 -26118 1007317 F ATOM 18425 CDl LEU F 50 62991 15624-39425 1003880 F

ATOM 18341 CD ARG F 39 5258731892 -26952 1008178 F ATOM 18426 CD2 LEU F 50 64981 14201 -38958 1004238 F

ATOM 18342 NE ARG F 39 52293 33322 -26895 1008831 F ATOM 18427 C LEU F 50 62604 16471 -35247 1005034 F

ATOM 18343 CZ ARGF 39 53121 34270-27320 1008911 F ATOM 18428 O LEUF 50 63421 16568 -34332 1004906 F

ATOM 18344 NHlARGF 39 54298 33943 27837 1008759 F ATOM 18429 N TYRF 51 61318 16227-35020 1004802 F

ATOM 18345 NH2 ARG F 39 52778 35547-27219 1009141 F ATOM 18430 CA TYRF 51 60823 16059-33657 1004667 F

ATOM 18346 C ARG F 39 4996728513 -25355 1005323 F ATOM 18431 CB TYRF 51 59942 17243-33230 1003696 F

ATOM 18347 O ARGF 39 4976627695-26249 1005646 F ATOM 18432 CG TYRF 51 60658 18537-32951 1003706 F

ATOM 18348 N ASP F 40 48981 29139-24729 1005911 F ATOM 18433 CDlTYRF 51 61 170 19318 -33988 1003792 F

ATOM 18349 CA ASP F 40 4758628910 -25083 1005706 F ATOM 18434 CElTYRF 51 61816 20518-33734 1003748 F

ATOM 18350 CB ASPF 40 4725029617-26404 10011199 F ATOM 18435 CD2TYRF 51 60813 18989-31649 1003862 F

ATOM 18351 CG ASPF 40 4757631108-26376 10011413 F ATOM 18436 CE2TYRF 51 61462 20191 31378 1003689 F ATOM 18352 ODl ASP F 40 47091 31811 -25463 10011101 F ATOM 18437 CZ TYRF 51 61962 20954 -32424 1003659 F

ATOM 18353 OD2 ASP F 40 4831631579-27271 10011425 F ATOM 18438 OH TYRF 51 62617 22148 -32149 1003682 F

ATOM 18354 C ASPF 40 4727227418-25197 1005319 F ATOM 18439 C TYRF 51 59992 14809 -33467 1004685 F

ATOM 18355 O ASFF 40 4650227002-26059 1005242 F ATOM 18440 O TYRF 51 59229 14412-34351 1004774 F

ATOM 18356 N ASNF 41 47883 26626-24322 1004865 F ATOM 18441 N LEUF 52 60133 14190-32302 1004023 F

ATOM 18357 CA ASNF 41 4768525175-24251 1004440 F ATOM 18442 CA LEU F 52 59327 13028-31978 1004188 F

ATOM 18358 CB ASN F 41 4620024840 -24139 1005902 F ATOM 18443 CB LEU F 52 60108 12038-31 120 1005850 F

ATOM 18359 CG ASN F 41 4595623514 -23434 1005371 F ATOM 18444 CG LEU F 52 59275 10917-30491 1005439 F

ATOM 18360 ODl ASN F 41 4644623285 -22322 1005505 F ATOM 18445 CDl LEU F 52 58463 10212-31562 1005642 F

ATOM 18361 ND2ASNF 41 4519022638-24071 1004981 F ATOM 18446 CD2LEUF 52 60195 9930 -29787 1004872 F

ATOM 18362 C ASNF 41 48288 24405-25413 1004771 F ATOM 18447 C LEUF 52 58177 13633-31 187 1004341 F ATOM 18363 O ASN F 41 4785623290 25731 1004922 F ATOM 18448 O LEUF 52 58396 14306-30183 1004398 F

ATOM 18364 N GLNF 42 49295 24997-26042 1005408 F ATOM 18449 N ILEF 53 56956 13435-31667 1003904 F

ATOM 18365 CA GLN F 42 4995924360 -27163 1005200 F ATOM 18450 CA ILEF 53 55773 13968-30998 1003564 F

ATOM 18366 CB GLNF 42 4958625064-28457 1004736 F ATOM 18451 CB ILEF 53 54939 14822-31954 1004275 F

ATOM 18367 CG GLNF 42 4809825293-28613 1004945 F ATOM 18452 CG2 ILE F 53 53760 15417-31225 1004339 F

ATOM 18368 CD GLNF 42 47753 26020-29901 1004891 F ATOM 18453 CGl ILE F 53 55799 15926-32545 1004164 F

ATOM 18369 OEl GLN F 42 4836427041 -30237 1004834 F ATOM 18454 CDl ILE F 53 55051 16764-33540 1003746 F

ATOM 18370 NE2 GLN F 42 4676025503 -30626 1005067 F ATOM 18455 C ILEF 53 54911 12809-30521 1003570 F 65251/C766

ATOM 184560 ILEF 53 54755 11815-31230 1003878 F ATOM 18541 SG CYSF 64 28284 1396-22614 10014916 F ATOM 18457 N TYRF 54 54346 12931 -29329 1003830 F ATOM 18542 N PRO F 65 26150 5401 -22501 10011093 F

ATOM 18458 CA TYR F 54 53525 11851 -28806 1003543 F ATOM 18543 CD PRO F 65 27535 5716-22887 10014874 F

ATOM 18459 CB TYRF 54 54426 10761 -28207 1003413 F ATOM 18544 CA PROF 65 25249 6478-22917 10011327 F

ATOM 18460 CG TYRF 54 55211 11229-26999 1003413 F ATOM 18545 CB PROF 65 26192 7486-23577 10015127 F

ATOM 18461 CDl TYRF 54 54658 11 155-25715 1003413 F ATOM 18546 CG PROF 65 27510 7215 22916 10015100 F

ATOM 18462 CEl TYR F 54 55338 11638 -24607 1003413 ATOM 18547 C PRO F 65 24196 5970-23893 10011628 F

ATOM 18463 CD2 TYR F 54 56475 11798-27141 1003413 F ATOM 18548 O PROF 65 23824 4797-23877 10011655 F

ATOM 18464 CE2 TYR F 54 57162 12285 -26038 1003413 F ATOM 18549 N SER F 66 23732 6868-24752 10016281 F

ATOM 18465 CZ TYRF 54 56586 12204-24770 1003413 F ATOM 18550 CA SERF 66 22729 6532-25747 10016641 F ATOM 18466 OH TYRF 54 57237 12688-23656 1003413 F ATOM 18551 CB SERF 66 21742 7689-25899 10015651 F

ATOM 18467 C TYRF 54 52523 12339-27756 1003402 F ATOM 18552 OG SERF 66 20777 7411-26897 10015367 F

ATOM 18468 O TYRF 54 52673 13425-27174 1003287 F ATOM 18553 C SERF 66 23396 6248-27086 10016696 F

ATOM 18469 N SERF 55 51507 11520-27516 1004440 F ATOM 18554 O SERF 66 24615 6376-27224 10016038 F

ATOM 1S470 CA SERF 55 50489 11871 26557 1004418 F ATOM 18555 N THRF 67 22580 5863 -28063 10020084 F

ATOM 18471 CB SERF 55 49599 12973-27119 1005249 F ATOM 18556 CA THRF 67 23032 5550-29417 10020084 F

ATOM 18472 OG SERF 55 48490 13199-26267 1005905 F ATOM 18557 CB THR F 67 22869 6771 -30355 10017192 F

ATOM 18473 C SERF 55 49624 10685-26210 1004716 F ATOM 18558 OGlTHRF 67 21523 7255-30282 10017192 F

ATOM 184740 SER F 55 49445 9772-27021 1004430 F ATOM 18559 CG2 THR F 67 23180 6383-31802 10017192 F

ATOM 18475 N GLNF 56 49089 10695-24993 1006071 F ATOM 18560 C THRF 67 24480 5069 -29502 10020084 F

ATOM 18476 CA GLN F 56 48204 9630 -24570 1006141 F ATOM 18561 O THR F 67 24771 3896-29258 10020084 F ATOM 18477 CB GLNF 56 48929 8566-23755 1004765 F ATOM 18562 N HIS F 68 25384 5982 -29845 10014493 F

ATOM 18478 CG GLNF 56 47992 7411 -23444 1004925 F ATOM 18563 CA HIS F 68 26790 5641 -29986 10014005 F

ATOM 18479 CD GLNF 56 48500 6482-22373 1005237 F ATOM 18564 CB HIS F 68 27057 5196 -31429 10018902 F

ATOM 18480 OEl GLNF 56 48410 6784-21187 1005190 F ATOM 18565 CG HIS F 68 28279 4347 31589 10018902 F

ATOM 18481 NE2 GLN F 56 49039 5339 -227S4 1005548 F ATOM 18566 CD2HISF 68 29405 4532-32317 10018902 F

ATOM 18482 C GLNF 56 47095 10185-23714 1006389 F ATOM 18567 NDl HIS F 68 28424 3127-30963 10018902 F

ATOM 18483 O GLNF 56 47337 11008-22825 1006197 F ATOM 18568 CEl HIS F 68 29587 2599-31297 10018902 F

ATOM 18484 N VAL F 57 45876 9741 -23990 1004950 F ATOM 18569 NE2 HIS F 68 30202 3431 -32118 10018902 F

ATOM 18485 CA VALF 57 44737 10160-23193 1004387 F ATOM 18570 C HIS F 68 27665 6842-29638 10013588 F

ATOM 18486 CB VALF 57 43731 10992-24005 1006148 F ATOM 18571 O HISF 68 27314 7982-29940 10013533 F

ATOM 18487 CGl VAL F 57 44415 12223 -24562 1006268 F ATOM 18572 N VALF 69 28800 6577 -28997 1009493 F ATOM 18488 CG2VALF 57 43134 10154-25113 1005841 F ATOM 18573 CA VALF 69 29740 7626-28612 1009466 F

ATOM 18489 C VAL F 57 44053 8894 -22704 1004648 F ATOM 18574 CB VALF 69 29928 7685-27080 10010960 F

ATOM 184900 VALF 57 44132 7850-23350 1004759 F ATOM 18575 CGl VALF 69 30864 8822-26717 10010936 F

ATOM 18491 N LEU F 58 43402 8978-21552 1005953 F ATOM 18576 CG2VALF 69 28585 7869 26396 10010786 F

ATOM 18492 CA LEUF 58 42701 7825-21012 1005798 F ATOM 18577 C VALF 69 31101 7374-29252 1009425 F

ATOM 18493 CB LEUF 58 43321 7396-19684 1005421 F ATOM 18578 O VAL F 69 31615 6254-29226 1009781 F

ATOM 18494 CG LEUF 58 43176 5925-19293 1005623 F ATOM 18579 N LEU F 70 31675 8422-29833 1008201 F

ATOM 18495 CDl LEU F 58 43332 5804-17783 1005025 F ATOM 18580 CA LEU F 70 32980 8323 -30474 1007723 F

ATOM 18496 CD2 LEU F 58 41828 5390-19722 1005401 F ATOM 18581 CB LEUF 70 32925 8827-31918 1008176 F

ATOM 18497 C LEU F 58 41251 8225-20791 1006095 F ATOM 18582 CG LEU F 70 32130 7997-32922 1008346 F

ATOM 18498 O LEU F 58 40961 9110-19980 1006258 F ATOM 18583 CDl LEU F 70 32290 8618-34306 1007850 F

ATOM 18499 N PHEF 59 40343 7589-21523 1006811 F ATOM 18584 CD2 LEU F 70 32617 6545-32915 1008406 F

ATOM 18500 CA PHEF 59 38923 7888-21384 1006901 F ATOM 18585 C LEU F 70 34014 9133-29718 1007827 F

ATOM 18501 CB PHEF 59 38209 7791 -22728 1005379 F ATOM 18586 O LEU F 70 33771 10277-29340 1007838 F

ATOM 18502 CG PHEF 59 38632 8825-23718 1005028 F ATOM 18587 N LEU F 71 35173 8528-29504 1007130 F

ATOM 18503 CDl PHEF 59 39490 8500-24756 1004872 F ATOM 18588 CA LEUF 71 36267 9181-28809 1007124 F

ATOM 18504 CD2 PHE F 59 38157 10124-23629 1005224 F ATOM 18589 CB LEUF 71 36773 8285-27681 1006553 F

ATOM 1S5O5 CEl PHEF 59 39868 9453-25697 1005464 F ATOM 18590 CG LEU F 71 35746 7909 -26607 1006320 F

ATOM 18506 CE2PHEF 59 38530 11085-24564 1005535 F ATOM 18591 CDl LEU F 71 36364 6939 -25605 1005935 F

ATOM 18507 CZ PHEF 59 39388 10745-25600 1005395 F ATOM 18592 CD2 LEU F 71 35264 9172-25912 1006332 F

ATOM 18508 C PHEF 59 38282 6905-20416 1007312 F ATOM 18593 C LEUF 71 37387 9418-29808 1007527 F

ATOM 18509 0 PHE F 59 38660 5738-20371 1007281 F ATOM 18594 O LEU F 71 37827 8487 -30484 1007476 F

ATOM 18510 N LYS F 60 37315 7388-19642 1008303 F ATOM 18595 N THR F 72 37840 10661 -29914 1005833 F

ATOM 18511 CA LYSF 60 36610 6558-18678 1008438 F ATOM 18596 CA THRF 72 38918 10980-30836 1005576 F

ATOM 18512 CB LYSF 60 37229 6705-17286 1008357 F ATOM 18597 CB THRF 72 38448 11863-32003 1006710 F

ATOM 18513 CG LYSF 60 36492 5940-16198 1008976 F ATOM 18598 OGlTHRF 72 38297 13217-31553 1006963 F

ATOM 18514 CD LYSF 60 37115 6202-14843 1009797 F ATOM 18599 CG2THRF 72 37132 11357-32552 1006482 F

ATOM 18515 CE LYSF 60 36374 5476-13738 10010072 F ATOM 18600 C THRF 72 40048 11713-30131 1005839 F

ATOM 18516 NZ LYSF 60 37037 5701-12424 10010106 F ATOM 18601 O THRF 72 39830 12552 -29253 1005943 F

ATOM 18517 C LYSF 60 35154 6980-18630 1008389 F ATOM 18602 N HIS F 73 41264 11370 -30526 1005757 F

ATOM 18518 O LYSF 60 34840 8170-18640 1008664 F ATOM 18603 CA HIS F 73 42458 11984 -29988 1005802 F

ATOM 18519 N GLY F 61 34266 5999-18581 1009096 F ATOM 18604 CB HIS F 73 43244 10968-29187 1004793 F

ATOM 18520 CA GLYF 61 32854 6306-18522 1009352 F ATOM 18605 CG HIS F 73 44429 11550-28499 1005080 F

ATOM 18521 C GLY F 61 32121 5332-17626 1009522 F ATOM 18606 CD2 HIS F 73 44751 12832 28213 1005256 F ATOM 18522 O GLYF 61 32464 4150-17570 1009839 F ATOM 18607 NDI HIS F 73 45457 10774-28010 1005541 F

ATOM 18523 N GLNF 62 31 120 5834-16912 1009121 F ATOM 18608 CEl HIS F 73 46364 11556-27451 1005395 F

ATOM 18524 CA GLNF 62 30314 5001-16030 1009152 F ATOM 18609 NE2 HIS F 73 45959 12808-27561 1005412 F

ATOM 18525 CB GLNF 62 29766 5833-14870 10013170 F ATOM 18610 C HIS F 73 43249 12390-31216 1005710 F

ATOM 18526 CG GLNF 62 30833 6526-14039 10013583 F ATOM 18611 O HIS F 73 43384 11602-32154 1005296 F

ATOM 18527 CD GLNF 62 31741 5549-13318 10014177 F ATOM 18612 N THR F 74 43763 13612-31236 1005002 F

ATOM 18528 OEl GLN F 62 32412 4730-13944 10014137 F ATOM 18613 CA THRF 74 44506 14043 -32407 1005661 F

ATOM 18529 NE2 GLN F 62 31767 5632 -11993 10014194 F ATOM 18614 CB THR F 74 43516 14458-33564 1005562 F

ATOM 18530 C GLNF 62 29164 4480 16878 1008946 F ATOM 18615 OGl THR F 74 43929 15694-34145 1005813 F

ATOM 18531 O GLN F 62 28401 5266-17438 1009097 F ATOM 18616 CG2THRF 74 42087 14594 -33048 1006045 F

ATOM 18532 N GLY F 63 29050 3160-16989 10012626 F ATOM 18617 C THRF 74 45516 15155-32136 1005546 F ATOM 18533 CA GLYF 63 27982 2583-17788 10012425 F ATOM 18618 O THRF 74 45246 16089-31381 1005104 F

ATOM 18534 C GLYF 63 27980 3147-19197 10012233 F ATOM 18619 N ILE F 75 46695 15028-32741 1004113 F

ATOM 18535 O GLYF 63 28927 3826-19593 10012037 F ATOM 18620 CA ILEF 75 47744 16029 -32592 1004243 F

ATOM 18536 N CYS F 64 26916 2892-19954 10014497 F ATOM 18621 CB ILEF 75 49116 15372-32347 1004485 F

ATOM 18537 CA CYSF 64 26844 3380-21327 10014921 F ATOM 18622 CG2 ILE F 75 50208 16430-32308 1004434 F

ATOM 18538 C CYSF 64 25787 4426-21653 10015530 F ATOM 18623 CGl ILE F 75 49079 14599-31031 1004201 F

ATOM 18539 O CYSF 64 24663 4376-21 158 10015821 F ATOM 18624 CDl ILE F 75 50401 13965-30660 1004530 F

ATOM 18540 CB CYSF 64 26693 2204-22286 10014795 F ATOM 18625 C ILE F 75 47793 16843-33878 1004557 F 65251/C766

ATOM 18626 O ILEF 75 47958 16294-34976 1004234 F ATOM 18711 CG2VALF 86 48932 20555 -40586 1004449 F ATOM 18627 N SERF 76 47629 18154 33742 1005494 F ATOM 18712 C VALF 86 46844 18995-39141 1004657 F

ATOM 18628 CA SERF 76 47637 19041 -34896 1005602 F ATOM 18713 O VALF 86 47770 19077-38344 1005126 F

ATOM 18629 CB SERF 76 46407 19946-34889 1007968 F ATOM 18714 N ASNF 87 46080 17916-39229 1005846 F

ATOM 18630 OG SERF 76 45215 19196-34857 1008897 F ATOM 18715 CA ASNF 87 46332 16754-38394 1005514 F

ATOM 18631 C SERF 76 48855 19932-34922 1005202 F ATOM 18716 CB ASNF 87 45138 15818-38458 1005892 F

ATOM 18632 O SERF 76 4945620217-33893 1004817 F ATOM 18717 CG ASNF 87 43904 16427-37850 1005922 F

ATOM 18633 N ARGF 77 4921020368-36121 1004504 F ATOM 18718 ODl ASNF 87 43964 17493 -37240 1006183 F

ATOM 18634 CA ARGF 77 50307 21286-36295 1005022 F ATOM 18719 ND2 ASN F 87 42771 15746-38000 1005618 F

ATOM 18635 CB ARGF 77 5139720705-37200 1003950 F ATOM 18720 C ASNF 87 47590 15968-38734 1005396 F ATOM 18636 CG ARGF 77 52278 21807-37846 1004168 F ATOM 18721 O ASNF 87 47824 15627-39893 1005254 F

ATOM 18637 CD ARGF 77 53661 21324-38244 1004255 F ATOM 18722 N LEUF 88 48392 15667-37717 1005027 F

ATOM 18638 NE ARGF 77 5383821178-39683 1004499 F ATOM 18723 CA LEUF 88 49610 14897-37923 1004926 F

ATOM 18639 CZ ARG F 77 5480021781 -40376 1004842 F ATOM 18724 CB LEU F 88 50759 15450-37089 1003057 F

ATOM 18640 NHl ARGF 77 5489621590-41684 1004851 F ATOM 18725 CG LEUF 88 51181 16882-37362 1002750 F

ATOM 18641 NH2 ARG F 77 5565722586-39768 1004828 F ATOM 18726 CDl LEUF 88 52353 17217-36448 1002827 F

ATOM 18642 C ARGF 77 49731 22517-36968 1004856 F ATOM 18727 CD2 LEU F 88 51537 17049-38820 1002607 F

ATOM 18643 O ARGF 77 48943 22410-37912 1005431 F ATOM 18728 C LEUF 88 49363 13468-37502 1004850 F

ATOM 18644 N ILEF 78 50082 23683-36455 1004134 F ATOM 18729 O LEUF 88 49763 12533-38178 1004697 F

ATOM 18645 CA ILEF 78 49658 24914-37092 1004003 F ATOM 18730 N LEUF 89 48713 13313-36360 1004013 F

ATOM 18646 CB ILEF 78 48699 25792-36166 1006156 F ATOM 18731 CA LEUF 89 48411 11999-35811 1003905 F ATOM 18647 CG2 ILEF 78 4821024990-34984 1006206 F ATOM 18732 CB LEU F 89 49371 11678 -34675 1004057 F

ATOM 18648 CGl ILEF 78 4938727058-35697 1006323 F ATOM 18733 CG LEUF 89 50851 11806-34980 1004455 F

ATOM 18649 CDl ILEF 78 4956028086-36790 1006355 F ATOM 18734 CDl LEUF 89 51600 11933-33675 1004428 F

ATOM 18650 C ILEF 78 5103025540-37398 1004220 F ATOM 18735 CD2 LEU F 89 51324 10612-35762 1004367 F

ATOM 18651 O ILEF 78 51719 26074-36532 1004075 F ATOM 18736 C LEUF 89 46988 12037 -35272 1004072 F

ATOM 18652 N ALAF 79 5144625405-38645 1004954 F ATOM 18737 O LEUF 89 46573 13023-34662 1004144 F

ATOM 18653 CA ALAF 79 5274225900-39079 1004614 F ATOM 18738 N SERF 90 46243 10965 35494 1004281 F

ATOM 18654 CB ALAF 79 53095 25276-40409 1005807 F ATOM 18739 CA SERF 90 44864 10914-35044 1004215 F

ATOM 18655 C ALAF 79 52858 27410-39182 1004734 F ATOM 18740 CB SERF 90 43983 11721 -35992 1006796 F

ATOM 18656 O ALAF 79 51883 28105-39446 1004754 F ATOM 18741 OG SERF 90 42627 11631 -35604 1007218 F

ATOM 18657 N VALF 80 5406927912-38989 1005287 F ATOM 18742 C SER F 90 44320 9495 -34948 1004078 F ATOM 18658 CA VALF 80 5431229344-39073 1005536 F ATOM 18743 O SERF 90 44664 8618-35748 1004060 F

ATOM 18659 CB VALF 80 5576429703-38707 1005763 F ATOM 18744 N ALA F 91 43469 9261 -33960 1004648 F

ATOM 18660 CGl VALF 80 55985 31 196-38865 1005603 F ATOM 18745 CA ALAF 91 42879 7940 -33802 1004457 F

ATOM 18661 CG2 VALF 80 56059 29277-37289 1005933 F ATOM 18746 CB ALAF 91 43720 7085 -32854 1003945 F

ATOM 18662 C VALF 80 54058 29813-40492 1005991 F ATOM 18747 C ALAF 91 41457 8086 -33286 1004854 F

ATOM 18663 O VALF 80 53621 30938-40709 1005850 F ATOM 18748 O ALAF 91 41099 9118-32719 1005041 F

ATOM 18664 N SERF 81 54332 28945-41459 1006948 F ATOM 18749 N ILEF 92 40647 7055 -33499 1006629 F

ATOM 18665 CA SERF 81 5412729297-42856 1007234 F ATOM 18750 CA ILEF 92 39255 7064 -33066 I 006627 F

ATOM 18666 CB SERF 81 5522028675-43709 1004456 F ATOM 18751 CB ILEF 92 38309 7154-34267 1005903 F

ATOM 18667 OG SERF 81 56481 29195-43342 1004760 F ATOM 18752 CG2 ILE F 92 36883 7279-33792 1006510 F

ATOM 18668 C SERF 81 5276028904^13414 1007652 F ATOM 18753 CGl ILEF 92 38681 8364-35127 1005714 F

ATOM 18669 O SERF 81 52541 29006-44618 1007704 F ATOM 18754 CDl ILEF 92 37921 8448-36433 1006301 F

ATOM 18670 N TYRF 82 51851 28458-42547 1005140 F ATOM 18755 C ILEF 92 38976 5772-32330 1006610 F

ATOM 18671 CA TYRF 82 5051228069^2965 1005344 F ATOM 18756 O ILEF 92 39555 4743-32661 1006718 F

ATOM 18672 CB TYRF 82 5056526755-43758 1003726 F ATOM 18757 N LYSF 93 38100 5821-31332 1008359 F

ATOM 18673 CG TYRF 82 49261 26393-44447 1004046 F ATOM 18758 CA LYSF 93 37773 4624 -30569 1008424 F

ATOM 18674 CDlTYRF 82 48589 25201 -44150 1004275 F ATOM 18759 CB LYSF 93 38672 4539-29331 1006033 F

ATOM 18675 CElTYRF 82 4735524900^)4732 1004454 F ATOM 18760 CG LYSF 93 38977 3120 28889 1006402 F

ATOM 18676 CD2TYRF 82 4866627266-45351 1004255 F ATOM 18761 CD LYSF 93 40281 3055-28099 1006379 F

ATOM 18677 CE2TYRF 82 4743526975 -45935 1004402 F ATOM 18762 CE LYSF 93 40659 1609 -27766 1006369 F

ATOM 18678 CZ TYRF 82 4678825799-45621 1004471 F ATOM 18763 NZ LYSF 93 41959 1482 27028 1006626 F

ATOM 18679 OH TYRF 82 4556725551 -46196 1004313 F ATOM 18764 C LYSF 93 36303 4657-30169 1008594 F

ATOM 18680 C TYRF 82 49628 27914-41730 1005287 F ATOM 18765 O LYSF 93 35804 5697 -29740 1008386 F

ATOM 18681 O TYRF 82 49309 26791-41324 1005305 F ATOM 18766 N SERF 94 35616 3525-30326 1008946 F

ATOM 18682 N GLNF 83 49237 29051-41146 1005856 F ATOM 18767 CA SERF 94 34191 3409-29996 1009191 F

ATOM 18683 CA GLNF 83 48405 29097-39941 1005845 F ATOM 18768 CB SERF 94 33430 2753-31151 10011258 F

ATOM 18684 CB GLNF 83 4808530540-39569 1006337 F ATOM 18769 OG SERF 94 33949 1464-31441 10011501 F

ATOM 18685 CG GLNF 83 4896031155-38491 1006764 F ATOM 18770 C SERF 94 34007 2573 -28737 1009450 F

ATOM 18686 CD GLNF 83 50322 31547-39001 1006868 F ATOM 18771 O SERF 94 33975 1347-28794 1009577 F

ATOM 18687 OElGLNF 83 51055 32280-38342 1006770 F ATOM 18772 N PROF 95 33857 3231 -27583 1009151 F

ATOM 18688 NE2 GLN F 83 5067231061-40184 1006618 F ATOM 18773 CD PROF 95 33626 4682 -27443 1008669 F

ATOM 18689 C GLNF 83 47083 28358-39985 1005663 F ATOM 18774 CA PROF 95 33682 2548 -26299 1009545 F

ATOM 18690 O GLNF 83 46041 28998-40027 1005408 F ATOM 18775 CB PROF 95 33703 3698 -25300 1008963 F

ATOM 18691 N THRF 84 47102 27030-39959 1006496 F ATOM 18776 CG PROF 95 33011 4791-26064 1008708 F ATOM 18692 CA THRF 84 4585926264-39968 1005733 F ATOM 18777 C PROF 95 32392 1746 -26233 1009988 F

ATOM 18693 CB THRF 84 45321 26018-41379 1007284 F ATOM 18778 O PROF 95 32398 0520-26343 10010331 F

ATOM 18694 OGl THRF 84 45275 27250-42099 1007339 F ATOM 18779 N CYSF 96 31283 2451 -26049 10016402 F

ATOM 18695 CG2THRF 84 43921 25423-41311 1007559 F ATOM 18780 CA CYSF 96 29987 1809-25968 10016381 F

ATOM 18696 C THRF 84 46130 24907-39373 1005384 F ATOM 18781 C CYSF 96 29480 1481-27355 10016491 F

ATOM 18697 O THRF 84 47148 24284-39674 1005515 F ATOM 18782 O CYSF 96 29100 2368-28117 10016521 F

ATOM 18698 N LYSF 85 45221 24442-38530 1004322 F ATOM 18783 CB CYSF 96 28995 2715-25244 10020084 F

ATOM 18699 CA LYSF 85 4539023144-37937 1004308 F ATOM 18784 SG CYSF 96 29357 2893 -23470 10020084 F

ATOM 18700 CB LYSF 85 44248 22842-36969 1007090 F ATOM 18785 N GLNF 97 29495 0194-27676 10020078 F

ATOM 18701 CG LYSF 85 44493 23218-35522 I 006784 F ATOM 18786 CA GLNF 97 29033 -0289 -28967 10020078 F

ATOM 18702 CD LYSF 85 4336822647-34665 1006624 F ATOM 18787 CB GLNF 97 29584 -1696-29212 10015903 F ATOM 18703 CE LYSF 85 43607 22857-33179 1006454 F ATOM 18788 CG GLNF 97 31091 -1806-29037 10015903 F

ATOM 18704 NZ LYSF 85 43695 24300-32797 1006279 F ATOM 18789 CD GLNF 97 31558 -3241 -28870 10015903 F

ATOM 18705 C LYSF 85 4538422090-39039 1004288 F ATOM 18790 OEl GLNF 97 31333 -4086 -29736 10015903 F

ATOM 18706 O LYSF 85 44462 22037 39851 1004333 F ATOM 18791 NE2 GLN F 97 32214 -3522-27750 10015903 F

ATOM 18707 N VALF 86 46439 21282-39099 1004301 F ATOM 18792 C GLNF 97 27505 -0317 -28956 10020078 F

ATOM 18708 CA VALF 86 4649220175-40041 1004590 F ATOM 18793 O GLNF 97 26891 -1283 -29408 10020078 F

ATOM 18709 CB VALF 86 4755720366-41170 1004322 F ATOM 18794 N ARGF 98 26906 0749 -28426 10020084 F

ATOM 18710 CGlVALF 86 4719721555-42020 1004996 F ATOM 18795 CA ARGF 98 25451 0882 28333 10020084 F 65251/C766

ATOM 18796 CB ARG F 98 24808 0573 -29695 10020084 F ATOM 18881 CE2TRPF109 32825 4646-21456 1007671 F ATOM 18797 CG ARG F 98 23285 0513-29693 10020084 F ATOM 18882 CE3 TRP F 109 35153 4043-21755 1007756 F ATOM 18798 CD ARG F 98 22647 1847 -29332 10020084 F ATOM 18883 CDl TRP F 109 32000 2833 -20450 1007555 F ATOM 18799 NE ARG F 98 21206 1718-29131 10020084 F ATOM 18884 NEl TRP F 109 31693 4085-20931 1007387 F ATOM 18800 CZ ARG F 98 20360 1231 -30034 10020084 F ATOM 18885 CZ2TRPF109 33017 5894 -22055 1007316 F ATOM 18801 NHl ARG F 98 19067 1153-29754 10020084 F ATOM 18886 CZ3TRPF109 35346 5287 -22353 1007732 F ATOM 18802 NH2 ARG F 98 20802 0823-31217 10020084 F ATOM 18887 CH2TRPF109 34281 6196 -22497 1007296 F ATOM 18803 C ARG F 98 24848 0012 27239 10020084 F ATOM 18888 C TRP F 109 35981 2289-19125 1 009483 F ATOM 18804 O ARG F 98 23630 -0039 -27047 10020084 F ATOM 18889 O TRP F 109 35871 3497-18911 1 009644 F ATOM 18805 N GLUF 99 25707 -0729-26515 10019651 F ATOM 18890 N TYRFIlO 37115 I 710-19499 1 008153 F ATOM 18806 CA GLU F 99 25264 -1619 -25440 10019651 F ATOM 18891 CA TYR F 110 38338 2468-19711 1008017 F ATOM 18807 CB GLU F 99 26439 -1993 -24525 10019087 F ATOM 18892 CB TYR F 110 39422 2026 18733 1008733 F ATOM 18808 CG GLU F 99 27736 -1242 -24805 10019087 F ATOM 18893 CG TYR F 110 39100 2282-17281 1009088 F ATOM 18809 CD GLU F 99 28568 -1891 -25897 10019087 F ATOM 18894 CDl TYRF 110 38143 1519-16609 1009497 F ATOM 18810 OEl GLU F 99 27988 -2286-26929 10019087 F ATOM 18895 CEl TYR F 110 37873 1734 15254 1009529 F ATOM 18811 OE2 GLU F 99 29802 1998-25725 10019087 F ATOM 18896 CD2TYRF110 39776 i 3272-16567 1009111 F ATOM 18812 C GLU F 99 24154 -0997-24597 10019651 F ATOM 18897 CE2TYRF110 39515 3496-15219 1009648 F ATOM 18813 O GLUF 99 23119 -1621-24376 10019651 F ATOM 18898 CZ TYRFIlO 38568 2727-14567 1009677 F ATOM 18814 N THRFlOO 24382 0231-24135 10019808 F ATOM 18899 OH TYR F 110 38338 2947 -13230 1009797 F ATOM 18815 CA THRFlOO 23421 0963-23311 10019808 F ATOM 18900 C TYRFIlO 38824 2241-21137 1 007868 F ATOM 18816 CB THRFlOO 22234 1491 -24157 10015469 F ATOM 18901 O TYRFIlO 38800 1118-21637 1 007987 F ATOM 18817 OGl THRFlOO 21614 0404-24854 10015497 F ATOM 18902 N GLUFlIl 39270 3312-21782 1 I 007412 F ATOM 18818 CG2THRF100 22712 2525-25166 10015586 F ATOM 18903 CA GLUFlIl 39751 3235-23153 1007214 F ATOM 18819 C THRFlOO 22873 0116-22163 10019808 F ATOM 18904 CB GLU Fill 38612 3564-24116 1007825 F ATOM 18820 O THRFlOO 22186 -0880-22383 10019808 F ATOM 18905 CG GLU Fill 38585 2682 -25327 1008517 F ATOM 18821 N PROFlOl 23170 0511-20914 10020084 F ATOM 18906 CD GLU Fill 38390 1228 -24965 1009014 F ATOM 18822 CD PROF 101 23904 1732 20537 10011731 F ATOM 18907 OEl GLU Fill 37352 0920-24343 1009035 F ATOM 18823 CA PRO F 101 22715 0204-19719 10020084 F ATOM 18908 OE2 GLU Fill 39269 0399-25300 1009730 F ATOM 18824 CB PROFlOl 22947 0816-18609 10011826 F ATOM 18909 C GLUFlIl 40905 4211-23376 1 007272 F ATOM 18825 CG PRO F 101 24193 1501 -19067 10011629 F ATOM 18910 O GLUFlIl 40700 5426-23405 1 1007808 F ATOM 18826 C PROFlOl 21260 -0668 -19799 10020084 F ATOM 18911 N PRO F 112 42139 3692-23518 1 006772 F ATOM 18827 O PROFlOl 20334 0144-19788 10020084 F ATOM 18912 CD PROF 112 42556 2321 -23173 1005144 F ATOM 18828 N GLUF 102 21076 -1983-19880 10019164 F ATOM 18913 CA PROF 112 43318 4535 -23740 1006695 F ATOM 18829 CA GLU F 102 19753 -2593-19962 10019164 F ATOM 18914 CB PROF 112 44411 3775 23005 1004751 F ATOM 18830 CB GLU F 102 19881 -4109-19750 10015458 F ATOM 18915 CG PRO F 112 44077 2374 -23358 1004864 F ATOM 18831 CG GLU F 102 18567 -4882-19724 10015578 F ATOM 18916 C PRO F 112 43639 4676 -25227 1006398 F ATOM 18832 CD GLU F 102 17781 -4668-18442 10015709 F ATOM 18917 O PRO F 112 43263 3826 -26032 1 006411 F ATOM 18833 OEl GLU F 102 18316 -4973-17353 10015790 F ATOM 18918 N ILEF 113 44324 ! i 757 -25582 1 006067 F ATOM 18834 OE2GLUF102 16628 -4193-18526 10015621 F ATOM 18919 CA ILEF 113 44727 5984-26964 1 006264 F ATOM 18835 C GLU F 102 18780 -1993-18946 0018820 F ATOM 18920 CB ILE F 113 43793 6949-27699 1 005330 F ATOM 18836 O GLU F 102 17606 -1780-19250 0018526 F ATOM 18921 CG2ILEF113 44303 7142-29116 1004932 F ATOM 18837 N GLY F 103 19275 -1718-17743 0014571 F ATOM 18922 CGl ILEF 113 42370 6402 -27743 1005036 F ATOM 18838 CA GLYF 103 18435 -1150-16704 10014303 F ATOM 18923 CDl ILEF 113 41416 7254 -28586 1005084 F ATOM 18839 C GLY F 103 18888 -1584-15323 10014090 F ATOM 18924 C ILE F 113 46121 6599-26999 Ii OO 6686 F ATOM 18840 O GLY F 103 18440 -1045-14311 10013539 F ATOM 18925 O ILEF 113 46376 ' '618-26352 1 007026 F ATOM 18841 N ALA F 104 19784 -2565 15286 10017434 F ATOM 18926 N TYR F 114 47022 5981 -27753 1 004112 F ATOM 18842 CA ALA F 104 20319 -3083-14033 10017434 F ATOM 18927 CA TYRF 114 48380 6504 -27870 1003940 F ATOM 18843 CB ALA F 104 19629 -4400-13677 1008802 F ATOM 18928 CB TYRF 114 49409 5430 -27526 1004356 F ATOM 18844 C ALA F 104 21829 3291-14156 10017434 F ATOM 18929 CG TYRF 114 50812 5962 -27411 1004142 F ATOM 18845 O ALA F 104 22280 -4116-14952 10017434 F ATOM 18930 CDl TYR F 114 51259 6540-26231 1004571 F ATOM 18846 N GLU F 105 22591 -2527-13369 10017066 F ATOM 18931 CEl TYR F 114 52547 7052-26126 1004528 F ATOM 18847 CA GLU F 105 24059 2575-13332 10017066 F ATOM 18932 CD2TYRF114 51689 5907 -28498 1004159 F ATOM 18848 CB GLU F 105 24584 -3939 -13804 1002OO 84 F ATOM 18933 CE2 TYR F 114 52978 6420-28414 1004592 F ATOM 18849 CG GLU F 105 24255 -5095-12875 10020084 F ATOM 18934 CZ TYR F 114 53406 6992 -27223 1004600 F ATOM 18850 CD GLU F 105 24844 -4914-11489 10020084 F ATOM 18935 OH TYRF 114 54688 7513-27123 1004550 F ATOM 18851 OEl GLU F 105 24442 -3960-10789 10020084 F ATOM 18936 C TYR F 114 48628 7005 29294 1 003924 F ATOM 18852 OE2GLUF105 25712 -5723 -11101 10020084 F ATOM 18937 O TYR F 114 48153 6427-30267 1 004215 F ATOM 18853 C GLU F 105 24747 -1466-14132 10017066 F ATOM 18938 N LEU F 115 49393 8080-29405 1 003971 F ATOM 18854 O GLU F 105 24543 -0281-13863 10017066 F ATOM 18939 CA LEU F 115 49712 8681-30692 1003875 F ATOM 18855 N ALA F 106 25570 -1870-15101 10017555 F ATOM 18940 CB LEU F 115 48857 9934 -30882 1005580 F ATOM 18856 CA ALA F 106 26328 0963-15970 10017555 F ATOM 18941 CG LEU F 115 47727 9968-31907 1005905 F ATOM 18857 CB ALA F 106 25518 0299-16275 1009012 F ATOM 18942 CDl LEU F 115 47003 8636-31981 1005743 F ATOM 18858 C ALA F 106 27677 -0584-15362 10017555 F ATOM 18943 CD2LEUF115 46789 11097-31528 1006235 F ATOM 18859 O ALA F 106 27821 0482-14764 10017555 F ATOM 18944 C LEUF 115 51185 9072-30695 1 004119 F ATOM 18860 N LYS F 107 28662 -1466-15526 10015121 F ATOM 18945 O LEUF 115 51697 9572-29691 1 004372 F ATOM 18861 CA LYS F 107 30011 -1245-15005 10014533 F ATOM 18946 N GLY F 116 51867 8853 -31814 1 003912 F ATOM 18862 CB LYS F 107 30852 -2522 -15143 10017449 F ATOM 18947 CA GLY F 116 53268 9222-31875 1003346 F ATOM 18863 CG LYS F 107 30548 3627 14138 10017444 F ATOM 18948 C GLY F 116 53910 9045-33233 1 003731 F ATOM 18864 CD LYS F 107 29149 -4197-14299 10017587 F ATOM 18949 O GLYF 116 53627 8077-33943 1 : 003619 F ATOM 18865 CE LYS F 107 28959 -5426-13419 10017191 F ATOM 18950 N GLY F 117 54786 9983-33590 1 003482 F ATOM 18866 NZ LYS F 107 29277 -5150-11989 10017217 F ATOM 18951 CA GLYF 117 55474 9928 -34868 1003782 F ATOM 18867 C LYS F 107 30720 -0106 -15739 10014081 F ATOM 18952 C GLY F 117 56536 11004 -34965 1003913 F ATOM 18868 O LYS F 107 30244 0370-16772 10013994 F ATOM 18953 O GLY F 117 56597 11895 -34120 1004051 F ATOM 18869 N PRO F 108 31869 0353-15205 10011517 F ATOM 18954 N VALF 118 57374 10925-35994 1003251 F ATOM 18870 CD PRO F 108 32443 0021-13885 1006786 F ATOM 18955 CA VALF 118 58442 11901 -36201 1003529 F ATOM 18871 CA PRO F 108 32628 1439-15836 10011391 F ATOM 18956 CB VALF 118 59756 11189-36570 1003383 F ATOM 18872 CB PRO F 108 33431 2013-14672 1006701 F ATOM 18957 CGl VAL F 118 60853 12192-36845 1003523 F ATOM 18873 CG PRO F 108 33762 0792-13887 1006439 F ATOM 18958 CG2VALF118 60158 i 10284-35427 ¹ 1003389 F ATOM 18874 C PRO F 108 33530 0892-16943 10011314 F ATOM 18959 C VALF 118 58048 12886-37298 1003320 F ATOM 18875 O PRO F 108 33851 -0298-16960 10011132 F ATOM 18960 O VALF 118 57517 12491-38335 1003715 F ATOM 18876 N TRP F 109 33926 1760-17870 1009577 F ATOM 18961 N PHEF 119 58312 1 14171 -37057 1 1004329 F ATOM 18877 CA TRP F 109 34797 1353-18967 1009322 F ATOM 18962 CA PHE F 119 57952 15224-38000 1004460 F ATOM 18878 CB TRP F 109 34033 1297-20291 1007876 F ATOM 18963 CB PHE F 119 56607 15844-37590 1003077 F ATOM 18879 CG TRP F 109 33317 2557-20652 1007845 F ATOM 18964 CG PHE F 119 55459 14883-37609 1002837 F ATOM CD2 TRP F 109 33873 3709-21296 1007746 F ATOM 18965 CDl PHEF 119 55214 14060 -36526 1002656 F 65251/C766

ATOM 18966 CD2 PHE F 119 54648 14769-38728 1002705 F ATOM 19051 CB GLU F 130 42476 18734-29190 1008132 F ATOM 18967 CEl PHE F 119 54173 13123-36553 1002763 F ATOM 19052 CG GLU F 130 43193 20070 -29063 1008086 F

ATOM 18968 CE2 PHE F 119 53600 13832-38765 1002786 F ATOM 19053 CD GLU F 130 42928 21011-30229 1008635 F

ATOM 18969 CZ PHEF 119 53365 13010-37678 1002695 F ATOM 19054 OEl GLU F 130 43413 22166-30192 1008772 F

ATOM 18970 C PHEF119 58967 16358-38160 1004551 F ATOM 19055 OE2 GLU F 130 4224420596-31186 1008616 F

ATOM 18971 O PHE F 119 59680 16704-37227 1004161 F ATOM 19056 C GLU F 130 42263 16375-28389 1004682 F

ATOM 18972 N GLN F 120 59010 16932-39360 1003685 F ATOM 19057 O GLU F 130 42608 15381 -29020 1004674 F

ATOM 18973 CA GLN F 120 59877 18068-39683 1004022 F ATOM 19058 N ILEF 131 41 143 16421 -27679 1005924 F

ATOM 18974 CB GLN F 120 60098 18144-41195 1006606 F ATOM 19059 CA ILE F 131 40196 15311-27643 1006178 F

ATOM 18975 CG GLN F 120 61535 18069-41654 1006621 F ATOM 19060 CB ILE F 131 40203 14580-26300 1006237 F ATOM 18976 CD GLN F 120 62420 19098-40989 1006581 F ATOM 19061 CG2 ILEF 131 41533 13880-26096 1006260 F

ATOM 18977 OEl GLN F 120 62025 20243-40808 1006537 F ATOM 19062 CGl ILEF 131 39899 15572-25182 1005856 F

ATOM 18978 NE2 GLN F 120 63634 18695-40632 1006864 F ATOM 19063 CDl ILEF 131 39806 14927-23810 1005717 F

ATOM 18979 C GLN F 120 59079 19304-39235 1003936 F ATOM 19064 C ILEF 131 38816 15917-27849 1006367 F

ATOM 189800 GLN F 120 57953 19516-39695 1004206 F ATOM 19065 O ILE F 131 38637 17116-27671 1006439 F

ATOM 18981 N LEU F 121 5964820111 -38343 1003202 F ATOM 19066 N ASN F 132 37843 15094-28217 1006790 F

ATOM 18982 CA LEU F 121 5896921305-37834 1003368 F ATOM 19067 CA ASN F 132 36495 15585-28464 1006490 F

ATOM 1S983 CB LEUF121 58671 21133-36343 1002855 F ATOM 19068 CB ASNF 132 35896 14829 -29643 1007152 F

ATOM 18984 CG LEU F 121 5732420542-35927 1002682 F ATOM 19069 CG ASN F 132 35683 13364-29333 1007022 F

ATOM 18985 CD1 LEUF121 56804 19581-36969 1002821 F ATOM 19070 ODl ASN F 132 36529 12721 -28715 1007191 F

ATOM 18986 CD2 LEU F 121 57485 19870-34559 1002231 F ATOM 19071 ND2 ASN F 132 34553 12824 -29768 1006805 F ATOM 18987 C LEU F 121 5977522580-38035 1003572 F ATOM 19072 C ASN F 132 35559 15477-27256 1006255 F

ATOM 18988 O LEU F 121 6099922549-38047 1004099 F ATOM 19073 O ASN F 132 34622 16265-27133 1006572 F

ATOM 18989 N GLUF122 5906923699-38186 1005002 F ATOM 19074 N ARG F 133 35804 14512-26368 1006081 F

ATOM 18990 CA GLU F 122 59691 25014-38377 1005156 F ATOM 19075 CA ARG F 133 34958 14326-25188 1005640 F

ATOM 18991 CB GLU F 122 58860 25906-39309 1008761 F ATOM 19076 CB ARG F 133 34298 12944-25222 1009985 F

ATOM 18992 CG GLU F 122 58622 25438-40725 1009065 F ATOM 19077 CG ARG F 133 33383 12719-26410 10010243 F

ATOM 18993 CD GLU F 122 5766726369-41474 1009593 F ATOM 19078 CD ARG F 133 32288 13773-26466 10010767 F

ATOM 18994 OEl GLU F 122 5649726503-41051 1009743 F ATOM 19079 NE ARG F 133 31448 13766-25270 10010553 F

ATOM 18995 OE2 GLU F 122 58089 26975-42481 1009602 F ATOM 19080 CZ ARG F 133 30575 12808-24966 10010663

ATOM 18996 C GLU F 122 59745 25740-37040 1005036 F ATOM 19081 NHl ARG F 133 29862 12895-23852 10010931

ATOM 18997 O GLU F 122 58913 25507-36164 1005155 F F ATOM 18998 N LYS F 123 6070726639-36888 1004842 F ATOM 19082 NH2 ARG F 133 30405 11768 -25774 I 0010592

ATOM 18999 CA LYS F 123 6078027417-35663 1004927 F F

ATOM 19000 CB LYS F 123 6196428378-35705 1006886 F ATOM 19083 C ARG F 133 35707 14486-23864 1006099 F

ATOM 19001 CG LYS F 123 6196429361 -34560 1006502 F ATOM 19084 O ARG F 133 35885 13519-23122 1006335 F

ATOM 19002 CD LYS F 123 63096 30356-34691 1006269 F ATOM 19085 N PROF134 36136 15714-23542 1006218 F

ATOM 19003 CE LYS F 123 63057 31386 -33567 1006442 F ATOM 19086 CD PRO F 134 35863 16967-24261 1006935 F

ATOM 19004 NZ LYS F 123 6411832422-33748 1006843 F ATOM 19087 CA PRO F 134 36865 15987-22301 1006590 F

ATOM 19005 C LYS F 123 59475 28212-35592 1005009 F ATOM 19088 CB PRO F 134 37152 17481 -22391 1007207 F

ATOM 19006 O LYS F 123 59103 28893-36549 1005485 F ATOM 19089 CG PRO F 134 35993 17990-23154 1007407 F

ATOM 19007 N GLY F 124 58769 28105-34473 1004901 F ATOM 19090 C PRO F 134 36074 15622-21050 1007108 F

ATOM 19008 CA GLY F 124 5752428828 34327 1005012 F ATOM 19091 O PRO F 134 36615 15589-19949 1007412 F

ATOM 19009 C GLY F 124 5626627997-34467 1005153 F ATOM 19092 N ASPF135 34789 15347-21213 1008541 F

ATOM 19010 O GLY F 124 5518228482-34146 1005233 F ATOM 19093 CA ASP F 135 33973 14977-20071 1008187 F

ATOM 19011 N ASP F 125 56384 26759-34943 1004633 F ATOM 19094 CB ASP F 135 32495 15191-20401 1009880 F

ATOM 19012 CA ASP F 125 5520425907-35105 1004512 F ATOM 19095 CG ASP F 135 32136 14730 21797 1009827 F

ATOM 19013 CB ASP F 125 55583 24567-35751 1006643 F ATOM 19096 ODl ASP F 135 32043 13502-22015 1009421 F

ATOM 19014 CG ASP F 125 5596224701 -37217 1007189 F ATOM 19097 OD2 ASP F 135 31955 15599-22681 1009985 F

ATOM 19015 ODl ASP F 125 55733 25779-37806 1007354 F ATOM 19098 C ASP F 135 34239 13531 19645 1008058 F

ATOM 19016 OD2 ASF F 125 56479 23720-37784 1007055 F ATOM 19099 0 ASP F 135 33833 13115-18566 1008727 F

ATOM 19017 C ASP F 125 5449025643-33774 1004417 F ATOM 19100 N TYR F 136 34937 12773-20486 1007386 F

ATOM 19018 O ASP F 125 5512325574-32722 1004108 F ATOM 19101 CA TYRF 136 35260 11378-20186 1007507 F

ATOM 19019 N ARG F 126 53171 25495-33836 1005233 F ATOM 19102 CB TYR F 136 34970 10491 -21396 1009363 F

ATOM 19020 CA ARG F 126 5235925241-32655 1004781 F ATOM 19103 CG TYRF136 33513 10207-21656 1009324 F

ATOM 19021 CB ARG F 126 51221 26261 -32568 1009709 F ATOM 19104 CDl TYR F 136 32919 10573-22864 1009284 F

ATOM 19022 CG ARG F 126 5164027684-32263 1009558 F ATOM 19105 CEl TYRF 136 31590 10257-23141 1009539 F

ATOM 19023 CD ARG F 126 5045628639-32420 10010050 F ATOM 19106 CD2 TYR F 136 32741 9522-20722 1009541 F

ATOM 19024 NE ARG F 126 5071429931-31786 10010405 F ATOM 19107 CE2 TYR F 136 31411 9201 -20988 1009488 F

ATOM 19025 CZ ARG F 126 50632 30160-30473 10010728 F ATOM 19108 CZ TYR F 136 30844 9572-22200 1009618 F

ATOM 19026 NHl ARG F 126 50895 31370-29986 10010695 F ATOM 19109 OH TYR F 136 29537 9253-22478 10010002 F

ATOM 19027 NH2 ARG F 126 50268 29189-29641 10010547 F ATOM 19110 C TYRF136 36738 11228-19822 1007698 F

ATOM 19028 C ARG F 126 5175723845-32738 1004865 F ATOM 19111 O TYRF136 37239 10117-19632 1007986 F

ATOM 19029 O ARG F 126 5109323521 -33721 1004587 F ATOM 19112 N LEUF 137 37436 12351 -19731 1006945 F

ATOM 19030 N LEU F 127 51968 23026-31710 1004508 F ATOM 19113 CA LEU F 137 38853 12338-19416 1006616 F

ATOM 19031 CA LEU F 127 5143021671 -31702 1004146 F ATOM 19114 CB LEU F 137 39421 13746-19535 1007507 F ATOM 19032 CB LEU F 127 5253020679-31352 1003589 F ATOM 19115 CG LEU F 137 40533 13973-20551 1007280 F

ATOM 19033 CG LEU F 127 5368720709-32344 1003487 F ATOM 19116 CDl LEUF 137 41 114 15357-20326 1007494 F

ATOM 19034 CDl LEU F 127 54873 19962-31782 1003545 F ATOM 19117 CD2 LEU F 137 41613 12923 20400 1007656 F

ATOM 19035 CD2 LEU F 127 53233 20106-33673 1003553 F ATOM 19118 C LEU F 137 39177 11814-18026 1006553 F

ATOM 19036 C LEU F 127 5030521567-30696 1004121 F ATOM 19119 0 LEUF137 38773 12417-17022 1006438 F

ATOM 19037 O LEU F 127 5042222074-29583 1003741 F ATOM 19120 N LEU F 138 39909 10701 -17954 1006670 F

ATOM 19038 N SERF 128 49221 20898-31078 1004309 F ATOM 19121 CA LEU F 138 40313 10166-16652 1006450 F

ATOM 19039 CA SER F 128 4806420756-30200 1004276 F ATOM 19122 CB LEU F 138 40189 8638-16578 1009283 F

ATOM 19040 CB SER F 128 4684221458-30801 1009489 F ATOM 19123 CG LEU F 138 40880 8063-15322 1008895 F

ATOM 19041 OG SER F 128 4718622703-31382 10010074 F ATOM 19124 CDl LEU F 138 40432 8826-14086 1009052 F

ATOM 19042 C SERF128 47729 19297-30018 1004194 F ATOM 19125 CD2 LEU F 138 40578 6589-15169 1009187 F ATOM 19043 O SERF128 47825 18520-30958 1004322 F ATOM 19126 C LEU F 138 41751 10550-16328 1006785 F

ATOM 19044 N ALA F 129 47334 18930-28807 1005841 F ATOM 19127 O LEU F 138 42700 9896-16762 1006700 F

ATOM 19045 CA ALA F 129 46934 17566-28505 1005938 F ATOM 19128 N PHEF139 41905 11619-15562 1007432 F

ATOM 19046 CB ALA F 129 47879 16962 27484 1004104 F ATOM 19129 CA PHE F 139 43225 12069-15167 1007570 F

ATOM 19047 C ALA F 129 45519 17698-27939 1005815 F ATOM 19130 CB PHE F 139 43472 13497-15670 1007760 F

ATOM 19048 O ALA F 129 45337 17996-26765 1005903 F ATOM 19131 CG PHE F 139 42316 14436-15454 1007675 F

ATOM 19049 N GLU F 130 44515 17488-28779 1004946 F ATOM 19132 CDl PHEF 139 42127 15516-16307 1007628 F

ATOM 19050 CA GLU F 130 43127 17636-28351 1005043 F ATOM 19133 CD2PHEF139 41432 14259 14394 1007936 F 65251/C766

ATOM 19134 CEl PHE F 139 41081 16403-16112 1008092 F ATOM 19219 CDl ILEF 150 64245 15403-26283 1004001 F ATOM 19135 CE2PHEF139 40382 15142 14191 1007690 F ATOM 19220 C ILEF150 62390 16048-29464 1004392 F

ATOM 19136 CZ PHEF139 40206 16217-15053 1008084 F ATOM 19221 O ILE F 150 61995 15430-30459 1004303 F

ATOM 19137 C PHE F 139 43330 11987-13646 1007973 F ATOM 19222 N ALAF151 63379 16934-29517 1004897 F

ATOM 19138 O PHE F 139 43919 12856 12995 1007983 F ATOM 19223 CA ALA F 151 64069 17208-30769 1004771 F

ATOM 19139 N ALA F 140 42756 10917-13094 1007661 F ATOM 19224 CB ALA F 151 64736 18571-30706 1002739 F

ATOM 19140 CA ALA F 140 42750 10688-11654 1007791 F ATOM 19225 C ALA F 151 65108 16125-31040 1004867 F

ATOM 19141 CB ALAF140 41625 9737-11289 1006620 F ATOM 19226 0 ALAF151 65988 15869-30216 1005105 F

ATOM 19142 C ALA F 140 44064 10141-11128 1007830 F ATOM 19227 N LEU F 152 65000 15484-32197 1008095 F

ATOM 19143 O ALA F 140 44581 10618-10120 1008019 F ATOM 19228 CA LEU F 152 65938 14435-32562 1008493 F ATOM 19144 N GLU F 141 44601 9139-11813 1008714 F ATOM 19229 CB LEUF 152 65183 13234-33122 1007273 F

ATOM 19145 CA GLU F 141 45844 8523-11381 1009032 F ATOM 19230 CG LEU F 152 64196 12599-32145 1007398 F

ATOM 19146 CB GLU F 141 46075 7197-12119 10017523 F ATOM 19231 CDI LEU F 152 63476 11453-32815 1007167 F

ATOM 19147 CG GLU F 141 47283 6403-11617 10017523 F ATOM 19232 CD2 LEU F 152 64937 12114-30915 1007318 F

ATOM 19148 CD GLU F 141 48598 6841-12250 10017523 F ATOM 19233 C LEU F 152 66944 14936-33591 1008778 F

ATOM 19149 OEl GLU F 141 49659 6642-11621 10017523 F ATOM 19234 O LEU F 152 68127 15096 -33287 I 009364 F

ATOM 19150 OE2 GLU F 141 48577 7370-13381 10017523 F ATOM 19235 N ILEF 153 49352 27229 -4252 1008049 F

ATOM 19151 C GLU F 141 47069 9414-11522 1009242 F ATOM 19236 CA ILEF153 4929726441 -3028 1008049 F

ATOM 19152 O GLU F 141 47479 10046-10553 1009610 F ATOM 19237 CB ILE F 153 48695 25050 -3273 1007045 F

ATOM 19153 N SERF142 47656 9481 -12713 1007654 F ATOM 19238 CG2 ILE F 153 4721425175 -3561 1006723 F

ATOM 19154 CA SERF 142 48861 10284-12869 1007953 F ATOM 19239 CGl ILEF 153 49419 24365 -4428 1006723 F ATOM 19155 CB SERFI42 49909 9789-11879 1005201 F ATOM 19240 CDl ILEF 153 4887822990 -4740 1006723 F

ATOM 19156 OG SER F 142 50957 10718-11735 1005289 F ATOM 19241 C ILE F 153 50671 26274 -2400 1008049 F

ATOM 19157 C SER F 142 49464 10280-14279 1008085 F ATOM 19242 O ILEF 153 51703 26423 -3066 1008049 F

ATOM 19158 O SER F 142 49310 11243-15047 1008594 F ATOM 19243 N THR F 154 5066725944 -1112 1007249 F

ATOM 19159 N GLYF143 50177 9210-14616 1005944 F ATOM 19244 CA THR F 154 51892 25795 -0351 1007249 F

ATOM 19160 CA GLY F 143 50766 9148-15942 1005691 F ATOM 19245 CB THR F 154 5219427118 0367 1006101 F

ATOM 19161 C GLY F 143 49787 8588-16955 1005498 F ATOM 19246 OGl THR F 154 5321627816 -0351 1007129 F

ATOM 19162 0 GLY F 143 50192 7831 -17832 1005697 F ATOM 19247 CG2 THR F 154 5261226884 1830 1007129 F

ATOM 19163 N GLN F 144 48509 8962-16838 1005515 F ATOM 19248 C THRF 154 5187624669 0677 1007249 F

ATOM 19164 CA GLN F 144 47448 8479-17730 1004968 F ATOM 19249 O THR F 154 5084224380 1277 1007249 F

ATOM 19165 CB GLN F 144 46152 8264-16947 1008792 F ATOM 19250 N LEU F 155 53033 24035 0862 1005654 F ATOM 19166 CG GLN F 144 46324 7501-15653 1008720 F ATOM 19251 CA LEU F 155 5319622975 1859 1005654 F

ATOM 19167 CD GLN F 144 45001 7189-14983 1008717 F ATOM 19252 CB LEU F 155 53261 21591 1211 1006859 F

ATOM 19168 OEl GLN F 144 44146 8064-14824 1009274 F ATOM 19253 CG LEU F 155 53319 20447 2230 1006517 F

ATOM 19169 NE2 GLN F 144 44831 5940-14574 1008571 F ATOM 19254 CDl LEU F 155 5214920557 3192 1006517 F

ATOM 19170 C GLN F 144 47149 9421 -18892 1005148 F ATOM 19255 CD2 LEU F 155 53288 19111 1521 1006517 F

ATOM 19171 O GLN F 144 46568 9018-19896 1005379 F ATOM 19256 C LEU F 155 54502 23273 2598 1005654 F

ATOM 19172 N VALF145 47532 10680-18745 1003631 F ATOM 192570 LEU F 155 5558823273 2002 1005654 F

ATOM 19173 CA VALF145 47292 11666-19781 1003456 F ATOM 19258 N LYS F 156 54393 23552 3894 1006700 F

ATOM 19174 CB VAL F 145 46059 12545-19442 1003226 F ATOM 19259 CA LYS F 156 5556823882 4687 1006700 F

ATOM 19175 CGl VAL F 145 45817 13555-20566 1003042 F ATOM 19260 CB LYS F 156 5553425362 5087 1007808 F

ATOM 19176 CG2 VALF 145 44836 11666 19236 1002934 F ATOM 19261 CG LYS F 156 56795 25820 5811 1008027 F

ATOM 19177 C VAL F 145 48517 12556-19914 1003567 F ATOM 19262 CD LYS F 156 56762 27297 6196 1008027 F

ATOM 19178 O VALF 145 48851 13301 -18997 1003835 F ATOM 19263 CE LYS F 156 55761 27581 7315 1008027 F

ATOM 19179 N TYR F 146 49187 12462-21059 1004479 F ATOM 19264 NZ LYS F 156 5584428991 7807 1008027 F

ATOM 19180 CA TYR F 146 50381 13259-21320 1004300 F ATOM 19265 C LYS F 156 5572623034 5938 1006700 F

ATOM 19181 CB TYR F 146 51647 12534-20819 1005468 F ATOM 19266 O LYS F 156 54771 22836 6683 1006700 F

ATOM 19182 CG TYR F 146 51761 11100-21268 1005471 F ATOM 19267 N TYR F 157 5694422534 6148 1006206 F

ATOM 19183 CD1TYRF146 51121 10078-20567 1005410 F ATOM 19268 CA TYRF 157 57301 21725 7316 1006206 F

ATOM 19184 CEl TYR F 146 51180 8754-21007 1005289 F ATOM 19269 CB TYRF 157 5791920387 6886 1007213 F

ATOM 19185 CD2TYRF146 52468 10768-22424 1005030 F ATOM 19270 CG TYRF 157 56924 19366 6385 1005447 F

ATOM 19186 CE2 TYR F 146 52533 9451-22874 1005235 F ATOM 19271 CDl TYR F 157 55581 19699 6196 1005447 F

ATOM 19187 CZ TYRF 146 51888 8447-22162 1005239 F ATOM 19272 CEl TYR F 157 54658 18761 5711 1005447 F

ATOM 19188 OH TYR F 146 51951 7144-22599 1005337 F ATOM 19273 CD2TYRF157 57328 18069 6084 1005447 F

ATOM 19189 C TYRF146 50541 13631 -22800 1004131 F ATOM 19274 CE2 TYR F 157 56418 17120 5604 1005447 F

ATOM 191900 TYR F 146 49889 13073-23693 1003948 F ATOM 19275 CZ TYRF 157 55083 17472 5413 1005447 F

ATOM 19191 N PHE F 147 51439 14578-23030 1004432 F ATOM 19276 OH TYRF 157 54184 16554 4904 1005447 F

ATOM 19192 CA PHE F 147 51709 15110-24343 1004384 F ATOM 19277 C TYRF157 5832022524 8136 1006206 F

ATOM 19193 CB PHE F 147 50713 16242-24593 1003946 F ATOM 19278 O TYRF 157 59335 22990 7603 1006206 F

ATOM 19194 CG PHE F 147 50983 17062-25822 1003851 F ATOM 19279 N ASN F 158 5804422679 9429 1007698 F

ATOM 19195 CDl PHE F 147 51479 16478-26991 1003900 F ATOM 19280 CA ASN F 158 58917 23442 10319 1007698 F

ATOM 19196 CD2 PHE F 147 50667 18427-25831 1004084 F ATOM 19281 CB ASN F 158 58208 24744 10729 1007534 F

ATOM 19197 CEl PHE F 147 51653 17244-28153 1003933 F ATOM 19282 CG ASN F 158 59072 25656 11594 1008604 F

ATOM 19198 CE2 PHE F 147 50836 19199-26986 1003941 F ATOM 19283 ODl ASN F 158 60195 25305 11966 1008604 F

ATOM 19199 CZ PHEF 147 51331 18604-28150 1004025 F ATOM 19284 ND2 ASN F 158 58533 26835 11911 1008604 F ATOM 19200 C PHE F 147 53147 15618-24297 1004538 F ATOM 19285 C ASN F 158 59262 22626 11557 1007698 F

ATOM 19201 O PHE F 147 53527 16345-23384 1004286 F ATOM 192860 ASNF158 58382 22292 12348 1007698 F

ATOM 19202 N GLY F 148 53962 15214-25262 1003559 F ATOM 19287 N TYR F 159 60539 22285 11703 1005988 F

ATOM 19203 CA GLY F 148 55336 15669-25268 1004007 F ATOM 19288 CA TYRF 159 61012 21539 12871 1005988 F

ATOM 19204 C GLY F 148 56002 15629-26625 1004229 F ATOM 19289 CB TYRF 159 6190620350 12487 1006169 F

ATOM 19205 O GLY F 148 55461 15100-27592 1004490 F ATOM 19290 CG TYRF 159 61251 19255 11677 1006525 F

ATOM 19206 N ILE F 149 57185 16221 -26688 1004763 F ATOM 19291 CDl TYRF 159 61120 19370 10293 1006525 F

ATOM 19207 CA ILE F 149 57980 16256-27901 1004604 F ATOM 19292 CEl TYR F 159 60584 18333 9532 1006525 F

ATOM 19208 CB ILEF 149 57615 17446-28810 1005912 F ATOM 19293 CD2TYRF159 60819 18075 12284 1006525 F

ATOM 19209 CG2 ILE F 149 56126 17502 -29026 1005967 F ATOM 19294 CE2TYRF159 60282 17031 11534 1006525 F

ATOM 19210 CGl ILE F 149 58051 18755-28176 1005516 F ATOM 19295 CZ TYR F 159 60170 17162 10159 1006525 F ATOM 19211 CDl ILEF 149 57846 19932-29096 1005841 F ATOM 19296 OH TYR F 159 59675 16113 9413 1006525 F

ATOM 19212 C ILE F 149 59446 16374-27514 1004808 F ATOM 19297 C TYRF 159 61855 22509 13687 1005988 F

ATOM 19213 O ILE F 149 59794 16955-26494 1005325 F ATOM 19298 O TYRF159 62773 23141 13158 1005988 F

ATOM 19214 N ILEF 150 60302 15806 28338 1004207 F ATOM 19299 N THR F 160 6156222622 14977 1008288 F

ATOM 19215 CA ILE F 150 61731 15836-28100 1004258 F ATOM 19300 CA THRF 160 6232423539 15814 1008288 F

ATOM 19216 CB ILEF150 62204 14497-27468 1004401 F ATOM 19301 CB THR F 160 61589 24879 15940 1009468 F

ATOM 19217 CG2ILEF150 61753 13330-28313 1004731 F ATOM 19302 OGl THR F 160 61281 25374 14633 1008202 F

ATOM 19218 CGl ILE F 150 63727 14480-27329 1004200 F ATOM 19303 CG2THRF160 62453 25892 16663 1008202 F 65251/C766

ATOM 19304 C THRF 160 62645 23052 17230 1008288 F ATOM 19389 N VALF 172 59362 21223 18570 1006393 F ATOM 19305 O THR F 160 6174722643 17982 1008288 F ATOM 19390 CA VAL F 172 58044 21 326 17958 1006393 F

ATOM 19306 N VAL F 161 63931 23080 17582 1007287 F ATOM 19391 CB VALF 172 57372 22688 18162 1006639 F

ATOM 19307 CA VAL F 161 6433722711 18936 1007287 F ATOM 19392 CGl VAL F 172 56644 22706 19467 1005840 F

ATOM 19308 CB VALF161 65431 21607 18981 1009402 F ATOM 19393 CG2 VALF172 58408 23798 18074 1005840 F

ATOM 19309 CGl VALF 161 65008 20422 18142 1007853 F ATOM 19394 C VALF 172 58153 21 135 16465 1006393 F

ATOM 19310 CG2 VALF 161 66759 22158 18535 1007853 F ATOM 19395 O VALF 172 59207 21354 15860 1006393 F

ATOM 19311 C VALF161 6488023993 19562 1007287 F ATOM 19396 N PHE F 173 57035 20736 15880 1008937 F

ATOM 19312 O VALF 161 6562624736 18926 1007287 F ATOM 19397 CA PHE F 173 56946 20528 14457 1008937 F

ATOM 19313 N THRF 162 64485 2425620802 10013107 F ATOM 19398 CB PHE F 173 57054 19049 14121 1009681 F ATOM 19314 CA THR F 162 64908 2546621493 10013107 F ATOM 19399 CG PHEF 173 56668 18746 12718 1007863 F

