Title:
METHODS AND FORMULATION FOR IMPROVING ORAL AVAILABILITY OF CPT-11 WHILE REDUCING CPT-11 INDUCED GASTRONINTESTINAL TOXICITY IN CANCER THERAPY
Document Type and Number:
WIPO Patent Application WO/2016/062245
Kind Code:
A1
Abstract:
Disclosed herein are methods and formulation for enhancing oral availability of CPT-11 during cancer therapy while at the same time, reducing its gastrointestinal (GI) toxicity, thus the methods and formulations as disclosed herein may augment the efficacy of cancer therapy.
Inventors:
LIAO PEI-RU (CN)
CHI KUAN-HUA (CN)
CHI KUAN-HUA (CN)
Application Number:
PCT/CN2015/092401
Publication Date:
April 28, 2016
Filing Date:
October 21, 2015
Export Citation:
Assignee:
JOHNPRO BIOTECH INC (CN)
International Classes:
A61K31/353; A61K9/20; A61K9/48; A61K31/357; A61K31/4745; A61K31/575; A61P1/00; A61P1/12; A61P7/04; A61P35/00
Domestic Patent References:
| WO2003055494A1 | 2003-07-10 | |||
| WO1999065493A1 | 1999-12-23 |
Attorney, Agent or Firm:
SHANGHAI PATENT & TRADEMARK LAW OFFICE, LLC (Shanghai 3, CN)
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