METHODS AND SYSTEMS FOR THE RAPID DETECTION OF LISTERIA USING INFECTIOUS AGENTS RELATED APPLICATIONS [0001] This application claims priority to U.S. provisional patent application No.63/145,772 filed on February 4, 2021. The disclosure of U.S. provisional patent application No.63/145,772, is incorporated by reference in its entirety herein. The disclosures of U.S. Application Nos. 13/773,339, 14/625,481, 15/263,619, 15/409,258, and 16/905/607 are hereby incorporated by reference in their entirety herein. FIELD OF THE INVENTION [0002] This invention relates to compositions, methods, systems, and kits for the detection of microorganisms using infectious agents. BACKGROUND [0003] There is a strong interest in improving speed and sensitivity for detection of bacteria, viruses, and other microorganisms in biological, food, water, and clinical samples. Microbial pathogens can cause substantial morbidity among humans and domestic animals, as well as immense economic loss. Also, detection of microorganisms is a high priority for the Food and Drug Administration (FDA) and Centers for Disease Control (CDC), as well as the United States Department of Agriculture (USDA), given outbreaks of life-threatening or fatal illness caused by ingestion of food contaminated with certain microorganisms, e.g., Listeria spp., Salmonella spp., or Staphylococcus spp. [0004] In particular, Listeria spp. are known to cause the potentially serious infection, listeriosis. Listeria spp., such as L. monocytogenes, are typically transmitted through ingestion of contaminated food products. L. monocytogenes is a gram-positive bacterium commonly associated with contamination of food products, including but not limited to, milk, seafood, poultry, and meat. Food-borne illnesses, such as listeriosis, can be prevented by detecting contaminated foods prior to consumer availability. [0005] Traditional microbiological tests for the detection of bacteria rely on non-selective and selective enrichment cultures followed by plating on selective media and further testing to confirm suspect colonies. Such procedures can require as long as seven days. For examples, traditional tests for the detection of Listeria spp. in food products are complex and time consuming requiring 24-48 hour enrichment periods followed by additional lengthy testing with a total time for detection ranging from 5-7 days. A variety of rapid methods have been investigated and introduced into practice to reduce the time requirement. However, these methods have drawbacks. For example, polymerase chain reaction (PCR) tests, which also include an amplification step and therefore are capable of both very high sensitivity and selectivity; are economically limited to a small sample size. With dilute bacterial suspensions, most small subsamples will be free of cells and therefore purification and/or lengthy enrichment steps are still required.

[0006] The time required for traditional biological enrichment is dictated by the growth rate of the target bacterial population of the sample, by the effect of the sample matrix, and by the required sensitivity. Due to the time required for cultivation, these methods can take up to eight days, depending upon the organism to be identified and the source of the sample. This lag time is generally unsuitable as the contaminated food, water, or other product may have already made its way into livestock or humans. In addition, increases in antibiotic-resistant bacteria and biodefense considerations make rapid identification of bacterial pathogens in water, food and clinical samples critical priorities worldwide.

[0007] Therefore, there is a need for more rapid, simple, and sensitive detection and identification of microorganisms, such as bacteria and other potentially pathogenic microorganisms.

SUMMARY

[0008] Embodiments of the invention comprise compositions, methods, systems, and kits for the detection of microorganisms such as Listeria spp. The invention may be embodied in a variety of ways.

[0009] In some aspects, the invention comprises a recombinant bacteriophage comprising an indicator gene inserted into a late gene region of a bacteriophage genome. In some embodiments the recombinant bacteriophage is a genetically modified Listeria-specific bacteriophage genome. In certain embodiments the recombinant bacteriophage comprises a genetically modified bacteriophage genome derived from a bacteriophage that specifically recognizes Listeria spp. In some embodiments, the bacteriophage used to prepare the recombinant bacteriophage specifically infects one or more Listeria spp. In an embodiment, the recombinant bacteriophage can distinguish Listeria spp. in the presence of other types of bacteria. In some embodiments the recombinant bacteriophage specifically recognizes Listeria monocytogenes. In some embodiments the recombinant bacteriophage specifically recognizes Listeria grayi.

[0010] In some embodiments of recombinant indicator bacteriophage, the indicator gene can be codon-optimized and can encode a soluble protein product that generates an intrinsic signal or a soluble enzyme that generates signal upon reaction with substrate. Some recombinant bacteriophage further comprise an untranslated region upstream of a codon-optimized indicator gene, wherein the untranslated region includes a bacteriophage late gene promoter and a ribosomal entry site. In some embodiments, the indicator gene is a luciferase gene. The luciferase gene can be a naturally occurring gene, such as Oplophorus luciferase, Firefly luciferase, Lucia luciferase, or Renilla luciferase, or it can be a genetically engineered gene such as NANOLUC®.

[0011] Also disclosed herein are methods for preparing a recombinant indicator bacteriophage. Some embodiments include selecting a wild-type bacteriophage that specifically infects a target pathogenic bacterium; preparing a homologous recombination plasmid/vector comprising an indicator gene; transforming the homologous recombination plasmid/vector into target pathogenic bacteria; infecting the transformed target pathogenic bacteria with the selected wild-type bacteriophage, thereby allowing homologous recombination to occur between the plasmid/vector and the bacteriophage genome; and isolating a particular clone of recombinant bacteriophage. In some embodiments the selected wild-type bacteriophage is a /.z.s/cz'zzz-specific bacteriophage.

[0012] In some embodiments, preparing a homologous recombination plasmid/vector includes determining the natural nucleotide sequence in the late region of the genome of the selected bacteriophage; annotating the genome and identifying the major capsid protein gene of the selected bacteriophage; designing a sequence for homologous recombination downstream of the major capsid protein gene, wherein the sequence comprises a codon-optimized indicator gene; and incorporating the sequence designed for homologous recombination into a plasmid/vector. The step of designing a sequence can include inserting a genetic construct comprising an untranslated region, including a phage late gene promoter and ribosomal entry site, upstream of the codon-optimized indicator gene. In some embodiments, the phage late gene promoter is an exogenous promoter, different from any endogenous promoter in the phage genome. Thus, in some methods, the homologous recombination plasmid comprises an untranslated region including a bacteriophage late gene promoter and a ribosomal entry site upstream of the codon-optimized indicator gene.

[0013] Some embodiments of the invention are compositions that include a recombinant indicator bacteriophage as described herein. For example, compositions can include one or more wild-type or genetically modified infectious agents (e.g., bacteriophages) and one or more indicator genes. In some embodiments, the compositions, methods, systems and kits of the invention may comprise a cocktail of at least one recombinant bacteriophage for use in detection of microorganisms such as Listeria spp. In certain instances, the cocktail compositions is able to detect L. grayi.

[0014] In some embodiments, the invention comprises a method for detecting a microorganism of interest in a sample comprising the steps of incubating the sample with a recombinant bacteriophage that infects the microorganism of interest, wherein the recombinant bacteriophage comprises an indicator gene inserted into a late gene region of the bacteriophage such that expression of the indicator gene during bacteriophage replication following infection of host bacteria results in a soluble indicator protein product, and detecting the indicator protein product, wherein positive detection of the indicator protein product indicates that the microorganism of interest is present in the sample.

[0015] In some embodiments of methods for preparing recombinant indicator bacteriophage, the wild-type bacteriophage is a Listeria 5/?/?. -specific bacteriophage and the target pathogenic bacterium is Listeria spp. In some embodiments, isolating a particular clone of recombinant bacteriophage comprises a limiting dilution assay for isolating a clone that demonstrates expression of the indicator gene. [0016] Other aspects of the invention include methods for detecting bacteria, such as Listeria spp. in a sample, including steps of incubating the sample with a recombinant bacteriophage derived from A/.s/c/va-specific bacteriophage and detecting an indicator protein product produced by the recombinant bacteriophage, wherein positive detection of the indicator protein product indicates that Listeria spp. is present in the sample.

[0017] Listeria spp. are gram positive rod shaped bacteria that are ubiquitous in soil, water, and in several animals intended for consumption. Listeria spp. can grow at wide temperature and pH ranges and can tolerate high concentrations of sodium chloride allowing for a greater ability to contaminate food during processing. In humans, Listeria monocytogenes is of particular concern as the causative agent of Listeriosis. Listeriosis is usually caused by eating food that has been contaminated with L. monocytogenes. It is estimated that 1,600 people get Listeriosis each year, resulting in about 260 deaths. The infection is most likely to sicken pregnant women and their newborns, adults aged 65 or older, and people with weakened immune systems. Most concerning are infections occurring in pregnant women were the infection can lead to miscarriage, still birth, premature delivery, or even life-threating infections such as sepsis or meningitis in the newborn

[0018] In some embodiments, the invention includes methods for the detection of Listeria spp. using a recombinant bacteriophage derived from a bacteriophage that targets Listeria spp. The sample can be a food or water sample. In some embodiments, samples include environmental samples (e.g., sponges and swabs of surfaces or equipment for bacterial monitoring in factories and other processing facilities).

[0019] In some embodiments of methods for detecting bacteria, the sample is first incubated in conditions favoring growth for an enrichment period of 24 hours or less, 23 hours or less, 22 hours or less, 21 hours or less, 20 hours or less, 19 hours or less, 18 hours or less, 17 hours or less, 16 hours or less, 15 hours or less, 14 hours or less, 13 hours or less, 12 hours or less, 11 hours or less, 10 hours or less, or 9 hours or less, 8 hours or less, 7 hours or less, 6 hours or less, 5 hours or less, 4 hours or less, 3 hours or less, or 2 hours or less. In some embodiments, the sample is not enriched prior to detection. In some embodiments, the total time to results is less than 26 hours, 25 hours, 24 hours, 23 hours, 22 hours, 21 hours, 20 hours, 19 hours, 18 hours, 17 hours, 16 hours, 15 hours, 14 hours, 13 hours, 12 hours, 11 hours, 10 hours, 9 hours, 8 hours, 7 hours, 6 hours, 5 hours, 4 hours, 3 hours or 2 hours. In some embodiments, the ratio of signal to background generated by detecting the indicator is at least 2.0 or at least 2.5 or at least 3.0. In some embodiments, the method detects as few as 1, 10, 15, 20, 30, 40, 50, 60, 70, 80, 90, or 100 of the specific bacteria in a sample of a standard size for the food safety industry.

[0020] Additional embodiments include systems and kits for detecting Listeria spp., wherein the systems or kits include a recombinant bacteriophage derived from Listeria-specifc bacteriophage. Some embodiments further include a substrate for reacting with an indicator to detect the soluble protein product expressed by the recombinant bacteriophage. These systems or kits can include features described for the bacteriophage, compositions, and methods of the invention. In still other embodiments, the invention comprises non-transient computer readable media for use with methods or systems according to the invention.

BRIEF DESCRIPTION OF THE FIGURES

[0021] The present invention may be better understood by referring to the following nonlimiting figures.

[0022] Figure 1 depicts an indicator phage construct according to an embodiment of the invention illustrating insertion of a genetic construct comprising a luciferase gene, a bacteriophage late gene promoter, and a ribosomal binding site (RBS) inserted into the late (class III) region of a bacteriophage. The promoter depicted is in addition to and separate from the endogenous late gene promoter upstream of the endogenous late genes, such as the gene for major capsid protein (MCP).

[0023] Figure 2 shows the genome of bacteriophage LMA4, a myovirus (related to Listeria phage LMTA-94) which was obtained from sewage. A hypothetical gene homologous to the putative prohead protease p85protein is upstream of cps, the major capsid gene within the late gene region, consisting of structural genes, which code for virion proteins. Following the cps, is a transcriptional terminator, followed by a homolog to the LMTA-94 tail sheath protein (tsh). As these virion proteins are expressed at a very high level, any genes inserted into this region can be expected to have similar expression levels, as long as late gene promoters and/or other similar control elements are used. [0024] Figure 3 shows two homologous recombination plasmid construct designs carrying the luciferase gene used to construct the recombinant phages with approximately several hundred basepairs of matching phage sequence upstream and downstream of the insertion site to promote homologous recombination. NANOLUC® luciferase is inserted into a pCE104 Gram positive shuttle vector plasmid backbone with an upstream untranslated region containing a dedicated phage late gene promoter and Ribosomal Entry Site. pCE104.ElR.A511.NanoLuc.v2 was used to construct recombinants for the Pecentumviruses A511, LMA4 and LMA8. pCE104.HR.LP- ESl.NanoLuc was used to construct the Homburvirus LP-ES1. Each construct consisted of 500 bp of homologous sequence consisting of a fragment of the Major Capsid Protein gene (cps) followed by a late gene promoter, which was added in addition to the endogenous late gene promoter upstream of the major capsid protein in the phage genome, the luciferase gene, and approximately 258 bp of downstream matching sequence for homologous recombination for pCE104.HR.A51 LNanoLuc.v2 and 500 bp of downstream for pCE104.HR.LP-ESl.NanoLuc. All recombinants used a PlOOvirus late gene promoter instead of the T4 late gene promoter.