ATOM 19315 CB THRF 162 63701 2638421757 1009974 F ATOM 19400 CDl PHE F 173 57532 19047 11674 1007863 F

ATOM 19316 OG1 THRF162 62765 26270 20678 1007107 F ATOM 19401 CD2PHEF173 55404 18249 12427 1007863 F

ATOM 19317 CG2 THR F 162 6415027829 21864 1007107 F ATOM 19402 CEl PHE F 173 57142 18864 10365 1007863 F

ATOM 19318 C THRF 162 6555225141 22832 10013107 F ATOM 19403 CE2PHEF 173 55002 18064 11 117 1007863 F

ATOM 19319 O THRF 162 65201 24148 23471 10013107 F ATOM 19404 CZ PHE F 173 55871 18373 10083 1007863 F

ATOM 19320 N LEU F 163 6649225978 23258 10010483 F ATOM 19405 C PHEF 173 55597 21038 13981 1008937 F

ATOM 19321 CA LEU F 163 67146 25761 24538 10010483 F ATOM 19406 O PHEF 173 54570 20790 14620 1008937 F

ATOM 19322 CB LEU F 163 6847426505 24599 10014120 F ATOM 19407 N TYR F 174 55598 21754 12863 1007123 F

ATOM 19323 CG LEU F 163 696562559624933 1008929 F ATOM 19408 CA TYR F 174 54355 22264 12303 1007123 F

ATOM 19324 CDl LEU F 163 70891 26450 25172 1008929 F ATOM 19409 CB TYRF 174 54268 23788 12414 100121 19 F ATOM 19325 CD2 LEU F 163 69342 24753 26164 1008929 F ATOM 19410 CG TYRF 174 54151 24308 13822 10010723 F

ATOM 19326 C LEU F 163 662392624925660 10010483 ATOM 19411 CDl TYR F 174 55236 24919 14447 10010723 F

ATOM 19327 O LEU F 163 66523 26034 26842 10010483 F ATOM 19412 CEl TYR F 174 55139 25402 15752 10010723 F

ATOM 19328 N LYS F 164 651392689725282 10017579 F ATOM 19413 CD2TYRF174 52955 24187 14537 10010723 F

ATOM 19329 CA LYS F 164 64192 2741926259 10017579 F ATOM 19414 CE2TYRF174 52844 24666 15846 10010723 F

ATOM 19330 CB LYS F 164 63385 26275 26881 10010507 F ATOM 19415 CZ TYRF 174 53943 25273 16446 10010723 F

ATOM 19331 CG LYSF 164 6197626145 26329 10010482 F ATOM 19416 OH TYR F 174 53851 25757 17733 10010723 F

ATOM 19332 CD LYS F 164 61 15827402 26624 10010482 F ATOM 19417 C TYR F 174 54259 21884 10841 1007123 F

ATOM 19333 CE LYS F 164 59728 2729626109 10010482 F ATOM 19418 O TYRF 174 55247 21973 10107 1007123 F

ATOM 19334 NZ LYS F 164 589072847426514 10010482 F ATOM 19419 N ASP F 175 53061 21454 10442 1007488 F

ATOM 19335 C LYS F 164 64970 28151 27338 10017579 F ATOM 19420 CA ASP F 175 52755 21077 9066 1007488 F ATOM 19336 0 LYS F 164 661182853727119 10017579 F ATOM 19421 CB ASP F 175 52184 19655 9010 10011675 F

ATOM 19337 N ASP F 165 64353 28354 28497 10019041 F ATOM 19422 CG ASP F 175 51964 19162 7584 10010496 F

ATOM 19338 CA ASP F 165 65043 2902229591 10019041 F ATOM 19423 ODl ASP F 175 51 671 19988 6697 10010496 F

ATOM 19339 CB ASP F 165 6409929222 30788 10015884 F ATOM 19424 OD2ASPF175 52065 17942 7348 10010496 F

ATOM 19340 CG ASP F 165 633452795431169 10015884 F ATOM 19425 C ASP F 175 51694 22079 8609 1007488 F

ATOM 19341 ODl ASP F 165 63989 26969 31592 10015884 F ATOM 19426 O ASP F 175 50574 22087 9125 1007488 F

ATOM 19342 OD2 ASP F 165 62100 2794431048 10015884 F ATOM 19427 N HIS F 176 52050 22928 7652 1008468 F

ATOM 19343 C ASPF165 66226 2813929971 10019041 F ATOM 19428 CA HIS F 176 51 122 23931 7145 1008468 F

ATOM 19344 O ASP F 165 66958 27664 29102 10019041 F ATOM 19429 CB HIS F 176 51669 25342 7394 10011368 F

ATOM 19345 N ASP F 166 66423 27900 31257 10012856 F ATOM 19430 CG HIS F 176 51570 25801 8816 1008281 F

ATOM 19346 CA ASPF 166 6753827061 31653 10012856 F ATOM 19431 CD2HISF176 52528 26020 9748 1008281 F

ATOM 19347 CB ASP F 166 68153 27591 32946 10018314 F ATOM 19432 NDl HIS F 176 50372 26133 9411 1008281 F

ATOM 19348 CG ASP F 166 6878628955 32761 10018314 F ATOM 19433 CEl HIS F 176 50596 26540 10648 1008281 F

ATOM 19349 ODl ASP F 166 68060 29904 32394 10018314 F ATOM 19434 NE2HISF176 51896 26481 10876 1008281 F

ATOM 19350 OD2 ASP F 166 70010 2907732973 10018314 F ATOM 19435 C HIS F 176 50834 23805 5653 1008468 F

ATOM 19351 C ASP F 166 67165 25592 31798 10012856 F ATOM 19436 O HIS F 176 51753 23791 4833 1008468 F

ATOM 19352 O ASP F 166 66289 25230 32592 10012856 F ATOM 19437 N TYRF 177 49553 23703 5312 1008503 F

ATOM 19353 N GLY F 167 67821 24752 31001 10013234 F ATOM 19438 CA TYR F 177 49126 23663 3919 1008503 F

ATOM 19354 CA GLY F 167 67565 2333031083 10013234 F ATOM 19439 CB TYR F 177 48016 22643 3705 1009956 F

ATOM 19355 C GLY F 167 6751722493 29821 10013234 F ATOM 19440 CG TYR F 177 47509 22667 2288 1009257 F

ATOM 19356 O GLYF167 68481 22387 29057 10013234 F ATOM 19441 CDl TYR F 177 48320 22253 1237 1009257 F

ATOM 19357 N LEUF168 6635621885 29633 10015815 F ATOM 19442 CEl TYR F 177 47886 22329 -0080 1009257 F

ATOM 19358 CA LEU F 168 6608220995 28523 10015815 F ATOM 19443 CD2TYRF177 46242 23 158 1987 1009257 F

ATOM 19359 CB LEU F 168 64808 2021028842 10013504 F ATOM 19444 CE2 TYR F 177 45797 23241 0672 1009257 F

ATOM 19360 CG LEU F 168 64589 1999630346 10013504 F ATOM 19445 CZ TYRF 177 46624 22824 -0357 1009257 F

ATOM 19361 CDl LEU F 168 63235 1935730594 10013504 F ATOM 19446 OH TYR F 177 46192 22907 -1663 1009257 F

ATOM 19362 CD2LEUF168 65710 19135 30909 10013504 F ATOM 19447 C TYR F 177 48566 25071 3731 1008503 F

ATOM 19363 C LEU F 168 65931 21704 27183 10015815 F ATOM 19448 O TYRF 177 47563 25419 4352 1008503 F

ATOM 19364 O LEU F 168 65919 22933 27102 10015815 F ATOM 19449 N ASN F 178 49193 25881 2880 1009921 F

ATOM 19365 N TYR F 169 65830 20902 26131 1009939 F ATOM 19450 CA ASN F 178 48756 27269 2717 1009921 F

ATOM 19366 CA TYR F 169 65648 21413 24787 1009939 F ATOM 19451 CB ASN F 178 47289 27367 2275 1009773 F

ATOM 19367 CB TYR F 169 6663620761 23825 1009643 F ATOM 19452 CG ASN F 178 47093 27015 0816 1009020 F

ATOM 19368 CG TYRF 169 680682116824032 1009643 F ATOM 19453 ODl ASN F 178 48057 26907 0061 1009020 F

ATOM 19369 CDlTYRF 169 68821 2063825072 1009643 F ATOM 19454 ND2ASNF178 45838 26849 0407 1009020 F ATOM 19370 CEl TYRF 169 70149 21011 25254 1009643 F ATOM 19455 C ASNF 178 48907 27835 4123 1009921 F

ATOM 19371 CD2TYRF169 68672 2208423176 1009643 ATOM 19456 O ASN F 178 49921 27599 4777 1009921 F

ATOM 19372 CE2TYRF169 69993 2246623345 1009643 F ATOM 19457 N ASP F 179 47907 28560 4604 10010168 F

ATOM 19373 CZ TYRF 169 70729 2192724385 1009643 F ATOM 19458 CA ASP F 179 47988 29101 5951 10010168 F

ATOM 19374 OH TYRF 169 72041 22311 24546 1009643 F ATOM 19459 CB ASP F 179 47458 30546 5990 1007450 F

ATOM 19375 C TYRF 169 64235 21055 24360 1009939 F ATOM 19460 CG ASP F 179 46037 30678 5447 1007845 F

ATOM 19376 O TYRF 169 63867 19881 24368 1009939 F ATOM 19461 ODl ASP F 179 45415 29658 5074 1007845 F

ATOM 19377 N ASP F 170 634362205724010 1008273 F ATOM 19462 OD2 ASP F 179 45537 31819 5396 1007845 F

ATOM 19378 CA ASP F 170 620792178423562 1008273 F ATOM 19463 C ASP F 179 47227 28221 6947 10010168 F

ATOM 19379 CB ASP F 170 6114922950 23880 10012509 F ATOM 19464 O ASP F 179 46973 28634 8076 10010168 F

ATOM 19380 CG ASP F 170 6044622779 25205 10012509 F ATOM 19465 N GLN F 180 46887 27002 6531 1008925 F ATOM 19381 ODl ASP F 170 60075 2163225533 10012509 F ATOM 19466 CA GLN F 180 46148 26060 7378 1008925 F

ATOM 19382 OD2ASPF170 60251 2378925911 10012509 F ATOM 19467 CB GLN F 180 45182 25233 6531 1008839 F

ATOM 19383 C ASP F 170 6206621520 22066 1008273 F ATOM 19468 CG GLN F 180 44237 26035 5689 1008002 F

ATOM 19384 O ASP F 170 629462197421339 1008273 F ATOM 19469 CD GLN F 180 43392 26958 6515 1008002 F

ATOM 19385 N GLY F 171 61071 20773 21611 10010423 F ATOM 19470 OEl GLN F 180 43667 28156 6606 1008002 F

ATOM 19386 CA GLYF 171 6098020483 20198 10010423 F ATOM 19471 NE2GLNF180 42357 26405 7141 1008002 F

ATOM 19387 C GLY F 171 59554 20555 19704 10010423 F ATOM 19472 C GLN F 180 47021 25078 8162 1008925 F

ATOM 19388 O GLY F 171 58638 2004420353 10010423 F ATOM 19473 O GLN F 180 47752 24278 7576 1008925 F 65251/C766

ATOM 19474 N LEU F 181 46931 25116 9487 1007933 F ATOM 19559 CA THR F 191 57944 1010027676 10012421 F ATOM 19475 CA LEU F 181 4770024183 10297 1007933 F ATOM 19560 CB THRF 191 56751 10033 26713 10011485 F ATOM 19476 CB LEU F 181 47588 24539 11779 1008202 F ATOM 19561 OGl THR F 191 55537 9926 27463 10011485 F ATOM 19477 CG LEU F 181 48262 23535 12713 1006945 F ATOM 19562 CG2 THR F 191 56876 8835 25802 10011485 F ATOM 19478 CDl LEUF 181 4975623477 12406 1006945 F ATOM 19563 C THR F 191 59224 999626850 10012421 F ATOM 19479 CD2LEUF181 48013 23932 14160 1006945 F ATOM 19564 0 THRF191 59668 8893 26527 10012421 F ATOM 19480 C LEUFlSl 47133 22782 10054 1007933 F ATOM 19565 N ARGF192 59800 1113926495 10011481 F ATOM 19481 O LEUF 181 4591822573 10104 1007933 F ATOM 19566 CA ARG F 192 61028 11179 25703 10011481 F ATOM 19482 N VALF 182 4801021826 9777 1009552 F ATOM 19567 CB ARG F 192 62066 10208 26274 10011810 F ATOM 19483 CA VAL F 182 4757220461 9525 1009552 F ATOM 19568 CG ARG F 192 62561 10604 27645 10011810 F ATOM 19484 CB VAL F 182 48175 19926 8218 10011901 F ATOM 19569 CD ARG F 192 63153 12001 27611 10011810 F ATOM 19485 CGl VALF 182 47750 18485 7997 1009749 F ATOM 19570 NE ARG F 192 63459 1250028949 10011810 F ATOM 19486 CG2 VALF182 4773620796 7061 1009749 F ATOM 19571 CZ ARG F 192 64374 11971 29755 10011810 F ATOM 19487 C VAL F 182 47980 19532 10660 1009552 F ATOM 19572 NHl ARG F 192 65084 10922 29359 10011810 ATOM 19488 O VALF 182 47215 18652 11064 1009552 F F ATOM 19489 N THR F 183 49188 19742 11175 1006320 F ATOM 19573 NH2ARGF192 64576 12487 30960 10011810 ATOM 19490 CA THRF 183 49715 18911 12245 1006320 F F ATOM 19491 CB THR F 183 50483 17694 11682 10010318 F ATOM 19574 C ARGF192 60834 10903 24216 10011481 F ATOM 19492 OGl THRF 183 49576 16833 10986 1008977 F ATOM 19575 O ARGF192 61728 10372 23559 10011481 F ATOM 19493 CG2 THRF 183 51162 16917 12800 1008977 F ATOM 19576 N HIS F 193 59663 11257 23694 10011671 F ATOM 19494 C THR F 183 50683 19653 13144 1006320 F ATOM 19577 CA HIS F 193 59364 11093 22276 10011671 F ATOM 19495 O THRF 183 5150420451 12676 1006320 F ATOM 19578 CB HIS F 193 58928 9650 21968 10013039 F ATOM 19496 N LYS F 184 50572 19392 14441 1008494 F ATOM 19579 CG HIS F 193 57559 9293 22455 10013039 F ATOM 19497 CA LYS F 184 51489 19971 15403 008494 F ATOM 19580 CD2HISF193 56511 10061 22836 10013039 F ATOM 19498 CB LYS F 184 5082020988 16319 009971 F ATOM 19581 NDl HIS F 193 57124 7988 22532 10013039 F ATOM 19499 CG LYS F 184 5181021534 17338 1009155 F ATOM 19582 CEl HIS F 193 55867 796722937 10013039 F ATOM 19500 CD LYS F 184 51171 22471 18338 1009155 F ATOM 19583 NE2 HIS F 193 55471 9212 23128 10013039 F ATOM 19501 CE LYS F 184 52183 22913 19385 1009155 F ATOM 19584 C HISF193 58283 12110 21915 10011671 F ATOM 19502 NZ LYS F 184 5156523761 20443 1009155 F ATOM 19585 0 HIS F 193 57712 12733 22806 10011671 F ATOM 19503 C LYS F 184 52008 18823 16242 1008494 F ATOM 19586 N GLY F 194 58002 12291 20629 1009052 F ATOM 19504 O LYS F 184 51245 17967 16694 1008494 F ATOM 19587 CA GLYF 194 57005 13275 20239 1009052 F ATOM 19505 N ILEF 185 53317 18795 16425 1006530 F ATOM 19588 C GLY F 194 55559 12845 20387 1009052 F ATOM 19506 CA ILE F 185 53944 17755 17220 1006530 F ATOM 19589 0 GLY F 194 55269 11656 20487 1009052 F ATOM 19507 CB ILE F 185 54659 16723 16324 10011519 F ATOM 19590 N ASN F 195 54652 13819 20418 1009273 F ATOM 19508 CG2ILEF185 55539 15809 17167 1008411 F ATOM 19591 CA ASN F 195 53218 13552 20520 1009273 F ATOM 19509 CGl ILE F 185 53620 15903 15558 1008411 F ATOM 19592 CB ASN F 195 52682 13827 21928 10012437 F ATOM 19510 CDl ILEF 185 54221 14976 14519 1008411 F ATOM 19593 CG ASN F 195 53171 1283622951 10012437 F ATOM 19511 C ILEF 185 54955 18410 18157 1006530 F ATOM 19594 ODl ASN F 195 53171 11628 22718 10012437 F ATOM 19512 O ILEF 185 55654 19358 17779 1006530 F ATOM 19595 ND2 ASN F 195 53572 13342 24110 10012437 F ATOM 19513 N SER F 186 55004 17930 19395 1008441 F ATOM 19596 C ASN F 195 52485 14478 19566 1009273 F ATOM 19514 CA SERF 186 55948 1846720362 1008441 F ATOM 195970 ASN F 195 52846 15648 19439 1009273 F ATOM 19515 CB SER F 186 55261 19473 21292 10013214 F ATOM 19598 N VALF196 51460 13967 18896 10011841 F ATOM 19516 OG SERF 186 54020 18982 21755 10012125 F ATOM 19599 CA VALF 196 50693 14810 17994 10011841 F ATOM 19517 C SERF 186 56606 1734221152 1008441 F ATOM 19600 CB VALF 196 49887 13987 16980 10010150 F ATOM 19518 O SER F 186 56036 1625621329 1008441 F ATOM 19601 CGl VAL F 196 49049 14915 16121 10010150 F ATOM 19519 N TYR F 187 57827 17607 21597 1008697 F ATOM 19602 CG2VALF196 50823 13171 16113 10010150 F ATOM 19520 CA TYR F 187 58596 16629 22340 1008697 F ATOM 19603 C VALF196 49719 15589 18860 10011841 F ATOM 19521 CB TYRF 187 6007O 17007 22317 10013473 F ATOM 196040 VALF196 48869 14999 19523 10011841 F ATOM 19522 CG TYRF 187 60946 15963 22943 1008894 F ATOM 19605 N ASN F 197 49851 16910 18868 10010992 F ATOM 19523 CDl TYRF 187 61149 14738 22319 1008894 F ATOM 19606 CA ASN F 197 48969 17750 19672 10010992 F ATOM 19524 CEl TYR F 187 61950 13760 22900 1008894 F ATOM 19607 CB ASNF197 49699 1899620164 10011836 F ATOM 19525 CD2TYRF187 61563 16190 24169 1008894 F ATOM 19608 CG ASN F 197 51046 18685 20747 10011836 F ATOM 19526 CE2TYRF187 62365 1522024761 1008894 F ATOM 19609 ODl ASN F 197 51185 17775 21564 10011836 F ATOM 19527 CZ TYRF 187 62557 14006 24121 1008894 F ATOM 19610 ND2 ASN F 197 52056 19447 20338 10011836 F ATOM 19528 OH TYR F 187 63361 13041 24690 1008894 F ATOM 19611 C ASN F 197 47774 18199 18857 10010992 F ATOM 19529 C TYR F 187 58129 16518 23780 1008697 F ATOM 19612 O ASN F 197 46682 18387 19387 10010992 F ATOM 19530 O TYRF 187 58149 17498 24524 1008697 F ATOM 19613 N PHEF198 47990 18375 17561 10010223 F ATOM 19531 N ASN F 188 57712 15315 24160 10014025 F ATOM 19614 CA PHE F 198 46930 18829 16688 10010223 F ATOM 19532 CA ASN F 188 57239 1503625510 10014025 F ATOM 19615 CB PHE F 198 4707020329 16452 10010115 F ATOM 19533 CB ASN F 188 56253 1387025466 10020084 F ATOM 19616 CG PHEF198 45985 20902 15599 10010115 F ATOM 19534 CG ASN F 188 55680 13545 26820 10011855 F ATOM 19617 CDl PHEF 198 4482421403 16172 10010115 F ATOM 19535 ODl ASN F 188 56416 13349 27786 10011855 F ATOM 19618 CD2 PHEF 198 4610420901 14213 10010115 F ATOM 19536 ND2 ASNF188 54358 13479 26901 10011855 F ATOM 19619 CEl PHE F 198 43795 21892 15381 10010115 F ATOM 19537 C ASN F 188 58437 1467426389 10014025 F ATOM 19620 CE2 PHEF 198 4507821388 13410 10010115 F ATOM 19538 O ASN F 188 59053 13625 26200 10014025 F ATOM 19621 CZ PHE F 198 4392221884 13995 10010115 F ATOM 19539 N HIS F 189 58763 15533 27351 10010272 F ATOM 19622 C PHEF198 46925 18126 15344 10010223 F ATOM 19540 CA HIS F 189 59907 15291 28228 10010272 F ATOM 19623 O PHEF198 47974 17791 14797 10010223 F ATOM 19541 CB HIS F 189 60222 1655729004 10014288 F ATOM 19624 N ARG F 199 45728 17915 14816 10010386 F ATOM 19542 CG HIS F 189 60841 17615 28157 10010342 F ATOM 19625 CA ARG F 199 45564 17292 13517 10010386 F ATOM 19543 CD2HISF189 60311 18713 27569 10010342 F ATOM 19626 CB ARG F 199 45441 15777 13630 1008807 F ATOM 19544 NDl HIS F 189 62158 17561 27755 10010342 F ATOM 19627 CG ARG F 199 45235 15134 12267 1008807 F ATOM 19545 CEl HIS F 189 62413 18581 26954 10010342 F ATOM 19628 CD ARG F 199 46527 15132 11465 1008807 F ATOM 19546 NE2HISF189 61308 19295 26825 10010342 F ATOM 19629 NE ARG F 199 47186 13834 11581 1008807 F ATOM 19547 C HIS F 189 59761 14115 29180 10010272 F ATOM 19630 CZ ARG F 199 48498 13654 11683 1008807 F ATOM 19548 O HIS F 189 60751 1349429574 10010272 F ATOM 19631 NHl ARG F 199 49316 14695 11687 1008807 F ATOM 19549 N GLU F 190 58525 1381229547 10012749 F ATOM 19632 NH2ARGF199 48993 12426 11787 1008807 F ATOM 19550 CA GLUF 190 58254 12704 30443 10012749 F ATOM 19633 C ARG F 199 44296 17838 12894 10010386 F ATOM 19551 CB GLU F 190 56795 12772 30896 10018902 F ATOM 19634 O ARG F 199 43207 17661 13438 10010386 F ATOM 19552 CG GLU F 190 56490 12077 32208 10016344 F ATOM 19635 N ALA F 200 44436 18508 11758 1009558 F ATOM 19553 CD GLU F 190 55052 12291 32642 10016344 F ATOM 19636 CA ALAF200 43281 19064 11073 1009558 F ATOM 19554 OEl GLU F 190 54139 11810 31935 10016344 F ATOM 19637 CB ALA F 200 43718 19741 9786 1007798 F ATOM 19555 OE2GLUF190 54833 12947 33683 10016344 F ATOM 19638 C ALA F 200 42267 17959 10777 1009558 F ATOM 19556 C GLU F 190 58514 11412 29670 10012749 F ATOM 19639 O ALA F 200 42627 16860 10345 1009558 F ATOM 19557 O GLU F 190 59323 10580 30079 10012749 F ATOM 19640 N ASPF201 40998 18261 11021 10012299 F ATOM 19558 N THR F 191 57839 1127728531 10012421 F ATOM 19641 CA ASP F 201 39908 17318 10802 10012299 F 65251/C766

