Title:
METHODS AND MATERIALS RELATING TO PREADIPOCYTE FACTOR-1-LIKE (PREF-1-LIKE) POLYPEPTIDES AND POLYNUCLEOTIDES
Document Type and Number:
WIPO Patent Application WO2001057233
Kind Code:
A3
Abstract:
The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted Pref-1-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from adult human brain (Hyseq clone identification numbers 7958079 (SEQ ID NO:1)). Other aspects of the invention include vectors containing processes for producing novel human secreted Pref-1-like polypeptides, and antibodies specific for such polypeptides.
Inventors:
KUO CHIAUYUN (US)
HALEY DANA A (US)
BOYLE BRYAN J (US)
ARTERBURN MATTHEW C (US)
TANG Y TOM (US)
LIU CHENGHUA (US)
DRMANAC RADOJE A (US)
HALEY DANA A (US)
BOYLE BRYAN J (US)
ARTERBURN MATTHEW C (US)
TANG Y TOM (US)
LIU CHENGHUA (US)
DRMANAC RADOJE A (US)
Application Number:
PCT/US2001/002611
Publication Date:
March 07, 2002
Filing Date:
January 25, 2001
Export Citation:
Assignee:
HYSEQ INC (US)
KUO CHIAUYUN (US)
HALEY DANA A (US)
BOYLE BRYAN J (US)
ARTERBURN MATTHEW C (US)
TANG Y TOM (US)
LIU CHENGHUA (US)
DRMANAC RADOJE A (US)
KUO CHIAUYUN (US)
HALEY DANA A (US)
BOYLE BRYAN J (US)
ARTERBURN MATTHEW C (US)
TANG Y TOM (US)
LIU CHENGHUA (US)
DRMANAC RADOJE A (US)
International Classes:
C12N15/09; A61K38/00; A61P3/04; A61P3/06; A61P3/10; A61P21/00; A61P35/00; A61P37/00; C07K14/47; C07K14/475; C07K14/705; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12Q1/02; C12Q1/68; (IPC1-7): C12Q1/68; C07H21/02; C07K14/00
Other References:
DATABASE GENEMBL [online] CARLSSON ET AL.: "Growth hormone and prolactin stimulate the expression of rat poreadipocyte factor-1/delta-like protein in pancreatic islet: molecular cloning and expressin pattern during development and growth of the endocrine pancrease", XP002945245, Database accession no. U25680
WATSON ET AL.: "Recombinant DNA: A short course", 1983, W.H. FREEMAN AND COMPANY, NEW YORK, XP002945246
See also references of EP 1261736A4
WATSON ET AL.: "Recombinant DNA: A short course", 1983, W.H. FREEMAN AND COMPANY, NEW YORK, XP002945246
See also references of EP 1261736A4
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