Title:
METHODS OF DETECTING INFLUENZA VIRUS
Document Type and Number:
WIPO Patent Application WO/2014/143864
Kind Code:
A3
Abstract:
Provided herein is a method of detecting the presence of influenza virus in a sample while minimizing false positives due to presence of one or more other pathogens in the sample, the method including measuring the enzymatic activity of neuraminidase (NA) in the sample under one or more differentiating conditions selected from the group consisting of pH, binding to anti-NanA antibody, size exclusion, hemagglutinin (HA) binding, chemical inhibition, and combinations thereof.
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Inventors:
WEISS ALISON (US)
GALLEGOS VILLALOBOS KAREN MELISSA (US)
RALPH DAVID (US)
GALLEGOS VILLALOBOS KAREN MELISSA (US)
RALPH DAVID (US)
Application Number:
PCT/US2014/028018
Publication Date:
November 06, 2014
Filing Date:
March 14, 2014
Export Citation:
Assignee:
UNIV CINCINNATI (US)
MICROBECAPTURE LLC (US)
WEISS ALISON (US)
GALLEGOS VILLALOBOS KAREN MELISSA (US)
RALPH DAVID (US)
MICROBECAPTURE LLC (US)
WEISS ALISON (US)
GALLEGOS VILLALOBOS KAREN MELISSA (US)
RALPH DAVID (US)
International Classes:
C12Q1/70; C07H17/02; C12Q1/34; C12Q1/66
Domestic Patent References:
| WO2011143262A2 | 2011-11-17 |
Foreign References:
| US7081352B2 | 2006-07-25 | |||
| US20110189655A1 | 2011-08-04 | |||
| US4029763A | 1977-06-14 |
Other References:
HOGLUND ET AL.: "Effect of Parainfluenza-3 Virus Neuraminidase on the Structure of the Gel Phase of Bovine Nasal Secretion", INFECT. IMMUN., vol. 10, no. 4, 24 June 1974 (1974-06-24), pages 877
FUKUI ET AL.: "NEURAMINIDASE ACTIVITY IN SOME BACTERIA FROM THE HUMAN MOUTH", ADS ORAL BID.;, vol. 16, 1971, pages 1361 - 1365
FUKUI ET AL.: "NEURAMINIDASE ACTIVITY IN SOME BACTERIA FROM THE HUMAN MOUTH", ADS ORAL BID.;, vol. 16, 1971, pages 1361 - 1365
Attorney, Agent or Firm:
LIVINGSTON, Jennifer L. et al. (255 East Fifth StreetSuite 190, Cincinnati OH, US)
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