Title:
METHODS FOR DETECTION OF DISEASE-ASSOCIATED ANTIBODIES IN URINE
Document Type and Number:
WIPO Patent Application WO2003000845
Kind Code:
A3
Abstract:
The present invention provides methods and diagnostic kits for the detection of disease-specific antibodies in urine containing sample. The present invention is also directed toward methods for determining that a patient suffers from a disorder characterized by aberrant expression of a naturally occurring gene. Methods for monitoring the status of a disorder in a patient characterized by aberrant expression of a naturally occurring gene are also provided.
Inventors:
KNUTH ALEXANDER
JAGER ELKE
JAGER DIRK
JAGER ELKE
JAGER DIRK
Application Number:
PCT/US2002/019478
Publication Date:
August 14, 2003
Filing Date:
June 21, 2002
Export Citation:
Assignee:
LUDWIG INST CANCER RES (US)
International Classes:
G01N33/574; G01N33/68; (IPC1-7): G01N33/53; G01N33/566; G01N33/574
Other References:
MEID F.H. ET AL.: "The use of telomerase activity for the detection of prostatic cancer cells after prostatic massage", JOURNAL OF UROLOGY, vol. 165, May 2001 (2001-05-01), pages 1802 - 1805, XP002961128
CHEN Y.-T. ET AL.: "A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening", PROC. NATL. ACAD. SCI. USA, vol. 94, March 1997 (1997-03-01), pages 1914 - 1918, XP002924084
STOCKERT E. ET AL.: "A survey of the humoral immune response of cancer patients to a panel of human tumor antigens", J. EXP. MED., vol. 187, no. 8, 20 April 1998 (1998-04-20), pages 1349 - 1354, XP000867818
CHEN Y.-T. ET AL.: "A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening", PROC. NATL. ACAD. SCI. USA, vol. 94, March 1997 (1997-03-01), pages 1914 - 1918, XP002924084
STOCKERT E. ET AL.: "A survey of the humoral immune response of cancer patients to a panel of human tumor antigens", J. EXP. MED., vol. 187, no. 8, 20 April 1998 (1998-04-20), pages 1349 - 1354, XP000867818
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