Title:
METHODS AND DEVICES FOR PREDICTING TREATMENT EFFICACY
Document Type and Number:
WIPO Patent Application WO/2011/135459
Kind Code:
A3
Abstract:
The present invention features methods, devices, and kits for predicting the sensitivity of a patient to a compound or medical treatment. The invention also features methods for identifying biomarkers, the expression of which correlates to treatment sensitivity or resistance within a patient population or subpopulation.
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Inventors:
KNUDSEN STEEN (DK)
Application Number:
PCT/IB2011/001405
Publication Date:
June 07, 2012
Filing Date:
April 29, 2011
Export Citation:
Assignee:
MEDICAL PROGNOSIS INST A S (DK)
KNUDSEN STEEN (DK)
KNUDSEN STEEN (DK)
International Classes:
C12Q1/68
Domestic Patent References:
| WO2008112283A2 | 2008-09-18 | |||
| WO2009080437A1 | 2009-07-02 |
Other References:
SYLVAIN PRADERVAND ET AL: "Concordance among digital gene expression, microarrays, and qPCR when measuring differential expression of microRNAs", BIOTECHNIQUES, vol. 48, no. 3, 1 March 2010 (2010-03-01), pages 219 - 222, XP055012457, ISSN: 0736-6205, DOI: 10.2144/000113367
SUNG-CHOU LI ET AL: "Intronic MicroRNA: Discovery and Biological Implications", DNA AND CELL BIOLOGY, MARY ANN LIEBERT, NEW YORK, NY, US, vol. 26, no. 4, 1 April 2007 (2007-04-01), pages 195 - 207, XP008124956, ISSN: 1044-5498
"SEQ ID NO 486 of EP2112235 disclosing has-miR-766", 31 October 2009 (2009-10-31), XP055012964, Retrieved from the Internet
FRIIS-HANSEN L ET AL: "1072 Mir-449 Inhibits Growth of Gastric Cancer Cells Partly By Inhibiting the Expression of Met and Amphiregulin", GASTROENTEROLOGY, ELSEVIER, PHILADELPHIA, PA, vol. 136, no. 5, 1 May 2009 (2009-05-01), pages A - 165, XP026111292, ISSN: 0016-5085, [retrieved on 20090501], DOI: 10.1016/S0016-5085(09)60745-9
"NCode(TM) Multi-species miRNA Microarray Probe Set Version 2.0", 1 May 2009 (2009-05-01), XP055013130, Retrieved from the Internet [retrieved on 20111125]
SUNG-CHOU LI ET AL: "Intronic MicroRNA: Discovery and Biological Implications", DNA AND CELL BIOLOGY, MARY ANN LIEBERT, NEW YORK, NY, US, vol. 26, no. 4, 1 April 2007 (2007-04-01), pages 195 - 207, XP008124956, ISSN: 1044-5498
"SEQ ID NO 486 of EP2112235 disclosing has-miR-766", 31 October 2009 (2009-10-31), XP055012964, Retrieved from the Internet
FRIIS-HANSEN L ET AL: "1072 Mir-449 Inhibits Growth of Gastric Cancer Cells Partly By Inhibiting the Expression of Met and Amphiregulin", GASTROENTEROLOGY, ELSEVIER, PHILADELPHIA, PA, vol. 136, no. 5, 1 May 2009 (2009-05-01), pages A - 165, XP026111292, ISSN: 0016-5085, [retrieved on 20090501], DOI: 10.1016/S0016-5085(09)60745-9
"NCode(TM) Multi-species miRNA Microarray Probe Set Version 2.0", 1 May 2009 (2009-05-01), XP055013130, Retrieved from the Internet
Attorney, Agent or Firm:
ISENBRUCK BÖSL HÖRSCHLER LLP et al. (Prinzregentenstrasse 68, München, DE)
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