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Patent Searching and Data


Title:
METHODS OF PRODUCING 7-CARBON CHEMICALS VIA PYRUVATE AND SUCCINATE SEMIALDEHYDE ALDOL CONDENSATION
Document Type and Number:
WIPO Patent Application WO/2014/105797
Kind Code:
A8
Abstract:
This document describes biochemical pathways for producing one or more of pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine and 1,7-heptanediol by forming one or two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups, in a C7 aliphatic backbone substrate produced from succinate semialdehyde or pyruvate. These pathways, metabolic engineering and cultivation strategies described herein rely on the aldol condensation of succinate semialdehyde and pyruvate.

Inventors:
BOTES ADRIANA LEONORA (GB)
CONRADIE ALEX VAN ECK (GB)
CHEN CHANGLIN (GB)
PEARLMAN PAUL S (US)
Application Number:
PCT/US2013/077430
Publication Date:
February 19, 2015
Filing Date:
December 23, 2013
Export Citation:
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Assignee:
INVISTA NORTH AMERICA SARL (US)
International Classes:
C12P7/18; C12P7/42; C12P7/44; C12P13/00; C12P13/02
Attorney, Agent or Firm:
MCCORMICK GRAHAM, Monica et al. (P.O. Box 1022Minneapolis, Minnesota, US)
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