[0025] Figure 4 depicts a filter plate assay for detecting bacteria of interest using a modified bacteriophage according to an embodiment of the invention where bacteria and recombinant phage are incubated on filter plates and after generation of progeny bacteriophage the indicator protein is detected directly without removal of the incubation medium.

[0026] Figure 5 shows data from embodiments of a Listeria detection assays using recombinant bacteriophage specific for Listeria to detect Listeria in spiked sponges. Figure 5A shows detection of Listeria in sponges spiked at <1CFU spike/lOmL. Figure 5B shows detection of Listeria in sponges spiked at <1CFU spike/90mL.

[0027] Figure 6 shows data from embodiments of a Listeria detection assay using recombinant bacteriophage specific for Listeria to detect Listeria in environmental surface swab sponge samples.

[0028] Figure 7 depicts phage morphology visualized by transmission electron microscopy. Figure 7A depicts LPJPl’s large icosahedral head and long straight tail. Figure 7B depicts LPJPl’s contractile outer tail sheath.

[0029] Figure 8 depicts gel electrophoresis of PCR-amplified LPJP1 DNA. Flanking lanes 1 and 6 contain O’GeneRuler Ikb plus DNA ladder. Lanes 2 through 5 contain the PCR amplification of either native LPJP1 DNA (lanes 2 and 4) or TempliPhi -treated LPJP1 DNA (lanes 3 and 5) using either the Q5 DNA polymerase (lanes 2 and 3) or the uracil-tolerant Q5U DNA polymerase (lanes 4 and 5).

[0030] Figure 9 depicts plaque formation by LPJP1 on /.. grayi (ATCC 19120). LPJP1 was diluted, mixed with overnight culture and 0.5% semi-solid BHI agar, and poured evenly atop BHI agar plates. Plates were imaged after overnight incubation at 30 °C.

DETAILED DESCRIPTION OF THE INVENTION

[0031] Disclosed herein are compositions, methods and systems that demonstrate surprising sensitivity for detection of a microorganism of interest, such as Listeria spp., in test samples (e.g., biological, food, water, and environmental samples). Detection can be achieved in a shorter timeframe than was previously thought possible using genetically modified infectious agents in assays performed with minimal enrichment times during which microorganisms could potentially multiply. Also surprising is the success of using a potentially high multiplicity of infection (MOI), or high concentrations of plaque forming units (PFU), for incubation with a test sample. Such high phage concentrations (PFU/mL) were previously purported to be detrimental in bacterium detection assays, as they were purported to cause “lysis from without.” However, a high concentration of phage can facilitate finding, binding, and infecting a low number of target cells.

[0032] The compositions, methods, systems and kits of the invention may comprise infectious agents for use in detection of microorganisms such as Listeria spp. In certain embodiments, the invention may comprise a composition comprising a recombinant bacteriophage having an indicator gene inserted into a late gene region of the bacteriophage. In certain embodiments, expression of the indicator gene during bacteriophage replication following infection of a host bacterium results in production of a soluble indicator protein product. In certain embodiments, the indicator gene may be inserted into a late gene (i.e., class III) region of the bacteriophage. The bacteriophage can be derived from Listeria 5/?/?. -specific bacteriophage, or another wildtype or engineered bacteriophage. In some embodiments, the recombinant bacteriophage is constructed from at least one of LPJP1, LMA4, LMA8, A511, P70, LP-ES1, and LP-ES3 bacteriophages. [0033] In some embodiments, the compositions, methods, systems and kits of the invention may comprise a cocktail of at least one recombinant bacteriophage for use in detection of microorganisms such as Listeria spp.

[0034] In some aspects, the invention comprises a method for detecting a microorganism of interest. The method may use an infectious agent for detection of the microorganism of interest such as Listeria spp. For example, in certain embodiments, the microorganism of interest is Listeria spp. and the infectious agent is a bacteriophage that specifically infects a Listeria spp. Thus, in certain embodiments, the method may comprise detection of a bacterium of interest in a sample by incubating the sample with a recombinant bacteriophage that infects the bacterium of interest. In certain embodiments, the recombinant bacteriophage comprises an indicator gene. The indicator gene may, in certain embodiments, be inserted into a late gene region of the bacteriophage such that expression of the indicator gene during bacteriophage replication following infection of host bacteria results in production of an indicator protein product. The method may comprise detecting the indicator protein product, wherein positive detection of the indicator protein product indicates that the bacterium of interest is present in the sample. In some embodiments, the indicator protein is soluble.

[0035] In certain embodiments, the invention may comprise a system. The system may contain at least some of the compositions of the invention. Also, the system may comprise at least some of the components for performing the method. In certain embodiments, the system is formulated as a kit. Thus, in certain embodiments, the invention may comprise a system for rapid detection of a microorganism of interest such as Listeria spp. in a sample, comprising: A component for incubating the sample with an infectious agent specific for the microorganism of interest, wherein the infectious agent comprises an indicator moiety; and a component for detecting the indicator moiety. In yet other embodiments, the invention comprises software for use with the methods or systems.

[0036] Thus, some embodiments of the present invention solve a need by using bacteriophage-based methods for amplifying a detectable signal indicating the presence of bacteria. In certain embodiments as few as 10 bacteria are detected. The principles applied herein can be applied to the detection of a variety of microorganisms. Because of numerous binding sites for an infectious agent on the surface of a microorganism, the capacity to produce progeny during infection, and the potential for high level expression of an encoded indicator moiety, the infectious agent or an indicator moiety can be more readily detectable than the microorganism itself. In this way, embodiments of the present invention can achieve tremendous signal amplification from even a single infected cell.

[0037] Aspects of the present invention utilize the high specificity of binding agents that can bind to particular microorganisms, such as the binding component of infectious agents, as a means to detect and/or quantify the specific microorganism in a sample. In some embodiments, the present invention utilizes the high specificity of infectious agents such as bacteriophage.

[0038] In some embodiments, detection is achieved through an indicator moiety associated with the binding agent specific for the microorganism of interest. For example, an infectious agent may comprise an indicator moiety, such as a gene encoding a soluble indicator. In some embodiments the indicator may be encoded by the infectious agent, such as a bacteriophage, and the bacteriophage is designated an indicator phage.

[0039] Some embodiments of the invention disclosed and described herein utilize the discovery that a single microorganism is capable of binding specific recognition agents, such as phage. Following infection and replication of the phage, progeny phage may be detected via an indicator moiety expressed during phage replication. This principle allows amplification of indicator signal from one or a few cells based on specific recognition of microorganism surface receptors. For example, by exposing as few as 10 bacteria cells to a plurality of phage, thereafter allowing amplification of the phage and high-level expression of an encoded indicator gene product during replication, the indicator signal is amplified such that the bacteria are detectable.

[0040] Embodiments of the methods and systems of the invention can be applied to detection and quantification of a variety of microorganisms (e.g., bacteria) in a variety of circumstances, including but not limited to detection of pathogens from food, water, and commercial samples. The methods of the present invention provide high detection sensitivity and specificity rapidly. In some embodiments detection is possible within a single replication cycle of the bacteriophage, which is unexpected. Definitions

[0041] Unless otherwise defined herein, scientific and technical terms used in connection with the present invention shall have the meanings that are commonly understood by those of ordinary skill in the art. Further, unless otherwise required by context, singular terms shall include pluralities and plural terms shall include the singular. Generally, nomenclatures used in connection with, and techniques of, cell and tissue culture, molecular biology, immunology, microbiology, genetics and protein and nucleic acid chemistry and hybridization described herein are those well-known and commonly used in the art. Known methods and techniques are generally performed according to conventional methods well known in the art and as described in various general and more specific references that are discussed throughout the present specification unless otherwise indicated. Enzymatic reactions and purification techniques are performed according to manufacturer's specifications, as commonly accomplished in the art or as described herein. The nomenclatures used in connection with the laboratory procedures and techniques described herein are those well-known and commonly used in the art.

[0042] The following terms, unless otherwise indicated, shall be understood to have the following meanings:

[0043] As used herein, the terms “a”, “an”, and “the” can refer to one or more unless specifically noted otherwise.

[0044] The use of the term “or” is used to mean “and/or” unless explicitly indicated to refer to alternatives only or the alternatives are mutually exclusive, although the disclosure supports a definition that refers to only alternatives and “and/or.” As used herein “another” can mean at least a second or more.

[0045] Throughout this application, the term “about” is used to indicate that a value includes the inherent variation of error for the device, the method being employed to determine the value, or the variation that exists among samples.

[0046] The term “solid support” or “support” means a structure that provides a substrate and/or surface onto which biomolecules may be bound. For example, a solid support may be an assay well (i.e., such as a microtiter plate or multi-well plate), or the solid support may be a location on a filter, an array, or a mobile support, such as a bead or a membrane (e.g., a filter plate, latex particles, paramagnetic particles, or lateral flow strip).

[0047] The term “binding agent” refers to a molecule that can specifically and selectively bind to a second (i.e., different) molecule of interest. The interaction may be non-covalent, for example, as a result of hydrogen bonding, van der Waals interactions, or electrostatic or hydrophobic interactions, or it may be covalent. The term “soluble binding agent” refers to a binding agent that is not associated with (i.e., covalently or non-covalently bound) to a solid support.

[0048] As used herein, an “analyte” refers to a molecule, compound or cell that is being measured. The analyte of interest may, in certain embodiments, interact with a binding agent. As described herein, the term “analyte” may refer to a protein or peptide of interest. An analyte may be an agonist, an antagonist, or a modulator. Or, an analyte may not have a biological effect. Analytes may include small molecules, sugars, oligosaccharides, lipids, peptides, peptidomimetics, organic compounds and the like.

[0049] The term “detectable moiety” or “detectable biomolecule” or “reporter” or “indicator” or “indicator moiety” refers to a molecule that can be measured in a quantitative assay. For example, an indicator moiety may comprise an enzyme that may be used to convert a substrate to a product that can be measured. An indicator moiety may be an enzyme that catalyzes a reaction that generates bioluminescent emissions (e.g., luciferase). Or, an indicator moiety may be a radioisotope that can be quantified. Or, an indicator moiety may be a fluorophore. Or, other detectable molecules may be used.

[0050] As used herein, “bacteriophage” or “phage” includes one or more of a plurality of bacterial viruses. In this disclosure, the terms “bacteriophage” and “phage” include viruses such as mycobacteriophage (such as for TB and paraTB), mycophage (such as for fungi), mycoplasma phage, and any other term that refers to a virus that can invade living bacteria, fungi, mycoplasma, protozoa, yeasts, and other microscopic living organisms and uses them to replicate itself. Here, “microscopic” means that the largest dimension is one millimeter or less. Bacteriophages are viruses that have evolved in nature to use bacteria as a means of replicating themselves. A phage does this by attaching itself to a bacterium and injecting its DNA (or RNA) into that bacterium, and inducing it to replicate the phage hundreds or even thousands of times. This is referred to as phage amplification.

[0051] As used herein, “late gene region” refers to a region of a viral genome that is transcribed late in the viral life cycle. The late gene region typically includes the most abundantly expressed genes (e.g., structural proteins assembled into the bacteriophage particle). Late genes are synonymous with class III genes and include genes with structure and assembly functions. For example, the late genes (synonymous with class III,) are transcribed in phage T7, e.g., from 8 minutes after infection until lysis, class I (e.g., RNA polymerase) is early from 4-8 minutes, and class II from 6-15 minutes, so there is overlap in timing of II and III. A late promoter is one that is naturally located and active in such a late gene region.

[0052] As used herein, “culturing for enrichment” refers to traditional culturing, such as incubation in media favorable to propagation of microorganisms, and should not be confused with other possible uses of the word “enrichment,” such as enrichment by removing the liquid component of a sample to concentrate the microorganism contained therein, or other forms of enrichment that do not include traditional facilitation of microorganism propagation. Culturing for enrichment for periods of time may be employed in some embodiments of methods described herein.