ATOM 19642 CB ASP F 201 38 592 17 957 11 247 1 0012605 F ATOM 19727 C HIS F 210 54322 11810 1769 1006708 F

ATOM 19643 CG ASP F 201 38 403 19 348 10 670 1 00126 05 F ATOM 19728 O HIS F 210 55314 12537 1753 1006708 F

ATOM 19644 ODl ASP F 201 39 170 20260 11 055 1 00126 0.' i F ATOM 19729 N THR F211 5346211790 2781 1007483 F

ATOM 19645 OD2 ASP F 201 37498 19 528 9 825 i 1 00126 05 F ATOM 19730 CA THR F 211 53708 12586 3973 1007483 F

ATOM 19646 C ASP F 201 39 769 ] 16 838 9355 1 00122 99 F ATOM 19731 CB THR F 211 52417 12904 4723 1006595 F

ATOM 19647 O ASP F 201 39314 : 15 720 9 113 1 0012299 F ATOM 19732 OGl THR F 211 51579 13718 3896 1006595 F

ATOM 19648 N TRP F 202 40 160 : 17 676 8 397 1 00104 82 F ATOM 19733 CG2 THR F 211 52725 13658 6007 1006595 F

ATOM 19649 CA TRP F 202 40 042 17 323 6 980 1 00104 82 F ATOM 19734 C THR F 211 54549 11619 4796 1007483 F

ATOM 19650 CB TRP F 202 39 859 18 581 6 128 1 00 9726 F ATOM 19735 O THR F211 54143 10481 50141007483 F

ATOM 19651 CG TRP F 202 40 916 19 634 6 321 1 00 97 26 F ATOM 19736 N PRO F 212 55738 12050 5245 1008146 F

ATOM 19652 CD2 TRP F 202 42 160 19 745 5 618 1 009726 F ATOM 19737 CD PRO F 212 56262 13423 5110 1006617 F

ATOM 19653 CE2 TRP F 202 42 807 20 910 6 094 1 009726 F ATOM 19738 CA PRO F 212 56649 11209 6040 1008146 F

ATOM 19654 CE3 TRP F 202 42 791 18 976 4 633 1 009726 F ATOM 19739 CB PRO F 212 57681 12210 6549 1006617 F

ATOM 19655 CDl TRP F 202 40 864 20 700 7 173 1 009726 F ATOM 19740 CG PRO F 212 57721 13242 5433 1006617 F

ATOM 19656 NEl TRP F 202 41 994 21 473 7 040 1 0097 26 F ATOM 19741 C PRO F 212 55996 10415 7175 1008146 F

ATOM 19657 CZ2 TRP F 202 44052 21 324 5 616 1 00 97 26 F ATOM 19742 O PRO F 212 55113 10922 7863 1008146 F

ATOM 19658 CZ3 TRP F 202 44 031 19 388 4 159 1 0097 26 F ATOM 19743 N GLY F 213 56438 9172 7366 1007747 F

ATOM 19659 CH2 TRP F 202 44 647 20 553 4 652 1 009726 F ATOM 19744 CA GLY F 213 55898 8331 8429 1007747 F

ATOM 19660 C TRP F 202 41 188 1 16 518 6384 1 00104 82 F ATOM 19745 C GLY F 2I3 56571 8576 9775 1007747 F

ATOM 19661 O TRP F 202 41 099 : 16 060 5 248 1 00104 82 F ATOM 19746 O GLY F 213 57467 9417 9881 1007747 F

ATOM 19662 N PHE F 203 42 259 16 338 7 145 1 00112 60 F ATOM 19747 N ASN F 214 56156 7839 10803 1009663 F

ATOM 19663 CA PHE F 203 43 420 15 615 6652 1 0011260 F ATOM 19748 CA ASN F 214 56716 7999 12151 1009663 F

ATOM 19664 CB PHE F 203 44 687 16 361 7 072 1 00 94 83 F ATOM 19749 CB ASN F 214 58214 7702 12194 10010527 F

ATOM 19665 CG PHE F 203 45 945 15 824 6 458 1 00 94 83 F ATOM 19750 CG ASN F 214 58598 6549 11324 1009944 F

ATOM 19666 CDl PHE F 203 46 193 15 984 5 098 : 1 0094 83 F ATOM 19751 ODl ASN F 214 57749 5763 10917 1009944 F

ATOM 19667 CD2 PHE F 203 46 892 15 170 7241 1 0094 83 F ATOM 19752 ND2 ASN F 214 59888 6429 11032 1009944 F

ATOM 19668 CEl PHE F 203 47 367 15 504 4 525 1 0094 83 F ATOM 19753 C ASN F 214 56526 9437 12574 1009663 F

ATOM 19669 CE2 PHE F 203 48068 14 686 6680 1 0094 83 F ATOM 19754 O ASN F 214 57473 10091 13025 1009663 F

ATOM 19670 CZ PHE F 203 48 306 14 855 5 319 1 00 94 83 F ATOM 19755 N ASP F 215 55302 9930 12423 100 SO 65 F

ATOM 19671 C PHE F 203 43 505 : 14 172 7 130 1 00112 60 F ATOM 19756 CA ASP F 215 55000 11303 12777 1008065 F

ATOM 19672 O PHE F 203 43 817 13 917 8292 1 00112 60 F ATOM 19757 CB ASP F 215 54912 11453 14292 10017165 F

ATOM 19673 N ASN F 204 43 212 13 232 6237 1 00 80 80 F ATOM 19758 CG ASP F 215 53899 10518 14899 1009303 F

ATOM 19674 CA ASN F 204 43 312 1 1 813 6 572 1 00 80 80 F ATOM 19759 ODl ASP F 215 52723 10557 14480 1009303 F

ATOM 19675 CB ASN F 204 42 265 10 982 5 806 1 00113 91 F ATOM 19760 OD2 ASP F 215 54282 9741 15793 1009303 F

ATOM 19676 CG ASN F 204 42 505 9476 5 922 1 00113 91 F ATOM 19761 C ASP F 215 56085 12210 12223 1008065 F

ATOM 19677 ODl ASN F 204 43 51' ' 8 977 5 441 1 00113 91 F ATOM 19762 O ASP F 215 56825 12852 12974 1008065 F

ATOM 19678 ND2 ASN F 204 41 59f i 8 756 6 578 1 001 13 91 F ATOM 19763 N TYR F 216 5619012224 10898 1005358 F

ATOM 19679 C ASN F 204 44722 11 445 6 128 1 00 80 80 F ATOM 19764 CA TYR F 216 57156 13062 10198 1005358 F

ATOM 19680 O ASN F 204 44969 11 241 4 946 1 00 80 80 F ATOM 19765 CB TYR F 216 56770 14540 10349 10010715 F

ATOM 19681 N ILE F 205 45 651 11 381 ' 7 076 1 00 98 70 F ATOM 19766 CG TYR F 216 55337 14844 9972 1008590 F

ATOM 19682 CA ILE F 205 47041 11 071 6757 1 0098 70 F ATOM 19767 CDl TYR F 216 54278 14373 107441008590 F

ATOM 19683 CB ILE F 205 47916 11 054 8026 1 00 68 31 F ATOM 19768 CEl TYR F 216 52957 14625 10391 1008590 F

ATOM 19684 CG2 ILE F 205 47 792 9 716 8729 1 00 68 31 F ATOM 19769 CD2 TYR F 216 55039 15584 8829 1008590 F

ATOM 19685 CGl ILE F 205 49 372 11 314 7 644 1 00 68 31 F ATOM 19770 CE2 TYR F 216 53721 15845 8466 1008590 F

ATOM 19686 CDl ILE F 205 50230 11 758 8 807 1 00 68 31 F ATOM 19771 CZ TYR F 216 52683 15360 9252 1008590 F

ATOM 19687 C ILE F 205 47 244 < 1 758 6001 1 0098 70 : F ATOM 19772 OH TYR F 216 51377 15607 8894 1008590 F

ATOM 19688 O ILE F 205 48298 ' ) 541 5404 1 009870 F ATOM 19773 C TYR F 216 58598 12878106501005358 F

ATOM 19689 N SER F 206 46 243 8 884 i 6 024 1 00 99 02 F ATOM 19774 O TYR F 216 59370 13845 10658 1005358 F

ATOM 19690 CA SER F 206 46 345 7 612 5316 1 0099 02 F ATOM 19775 N ASN F 217 58962 11647 11013 1007471 F

ATOM 19691 CB SER F 206 45 281 6 634 5 807 1 0097 09 F ATOM 19776 CA ASN F 217 60320 11351 11471 1007471 F

ATOM 19692 OG SER F 206 45 511 6292 7 159 1 00 9709 F ATOM 19777 CB ASN F 217 61311 11469 10311 1008862 F

ATOM 19693 C SER F 206 46 184 7 825 : I 818 1 00 99 02 F ATOM 19778 CG ASN F 217 61020 10492 9195 1008335 F

ATOM 19694 O SER F 206 46 605 7000 : 3 016 1 009902 F ATOM 19779 ODl ASN F 217 6083410885 80401008335 F

ATOM 19695 N ARG F 207 45 570 8 940 3443 1 00 86 38 F ATOM 19780 ND2 ASN F 217 60980 9206 9531 1008335 F

ATOM 19696 CA ARG F 207 45 369 9 250 2 038 1 00 8638 F ATOM 19781 C ASN F 217 60706 12340 12563 1007471 F

ATOM 19697 CB ARG F 207 44032 9 969 1 832 1 00103 28 F ATOM 19782 O ASN F 217 61858 12774 12646 1007471 F

ATOM 19698 CG ARG F 207 42 828 9 052 1 953 1 00103 28 F ATOM 19783 N PHE F 218 59739 12692 13406 1007858 F

ATOM 19699 CD ARG F 207 41 678 9 535 1 088 1 00103 28 F ATOM 19784 CA PHE F 218 59989 13658 14467 1007858 F

ATOM 19700 NE ARG F 207 40 981 10 685 1 656 1 00103 28 F ATOM 19785 CB PHE F 218 58722 13947 15262 1007153 F

ATOM 19701 CZ ARG F 207 40 312 11 576 0 932 1 00103 28 F ATOM 197S6 CG PHE F 2I8 58910 15016 16285 1006805 F

ATOM 19702 NHl ARG F 207 40257 11 45 1 0 387 1 00103 28 F ATOM 19787 CDl PHE F 218 58838 16358 15931 1006805 F

ATOM 19703 NH2 ARG F 207 39 690 12 586 1 525 1 00103 2! i F ATOM 19788 CD2 PHE F 218 59228 14685 17595 1006805 F

ATOM 19704 C ARG F 207 46 502 10 100 1 486 1 00 8638 F ATOM 19789 CEl PHE F 218 59084 17363 16873 1006805 F

ATOM 19705 O ARG F 207 46406 10 611 0374 1 00 8638 F ATOM 19790 CE2 PHE F 218 59478 15680 18543 1006805 F

ATOM 19706 N SER F 208 47 574 10253 2 263 1 00 73 01 F ATOM 19791 CZ PHE F 218 59405 17022 18177 1006805 F

ATOM 19707 CA SER F 208 48728 11 038 1 825 1 0073 01 F ATOM 19792 C PHE F218 6108213261 15442 1007858 F

ATOM 19708 CB SER F 208 48853 12 324 2 631 1 00 87 33 F ATOM 19793 O PHE F 218 62002 14033 15690 1007858 F

ATOM 19709 OG SER F 208 49 916 13 106 2 123 1 00 8733 F ATOM 19794 N ASN F 219 6097412068 16014 1007157 F

ATOM 19710 C SER F 208 50 008 [0232 1 965 1 00 73 01 F ATOM 19795 CA ASN F 219 61983 11628 16963 1007157 F

ATOM 19711 O SER F 208 50 853 10 515 2 814 1 00 73 01 F ATOM 19796 CB ASN F 219 61716 10195 17415 I 007118 F

ATOM 19712 N PRO F 209 50 166 9219 1 110 1 [ 00 69 79 F ATOM 19797 CG ASN F 219 60358 10037 18059 1006281 F

ATOM 19713 CD PRO F 209 49232 8 966 0002 1 008890 F ATOM 19798 ODl ASN F 219 59875 10940187441006281 F

ATOM 19714 CA PRO F 209 51 299 8 297 1 041 1 00 69 79 F ATOM 19799 ND2 ASN F 219 59738 888417856 1006281 F

ATOM 19715 CB PRO F 209 51 088 7 598 0297 1 00 8890 F ATOM 19800 C ASN F 219 63362 11727 16334 1007157 F

ATOM 19716 CG PRO F 209 49 616 7 574 0420 1 00 8890 F ATOM 19801 O ASN F 219 64301 12210 16968 1007157 F

ATOM 19717 C PRO F 209 52 664 8 963 1 102 1 I 00 69 79 F ATOM 19802 N PHE F 220 63481 11281 15084 1005880 F

ATOM 19718 O PRO F 209 53 633 8 363 1 567 ; I 00 69 79 F ATOM 19803 CA PHE F 220 64762 11341 14387 1005880 F

ATOM 19719 N HIS F 210 52744 I 0202 i 0634 1 . 006708 F ATOM 19804 CB PHE F 220 646241082712951 1006619 F

ATOM 19720 CA HIS F 210 54021 10 885 0 605 1 0067 08 F ATOM 19805 CG PHE F 220 65816 11146 12084 1005917 F

ATOM 19721 CB HIS F 210 54 158 11 597 0733 1 0068 07 F ATOM 19806 CDl PHE F 220 66953 10338 12110 1005917 F

ATOM 19722 CG HIS F 210 54 167 10 655 1 894 1 00 68 07 F ATOM 19807 CD2 PHE F 220 65823 12293 11284 1005917 F

ATOM 19723 CD2 HIS F210 53 223 10 372 2 823 1 00 6807 F ATOM 19808 CEl PHE F 220 68081 10665 11356 1005917 F

ATOM 19724 NDl HIS F 210 55 222 9 804 2 149 1 0068 07 F ATOM 19809 CE2 PHE F 220 6694612630 10528 1005917 F

ATOM 19725 CEl HIS F 210 54927 9 038 3 185 1 00 68 07 F ATOM 19810 CZ PHE F 220 68079 11813 10564 1005917 F

ATOM 19726 NE2 HIS F 210 53 720 9 362 3 611 1 0068 07 F ATOM 19811 C PHE F 220 65308 12769 14345 1005880 F 65251/C766

ATOM 19812 O PHE F 220 66433 13027 14774 1005880 F ATOM 19897 CG GLU F 230 73380 19879 22728 100111 14 F

ATOM 19813 N TRP F 221 64507 13689 13813 1007044 F ATOM 19898 CD GLU F 230 73395 18525 23407 100111 14 F

ATOM 19814 CA TRP F 221 64924 15082 13690 1007044 F ATOM 19899 OEl GLU F 230 74415 18201 24052 100111 14 F

ATOM 19815 CB TRP F 221 63898 15865 12860 1006379 F ATOM 19900 OE2 GLU F 230 72386 17790 23306 100111 14 F

ATOM 19816 CG TRP F 221 63954 15528 11399 1005694 F ATOM 19901 C GLU F 230 76003 21809 20655 1009144 F

ATOM 19817 CD2 TRP F 221 65070 15726 10526 1005694 F ATOM 19902 O GLU F 230 76757 22591 21229 1009144 F

ATOM 19818 CE2 TRP F221 64705 15219 9262 1005694 F ATOM 19903 N GLU F 231 76330 21 195 19523 1008627 F

ATOM 19819 CE3 TRP F 221 66349 16282 10692 1005694 F ATOM 19904 CA GLU F 231 77624 21415 18880 1008627 F

ATOM 19820 CD 1 TRP F 221 62979 14929 10650 1005694 F ATOM 19905 CB GLU F 231 77742 20552 17620 10015153 F

ATOM 19821 NEl TRP F 221 63424 14739 9364 1005694 F ATOM 19906 CG GLU F 231 77529 19068 17855 10012777 F

ATOM 19822 CZ2 TRP F 221 65570 15247 8170 1005694 F ATOM 19907 CD GLU F 231 78626 18443 18692 10012777 F

ATOM 19823 CZ3 TRP F 221 67208 16310 9609 1005694 F ATOM 19908 OEl GLU F 231 78891 18950 19801 10012777 F

ATOM 19824 CH2 TRP F221 66814 15794 8361 1005694 F ATOM 19909 OE2 GLU F231 79221 17441 18242 10012777 F

ATOM 19825 C TRP F 221 65163 15781 15022 1007044 F ATOM 19910 C GLU F 231 77770 22890 18498 1008627 F

ATOM 19826 O TRP F 221 66184 16446 15209 1007044 F ATOM 19911 O GLU F 231 78812 23509 18726 1008627 F

ATOM 19827 N TYR F 222 64224 15636 15950 1006501 F ATOM 19912 N ILE F 232 76716 23446 17912 10012262 F

ATOM 19828 CA TYR F 222 64371 16266 17254 1006501 F ATOM 19913 CA ILE F 232 76721 24842 17495 10012262 F

ATOM 19829 CB TYR F 222 63313 15756 18227 10010548 F ATOM 19914 CB ILE F 232 75370 25229 16843 10012423 F

ATOM 19830 CG TYR F 222 63600 16204 19631 10010405 F ATOM 19915 CG2 ILE F 232 75246 26735 16743 1009428 F

ATOM 19831 CDl TYR F 222 63331 17507 20030 10010405 F ATOM 19916 CGl ILE F 232 75260 24602 15452 1009428 F

ATOM 19832 CE I TYR F 222 63673 17951 21295 10010405 F ATOM 19917 CDl ILE F 232 73957 24925 14741 1009428 F

ATOM 19833 CD2 TYR F 222 64219 15350 20538 10010405 F ATOM 19918 C ILE F 232 76999 25789 18660 10012262 F

ATOM 19834 CE2 TYR F 222 64570 15781 21805 10010405 F ATOM 19919 O ILE F 232 77627 26833 18485 10012262 F

ATOM 19835 CZ TYR F 222 64296 17081 22179 10010405 F ATOM 19920 N ASN F 233 76539 25423 19851 10010377 F

ATOM 19836 OH TYR F 222 64657 17511 23435 10010405 F ATOM 19921 CA ASN F 233 76740 26274 21015 10010377 F

ATOM 19837 C TYR F 222 65742 15944 17824 1006501 F ATOM 19922 CB ASN F 233 75649 26017 22054 10011686 F

ATOM 19838 O TYR F 222 66506 16832 18202 1006501 F ATOM 19923 CG ASN F 233 74294 26530 21611 10010578 F

ATOM 19839 N SER F 223 66036 14653 17876 I 008880 F ATOM 19924 ODl ASN F 233 74202 27531 20900 10010578 F

ATOM 19840 CA SER F 223 67294 14182 18406 1008880 F ATOM 19925 ND2 ASN F 233 73233 25858 22046 10010578 F

ATOM 19841 CB SER F 223 67302 12665 18425 1006243 F ATOM 19926 C ASN F 233 78109 26178 21682 10010377 F

ATOM 19842 OG SER F 223 68582 12200 18795 1006105 F ATOM 19927 O ASN F 233 78433 27000 22540 10010377 F

ATOM 19843 C SER F 223 68511 14685 17645 1008880 F ATOM 19928 N LYS F 234 78914 25190 21302 10010562 F

ATOM 19844 O SER F 223 69459 15179 18253 1008880 F ATOM 19929 CA LYS F 234 80239 25057 21894 10010562 F

ATOM 19845 N LEU F 224 68493 14566 16321 1006260 F ATOM 19930 CB LYS F 234 80875 23731 21490 1008295 F

ATOM 19846 CA LEU F 224 69630 15000 15525 1006260 ATOM 19931 CG LYS F 234 80248 22560 22226 1008295 F

ATOM 19847 CB LEU F 224 69491 14521 14080 1008383 F ATOM 19932 CD LYS F 234 80900 21229 21890 1008295 F

ATOM 19848 CG LEU F 224 70647 14932 13162 1006107 F ATOM 19933 CE LYS F 234 80257 20107 22703 1008295 F

ATOM 19849 CDl LEU F 224 71985 14487 13740 1006107 F ATOM 19934 NZ LYS F 234 80751 18755 22321 1008295 F

ATOM 19850 CD2 LEU F 224 70419 14326 11794 1006107 F ATOM 19935 C LYS F 234 81 127 26239 21518 10010562 F

ATOM 19851 C LEU F 224 69804 16507 15557 1006260 F ATOM 19936 O LYS F 234 81804 26796 22379 10010562 F

ATOM 19852 O LEU F 224 70928 17009 15464 1006260 F ATOM 19937 N ASN F 235 81 141 26624 20246 10012337 F

ATOM 19853 N MET F 225 68695 17230 15684 1007495 F ATOM 19938 CA ASN F 235 81917 27797 19849 10012337 F

ATOM 19854 CA MET F 225 68761 18682 15745 1007495 F ATOM 19939 CB ASN F 235 82101 27870 18326 10013612 F

ATOM 19855 CB MET F 225 67399 19283 15462 10011016 F ATOM 19940 CG ASN F 235 82785 29161 17880 10013612 F

ATOM 19856 CG MET F 225 66986 19082 14038 1007888 F ATOM 19941 ODl ASN F 235 82451 30238 18376 10013612 F

ATOM 19857 SD MET F 225 65487 19943 13649 1007888 F ATOM 19942 ND2 ASN F 235 83728 29068 16942 10013612 F

ATOM 19858 CE MET F 225 66032 21663 13906 1007888 F ATOM 19943 C ASN F 235 81013 28931 20327 10012337 F

ATOM 19859 C MET F 225 69245 19099 17120 1007495 F ATOM 19944 O ASN F 235 79938 29152 19773 10012337 F

ATOM 19860 O MET F 225 69972 20080 17265 1007495 F ATOM 19945 N ASP F 236 81442 29635 21366 10014723 F

ATOM 19861 N LYS F 226 68837 18349 18134 1008452 F ATOM 19946 CA ASP F 236 80645 30710 21946 10014723 F

ATOM 19862 CA LYS F 226 69272 18639 19486 1008452 F ATOM 19947 CB ASP F 236 81356 31251 23191 10018048 F

ATOM 19863 CB LYS F 226 68661 17635 20460 10014011 F ATOM 19948 CG ASP F 236 80398 31888 24178 10018048 F

ATOM 19864 CG LYS F 226 69061 1786021899 1009157 F ATOM 19949 ODl ASP F 236 79866 32976 23879 10018048 F

ATOM 19865 CD LYS F 226 68553 16736 22770 1009157 F ATOM 19950 OD2 ASP F 236 80173 31293 25254 10018048 F

ATOM 19866 CE LYS F 226 69159 16812 24158 1009157 F ATOM 19951 C ASP F 236 80276 31865 21009 10014723 F

ATOM 19867 NZ LYS F 226 68701 15676 25002 1009157 F ATOM 19952 O ASP F 236 79491 32735 21382 10014723 F

ATOM 19868 C LYS F 226 70798 18527 19492 1008452 F ATOM 19953 N SER F 237 80823 31879 19797 10012788 F

ATOM 19869 O LYS F 226 71492 19397 20015 1008452 F ATOM 19954 CA SER F 237 80511 32952 18851 10012788 F

ATOM 19870 N GLU F 227 71310 17456 18888 1007809 F ATOM 19955 CB SER F 237 81739 33303 18002 1008624 F

ATOM 19871 CA GLU F 227 72749 17226 18807 1007809 F ATOM 19956 OG SER F 237 81973 32327 17003 1008624 F

ATOM 19872 CB GLU F 227 73045 15938 18034 10014066 F ATOM 19957 C SER F 237 79351 32578 17928 10012788 F

ATOM 19873 CG GLU F 227 74521 15569 18010 10011646 F ATOM 19958 O SER F 237 78999 33335 17021 10012788 F

ATOM 19874 CD GLU F 227 74850 14506 16978 10011646 F ATOM 19959 N THR F 238 78763 31408 18161 10012054 F

ATOM 19875 OEl GLU F 227 74186 13444 16967 10011646 F ATOM 19960 CA THR F 238 77643 30929 17355 10012054 F

ATOM 19876 OE2 GLU F 227 75782 14734 16180 10011646 F ATOM 19961 CB THR F 238 77981 29607 16642 1009952 F

ATOM 19877 C GLU F 227 73427 18390 18098 1007809 F ATOM 19962 OGl THR F 238 79279 29702 16047 1009952 F

ATOM 19878 O GLU F 227 74432 18913 18568 1007809 F ATOM 19963 CG2 THR F 238 76962 29321 15548 1009952 F

ATOM 19879 N THR F 228 72868 18786 16958 1009423 F ATOM 19964 C THR F 238 76436 30679 18245 10012054 F

ATOM 19880 CA THR F 228 73413 19881 16168 1009423 F ATOM 19965 O THR F 238 75298 30718 17781 10012054 F

ATOM 19881 CB THR F 228 72609 20085 14877 10010040 F ATOM 19966 N LYS F 239 76702 30417 19522 10010795 F

ATOM 19882 OGl THR F 228 72622 18875 14113 1008639 F ATOM 19967 CA LYS F 239 75664 30149 20513 I 0010795 F

ATOM 19883 CG2 THR F 228 73212 21211 14048 1008639 F ATOM 19968 CB LYS F 239 76082 30724 21872 10014796 F

ATOM 19884 C THR F 228 73425 21 199 16930 1009423 F ATOM 19969 CG LYS F 239 75106 30431 23005 10014796 F

ATOM 19885 O THR F 228 74372 21978 16818 1009423 F ATOM 19970 CD LYS F 239 75700 30796 24358 10014796 F

ATOM 19886 N LEU F 229 72369 21455 17695 1008400 F ATOM 19971 CE LYS F 239 76928 29953 24666 10014796 F

ATOM 19887 CA LEU F 229 72293 22690 18454 1008400 F ATOM 19972 NZ LYS F 239 77521 30300 25987 10014796 F

ATOM 19888 CB LEU F 229 70912 22838 19089 1009547 F ATOM 19973 C LYS F 239 74311 30714 20095 10010795 F

ATOM 19889 CG LEU F 229 70669 24126 19878 1006735 F ATOM 19974 O LYS F 239 74174 31911 19831 10010795 F

ATOM 19890 CDl LEU F 229 71224 25337 19131 1006735 F ATOM 19975 N THR F 240 73313 29840 20031 1007305 F

ATOM 19891 CD2 LEU F 229 69171 24270 20119 1006735 F ATOM 19976 CA THR F 240 71974 30242 19626 1007305 F

ATOM 19892 C LEU F 229 73379 22724 19521 1008400 F ATOM 19977 CB THR F 240 71666 29791 18189 10010596 F

ATOM 19893 O LEU F 229 74016 23755 19725 1008400 F ATOM 19978 OGl THR F 240 72690 30264 17305 10010596 F

ATOM 19894 N GLU F 230 73600 21594 20188 1009144 F ATOM 19979 CG2 THR F 240 70322 30341 17742 10010596 F

ATOM 19895 CA GLU F 230 74621 21509 21225 1009144 F ATOM 19980 C THR F 240 70897 29661 20525 1007305 F

ATOM 19896 CB GLU F 230 74607 20124 21873 10014668 F ATOM 19981 O THR F 240 71085 28616 21 156 1007305 F 65251/C766

ATOM 19982 N THR F 241 69 760 30350 20552 1 00 85 16 F ATOM 20067 CG2 THR F 252 52838 31918 -6298 1008221 F

1 ATOM 19983 CA THR F 241 68 609 29 955 21 350 1 00 85 16 F ATOM 20068 C THR F 252 52227 29939 -8505 1005837 F

ATOM 19984 CB THR F 241 67 545 31 059 21 359 1 00124 68 F ATOM 20069 O THR F 252 53165 30375 -9174 1005837 F ATOM 19985 OG1 THR F 241 68 165 32 317 21 650 1 00 84 38 F ATOM 20070 N GLY F 253 51003 29787 -9000 1007039 F ATOM 19986 CG2 THR F 241 66467 30752 22 393 1 00 84 38 F ATOM 20071 CA GLY F 253 50757 30100-10396 1007039 F

ATOM 19987 C THR F 241 67 951 28 715 20 775 1 00 85 16 F ATOM 20072 C GLY F 253 51594 29172-11270 1007039 F

ATOM 19988 O THR F 241 67 587 27790 21 505 1 00 85 16 F ATOM 20073 O GLY F 253 51575 27952-11085 1007039 F

ATOM 19989 N SER F 242 67 799 28 710 19 454 1 00110 51 F ATOM 20074 N LEU F 254 52332 29740-12220 1005787 F

ATOM 19990 CA SER F 242 67 143 27 605 18 774 1 00110 51 F ATOM 20075 CA LEU F 254 53180 28940-13092 1005787 F

ATOM 19991 CB SER F 242 65 643 27 886 18 683 1 0013223 F ATOM 20076 CB LEU F 254 53612 29731 -14327 1005043 F ATOM 19992 OG SER F 242 65409 29 057 17 916 1 00104 75 F ATOM 20077 CG LEU F 254 52569 30083-15376 1005043 F

ATOM 19993 C SER F 242 67 669 27 309 17 374 1 00110 51 F ATOM 20078 CDl LEU F 254 53285 30691 -16570 1005043 F

ATOM 19994 O SER F 242 68459 28 064 16 805 1 00110 51 F ATOM 20079 CD2 LEU F 254 51780 28844-15772 1005043 F

ATOM 19995 N LEU F 243 67 186 26 196 16 S30 1 00 73 66 F ATOM 20080 C LEU F 254 54433 28482 -12372 1005787 F

ATOM 19996 CA LEU F 243 67551 25 730 15 506 1 00 73 66 F ATOM 20081 O LEU F 254 54985 27444 -12695 1005787 F

ATOM 19997 CB LEU F 243 68536 24 574 15 633 1 00 8049 F ATOM 20082 N LEU F 255 54893 29268-11411 1004270 F

ATOM 19998 CG LEU F 243 69240 24 151 14 353 1 00 56 62 F ATOM 20083 CA LEU F 255 56106 28928-10676 1004270 F ATOM 19999 CDl LEU F 243 70 015 25 333 13 781 1 00 56 62 F ATOM 20084 CB LEU F 255 56596 30129 -9860 1005787 F ATOM 20000 CD2 LEU F 243 70 176 22 983 14 658 1 00 56 62 F ATOM 20085 CG LEU F 255 56755 31447-10618 1005787 F

ATOM 20001 C LEU F 243 66281 25 263 14 799 1 00 73 66 F ATOM 20086 CDl LEU F 255 57311 32502 -9679 1005787 F

ATOM 20002 O LEU F 243 65 410 24 628 15 412 1 00 73 66 F ATOM 20087 CD2 LEU F 255 57677 31254-11 814 1005787 F

10 ATOM 20003 N SER F 244 66 170 25 587 13 514 1 00 72 83 F ATOM 20088 C LEU F 255 55914 27739 -9748 1004270 F

ATOM 20004 CA SER F 244 64 995 25 192 12 740 1 00 72 83 F ATOM 20089 O LEU F 255 54812 27495 -9243 1004270 F

ATOM 20005 CB SER F 244 64 092 26 401 12486 1 00116 10 F ATOM 20090 N PHE F 256 56998 26997 -9537 1006516 F

ATOM 20006 OG SER F 244 63 522 26 878 13 686 1 00118 25 F ATOM 20091 CA PHE F 256 56967 25831 -8662 1006516 F

ATOM 20007 C SER F 244 65 309 24 542 11 397 1 00 72 83 F ATOM 20092 CB PHE F 256 56256 24663 -9355 1005441 F

ATOM 20008 O SER F 244 66241 24 940 10 696 1 00 72 83 F ATOM 20093 CG PHE F 256 56988 24123 -10546 1005142 F

ATOM 20009 N LEU F 245 64 516 23 534 11 050 1 00 76 20 F ATOM 20094 CDl PHE F 256 57783 22993-10435 1005142 F

ATOM 20010 CA LEU F 245 64658 22 849 9 773 1 00 76 20 F ATOM 20095 CD2 PHE F 256 56876 24739 -11 792 1005142 F

ATOM 20011 CB LEU F 245 64 701 21 336 9 965 1 00 87 08 F ATOM 20096 CEl PHE F 256 58451 22484-11542 1005142 F

ATOM 20012 CG LEU F 245 64761 20 582 8 639 1 00 71 07 F ATOM 20097 CE2 PHE F 256 57545 24231-12909 1005142 F ATOM 20013 CDl LEU F 245 65 976 21 044 7 848 1 0071 07 F ATOM 20098 CZ PHE F 256 58331 23103-12778 1005142 F

I ^ ATOM 20014 CD2 LEU F 245 64816 19 086 8 893 1 0071 07 F ATOM 20099 C PHE F 256 58380 25435 -8254 1006516 F

ATOM 20015 C LEU F 245 63 437 23 224 8 944 1 007620 F ATOM 20100 O PHE F 256 59318 25566 -9040 1006516 F

ATOM 20016 O LEU F 245 62 330 22 750 9 204 1 00 7620 F ATOM 20101 N GLY F 257 58530 24971 -7016 1005051 F

ATOM 20017 N ILE F 246 63 636 24 090 7 960 1 00 77 06 F ATOM 20102 CA GLY F 257 59839 24576 -6526 1005051 F

ATOM 20018 CA ILE F 246 62 534 24 537 7 117 1 0077 06 F ATOM 20103 C GLY F 257 59759 23979 -5139 1005051 F

ATOM 20019 CB ILE F 246 62 603 26070 6 872 1 00 80 16 F ATOM 20104 O GLY F 257 58674 23845 -4571 1005051 F

ATOM 20020 CG2 ILE F 246 61 397 26 540 6 077 1 00 63 20 F ATOM 20105 N SER F 258 60906 23599 4593 1004805 F

ATOM 20021 CGl ILE F 246 62 642 26 807 8 208 1 00 63 20 F ATOM 20106 CA SER F 258 60951 23021 -3254 1004805 F

ATOM 20022 CDl ILE F 246 61 487 26468 9 130 1 00 63 20 F ATOM 20107 CB SER F 258 61029 21497 -3327 1005319 F

ATOM 20023 C ILE F 246 62 576 23 822 5 777 1 00 77 06 F ATOM 20108 OG SER F 258 62267 21091 -3879 1006331 F

ATOM 20024 O ILE F 246 63 550 23 943 5 032 1 00 77 06 F ATOM 20109 C SER F 258 62175 23572 -2527 1004805 F

20 ATOM 20025 N THR F 247 61 523 23 073 5 471 1 00 6020 F ATOM 20110 O SER F 258 63098 24099 -3147 1004805 F

ATOM 20026 CA THR F 247 61 471 22 356 4209 1 00 60 20 F ATOM 20111 N TYR F 259 62188 23448 -1209 1004973 F

ATOM 20027 CB THR F 247 62 011 20 923 4375 1 00 70 85 F ATOM 20112 CA TYR F 259 63302 23971 -0437 1004973 F ATOM 20028 OGl THR F 247 62206 20337 3 084 1 006809 F ATOM 20113 CB TYR F 259 63030 25432 -0068 1007086 F ATOM 20029 CG2 THR F 247 61 038 20069 5 178 1 006809 F ATOM 20114 CG TYR F 259 61695 25617 0621 1006661 F

ATOM 20030 C THR F 247 60033 22 320 3 692 1 006020 F ATOM 20115 CDl TYR F 259 61540 25339 1983 1006661 F

ATOM 20031 O THR F 247 59 089 22 302 4471 1 00 6020 F ATOM 20116 CEl TYR F 259 60292 25403 2590 1006661 F

ATOM 20032 N GLY F 248 59 871 22 322 2 376 1 00 57 82 F ATOM 20117 CD2 TYR F 259 60562 25975 -0110 1006661 F

ATOM 20033 CA GLY F 248 58 539 22 304 1 799 1 0057 82 F ATOM 20118 CE2 TYR F 259 59310 26038 0489 1006661 F

ATOM 20034 C GLY F 248 58 575 22 655 0 322 1 0057 82 F ATOM 20119 CZ TYR F 259 59181 25746 1 835 1006661 F

ATOM 20035 O GLY F 248 59 650 22 754 -0273 1 00 57 82 F ATOM 20120 OH TYR F 259 57928 25753 2401 1006661 F

ATOM 20036 N CYS F 249 57411 22 848 -0 283 1 00 6795 F ATOM 20121 C TYR F 259 63536 23 161 0826 1004973 F

25 ATOM 20037 CA CYS F 249 57 370 23 184 -1 700 1 00 67 95 F ATOM 20122 O TYR F 259 62667 22401 1284 1004973 F

ATOM 20038 CB CYS F 249 57220 21 921 -2 547 1 0049 94 F ATOM 20123 N GLY F 260 64729 23338 I 384 1006495 F

ATOM 20039 SG CYS F 249 55 579 21 181 -2 458 1 00 68 71 F ATOM 20124 CA GLY F 260 65104 22646 2600 1006495 F

ATOM 20040 C CYS F 249 56221 24 134 -1 997 1 0067 95 F ATOM 20125 C GLY F 260 66337 23331 3135 1006495 F

ATOM 20041 O CYS F 249 55471 24 521 -1 098 1 0067 95 F ATOM 20126 O GLY F 260 67430 23185 2594 1006495 F

ATOM 20042 N TYR F 250 56076 24 494 -3 267 1 00 6752 F ATOM 20127 N TYR F 261 66165 24112 4187 1006848 F

ATOM 20043 CA TYR F 250 55 027 25 416 -3 674 1 00 67 52 F ATOM 20128 CA TYR F 261 67295 24810 4759 1006848 F

ATOM 20044 CB TYR F 250 55 473 26 835 -3 386 1 00 51 67 F ATOM 20129 CB TYR F 261 67371 26232 4200 1009196 F

ATOM 20045 CG TYR F 250 56 700 27 221 -4 175 1 0042 02 F ATOM 20130 CG TYR F 261 66160 27089 4492 1007575 F ATOM 20046 CDl TYR F 250 56588 27 814 -5 427 1 004202 F ATOM 20131 CDl TYR F 261 66057 27817 5677 1007575 F ATOM 20047 CEl TYR F 250 57716 28 167 -6 157 1 0042 02 F ATOM 20132 CEl TYR F 261 64962 28642 5926 1007575 F

30 ATOM 20048 CD2 TYR F 250 57977 26 982 -3 668 1 004202 F ATOM 20133 CD2 TYR F 261 65130 27201 3569 1007575 F

ATOM 20049 CE2 TYR F 250 59 114 27 324 4384 1 0042 02 F ATOM 20134 CE2 TYR F 261 64029 28022 3811 1007575 F

ATOM 20050 CZ TYR F 250 58 979 27 915 -5 624 1 00 42 02 F ATOM 20135 CZ TYR F 261 63956 28741 4987 1007575 F

ATOM 20051 OH TYR F 250 60 106 28 247 -6338 1 0042 02 F ATOM 20136 OH TYR F 261 62886 29578 5198 1007575 F

ATOM 20052 C TYR F 250 54676 25 327 -5 147 1 00 6752 F ATOM 20137 C TYR F 261 67203 24834 6274 1006848 F

ATOM 20053 O TYR F 250 55486 24 917 -5 976 1 00 67 52 ATOM 20138 O TYR F 261 66147 24547 6865 1006848 F

ATOM 20054 N GLU F 251 53 448 25 728 -5 446 1 00 83 80 F ATOM 20139 N VAL F 262 68331 25167 6892 1007087 F

ATOM 20055 CA GLU F 251 52 927 25 786 -6798 1 0083 80 F ATOM 20140 CA VAL F 262 68440 25241 8340 1007087 F

ATOM 20056 CB GLU F 251 51 967 24 633 -7072 1 00145 03 F ATOM 20141 CB VAL F 262 69593 24345 8852 1008086 F

ATOM 20057 CG GLU F 251 52 502 23 662 -8 106 1 00 98 65 F ATOM 20142 CGl VAL F 262 69857 24622 10319 1007235 F

ATOM 20058 CD GLU F 251 51 488 22 606 -8 510 1 00 98 65 F ATOM 20143 CG2 VAL F 262 69243 22876 8647 1007235 F

35 ATOM 20059 OEl GLU F 251 50 374 22 978 -8 949 1 0098 65 F ATOM 20144 C VAL F 262 68729 26667 8762 1007087 F

ATOM 20060 OE2 GLU F 251 51 810 21 403 -8 395 1 0098 65 F ATOM 20145 O VAL F 262 69716 27253 8322 1007087 F

ATOM 20061 C GLU F 251 52 188 27 114 -6 825 1 00 83 80 F ATOM 20146 N GLU F 263 67865 27231 9601 1008287 F

ATOM 20062 O GLU F251 50970 27 172 -6651 1 0083 80 F ATOM 20147 CA GLU F 263 6808428582 10093 1008287 F

ATOM 20063 N THR F 252 52 957 28 184 -7000 1 00 58 37 F ATOM 20148 CB GLU F 263 66952 29527 9679 10011519 F

ATOM 20064 CA THR F 252 52 432 29 551 -7042 1 00 58 37 F ATOM 20149 CG GLU F 263 65562 29068 10056 10010179 F

ATOM 20065 CB THR F 252 53 439 30 537 -6402 1 00 82 21 F ATOM 20150 CD GLU F 263 64500 30067 9639 10010179 F ATOM 20066 OGl THR F 252 53 788 30 084 5 090 1 00 8221 F ATOM 20151 OEl GLU F 263 64615 30631 8523 10010179 F 65251/C766

ATOM 20152 OE2GLUF263 63547 30280 10421 10010179 F ATOM 20237 C THR F 274 70454 17866 5196 006763 F ATOM 20153 C GLU F 263 68242 28573 11606 1008287 F ATOM 20238 O THR F 274 70726 16662 -5260 1006763 F

ATOM 20154 O GLU F 263 67831 27635 12305 1008287 F ATOM 20239 N GLY F 275 71040 18784 -5958 1006644 F

ATOM 20155 N THR F 264 68851 29642 12094 10013963 F ATOM 20240 CA GLY F 275 72050 18405 -6926 1006644 F

ATOM 20156 CA THRF264 6913729821 13502 10013963 F ATOM 20241 C GLY F 275 73329 17898 -6292 1006644 F

ATOM 20157 CB THR F 264 7066429997 13669 10010434 F ATOM 20242 O GLY F 275 73683 16736 -6459 1006644 F ATOM 20158 OG1THRF264 7123728754 14084 1008327 F ATOM 20243 N ASP F 276 74014 18769 5555 006753 F ATOM 20159 CG2 THR F 264 71002 31084 14651 1008327 F ATOM 20244 CA ASP F 276 75275 18435 -4892 1006753 F

ATOM 20160 C THRF264 68385 31042 14009 10013963 F ATOM 20245 CB ASP F 276 75918 19711 -4354 10017774 F

ATOM 20161 O THRF264 67857 31817 13217 10013963 F ATOM 20246 CG ASP F 276 75976 20808 -5389 10015674 F ATOM 20162 N ALAF265 6831431207 15324 10010816 F ATOM 20247 ODl ASP F 276 7674C 20662 -6368 10015674 F

ATOM 20163 CA ALAF265 67632 32365 15884 10010816 F ATOM 20248 OD2 ASP F 276 7524S 21811 -5227 10015674 F

ATOM 20164 CB ALA F 265 6765732311 17410 10010110 F ATOM 20249 C ASP F 276 75134 17434 - 3746 006753 F

ATOM 20165 C ALAF265 6834633620 15382 10010816 ATOM 20250 O ASP F 276 76119 16827 3331 006753 F

ATOM 20166 O ALAF265 67765 34704 15342 10010816 F ATOM 20251 N LYS F 277 73916 17264 3235 007031 F

ATOM 20167 N ASNF266 69605 33452 14984 10010059 F ATOM 20252 CA LYS F 277 73666 16354 -2120 1007031 F

ATOM 20168 CA ASN F 266 70420 34553 14479 10010059 F ATOM 20253 CB LYS F 277 73975 14918 -2533 1008910 F

ATOM 20169 CB ASNF266 71903 34284 14735 10015850 F ATOM 20254 CG LYS F 277 73026 14375 -3587 1007431 F

ATOM 20170 CG ASN F 266 72197 34004 16186 10010035 F ATOM 20255 CD LYS F 277 73563 13093 -4202 1007431 F ATOM 20171 OD1 ASNF266 71815 34772 17067 10010035 F ATOM 20256 CE LYS F 277 72597 12483 -5211 1007431 F ATOM 20172 ND2 ASN F 266 7288432900 16448 10010035 F ATOM 20257 NZ LYS F 277 71428 11825 -4555 1007431 F ATOM 20173 C ASNF266 70215 34791 12991 10010059 F ATOM 20258 C LYS F 277 74500 16756 0902 007031 F

ATOM 20174 O ASNF266 70633 35821 12463 10010059 F ATOM 20259 O LYS F 277 75187 15934 0300 007031 F

ATOM 20175 N GLYF267 69583 33835 12315 10012975 F ATOM 20260 N ARG F 278 74420 18036 -0552 1007713 F

ATOM 20176 CA GLY F 267 6933633984 10891 10012975 F ATOM 20261 CA ARG F 278 75145 18586 0580 1007713 F

ATOM 20177 C GLYF267 6966732753 10069 10012975 F ATOM 20262 CB ARG F 278 76611 18727 0219 10011771 F

ATOM 20178 O GLYF267 70205 31779 10595 10012975 F ATOM 20263 CG ARG F 278 76860 19835 -0779 10010234 F

ATOM 20179 N PRO F 268 6936632776 8760 1008573 F ATOM 20264 CD ARG F 278 78258 19783 -1333 10010234 F

ATOM 20180 CD PRO F 268 68973 33963 7981 10010667 F ATOM 20265 NE ARG F 278 78568 20912 -2195 10010234 F

ATOM 20181 CA PRO F 268 69638 31646 7869 1008573 F ATOM 20266 CZ ARG F 278 79626 20970 -2998 I 0010234 F

ATOM 20182 CB PRO F 268 69366 32225 6480 10012256 F ATOM 20267 NHl ARG F 278 80486 1995 ! -305; 10010234 F

ATOM 20183 CG PROF268 69628 33688 6655 10010667 F ATOM 20268 NH2 ARG F 278 798172203 ) -376: 10010234 F ATOM 20184 C PROF268 71055 31105 8009 1008573 F ATOM 20269 C ARG F 278 74572 19967 0911 1007713 F

ATOM 20185 O PROF268 72021 31861 8068 1008573 F ATOM 20270 O ARG F 278 73798 20521 0130 1007713 F

ATOM 20186 N LEUF269 71163 29784 8050 1007759 F ATOM 20271 N PHE F 279 74949 20517 2065 006916 F

ATOM 20187 CA LEU F 269 72448 29125 8203 1007759 F ATOM 20272 CA PHE F 279 74473 21837 2457 1006916 F

ATOM 20188 CB LEUF269 7237028144 9376 10011580 F ATOM 20273 CB PHE F 279 74409 21975 3972 1007345 F

ATOM 20189 CG LEU F 269 73686 27642 9968 10081 14 F ATOM 20274 CG PHE F 279 73206 21347 4581 1005722 F

ATOM 20190 CDl LEUF269 7456728825 10343 1008114 F ATOM 20275 CDl PHE F 279 73241 20043 5055 I 005722 F

ATOM 20191 CD2LEUF269 7338826780 11 186 1008114 F ATOM 20276 CD2 PHE F 279 7202( 22067 4694 I 005722 F

ATOM 20192 C LEUF269 7291028399 6937 1007759 F ATOM 20277 CEl PHE F 279 72115 19463 5642 1005722 F

ATOM 20193 O LEU F 269 73823 28867 6250 1007759 F ATOM 20278 CE2 PHE F 279 70888 21497 5278 1005722 F

ATOM 20194 N ALAF270 72283 27262 6631 1007571 F ATOM 20279 CZ PHE F 279 70933 20190 5755 I 005722 F

ATOM 20195 CA ALA F 270 72651 26481 5448 1007571 F ATOM 20280 C PHE F 279 75398 22905 1915 1 006916 F

ATOM 20196 CB ALA F 270 73562 25332 5844 1008019 F ATOM 20281 O PHE F 279 76584 22650 1681 006916 F

ATOM 20197 C ALAF270 71463 25939 4666 1007571 F ATOM 20282 N THR F 280 74851 24102 1719 007318 F

ATOM 20198 O ALAF270 70441 25543 5231 1007571 F ATOM 20283 CA THR F 280 75628 25224 1217 1007318 F

ATOM 20199 N ARGF271 7163625897 3351 1006906 F ATOM 20284 CB THR F 280 75319 25515 -0254 10011340 F

ATOM 20200 CA ARG F 271 70611 25431 2426 1006906 F ATOM 20285 OGl THR F 280 7542 i 243Of -1011 1009392 F

ATOM 20201 CB ARG F 271 70437 26496 1343 1006786 F ATOM 20286 CG2THRF280 7630. 26539 -0805 1009392 F

ATOM 20202 CG ARG F 271 69611 26106 0160 1006098 F ATOM 20287 C THR F 280 75294 26467 2016 007318 F

ATOM 20203 CD ARG F 271 69627 27224 -0868 1006098 F ATOM 20288 O THR F 280 74128 26711 2338 007318 F

ATOM 20204 NE ARG F 271 6887928398 -0427 1006098 F ATOM 20289 N LYS F 281 76322 27249 2330 008483 F

ATOM 20205 CZ ARG F 271 6943029547 -0045 1006098 F ATOM 20290 CA LYS F 281 76151 28486 3083 1008483 F ATOM 20206 NHl ARG F 271 70751 29695 -0041 1006098 F ATOM 20291 CB LYS F 281 77479 29247 3112 10014200 F ATOM 20207 NH2 ARG F 271 68652 30554 0326 1006098 F ATOM 20292 CG LYS F 281 78264 29135 1809 I 0011794 F

ATOM 20208 C ARG F 271 7104024092 1822 1006906 F ATOM 20293 CD LYS F 281 78728 30494 1279 10011794 F

ATOM 20209 O ARGF271 7220223916 1450 1006906 F ATOM 20294 CE LYS F 281 79754 31156 2187 10011794 F

ATOM 20210 N TYR F 272 7010823146 1736 1006268 F ATOM 20295 NZ LYS F 281 80240 32451 1626 10011794 F

ATOM 20211 CA TYR F 272 7041421824 1183 1006268 F ATOM 20296 C LYS F 281 75056 29380 2486 1 008483 F

ATOM 20212 CB TYR F 272 6958020743 I 866 1007146 F ATOM 20297 O LYS F 281 74919 29476 1271 008483 F

ATOM 20213 CG TYR F 272 69906 19358 1364 1006893 F ATOM 20298 N MET F 282 74267 30016 3347 1008196 F ATOM 20214 CDl TYR F 272 71010 18664 1858 1006893 F ATOM 20299 CA MET F 282 73220 30925 2897 1008196 F

ATOM 20215 CEl TYR F 272 71338 17390 1387 1006893 F ATOM 20300 CB MET F 282 71921 30682 3654 1008101 F ATOM 20216 CD2 TYR F 272 69131 18746 0378 1006893 F ATOM 20301 CG MET F 282 71233 29395 3315 1008101 F

ATOM 20217 CE2 TYR F 272 69447 17474 -0103 1006893 F ATOM 20302 SD MET F 282 69515 29428 3865 1008101 F ATOM 20218 CZ TYRF272 70555 16799 0409 1006893 F ATOM 20303 CE MET F 282 69675 28756 5491 1008101 F

ATOM 20219 OH TYR F 272 70890 15536 -0035 1006893 F ATOM 20304 C MET F 282 73671 32360 3157 1008196 F

ATOM 20220 C TYR F 272 70155 21743 -0318 1006268 F ATOM 20305 O MET F 282 73023 33314 2730 1008196 F

ATOM 20221 O TYR F 272 69021 21945 -0769 1006268 F ATOM 20306 N THR F 283 74785 32495 3872 009418 F

ATOM 20222 N HIS F273 71198 21431 -1087 1007565 F ATOM 20307 CA THR F 283 75351 33790 4225 1009418 F

ATOM 20223 CA HIS F 273 7105821336 -2536 1007565 F ATOM 20308 CB THR F 283 75086 34112 5708 1009342 F

ATOM 20224 CB HIS F 273 7223422011 -3241 10018054 F ATOM 20309 OGl THR F 283 7367 ϊ 34241 5922 1009342 F

ATOM 20225 CG HIS F273 72171 23506 -3204 10016127 F ATOM 20310 CG2 THR F 283 75765 > 35396 6113 1009342 F

ATOM 20226 CD2HISF273 7301724424 -2681 10016127 F ATOM 20311 C THR F 283 76853 33739 4006 009418 F

ATOM 20227 NDl HISF273 71112 24218 -3728 10016127 F ATOM 20312 O THR F 283 77435 32658 3960 009418 F

ATOM 20228 CEl HIS F 273 7130925509 -3528 10016127 F ATOM 20313 N HIS F 284 77477 34905 ϊ 861 1 0013018 F ATOM 20229 NE2 HIS F 273 7245825661 2895 10016127 F ATOM 20314 CA HIS F 284 78925 34995 3671 0013018 F

ATOM 20230 C HIS F 273 70894 19914 -3029 1007565 F ATOM 20315 CB HIS F 284 79344 36467 3563 0016188 F

ATOM 20231 O HIS F 273 71757 19063 -2833 1007565 F ATOM 20316 CG HIS F 284 78921 37304 4735 0016188 F

ATOM 20232 N THR F 274 69751 19677 -3662 1006763 F ATOM 20317 CD2 HIS F 284 79646 37950 5680 10016188 F

ATOM 20233 CA THR F 274 69399 18383 -4213 1006763 F ATOM 20318 NDl HIS F 284 77597 37526 5052 10016188 F

ATOM 20234 CB THR F 274 68028 18481 -4908 1008734 F ATOM 20319 CEI HIS F 284 77525 38271 6142 10016188 F ATOM 20235 OGl THR F 274 67009 18053 -3996 1007987 F ATOM 20320 NE2 HIS F 284 78754 38542 6542 10016188 F ATOM 20236 CG2THRF274 67996 17649 -6188 1007987 F ATOM 20321 C HIS F 284 79612 34353 4880 1 0013018 F 65251/C766

ATOM 20322 O HIS F 284 80653 33705 4757 10013018 F ATOM 20407 CG LYS F 296 82954 15143 8604 10010987 F ATOM 20323 N LYS F 285 78991 34540 6042 10011659 F ATOM 20408 CD LYS F 296 84128 14270 8201 10010987 F

ATOM 20324 CA LYSF285 7947634034 7319 10011659 F ATOM 20409 CE LYS F 296 84972 13889 9406 10010987 F

ATOM 20325 CB LYSF285 78417 34278 8399 10010697 F ATOM 20410 NZ LYS F 296 86131 13027 9037 10010987 F

ATOM 20326 CG LYS F 285 78939 34969 9652 10010697 F ATOM 20411 C LYS F 296 80151 12645 9607 1006666 F

ATOM 20327 CD LYS F 285 79422 36384 9347 10010697 F ATOM 20412 O LYS F 296 80503 11595 10145 1006666 F

ATOM 20328 CE LYS F 285 79932 37081 10598 10010697 F ATOM 20413 N ASN F 297 78963 13209 9821 1006991 F

ATOM 20329 NZ LYS F 285 80383 38471 10314 10010697 F ATOM 20414 CA ASN F 297 77990 12636 10744 1006991 F

ATOM 20330 C LYS F 285 79849 32556 7315 10011659 F ATOM 20415 CB ASN F 297 76771 13551 10876 1006944 F

ATOM 20331 O LYSF285 8075232142 8041 10011659 F ATOM 20416 CG ASN F 297 75849 13136 12015 1006944 F ATOM 20332 N GLY F 286 7915431763 6507 1009653 F ATOM 20417 ODl ASN F 297 75298 12035 12016 1006944 F

ATOM 20333 CA GLY F 286 79425 30335 6455 1009653 F ATOM 20418 ND2 ASN F 297 75681 14019 12990 1006944 F

ATOM 20334 C GLY F 286 7863029616 7534 1009653 F ATOM 20419 C ASN F 297 77527 11241 10362 1006991 F

ATOM 20335 O GLY F 286 77835 30239 8242 1009653 F ATOM 20420 O ASN F 297 77231 10951 9199 1006991 F

ATOM 20336 N PHE F 287 7882928308 7664 1008386 F ATOM 20421 N THR F 298 77460 10383 11371 1006038 F

ATOM 20337 CA PHE F 287 7811727542 8685 1008386 F ATOM 20422 CA THR F 298 77047 9001 11198 1006038 F

ATOM 20338 CB PHE F 287 76833 26924 8106 1007892 F ATOM 20423 CB THR F 298 77163 8248 12543 1007301 F

ATOM 20339 CG PHE F 287 77075 25816 7100 1007892 F ATOM 20424 OGl THR F 298 76355 7072 12504 1007301 F

ATOM 20340 CDl PHEF287 7727624499 7516 1007892 F ATOM 20425 CG2 THR F 298 76715 9132 13697 1007301 F

ATOM 20341 CD2PHEF287 77113 26095 5733 1007892 F ATOM 20426 C THR F 298 75630 8847 10633 1006038 F

ATOM 20342 CEl PHE F 287 77513 23480 6587 1007892 F ATOM 20427 O THR F 298 75324 7852 9982 1006038 F ATOM 20343 CE2PHEF287 77351 25076 4796 1007892 F ATOM 20428 N LEU F 299 74773 9836 10861 1008119 F

ATOM 20344 CZ PHE F 287 77551 23771 5227 1007892 F ATOM 20429 CA LEU F 299 73397 9772 10367 1008119 F

ATOM 20345 C PHE F 287 79005 26449 9268 1008386 F ATOM 20430 CB LEU F 299 72443 10312 11429 1007046 F

ATOM 20346 O PHE F 287 79791 25821 8554 1008386 F ATOM 20431 CG LEU F 299 72380 9469 12702 1007046 F

ATOM 20347 N PRO F 288 7888926209 10583 1008499 F ATOM 20432 CDl LEU F 299 71523 10173 13739 1007046 F

ATOM 20348 CD PRO F 288 7794726853 11517 1007717 F ATOM 20433 CD2 LEU F 299 71816 8103 12376 1007046 F

ATOM 20349 CA PRO F 288 7968425187 11268 1008499 F ATOM 20434 C LEU F 299 73158 10516 9052 1008119 F

ATOM 20350 CB PRO F 288 7933825416 12738 1007717 F ATOM 20435 O LEU F 299 72016 10635 8594 1008119 F

ATOM 20351 CG PRO F 288 7791425871 12672 1007717 F ATOM 20436 N TRP F 300 74235 11006 8446 1006846 F

ATOM 20352 C PRO F 288 7935323772 10803 1008499 F ATOM 20437 CA TRP F 300 74141 11747 7196 1006846 F

ATOM 20353 O PRO F 288 7820023343 10861 1008499 F ATOM 20438 CB TRP F 300 75531 11977 6608 007770 F ATOM 20354 N LYSF289 8036723050 10336 1009914 F ATOM 20439 CG TRP F 300 75496 12763 5348 1007770 F

ATOM 20355 CA LYS F 289 8015921685 9875 1009914 F ATOM 20440 CD2 TRP F 300 74991 14091 5181 1007770 F

ATOM 20356 CB LYS F 289 8125521291 8880 10012338 F ATOM 20441 CE2TRPF300 75164 14435 3822 1007770 F

ATOM 20357 CG LYS F 289 8103721900 7499 10012338 F ATOM 20442 CE3 TRP F 300 74411 15027 6049 1007770 F

ATOM 20358 CD LYS F 289 8213021521 6520 10012338 F ATOM 20443 CDl TRP F 300 7594C 12363 4121 1007770 F

ATOM 20359 CE LYSF289 8344022211 6868 10012338 F ATOM 20444 NEl TRP F 300 75745 13362 3199 1007770 F

ATOM 20360 NZ LYSF289 8452921886 5897 10012338 F ATOM 20445 CZ2TRPF300 74776 15678 3306 1007770 F

ATOM 20361 C LYS F 289 8009420709 11048 1009914 F ATOM 20446 CZ3 TRP F 300 74025 16264 5537 1007770 F

ATOM 20362 O LYS F 289 81049 19990 11346 1009914 F ATOM 20447 CH2 TRP F 300 7421C 16577 4177 1007770 F

ATOM 20363 N VAL F 290 7893420696 11700 10010007 F ATOM 20448 C TRP F 300 73273 11035 6175 1 006846 F

ATOM 20364 CA VAL F 290 78679 19841 12850 10010007 F ATOM 20449 O TRP F 300 72467 11670 5499 1 006846 F

ATOM 20365 CB VAL F 290 7876220653 14152 1008808 ATOM 20450 N LYS F 301 73436 9719 6066 1 007036 F ATOM 20366 CGl VAL F 290 80063 21425 14191 1008808 F ATOM 20451 CA LYS F 301 72659 8948 5107 1 007036 F ATOM 20367 CG2 VALF290 7757821613 14247 1008808 F ATOM 20452 CB LYS F 301 73021 7461 5175 1 008596 F

ATOM 20368 C VAL F 290 77277 19243 12748 10010007 F ATOM 20453 CG LYS F 301 74493 7170 4875 1 008596 F

ATOM 20369 O VALF290 76473 19671 11921 10010007 F ATOM 20454 CD LYS F 301 74974 7869 3598 1 008596 F

ATOM 20370 N GLY F 291 76992 18263 13601 1008221 F ATOM 20455 CE LYS F 301 76497 7925 3532 1 008596 F

ATOM 20371 CA GLY F 291 75685 17623 13610 1008221 F ATOM 20456 NZ LYS F 301 76982 8940 2552 1 008596 F

ATOM 20372 C GLY F 291 75143 17183 12260 1008221 F ATOM 20457 C LYS F 301 71165 9136 5327 1007036 F

ATOM 20373 O GLY F 291 75838 16551 11462 1008221 F ATOM 20458 O LYS F 301 70392 9185 4366 1007036 F

ATOM 20374 N METF292 73884 17519 12005 1006527 F ATOM 20459 N ASP F 302 70750 9258 6583 1006824 F

ATOM 20375 CA MET F 292 73221 17171 10754 1006527 F ATOM 20460 CA ASP F 302 69335 9459 6869 1006824 F

ATOM 20376 CB MET F 292 71740 17481 10861 1008153 F ATOM 20461 CB ASP F 302 69043 9185 8340 10012237 F

ATOM 20377 CG METF292 71501 18972 10915 1008153 F ATOM 20462 CG ASP F 302 69119 7713 8675 10012237 F

ATOM 20378 SD MET F 292 69833 19430 10526 1008153 F ATOM 20463 ODl ASP F 302 68479 6914 7959 10012237 F

ATOM 20379 CE METF292 69283 20070 12103 1008153 F ATOM 20464 OD2 ASP F 302 69811 7354 9651 10012237 F

ATOM 20380 C MET F 292 73766 17950 9558 1006527 F ATOM 20465 C ASP F 302 68907 10876 6496 1006824 F

ATOM 20381 O MET F 292 73307 17759 8441 1006527 F ATOM 20466 O ASP F 302 67788 11096 6022 1006824 F

ATOM 20382 N LEU F 293 74733 18827 9788 1008908 F ATOM 20467 N VAL F 303 69799 11836 6711 1006720 F

ATOM 20383 CA LEU F 293 75273 19639 8708 1008908 F ATOM 20468 CA VAL F 303 69500 13216 6360 1006720 F

ATOM 20384 CB LEU F 293 7553021058 9220 1008122 F ATOM 20469 CB VAL F 303 70676 14148 6711 1006700 F

ATOM 20385 CG LEU F 293 74285 21834 9660 1008122 F ATOM 20470 CGl VAL F 303 70402 15556 6202 1005631 F

ATOM 20386 CDl LEU F 293 7468623170 10285 1008122 F ATOM 20471 CG2VALF3O3 70881 14165 8218 1005631 F

ATOM 20387 CD2 LEU F 293 7338222041 8455 1008122 F ATOM 20472 C VAL F 303 69232 13279 4859 1006720 F ATOM 20388 C LEUF293 76518 19131 7987 1008908 F ATOM 20473 O VAL F 303 68198 13797 4433 1006720 F

ATOM 20389 O LEU F 293 76957 19759 7026 1008908 ATOM 20474 N LYS F 304 70166 12746 4067 1006852 F

ATOM 20390 N THR F 294 77096 18013 8428 1007168 F ATOM 20475 CA LYS F 304 70036 12727 2611 1006852 F

ATOM 20391 CA THR F 294 78293 17487 7760 1007168 F ATOM 20476 CB LYS F 304 71134 11873 1977 10011359 F

ATOM 20392 CB THRF294 79549 17520 8639 10011261 F ATOM 20477 CG LYS F 304 72454 12566 1742 1009551 F ATOM 20393 OG1THRF294 79574 18727 9404 10011261 F ATOM 20478 CD LYS F 304 73438 11580 1125 1009551 F ATOM 20394 CG2 THR F 294 80797 17462 7756 10011261 F ATOM 20479 CE LYS F 304 74759 12250 0762 1009551 F

ATOM 20395 C THR F 294 78142 16049 7332 1007168 F ATOM 20480 NZ LYS F 304 75794 11274 0301 1009551 F

ATOM 20396 O THR F 294 77430 15265 7955 1007168 F ATOM 20481 C LYS F 304 68689 12145 2212 1006852 F

ATOM 20397 N VAL F 295 78843 15702 6266 1006288 F ATOM 20482 O LYS F 304 67979 12693 1367 1006852 F

ATOM 20398 CA VAL F 295 78798 14350 5755 1006288 F ATOM 20483 N ALA F 305 68334 11031 2835 1004830 F ATOM 20399 CB VAL F 295 79518 14258 4400 1008454 F ATOM 20484 CA ALA F 305 67074 10366 2519 1004830 F

ATOM 20400 CGl VALF 295 79394 12848 3835 1008454 F ATOM 20485 CB ALA F 305 67061 8982 3100 100 184 F ATOM 20401 CG2VALF295 78931 15284 3442 1008454 F ATOM 20486 C ALA F 305 65821 11099 2956 1004830 F

ATOM 20402 C VAL F 295 79497 13461 6766 1006288 F ATOM 20487 O ALA F 305 64908 11285 2166 1004830 F

ATOM 20403 O VAL F 295 79293 12249 6793 1006288 F ATOM 20488 N TYR F 306 65764 11505 4218 1005626 F

ATOM 20404 N LYS F 296 80323 14084 7602 1006666 F ATOM 20489 CA TYR F 306 64588 12206 4723 1005626 F

ATOM 20405 CA LYS F 296 81081 13376 8638 1006666 F ATOM 20490 CB TYR F 306 64621 12248 6245 1007860 F

ATOM 20406 CB LYS F 296 81939 14371 9430 10010987 F ATOM 20491 CG TYR F 306 64486 10893 6879 1007329 F 65251/C766

ATOM 20492 CDl TYR F 306 65063 10622 8119 1007329 F ATOM 20577 CD2LEUF317 54476 12874 -7167 1005146 F ATOM 20493 CEl TYR F 306 64929 9383 8717 1007329 F ATOM 20578 C LEU F 317 52858 14774 -3634 1006008 F

ATOM 20494 CD2 TYR F 306 63768 9885 6250 1007329 F ATOM 20579 O LEU F 317 51650 14690 -3876 1006008 F

ATOM 20495 CE2TYRF306 63626 8642 6837 1007329 F ATOM 20580 N ALA F 318 53339 14958 -2411 1006198 F

ATOM 20496 CZ TYR F 306 64208 8397 8071 1007329 F ATOM 20581 CA ALA F 318 52466 15047 -1257 1006198 F

ATOM 20497 OH TYR F 306 64054 7165 8663 1007329 F ATOM 20582 CB ALA F 318 53307 15125 0008 1007004 F

ATOM 20498 C TYR F 306 64438 13619 4183 1005626 F ATOM 20583 C ALAF318 51523 16245 -1334 1006198 F

ATOM 20499 O TYR F 306 63380 13976 3690 1005626 F ATOM 20584 O ALA F 318 50319 16109 1 111 1006198 F

ATOM 20500 N LEU F 307 65493 14418 4277 1006269 F ATOM 20585 N ILE F 319 52066 17416 -1654 1007043 F

ATOM 20501 CA LEU F 307 65439 15794 3809 1006269 F ATOM 20586 CA ILEF319 51252 18619 -1711 1007043 F ATOM 20502 CB LEUF307 66509 16631 4511 1007281 F ATOM 20587 CB ILEF319 52027 19805 -2321 1007692 F

ATOM 20503 CG LEU F 307 66684 18054 3986 1004094 F ATOM 20588 CG2ILEF319 52222 19592 -3806 1005148 F

ATOM 20504 CD1 LEUF307 65379 18836 4133 1004094 F ATOM 20589 CGl ILE F 319 51246 21 105 -2085 1005148 F

ATOM 20505 CD2LEUF307 67811 18738 4740 1004094 F ATOM 20590 CDl ILEF319 51993 22380 -2490 1005148 F

ATOM 20506 C LEU F 307 65622 15879 2301 1006269 F ATOM 20591 C ILE F 319 49961 18405 -2491 I 007043 F

ATOM 20507 O LEU F 307 64807 16483 1597 1006269 F ATOM 20592 O ILE F 319 48948 19025 -2188 1007043 F

ATOM 20508 N GLY F 308 66692 15270 1806 1005727 F ATOM 20593 N LEU F 320 49988 17521 -3482 1009003 F

ATOM 20509 CA GLY F 308 66946 15303 0381 1005727 F ATOM 20594 CA LEU F 320 48794 17258 -4276 1009003 F

ATOM 20510 C GLYF308 65799 14711 -0422 1005727 F ATOM 20595 CB LEU F 320 49166 16507 -5556 1009215 F

ATOM 20511 O GLY F 308 65342 15310 -1393 1005727 F ATOM 20596 CG LEU F 320 50050 17298 -6533 1006999 F

ATOM 20512 N GLY F 309 65327 13538 -0014 1005654 F ATOM 20597 CDl LEU F 320 50317 16452 -7776 1006999 F ATOM 20513 CA GLY F 309 64245 12889 -0730 1005654 F ATOM 20598 CD2 LEU F 320 49376 18619 -6917 1006999 F

ATOM 20514 C GLY F 309 62988 13727 -0806 1005654 F ATOM 20599 C LEU F 320 47728 16490 -3491 1009003 F

ATOM 20515 O GLYF309 62409 13909 -1877 1005654 F ATOM 20600 O LEU F 320 46532 16664 3732 1009003 F

ATOM 20516 N PHEF310 62565 14244 0339 1005421 F ATOM 20601 N ASP F 321 48154 15642 -2557 1007618 F

ATOM 20517 CA PHE F 310 61364 15058 0416 1005421 F ATOM 20602 CA ASP F 321 47202 14896 -1 737 1007618 F

ATOM 20518 CB PHE F 310 61 172 15530 1857 1005782 F ATOM 20603 CB ASP F 321 47905 13777 0962 10016250 F

ATOM 20519 CG PHE F 310 59844 16171 2119 1005365 F ATOM 20604 CG ASP F 321 48356 12639 -1858 10014150 F

ATOM 20520 CDl PHE F 310 58673 15445 1966 1005365 F ATOM 20605 ODl ASP F 321 47557 12223 -2725 10014150 F

ATOM 20521 CD2PHEF310 59766 17502 2529 1005365 F ATOM 20606 OD2ASPF321 49498 12152 -1686 10014150 F

ATOM 20522 CEl PHE F 310 57433 16031 2218 1005365 F ATOM 20607 C ASP F 321 46521 15858 -0754 1007618 F

ATOM 20523 CE2PHEF310 58532 18098 2785 1005365 F ATOM 20608 O ASP F 321 45326 15737 -0480 1007618 F

ATOM 20524 CZ PHE F 310 57361 17357 2627 1005365 F ATOM 20609 N TYR F 322 47282 16814 -0225 1009402 F

ATOM 20525 C PHE F 310 61493 16263 -0513 1005421 F ATOM 20610 CA TYR F 322 46725 17787 0712 1009402 F

ATOM 20526 O PHE F 310 60559 16602 -1252 1005421 ATOM 20611 CB TYR F 322 47797 18759 1219 1008706 F

ATOM 20527 N GLU F 311 62661 16899 -0466 1005562 F ATOM 20612 CG TYR F 322 48749 18195 2256 1007777 F

ATOM 20528 CA GLU F 311 62928 18070 -1279 1005562 F ATOM 20613 CDl TYR F 322 49705 17242 1911 1007777 F

ATOM 20529 CB GLU F 311 64205 18756 -0806 1007914 F ATOM 20614 CEl TYR F 322 50613 16756 2854 1007777 F

ATOM 20530 CG GLU F 311 64261 20211 1192 1006337 F ATOM 20615 CD2 TYR F 322 48718 18645 3575 1007777 F

ATOM 20531 CD GLU F 311 6560420848 -0909 1006337 F ATOM 20616 CE2 TYR F 322 49619 18164 4523 1007777 F

ATOM 20532 OE1GLUF311 6620520524 0125 1006337 F ATOM 20617 CZ TYR F 322 50564 17223 4154 1007777 F

ATOM 20533 OE2 GLU F 311 6605621691 1710 1006337 F ATOM 20618 OH TYR F 322 51476 16758 5071 1007777 F

ATOM 20534 C GLUF311 63064 17712 -2756 1005562 ATOM 20619 C TYR F 322 45650 18581 -0002 1009402 F

ATOM 20535 O GLU F 311 62693 18497 -3624 1005562 F ATOM 20620 O TYR F 322 44546 18766 0511 1009402 F

ATOM 20536 N TYR F 312 63593 16526 -3041 1006790 F ATOM 20621 N GLN F 323 45987 19051 -1 195 10010793 F

ATOM 20537 CA TYR F 312 63775 16105 -4423 1006790 F ATOM 20622 CA GLN F 323 45058 19827 -1990 10010793 F

ATOM 20538 CB TYR F 312 64671 14878 -4508 1006043 F ATOM 20623 CB GLN F 323 45664 20128 -3353 10010455 F

ATOM 20539 CG TYR F 312 64950 14462 -5930 1005513 F ATOM 20624 CG GLN F 323 44749 20934 -4230 1007894 F

ATOM 20540 CDl TYR F 312 65818 15204 -6731 1005513 F ATOM 20625 CD GLN F 323 45395 21317 -5531 1007894 F

ATOM 20541 CE1TYRF312 66052 14855 -8052 1005513 F ATOM 20626 OEl GLN F 323 45927 20467 -6243 1007894 F

ATOM 20542 CD2TYRF312 64314 13350 -6489 1005513 F ATOM 20627 NE2 GLN F 323 45351 22605 -5858 1007894 F

ATOM 20543 CE2TYRF312 64537 12987 -7816 1005513 F ATOM 20628 C GLN F 323 43726 19104 -2160 10010793 F

ATOM 20544 CZ TYR F 312 65409 13746 -8594 1005513 F ATOM 20629 O GLN F 323 42672 19708 -1986 10010793 F

ATOM 20545 OH TYR F 312 65642 13408 -9916 1005513 F ATOM 20630 N LYS F 324 43771 17816 -2498 1008347 F

ATOM 20546 C TYR F 312 62480 15791 -5142 1006790 F ATOM 20631 CA LYS F 324 42551 17029 -2672 1008347 F

ATOM 20547 O TYR F 312 62347 16072 -6331 1006790 F ATOM 20632 CB LYS F 324 42875 15576 -3007 1008553 F

ATOM 20548 N METF313 61523 15202 -4439 1005484 F ATOM 20633 CG LYS F 324 43281 15323 -4428 1007496 F

ATOM 20549 CA MET F 313 60274 14866 -5093 1005484 F ATOM 20634 CD LYS F 324 43296 13825 -4697 1007496 F

ATOM 20550 CB MET F 313 60483 13656 -6001 1008195 F ATOM 20635 CE LYS F 324 43676 13514 -6145 1007496 F

ATOM 20551 CG MET F 313 59248 13264 -6774 1008180 F ATOM 20636 NZ LYS F 324 43539 12066 -6484 1007496 F

ATOM 20552 SD METF313 59501 11779 7722 1008180 F ATOM 20637 C LYS F 324 41679 17032 -1426 I 008347 F

ATOM 20553 CE MET F 313 60905 12266 -8725 1008180 F ATOM 20638 O LYS F 324 40485 17305 -1497 1008347 F

ATOM 20554 C MET F 313 59129 14579 -4137 1005484 F ATOM 20639 N MET F 325 42274 16708 -0286 1008699 F

ATOM 20555 O MET F 313 57970 14873 -4437 1005484 F ATOM 20640 CA MET F 325 41528 16661 0958 1008699 F

ATOM 20556 N GLY F 314 59453 13997 -2990 1005056 F ATOM 20641 CB MET F 325 42315 15887 2005 10010364 F

ATOM 20557 CA GLY F 314 58429 13658 -2025 1005056 F ATOM 20642 CG MET F 325 42513 14441 1639 1009220 F ATOM 20558 C GLY F 314 57408 14750 -1776 1005056 F ATOM 20643 SD MET F 325 43448 13539 2881 1009220 F

ATOM 20559 O GLY F 314 56199 14530 -1883 1005056 F ATOM 20644 CE MET F 325 45075 13620 2194 1009220 F

ATOM 20560 N CYS F 315 57893 15939 -1447 1006824 F ATOM 20645 C MET F 325 41 162 18028 1510 1008699 F

ATOM 20561 CA CYS F 315 57005 17047 -1163 1006824 ATOM 20646 O MET F 325 40324 18130 2401 1008699 F

ATOM 20562 CB CYSF315 57822 18271 -0774 1007700 F ATOM 20647 N ALA F 326 41777 19079 0989 1009207 F

ATOM 20563 SG CYS F 315 56825 19549 -0022 1008237 F ATOM 20648 CA ALA F 326 41470 20411 1482 1009207 F

ATOM 20564 C CYS F 315 56073 17389 -2326 1006824 F ATOM 20649 CB ALA F 326 42741 21267 1504 1005053 F

ATOM 20565 O CYS F 315 54855 17466 -2150 1006824 F ATOM 20650 C ALA F 326 40386 21098 0651 1009207 F

ATOM 20566 N SER F 316 56639 17585 -3514 1005361 F ATOM 20651 O ALA F 326 39670 21967 1 154 1009207 F

ATOM 20567 CA SER F 316 55836 17937 -4680 1005361 F ATOM 20652 N LYS F 327 40259 20687 -0608 10014374 F

ATOM 20568 CB SER F 316 56716 18071 5920 1005417 F ATOM 20653 CA LYS F 327 39301 21278 -1538 10014374 F ATOM 20569 OG SERF316 57224 16813 -6304 1005967 F ATOM 20654 CB LYS F 327 38732 20220 2484 10017339 F

