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Title:
METHODS FOR ELIMINATING HEPATITIS B VIRUS CCCDNA AND RCDNA AND THE HEPATITIS B DRUGS USED IN THE METHODS THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/122555
Kind Code:
A3
Abstract:
Disclosed herein is a method of treating human chronic hepatitis B virus infection by reducing or eliminating cccDNA in liver cell of an HBV infected patient for 3 months or longer.

Inventors:
ZHANG YONG-YUAN (US)
Application Number:
PCT/US2022/081966
Publication Date:
November 02, 2023
Filing Date:
December 21, 2022
Export Citation:
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Assignee:
HBVTECH LLC (US)
International Classes:
A61P31/20; A61K39/42; C07K16/08; A61K39/29; C12N15/85
Domestic Patent References:
WO2019240503A12019-12-19
Foreign References:
US20210040183A12021-02-11
US20210052566A12021-02-25
US20170152303A12017-06-01
Other References:
LI ET AL.: "A potent human neutralizing antibody Fc-dependently reduces established HBV infections", ELIFE, vol. 6, no. e26738, 26 September 2017 (2017-09-26), pages 1 - 30, XP055727358, DOI: 10.7554/eLife.26738
Attorney, Agent or Firm:
CHEN, Xi (US)
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