Title:
METHODS AND DEVICES FOR POINT OF USE MIXING OF PHARMACEUTICAL FORMULATIONS
Document Type and Number:
WIPO Patent Application WO/2014/169081
Kind Code:
A3
Abstract:
Methods and devices for delivering variable amounts of a drug formulation directly from a drug delivery device without requiring point of use reconstitution as a separate mixing step are described herein. These methods and devices increase the convenience, speed and simplicity of administration of drug formulations. The devices mix two or more components in a constant mixing ratio effectively simultaneous to administration, and allow for variable doses while retaining the desired ratio of the components in each dose. The devices are particularly useful for administering drug formulations that are unstable at room temperature in liquid form. The methods described herein generally use conventional devices that have been modified to administer an unstable compound and provide acceptable storage stability. Typical devices include infusion sets, pump reservoirs, syringes, pens, vials and cartridges.
Inventors:
MICHEL GERARD (US)
FELDSTEIN ROBERT (US)
WILSON BRYAN (US)
GANEM JAKE (US)
FELDSTEIN ROBERT (US)
WILSON BRYAN (US)
GANEM JAKE (US)
Application Number:
PCT/US2014/033570
Publication Date:
May 07, 2015
Filing Date:
April 09, 2014
Export Citation:
Assignee:
BIODEL INC (US)
International Classes:
A61M5/14; A61J1/22; A61M5/32; B01F23/00
Domestic Patent References:
| WO1986003416A1 | 1986-06-19 | |||
| WO2003062519A1 | 2003-07-31 | |||
| WO2010149734A1 | 2010-12-29 | |||
| WO2012011909A1 | 2012-01-26 |
Foreign References:
| CA2256650C | 2006-04-11 |
Attorney, Agent or Firm:
PABST, Patrea (NESuite 32, Atlanta GA, US)
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