[0053] As used herein “recombinant” refers to genetic (i.e., nucleic acid) modifications as usually performed in a laboratory to bring together genetic material that would not otherwise be found. This term is used interchangeably with the term “modified” herein.

[0054] As used herein “RLU” refers to relative light units as measured by a luminometer (e.g., GLOMAX® 96) or similar instrument that detects light. For example, the detection of the reaction between luciferase and appropriate substrate (e.g., NANOLUC® with NANO-GLO®) is often reported in RLU detected.

[0055] As used herein “time to results” refers to the total amount of time from beginning of sample incubation to generated result. Time to results does not include any confirmatory testing time. Data collection can be done at any time after a result has been generated. Samples

[0056] Each of the embodiments of the methods and systems of the invention can allow for the rapid detection and quantification of microbes in a sample. For example, methods according to the present invention can be performed in a shortened time period with superior results.

[0057] Bacterial cells detectable by the present invention include, but are not limited to, bacterial cells that are food or water borne pathogens.

[0058] Samples may be liquid, solid, or semi-solid. Samples may be swabs of solid surfaces. Samples may include environmental materials, such as water samples, or the filters from air samples or aerosol samples from cyclone collectors. Samples may be of vegetables, meat, fish, poultry, peanut butter, processed foods, powdered infant formula, powdered milk, teas, starches, eggs, milk, cheese, or other dairy products.

[0059] In some embodiments, samples may be used directly in the detection methods of the present invention, without preparation, concentration, or dilution. For example, liquid samples, including but not limited to, milk and juices, may be assayed directly. Samples may be diluted or suspended in solution, which may include, but is not limited to, a buffered solution or a bacterial culture medium. A sample that is a solid or semi-solid may be suspending in a liquid by mincing, mixing or macerating the solid in the liquid. A sample should be maintained within a pH range that promotes bacteriophage attachment to the host bacterial cell. A sample should also contain the appropriate concentrations of divalent and monovalent cations, including but not limited to Na ⁺ , Mg ²⁺ , and Ca ²⁺ . Preferably a sample is maintained at a temperature that maintains the viability of any pathogen cells contained within the sample.

[0060] In some embodiments of the detection assay, the sample is maintained at a temperature that maintains the viability of any pathogen cell present in the sample. For example, during steps in which bacteriophages are attaching to bacterial cells, it is preferable to maintain the sample at a temperature that facilitates bacteriophage attachment. During steps in which bacteriophages are replicating within an infected bacterial cell or lysing such an infected cell, it is preferable to maintain the sample at a temperature that promotes bacteriophage replication and lysis of the host. Such temperatures are at least about 25 degrees Celsius (C), more preferably no greater than about 35 degrees C, most preferably about 30 degrees C. [0061] Assays may include various appropriate control samples. For example, control samples containing no bacteriophages or control samples containing bacteriophages without bacteria may be assayed as controls for background signal levels.

Indicator Bacteriophage

[0062] As described in more detail herein, the compositions, methods, systems and kits of the invention may comprise infectious agents for use in detection of pathogenic microorganisms. In certain embodiments, the invention comprises a recombinant indicator bacteriophage, wherein the bacteriophage genome is genetically modified to include an indicator or reporter gene. In some embodiments, the invention may include a composition comprising a recombinant bacteriophage having an indicator gene incorporated into the genome of the bacteriophage.

[0063] A recombinant indicator bacteriophage can include a reporter or indicator gene. In certain embodiments of the infectious agent, the indicator gene does not encode a fusion protein. For example, in certain embodiments, expression of the indicator gene during bacteriophage replication following infection of a host bacterium results in a soluble indicator protein product. In certain embodiments, the indicator gene may be inserted into a late gene region of the bacteriophage. Late genes are generally expressed at higher levels than other phage genes, as they code for structural proteins. The late gene region may be a class III gene region and may include a gene for a major capsid protein.

[0064] Some embodiments include designing (and optionally preparing) a sequence for homologous recombination downstream of the major capsid protein gene. Other embodiments include designing (and optionally preparing) a sequence for homologous recombination upstream of the major capsid protein gene. In some embodiments, the sequence comprises a codon- optimized reporter gene preceded by an untranslated region. The untranslated region may include a phage late gene promoter and ribosomal entry site.

[0065] In some embodiments, an indicator bacteriophage is derived from Listeria-specific phage. In some embodiments, the selected wild-type bacteriophage or cocktail of wild-type bacteriophages is capable of infecting at least one target Listeria spp. In some embodiments, the wild-type bacteriophage is mutated to expand the host range of the wild-type bacteriophage. Listeria species are ubiquitous in the environment and are often found in water, sewage and soil. In some embodiments, the selected wild-type bacteriophage or cocktail of wild-type bacteriophages is capable of infecting one or more, two or more, or three or more target Listeria spp. In certain instances the target species of Listeria is selected from L. monocytogenes, L. ivanovii, L. innocua, and L. grayi. Listeria grayi is a Gram-positive bacterial species, consisting of two genetically related subspecies: L. grayi subsp. grayi and L. grayi subsp. murrayi. Although typically classified as non-pathogenic, L. grayi has been associated with severe disease in rare cases involving immunocompromised individuals (Todeschini, et al., A case of Listeria murray/grayi bacteremia in a patient with advanced Hodgkin's disease. Eur J Clin Microbiol Infect Dis 1998, 77, 808-810; Rapose, et al., Transpl Infect Dis 2008, 10, 434-436; Salimnia, et al., Listeria grayi: vancomycin-resistant, gram-positive rod causing bacteremia in a stem cell transplant recipient. Transpl Infect Dis 2010, 72, 526-528). L. grayi shares a number of important characteristics with the food-borne pathogen, L. monocytogenes, including motility and growth at refrigerated temperatures (Orsi, R.H.; Wiedmann, M. Characteristics and distribution of Listeria spp., including Listeria species newly described since 2009. Appl Microbiol Biotechnol 2016, 100, 5273-5287). These shared features have allowed this and other non-pathogenic Listeria species to serve as useful tools in food safety. One particular example of this can be seen in Listeria environmental monitoring programs (Tompkin, R.B. Control of Listeria monocytogenes in the food-processing environment. J Food Prot 2002, 65, 709-725). If any viable Listeria species are detected during sampling, preventative intervention allows the elimination of permissive growth conditions in an effort to preempt contamination with pathogenic species, particularly L. monocytogenes.

[0066] Hundreds of Listeria phages have been described over the years and the deficiency in lytic phage appears unique to the L. grayi species. For example, previous work developing a bacteriophage typing system for Listeria species revealed that none of the 16 typing phage could lyse Z. grayi (Loessner, M.J.; Busse, M. Appl Environ Microbiol 1990, 56, 1912-1918). Additionally, studies isolating Z/.s/c/va-specific phage from food processing plants found phage capable of lysing all tested Listeria species except for L. grayi (Kim, et al., Host ranges of Listeria-specific bacteriophages from the turkey processing plant environment in the United States. Appl Environ Microbiol 2008, 74, 6623-6630). The lack of reported lytic phages for this species could have indicated a unique phage resistance mechanism or simply imply that such a phage was incredibly rare or challenging to isolate. [0067] In some embodiments, the selected wild-type bacteriophage is from the Caudovirales order of phages. Caudovirales are an order of tailed bacteriophages with double-stranded DNA (dsDNA) genomes. Each virion of the Caudovirales order has an icosahedral head that contains the viral genome and a flexible tail. The Caudovirales order comprises five bacteriophage families: Myoviridae (long contractile tails), Siphoviridae (long non-contractile tails), Podoviridae (short non-contractile tails), Ackermannviridae , and Herelleviridae . The term myovirus can be used to describe any bacteriophage with an icosahedral head and a long contractile tail, which encompasses bacteriophages within both the Myoviridae and Herelleviridae families. In some embodiments, the selected wild-type bacteriophage is a member of the Myoviridae family such as, Listeria phage B054, Listeria phage LipZ5, Listeria phage PSU-VKH-LP041, and Listeria phage WIL-2. In other embodiments, the selected wild-type bacteriophage is a member of the family Herelleviridae. The genus Pecentumvirus, under the family Herelleviridae includes bacteriophages such as Listeria phage LMSP-25, Listeria phage LMTA-148, Listeria phage LMTA-34, Listeria phage LP-048, Listeria phage LP-064, Listeria phage LP-083-2, Listeria phage LP-125, Listeria virus P100, Listeria phage List-36, Listeria phage WIL-1, Listeria phage vB_LmoM_AG20, and Listeria virus A511. LMA4 and LMA8 are also likely in the genus pe centumvirus, under the family Herelleviridae . In other embodiments, the selected wild-type bacteriophage is LMA4 or LMA8.

[0068] In some embodiments, the host range of the selected wild-type bacteriophage is expanded prior to construction of the recombinant bacteriophage. For example, WT A511 bacteriophages are not capable of infecting the 3 A serotype of Listeria monocytogenes . In some embodiments, the host range of bacteriophage using the methods described in US 2020/0399614, which is incorporated in its entirety herein. For example, in some embodiments, a mutant bacteriophage with a an expanded host-range is produced using a method comprising: (i) preparing a series of first co-culture mixtures of varying ratios comprising a host bacterial strain and a target-host bacterial strain; (ii) adding a phage strain to each of the first co-culture mixtures; (iii) incubating the first co-culture mixtures and the phage strain under bacterial culture conditions; (iv) collecting a phage lysate from each of the plurality of first-co-cultures; (v) pooling the phage lysates from each of the plurality of first co-cultures; (vi) assaying phage lysates to determine if the bacteria host-range has expanded; and (vii) isolating a mutant phage with expanded host-range. In certain instances the selected wild-type bacteriophage is LP-ES3 (A511-3 A), which is derived from wild-type bacteriophage, A511, but has been adapted to be capable of infecting serotype 3 A of Listeria monocytogenes . In some embodiments, the mutant bacteriophage comprises a mutation in a gene encoding the tail receptor. In some embodiments, the mutation is a single nucleotide polymorphism. In certain instances, mutant bacteriophage comprising a mutation in a gene encoding the tail receptor are capable of infecting serotype 3 A of Listeria monocytogenes.

[0069] In still other embodiments, the selected wild-type bacteriophage is a member of the family Ackermannviridae . In still other embodiments, the selected wild-type bacteriophage is a member of the family Siphoviridae , which includes Listeria phages A006, Al 18, A500, B025, LP-026, LP-030-2, LP-030-3, LP-037, LP-101, LP-110, LP-114, P35, P40, P70, PSA, vB_LmoS_188, and vB_Lmos_293. In other embodiments, the selected wild-type bacteriophage is LP-ES1. LP-ES1 is also likely in the genus Hombiirgvirus. under the family Siphoviridae. LP- ES1 is capable of infecting L. innocua. In certain embodiments, the selected wild-type bacteriophage is capable of infecting L. innocua.

[0070] In some embodiments, the selected wild-type bacteriophage is a jumbo or giant bacteriophage. Jumbo phages are prokaryotic viruses with genomes greater than 200 kbp in length. Compared with smaller phage, jumbo phages are rarely described and the vast majority (greater than 95%) of these phages recognize Gram-negative bacteria, with only a few recognizing Gram-positive species, primarily within the genus Bacillus (Yuan, Y.; Gao, M. Jumbo Bacteriophages: An Overview. Front Microbiol 2017, 8, 403). The majority of identified jumbo phages belong to the order Caudovirales. They have a head with icosahedral symmetry and a tail. The majority of the genes in a jumbo phage are functionally unassigned. These phages are able to create highly complex virions compared to those of phages with smaller genomes. Some genomes have novel host infection strategies.

[0071] Many Listeria phages are not species-dependent but are specific for one or more serovars. Broad host range Listeria phage, such as A511, can infect multiple serovars by binding to conserved substituents of cell wall teichoic acids (WTAs). Other Gram-positive jumbo phage, such as PBS1 of Bacillus, appear to recognize active host flagella. L. grayi is the only motile species of the Listeria sensu lato group. Additionally, the flagellar antigens of L. grayi have previously been found to be unique compared to all other species. Although the regulation of flagella in L. grayi is poorly described, it is worth noting that flagellar expression in L. monocytogenes is typically suppressed at 37 °C. Thus, in some embodiments, the bacteriophage is specific for a flagellar antigen of a bacteria of interest. In certain instances, the bacteriophage is specific for a conserved substituent of WTAs of a bacteria of interest.

[0072] In some embodiments, an indicator bacteriophage is derived from /./.s/c/va-specific phage. An indicator bacteriophage may be constructed from a Pecentumvirus, Tequatravirus, Vil, Kuttervirus, Homburgvirus, LPJP1, LMTA-94, LMA4, LMA8, P70, LP-ES1, LP-ES3 or another bacteriophage having a genome with at least 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, or 99 % homology o Listeria phage LPJP1, LMTA-94, P70, T7, T7-like, T4, T4-like, Listeria spp. -specific bacteriophage, Vil, or Vil-like (Kuttervirus, per GenBank/NCBI) bacteriophages. In other embodiments, the selected wild-type bacteriophage is LPJP1, LP-ES1, LP-ES3, LMA4 or LMA8. In some embodiments, the indicator phage is derived from a bacteriophage that is highly specific for a particular pathogenic microorganism. The genetic modifications may avoid deletions of wild-type genes and thus the modified phage may remain more similar to the wild-type infectious agent than many commercially available phage. Environmentally derived bacteriophage may be more specific for bacteria that are found in the environment and as such, genetically distinct from phage available commercially.

[0073] In some embodiments, the recombinant bacteriophage is constructed using the WT bacteriophage LPJP1 (SEQ ID NO: 1). In certain embodiments recombinant bacteriophage is constructed using a WT bacteriophage having SEQ ID NO:1 or at least 95, 90, 85, 80, or 75% homology to SEQ ID NO: 1.

[0074] In another aspect of the invention, a cocktail composition comprises at least one type of recombinant bacteriophage. In some embodiments, the cocktail composition comprises at least one type of recombinant bacteriophage constructed from LPJP1, LMA4, LMA8, A511, P70, LP- ES1, and LP-ES3. In other embodiments, the cocktail composition comprises at least one type of recombinant bacteriophage constructed from LPJP1, LMA8, LP-ES1, and LP-ES3. In some embodiments, the bacteriophage cocktail is capable of infecting L. monocytogenes. In certain embodiments, the bacteriophage cocktail is capable of infecting at least 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, or 13 or more serovars of /.. monocytogenes. In some embodiments, the bacteriophage cocktail is capable of infecting at least one of serovars l/2a, l/2b, l/2c, 3a, 3b, 3c, 4a, 4b, 4c, 4d, 4e, 6a, and 6c of the species L. monocytogenes.

[0075] In some embodiments, the cocktail composition comprises ate leat one recombinant bacteriophage capable of infecting L. innocua. LP-ES1, likely in the genus Homburgvirus. under the family Siphoviridae, is capable of infecting L. innocua.

[0076] Although phages have been found for most Listeria species, phages targeting L. grayi have thus far remained elusive. In some embodiments, the bacteriophage cocktail, comprises a recombinant bacteriophage capable of detecting L. grayi. The L. grayi -specific phage LPJP1 was isolated from farm silage. TEM revealed that LPJP1 was morphologically similar to the dsDNA Myoviridae family, with a large icosahedral head, a long straight tail, and a contractile outer tail sheath (Figure 7A,B). LPJP1 is a jumbo phage displaying a genome with only limited homology to available viral DNA sequences. Jumbo phages are tailed bacteriophages with genomes larger than 200kbp having both a large phage virion and large genome size. Jumbo phages are difficult to isolate. Top hits by BLAST analysis were other jumbo phages, specifically those that infect another Gram-positive genus, Bacillus. Poor sequence homology among jumbo phages has been previously described and genome annotation is often underwhelming due to the significant occurrence of genes of unknown function. The paucity of jumbo phage in Gram-positive genera besides Bacillus has resulted in speculation that this could indicate a unique property of Bacillus or alternatively, that phage targeting other Gram-positive genera simply remained to be discovered. To date, only one example of a jumbo phage infecting a Gram-positive genus outside of Bacillus had been reported. The Staphylococcus phage S6, although not fully sequenced, was originally described as a giant myophage with an approximate genome size of 270 kbp.

Surprisingly, LPJP1 appears to not only be the first identified L. grayi phage, but also the first jumbo phage infecting the Listeria genus. In some embodiments, the phage is a jumbo phage. In certain instances, the jumbo phage is specific for Listeria. In some embodiments, the jumbo phage is specific for /.. grayi.

[0077] Moreover, phage genes thought to be nonessential may have unrecognized function. For example, an apparently nonessential gene may have an important function in elevating burst size such as subtle cutting, fitting, or trimming functions in assembly. Therefore, deleting genes to insert an indicator may be detrimental. Most phages can package DNA that is a few percent larger than their natural genome. Thus a bacteriophage with a larger genome size may be advantageous. In some embodiments, the bacteriophage is a jumbo bacteriophages. In some embodiments, the jumbo bacteriophage has a genome that is at least 200, 225, 250, 275, 300, 325, 350, 375, 400, 425, 450, 475, 500, 525, or 550 kbp in length.

[0078] In some instances, a jumbo bacteriophage may not be available for a particular bacteria of interest. With this consideration a smaller indicator gene may be a more appropriate choice for modifying a bacteriophage, especially one with a smaller genome. OpLuc and NANOLUC® proteins are only about 20 kDa (approximately 500-600 bp to encode), while FLuc is about 62 kDa (approximately 1,700 bp to encode). Moreover, the reporter gene should not be expressed endogenously by the bacteria (i.e., is not part of the bacterial genome), should generate a high signal to background ratio, and should be readily detectable in a timely manner. In some embodiments, the indicator gene is a luciferase. In other embodiments, the indicator gene is an active subunit of a luciferase. Promega’s NANOLUC® is a modified Oplophorus gracilirostris (deep sea shrimp) luciferase. In some embodiments, NANOLUC® combined with Promega’s NANO-GLO®, an imidazopyrazinone substrate (furimazine), can provide a robust signal with low background.

[0079] In some indicator phage embodiments, the indicator gene can be inserted into an untranslated region to avoid disruption of functional genes, leaving wild-type phage genes intact, which may lead to greater fitness when infecting non-lab oratory strains of bacteria. Additionally, including stop codons in all three reading frames may help to increase expression by reducing read-through, also known as leaky expression. This strategy may also eliminate the possibility of a fusion protein being made at low levels, which would manifest as background signal (e.g., luciferase) that cannot be separated from the phage.

[0080] An indicator gene may express a variety of biomolecules. The indicator gene is a gene that expresses a detectable product or an enzyme that produces a detectable product. For example, in one embodiment the indicator gene encodes a luciferase enzyme. Various types of luciferase may be used. In alternate embodiments, and as described in more detail herein, the luciferase is one of Oplophorus luciferase, Firefly luciferase, Lucia luciferase, Renilla luciferase, or an engineered luciferase. In some embodiments, the luciferase gene is derived from Oplophorus. In some embodiments, the indicator gene is a genetically modified luciferase gene, such as NANOLUC®.

[0081] Thus, in some embodiments, the present invention comprises a genetically modified bacteriophage comprising a non-bacteriophage indicator gene in the late (class III) gene region. In some embodiments, the non-native indicator gene is under the control of a late promoter. Using a viral late gene promoter ensures the reporter gene (e.g., luciferase) is not only expressed at high levels, like viral capsid proteins, but also does not shut down like endogenous bacterial genes or even early viral genes.

[0082] In some embodiments, the late promoter is a Pecentumvirus, Tequatravirus, Homburgvirus, or Kuttervirus promoter, or another phage promoter similar to that found in the selected wild-type phage, i.e., without genetic modification. The late gene region may be a class III gene region, and the bacteriophage may be derived from Listeria phage LMTA-94, P70, A511, LP-ES1, LP-ES3, LMA4, LMA8, Pecentumvirus, Tequatravirus, Homburgvirus, Kuttervirus, T7, T4, T4-like, Vil, Listeria spp. -specific bacteriophage, or another wild-type bacteriophage having a genome with at least 70, 75, 80, 85, 90 or 95% homology to LMTA-94, LMA4, LMA8, Pecentumvirus, Tequatravirus, Homburgvirus, Kuttervirus, T7, T4, Vil, or Listeria-specific bacteriophage. The Pecentumvirus late gene promoter is distinct from the T4 or Tequatravirus promoter, as it consists of not only the -10 region, but also a -35 region. This -35 region differs from the standard -35 region found in most bacterial promoters.

[0083] Genetic modifications to infectious agents may include insertions, deletions, or substitutions of a small fragment of nucleic acid, a substantial part of a gene, or an entire gene. In some embodiments, inserted or substituted nucleic acids comprise non-native sequences. A non- native indicator gene may be inserted into a bacteriophage genome such that it is under the control of a bacteriophage promoter. Thus, in some embodiments, the non-native indicator gene is not part of a fusion protein. That is, in some embodiments, a genetic modification may be configured such that the indicator protein product does not comprise polypeptides of the wildtype bacteriophage. In some embodiments, the indicator protein product is soluble. In some embodiments, the invention comprises a method for detecting a bacterium of interest comprising the step of incubating a test sample with such a recombinant bacteriophage. [0084] In some embodiments, expression of the indicator gene in progeny bacteriophage following infection of host bacteria results in a free, soluble protein product. In some embodiments, the non-native indicator gene is not contiguous with a gene encoding a structural phage protein and therefore does not yield a fusion protein. Unlike systems that employ a fusion of a detection moiety to the capsid protein (i.e., a fusion protein), some embodiments of the present invention express a soluble indicator or reporter (e.g., soluble luciferase). In some embodiments, the indicator or reporter is ideally free of the bacteriophage structure. That is, the indicator or reporter is not attached to the phage structure. As such, the gene for the indicator or reporter is not fused with other genes in the recombinant phage genome. This may greatly increase the sensitivity of the assay (down to a single bacterium), and simplify the assay, allowing the assay to be completed in two hours or less for some embodiments, as opposed to several hours due to additional purification steps required with constructs that produce detectable fusion proteins. Further, fusion proteins may be less active than soluble proteins due, e.g., to protein folding constraints that may alter the conformation of the enzyme active site or access to the substrate. If the concentration is 1,000 bacterial cells/mL of sample, for example, less than four hours of infection may be sufficient for the detection of the target bacterium.

[0085] Moreover, fusion proteins by definition limit the number of the moieties attached to subunits of a protein in the bacteriophage. For example, using a commercially available system designed to serve as a platform for a fusion protein would result in about 415 copies of the fusion moiety, corresponding to the about 415 copies of the gene 10B capsid protein in each T7 bacteriophage particle. Without this constraint, infected bacteria can be expected to express many more copies of the detection moiety (e.g., luciferase) than can fit on the bacteriophage. Additionally, large fusion proteins, such as a capsid-luciferase fusions, may inhibit assembly of the bacteriophage particle, thus yielding fewer bacteriophage progeny. Thus a soluble, nonfusion indicator gene product may be preferable.

[0086] In some embodiments, the indicator phage encodes a reporter, such as a detectable enzyme. The indicator gene product may generate light and/or may be detectable by a color change. Various appropriate enzymes are commercially available, such as alkaline phosphatase (AP), horseradish peroxidase (HRP), or luciferase (Luc). In some embodiments, these enzymes may serve as the indicator moiety. In some embodiments, Firefly luciferase is the indicator moiety. In some embodiments, Oplophorus luciferase is the indicator moiety. In some embodiments, NANOLUC® is the indicator moiety. Other engineered luciferases or other enzymes that generate detectable signals may also be appropriate indicator moieties.

[0087] In some embodiments, the use of a soluble detection moiety eliminates the need to remove contaminating parental phage from the lysate of the infected sample cells. With a fusion protein system, any bacteriophage used to infect sample cells would have the detection moiety attached, and would be indistinguishable from the daughter bacteriophage also containing the detection moiety. As detection of sample bacteria relies on the detection of a newly created (de novo synthesized) detection moiety, using fusion constructs requires additional steps to separate old (parental) moieties from newly created (daughter bacteriophage) moieties. This may be accomplished by washing the infected cells multiple times, prior to the completion of the bacteriophage life cycle, inactivating excess parental phage after infection by physical or chemical means, and/or chemically modifying the parental bacteriophage with a binding moiety (such as biotin), which can then be bound and separated (such as by Streptavidin-coated Sepharose beads). However, even with all these attempts at removal, parental phage can remain when a high concentration of parental phage is used to assure infection of a low number of sample cells, creating background signal that may obscure detection of signal from infected cell progeny phage.

[0088] By contrast, with the soluble detection moiety expressed in some embodiments of the present invention, purification of the parental phage from the final lysate is unnecessary, as the parental phage do not have any detection moiety attached. Thus any detection moiety present after infection must have been created de novo, indicating the presence of an infected bacterium or bacteria. To take advantage of this benefit, the production and preparation of parental phage may include purification of the phage from any free detection moiety produced during the production of parental bacteriophage in bacterial culture. Standard bacteriophage purification techniques may be employed to purify some embodiments of phage according to the present invention, such as sucrose density gradient centrifugation, cesium chloride isopycnic density gradient centrifugation, HPLC, size exclusion chromatography, and dialysis or derived technologies (such as Amicon brand concentrators - Millipore, Inc.). Cesium chloride isopycnic ultracentrifugation can be employed as part of the preparation of recombinant phage of the invention, to separate parental phage particles from contaminating luciferase protein produced upon propagation of the phage in the bacterial host. In this way, the parental recombinant bacteriophage of the invention is substantially free of any luciferase generated during production in the bacteria. Removal of residual luciferase present in the phage stock can substantially reduce background signal observed when the recombinant bacteriophage are incubated with a test sample.

[0089] In some embodiments of modified bacteriophage, the late promoter (class III promoter, e.g., from Pecentumvirus, Homburgvirus, T7, T4, Vil, or LMA4/8) has high affinity for RNA polymerase of the same bacteriophage that transcribes genes for structural proteins assembled into the bacteriophage particle. These proteins are the most abundant proteins made by the phage, as each bacteriophage particle comprises dozens or hundreds of copies of these molecules. The use of a viral late promoter can ensure optimally high level of expression of the luciferase detection moiety. The use of a late viral promoter derived from, specific to, or active under the original wild-type bacteriophage the indicator phage is derived from (e.g., a Pecentumvirus, Homburgvirus, T4, T7, Vil, or LMA4/8 late promoter with a Pecentumvirus, T4, T7-, Vil-, or LMA-based system) can further ensure optimal expression of the detection moiety. The use of a standard bacterial (non-viral/non-bacteriophage) promoter may in some cases be detrimental to expression, as these promoters are often down-regulated during bacteriophage infection (in order for the bacteriophage to prioritize the bacterial resources for phage protein production). Thus, in some embodiments, the phage is preferably engineered to encode and express at high level a soluble (free) indicator moiety, using a placement in the genome that does not limit expression to the number of subunits of a phage structural component.

[0090] Compositions of the invention may comprise one or more wild-type or genetically modified infectious agents (e.g., bacteriophages) and one or more indicator genes. In some embodiments, compositions can include cocktails of different indicator phages that may encode and express the same or different indicator proteins. In some embodiments, the cocktail of bacteriophage comprises at least two different types of recombinant bacteriophages. Methods of Preparing Indicator Bacteriophage

[0091] Embodiments of methods for making indicator bacteriophage begin with selection of a wild-type bacteriophage for genetic modification. Some bacteriophage are highly specific for a target bacterium. This presents an opportunity for highly specific detection.

[0092] Thus, the methods of the present invention utilize the high specificity of binding agents, associated with infectious agents that recognize and bind to a particular microorganism of interest as a means to amplify a signal and thereby detect low levels of a microorganism (e.g., a single microorganism) present in a sample. For example, infectious agents (e.g., bacteriophage) specifically recognize surface receptors of particular microorganisms and thus specifically infect those microorganisms. As such, these infectious agents may be appropriate binding agents for targeting a microorganism of interest.

[0093] Some embodiments of the invention utilize the specificity of binding and high-level genetic expression capacity of recombinant bacteriophage for rapid and sensitive targeting to infect and facilitate detection of a bacterium of interest. In some embodiments, a Listeria- specific bacteriophage is genetically modified to include a reporter gene. In some embodiments the late gene region of a bacteriophage is genetically modified to include a reporter gene. In some embodiments, a reporter gene is positioned downstream of the major capsid gene. In other embodiments, a reporter gene is positioned upstream of the major capsid gene. In some embodiments, the inserted genetic construct further comprises its own exogenous, dedicated promoter to drive expression of the indicator gene. The exogenous promoter is in addition to any endogenous promoter in the phage genome. As bacteriophage produce polycistronic mRNA transcripts, only a single promoter is required upstream of the first gene/cistron in the transcript. Conventional recombinant constructs only use the endogenous bacteriophage promoter to drive inserted genes. In contrast, addition of an additional promoter upstream of the reporter gene and ribosomal binding site may increase gene expression by acting as a secondary initiation site for transcription. The complicated and compact genomes of viruses often have overlapping genes in different frames, sometimes in two different directions.

[0094] Some embodiments of methods for preparing a recombinant indicator bacteriophage include selecting a wild-type bacteriophage that specifically infects a target pathogenic bacterium such as Listeria spp.; preparing a homologous recombination plasmid/vector that comprises an indicator gene; transforming the homologous recombination plasmid/vector into target pathogenic bacteria; infecting the transformed target pathogenic bacteria with the selected wild-type bacteriophage, thereby allowing homologous recombination to occur between the plasmid/vector and the bacteriophage genome; and isolating a particular clone of recombinant bacteriophage.

[0095] Various methods for designing and preparing a homologous recombination plasmid are known. Various methods for transforming bacteria with a plasmid are known, including heatshock, F pilus-mediated bacterial conjugation, electroporation, and other methods. Various methods for isolating a particular clone following homologous recombination are also known. Some method embodiments described herein utilize particular strategies.

[0096] Thus, some embodiments of methods for preparing indicator bacteriophage include the steps of selecting a wild-type bacteriophage that specifically infects a target pathogenic bacterium; determining the natural sequence in the late region of the genome of the selected bacteriophage; annotating the genome and identifying the major capsid protein gene of the selected bacteriophage; designing a sequence for homologous recombination adjacent to the major capsid protein gene, wherein the sequence comprises a codon-optimized reporter gene; incorporating the sequence designed for homologous recombination into a plasmid/vector; transforming the plasmid/vector into target pathogenic bacteria; selecting for the transformed bacteria; infecting the transformed bacteria with the selected wild-type bacteriophage, thereby allowing homologous recombination to occur between the plasmid and the bacteriophage genome; determining the titer of the resulting recombinant bacteriophage lysate; and performing a limiting dilution assay to enrich and isolate the recombinant bacteriophage. Some embodiments comprise further repeating the limiting dilution and titer steps, following the first limiting dilution assay, as needed until the recombinant bacteriophage represent a detectable fraction of the mixture. For example, in some embodiments the limiting dilution and titer steps can be repeated until at least 1/30 of the bacteriophage in the mixture are recombinant before isolating a particular clone of recombinant bacteriophage. A ratio of 1 :30 recombinant:wild-type is expected, in some embodiments, to yield an average of 3.2 transducing units (TU) per 96 plaques (e.g., in a 96-well plate). The initial ratio of recombinant to wild-type phage may be determined by performing limiting dilution assays based on the TCID50 (tissue culture infectious dose 50%) as previously described in U.S. App. No. 15/409,258. By Poisson distribution, a 1 :30 ratio generates a 96% chance of observing at least one TU somewhere in the 96 wells.

[0097] Figure 1 depicts a schematic representation of the genomic structure of a recombinant indicator bacteriophage of the invention. For the embodiment depicted in Figure 1, the detection moiety is encoded by a luciferase gene 100 inserted within the late (class III) gene region 110, which is expressed late in the viral life cycle. Late genes are generally expressed at higher levels than other phage genes, as they code for structural proteins. Thus, in the embodiment of the recombinant phage depicted in Figure 1, the indicator gene (i.e., luciferase) is inserted into the late gene region, just after the gene for major capsid protein (cps) 120, and is a construct comprising the luciferase gene 100. In some embodiments, the construct depicted in Figure 1 may include stop codons in all 3 reading frames to ensure luciferase is not incorporated into the cps gene product through creation of a fusion protein. Also as depicted in Figure 1, the construct may comprise an additional, dedicated late promoter 130 to drive transcription and expression of the luciferase gene. The construct also comprises a ribosome binding site (RBS) 140. This construct ensures soluble luciferase is produced such that expression is not limited to the number of capsid proteins inherent in the phage display system.

[0098] As noted herein, in certain embodiments, it may be preferred to utilize infectious agents that have been isolated from the environment for production of the infectious agents of the invention. In this way, infectious agents that are specific to naturally derived microorganisms may be generated.

[0099] For example, Figure 2 shows the genome of bacteriophage LMA4, a wild-type bacteriophage that specifically infects Listeria spp. As discussed in the Examples, the Major Capsid Protein (cps) 240 and various other structural genes are within the late gene region 210, consisting of structural genes, which code for virion proteins. Genes coding for tRNA 220 represent genomic sequence adjacent to, but outside of the late gene region. A hypothetical gene homologous to the putative prohead protease of Listeria phage LMTA-94 230 is upstream of cps 240, consisting of structural genes, which code for virion proteins. Other late genes depicted are homologs to Listeria phage LMTA-94’s putative Major Capsid Protein (cps) 240, followed by a transcriptional terminator 250, and a homolog to Listeria phage LMTA-94 Tail Sheath Protein (tsh) 260. As these virion proteins are expressed at a very high level, any genes inserted into this region can be expected to have similar expression levels, as long as late gene promoters and/or other similar control elements are used.

[0100] There are numerous known methods and commercial products for preparing plasmids. For example, PCR, site-directed mutagenesis, restriction digestion, ligation, cloning, and other techniques may be used in combination to prepare plasmids. Synthetic plasmids can also be ordered commercially (e.g., GeneWiz). Cosmids can also be employed, or the CRISPR/CAS9 system could be used to selectively edit a bacteriophage genome. Some embodiments of methods of preparing a recombinant indicator bacteriophage include designing a plasmid that can readily recombine with the wild-type bacteriophage genome to generate recombinant genomes. In designing a plasmid, some embodiments include addition of a codon-optimized reporter gene, such as a luciferase gene. Some embodiments further include addition of elements into the upstream untranslated region. For example, in designing a plasmid to recombine with the Listeria -specific bacteriophage genome, an upstream untranslated region can be added between the sequence encoding the C-terminus of the gp23 / Major Capsid Protein and the start codon of the NANOLUC® reporter gene. The untranslated region can include a promoter, such as a T4, Tequatravirus, Homburgvirus, T7, T7-like, Pecentumvirus, Listeria-specific bacteriophage, Vil, or Kuttervirus promoter. The untranslated region can also include a Ribosomal Entry / Binding Site (RBS), also known as a “Shine-Dalgamo Sequence” with bacterial systems. Either or both of these elements, or other untranslated elements, can be embedded within a short upstream untranslated region made of random sequences comprising about the same GC content as rest of the phage genome. The random region should not include an ATG sequence, as that will act as a start codon.

[0101] The compositions of the invention may comprise various infectious agents and/or indicator genes. For example, Figure 3 shows a homologous recombination plasmid construct used in making the indicator phage specific for Listeria spp. Constructs were made and used in recombination with Listeria spp. phage LMA4, Listeria spp. phage LMA8, Listeria spp. phage LP-ES3, Listeria spp. phage LP-ES1 or other Listeria- specific phages to generate recombinant bacteriophage of the invention. The construct in Figure 3 shows a general schematic for the recombination plasmid used for homologous recombination insertion of the NANOLUC® luciferase into both Listeria spp. Pecentumvirus phages LMA4 and LMA8, each with 500 bp of upstream and downstream homologous sequence: homologous recombination plasmid pCE104.HR.ListeriaPhage.NANOLUC.v2. P ecentumvirus ,NANOLUC.v2 and the recombination plasmid used for homologous recombination insert of the NANOLUC® luciferase into Listeria spp. Homburgvirus phage LP-ES1, pCE104.HR.LP-ESl.NanoLuc

[0102] In certain embodiments a plasmid is designated pCE l 04.HR.Pecentumvirus.NanoLuc.v2. The detection/indicator moiety is encoded by the NANOLUC® reporter gene 300. The insert, represented by the series of rectangles, is in the Gram positive shuttle vector, pCE104 310. The upstream homologous recombination region consists of 500bp of the major capsid protein C-terminal fragment 320. A f ecentumvirus late promoter consensus sequence & Shine-Dalgarno Ribosomal Entry /Binding Site within the 5’ untranslated region 330. The codon-optimized NANOLUC® reporter gene 300 follows immediately after. The endogenous transcriptional terminator comes next, along with the untranslated region (UTR) and hypothetical protein N-Terminal fragment consisting of the downstream homologous recombination 340 are at the end of the Homologous Recombination region.

[0103] The Major Capsid Protein fragment is a part of a structural gene that encodes a virion protein. As these virion proteins are expressed at a very high level, any genes inserted into this region can be expected to have similar expression levels, as long as late gene promoters and/or other similar control elements are used.

[0104] In some embodiments, indicator phage according to the invention comprise Listeria- specific bacteriophage genetically engineered to comprise a reporter gene such as a luciferase gene. For example, an indicator phage can be Listeria spp. -specific bacteriophage wherein the genome comprises the sequence of the NANOLUC® gene. A recombinant Listeria-specific NANOLUC® bacteriophage genome may further comprise a consensus promoter of P ecentumvirus, T4, T7, Listeria-specific, Vil, LMA4, or LMA8 bacteriophage or another late promoter. In further embodiments, the promoter is an exogenous promoter. Insertion of an exogenous promoter to drive expression of an indicator gene is advantageous in that expression is not limited by the expression of other phage proteins (e.g., the major capsid protein).

[0105] Thus, in the embodiment of the recombinant phage generated as a result of the recombination, the indicator gene (i.e., NANOLUC®) is inserted into the late gene region, just downstream of the gene encoding the major capsid protein, and thus creates recombinant bacteriophage genomes comprising the NANOLUC® gene. The construct may additionally comprise the consensus promoter of Listeria phage LMTA-94, T4, T7, Listeria-specific bacteriophage, Vil, or another late promoter or another suitable promoter to drive transcription and expression of the luciferase gene. The construct may also comprise a composite untranslated region synthesized from several UTRs. This construct ensures soluble luciferase is produced such that expression is not limited to the number of capsid proteins inherent in the phage display system.

[0106] Recombinant phage generated by homologous recombination of a plasmid designed for recombination with the wild-type phage genome can be isolated from a mixture comprising a very small percentage (e.g., 0.005%) of total phage genomes. Following isolation, large scale production may be performed to obtain high titer recombinant indicator phage stocks appropriate for use in the Listeria spp. detection assay. Furthermore, cesium chloride isopycnic density gradient centrifugation may be used to separate phage particles from contaminating luciferase protein to reduce background.

[0107] NANOLUC®-expressing phage have repeatedly been found to exhibit impressive diagnostic sensitivity and robust signal production across multiple genera. Some jumbo phages have recently been described to form a novel nucleus-like proteinaceous shell upon infection, which protects phage DNA from host defense mechanisms and could conceivably interfere with genetic engineering. Despite this possibility, a NANOLUC®-expressing recombinant, LPJP1.NL was successfully generated using standard homologous recombination methods. LPJP1.NL produced substantial RLU from limited bacterial burdens without enrichment, requiring only a single log phase L. grayi bacterium to yield a detectable signal after a 4 h infection. As expected, signal increased proportionally with bacterial burden. Overall, LPJP1.NL is both the first jumbo phage reporter and the first phage reporter capable of detecting L. grayi. The success of LPJP1.NL highlights the untapped potential of jumbo phage in phage-based diagnostics.

Methods of Using Infectious Agents for Detecting Listeria spp. [0108] As noted herein, in certain embodiments, the invention may comprise methods of using infectious particles for detecting microorganisms. The methods of the invention may be embodied in a variety of ways.

[0109] In an embodiment, the invention may comprise a method for detecting a bacterium of interest in a sample comprising the steps of: incubating the sample with bacteriophage that infects the bacterium of interest, wherein the bacteriophage comprises an indicator gene such that expression of the indicator gene during bacteriophage replication following infection of the bacterium of interest results in production of a soluble indicator protein product; and detecting the indicator protein product, wherein positive detection of the indicator protein product indicates that the bacterium of interest is present in the sample. In certain instances, the invention comprises a method for detecting Listeria spp. in a sample comprising: incubating the sample with a cocktail composition comprising at least one Listeria-specific recombinant bacteriophage; and detecting an indicator protein product produced by the recombinant bacteriophage, wherein positive detection of the indicator protein product indicates that Listeria spp. is present in the sample.

[0110] In certain instances, the recombinant bacteriophage or cocktail of recombinant bacteriophages are capable of detecting one or more target species of Listeria. In some embodiments, the target species of Listeria is selected from L. monocytogenes, L. ivanovii, L. innocua, and L. grayi. In certain embodiments, the bacteriophage or cocktail of recombinant bacteriophages is capable of infecting at least 1, 2, 3, 4, 5, 6, or 7 or more serovars of L. monocytogenes. In some embodiments, the bacteriophage cocktail is capable of infecting at least one of serovars l/2a, l/2b, l/2c, 3a, 3b, 3c, 4d, 4d, 4e, and 7 of the species L. monocytogenes.

[0111] In some embodiments, at least one type of recombinant bacteriophage is constructed from LMA4, LMA8, A511, P70, LP-ES1, and LP-ES3. In other embodiments, at least one type of recombinant bacteriophage is constructed from LMA8, LP-ES1, and LP-ES3. In embodiments, the recombinant bacteriophage is cpable of infecting one or more of L. innocua, L. grayi, L. monocytogenes serovar 3 A.

[0112] In certain embodiments, the assay may be performed to utilize a general concept that can be modified to accommodate different sample types or sizes and assay formats. Embodiments employing recombinant bacteriophage of the invention (i.e., indicator bacteriophage) may allow rapid detection of specific bacterial strains such as Listeria spp., with total assay times under 1.5, 2.0, 2.5, 3.0, 3.5, 4.0, 4.5, 5.0, 5.5, 6.0, 6.5, 7.0, 7.5, 8.0, 8.5, 9.0, 9.5, 10.0, 10.5, 11.0, 11.5, 12, 12.5, 13.0, 13.5, 14.0, 14.5, 15.0, 15.5, 16.0, 16.5, 17.0, 17.5, 18.0, 18.5, 19.0, 19.5, 20.0, 21.0, 21.5 22.0, 22.5, 23.0, 23.5, 24.0, 24.5 25.0, 25.5, or 26.0 hours, depending on the sample type, sample size, and assay format. For example, the amount of time required may be somewhat shorter or longer depending on the strain of bacteriophage and the strain of bacteria to be detected in the assay, type and size of the sample to be tested, conditions required for viability of the target, complexity of the physical/chemical environment, and the concentration of “endogenous” non-target bacterial contaminants.

[0113] The bacteriophage (e.g., T7, T4,P70 P100, A511, LP-ES3, LP-ES1, LMA4 or LMA8 phage) may be engineered to express a soluble luciferase during replication of the phage. Expression of luciferase is driven by a viral capsid promoter (e.g., the bacteriophage Pecentumvirus or T4 late promoter), yielding high expression. Parental phage are prepared such that they are free of luciferase, so the luciferase detected in the assay must come from replication of progeny phage during infection of the bacterial cells. Thus, there is generally no need to separate out the parental phage from the progeny phage.

[0114] Figure 4 depicts a filter plate assay for detecting Listeria using a modified bacteriophage according to an embodiment of the invention. Briefly, samples 416 that include a bacterium of interest 418 may be added to wells 402 of a multi-well filter plate 404 and spun 406 to concentrate the samples by removal of liquid from the sample. Genetically modified phage 420 are added to wells and incubated with additional media added for enough time sufficient for adsorption 408 followed by infection of target bacteria and advancement of the phage life cycle 410 (e.g., ~ 240 minutes). Finally, luciferase substrate is added and reacts with any luciferase present 424. The resulting emission is measured in a luminometer 414 which detects luciferase activity 426.

[0115] In some embodiments, enrichment of bacteria in the sample is not needed prior to testing. In some embodiments, the sample may be enriched prior to testing by incubation in conditions that encourage growth. In such embodiments, the enrichment period can be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, or 24 hours or longer, depending on the sample type and size. [0116] In some embodiments, the indicator bacteriophage comprises a detectable indicator moiety, and infection of a single pathogenic cell (e.g., bacterium) can be detected by an amplified signal generated via the indicator moiety. Thus the method may comprise detecting an indicator moiety produced during phage replication, wherein detection of the indicator indicates that the bacterium of interest is present in the sample.

[0117] In an embodiment, the invention may comprise a method for detecting a bacterium of interest in a sample comprising the steps of: incubating the sample with a recombinant bacteriophage that infects the bacterium of interest, wherein the recombinant bacteriophage comprises an indicator gene inserted into a late gene region of the bacteriophage such that expression of the indicator gene during bacteriophage replication following infection of host bacteria results in production of a soluble indicator protein product; and detecting the indicator protein product, wherein positive detection of the indicator protein product indicates that the bacterium of interest is present in the sample. In some embodiments, the amount of indicator moiety detected corresponds to the amount of the bacterium of interest present in the sample.

[0118] As described in more detail herein, the methods and systems of the invention may utilize a range of concentrations of parental indicator bacteriophage to infect bacteria present in the sample. In some embodiments the indicator bacteriophage are added to the sample at a concentration sufficient to rapidly find, bind, and infect target bacteria that are present in very low numbers in the sample, such as ten cells. In some embodiments, the phage concentration can be sufficient to find, bind, and infect the target bacteria in less than one hour. In other embodiments, these events can occur in less than two hours, or less than three hours, or less than four hours, following addition of indicator phage to the sample. For example, in certain embodiments, the bacteriophage concentration for the incubating step is greater than 1 x 10 ⁵ PFU/mL, greater than 1 x 10 ⁶ PFU/mL, or greater than 1 x 10 ⁷ PFU/mL.

[0119] In certain embodiments, the recombinant infectious agent may be purified so as to be free of any residual indicator protein that may be generated upon production of the infectious agent stock. Thus, in certain embodiments, the recombinant bacteriophage may be purified using cesium chloride isopycnic density gradient centrifugation prior to incubation with the sample. When the infectious agent is a bacteriophage, this purification may have the added benefit of removing bacteriophage that do not have DNA (i.e., empty phage or “ghosts”). [0120] In some embodiments of the methods of the invention, the microorganism may be detected without any isolation or purification of the microorganisms from a sample. For example, in certain embodiments, a sample containing one or a few microorganisms of interest may be applied directly to an assay container such as a spin column, a microtiter well, or a filter and the assay is conducted in that assay container. Various embodiments of such assays are disclosed herein.

[0121] Aliquots of a test sample may be distributed directly into wells of a multi-well plate, indicator phage may be added, and after a period of time sufficient for infection, a lysis buffer may be added as well as a substrate for the indicator moiety (e.g., luciferase substrate for a luciferase indicator) and assayed for detection of the indicator signal. Some embodiments of the method can be performed on filter plates. Some embodiments of the method can be performed with or without concentration of the sample before infection with indicator phage.

[0122] For example, in many embodiments, multi -well plates are used to conduct the assays. The choice of plates (or any other container in which detecting may be performed) may affect the detecting step. For example, some plates may include a colored or white background, which may affect the detection of light emissions. Generally speaking, white plates have higher sensitivity but also yield a higher background signal. Other colors of plates may generate lower background signal but also have a slightly lower sensitivity. Additionally, one reason for background signal is the leakage of light from one well to another, adjacent well. There are some plates that have white wells but the rest of the plate is black. This allows for a high signal inside the well but prevents well-to-well light leakage and thus may decrease background. Thus the choice of plate or other assay vessel may influence the sensitivity and background signal for the assay.

[0123] Methods of the invention may comprise various other steps to increase sensitivity. For example, as discussed in more detail herein, the method may comprise a step for washing the captured and infected bacterium, after adding the bacteriophage but before incubating, to remove excess parental bacteriophage and/or luciferase or other reporter protein contaminating the bacteriophage preparation.

[0124] In some embodiments, detection of the microorganism of interest may be completed without the need for culturing the sample as a way to increase the population of the microorganisms. For example, in certain embodiments the total time required for detection is less than 28.0 hours, 27.0 hours, 26.0 hours, 25.0 hours, 24.0 hours, 23.0 hours, 22.0 hours, 21.0 hours, 20.0 hours, 19.0 hours, 18.0 hours, 17.0 hours, 16.0 hours, 15.0 hours, 14.0 hours, 13.0 hours, 12.0 hours, 11.0 hours, 10.0 hours, 9.0 hours, 8.0 hours, 7.0 hours, 6.0 hours, 5.0 hours, 4.0 hours, 3.0 hours, 2.5 hours, 2.0 hours, 1.5 hours, or less than 1.0 hour. Minimizing time to result is critical in food and environmental testing for pathogens.

[0125] In contrast to assays known in the art, the method of the invention can detect individual microorganisms. Thus, in certain embodiments, the method may detect as few as 10 cells of the microorganism present in a sample. For example, in certain embodiments, the recombinant bacteriophage is highly specific for Listeria spp. In an embodiment, the recombinant bacteriophage can distinguish Listeria spp. in the presence of other types of bacteria. In certain embodiments, the recombinant bacteriophage can be used to detect a single bacterium of the specific type in the sample. In certain embodiments, the recombinant bacteriophage detects as few as 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 30, 40, 50, 60, 70, 80, 90, or 100 of the specific bacteria in the sample.

[0126] Thus, aspects of the present invention provide methods for detection of microorganisms in a test sample via an indicator moiety. In some embodiments, where the microorganism of interest is a bacterium, the indicator moiety may be associated with an infectious agent such as an indicator bacteriophage. The indicator moiety may react with a substrate to emit a detectable signal or may emit an intrinsic signal (e.g., fluorescent protein). In some embodiments, the detection sensitivity can reveal the presence of as few as 50, 40, 30, 20, 10, 5, or 2 cells of the microorganism of interest in a test sample. In some embodiments, even a single cell of the microorganism of interest may yield a detectable signal. In some embodiments, the bacteriophage is a Pecentumvirus, Tequatravirus, Homburgvirus, or Kuttervirus bacteriophage. In some embodiments, the recombinant bacteriophage is derived from Listeria- specific bacteriophage. In certain embodiments, a recombinant /./.s/c/va-specific bacteriophage is highly specific for Listeria spp.

[0127] In some embodiments, the indicator moiety encoded by the infectious agent may be detectable during or after replication of the infectious agent. Many different types of detectable biomolecules suitable for use as indicator moieties are known in the art, and many are commercially available. In some embodiments the indicator phage comprises an enzyme, which serves as the indicator moiety. In some embodiments, the genome of the indicator phage is modified to encode a soluble protein. In some embodiments, the indicator phage encodes a detectable enzyme. The indicator may emit light and/or may be detectable by a color change in an added substrate. Various appropriate enzymes are commercially available, such as alkaline phosphatase (AP), horseradish peroxidase (HRP), or luciferase (Luc). In some embodiments, these enzymes may serve as the indicator moiety. In some embodiments, Firefly luciferase is the indicator moiety. In some embodiments, Oplophorus luciferase is the indicator moiety. In some embodiments, NANOLUC® is the indicator moiety. Other engineered luciferases or other enzymes that generate detectable signals may also be appropriate indicator moieties.

[0128] Thus, in some embodiments, the recombinant bacteriophage of the methods, systems or kits is prepared from wild-type Listeria-specific bacteriophage. In some embodiments, the indicator gene encodes a protein that emits an intrinsic signal, such as a fluorescent protein (e.g., green fluorescent protein or others). The indicator may emit light and/or may be detectable by a color change. In some embodiments, the indicator gene encodes an enzyme (e.g., luciferase) that interacts with a substrate to generate signal. In some embodiments, the indicator gene is a luciferase gene. In some embodiments, the luciferase gene is one of Oplophorus luciferase, Firefly luciferase, Renilla luciferase, External Gaussia luciferase, Lucia luciferase, or an engineered luciferase such as NANOLUC®, Rluc8.6-535, or Orange Nano-lantern.

[0129] Detecting the indicator may include detecting emissions of light. In some embodiments, a luminometer may be used to detect the reaction of indicator (e.g., luciferase) with a substrate. The detection of RLU can be achieved with a luminometer, or other machines or devices may also be used. For example, a spectrophotometer, CCD camera, or CMOS camera may detect color changes and other light emissions. Absolute RLU are important for detection, but the signal to background ratio also needs to be high (e.g., > 2.0, > 2.5, or > 3.0) in order for single cells or low numbers of cells to be detected reliably.

[0130] In some embodiments, the indicator phage is genetically engineered to contain the gene for an enzyme, such as a luciferase, which is only produced upon infection of bacteria that the phage specifically recognizes and infects. In some embodiments, the indicator moiety is expressed late in the viral life cycle. In some embodiments, as described herein, the indicator is a soluble protein (e.g., soluble luciferase) and is not fused with a phage structural protein that limits its copy number.

[0131] Thus in some embodiments utilizing indicator phage, the invention comprises a method for detecting a microorganism of interest comprising the steps of capturing at least one sample bacterium; incubating the at least one bacterium with a plurality of indicator phage; allowing time for infection and replication to generate progeny phage and express soluble indicator moiety; and detecting the progeny phage, or preferably the indicator, wherein detection of the indicator demonstrates that the bacterium is present in the sample.

[0132] For example, in some embodiments the test sample bacterium may be captured by binding to the surface of a plate, or by filtering the sample through a bacteriological filter (e.g., 0.45 pm pore size spin filter or plate filter). In an embodiment, the infectious agent (e.g., indicator phage) is added in a minimal volume to the captured sample directly on the filter. In an embodiment, the microorganism captured on the filter or plate surface is subsequently washed one or more times to remove excess unbound infectious agent. In an embodiment, a medium (e.g., Luria-Bertani (LB) Broth, Buffered Peptone Water (BPW) or Tryptic Soy Broth or Tryptone Soy Broth (TSB), Brain Heart Infusion (BHI) Buffered Listeria Enrichment Broth (BLEB) University of Vermont (UVM) Broth, or Fraser Broth) may be added for further incubation time, to allow replication of bacterial cells and phage and high-level expression of the gene encoding the indicator moiety. However, a surprising aspect of some embodiments of testing assays is that the incubation step with indicator phage only needs to be long enough for a single phage life cycle. The amplification power of using bacteriophage was previously thought to require more time, such that the phage would replicate for several cycles. A single replication cycle of indicator phage can be sufficient to facilitate sensitive and rapid detection according to some embodiments of the present invention.

[0133] In some embodiments, aliquots of a test sample comprising bacteria may be applied to a spin column and after infection with a recombinant bacteriophage and an optional washing to remove any excess bacteriophage, the amount of soluble indicator detected will be proportional to the amount of bacteriophage that are produced by infected bacteria.

[0134] Soluble indicator (e.g., luciferase) released into the surrounding liquid upon lysis of the bacteria may then be measured and quantified. In an embodiment, the solution is spun through the filter, and the filtrate collected for assay in a new receptacle (e.g., in a luminometer) following addition of a substrate for the indicator enzyme (e.g., luciferase substrate). Alternatively, the indicator signal may be measured directly on the filter.

[0135] In various embodiments, the purified parental indicator phage does not comprise the detectable indicator itself, because the parental phage can be purified before it is used for incubation with a test sample. Expression of late (Class III) genes occurs late in the viral life cycle. In some embodiments of the present invention, parental phage may be purified to exclude any existing indicator protein (e.g., luciferase). In some embodiments, expression of the indicator gene during bacteriophage replication following infection of host bacteria results in a soluble indicator protein product. Thus, in many embodiments, it is not necessary to separate parental from progeny phage prior to the detecting step. In an embodiment, the microorganism is a bacterium and the indicator phage is a bacteriophage. In an embodiment, the indicator moiety is soluble luciferase, which is released upon lysis of the host microorganism.

[0136] Thus, in an alternate embodiment, the indicator substrate (e.g., luciferase substrate) may be incubated with the portion of the sample that remains on a filter or bound to a plate surface. Accordingly, in some embodiments the solid support is a 96-well filter plate (or regular 96-well plate), and the substrate reaction may be detected by placing the plate directly in the luminometer.

[0137] For example, in an embodiment, the invention may comprise a method for detecting Listeria spp. comprising the steps of infecting cells captured on a 96-well filter plate with a plurality of parental indicator phage capable of expressing luciferase upon infection; washing excess phage away; adding BHI broth and allowing time for phage to replicate and lyse the specific Listeria spp. target (e.g., 60-240 minutes); and detecting the indicator luciferase by adding luciferase substrate and measuring luciferase activity directly in the 96-well plate, wherein detection of luciferase activity indicates that the Listeria spp. is present in the sample.

[0138] In another embodiment, the invention may comprise a method for detecting Listeria spp. comprising the steps of infecting cells in liquid solution or suspension in a 96-well plate with a plurality of parental indicator phage capable of expressing luciferase upon infection; allowing time for phage to replicate and lyse the specific Listeria spp. target (e.g., 60-240 minutes); and detecting the indicator luciferase by adding luciferase substrate and measuring luciferase activity directly in the 96-well plate, wherein detection of luciferase activity indicates that the Listeria spp. is present in the sample. In such an embodiment no capturing step is necessary. In some embodiments, the liquid solution or suspension may be a consumable test sample, such as a vegetable wash. In some embodiments, the liquid solution or suspension may be a vegetable wash fortified with concentrated Luria-Bertani (LB) Broth, Buffered Peptone Water (BPW) or Tryptic Soy Broth or Tryptone Soy Broth (TSB), Brain Heart Infusion (BHI) Buffered Listeria Enrichment Broth (BLEB) University of Vermont (UVM) Broth, or Fraser Broth. In some embodiments, the liquid solution or suspension may be bacteria diluted in BHI Broth.

[0139] In some embodiments, lysis of the bacterium may occur before, during, or after the detection step. Experiments suggest that infected unlysed cells may be detectable upon addition of luciferase substrate in some embodiments. Presumably, luciferase may exit cells and/or luciferase substrate may enter cells without complete cell lysis. Thus, for embodiments utilizing the spin filter system, where only luciferase released into the lysate (and not luciferase still inside intact bacteria) is analyzed in the luminometer, lysis is required for detection. However, for embodiments utilizing filter plates or 96-well plates with sample in solution or suspension, where the original plate full of intact and lysed cells is directly assayed in the luminometer, lysis is not necessary for detection.

[0140] In some embodiments, the reaction of indicator moiety (e.g., luciferase) with substrate may continue for 60 minutes or more, and detection at various time points may be desirable for optimizing sensitivity. For example, in embodiments using 96-well filter plates as the solid support and luciferase as the indicator, luminometer readings may be taken initially and at 10- or 15-minute intervals until the reaction is completed.

[0141] Surprisingly, high concentrations of phage utilized for infecting test samples have successfully achieved detection of very low numbers of a target microorganism in a very short timeframe. The incubation of phage with a test sample in some embodiments need only be long enough for a single phage life cycle. In some embodiments, the bacteriophage concentration for this incubating step is greater than 7 x 10 ⁶ , 8 x 10 ⁶ , 9 x 10 ⁶ , 1.0 x 10 ⁷ , 1.1 x 10 ⁷ , 1.2 x 10 ⁷ , 1.3 x 10 ⁷ , 1.4 x 10 ⁷ , 1.5 x 10 ⁷ , 1.6 x 10 ⁷ , 1.7 x 10 ⁷ , 1.8 x 10 ⁷ , 1.9 x 10 ⁷ , 2.0 x 10 ⁷ , 3.0 x 10 ⁷ , 4.0 x 10 ⁷ , 5.0 x 10 ⁷ , 6.0 x 10 ⁷ , 7.0 x 10 ⁷ , 8.0 x 10 ⁷ , 9.0 x 10 ⁷ , or 1.0 x 10 ⁸ PFU/mL. [0142] Success with such high concentrations of phage is surprising because the large numbers of phage were previously associated with “lysis from without,” which killed target cells and thereby prevented generation of useful signal from earlier phage assays. It is possible that the clean-up of prepared phage stocks described herein helps to alleviate this problem (e.g., clean-up by cesium chloride isopycnic density gradient ultracentrifugation), because in addition to removing any contaminating luciferase associated with the phage, this clean-up may also remove ghost particles (particles that have lost DNA). The ghost particles can lyse bacterial cells via “lysis from without,” killing the cells prematurely and thereby preventing generation of indicator signal. Electron microscopy demonstrates that a crude phage lysate (i.e., before cesium chloride clean-up) may have greater than 50% ghosts. These ghost particles may contribute to premature death of the microorganism through the action of many phage particles puncturing the cell membrane. Thus ghost particles may have contributed to previous problems where high PFU concentrations were reported to be detrimental. Moreover, a very clean phage prep allows the assay to be performed with no wash steps, which makes the assay possible to perform without an initial concentration step. Some embodiments do include an initial concentration step, and in some embodiments this concentration step allows a shorter enrichment incubation time.

[0143] Some embodiments of testing methods may further include confirmatory assays. A variety of assays are known in the art for confirming an initial result, usually at a later point in time. For example, the samples can be cultured (e.g., selective chromogenic plating), and PCR can be utilized to confirm the presence of the microbial DNA, or other confirmatory assays can be used to confirm the initial result.

