METHODS AND DEVICES FOR STORING AND DISPENSING LIQUIDS

Title:

METHODS AND DEVICES FOR STORING AND DISPENSING LIQUIDS

Document Type and Number:

WIPO Patent Application WO2001077640

Kind Code:

A3

Abstract:

In a liquid handling system including a liquid handling substrate having a plurality of channels for conducting a liquid sample in said substrate, where the channels terminate in a plurality of exit ports in an outer surface of the substrate for transfer of a quantity of the liquid sample. The handling system also includes a liquid storage and dispensing substrate having a plurality of separable cartridges corresponding to the channels, with each cartridge terminating at a microelectro mechanical system (MEMS) comprising a laminate of glass, silicon and a piezoelectric substance. The handling system further includes a liquid detecting system comprising a light emitting diode and a photo-detector, where each channel includes a reservoir in communication with a corresponding cartridge creating an interface therebetween. The handling system enables a method for storing and dispensing liquids including drawing a liquid sample into the channels either by capillary action, vacuum, electroosmotic flow, a minipump or any combination thereof, storing the liquid sample into the cartridge, and dispensing the liquid sample.

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Inventors:

HUBBARD ALLYN E (US)
KALE SAMESH (US)
SQUINTO STEPHEN P (US)
ROLLINS SCOTT A (US)
SPRINGHORN JEREMY (US)
AKKAPEDDI PRASAD R (US)

Application Number:

PCT/US2001/011461

Publication Date:

March 28, 2002

Filing Date:

April 05, 2001

Export Citation:

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Assignee:

ALEXION PHARMA INC (US)
HUBBARD ALLYN E (US)
KALE SAMESH (US)
SQUINTO STEPHEN P (US)
ROLLINS SCOTT A (US)
SPRINGHORN JEREMY (US)
AKKAPEDDI PRASAD R (US)

International Classes:

B01J19/00; B81B3/00; G01N35/10; C40B60/14; C40B70/00; (IPC1-7): B01L3/02; B01J19/00; G01N35/10

Foreign References:

EP1101532A2	2001-05-23
EP1093855A2	2001-04-25
US6001309A	1999-12-14
US5658802A	1997-08-19
DE19737173A1	1999-03-18
EP0545284A1	1993-06-09
EP0434149A2	1991-06-26

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