ATOM 20570 C SERF316 54727 16933 -4955 1005361 F ATOM 20655 CG LYS F 327 37983 20844 -3649 1009168 F

ATOM 20571 O SER F 316 53710 17276 -5552 1005361 F ATOM 20656 CD LYS F 327 37542 19819 -4672 1009168 F

ATOM 20572 N LEU F 317 54921 15690 -4539 1006008 F ATOM 20657 CE LYS F 327 36893 20491 -5880 1009168 F

ATOM 20573 CA LEU F 317 53896 14679 -4746 1006008 F ATOM 20658 NZ LYS F 327 36409 19495 -6882 1009168 F

ATOM 20574 CB LEU F 317 54516 13286 -4745 1005895 F ATOM 20659 C LYS F 327 38149 22053 -0916 10014374 F

ATOM 20575 CG LEU F 317 55366 12931 -5960 1005146 F ATOM 20660 O LYS F 327 38072 23271 -1057 10014374 F

ATOM 20576 CDl LEU F 317 56063 11592 -5757 1005146 F ATOM 20661 N GLY F 328 37255 21364 -0222 1009023 F 65251/C766

ATOM 20662 CA GLY F 328 3612922070 0359 1009023 F ATOM 20747 NZ LYS F 339 4258249136 -6872 10013562 F ATOM 20663 C GLY F 328 36293 22692 1735 1009023 F ATOM 20748 C LYS F 339 4944648553 -9580 1008420 F ATOM 20664 O GLY F 328 3559923655 2051 1009023 F ATOM 20749 O LYS F 339 4997748266 -8509 1007686 F ATOM 20665 N LYS F 329 3721322181 2546 1009568 F ATOM 20750 N VALF340 50112 49097-10585 1009291 F ATOM 20666 CA LYS F 329 37368 22691 3902 1009568 F ATOM 20751 CA VAL F 340 51523 49422 10447 1009034 F ATOM 20667 CB LYS F 329 37741 21535 4833 10017553 F ATOM 20752 CB VAL F 340 52342 48918 -11643 1009764 F ATOM 20668 CG LYS F 329 36653 20484 4958 10017553 F ATOM 20753 CGl VAL F 340 5380249313-11470 1008310 F ATOM 20669 CD LYS F 329 36876 19633 6191 10017553 F ATOM 20754 CG2 VAL F 340 52205 47417-11771 1008310 F ATOM 20670 CE LYS F 329 35766 18620 6397 1006529 F ATOM 20755 C VALF340 51653 50933-10402 1009291 F ATOM 20671 NZ LYS F 329 35991 17818 7645 1006529 F ATOM 20756 0 VALF340 51208 51607-11316 1008976 F ATOM 20672 C LYS F 329 3826423893 4218 1009568 F ATOM 20757 N THRF341 52267 51473 -9355 10010737 F ATOM 20673 O LYS F 329 3860524102 5382 1009568 F ATOM 20758 CA THR F 341 52411 52919 -9255 10010327 F ATOM 20674 N ILE F 330 3865024690 3225 10010900 F ATOM 20759 CB THR F 341 51878 53427 -7914 10010656 F ATOM 20675 CA ILE F 330 3947725868 3519 10010900 F ATOM 20760 OGl THR F 341 50495 53076 -7801 1008792 F ATOM 20676 CB ILE F 330 4099625611 3271 10010763 F ATOM 20761 CG2THRF341 52027 54945 -7818 1008792 F ATOM 20677 CG2 ILE F 330 41461 24394 4061 10010855 F ATOM 20762 C THR F 341 53849 53383 -9420 10010542 F ATOM 20678 CGl ILE F 330 4126925429 1780 10010855 F ATOM 20763 O THR F 341 54784 52709 -8995 10010702 F ATOM 20679 CDl ILE F 330 4272925549 1425 10010855 F ATOM 20764 N GLYF342 54014 54545-10041 10013851 F ATOM 20680 C ILE F 330 39036 27062 2675 10010900 F ATOM 20765 CA GLY F 342 55343 55081 -10252 10014268 F ATOM 20681 O ILE F 330 3822726912 1760 10010900 F ATOM 20766 C GLY F 342 5564456286 -9383 10014165 F ATOM 20682 N PRO F 331 3955928267 2974 10011313 F ATOM 20767 O GLY F 342 5583657386 -9896 10013592 F ATOM 20683 CD PRO F 331 40553 28596 4013 1006398 F ATOM 20768 N ASN F 343 55682 56084 -8068 10013948 F ATOM 20684 CA PRO F 331 3919029467 2215 10011313 F ATOM 20769 CA ASN F 343 55983 57167 -7134 10014589 F ATOM 20685 CB PRO F 331 40243 30482 2644 10020084 F ATOM 20770 CB ASN F 343 55769 56705 -5690 10017365 F ATOM 20686 CG PRO F 331 40487 30115 4051 1006398 F ATOM 20771 CG ASN F 343 54399 56100 -5465 10015345 F ATOM 20687 C PROF331 3921729224 0712 10011313 F ATOM 20772 ODl ASN F 343 53376 56767 -5628 10015345 F ATOM 20688 O PRO F 331 4014428606 0198 I 0011313 F ATOM 20773 ND2 ASN F 343 54372 54825 -5086 10015345 F ATOM 20689 N LYS F 332 38193 29705 0015 1009459 F ATOM 20774 C ASN F 343 57447 57548 -7323 10014395 F ATOM 20690 CA LYS F 332 38111 29545 -1431 1009521 F ATOM 20775 O ASNF343 58073 57157 -8309 10013258 F ATOM 20691 CB LYS F 332 3671429921 -1922 10014540 F ATOM 20776 N GLU F 344 57992 58308 -6379 10015616 F ATOM 20692 CG LYS F 332 3634831356 -1610 10011694 F ATOM 20777 CA GLU F 344 59392 58717 -6440 10015616 F ATOM 20693 CD LYS F 332 3522031851 -2488 10011694 F ATOM 20778 CB GLU F 344 59581 59817 -7488 10015985 F ATOM 20694 CE LYS F 332 3502033351 -2317 10011694 F ATOM 20779 CG GLU F 344 59858 59250 -8875 10013975 F ATOM 20695 NZ LYS F 332 3400633882 -3264 10011694 F ATOM 20780 CD GLU F 344 59879 60300 -9964 10013975 F ATOM 20696 C LYS F 332 3914030453 -2104 1009428 F ATOM 20781 OEl GLU F 344 58797 60793-10343 10013975 F ATOM 20697 O LYS F 332 3959531442 1519 1009237 F ATOM 20782 OE2 GLU F 344 60981 60637-10442 10013975 F ATOM 20698 N ASP F 333 39513 30114 -3332 1009944 F ATOM 20783 C GLU F 344 59903 59158 -5073 10015616 F ATOM 20699 CA ASP F 333 40473 30922 -4072 1009890 F ATOM 20784 O GLUF344 59534 60215 -4562 10015616 F ATOM 20700 CB ASP F 333 4079630264 -5411 10018051 F ATOM 20785 N LEU F 345 60763 58320 4496 10020084 F ATOM 20701 CG ASP F 333 4196429314 -5319 10014810 F ATOM 20786 CA LEU F 345 61330 58537 -3166 10020084 F ATOM 20702 ODl ASP F 333 4209028627 -4286 10014810 F ATOM 20787 CB LEU F 345 61921 57216 -2640 10020084 F ATOM 20703 OD2 ASP F 333 42753 29249 -6285 10014810 F ATOM 20788 CG LEU F 345 60964 56022 -2470 10015535 F ATOM 20704 C ASP F 333 39880 32298 -4312 10010275 F ATOM 20789 CDl LEU F 345 61717 54833 1886 10015535 F ATOM 20705 O ASP F 333 38683 32432 -4564 10010240 F ATOM 20790 CD2 LEU F 345 59805 56405 -1559 10015535 F ATOM 20706 N THR F 334 4071633324 -4226 1008713 F ATOM 20791 C LEU F 345 62353 59670 -2996 10020084 F ATOM 20707 CA THR F 334 40254 34687 -4443 1008685 F ATOM 20792 O LEU F 345 63283 59560 -2196 10020084 F ATOM 20708 CB THR F 334 4002735412 -3102 10010813 F ATOM 20793 N GLU F 346 6217760750 -3753 10016895 F ATOM 20709 OGl THR F 334 38830 34909 -2495 1009403 F ATOM 20794 CA GLU F 346 63029 61941 -3666 10016895 F ATOM 20710 CG2 THR F 334 3990636922 -3311 1009403 F ATOM 20795 CB GLU F 346 62896 62536 -2262 10018872 F ATOM 20711 C THR F 334 41252 35463 -5282 1009329 F ATOM 20796 CG GLU F 346 61453 62539 -1771 10017415 F ATOM 20712 O THR F 334 4241435623 -4901 1009065 F ATOM 20797 CD GLU F 346 61207 63511 -0638 10017415 F ATOM 20713 N THR F 335 4078435947 -6427 1006999 F ATOM 20798 OEl GLU F 346 61312 64733 -0876 10017415 F ATOM 20714 CA THR F 335 4163336696 -7338 1006978 F ATOM 20799 OE2 GLU F 346 60907 63056 0486 10017415 F ATOM 20715 CB THR F 335 4102236749 -8727 1007088 F ATOM 20800 C GLU F 346 64512 61864 -4055 10016895 F ATOM 20716 OGl THR F 335 40561 35439 9093 1006024 F ATOM 20801 O GLU F 346 64898 62369 -5109 10016895 F ATOM 20717 CG2 THR F 335 4206737222 -9728 1006024 F ATOM 20802 N ASPF347 6534761257 -3213 10018728 F ATOM 20718 C THR F 335 4189938115 -6869 1007064 F ATOM 20803 CA ASPF347 6677761172 -3515 10018728 F ATOM 20719 O THR F 335 40985 38830 -6476 1007199 F ATOM 20804 CB ASP F 347 67543 60531 -2348 10020084 F ATOM 20720 N PRO F 336 43165 38547 -6928 1008430 F ATOM 20805 CG ASP F 347 67496 59013 -2373 10020084 F ATOM 20721 CD PRO F 336 4436437799 -7341 1006490 F ATOM 20806 ODl ASP F 347 66387 58446 -2278 10020084 F ATOM 20722 CA PRO F 336 4353639889 -6495 1008388 F ATOM 20807 OD2 ASP F 347 68574 58387 -2488 10020084 F ATOM 20723 CB PRO F 336 4500739729 -6169 1007376 F ATOM 20808 C ASP F 347 67062 60400 4803 10018728 F ATOM 20724 CG PRO F 336 45455 38866 -7287 1006490 F ATOM 20809 O ASP F 347 67969 60755 -5558 10018728 F ATOM 20725 C PRO F 336 4331940972 -7531 1008392 F ATOM 20810 N GLY F 348 66288 59346 -5049 10014880 F ATOM 20726 O PRO F 336 42973 40703 -8680 1008455 F ATOM 20811 CA GLY F 348 66473 58549 -6249 10014611 F ATOM 20727 N THR F 337 4354342202 -7086 1007946 F ATOM 20812 C GLY F 348 65490 58950 -7329 10014307 F ATOM 20728 CA THR F 337 4343643394 -7904 1008292 F ATOM 20813 O GLY F 348 64374 59372 -7029 10013808 F ATOM 20729 CB THR F 337 42545 44444 -7225 10012418 F ATOM 20814 N ASN F 349 65894 58817 -8588 10020077 F ATOM 20730 OGl THR F 337 4118044017 -7279 1007507 F ATOM 20815 CA ASN F 349 65026 59189 -9695 10020067 F ATOM 20731 CG2 THR F 337 4269645798 -7901 1007507 F ATOM 20816 CB ASN F 349 6566458785-11033 10020084 F ATOM 20732 C THR F 337 44861 43910 -7942 1009049 F ATOM 20817 CG ASN F 349 66437 57485-10948 10018818 F ATOM 20733 O THR F 337 4551943997 -6902 1008187 F ATOM 20818 ODl ASN F 349 67418 57376-10209 10018818 ATOM 20734 N VAL F 338 45355 44242 -9125 1008398 F F ATOM 20735 CA VAL F 338 4672244729 -9215 1009084 F ATOM 20819 ND2ASNF349 66003 56492-11714 10018818 ATOM 20736 CB VAL F 338 4760843782 -10064 1009216 F F ATOM 20737 CGl VAL F 338 4907644187 -9938 1009178 F ATOM 20820 C ASN F 349 63597 58646 •9592 10020077 F ATOM 20738 CG2 VAL F 338 4741042343 -9617 1009178 F ATOM 20821 O ASN F 349 62709 59348 ■9111 10020077 F ATOM 20739 C VAL F 338 46782 46122 -9810 1009531 F ATOM 20822 N MET F 350 63371 57406-10019 10014067 F ATOM 20740 O VAL F 338 45963 46483-10651 1009514 F ATOM 20823 CA MET F 350 62025 56832 -9981 10013676 F ATOM 20741 N LYS F 339 47761 46896 -9353 1007733 F ATOM 20824 CB MET F 350 61550 56562 -11411 10020084 F ATOM 20742 CA LYS F 339 4798048260 -9814 1007521 F ATOM 20825 CG MET F 350 60166 55954 11506 10016028 F ATOM 20743 CB LYS F 339 4711849233 -9008 10016731 F ATOM 20826 SD MET F 350 59607 55782 -13203 10016028 F ATOM 20744 CG LYS F 339 45623 49037 -9212 10013562 F ATOM 20827 CE MET F 350 58490 57199 -13330 10016028 F ATOM 20745 CD LYS F 339 4482449379 -7962 10013562 F ATOM 20828 C MET F 350 6187655559 -9144 10013390 F ATOM 20746 CE LYS F 339 4335449018 -8141 10013562 F ATOM 20829 O MET F 350 62846 54834 -8916 10013033 F 65251/C766

ATOM 20830 N THR F 351 60 650 55 299 8 688 1 00128 39 F ATOM 20915 CG PRO F 361 45622 31151 -3673 1007687 F ATOM 20831 CA THR F 351 60348 54 113 -7 886 1 00126 35 F ATOM 20916 C PRO F 361 4719832460 -1169 1007676 F

ATOM 20832 CB THR F 351 60202 54460 -6 374 1 00133 23 F ATOM 20917 O PRO F 361 4756033174 -2097 1007393 F ATOM 20833 OGl THR F 351 60 658 53 358 -5 583 1 0010035 F ATOM 20918 N PRO F 362 4766432622 0078 1006255 F ATOM 20834 CG2 THR F 351 58 744 54722 -6 005 1 00100 35 F ATOM 20919 CD PRO F 362 47333 31706 1183 1006912 F

ATOM 20835 C THR F 351 59 047 53 465 -8 369 I 00120 58 F ATOM 20920 CA PRO F 362 48668 33609 0498 1005626 F

ATOM 20836 O THR F 351 58 054 54 154 -8 621 1 00112 17 F ATOM 20921 CB PRO F 362 48804 33351 1992 1006912 F

ATOM 20837 N LEU F 352 59 058 52 143 -8 508 1 00 94 95 F ATOM 20922 CG PRO F 362 4849431897 2108 1006912 F

ATOM 20838 CA LEU F 352 57 871 51 424 -8 950 1 009797 ATOM 20923 C PRO F 362 5000633658 -0208 1005886 F

ATOM 20839 CB LEU F 352 58 196 50 555 -10 165 1 00141 26 F ATOM 20924 O PRO F 362 5074734643 -0068 1006362 F ATOM 20840 CG LEU F 352 58 233 51 374 -11 459 1 00122 32 F ATOM 20925 N ASP F 363 5032432608 -0963 1006073 F

ATOM 20841 CDl LEU F 352 58 825 50 563 -12 596 1 00122 32 F ATOM 20926 CA ASP F 363 51580 32580 -1701 1006058 F ATOM 20842 CD2 LEU F 352 56 819 51 827 -11 789 1 0012232 F ATOM 20927 CB ASP F 363 52001 31134 -2032 1008803 F

ATOM 20843 C LEU F 352 57 304 50 582 -7 822 1 00 94 65 F ATOM 20928 CG ASP F 363 5086730291 -2607 1008224 F

ATOM 20844 O LEU F 352 58 041 49918 -7 092 1 00 90 27 F ATOM 20929 ODl ASP F 363 49818 30152 -1934 1008224 F

ATOM 20845 N GLU F 353 55 984 50 625 -7 684 1 00 84 15 F ATOM 20930 OD2 ASP F 363 5103729751 -3729 1008224 F ATOM 20846 CA GLU F 353 55 306 49 890 -6 635 1 00 8040 F ATOM 20931 C ASP F 363 51460 33408 -2970 1006412 F

ATOM 20847 CB GLU F 353 54 767 50 861 -5 595 1 00200 84 F ATOM 20932 O ASP F 363 50565 33204 -3784 1006062 F ATOM 20848 CG GLU F 353 54069 50 189 -4443 1 00163 89 F ATOM 20933 N VAL F 364 52351 34376 -3109 1005371 F ATOM 20849 CD GLU F 353 53 480 51 190 3 482 1 00163 89 F ATOM 20934 CA VAL F 364 5236635233 -4285 1005603 F ATOM 20850 OEl GLU F 353 54 241 52043 -2 976 1 00163 80 F ATOM 20935 CB VAL F 364 51609 36567 -4057 1007246 F ATOM 20851 OE2 GLU F 353 52 259 51 124 -3 234 1 00163 89 F ATOM 20936 CGl VAL F 364 52062 37600 -5057 1005085 F

ATOM 20852 C GLU F 353 54 166 49 053 -7 178 1 00 83 65 F ATOM 20937 CG2 VAL F 364 50130 36357 -4245 1005085 F

ATOM 20853 O GLU F 353 53 177 49 581 -7 684 1 00 84 43 F ATOM 20938 C VAL F 364 53808 35551 -4584 1006337 F

ATOM 20854 N CYS F 354 54 316 47 740 -7 061 1 00 92 98 F ATOM 20939 O VAL F 364 54613 35750 -3677 1005511 F

ATOM 20855 CA CYS F 354 53 313 46 795 -7527 1 0093 26 F ATOM 20940 N ILE F 365 5414435572 -5860 1006991 F

ATOM 20856 C CYS F 354 52 513 46394 -6 305 1 00 9435 F ATOM 20941 CA ILE F 365 55494 35898 -6246 1006396 F

ATOM 20857 O CYS F 354 53 081 45 906 -5 328 1 00 93 05 ATOM 20942 CB ILE F 365 56271 34664 -6714 1007032 F

ATOM 20858 CB CYS F 354 54 001 45 562 -8 116 1 00148 13 F ATOM 20943 CG2 ILE F 365 5762735085 -7265 1004676 F

ATOM 20859 SG CYS F 354 52 961 44456 -9 125 1 0012532 F ATOM 20944 CGl ILE F 365 56461 33715 -5527 1004676 F

ATOM 20860 N THR F 355 51 206 46616 -6 333 1 00 7221 F ATOM 20945 CDl ILE F 365 57273 32475 -5827 1004676 F

ATOM 20861 CA THR F 355 50398 46 230 -5 184 1 00 61 57 F ATOM 20946 C ILE F 365 55429 36942 -7333 1007072 F ATOM 20862 CB THR F 355 49 752 47444 -4487 1 0014693 F ATOM 20947 O ILE F 365 54521 36954 -8169 1007149 F

ATOM 20863 OGl THR F 355 48 384 47 557 -4 896 1 00 96 08 F ATOM 20948 N THR F 366 5640937826 -7309 1005479 F ATOM 20864 CG2 THR F 355 50 497 48 722 -4 840 1 00 9608 F ATOM 20949 CA THR F 366 56462 38923 -8241 1006307 F

ATOM 20865 C THR F 355 49304 45270 -5 616 1 00 7506 F ATOM 20950 CB THR F 366 5622240225 -7468 10011243 F

ATOM 20866 O THR F 355 48 537 45 541 -6 547 I 00 67 86 F ATOM 20951 OGl THR F 366 55093 40901 -8024 10010011 F

ATOM 20867 N VAL F 356 49 250 44 138 -4 926 1 00 88 62 F ATOM 20952 CG2 THR F 366 57453 41121 -7500 10010011 F ATOM 20868 CA VAL F 356 48 278 43 093 5 206 1 00 84 34 F ATOM 20953 C THR F 366 57783 38997 -8985 1007205 F

ATOM 20869 CB VAL F 356 48 994 41 739 -5 345 1 00 80 43 F ATOM 20954 O THR F 366 58853 38839 -8391 1007129 F ATOM 20870 CGl VAL F 356 48 038 40 685 -5 871 1 00 6496 F ATOM 20955 N LYS F 367 57698 39239-10289 1007508 F ATOM 20871 CG2 VAL F 356 50 194 41 901 6 276 1 00 6496 F ATOM 20956 CA LYS F 367 58888 39360-11121 1007828 F

ATOM 20872 C VAL F 356 47295 43 070 -4 047 1 00 93 18 F ATOM 20957 CB LYS F 367 5897638216-12135 1009617 F

ATOM 20873 O VAL F 356 47 679 42 853 -2 896 1 00 9429 F ATOM 20958 CG LYS F 367 59354 36886-11530 1008718 F

ATOM 20874 N ASN F 357 46022 43 294 -4 360 1 00 82 80 F ATOM 20959 CD LYS F 367 5970435864-12591 1008718 F

ATOM 20875 CA ASN F 357 44995 43 362 -3 330 1 0079 02 ATOM 20960 CE LYS F 367 60269 34614 11944 1008718 F

ATOM 20876 CB ASN F 357 44 144 44610 -3 543 1 0018468 F ATOM 20961 NZ LYS F 367 6088933704 -12943 1008718 F

ATOM 20877 CG ASN F 357 44 944 45 879 -3 387 1 00138 60 F ATOM 20962 C LYS F 367 58869 40680 -11867 1008098 F ATOM 20878 ODl ASN F 357 45 595 46087 -2 365 1 00138 60 F ATOM 20963 O LYS F 367 57863 41034-12482 1008129 F ATOM 20879 ND2 ASN F 357 44 905 46736 -4401 1 00138 60 F ATOM 20964 N TRP F 368 59978 41409 -11796 1007536 F

ATOM 20880 C ASN F 357 44084 42 172 -3 123 1 00 83 18 F ATOM 20965 CA TRP F 368 6010042680 -12498 1007542 F

ATOM 20881 O ASN F 357 43 456 41 665 -4 050 1 00 8606 F ATOM 20966 CB TRP F 368 6074043742 -11602 10012550 F

ATOM 20882 N SER F 358 44013 41 773 -1 858 1 008798 F ATOM 20967 CG TRP F 368 5984444176 -10494 10010542 F

ATOM 20883 CA SER F 358 43 208 40 662 -1 377 1 00 95 28 F ATOM 20968 CD2 TRP F 368 5884745203-10551 10010542 F

ATOM 20884 CB SER F 358 41 827 41 164 -0 942 1 00 87 42 F ATOM 20969 CE2 TRP F 368 5819845227 -9298 10010542 F

ATOM 20885 OG SER F 358 41 078 41 621 -2 049 1 00 85 76 F ATOM 20970 CE3 TRP F 368 5843746102-11541 10010542 F

ATOM 20886 C SER F 358 43 064 39 466 -2 317 1 0010000 F ATOM 20971 CDl TRP F 368 59765 43636 -9244 10010542 F

ATOM 20887 O SER F 358 42 135 39 389 -3 130 1 0095 55 F ATOM 20972 NEl TRP F 368 5877944262 -8518 10010542 F

ATOM 20888 N FHE F 359 43 998 38 527 -2 159 1 00 85 09 F ATOM 20973 CZ2 TRP F 368 5716546115 -9008 10010542 F

ATOM 20889 CA PHE F 359 44 064 37 277 -2 922 1 00 79 40 F ATOM 20974 CZ3 TRP F 368 5740846985 -11252 10010542 F

ATOM 20890 CB PHE F 359 45 371 37244 -3 708 1 00 84 97 F ATOM 20975 CH2 TRP F 368 5678446984 -9994 10010542 F

ATOM 20891 CG PHE F 359 46 583 37 643 -2 900 1 00 79 57 F ATOM 20976 C TRP F 368 6094642476 -13748 1007737 F ATOM 20892 CDl PHE F 359 47225 36 722 -2 073 1 00 7957 F ATOM 20977 O TRP F 368 6212642140-13665 1007756 F ATOM 20893 CD2 PHE F 359 47 098 38 938 2 988 1 00 79 57 F ATOM 20978 N ILE F 369 6033742690 -14905 1007842 F ATOM 20894 CEl PHE F 359 48 366 37 082 -1 347 1 00 79 57 F ATOM 20979 CA ILE F 369 61026 42493 -16167 1007979 F ATOM 20895 CE2 PHE F 359 48 244 39 313 -2 264 1 00 79 57 F ATOM 20980 CB ILE F 369 60411 41298-16916 10011904 F ATOM 20896 CZ PHE F 359 48 878 38 383 -1 444 1 00 79 57 F ATOM 20981 CG2 ILE F 369 61183 41027-18191 1009672 F

ATOM 20897 C PHE F 359 44 030 36 144 -1 895 1 00 85 99 ATOM 20982 CGl ILE F 369 6041740067 16011 1009672 F

ATOM 20898 O PHE F 359 44 575 36 318 0 809 1 00 83 54 F ATOM 20983 CDl ILE F 369 59681 38887-16590 1009672 F

ATOM 20899 N TYR F 360 43410 34997 -2 180 1 0012841 F ATOM 20984 C ILE F 369 6093043728 -17056 1008161 F ATOM 20900 CA TYR F 360 43 429 34 003 -1 119 1 00128 19 F ATOM 20985 O ILE F 369 59859 44317-17196 1007841 F

ATOM 20901 CB TYR F 360 42 275 32 999 -1 125 1 00200 84 F ATOM 20986 N GLU F 370 62049 44120-17657 1009263 F ATOM 20902 CG TYR F 360 42 594 31 931 -0074 1 00113 61 F ATOM 20987 CA GLU F 370 6204945272 -18547 1009528 F ATOM 20903 CDl TYR F 360 43 043 32 305 1 203 1 00113 61 F ATOM 20988 CB GLU F 370 6346245514-19073 10013877 F ATOM 20904 CEl TYR F 360 43 529 31 363 2 117 1 00113 61 F ATOM 20989 CG GLU F 370 6435646167-18032 10011741 F ATOM 20905 CD2 TYR F 360 42 624 30574 -0395 1 00113 61 F ATOM 20990 CD GLU F 370 6582046190-18423 10011741 F ATOM 20906 CE2 TYR F 360 43 105 29 619 0 524 1 00113 61 F ATOM 20991 OEl GLU F 370 6613646589-19563 10011741 F ATOM 20907 CZ TYR F 360 43 558 30025 1 770 1 00113 61 F ATOM 20992 OE2 GLU F 370 6666045816-17578 10011741 F

ATOM 20908 OH TYR F 360 44 047 29 098 2 663 1 00113 61 F ATOM 20993 C GLU F 370 6106445007-19686 1009546 F

ATOM 20909 C TYR F 360 44 683 33 187 0913 1 0012928 F ATOM 20994 O GLU F 370 61083 43940-20295 1009431 F

ATOM 20910 O TYR F 360 45 465 33 515 -0031 1 00135 21 F ATOM 20995 N SER F 371 60195 45975-19963 1009801 F

ATOM 20911 N PRO F 361 44 882 32 094 -1 680 1 0073 77 F ATOM 20996 CA SER F 371 59171 45832-21001 1009855 F

ATOM 20912 CD PRO F 361 44 398 31 769 -3 035 1 00 76 87 F ATOM 20997 CB SER F 371 5831847096-21064 1009916 F

ATOM 20913 CA PRO F 361 46 131 31 385 -1 363 1 00 69 36 F ATOM 20998 OG SER F 371 5912248216-21371 1008824 F

ATOM 20914 CB PRO F 361 46 330 30455 -2 566 1 00 76 11 F ATOM 20999 C SER F 371 5966045492 -22410 1009782 F 65251/C766

ATOM 21000 O SER F 371 5889644954 23215 1009876 F ATOM 21085 O TYR F 380 53222 3385O-2OI58 1006879 F ATOM 21001 N GLU F 372 60915 45808-22716 1009277 F ATOM 21086 N VAL F 381 54982 34294 -21487 1005022 F

ATOM 21002 CA GLU F 372 61458 45506-24035 1009132 F ATOM 21087 CA VAL F 381 54953 32977 -22126 1005022 F

ATOM 21003 CB GLU F 372 6293845890-24104 10012765 F ATOM 21088 CB VAL F 381 55613 33020-23521 1005703 F

ATOM 21004 CG GLU F 372 63801 45201 -23061 10012765 F ATOM 21089 CGl VALF 381 55448 31682-24218 1005703 F

ATOM 21005 CD GLU F 372 65282 45333-23346 10012765 F ATOM 21090 CG2VALF381 54982 34111 -24348 1005703 F

ATOM 21006 OEl GLU F 372 6572744818-24394 10012765 F ATOM 21091 C VAL F 381 55658 31924-21256 1005022 F

ATOM 21007 OE2 GLU F 372 6600045947 -22526 10012765 F ATOM 21092 O VAL F 381 5685632038 -20967 1005022 F

ATOM 21008 C GLU F 372 6131444015-24341 1009593 F ATOM 21093 N ASN F 382 5490830892 -20869 1007652 F

ATOM 21009 O GLU F 372 6099743626-25468 1009700 ATOM 21094 CA ASN F 382 55421 29846 -20000 1007652 F ATOM 21010 N HISF373 61538 43191 -23320 10011062 F ATOM 21095 CB ASN F 382 5457428586 -20108 1005496 F

ATOM 21011 CA HIS F 373 6146241744-23453 10011411 F ATOM 21096 CG ASN F 382 54668 27717-18854 1005496 F

ATOM 21012 CB HIS F 373 61961 41081 -22176 10013360 F ATOM 21097 ODl ASN F 382 55701 27692-18166 1005496 F

ATOM 21013 CG HIS F 373 6338941393-21864 10010295 F ATOM 21098 ND2 ASNF382 5359226990 -18560 1005496 F

ATOM 21014 CD2 HIS F 373 6397041915-20758 10010295 F ATOM 21099 C ASN F 382 5688029462 -20180 1007652 F

ATOM 21015 NDl HIS F373 64409 41171 -22764 10010295 F ATOM 21100 O ASN F 382 5774429899-19421 1007652 F

ATOM 21016 CEl HIS F 373 6555741542 -22226 10010295 F ATOM 21101 N GLY F 383 5718028647-21173 1004241 F

ATOM 21017 NE2HISF373 65318 41998-21009 10010295 F ATOM 21102 CA GLY F 383 5856928244-21314 1004241 F

ATOM 21018 C HIS F 373 6009741 191 -23808 10010988 F ATOM 21103 C GLY F 383 59582 29267 -21810 I 004241 F

ATOM 21019 O HIS F 373 59973 40003-24092 10010572 F ATOM 21104 O GLY F 383 60752 28942 -21997 1004241 F

ATOM 21020 N PHE F 374 5906942029-23790 1008214 F ATOM 21105 N ARG F 384 59161 30505 22022 1006607 F ATOM 21021 CA PHE F 374 5774641549-24149 1008291 F ATOM 21106 CA ARG F 384 6008631501 -22536 1006607 F

ATOM 21022 CB PHE F 374 56685 42104 -23207 10010956 F ATOM 21107 CB ARG F 384 59303 32672 -23129 1006793 F

ATOM 21023 CG PHE F 374 56731 41493-21850 1008974 F ATOM 21108 CG ARG F 384 60163 33689 -23871 1006793 F

ATOM 21024 CDl PHE F 374 5764741941 -20906 1008974 F ATOM 21109 CD ARG F 384 5929634579 -24742 1006793 F

ATOM 21025 CD2PHEF374 55911 40417-21535 1008974 F ATOM 21110 NE ARG F 384 58553 33780 -25712 1006793 F

ATOM 21026 CEl PHE F 374 57751 41327-19669 1008974 F ATOM 21111 CZ ARG F 384 57561 34238-26472 1006793 F

ATOM 21027 CE2 PHE F 374 5600639793 -20301 1008974 F ATOM 21112 NHl ARG F 384 57180 35503 -26383 1006793 F

ATOM 21028 CZ PHE F 374 56931 40250-19364 I 008974 F ATOM 21113 NH2 ARG F 384 56938 33426-27319 1006793 F

ATOM 21029 C PHE F 374 57393 41884-25585 1007899 F ATOM 21114 C ARG F 384 6107432005 -21496 1006607 F

ATOM 21030 O PHE F 374 5624041740-25993 1007723 F ATOM 21115 O ARG F 384 6077432043 -20307 1006607 F

ATOM 21031 N LYSF375 58401 42316-26344 10011584 F ATOM 21116 N TYR F 385 6226032382 -21953 1007043 F

ATOM 21032 CA LYS F 375 5825042669-27757 10011847 F ATOM 21117 CA TYR F 385 63288 32901 -21065 1007043 F

ATOM 21033 CB LYS F 375 58713 41506 -28651 100126 S3 F ATOM 21118 CB TYR F 385 64675 32622 -21644 10010479 F

ATOM 21034 CG LYS F 375 60225 41377-28843 10010067 F ATOM 21119 CG TYR F 385 65767 33321 -20879 10010479 F

ATOM 21035 CD LYS F 375 60947 40915-27586 I 0010067 F ATOM 21120 CDl TYR F 385 66179 32850 -19636 10010479 F

ATOM 21036 CE LYS F 375 6243240697 -27852 10010067 F ATOM 21121 CEl TYR F 385 67121 33539-18882 10010479 F

ATOM 21037 NZ LYS F 375 6317940304-26620 10010067 F ATOM 21122 CD2 TYR F 385 66331 34502-21357 10010479 F

ATOM 21038 C LYS F 375 5683643075 28169 10012349 F ATOM 21123 CE2TYRF385 67273 35200-20610 10010479 F

ATOM 21039 O LYSF375 5627042503-29098 10012575 F ATOM 21124 CZ TYR F 385 67662 34714-19374 10010479 F

ATOM 21040 N GLY F 376 5626044050-27475 1007905 F ATOM 21125 OH TYR F 385 68577 35415-18622 10010479 F

ATOM 21041 CA GLY F 376 5492444502 27830 1007905 F ATOM 21126 C TYR F 385 6312634414 -20880 1007043 F

ATOM 21042 C GLY F 376 53731 43764-27240 1007905 F ATOM 21127 O TYR F 385 6279835131 21830 1007043 F

ATOM 21043 O GLY F 376 5268244373-27020 1007905 F ATOM 21128 N TYR F 386 63362 34903 -19663 1007685 F

ATOM 21044 N GLU F 377 53863 42464-26995 10011485 F ATOM 21129 CA TYR F 386 63253 36338-19381 1007685 F

ATOM 21045 CA GLU F 377 52761 41690-26426 10011485 F ATOM 21130 CB TYR F 386 61881 36712-18800 1007981 F

ATOM 21046 CB GLU F 377 5262640346-27142 10012654 F ATOM 21131 CG TYR F 386 60675 36494-19680 1007981 F

ATOM 21047 CG GLU F 377 51350 39596-26796 10012654 F ATOM 21132 CDl TYR F 386 59912 35337-19566 1007981 F

ATOM 21048 CD GLU F 377 51222 38287-27549 10012654 F ATOM 21133 CEl TYR F 386 58771 35147 -20337 1007981 F

ATOM 21049 OEl GLU F 377 5014737657 -27459 10012654 F ATOM 21134 CD2 TYR F 386 60271 37463-20598 1007981 F

ATOM 21050 OE2 GLU F 377 52195 37888 -28228 10012654 F ATOM 21135 CE2TYRF386 59128 37281 -21378 1007981 F

ATOM 21051 C GLUF377 5300641462-24937 10011485 F ATOM 21136 CZ TYR F 386 58381 36118-21239 1007981 F

ATOM 21052 O GLU F 377 53989 40827-24552 10011485 F ATOM 21137 OH TYR F 386 57241 35928-21991 1007981 F

ATOM 21053 N TYRF378 5210841979 -24100 1008259 F ATOM 21138 C TYR F 386 64273 36815-18359 1007685 F

ATOM 21054 CA TYR F 378 52256 41845 -22657 1008259 F ATOM 21139 O TYR F 386 64338 36277 -17254 1007685 F

ATOM 21055 CB TYR F 378 5175643111-21962 1008477 F ATOM 21140 N PRO F 387 6509637817-18708 10010709 F

ATOM 21056 CG TYR F 378 52659 44292 -22223 1008477 F ATOM 21141 CD PRO F 387 6534438395-20038 1OO6Θ88 F

ATOM 21057 CD1 TYRF378 5240645179-23270 1008477 F ATOM 21142 CA PRO F 387 66073 38312-17729 10010709 F

ATOM 21058 CEl TYR F 378 53297 46213 -23568 1008477 F ATOM 21143 CB PRO F 387 66848 39356-18523 1006688 F

ATOM 21059 CD2 TYR F 378 53823 44472 -21476 1008477 F ATOM 21144 CG PRO F 387 66783 38828 -19924 1006688 F

ATOM 21060 CE2TYRF378 54718 45500 21768 1008477 F ATOM 21145 C PRO F 387 65146 38936-16684 10010709 F

ATOM 21061 CZ TYR F 378 5445346364-22813 1008477 F ATOM 21146 O PRO F 387 64099 39465-17062 10010709 F

ATOM 21062 OH TYR F 378 55358 47359-23113 1008477 F ATOM 21147 N GLU F 388 6548038915-15396 100131 10 F

ATOM 21063 C TYR F 378 5162340614 -22034 1008259 F ATOM 21148 CA GLU F 388 64488 39456-14472 10013110 F

ATOM 21064 O TYR F 378 5067640705 -21256 1008259 F ATOM 21149 CB GLU F 388 63648 38300-13929 10013096 F

ATOM 21065 N LYS F 379 52171 39461-22400 1007768 F ATOM 21150 CG GLU F 388 64391 37376-12987 10013096 F ATOM 21066 CA LYS F 379 5174638167 -21886 1007768 F ATOM 21151 CD GLU F 388 6345536427-12268 10013096 F

