Title:
METHODS AND MATERIALS FOR HIGH GRADIENT MAGNETIC SEPARATION OF BIOLOGICAL MATERIALS
Document Type and Number:
WIPO Patent Application WO1990007380
Kind Code:
A3
Abstract:
Improvements in the existing procedures and materials for conduct of high gradient magnetic separation (HGMS) are disclosed. Superior superparamagnetic particles, optionally coated with a polysaccharide or other, usually organic, materials can be prepared in uniform compositions with homogeneous magnetizations. The coating can conveniently be conjugated to a specific binding moiety complementary to a biological material whose purification or separation is desired. In addition, plastic coated matrices which form superior magnetic gradient-intensifying supports are disclosed, along with improved methods and apparatus to conduct HGMS.
More Like This:
Inventors:
MILTENYI STEFAN (DE)
Application Number:
PCT/EP1989/001602
Publication Date:
September 07, 1990
Filing Date:
December 22, 1989
Export Citation:
Assignee:
MILTENYI STEFAN (DE)
International Classes:
B03C1/00; B03C1/01; B03C1/033; B03C1/034; G01N33/543; (IPC1-7): B03C1/00; B03C1/025; G01N33/551
Domestic Patent References:
| WO1983002405A1 | 1983-07-21 |
Foreign References:
| EP0125995A2 | 1984-11-21 | |||
| US4452773A | 1984-06-05 | |||
| US4677067A | 1987-06-30 | |||
| DE3624626A1 | 1988-01-28 | |||
| US4526681A | 1985-07-02 |
Other References:
IBM Technical Disclosure Bulletin, Vol. 19, No. 7, December 1976, (New York, US), M. RONAY: "Addition of Surfactants to Water-Magnetite Suspensions", pages 2760-2763
IEEE Transactions on Magnetics, Vol. MAG-22, No. 5, September 1986, IEEE, (New York, US), K. O' GRADY et al.: "Magnetic Filtration of Ferrofluids", pages 1134-1136
IEEE Transactions on Magnetics, Volume MAG-18, No. 6, November 1982, IEEE, (New York, US), J.Y. HWANG et al.: "Selective Seeding for Magnetic Separation", pages 1689-1691
IEEE Transactions on Magnetics, Volume MAG-20, No. 1, January 1984, IEEE, (New York, US), M. TAKAYASU et al.: "Magnetic Separation Utilizing a Magnetic Susceptibility Gradient", pages 155-159
IEEE Transactions on Magnetics, Vol. MAG-22, No. 5, September 1986, IEEE, (New York, US), K. O' GRADY et al.: "Magnetic Filtration of Ferrofluids", pages 1134-1136
IEEE Transactions on Magnetics, Volume MAG-18, No. 6, November 1982, IEEE, (New York, US), J.Y. HWANG et al.: "Selective Seeding for Magnetic Separation", pages 1689-1691
IEEE Transactions on Magnetics, Volume MAG-20, No. 1, January 1984, IEEE, (New York, US), M. TAKAYASU et al.: "Magnetic Separation Utilizing a Magnetic Susceptibility Gradient", pages 155-159
Download PDF:
Previous Patent: PROCESS AND DEVICE FOR CRUSHING BULK MATERIALS
Next Patent: FILTER FOR SEPARATING PARTICLES FROM GASES
Next Patent: FILTER FOR SEPARATING PARTICLES FROM GASES