Title:
METHODS AND MEANS FOR MOLECULAR CLASSIFICATION OF COLORECTAL CANCERS
Document Type and Number:
WIPO Patent Application WO/2012/087144
Kind Code:
A3
Abstract:
The invention relates to methods of typing a sample from a colorectal cancer patient based on the levels of RNA expression products in a cancer cell of the patient. The invention further relates to methods for determining a strategy for treatment of a patient suffering from colorectal cancer, and to methods for assigning treatment to a patient suffering from colorectal cancer.
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Inventors:
ROEPMAN PAUL (NL)
SIMON IRIS (NL)
SUN TIAN (NL)
SIMON IRIS (NL)
SUN TIAN (NL)
Application Number:
PCT/NL2011/050901
Publication Date:
September 20, 2012
Filing Date:
December 23, 2011
Export Citation:
Assignee:
AGENDIA N V (NL)
ROEPMAN PAUL (NL)
SIMON IRIS (NL)
SUN TIAN (NL)
ROEPMAN PAUL (NL)
SIMON IRIS (NL)
SUN TIAN (NL)
International Classes:
C12Q1/68
Domestic Patent References:
| WO2010101916A1 | 2010-09-10 |
Foreign References:
| EP2177615A1 | 2010-04-21 | |||
| EP2202320A1 | 2010-06-30 |
Other References:
PATTERSON KATE I ET AL: "Dual-specificity phosphatases: critical regulators with diverse cellular targets", BIOCHEMICAL JOURNAL, vol. 418, no. Part 3, March 2009 (2009-03-01), pages 475 - 489, XP002673568
WU QIHAN ET AL: "Molecular cloning and characterization of a novel Dual-specificity Phosphatase18 gene from human fetal brain.", BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1625, no. 3, 20 February 2003 (2003-02-20), pages 296 - 304, XP004410862, ISSN: 0006-3002
OSELLAME L D ET AL: "S9.9 MiD51 and MiD49: New mediators of mammalian mitochondrial distribution", BIOCHIMICA ET BIOPHYSICA ACTA. BIOENERGETICS, AMSTERDAM, NL, vol. 1777, 19 July 2008 (2008-07-19), pages S57, XP022758938, ISSN: 0005-2728, [retrieved on 20080619], DOI: 10.1016/J.BBABIO.2008.05.224
JANSOVA E ET AL: "Comparative transcriptome maps: a new approach to the diagnosis of colorectal carcinoma patients using cDNA microarrays", CLINICAL GENETICS, vol. 69, no. 3, March 2006 (2006-03-01), pages 218 - 227, XP002633596, ISSN: 0009-9163
WU QIHAN ET AL: "Molecular cloning and characterization of a novel Dual-specificity Phosphatase18 gene from human fetal brain.", BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1625, no. 3, 20 February 2003 (2003-02-20), pages 296 - 304, XP004410862, ISSN: 0006-3002
OSELLAME L D ET AL: "S9.9 MiD51 and MiD49: New mediators of mammalian mitochondrial distribution", BIOCHIMICA ET BIOPHYSICA ACTA. BIOENERGETICS, AMSTERDAM, NL, vol. 1777, 19 July 2008 (2008-07-19), pages S57, XP022758938, ISSN: 0005-2728, [retrieved on 20080619], DOI: 10.1016/J.BBABIO.2008.05.224
JANSOVA E ET AL: "Comparative transcriptome maps: a new approach to the diagnosis of colorectal carcinoma patients using cDNA microarrays", CLINICAL GENETICS, vol. 69, no. 3, March 2006 (2006-03-01), pages 218 - 227, XP002633596, ISSN: 0009-9163
Attorney, Agent or Firm:
JANSEN, C.M. (JR Den Haag, NL)
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