Title:
METHODS OF IDENTIFYING, PREVENTING, AND TREATING VIRULENT HAND FOOT AND MOUTH DISEASE VIRUS USING REPLIKIN SEQUENCES
Document Type and Number:
WIPO Patent Application WO/2014/127155
Kind Code:
A3
Abstract:
The present invention provides methods of predicting the virulence of Hand Foot and Mouth Disease viruses and outbreaks of said viruses comprising comparing Replikin concentrations in different isolates of virus and identifying relatively-virulent isolates as those having relatively-higher Replikin concentrations. The present invention further provides diagnostic, preventive, and therapeutic applications for Replikin peptides identified in Hand Foot and Mouth Disease viruses including Replikin peptides identified as shared among viruses that cause Hand Foot and Mouth Disease.
Inventors:
BOGOCH SAMUEL (US)
BOGOCH ELENORE S (US)
BOGOCH SAMUEL WINSTON (US)
BORSANYI ANNE-ELENORE BOGOCH (US)
BOGOCH ELENORE S (US)
BOGOCH SAMUEL WINSTON (US)
BORSANYI ANNE-ELENORE BOGOCH (US)
Application Number:
PCT/US2014/016303
Publication Date:
December 04, 2014
Filing Date:
February 13, 2014
Export Citation:
Assignee:
BOGOCH SAMUEL (US)
BOGOCH ELENORE S (US)
BOGOCH SAMUEL WINSTON (US)
BORSANYI ANNE-ELENORE BOGOCH (US)
BOGOCH ELENORE S (US)
BOGOCH SAMUEL WINSTON (US)
BORSANYI ANNE-ELENORE BOGOCH (US)
International Classes:
A61K38/00; C07K2/00; C07K4/00; C07K5/00; C07K7/00; C07K14/00; C07K16/00; C07K17/00
Domestic Patent References:
| WO2012108840A1 | 2012-08-16 |
Foreign References:
| US20020151677A1 | 2002-10-17 | |||
| US20050123550A1 | 2005-06-09 |
Other References:
CHANG, LY ET AL.: "Viral Virulence Factors: EV71 Genetics Of 3C And Its Correlation With Clinical Outcome: 3C Protein", PARTIAL [ENTEROVIRUS A71
Attorney, Agent or Firm:
NICHOLSON, Daren, P. (Lebanon, TN, US)
Download PDF: