Title:
METHODS OF RESISTANT BACTERIAL DISEASE TREATMENT USING METAL-COMPLEXED TETRACYCLINE ANTIBIOTICS
Document Type and Number:
WIPO Patent Application WO2003066064
Kind Code:
A3
Abstract:
A method for treating bacterial diseases, including bacterial infections, that are otherwise resistant to antibiotics, such as tetracycline or a quinolone and related compounds, using metal-complexed antibiotics is disclosed. Also disclosed is a method for protecting against such diseases. The metal-complexed antibiotics include tetracyclines or quinolones complexed with metals such as iron, copper and calcium.
More Like This:
| JP2023553687 | Benzene ring compounds and their uses |
| WO/2002/070486 | NITROGEN-CONTAINING HETEROARYL COMPOUNDS HAVING HIV INTEGRASE INHIBITORY ACTIVITY |
| WO/2015/008007 | NOVEL SOLANIDINE-DERIVED COMPOUNDS |
Inventors:
ISBISTER JENEFIR (US)
Application Number:
PCT/US2003/003588
Publication Date:
April 15, 2004
Filing Date:
February 06, 2003
Export Citation:
Assignee:
ADVANCIS PHARMACEUTICALS CORP (US)
ISBISTER JENEFIR (US)
ISBISTER JENEFIR (US)
International Classes:
A61K31/4375; A61K31/4709; A61K31/496; A61K31/5383; A61K31/65; A61K33/06; A61K33/24; A61K33/26; A61K33/30; A61K33/32; A61K33/34; A61K45/06; A61K47/48; A61P17/00; A61P31/04; (IPC1-7): A61K31/65; A61K33/06; A61K31/496; A61K45/06; A61K31/4375; A61K47/48; A61K31/5383; A61P31/04; A61K31/4709; A61P17/00; A61K33/26
Domestic Patent References:
| WO1999029322A1 | 1999-06-17 |
Foreign References:
| US5494903A | 1996-02-27 | |||
| GB845649A | 1960-08-24 | |||
| GB742157A | 1955-12-21 | |||
| CH447190A | 1967-11-30 |
Other References:
LUNESTAD B T ET AL: "REDUCTION IN THE ANTIBACTERIAL EFFECT OF OXYTETRACYCLINE IN SEA WATER BY COMPLEX FORMATION WITH MAGNESIUM AND CALCIUM", DISEASES OF AQUATIC ORGANISMS, vol. 9, no. 1, 1990, pages 67 - 72, XP008020430, ISSN: 0177-5103
NEUVONEN P J: "Interactions with the absorption of tetracyclines.", DRUGS. SWITZERLAND 1976, vol. 11, no. 1, 1976, pages 45 - 54, XP008020432, ISSN: 0012-6667
CHOHAN ZAHID H ET AL: "Antibacterial Co(II), Cu(II), Ni(II) and Zn(II) complexes of thiadiazoles schiff bases.", METAL-BASED DRUGS, vol. 8, no. 2, 2001, pages 95 - 101, XP008020433, ISSN: 0793-0291
KALLESTAD LABORATORIES: "Polymyxin-metal complexes and their biological use", EXPERT OPIN. THER. PATENTS, vol. 12, no. 1, January 2002 (2002-01-01), pages 139 - 140, XP002251270
NEUVONEN P J: "Interactions with the absorption of tetracyclines.", DRUGS. SWITZERLAND 1976, vol. 11, no. 1, 1976, pages 45 - 54, XP008020432, ISSN: 0012-6667
CHOHAN ZAHID H ET AL: "Antibacterial Co(II), Cu(II), Ni(II) and Zn(II) complexes of thiadiazoles schiff bases.", METAL-BASED DRUGS, vol. 8, no. 2, 2001, pages 95 - 101, XP008020433, ISSN: 0793-0291
KALLESTAD LABORATORIES: "Polymyxin-metal complexes and their biological use", EXPERT OPIN. THER. PATENTS, vol. 12, no. 1, January 2002 (2002-01-01), pages 139 - 140, XP002251270
Download PDF: