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Title:
METHODS FOR PREPARING Β-ALANINE, Β-ALANINE SALT AND PANTOTHENATE
Document Type and Number:
WIPO Patent Application WO/2020/187256
Kind Code:
A1
Abstract:
Provided is a method for preparing β-alanine, the method comprising: preparing a β-alanine product from a reactant containing fumaric acid and aqueous ammonia in the presence of a catalyst, wherein the catalyst contains a catalyst composition containing aspartase and L-aspartic acid-α-decarboxylase, and adding fumaric acid during the reaction, wherein the total moles of the fumaric acid added is equal to the initial moles of the aqueous ammonia in the reactant minus the initial moles of the fumaric acid in the reactant. Also provided are methods for preparing a β-alanine salt (in particular calcium β-alanine, sodium β-alanine, and potassium β-alanine) and a pantothenate (in particular calcium pantothenate, sodium pantothenate, and potassium pantothenate).

Inventors:
LAU MAN KIT (CN)
CHEN YAN (CN)
CHIEW ANSEN (CN)
LU CHENGLIANG (CN)
ZENG CONGMING (CN)
SU JINHUAN (CN)
LU WEIHUA (CN)
Application Number:
PCT/CN2020/079957
Publication Date:
September 24, 2020
Filing Date:
March 18, 2020
Export Citation:
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Assignee:
GUANG AN MOJIA BIOTECHNOLOGY CO LTD (CN)
International Classes:
C12P13/06; C07C227/18; C07C231/02; C07C231/24
Foreign References:
CN102851333A2013-01-02
CN103320480A2013-09-25
CN108191688A2018-06-22
CN1285730A2001-02-28
JPH1042886A1998-02-17
Other References:
ALTSCHUL S.F. ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 - 410
STEPHEN F. ET AL., NUCLEIC ACIDS RES., vol. 25, 1997, pages 3389 - 3402
HIGGINS D.G. ET AL., METHODS IN ENZYMOLOGY, vol. 266, 1996, pages 383 - 402
LARKIN M.A. ET AL., BIOINFORMATICS, vol. 23, no. 21, 2007, pages 2947 - 8
LI Y., APPL. MICROBIOL. BIOTECHNOL, vol. 101, 2017, pages 6015 - 6021
Attorney, Agent or Firm:
JUN HE LAW OFFICES (CN)
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