Title:
METHODS OF OPHTHALMIC ADMINISTRATION
Document Type and Number:
WIPO Patent Application WO2000007565
Kind Code:
A3
Abstract:
Intrascleral injection of a therapeutic or diagnostic material at a location overlying the retina provides a minimally invasive technique for delivering the agent to the posterior segment of the eye. The procedure also allows for close proximity of the material to the targeted site and can be effectively used to treat conditions associated with the posterior segment of the eye, including macular degeneration, vein occlusion, and diabetic retinopathy. The sclera can be used to hold a depot of the material such as for sustained released or as a conduit for propelling material through whereby the material is delivered immediately to the underlying tissues but without physically penetrating the sclera with an instrument or otherwise unreasonably traumatizing the eye.
Inventors:
BOWMAN LYLE M
PFEIFFER JAMES F
CLARK LESLIE A
HECKER KARL I
PFEIFFER JAMES F
CLARK LESLIE A
HECKER KARL I
Application Number:
PCT/US1999/017543
Publication Date:
May 11, 2000
Filing Date:
August 02, 1999
Export Citation:
Assignee:
INSITE VISION INC (US)
International Classes:
A61F9/007; A61K9/00; A61K9/107; A61K31/00; A61K38/19; A61M31/00; A61K48/00; A61K49/00; A61P9/10; A61P21/02; A61P27/02; A61P27/06; A61P27/12; A61K38/12; (IPC1-7): A61K9/00; A61K38/55; A61K38/46; A61K48/00; A61K39/395; A61P21/02
Domestic Patent References:
| WO1996009838A1 | 1996-04-04 | |||
| WO1992008406A1 | 1992-05-29 | |||
| WO1997041844A1 | 1997-11-13 |
Other References:
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; VERBEEK A M ET AL: "Recurrent intrascleral cyst after strabismus surgery.", XP002130928, retrieved from STN Database accession no. 97024955
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