ATOM 21067 CB LYS F 379 50992 37369 -22950 10011155 F ATOM 21152 OEl GLU F 388 62532 36913-11580 10013096 F

ATOM 21068 CG LYS F 379 49644 37947-23331 10011155 F ATOM 21153 OE2GLUF388 63642 35199-12392 10013096 F

ATOM 21069 CD LYS F 379 48982 37092-24401 10011155 F ATOM 21154 C GLU F 388 64747 40409-13306 10013110 F

ATOM 21070 CE LYS F 379 47705 37726-24938 10011155 F ATOM 21155 O GLU F 388 63905 40483-12412 10013110 F

ATOM 21071 NZ LYS F379 4715936966 -26105 10011155 F ATOM 21156 N TRP F 389 65851 41144-13274 10010063 F

ATOM 21072 C LYS F 379 53034 37445-21526 1007768 F ATOM 21157 CA TRP F 389 6603842076-12153 10010063 F

ATOM 21073 O LYS F 379 5402737537-22252 1007768 F ATOM 21158 CB TRP F 389 6500643208-12236 10011057 F

ATOM 21074 N TYR F 380 5303036752 -20394 1006879 F ATOM 21159 CG TRP F 389 6547244474-12874 10011057 F

ATOM 21075 CA TYR F 380 54209 36012-19951 1006879 F ATOM 21160 CD2 TRP F 389 66813 44812-13258 10011057 F

ATOM 21076 CB TYR F 380 5422735928-18427 1006858 F ATOM 21161 CE2TRPF389 6677646125-13777 10011057 F ATOM 21077 CG TYR F 380 5546035281 -17862 1006858 F ATOM 21162 CE3 TRP F 389 68042 44136 13211 10011057 F ATOM 21078 CDl TYR F 380 5661636023-17637 1006858 F ATOM 21163 CDl TRP F 389 6470445561 -13170 10011057 F

ATOM 21079 CEl TYR F 380 57760 35424 17106 1006858 F ATOM 21164 NEl TRP F 389 6547746556 -13712 10011057 F ATOM 21080 CD2TYRF38O 55471 3392O-I7548 1006858 F ATOM 21165 CZ2TRPF389 6792246778 14248 10011057 F

ATOM 21081 CE2TYRF380 56605 33310-17021 1006858 F ATOM 21166 CZ3TRPF389 69183 44785-13679 10011057 F

ATOM 21082 CZ TYR F 380 57748 34067-16800 1006858 F ATOM 21167 CH2 TRP F 389 69113 46094-14190 10011057 F

ATOM 21083 OH TYR F 380 5887633484-16267 1006858 F ATOM 21168 C TRP F 389 6586441392 -10799 10010063 F

ATOM 21084 C TYR F 380 54103 34617-20543 1006879 F ATOM 21169 O TRP F 389 6487041629 -10109 10010063 F 65251/C766

ATOM 21170 N GLY F 390 66 824 40 562 -10 411 1 00116 80 F ATOM 21255 O PRO F 400 59436 33231 4413 1006450 F ATOM 21171 CA GLY F 390 66 713 39 868 -9 140 1 00116 80 F ATOM 21256 N GLY F 401 61343 32131 3996 1007345 F ATOM 21172 C GLY F 390 66706 40771 -7921 1 0011680 F ATOM 21257 CA GLY F 401 62157 33209 4528 1007301 F ATOM 21173 O GLY F 390 67234 41 879 -7958 1 00116 80 F ATOM 21258 C GLY F 401 62273 34441 3639 1007280 F ATOM 21174 N ARG F 391 66094 40 294 6 841 1 00115 28 F ATOM 21259 O GLY F 401 62801 35465 4066 1007351 F ATOM 21175 CA ARG F 391 66 034 41 036 -5 588 1 00115 28 F ATOM 21260 N PHE F 402 61789 34364 2405 10010417 F ATOM 21176 CB ARG F 391 64 736 40698 -4 842 1 00111 27 F ATOM 21261 CA PHE F 402 61879 35511 1512 10010417 F ATOM 21177 CG ARG F 391 63 457 41 013 -5 622 1 00111 27 F ATOM 21262 CB PHE F 402 61517 35116 0086 10017424 F ATOM 21178 CD ARG F 391 62 850 42 382 -5 271 1 00111 27 F ATOM 21263 CG PHE F 402 62057 36059 -0939 1007257 F ATOM 21179 NE ARG F 391 61 874 42 320 -4 176 1 00111 27 F ATOM 21264 CDl PHE F 402 63410 36034 -1275 1007257 F ATOM 211S0 CZ ARG F 391 62 180 42222 -2 881 1 00111 27 F ATOM 21265 CD2 PHE F402 61233 37012 -1528 1007257 F ATOM 21181 NHl ARG F 391 63 448 42 180 -2489 1 00111 27 F ATOM 21266 CEl PHE F 402 63937 36949 -2185 1007257 F ATOM 21182 NH2 ARG F 391 61 212 42 159 -1 972 1 00111 27 F ATOM 21267 CE2 PHE F 402 61749 37936 -2439 1007257 F ATOM 21183 C ARG F 391 67256 40 596 -4 771 1 00115 28 ATOM 21268 CZ PHE F 402 63106 37904 -2769 1007257 F ATOM 21184 O ARG F 391 67 916 39 618 -5 121 1 001 15 28 F ATOM 21269 C PHE F 402 60962 36642 1977 10010417 F ATOM 21185 N LYS F 392 67 572 41 312 -3 697 1 00 97 75 F ATOM 21270 O PHE F 402 59778 36425 2237 10010417 F ATOM 21186 CA LYS F 392 68 724 40 952 -2 873 1009775 F ATOM 21271 N PRO F 403 61503 37870 2075 10010690 F ATOM 21187 CB LYS F 392 69 654 42 156 -2 695 10012182 F ATOM 21272 CD PRO F 403 62908 38200 1791 1008617 F ATOM 21188 CG LYS F 392 70 879 41 851 -1 854 10012182 F ATOM 21273 CA PRO F 403 60783 39071 2506 10010690 F ATOM 21189 CD LYS F 392 71 641 43 110 -1 494 10012182 F ATOM 21274 CB PRO F 403 61893 40114 2677 10019100 F ATOM 21190 CE LYS F 392 72 766 42 806 -0510 10012182 F ATOM 21275 CG PRO F 403 63151 39323 2748 1008617 F ATOM 21191 NZ LYS F 392 73423 44048 -0003 10012182 F ATOM 21276 C PRO F 403 59738 39566 1515 10010690 F ATOM 21192 C LYS F 392 68291 40437 -1501 1009775 F ATOM 21277 O PRO F 403 60077 40194 0512 10010690 F ATOM 21193 O LYS F 392 67724 41 181 -0700 1009775 F ATOM 21278 N TRP F 404 58472 39277 1785 10011741 F ATOM 21194 N SER F 393 68569 39163 -1234 10010121 F ATOM 21279 CA TRP F 404 57393 39755 0930 10011741 F ATOM 21195 CA SER F 393 68209 38536 0038 10010121 F ATOM 21280 CB TRP F 404 56551 38602 0375 10010551 F ATOM 21196 CB SER F 393 66708 38221 0070 1006415 F ATOM 21281 CG TRP F 404 57192 37820 0737 1009875 F ATOM 21197 OG SER F 393 66342 37527 1253 1006415 F ATOM 21282 CD2 TRP F 404 57599 38311 -2025 1009875 F ATOM 21198 C SER F 393 68994 37244 0206 10010121 F ATOM 21283 CE2 TRP F 404 58109 37212 -2746 1009875 F ATOM 21199 O SER F 393 69481 36682 -0773 10010121 F ATOM 21284 CE3 TRP F 404 57582 39571 -2638 1009875 F ATOM 21200 N ASN F 394 69126 36776 1443 10010711 F ATOM 21285 CDl TRP F 404 57467 36484 -0735 1009875 F ATOM 21201 CA ASN F 394 69842 35530 1688 10010711 F ATOM 21286 NEl TRP F 404 58016 36112 -1935 1009875 F ATOM 21202 CB ASN F 394 70246 35414 3151 1009791 F ATOM 21287 CZ2 TRP F 404 58598 37332 -4054 1009875 F ATOM 21203 CG ASN F 394 71356 36364 3515 1009791 F ATOM 21288 CZ3 TRP F 404 58070 39689 -3943 1009875 F ATOM 21204 ODl ASN F 394 72380 36429 2831 1009791 F ATOM 21289 CH2 TRP F 404 58570 38576 -4632 1009875 F ATOM 21205 ND2 ASN F 394 71 166 37106 4602 1009791 F ATOM 21290 C TRP F 404 56529 40607 1841 10011741 F ATOM 21206 C ASN F 394 68945 34368 1311 10010711 F ATOM 21291 O TRP F 404 56168 40170 2935 10011741 F ATOM 21207 O ASN F 394 69410 33250 1 100 10010711 F ATOM 21292 N ASN F 405 56208 41821 1406 1007358 F ATOM 21208 N TYR F 395 67650 34651 1233 1006427 F ATOM 21293 CA ASN F 405 55378 42702 2219 1007361 F ATOM 21209 CA TYR F 395 66667 33656 0855 1006427 F ATOM 21294 CB ASN F 405 55550 44152 1 767 1009330 F ATOM 21210 CB TYR F 395 65384 33858 1656 1008082 F ATOM 21295 CG ASN F 405 55189 45139 2851 1009330 F ATOM inn CG TYR F 395 65554 33665 3137 I 008082 F ATOM 21296 ODl ASN F 405 54018 45303 3194 1009330 F ATOM 21212 CDl TYR F 395 65815 34745 3976 1008082 F ATOM 21297 ND2 ASN F 405 56201 45794 3412 1009330 F ATOM 21213 CEl TYR F 395 65973 34566 5355 1008082 F ATOM 21298 C ASN F 405 53910 42284 2130 1008255 F ATOM 21214 CD2 TYR F 395 65456 32397 3705 1008082 F ATOM 21299 O ASN F 405 53096 42926 1460 1007561 F ATOM 21215 CE2 TYR F 395 65612 32205 5076 1008082 F ATOM 21300 N ILE F 406 53585 41 190 2807 1009534 F ATOM 21216 CZ TYR F 395 65871 33296 5898 1008082 F ATOM 21301 CA ILE F 406 52228 40670 2815 1008754 F ATOM 21217 OH TYR F 395 66029 33109 7256 1008082 F ATOM 21302 CB ILE F 406 52195 39165 2455 1008880 F ATOM 21218 C TYR F 395 66349 33782 -0633 1006427 F ATOM 21303 CG2 ILE F406 50750 38676 2353 1007642 F ATOM 21219 O TYR F 395 66518 34845 -1227 1006427 F ATOM 21304 CGl ILE F 406 52924 38935 1 130 1007642 F ATOM 21220 N GLU F 396 65890 32689 -1234 1008494 F ATOM 21305 CDl ILE F 406 52903 37495 0652 1007642 F ATOM 21221 CA GLU F 396 65512 32680 -2645 1008494 F ATOM 21306 C ILE F 406 51628 40839 4198 1009441 F ATOM 21222 CB GLU F 396 65998 31402 -3325 I 0015021 F ATOM 21307 O ILE F 406 52311 40679 5210 1008951 F ATOM 21223 CG GLU F 396 67445 31056 -3062 10015021 F ATOM 21308 N LYS F 407 50348 41 179 4238 10091 19 F ATOM 21224 CD GLU F 396 67789 29658 -3539 10015021 F ATOM 21309 CA LYS F 407 49636 41346 5495 1008679 F ATOM 21225 OEl GLU F 396 67085 28705 -3135 10015021 F ATOM 21310 CB LYS F 407 49506 42822 5871 10010753 F ATOM 21226 OE2 GLU F 396 68761 29509 -4312 10015021 F ATOM 21311 CG LYS F 407 50816 43540 6117 1009363 F ATOM 21227 C GLU F 396 63986 32702 -2672 1008494 F ATOM 21312 CD LYS F 407 50562 44928 6695 1009363 F ATOM 21228 O GLU F 396 63338 32030 -1863 1008494 F ATOM 21313 CE LYS F 407 51843 45739 6822 1009363 F ATOM 21229 N PRO F 397 63385 33474 -3593 1007685 F ATOM 21314 NZ LYS F 407 52437 46048 5487 1009363 F ATOM 21230 CD PRO F 397 63955 34244 -4712 1007614 F ATOM 21315 C LYS F 407 4826040776 5249 1009610 F ATOM 21231 CA PRO F 397 61918 33501 -3630 1007685 F ATOM 21316 O LYS F 407 47700 40950 4166 1009504 F ATOM 21232 CB PRO F 397 61610 34322 -4884 1007614 F ATOM 21317 N LYS F 408 47719 40070 6231 10010037 F ATOM 21233 CG PRO F 397 62851 34160 -5731 1007614 F ATOM 21318 CA LYS F 408 46386 39521 6067 1009996 F ATOM 21234 C PRO F 397 61369 32081 -3680 1007685 F ATOM 21319 CB LYS F 408 46093 38483 7145 1007189 F ATOM 21235 O PRO F 397 61846 31241 -4437 1007685 F ATOM 21320 CG LYS F 408 44769 37781 6946 1007069 F ATOM 21236 N GLY F 398 60370 31822 2851 1004727 F ATOM 21321 CD LYS F 408 44653 36575 7853 1007069 F ATOM 21237 CA GLY F 398 59787 30497 -2775 1004727 F ATOM 21322 CE LYS F 408 43369 35810 7578 1007069 F ATOM 21238 C GLY F 398 59984 29982 -1357 1004727 F ATOM 21323 NZ LYS F 408 43316 34552 8371 1007069 F ATOM 21239 O GLY F 398 59087 29349 -0788 1004727 F ATOM 21324 C LYS F 408 4546440715 6226 10010009 F ATOM 21240 N GLU F 399 61 163 30248 -0788 1008515 F ATOM 21325 O LYS F 408 45311 41233 7328 1009866 F ATOM 21241 CA GLU F 399 61471 29829 0580 1008515 F ATOM 21326 N ASP F 409 44857 41 173 5137 10014626 F ATOM 21242 CB GLU F 399 62969 30004 0887 1007685 F ATOM 21327 CA ASP F 409 43997 42340 5250 10014644 F ATOM 21243 CG GLU F 399 63897 29317 -0102 1007685 F ATOM 21328 CB ASP F 409 43546 42840 3862 10012744 F ATOM 21244 CD GLU F 399 6537629451 0247 1007685 F ATOM 21329 CG ASP F 409 43053 41729 2954 10012026 F ATOM 21245 OEl GLU F 399 65804 30563 0602 1007685 F ATOM 21330 ODl ASP F 409 42241 40898 3412 10012026 F ATOM 21246 OE2 GLU F 399 66119 28449 0147 1007685 F ATOM 21331 OD2 ASP F409 43468 41700 1772 10012026 F ATOM 21247 C GLU F 399 60648 30737 1491 1008515 F ATOM 21332 C ASP F 409 42798 42145 6178 10014635 F ATOM 21248 O GLU F 399 60553 31941 1245 1008515 F ATOM 21333 O ASP F 409 42441 41015 6530 10015008 F ATOM 21249 N PRO F 400 60021 30178 2542 1007846 F ATOM 21334 N LYS F 410 42222 43278 6586 10012814 F ATOM 21250 CD PRO F 400 59909 28778 2978 1005739 F ATOM 21335 CA LYS F 410 41067 43366 7482 10013458 F ATOM 21251 CA PRO F 400 59233 31059 3410 1007354 F ATOM 21336 CB LYS F 410 40192 44562 7088 10017588 F ATOM 21252 CB PRO F 400 58676 30107 4473 10010600 F ATOM 21337 CG LYS F 410 39471 44420 5741 10011533 F ATOM 21253 CG PRO F 400 59596 28944 4437 1005739 F ATOM 21338 CD LYS F 410 40421 44527 4543 10011533 F ATOM 21254 C PRO F 400 60019 32233 3997 1006429 F ATOM 21339 CE LYS F 410 39683 44337 3213 10011533 F 65251/C766

ATOM 21340 NZ LYS F 410 40 591 44 427 2028 1 00115 33 F ATOM 21425 C VAL F 421 62152 49935 -7141 10012750 F ATOM 21341 C LYS F 410 40 195 42 120 7 546 1 00133 40 F ATOM 21426 O VAL F 421 61514 50923 -7499 10012310 F ATOM 21342 O LYS F 410 40 145 41 336 6 600 1 00132 93 F ATOM 21427 N ARG F 422 63474 49933 -6992 10010521 F ATOM 21343 N ASP F411 39495 41 962 8 666 1 00 86 87 F ATOM 21428 CA ARG F 422 64297 51 113 -7236 10010734 F ATOM 21344 CA ASP F 411 38 611 40 819 8 894 1 00 84 38 F ATOM 21429 CB ARG F 422 65611 50978 6465 10018193 F ATOM 21345 CB ASP F 411 37 361 41 253 9 666 1 00183 80 F ATOM 21430 CG ARG F 422 65932 52127 -5528 10014252 F ATOM 21346 CG ASP F 411 37 557 41 200 11 168 1 00183 80 F ATOM 21431 CD ARG F 422 66472 53337 -6272 10014252 F ATOM 21347 ODl ASP F 411 37 996 40 144 11 672 1 00183 80 F ATOM 21432 NE ARG F 422 66917 54376 5346 10014252 F ATOM 21348 OD2 ASP F 41 1 37266 42206 11 847 1 00183 80 F ATOM 21433 CZ ARG F 422 67559 55484 -5706 10014252 F ATOM 21349 C ASP F411 38 179 40060 7 643 1 00 85 99 F ATOM 21434 NHl ARG F 422 67838 55710 -6984 10014252 F ATOM 21350 O ASP F 411 37091 40284 7 107 1 0090 17 F ATOM 21435 NH2 ARG F 422 67927 56366 -4786 10014252 F ATOM 21351 N ALA F 412 39043 39 150 7 197 1 00178 26 F ATOM 21436 C ARG F 422 64590 51243 -8730 10010457 F ATOM 21352 CA ALA F 412 38790 38 330 6 016 1 00191 28 F ATOM 21437 O ARG F 422 65470 50559 -9250 1009524 F ATOM 21353 CB ALA F 412 38 813 39 190 4 759 1 00 6070 F ATOM 21438 N THR F 423 63861 52120 -9417 10013246 F ATOM 21354 C ALA F412 39 846 37236 5 913 1 00185 98 F ATOM 21439 CA THR F 423 64050 52313-10855 10014211 F ATOM 21355 O ALA F 412 40 822 37227 6 662 1 00181 03 F ATOM 21440 CB THR F 423 62895 53 147 -11480 10019579 F ATOM 21356 N ASN F413 39 645 36316 4 977 1 00124 87 F ATOM 21441 OGl THR F 423 61640 52519-11 199 10015158 ATOM 21357 CA ASN F 413 40 579 35 218 4775 1 00117 68 F F ATOM 21358 CB ASN F 413 39 839 33 986 4266 1 00 93 50 ATOM 21442 CG2 THR F 423 63056 53248-12996 10015158 F ATOM 21359 CG ASN F 413 38 798 33 496 5 238 1 00 93 50 F ATOM 21443 C THR F 423 65365 53014-11 178 10014033 F ATOM 21360 ODl ASN F413 39035 33459 6447 1 0093 50 F ATOM 21444 O THR F 423 65363 54120-11712 10013882 F ATOM 21361 ND2 ASN F 413 37 640 33 102 4 720 1 0093 50 F ATOM 21445 N THR F 424 66488 52379-10855 10017573 F ATOM 21362 C ASN F 413 41 651 35 581 3 769 1 00122 26 F ATOM 21446 CA THR F 424 67788 52975-11 143 10017573 F ATOM 21363 O ASN F 413 42 674 34909 3 663 1 00121 95 F ATOM 21447 CB THR F 424 68941 52112 10594 10019950 F ATOM 21364 N THR F 414 41 408 36 656 3 034 1 00 72 74 F ATOM 21448 OGl THR F 424 68768 51931 -9184 10014531 F ATOM 21365 CA THR F 414 42312 37 1 11 1 998 1 00 75 78 F ATOM 21449 CG2 THR F 424 70286 52789-10846 10014531 F ATOM 21366 CB THR F 414 41 517 37 960 0999 1 00129 14 ATOM 21450 C THR F 424 67938 53114-12655 10017573 F ATOM 21367 OGl THR F 414 42 390 38415 -0 029 1 00 99 63 F ATOM 21451 O THR F 424 67298 52391-13419 10017573 F ATOM 21368 CG2 THR F414 40 867 39 147 1 690 1 0099 63 ATOM 21452 N SER F 425 68783 54045-13085 10018014 F ATOM 21369 C THR F 414 43 558 37867 2494 1 007524 F ATOM 21453 CA SER F 425 68991 54285-14507 10018014 F ATOM 21370 O THR F 414 43 631 38258 3 659 1 00 7631 F ATOM 21454 CB SER F 425 69680 55634 -14707 10020084 F ATOM 21371 N TYR F 415 44 541 38046 1 608 1 00 61 97 F ATOM 21455 OG SER F 425 69794 55947-16083 10010456 F ATOM 21372 CA TYR F 415 45 796 38 742 1 932 1 00 63 00 F ATOM 21456 C SER F 425 69792 53191-15213 10018014 F ATOM 21373 CB TYR F 415 46 980 37 765 1 966 1 00 93 98 F ATOM 21457 O SER F 425 70018 53266-16420 10018014 F ATOM 21374 CG TYR F 415 46 928 36 741 3 070 1 00 60 92 F ATOM 21458 N LYS F 426 70218 52177-14465 100163 16 F ATOM 21375 CDl TYR F 415 45 966 35 729 3 067 1 00 6092 F ATOM 21459 CA LYS F 426 70991 51076-15038 10016316 F ATOM 21376 CEl TYR F 415 45 905 34 792 4089 1 00 60 92 F ATOM 21460 CB LYS F 426 71305 50039-13961 10020084 F ATOM 21377 CD2 TYR F 415 47835 36789 4 133 1 006092 F ATOM 21461 CG LYS F 426 71933 50610-12712 10014729 F ATOM 21378 CE2 TYR F415 47782 35856 5 167 1 0060 92 F ATOM 21462 CD LYS F 426 72033 49545-11640 10014729 F ATOM 21379 CZ TYR F 415 46816 34862 5 136 1 00 60 92 F ATOM 21463 CE LYS F 426 72523 50129-10330 10014729 F ATOM 21380 OH TYR F 415 46760 33934 6 152 1 00 60 92 F ATOM 21464 NZ LYS F 426 72583 49087 -9268 10014729 F ATOM 21381 C TYR F 415 46119 39816 0900 1007056 F ATOM 21465 C LYS F 426 70228 50391-16171 10016316 F ATOM 21382 O TYR F 415 45575 39814 -0202 1006521 F ATOM 21466 O LYS F 426 70811 50010-17187 10016316 F ATOM 21383 N SER F 416 47028 40719 1254 10073 16 F ATOM 21467 N MET F 427 68920 50236 -15982 10020084 F ATOM 21384 CA SER F 416 47435 41792 0352 10071 11 F ATOM 21468 CA MET F 427 68056 49587-16966 10020084 F ATOM 21385 CB SER F 416 46781 43116 0754 10010494 F ATOM 21469 CB MET F 427 66660 49373-16374 10015914 F ATOM 21386 OG SER F 416 45407 43127 0409 1008132 F ATOM 21470 CG MET F 427 66035 50625-15786 10015914 F ATOM 21387 C SER F 416 48945 41941 0359 1007730 F ATOM 21471 SD MET F 427 64422 50290 -15063 10015914 F ATOM 2138S O SER F 416 49611 41647 1356 1007567 F ATOM 21472 CE MET F 427 64898 49536 -13496 10015914 F ATOM 21389 N LEU F 417 49477 42422 -0756 1005799 F ATOM 21473 C MET F 427 67938 50359-18274 10020084 F ATOM 21390 CA LEU F 417 50916 42577 -0910 1005689 F ATOM 21474 O MET F 427 68766 51218-18578 10020084 F ATOM 21391 CB LEU F 417 51456 41415 -1752 10013010 F ATOM 21475 N SER F 428 66901 50044-19046 10012520 F ATOM 21392 CG LEU F 417 52733 41699 -2548 1008821 F ATOM 21476 CA SER F 428 66682 50704-20325 10012685 F ATOM 21393 CDl LEU F 417 53937 41629 -1629 1008821 F ATOM 21477 CB SER F 428 67786 50310-21310 10012530 F ATOM 21394 CD2 LEU F 417 52864 40705 -3680 1008821 F ATOM 21478 OG SER F 428 67758 48915-21570 10012201 F ATOM 21395 C LEU F 417 51318 43885 -1566 1006840 F ATOM 21479 C SER F 428 65323 50374-20937 10012280 F ATOM 21396 O LEU F 417 50572 44446 -2373 1006350 F ATOM 21480 O SER F 428 65187 50343 -22159 10012268 F ATOM 21397 N THR F 418 52516 44351 -1228 1008304 F ATOM 21481 N SER F 429 64319 50131 -20100 10014053 F ATOM 21398 CA THR F 418 53058 45578 -1792 1007610 F ATOM 21482 CA SER F 429 62985 49809 -20604 10013920 F ATOM 21399 CB THR F418 52938 46754 -0804 10012132 F ATOM 21483 CB SER F 429 62930 48352 -21084 10014171 F ATOM 21400 OGl THR F 418 51566 47148 -0692 1008973 F ATOM 21484 OG SER F 429 63802 48123 -22176 10014171 F ATOM 21401 CG2 THR F 418 53759 47941 -1280 1008973 F ATOM 21485 C SER F 429 61891 50017-19565 10013758 F ATOM 21402 C THR F 418 54526 45369 -2103 1009129 F ATOM 21486 O SER F 429 60707 49955 -19889 10012628 F ATOM 21403 O THR F 418 55321 45176 -1 191 1008476 F ATOM 21487 N GLN F 430 62287 50269-18323 10014886 F ATOM 21404 N ASP F 419 54890 45402 -3381 1007258 F ATOM 21488 CA GLN F 430 61329 50445-17235 10014886 F ATOM 21405 CA ASP F419 56288 45213 -3752 1007769 F ATOM 21489 CB GLN F 430 60301 51521 -17558 10018066 F ATOM 21406 CB ASP F 419 56443 44004 -4680 10015991 F ATOM 21490 CG GLN F 430 59340 51741 -16416 10010965 F ATOM 21407 CG ASP F 419 57888 43547 -4802 10013750 F ATOM 21491 CD GLN F 430 58289 52766-16734 10010965 F ATOM 21408 ODl ASP F 419 58547 43376 -3755 10013750 F ATOM 21492 OEl GLN F 430 57413 52536-17568 10010965 F ATOM 21409 OD2 ASP F419 5836843352 -5936 10013750 F ATOM 21493 NE2 GLN F 430 58370 53915-16075 10010965 F ATOM 21410 C ASP F419 56851 46467 -4416 1008178 F ATOM 21494 C GLN F 430 60615 49120 -17024 10014886 F ATOM 21411 O ASP F 419 56308 46953 -5409 1007667 F ATOM 21495 O GLN F 430 59826 48683-17863 10014886 F ATOM 21412 N LEU F 420 57947 46980 -3861 1007585 F ATOM 21496 N PRO F 431 60863 48473 -15883 1009995 F ATOM 21413 CA LEU F 420 58580 48195 -4362 1008054 F ATOM 21497 CD PRO F 431 61501 48994-14662 10010789 F ATOM 21414 CB LEU F 420 5888649124 -3183 10015601 F ATOM 21498 CA PRO F 431 60225 47191-15616 1009994 F ATOM 21415 CG LEU F 420 59092 50609 -3479 10011496 F ATOM 21499 CB PRO F 431 60799 46804 -14259 10020084 F ATOM 21416 CDl LEU F 420 57787 51200 -3997 10011496 F ATOM 21500 CG PRO F 431 60899 48118-13582 10017741 F ATOM 21417 CD2 LEU F 420 59543 51334 -2216 10011496 F ATOM 21501 C PRO F 431 58711 47230-15612 1009656 F ATOM 21418 C LEU F 420 5986447897 -5133 1008311 F ATOM 21502 O PRO F431 58091 48280-15440 1009644 F ATOM 21419 O LEU F 420 60509 46876 -4901 1008243 F ATOM 21503 N VAL F 432 58139 46054-15828 1007651 F ATOM 21420 N VAL F 421 60234 48790 -6050 10012673 F ATOM 21504 CA VAL F 432 56708 45842 -15823 1007889 F ATOM 21421 CA VAL F 421 61447 48615 -6848 10012524 F ATOM 21505 CB VAL F 432 56236 45289-17173 10011629 F ATOM 21422 CB VAL F 421 61 137 47921 -8188 10013682 F ATOM 21506 CGl VAL F 432 56914 43969 -17472 1008837 F ATOM 21423 CGl VAL F 421 62376 47883 -9065 1009225 F ATOM 21507 CG2 VAL F 432 54758 45114-17151 1008837 F ATOM 21424 CG2 VAL F 421 60667 46522 -7930 1009225 F ATOM 21508 C VAL F 432 56545 44794 -14724 1007689 F 65251/C766

ATOM 21509 O VALF432 5744743981-14499 1006725 F ATOM 21594 NE2 GLN F 443 44801 38363-15113 1007399 F ATOM 21510 N CYSF433 55421 44806-14027 1006803 F ATOM 21595 C GLN F 443 50691 39371 -15430 1008577 F

ATOM 21511 CA CYS F 433 5524243852 -12946 1006391 F ATOM 21596 O GLN F 443 51417 39518-14448 1008683 F

ATOM 21512 C CYSF433 5451842582-13383 1006155 F ATOM 21597 N VAL F 444 50729 40172-16486 1006604 F

ATOM 21513 O CYSF433 5340842648-13919 1006229 F ATOM 21598 CA VAL F 444 51646 41297-16554 1006319 F

ATOM 21514 CB CYSF433 5448444514-11788 10016283 F ATOM 21599 CB VAL F 444 52322 41356 -17937 1008095 F

ATOM 21515 SG CYSF433 54322 43486-10291 10010994 F ATOM 21600 CGl VAL F 444 53546 42247-17877 1007325 F

ATOM 21516 N VALF434 5515441427-13162 1005762 F ATOM 21601 CG2 VAL F 444 52710 39960 -IS 381 1007325 F ATOM 21517 CA VALF434 54553 40138-13498 1005361 F ATOM 21602 C VAL F 444 50891 42608-16291 1006701 F ATOM 21518 CB VALF434 55529 39223 14265 1006210 F ATOM 21603 O VAL F 444 49751 42781 -16727 1006927 F ATOM 21519 CGl VALF434 54792 37975-14743 1004388 F ATOM 21604 N TYRF445 51523 43518 15556 1007612 F

ATOM 21520 CG2VALF434 56135 39969-15442 1004388 F ATOM 21605 CA TYR F 445 50922 44809 -15238 1007519 F

ATOM 21521 C VALF434 54175 39464 12187 1006401 F ATOM 21606 CB TYR F 445 50428 44808-13807 1008860 F

ATOM 21522 O VALF434 55035 39180-11358 1005507 F ATOM 21607 CG TYR F 445 49414 43730-13552 1006102 F

ATOM 21523 N VALF435 5288439211 -12016 1006976 F ATOM 21608 CDl TYR F 445 49805 42463-13115 1006102 F ATOM 21524 CA VAL F435 52364 38604 -10797 1006150 F ATOM 21609 CEl TYR F 445 48858 41461 -12864 1006102 F ATOM 21525 CB VAL F 435 51106 39359-10319 1008143 F ATOM 21610 CD2 TYR F 445 48056 43975 -13741 1006102 F ATOM 21526 CGl VAL F 435 50418 38599 -9199 1006076 F ATOM 21611 CE2 TYR F 445 47101 42987-13498 1006102 F ATOM 21527 CG2 VALF435 51498 40748 -9863 1006076 F ATOM 21612 CZ TYR F 445 47503 41734-13058 1006102 F

ATOM 21528 C VALF435 5200637138-10935 1006942 F ATOM 21613 OH TYR F 445 46547 40770 -12799 1006102 F

ATOM 21529 O VALF435 5117236785-11768 1007001 F ATOM 21614 C TYRF445 51931 45931 -15453 1007665 F ATOM 21530 N PHEF436 5262436294-10106 1004795 F ATOM 21615 O TYR F 445 53099 45808-15074 1007951 F

ATOM 21531 CA PHEF436 52352 34861-10128 1004415 F ATOM 21616 N THR F 446 51473 47034-16040 10011499 F

ATOM 21532 CB PHE F 436 53652 34070-10087 1008769 F ATOM 21617 CA THR F 446 52358 48153-16361 10012197 F

ATOM 21533 CG PHE F 436 54526 34289-11280 1006246 F ATOM 21618 CB THR F 446 52349 48402 -17880 1008906 F ATOM 21534 CDl PHE F 436 5544035335-11308 1006246 F ATOM 21619 OGl THR F 446 51005 48663-18302 1007721 F ATOM 21535 CD2PHEF436 54435 33444-12382 1006246 F ATOM 21620 CG2THRF446 52863 47194-18631 1007721 F ATOM 21536 CEl PHE F 436 56261 35533-12423 1006246 F ATOM 21621 C THR F 446 52114 49511-15692 0013177 F ATOM 21537 CE2PHEF436 55248 33632 13502 1006246 F ATOM 21622 O THR F 446 51519 49613 -14617 0013544 F

ATOM 21538 CZ PHE F 436 5616434677-13524 1006246 F ATOM 21623 N CYS F 447 52624 50534 16384 0013887 F

ATOM 21539 C PHEF436 5147834472 -8950 1005198 F ATOM 21624 CA CYS F 447 52564 51965-16060 10013985 F

ATOM 21540 O PHEF436 51848 34669 -7794 1005136 F ATOM 21625 C CYS F 447 53246 52526 -14812 10013988 F ATOM 21541 N HISF437 50310 33924 -9253 1004608 F ATOM 21626 O CYS F 447 53236 51929-13735 10013674 F

