Title:
METHODS FOR IDENTIFYING NOVEL MULTIMERIC AGENTS THAT MODULATE RECEPTORS
Document Type and Number:
WIPO Patent Application WO1999066944
Kind Code:
A9
Abstract:
Disclosed are novel multi-binding compounds (agents) which bind cellular receptors. The compounds of this invention comprise a plurality of ligands each of which can bind to such cellular receptors thereby modulating the biological processes/functions thereof. Each of the ligands is covalently attached to a linker or linkers which may be the same or different to provide for the multi-binding compound. The linker is selected such that the multi-binding compound so constructed demonstrates increased modulation or disruption of the biological processes/functions of the cell. Also disclosed is a method for identifying such novel multi-binding compounds which bind cellular receptors and a method for generating a mixture of such novel multi-binding compounds.
More Like This:
| JPS6042782 | [Title of the Invention] Phenyl propylamine |
| WO/2022/241303 | COMPOSITION AND METHOD FOR TREATING COVID-19 |
Inventors:
MARQUESS DANIEL (US)
MAMMEN MATHAI (US)
GRIFFIN JOHN H (US)
MAMMEN MATHAI (US)
GRIFFIN JOHN H (US)
Application Number:
PCT/US1999/012989
Publication Date:
July 27, 2000
Filing Date:
June 08, 1999
Export Citation:
Assignee:
ADVANCED MEDICINE INC (US)
MARQUESS DANIEL (US)
MAMMEN MATHAI (US)
GRIFFIN JOHN H (US)
MARQUESS DANIEL (US)
MAMMEN MATHAI (US)
GRIFFIN JOHN H (US)
International Classes:
A61K31/13; A61K31/136; A61K31/137; A61K31/155; A61K31/16; A61K31/18; A61K31/27; A61K31/40; A61K31/4015; A61K31/403; A61K31/404; G01N33/50; A61K31/41; A61K31/4164; A61K31/4178; A61K31/4184; A61K31/435; A61K31/437; A61K31/44; A61K31/4402; A61K31/4427; A61K31/4439; A61K31/445; A61K31/454; A61K31/4545; A61K31/47; A61K31/4706; A61K31/4709; A61K31/485; A61K31/495; A61K31/496; A61K31/498; A61K31/506; A61K31/517; A61K31/519; A61K31/55; A61K31/551; A61K31/5517; A61K31/662; A61K38/00; A61K45/00; A61K47/48; A61P9/02; A61P9/04; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/02; A61P13/08; A61P15/06; A61P17/04; A61P21/00; A61P25/00; A61P25/02; A61P25/04; A61P25/06; A61P25/08; A61P25/14; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P27/16; A61P43/00; C07B61/00; C07C211/00; C07C213/00; C07C215/00; C07C215/34; C07C215/60; C07C217/00; C07C217/08; C07C217/10; C07C217/48; C07C217/58; C07C217/90; C07C237/08; C07C271/12; C07C311/37; C07C323/44; C07C323/62; C07D207/06; C07D207/08; C07D207/26; C07D209/08; C07D211/14; C07D211/18; C07D211/42; C07D211/52; C07D211/56; C07D211/60; C07D211/72; C07D211/84; C07D213/30; C07D213/38; C07D213/56; C07D213/74; C07D213/75; C07D213/80; C07D215/22; C07D215/48; C07D221/26; C07D221/28; C07D223/04; C07D235/18; C07D235/30; C07D239/95; C07D241/44; C07D249/12; C07D257/04; C07D263/32; C07D263/34; C07D265/32; C07D277/24; C07D277/28; C07D277/34; C07D295/02; C07D295/06; C07D295/08; C07D295/18; C07D295/20; C07D401/04; C07D401/12; C07D401/14; C07D403/02; C07D403/14; C07D413/06; C07D413/14; C07D417/12; C07D471/04; C07D471/08; C07D487/04; C07D495/04; C07D519/00; C07K1/04; C07K2/00; C07K4/00; C07K7/14; C07K16/28; C40B20/00; G01N33/15; G01N33/53; G01N33/543; G01N33/566; G01N33/94; G01N37/00; (IPC1-7): A61K38/00; A61K39/00; A61K39/44; A61K39/395; A61K51/00; A01N43/00; C07K2/00; C07K4/00; G01N33/53; G01N33/543; G01N33/566
Download PDF: