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Title:
METHODS FOR THE MANUFACTURE OF CANNABINOID PRODRUGS, PHARMACEUTICAL FORMULATIONS AND THEIR USE
Document Type and Number:
WIPO Patent Application WO/2017/216362
Kind Code:
A1
Abstract:
Described are methods for producing cannabinoid prodrugs using enzyme-catalysed synthesis / chemical modifications as well as methods for formulating such prodrugs in a pharmaceutically acceptable form and their use as therapeutic agents for treating diseases.

Inventors:
PEET RICHARD C (IE)
KAVARANA MALCOLM J (IE)
Application Number:
PCT/EP2017/064806
Publication Date:
December 21, 2017
Filing Date:
June 16, 2017
Export Citation:
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Assignee:
FULL SPECTRUM LABORATORIES LTD (IE)
International Classes:
C07D311/80; A61K31/352; A61P25/04; A61P29/00; C12P13/08; C12P15/00
Domestic Patent References:
WO2008134668A22008-11-06
WO2009018389A12009-02-05
WO2015196275A12015-12-30
WO2016030828A12016-03-03
Foreign References:
US20150045282A12015-02-12
US20160053220A12016-02-25
Other References:
ZEHAVI U ET AL: "O- and C-D-glucosyluronic acid derivatives of tetrahydrocannabinol: Synthesis and differential behavior to beta-glucuronidase", CARBOHYDRATE RESEARCH, PERGAMON, GB, vol. 98, no. 1, 1 December 1981 (1981-12-01), pages 143 - 147, XP026619169, ISSN: 0008-6215, [retrieved on 19811201], DOI: 10.1016/S0008-6215(00)87152-9
FOCELLA, A ET AL., J. ORG. CHEM., vol. 42, no. 21, 1977, pages 3456 - 3457
TAURA ET AL., THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 21, 1996, pages 17411 - 17416
BALASUBRAHMANYAM ET AL.: "Organic Synthesis, Collective", vol. V, 1973, JOHN WILEY & SONS, INC., pages: 439 - 444
Attorney, Agent or Firm:
SCHWEGMAN LUNDBERG WOESSNER LIMITED (GB)
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