ATOM 21542 CA HISF437 49373 33511 -8221 1004715 F ATOM 21627 CB CYS F 447 51 113 52475-16122 10018364 F

ATOM 21543 CB HIS F 437 48509 34699 -7797 1009762 F ATOM 21628 SG CYS F 447 49916 51707-14988 10016917 F

ATOM 21544 CG HIS F437 4752734372 -6717 1007399 F ATOM 21629 N SER F 448 53845 53700 -15001 10020084 F

ATOM 21545 CD2 HIS F 437 46212 34053 -6774 1007399 F ATOM 21630 CA SER F 448 54551 54424-13951 10020084 F

ATOM 21546 NDl HIS F 437 4788434292 -5388 1007399 F ATOM 21631 CB SER F 448 56052 54461 -14246 10020084 F

ATOM 21547 CEl HIS F 437 4683033937 -4674 1007399 F ATOM 21632 OG SER F 448 56587 53152 -14332 10020084 F

ATOM 21548 NE2 HIS F 437 45803 33785 -5491 1007399 F ATOM 21633 C SER F 448 54000 55846 -13871 10020084 F

ATOM 21549 C HIS F 437 48484 32395 -8764 1005146 F ATOM 21634 O SER F 448 52855 56089 -14260 10020084 F

ATOM 21550 O HISF437 48359 32242 -9976 1005368 F ATOM 21635 N GLU F 449 54817 56784 -13392 10018803 F

ATOM 21551 N ASP F 438 47868 31616 -7876 1005512 F ATOM 21636 CA GLU F 449 54385 58173-13229 10018803 F

ATOM 21552 CA ASPF438 4699730520 -8294 1005703 F ATOM 21637 CB GLU F 449 53741 58710-14516 10013046 F

ATOM 21553 CB ASPF438 4639529831 -7069 10010774 F ATOM 21638 CG GLU F 449 54729 59170-15572 10013046 F

ATOM 21554 CG ASP F 438 4732628783 -6484 1007870 F ATOM 21639 CD GLU F 449 55842 58173-15790 10013046 F ATOM 21555 ODl ASP F 438 48554 28876 -6728 1007870 F ATOM 21640 OEl GLU F 449 55535 56994-16065 10013046 F ATOM 21556 OD2 ASP F 438 46831 27875 5782 1007870 F ATOM 21641 OE2 GLU F 449 57023 58569-15683 10013046 F

ATOM 21557 C ASP F 438 45908 30985 -9256 1005837 F ATOM 21642 C GLU F 449 53353 58167-12110 10018803 F

ATOM 21558 O ASPF438 45665 30357-10284 1006193 F ATOM 21643 O GLU F 449 53357 59021 -11227 10018803 F

ATOM 21559 N THR F 439 4523832077 8922 1009175 F ATOM 21644 N GLY F 450 52481 57169-12164 1007805 F ATOM 21560 CA THR F 439 44238 32628 -9818 1008910 F ATOM 21645 CA GLY F 450 51427 56996 11 187 1007805 F

ATOM 21561 CB THRF439 43315 33578 -9061 1007977 F ATOM 21646 C GLY F 450 50275 56380 -11947 1007805 F ATOM 21562 OGl THR F439 44081 34669 8544 1006558 F ATOM 21647 O GLY F 450 49154 56302-11454 1007805 F ATOM 21563 CG2THRF439 42666 32850 -7891 1006558 F ATOM 21648 N CYSF451 50573 55938-13164 10018390 F

ATOM 21564 C THR F 439 45158 33389-10772 1009487 F ATOM 21649 CA CYS F 451 49577 55342-14039 10018390 F

ATOM 21565 O THR F 439 4619433887-10346 1009521 F ATOM 21650 CB CYS F 451 48975 54098-13406 10016707 F

ATOM 21566 N LEUF440 44813 33477-12049 10010040 F ATOM 21651 SG CYS F 451 50165 52744 -13266 10016707 F

ATOM 21567 CA LEUF440 4568434143-13027 10010242 F ATOM 21652 C CYS F 451 48480 56348-14290 10018390 F

ATOM 21568 CB LEUF440 45713 35686-12840 1009216 F ATOM 21653 O CYS F 451 47311 56013-14006 10018390 F

ATOM 21569 CG LEUF440 4616436656-11711 1007216 F ATOM 21654 OXT CYS F 451 48813 57454-14763 10013944 ATOM 21570 CDl LEU F 440 45210 36541 -10553 1007216 F ATOM 21571 CD2LEUF440 47603 36446-11265 1007216 F ATOM 21655 OH2TIPA452 -25070 -37082 29874 1002629 A

ATOM 21572 C LEUF440 47115 33589-13002 10011237 F ATOM 21656 OH2TIPA453 -12398 -7529 28666 1005013 A

ATOM 21573 O LEU F 440 48021 34229-12480 10011059 F ATOM 21657 OH2 TIP A 454 -9057-11779 29287 1004325 A

ATOM 21574 N GLU F 441 4731332403-13580 1007686 F ATOM 21658 OH2TIPA455 -5254 11 199 15730 1005168 A ATOM 21575 CA GLUF441 48629 31748-13620 1007686 F ATOM 21659 OH2 TIP A 456 -32698-22663 13953 1006628 A

ATOM 21576 CB GLU F 441 4871630805-14821 10019759 F ATOM 21660 OH2 TIP A 457 -18641-27224 16840 1005661 A ATOM 21577 CG GLU F 441 4776029627-14745 10012095 F ATOM 21661 OH2TIP A 458 -25885 -27088 20474 1005171 A ATOM 21578 CD GLU F 441 4798528623 15861 10012095 F ATOM 21662 OH2TIPA459 -3550 -9452 11111 1003725 A ATOM 21579 OEl GLU F 441 47914 29020-17046 10012095 F ATOM 21663 OH2 TIP A 460 0719 11029 13512 1004851 A ATOM 21580 OE2 GLU F 441 48236 27437 -15552 10012095 F ATOM 21664 OH2TIPA461 -19884 -5459 18116 I 005288 A

ATOM 21581 C GLU F 441 49821 32707-13637 1007686 F ATOM 21665 OH2 TIP A 462 -20875 -28974 41287 1004476 A

ATOM 21582 O GLU F 441 50799 32497-12925 1007686 F ATOM 21666 OH2 TIP A 463 -6264-10599 28617 1004954 A

ATOM 21583 N ALA F 442 49738 33755-14448 1008016 F ATOM 21667 OH2 TIP A 464 -15397-15617 18480 1005238 A ATOM 21584 CA ALAF442 50809 34738-14517 1007838 F ATOM 21668 OH2 TIP A 465 -11604-32604 17813 1005515 A ATOM 21585 CB ALA F 442 5207434098-15063 1003761 F ATOM 21669 OH2 TIP A 466 -4100 -8096 13946 1005237 A ATOM 21586 C ALA F 442 503S6 35910-15392 1007437 F ATOM 21670 OH2 TIP A 467 -20351 8083 12958 1003574 A

ATOM 21587 O ALAF442 5031435780-16612 1007178 F ATOM 21671 OH2 TIP B 452 5473 25059 67902 1002629 B

ATOM 21588 N GLN F 443 50099 37050-14768 1008032 F ATOM 21672 OH2 TIP B 453 -3879 10049 40726 1005013 B ATOM 21589 CA GLNF443 49681 38241 -15500 1008360 F ATOM 21673 OH2 TIP B 454 2008 9463 42344 1004325 B ATOM 21590 CB GLN F 443 48339 38746-14986 1009076 F ATOM 21674 OH2 TIP B 455 -14450 -8279 30517 1005168 B ATOM 21591 CG GLN F 443 4714938161 15704 1007399 F ATOM 21675 OH2 TIP B 456 -13917 12739 68373 1006628 B ATOM 21592 CD GLN F 443 4589939007 -15511 1007399 F ATOM 21676 OH2 TIP B 457 -0165 8079 64205 1005661 B ATOM 21593 OEl GLN F 443 4592040231-15723 1007399 F ATOM 21677 OH2 TIP B 458 -5764 16338 64985 1005171 E 65251/C766

ATOM 21678 OH2TIPB459 -2589 -886747353 1003725 B ATOM 21763 C6 NAG A 468 29113-40845 33163 1005751 A ATOM 21679 OH2 TIP B 460 2297 -9443 45553 1004851 B ATOM 21764 06 NAG A 468 -27873 -41278 32618 1005751 A

ATOM 21680 OH2 TIP B 461 -14112 565447666 1005288 B ATOM 21765 Cl NAG A 469 1059 -35497 35906 10011281 A

ATOM 21681 OH2TIPB462 752729221 53940 1004476 B ATOM 21766 C2 NAG A 469 -0515-34629 37094 10011281 A

ATOM 21682 OH2TIPB463 2171 703840480 1004954 B ATOM 21767 N2 NAG A 469 -0787 -33224 36829 10011281 A

ATOM 21683 OH2TIPB464 -4585 5110 53365 1005238 B ATOM 21768 C7 NAG A 469 0219-32360 36668 10011281 A

ATOM 21684 OH2 TIP B 465 8911 6284 64949 1005515 B ATOM 21769 07 NAG A 469 0668-31669 37588 10011281 A

ATOM 21685 OH2TIPB466 -3027 -630444890 1005237 B ATOM 21770 C8 NAG A 469 0830 -32253 35275 10011281 A

ATOM 21686 OH2 TIP B 467 -24001 -1506 39948 1003574 B ATOM 21771 C3 NAG A 469 1010-34773 37356 10011281 A

ATOM 21687 OH2TIPC452 402424034-10748 1002629 C ATOM 21772 03 NAG A 469 1328 -34309 38663 10011281 A ATOM 21688 OH2 TIP C 453 -3754 10576 18128 1005013 C ATOM 21773 C4 NAG A 469 1493 -36204 37197 10011281 A

ATOM 21689 OH2 TIP C 454 1043 9077 15439 1004325 C ATOM 21774 04 NAG A 469 2910-36252 37294 10011281 A

ATOM 21690 OH2TIPC455 -3568 13031 40887 1005168 C ATOM 21775 C5 NAG A 469 1039 -36663 35828 10011281 A

ATOM 21691 OH2TIPC456 -2771 37525 7450 1006628 C ATOM 21776 05 NAG A 469 -0391 -36769 35826 10011281 A

ATOM 21692 OH2TIPC457 9221 27781 6164 1005661 C ATOM 21777 C6 NAG A 469 1593 -38002 35402 10011281 A

ATOM 21693 OH2TIPC458 0751 29872 1818 1005171 C ATOM 21778 06 NAG A 469 1174-38312 34081 10011281 A

ATOM 21694 OH2TIPC459 10622 18769 28680 1003725 C ATOM 21779 Cl NAG A 470 -50698-29175 43848 10015357

ATOM 21695 OH2TIPC460 14203 14549 28076 1004851 _f

ATOM 21696 OH2 TIP C 461 -577222658 22124 1005288 C ATOM 21780 C2 NAG A 470 -50893 -27722 43400 10015357

ATOM 21697 OH2TIPC462 -2831 10753 -7603 1004476 ( L-". A

ATOM 21698 OH2TIPC463 2860 7524 17778 1004954 C ATOM 21781 N2 NAG A 470 -50373 -27475 42069 10015357 ATOM 21699 OH2 TIP C 464 400721061 16717 1005238 p A

ATOM 21700 OH2 TIP C 465 15934 23391 3911 1005515 C ATOM 21782 C7 NAG A 470 -50653 -26323 41462 10015357

ATOM 21701 OH2TIPC466 8071 17151 28026 1005237 (-> A

ATOM 21702 OH2 TIP C 467 -1143924219 35327 1003574 C ATOM 21783 07 NAG A 470 -51796-25996 41147 10015357

ATOM 21703 OH2 TIP D 452 4526829003 -67249 1002629 A

ATOM 21704 OH2TIPD453 56797 13362 -40946 1005013 D ATOM 21784 C8 NAG A 470 -49495 -25380 41181 10015357

ATOM 21705 OH2TIPD454 50903 13373-42094 1004325 D A

ATOM 21706 OH2TIPD455 67726 -5016-32013 1005168 D ATOM 21785 C3 NAG A 470 -50235 -26804 44418 10015357

ATOM 21707 OH2 TIP D 456 63736 15430 -69676 1006628 L) A

ATOM 21708 OH2TIPD457 50223 11768-64145 1005661 D ATOM 21786 03 NAG A 470 -50446-25450 44040 10015357

ATOM 21709 OH2TIPD458 56193 20359-66232 1005171 D ATOM 21710 OH2 TIP D459 54232 -5287-47334 1003725 D ATOM 21787 C4 NAG A 470 -50838 -27066 45809 10015357

ATOM 21711 OH2 TIP D 460 49094 -5727-45008 1004851 D

ATOM 21712 OH2 TIP D 461 66287 8885-49223 1005288 D ATOM 21788 04 NAG A 470 -50102-26345 46788 10015357

ATOM 21713 OH2TIPD462 45723 33240-52765 1004476 A

ATOM 21714 OH2TIPD463 50808 10801 -40404 1004954 D ATOM 21789 C5 NAG A 470 -50825 -28568 46167 10015357

ATOM 21715 OH2 TIP D 464 55928 8879-53601 1005238 A

ATOM 21716 OH2TIPD465 41439 10938-63575 1005515 D ATOM 21790 05 NAG A 470 51386-29364 45092 10015357

ATOM 21717 OH2 TIP D 466 54885 -2614 -45203 1005237 A

ATOM 21718 OH2 TIP D 467 76382 1303 -42824 1003574 D ATOM 21791 C6 NAG A 470 -51652-28856 47410 10015357

ATOM 21719 OH2 TIP E 452 78797 -34064 -33425 1002629 E A

ATOM 21720 OH2 TIP E 453 65806 -4337 -29986 1005013 E ATOM 21792 06 NAG A 470 -51272-30083 48015 10015357

ATOM 21721 OH2TIPE454 62920 -8466-30344 1004325 E A

ATOM 21722 OH2TIPE455 61459 14258-16519 1005168 E ATOM 21793 Cl NAG B 468 3753 28506 68128 005679 B

ATOM 21723 OH2TIPE456 88278-19664-17874 1006628 E ATOM 21794 C2 NAG B 468 2852 27733 69103 005679 B

ATOM 21724 OH2 TIP E 457 73931-24037-19137 1005661 E ATOM 21795 N2 NAG B 468 159627424 68443 005679 B

ATOM 21725 OH2 TIP E 458 80667 -23704 -23668 1005171 E ATOM 21796 C7 NAG B 468 133626188 68022 005679 B

ATOM 21726 OH2 TIP E 459 59111 -6011 -11737 1003725 E ATOM 21797 07 NAG B 468 210725239 68181 005679 B

ATOM 21727 OH2 TIP E 460 54206 -7763 -12773 1004851 E ATOM 21798 C8 NAG B 468 0012 25967 67312 005679 B

ATOM 21728 OH2 TIP E 461 74734 -2013 -20732 1005288 E ATOM 21799 C3 NAG B 468 256628533 70387 005679 B

ATOM 21729 OH2 TIP E 462 72384 -24633 -43695 1004476 E ATOM 21800 03 NAG B 468 194727688 71338 005679 B

ATOM 21730 OH2 TIP E 463 60287 -7010-29381 1004954 E ATOM 21801 C4 NAG B 468 384929108 70983 005679 B

ATOM 21731 OH2TIPE464 70824-12289-20457 1005238 E ATOM 21802 04 NAG B 468 355429893 72142 005679 B

ATOM 21732 OH2 TIP E 465 67057 -29755 -19644 1005515 E ATOM 21803 C5 NAG B 468 451229944 69887 005679 B

ATOM 21733 OH2TIPE466 59372 -4764-14557 1005237 E ATOM 21804 05 NAG B 468 488729076 68799 005679 B

ATOM 21734 OH2TIPE467 75818 10774-14880 1003574 E ATOM 21805 C6 NAG B 468 575930676 70331 005679 B

ATOM 21735 OH2TIPF452 5560727153 11357 1002629 F ATOM 21806 06 NAG B 468 684029777 70538 005679 B

ATOM 21736 OH2TIPF453 59034 13968-18301 1005013 F ATOM 21807 Cl NAG B 469 23782 15210 53924 1008108 B

ATOM 21737 OH2 TIP F 454 55113 12363 -15078 1004325 F ATOM 21808 C2 NAG B 469 24226 15502 52450 1008108 B

ATOM 21738 OH2 TIP F 455 57188 16070-41291 1005168 F ATOM 21809 N2 NAG B 469 23101 15290 51556 1008108 B

ATOM 21739 OH2 TIP F 456 6070640941 -6962 1006628 F ATOM 21810 C7 NAG B 469 23222 14493 50495 1008108 B

ATOM 21740 OH2 TIP F 457 4895031550 -5348 1005661 F ATOM 21811 07 NAG B 469 23440 14918 49358 1008108 B

ATOM 21741 OH2TIPF458 58332 33171 -1901 1005171 F ATOM 21812 C8 NAG B 469 23078 12991 50726 1008108 B

ATOM 21742 OH2 TIP F 459 4414622790 -27160 1003725 F ATOM 21813 C3 NAG B 469 25410 14632 51953 1008108 B

ATOM 21743 OH2TIPF460 40375 19225-26540 1004851 F ATOM 21814 03 NAG B 469 25959 15190 50769 1008108 B ATOM 21744 OH2 TIP F 461 6154226045 -22682 1005288 F ATOM 21815 C4 NAG B 469 26488 14497 53024 1008108 B

ATOM 21745 OH2TIPF462 61287 14004 7585 1004476 F ATOM 21816 04 NAG B 469 27528 13627 52586 1008108 B

ATOM 21746 OH2TIPF463 53439 11452-17341 1004954 F ATOM 21817 C5 NAG B 469 25764 13926 54232 1008108 B

ATOM 21747 OH2 TIP F464 5437226132 -15089 1005238 F ATOM 21818 05 NAG B 469 24898 14922 54765 1008108 B

ATOM 21748 OH2TIPF465 4173227472 -1930 1005515 F ATOM 21819 C6 NAG B 469 26602 13458 55384 1008108 B

ATOM 21749 OH2 TIP F 466 4647621044 -26806 1005237 F ATOM 21820 06 NAG B 469 25849 13574 56587 1008108 B

ATOM 21750 OH2TIPF467 6579527507-36714 1003574 F ATOM 21821 Cl NAG B 470 -1316748108 64895 10012467 B

ATOM 21751 Cl NAG A 468 -28649-37315 32123 1005751 A ATOM 21822 C2 NAG B 470 -1439447327 64348 10012467 B

ATOM 21752 C2 NAGA468 -29297-37315 30736 1005751 A ATOM 21823 N2 NAG B 470 -1424545891 64540 10012467 B

ATOM 21753 N2 NAG A 468 29620 35952 30358 1005751 A ATOM 21824 C7 NAG B 470 -15223 45059 64182 10012467 B

ATOM 21754 C7 NAG A 468 -28837 -35282 29514 1005751 A ATOM 21825 07 NAG B 470 -16407 45282 64424 10012467 B ATOM 21755 07 NAGA468 -27703-35648 29218 1005751 A ATOM 21826 C8 NAG B 470 -14838 43792 63434 10012467 B

ATOM 21756 C8 NAG A 468 -29399-34012 28911 1005751 A ATOM 21827 C3 NAG B 470 -1466747634 62862 10012467 B

ATOM 21757 C3 NAG A 468 -30566-38193 30755 1005751 A ATOM 21828 03 NAG B 470 -1596747162 62525 10012467 B

ATOM 21758 03 NAG A 468 -31169-38233 29470 1005751 A ATOM 21829 C4 NAG B 470 -14572 49149 62563 10012467 B

ATOM 21759 C4 NAG A 468 -30202-39615 31206 1005751 A ATOM 21830 04 NAG B 470 -1457249372 61159 10012467 B

ATOM 2176004 NAG A 468 -31367 -40456 31251 1005751 A ATOM 21831 C5 NAG B 470 -13286 49712 63160 10012467 B

ATOM 21761 C5 NAG A 468 -29536-39503 32590 1005751 A ATOM 21832 05 NAG B 470 -1328249499 64581 10012467 B

ATOM 21762 05 NAG A 468 -28350-38662 32511 1005751 A ATOM 21833 C6 NAG B 470 -13069 51184 62915 10012467 B 65251/C766

ATOM 21834 06 NAG B 470 -11 772 51 413 62 386 1 00124 67 B ATOM 21919 Cl NAG E 468 82 012 -33 741 -35 940 1 0054 79 E

ATOM 21835 Cl NAG C 468 0704 24 698 -12 830 1 00 79 12 C ATOM 21920 C2 NAG E 468 82 857 -33 812 -34660 1 00 54 79 E

ATOM 21836 C2 NAG C 468 0 684 26 115 -12 213 1 00 79 12 C ATOM 21921 N2 NAG E 468 83 299 -32 477 -34289 1 00 54 79 E

ATOM 21837 N2 NAG C 468 -0292 26 174 -11 148 1 0079 12 C ATOM 21922 C7 NAG E 468 82 646 -31 766 -33 360 1 005479 E

ATOM 21838 C7 NAG C 468 0 114 26341 -9 897 1 00 79 12 C ATOM 21923 07 NAG E 468 81 591 -32 129 -32 818 1 00 54 79 E

ATOM 21839 07 NAG C 468 1 225 25 977 -9 499 00 79 12 C ATOM 21924 C8 NAG E 468 83 266 -30433 -32 978 1 00 54 79 E

ATOM 21840 C8 NAG C 468 -0 862 27016 -8 947 00 79 12 C ATOM 21925 C3 NAG E 468 84 065 -34751 -34 839 1 00 54 79 E

ATOM 21841 C3 NAG C 468 0355 27206 -13 243 1 00 79 12 C ATOM 21926 03 NAG E 468 84 721 -34 920 -33 595 1 00 54 79 E

ATOM 21842 03 NAG C 468 0561 28485 -12 650 1 00 79 12 C ATOM 21927 C4 NAG E 468 83 593 -36 115 -35 332 1 00 54 79 E

ATOM 21843 C4 NAG C 468 1 240 27 054 -14 490 1 00 79 12 C ATOM 21928 04 NAG E 468 84 702 -37005 -35 524 1 00 54 79 E

ATOM 21844 04 NAG C 468 0872 28001 -15 493 1 00 79 12 C ATOM 21929 C5 NAG E 468 82 812 35 910 -36 632 1 00 54 79 E

ATOM 21845 C5 NAG C 468 1 088 25 631 -15 022 1 00 79 12 C ATOM 21930 05 NAG E 468 81 662 -35 063 -36387 1 00 54 79 E

ATOM 21846 05 NAG C 468 1 523 24687 -14 017 1 00 79 12 C ATOM 21931 C6 NAG E 468 82295 -37212 -37223 1 00 54 79 E

ATOM 21847 C6 NAG C 468 1 926 25 388 -16 256 1 00 79 12 C ATOM 21932 06 NAG E 468 81 254 -37772 -36431 1 00 54 79 E

ATOM 21848 06 NAG C 468 3 113 24677 -15 937 1 0079 12 C ATOM 21933 Cl NAG E 469 54 129 -32 392 -35969 1 00122 52 E

ATOM 21849 Cl NAG C 469 17 518 4 112 4003 1 00140 88 C ATOM 21934 C2 NAG E 469 53 443 -31 462 -37018 1 00122 52 E

ATOM 21850 C2 NAG C 469 17 062 2 638 -3 820 1 00140 88 C ATOM 21935 N2 NAG E 469 53 780 -30075 -36 737 1 00122 52 E

ATOM 21851 N2 NAG C 469 15 977 2 595 -2 851 00140 88 C ATOM 21936 C7 NAG E 469 52 843 -29208 -36 344 1 00122 52 E

ATOM 21852 C7 NAG C 469 16 162 2 078 -1 635 1 0014088 C ATOM 21937 07 NAG E 469 52274 -28434 -37 121 1 0012252 E

ATOM 21853 07 NAG C 469 15 642 1 019 -1 273 00140 88 C ATOM 21938 C8 NAG E 469 52 483 -29 189 -34 862 1 00122 52 E

ATOM 21854 C8 NAG C 469 17 048 2 854 -0 666 1 00140 88 C ATOM 21939 C3 NAG E 469 51 904 -31 615 -37 041 1 00122 52 E

ATOM 21855 C3 NAG C 469 18203 1 702 -3 349 1 00140 88 C ATOM 21940 03 NAG E 469 51 354 -30948 -38 169 1 00122 52 E

ATOM 21856 03 NAG C 469 17 810 0 342 -3 488 00140 88 C ATOM 21941 C4 NAG E 469 51 506 -33 076 -37 077 1 00122 52 E

ATOM 21857 C4 NAG C 469 19487 1 941 -4 137 1 00140 88 C ATOM 21942 04 NAG E 469 50091 -33 194 -37 048 1 00122 52 E

ATOM 21858 04 NAG C 469 20 544 1 166 -3 583 00140 88 C ATOM 21943 C5 NAG E 469 52 122 -33 727 -35 857 1 00122 52 E

ATOM 21859 C5 NAG C 469 19818 3 427 4055 1 0014088 C ATOM 21944 05 NAG E 469 53 550 -33 708 -35 985 1 00122 52 E

ATOM 21860 05 NAG C 469 18 774 4 180 -4 697 00140 88 C ATOM 21945 C6 NAG E 469 51 731 -35 169 -35 685 1 00122 52 E

ATOM 21861 C6 NAG C 469 21 125 3 808 -4 720 1 00140 88 C ATOM 21946 06 NAG E 469 52 835 -35 918 -35 201 1 00122 52 E

ATOM 21862 06 NAG C 469 21 569 5 084 -4278 00140 88 C ATOM 21947 Cl NAG E 470 102 230 -25 224 -50276 1 0015803

ATOM 21863 Cl NAG C 470 -24264 27981 -20 130 1 0014799 C E

ATOM 21864 C2 NAG C 470 -25 086 28 340 -18 862 1 00147 99 C ATOM 21948 C2 NAG E 470 102 652 -23 930 -49 540 1 00158 03

ATOM 21865 N2 NAG C 470 -24 216 28 803 17 793 1 0014799 C E

ATOM 21866 C7 NAG C 470 -24 695 28 982 16 561 1 0014799 C ATOM 21949 N2 NAG E 470 102 132 -23 908 -48 183 1 00158 03

ATOM 21867 07 NAG C 470 -25 498 29 873 -16277 1 0014799 C E

ATOM 21868 C8 NAG C 470 -24221 28 022 15 479 1 0014799 C ATOM 21950 C7 NAG E 470 102 473 -22 929 -47345 1 0015803

ATOM 21869 C3 NAG C 470 -25 945 27 163 -18 365 1 0014799 C E

ATOM 21870 03 NAG C 470 -26886 27639 -17409 1 0014799 C ATOM 21951 07 NAG E 470 103 612 -22 800 -46 899 1 0015803

ATOM 21871 C4 NAG C 470 26698 26496 -19 521 1 00147 99 C E

ATOM 21872 04 NAG C 470 -27326 25 307 -19 064 1 0014799 C ATOM 21952 C8 NAG E 470 101 390 -21 938 -46943 1 00158 03

ATOM 21873 C5 NAG C 470 -25 728 26 159 -20 652 1 00147 99 C E

ATOM 21874 05 NAG C 470 -25097 27367 -21 127 1 0014799 C ATOM 21953 C3 NAG E 470 102 192 -22680 -50305 1 0015803

ATOM 21875 C6 NAG C 470 -26412 25 504 -21 836 1 00147 99 C E

ATOM 21876 06 NAG C 470 -26 152 24 109 -21 870 1 00147 99 C ATOM 21954 03 NAG E 470 102 787 -21 525 _^ 49 724 1 00158 03

ATOM 21877 Cl NAG D 468 47479 32 389 -67 588 1 00 49 52 D E

ATOM 21878 C2 NAG D 468 48 138 31 547 -68 690 1 00 49 52 D ATOM 21955 C4 NAG E 470 102 593 -22 771 -51 783 1 00158 03

ATOM 21879 N2 NAG D 468 49424 31 075 -68 205 1 00 49 52 D E

ATOM 21880 C7 NAG D 468 49 547 29 878 -67 633 1 00 49 52 D ATOM 21956 04 NAG E 470 102 025 -21 687 -52 505 1 00158 03

ATOM 21881 07 NAG D 468 48652 29 036 -67 630 1 0049 52 D E

ATOM 21882 C8 NAG D 468 50 877 29 567 -66 964 1 00 49 52 D ATOM 21957 C5 NAG E 470 102 106 -24093 52 378 1 00158 03

ATOM 21883 C3 NAG D 468 48 352 32 356 -69 989 1 0049 52 D E

ATOM 21884 03 NAG D 468 48 780 31 508 -71 039 1 00 49 52 D ATOM 21958 05 NAG E 470 102 666 -25 199 -51 642 1 00158 03

ATOM 21885 C4 NAG D 468 47074 33 070 -70407 1 004952 D E

ATOM 21886 04 NAG D 468 47299 33 841 -71 596 1 00 49 52 D ATOM 21959 C6 NAG E 470 102 516 -24265 -53 823 1 00158 03

ATOM 21887 C5 NAG D 468 46694 33 956 -69 231 1 00 49 52 D E

ATOM 21888 05 NAG D 468 46358 33 119 -68 101 1 00 49 52 D ATOM 21960 06 NAG E 470 102 339 -25 608 -54242 1 00158 03

ATOM 21889 C6 NAG D 468 45 525 34 889 -69 499 1 0049 52 D E

ATOM 21890 06 NAG D 468 44276 34 223 -69 383 1 00 49 52 D ATOM 21961 Cl NAG F 468 59 178 27 704 12 879 00 90 14 F

ATOM 21891 Cl NAG D 469 28 308 20 674 -50 916 1 00 9643 D ATOM 21962 C2 NAG F 468 59 308 29 123 12 317 0090 14 F

ATOM 21892 C2 NAG D 469 27 862 21 124 -49490 1 009643 D ATOM 21963 N2 NAG F 468 60 050 29 106 11 073 00 90 14 F

ATOM 21893 N2 NAG D 469 28925 20 827 -48 547 1 00 9643 D ATOM 21964 C7 NAG F 468 59 414 29309 9 927 1 00 90 14 F

ATOM 21894 C7 NAG D 469 28 802 19 791 -47 714 1 00 9643 D ATOM 21965 07 NAG F 468 58 190 29211 9 815 1 00 90 14 F

ATOM 21895 07 NAG D 469 28 198 19 860 -46 639 1 00 9643 D ATOM 21966 C8 NAG F 468 60 265 29 678 8 725 1 0090 14 F

ATOM 21896 C8 NAG D 469 29419 18470 -48 142 1 009643 D ATOM 21967 C3 NAG F 468 60006 30022 13 346 0090 14 F

ATOM 21897 C3 NAG D 469 26 588 20 432 -48 951 1 00 9643 D ATOM 21968 03 NAG F 468 60 083 31 353 12 849 00 90 14 F

ATOM 21898 03 NAG D 469 26 006 21 222 -47 920 1 009643 D ATOM 21969 C4 NAG F 468 59 219 29 987 14 668 00 90 14 F

ATOM 21899 C4 NAG D 469 25 543 20 143 -50 023 1 009643 D ATOM 21970 04 NAG F 468 59 876 30764 15 668 00 90 14 F

ATOM 21900 04 NAG D 469 24564 19254 -49495 1 009643 D ATOM 21971 C5 NAG F 468 59068 28 529 15 137 0090 14 F

ATOM 21901 C5 NAG D 469 26242 19 508 -51 227 1 009643 D ATOM 21972 05 NAG F 468 58 433 27733 14 106 00 90 14 F

ATOM 21902 05 NAG D 469 27 179 20449 -51 771 1 009643 D ATOM 21973 C6 NAG F 468 58201 28407 16 374 00 90 14 F

ATOM 21903 C6 NAG D 469 25 310 19 090 -52 357 1 009643 D ATOM 21974 06 NAG F 468 57 181 27432 16 189 00 90 14 F

ATOM 21904 06 NAG D 469 25 786 19 540 -53 618 1 009643 D ATOM 21975 Cl NAG F 469 40547 8 020 5 881 1 00128 78 F

ATOM 21905 Cl NAG D 470 65 895 50 746 -66 573 1 00151 66 D ATOM 21976 C2 NAG F 469 40967 6 526 5 740 1 00128 78 F

ATOM 21906 C2 NAG D 470 67 062 49 973 -65 912 1 00151 66 D ATOM 21977 N2 NAG F 469 41 939 6409 4 660 1 00128 78 F

ATOM 21907 N2 NAG D 470 66 880 48 539 -66090 1 00151 66 D ATOM 21978 C7 NAG F 469 41 607 5 882 3479 1 0012878 F

ATOM 21908 C7 NAG D 470 67 821 47 676 -65 706 1 00151 66 D ATOM 21979 07 NAG F 469 42 038 4 795 3 095 1 00128 78 F

ATOM 21909 07 NAG D 470 68 948 47 650 -66202 1 00151 66 D ATOM 21980 C8 NAG F 469 40 675 6 679 2 574 1 00128 78 F

ATOM 21910 C8 NAG D 470 67459 46 688 -64 607 1 00151 66 D ATOM 21981 C3 NAG F 469 39 785 5 557 5 475 1 00128 78 F

ATOM 21911 C3 NAG D 470 67 170 50311 -64411 1 00151 66 D ATOM 21982 03 NAG F 469 40 185 4220 5 744 1 0012878 F

ATOM 21912 03 NAG D 470 68 399 49 806 -63 901 1 00151 66 D ATOM 21983 C4 NAG F 469 38 575 5 893 6 333 1 00128 78 F

ATOM 21913 C4 NAG D 470 67 100 51 834 -64 164 1 00151 66 D ATOM 21984 04 NAG F 469 37475 5 068 5 974 1 00128 78 F

ATOM 21914 04 NAG D 470 66 968 52 092 -62 773 1 00151 66 D ATOM 21985 C5 NAG F 469 38243 7 351 6 094 1 00128 78 F

ATOM 21915 C5 NAG D 470 65 903 52430 -64908 1 00151 66 D ATOM 21986 05 NAG F 469 39 313 8 160 6 614 1 00128 78 F

ATOM 21916 05 NAG D 470 66 023 52 147 -66 314 1 00151 66 D ATOM 21987 C6 NAG F 469 36958 7 795 6 763 1 00128 78 F

ATOM 21917 C6 NAG D 470 65 748 53 927 -64 754 1 00151 66 D ATOM 21988 06 NAG F 469 36 152 8 549 5 869 1 00128 78 F

ATOM 21918 06 NAG D 470 64432 54335 -65 100 1 00151 66 D ATOM 21989 Cl NAG F 470 84705 30 138 16795 0015052 F 65251/C766

ATOM 21990 C2 NAG F 470 85213 30232 15342 10015052 F ATOM 21997 C4 NAG F 470 8709428703 16010 10015052 F

ATOM 21991 N2 NAG F 470 84113 30447 14415 10015052 F ATOM 21998 04 NAG F 470 8771627456 15741 10015052 F

ATOM 21992 C7 NAG F 470 84352 30588 13113 10015052 F ATOM 21999 C5 NAG F 470 8649728689 17426 10015052 F

ATOM 21993 07 NAG F 470 8512731432 12660 10015052 F ATOM 22000 05 NAG F 470 85813 29934 17686 10015052 F

ATOM 21994 C8 NAG F 470 8363029641 12170 10015052 F ATOM 22001 C6 NAG F 470 87532 28498 18520 10015052 F

ATOM 21995 C3 NAGF470 8599028963 14974 10015052 F ATOM 22002 06 NAGF470 8724027350 19308 10015052 F

ATOM 21996 03 NAGF470 8656729111 13684 10015052 F END