METHODS FOR MANUFACTURING TETRANOR-PROSTAGLANDIN D, J, E, A AND F METABOLITES

Title:

METHODS FOR MANUFACTURING TETRANOR-PROSTAGLANDIN D, J, E, A AND F METABOLITES

Document Type and Number:

WIPO Patent Application WO/2011/159740

Kind Code:

A3

Abstract:

The present invention generally relates to synthetic methods for preparing tetranor-prostaglandin D, J, E, A, and F metabolites.

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Inventors:

ENDRES GREGORY W (US)
KORNILOV ANDRIY M (US)
UZIEBLO ADAM (US)

Application Number:

PCT/US2011/040408

Publication Date:

April 12, 2012

Filing Date:

June 14, 2011

Export Citation:

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Assignee:

CAYMAN CHEMICAL CO INC (US)
ENDRES GREGORY W (US)
KORNILOV ANDRIY M (US)
UZIEBLO ADAM (US)

International Classes:

C07C405/00; C07C51/347; C07C59/82

Foreign References:

US3992413A	1976-11-16
US3944593A	1976-03-16
US20050209337A1	2005-09-22

Other References:

NEALE J.R. ET AL.: "Liquid chromatography-tandem mass spectrometric quantification of the dehydration product of tetranor PGE-M, the major urinary metabolite of prostaglandin E(2) in human urine.", JOURNAL OF CHROMATOGRAPHY B, vol. 871, no. 1, 2008, pages 72 - 77, XP023438101

Attorney, Agent or Firm:

HAYS, Steven, W. (LLPOne Oxford Centre, 38th Floor,301 Grant Stree, Pittsburgh Pennsylvania, US)

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