[0144] In certain embodiments, the methods of the present invention combine the use of a binding agent (e.g., antibody) to purify and/or concentrate a microorganism of interest such as Listeria spp. from the sample in addition to detection with an infectious agent. For example, in certain embodiments, the present invention comprises a method for detecting a microorganism of interest in a sample comprising the steps of: capturing the microorganism from the sample on a prior support using a capture antibody specific to the microorganism of interest such as Listeria spp.,' incubating the sample with a recombinant bacteriophage that infects Listeria spp. wherein the recombinant bacteriophage comprises an indicator gene inserted into a late gene region of the bacteriophage such that expression of the indicator gene during bacteriophage replication following infection of host bacteria results in a soluble indicator protein product; and detecting the indicator protein product, wherein positive detection of the indicator protein product indicates that Listeria spp. is present in the sample.

[0145] In some embodiments synthetic phage are designed to optimize desirable traits for use in pathogen detection assays. In some embodiments bioinformatics and previous analyses of genetic modifications are employed to optimize desirable traits. For example, in some embodiments, the genes encoding phage tail proteins can be optimized to recognize and bind to particular species of bacteria. In other embodiments the genes encoding phage tail proteins can be optimized to recognize and bind to an entire genus of bacteria, or a particular group of species within a genus. In this way, the phage can be optimized to detect broader or narrower groups of pathogens. In some embodiments, the synthetic phage may be designed to improve expression of the reporter gene. Additionally and/or alternatively, in some instances, the synthetic phage may be designed to increase the burst size of the phage to improve detection.

[0146] In some embodiments, the stability of the phage may be optimized to improve shelflife. For example, enzybiotic solubility may be increased in order to increase subsequent phage stability. Additionally and/or alternatively phage thermostability may be optimized.

Thermostable phage better preserve functional activity during storage thereby increasing shelflife. Thus, in some embodiments, the thermostability and/or pH tolerance may be optimized.

[0147] In some embodiments the genetically modified phage or the synthetically derived phage comprises a detectable indicator. In some embodiments the indicator is a luciferase. In some embodiments the phage genome comprises an indicator gene (e.g., a luciferase gene or another gene encoding a detectable indicator).

Systems and Kits of the Invention

[0148] In some embodiments, the invention comprises systems (e.g., automated systems or kits) comprising components for performing the methods disclosed herein. In some embodiments, indicator phage are comprised in systems or kits according to the invention. Methods described herein may also utilize such indicator phage systems or kits. Some embodiments described herein are particularly suitable for automation and/or kits, given the minimal amount of reagents and materials required to perform the methods. In certain embodiments, each of the components of a kit may comprise a self-contained unit that is deliverable from a first site to a second site.

[0149] In some embodiments, the invention comprises systems or kits for rapid detection of a microorganism of interest in a sample. The systems or kits may in certain embodiments comprise a component for incubating the sample with an infectious agent specific for the microorganism of interest, wherein the infectious agent comprises an indicator moiety and a component for detecting the indicator moiety. In some embodiments of both the systems and the kits of the invention, the infectious agent is a recombinant bacteriophage that infects the bacterium of interest, and the recombinant bacteriophage comprises an indicator gene inserted into a late gene region of the bacteriophage as the indicator moiety such that expression of the indicator gene during bacteriophage replication following infection of host bacteria results in a soluble indicator protein product. Some systems further comprise a component for capturing the microorganism of interest on a solid support.

[0150] In other embodiments, the invention comprises a method, system, or kit for rapid detection of a microorganism of interest in a sample, comprising an infectious agent component that is specific for the microorganism of interest, wherein the infectious agent comprises an indicator moiety, and a component for detecting the indicator moiety. In some embodiments, the bacteriophage is a Tequatravirus, Vil, Kuttervirus, Homburgvirus, Pecentumvirus, o Listeria 5/?/?. -specific bacteriophage. In one embodiment, the recombinant bacteriophage is derived from Listeria 5/?/?. -specific bacteriophage. In certain embodiments, the recombinant bacteriophage is highly specific for a particular bacterium. For example, in certain embodiments, the recombinant bacteriophage is highly specific for Listeria spp. In an embodiment, the recombinant bacteriophage can distinguish Listeria spp. in the presence of other types of bacteria. In certain embodiments, a system or kit detects as few as 1, 10, 15, 20, 30, 40, 50, 60, 70, 80, 90, or 100 specific bacteria in the sample.

[0151] In certain embodiments, the systems and/or kits may further comprise a component for washing the captured microorganism sample. Additionally or alternatively, the systems and/or kits may further comprise a component for determining amount of the indicator moiety, wherein the amount of indicator moiety detected corresponds to the amount of microorganism in the sample. For example, in certain embodiments, the system or kit may comprise a luminometer or other device for measuring a luciferase enzyme activity.

[0152] In some systems and/or kits, the same component may be used for multiple steps. In some systems and/or kits, the steps are automated or controlled by the user via computer input and/or wherein a liquid-handling robot performs at least one step.

[0153] Thus in certain embodiments, the invention may comprise a system or kit for rapid detection of a microorganism of interest in a sample, comprising: a component for incubating the sample with an infectious agent specific for the microorganism of interest, wherein the infectious agent comprises an indicator moiety; a component for capturing the microorganism from the sample on a solid support; a component for washing the captured microorganism sample to remove unbound infectious agent; and a component for detecting the indicator moiety. In some embodiments, the same component may be used for steps of capturing and/or incubating and/or washing (e.g., a filter component). Some embodiments additionally comprise a component for determining the amount of the microorganism of interest in the sample, wherein the amount of indicator moiety detected corresponds to the amount of microorganism in the sample. Such systems can include various embodiments and subembodiments analogous to those described above for methods of rapid detection of microorganisms. In an embodiment, the microorganism is a bacterium and the infectious agent is a bacteriophage. In a computerized system, the system may be fully automated, semi-automated, or directed by the user through a computer (or some combination thereof).

[0154] In some embodiments, the system may comprise a component for isolating the microorganism of interest from the other components in the sample.

[0155] In an embodiment, the invention comprises a system or kit comprising components for detecting a microorganism of interest comprising: a component for isolating at least one microorganism from other components in the sample; a component for infecting at least one microorganism with a plurality of a parental infectious agent; a component for lysing at least one infected microorganism to release progeny infectious agents present in the microorganism; and a component for detecting the progeny infectious agents, or with greater sensitivity, a soluble protein encoded and expressed by the infectious agent, wherein detection of the infectious agent or a soluble protein product of the infectious agent indicates that the microorganism is present in the sample. The infectious agent may comprise Listeria-specific NANOLUC® bacteriophage carrying the NANOLUC® indicator gene.

[0156] The systems or kits may comprise a variety of components for detection of progeny infectious agents. For example, in an embodiment, the progeny infectious agent (e.g., bacteriophage) may comprise an indicator moiety. In an embodiment, the indicator moiety in the progeny infectious agent (e.g., bacteriophage) may be a detectable moiety that is expressed during replication, such as a soluble luciferase protein.

[0157] In other embodiments, the invention may comprise a kit for rapid detection of a microorganism of interest in a sample, the system comprising: a component for incubating the sample with an infectious agent specific for the microorganism of interest, wherein the infectious agent comprises an indicator moiety; a component for capturing the microorganism from the sample on a solid support; a component for washing the captured microorganism sample to remove unbound infectious agent; and a component for detecting the indicator moiety. In some embodiments, the same component may be used for steps of capturing and/or incubating and/or washing. Some embodiments additionally comprise a component for determining amount of the microorganism of interest in the sample, wherein the amount of indicator moiety detected corresponds to the amount of microorganism in the sample. Such kits can include various embodiments and subembodiments analogous to those described above for methods of rapid detection of microorganisms. In an embodiment, the microorganism is a bacterium and the infectious agent is a bacteriophage.

[0158] In some embodiments, the kit or system comprises (1) Listeria recombinant phage cocktail, (2) lysis buffer, (3) assay buffer, (4) luciferase substrate, (5) 96 well plate, (6) plate sealing tape, and (7) package instructions. In some embodiments the kit or system comprises two or more of the components enumerated above, or substantially similar alternatives (e.g., 384-well plate or any other configuration/container).

[0159] In some embodiments, a kit may comprise a component for isolating the microorganism of interest from the other components in the sample.

[0160] These systems and kits of the invention include various components. As used herein, the term “component” is broadly defined and includes any suitable apparatus or collections of apparatuses suitable for carrying out the recited method. The components need not be integrally connected or situated with respect to each other in any particular way. The invention includes any suitable arrangements of the components with respect to each other. For example, the components need not be in the same room. But in some embodiments, the components are connected to each other in an integral unit. In some embodiments, the same components may perform multiple functions.

Computer Systems and Computer Readable Media

[0161] The system, as described in the present technique or any of its components, may be embodied in the form of a computer system. Typical examples of a computer system include a general-purpose computer, a programmed microprocessor, a microcontroller, a peripheral integrated circuit element, and other devices or arrangements of devices that are capable of implementing the steps that constitute the method of the present technique.

[0162] A computer system may comprise a computer, an input device, a display unit, and/or the Internet. The computer may further comprise a microprocessor. The microprocessor may be connected to a communication bus. The computer may also include a memory. The memory may include random access memory (RAM) and read only memory (ROM). The computer system may further comprise a storage device. The storage device can be a hard disk drive or a removable storage drive such as a floppy disk drive, optical disk drive, etc. The storage device can also be other similar means for loading computer programs or other instructions into the computer system. The computer system may also include a communication unit. The communication unit allows the computer to connect to other databases and the Internet through an I/O interface. The communication unit allows the transfer to, as well as reception of data from, other databases. The communication unit may include a modem, an Ethernet card, or any similar device which enables the computer system to connect to databases and networks such as LAN, MAN, WAN and the Internet. The computer system thus may facilitate inputs from a user through input device, accessible to the system through I/O interface.

[0163] A computing device typically will include an operating system that provides executable program instructions for the general administration and operation of that computing device, and typically will include a computer-readable storage medium (e.g., a hard disk, random access memory, read only memory, etc.) storing instructions that, when executed by a processor of the server, allow the computing device to perform its intended functions. Suitable implementations for the operating system and general functionality of the computing device are known or commercially available, and are readily implemented by persons having ordinary skill in the art, particularly in light of the disclosure herein.

[0164] The computer system executes a set of instructions that are stored in one or more storage elements, in order to process input data. The storage elements may also hold data or other information as desired. The storage element may be in the form of an information source or a physical memory element present in the processing machine.

[0165] The environment can include a variety of data stores and other memory and storage media as discussed above. These can reside in a variety of locations, such as on a storage medium local to (and/or resident in) one or more of the computers or remote from any or all of the computers across the network. In a particular set of embodiments, the information may reside in a storage-area network (“SAN”) familiar to those skilled in the art. Similarly, any necessary files for performing the functions attributed to the computers, servers, or other network devices may be stored locally and/or remotely, as appropriate. Where a system includes computing devices, each such device can include hardware elements that may be electrically coupled via a bus, the elements including, for example, at least one central processing unit (CPU), at least one input device (e.g., a mouse, keyboard, controller, touch screen, or keypad), and at least one output device (e.g., a display device, printer, or speaker). Such a system may also include one or more storage devices, such as disk drives, optical storage devices, and solid-state storage devices such as random access memory ("RAM") or read-only memory ("ROM"), as well as removable media devices, memory cards, flash cards, etc.

[0166] Such devices also can include a computer-readable storage media reader, a communications device (e.g., a modem, a network card (wireless or wired), an infrared communication device, etc.), and working memory as described above. The computer-readable storage media reader can be connected with, or configured to receive, a computer-readable storage medium, representing remote, local, fixed, and/or removable storage devices as well as storage media for temporarily and/or more permanently containing, storing, transmitting, and retrieving computer-readable information. The system and various devices also typically will include a number of software applications, modules, services, or other elements located within at least one working memory device, including an operating system and application programs, such as a client application or Web browser. It should be appreciated that alternate embodiments may have numerous variations from that described above. For example, customized hardware might also be used and/or particular elements might be implemented in hardware, software (including portable software, such as applets), or both. Further, connection to other computing devices such as network input/output devices may be employed.

[0167] Non-transient storage media and computer readable media for containing code, or portions of code, can include any appropriate media known or used in the art, including storage media and communication media, such as but not limited to volatile and non-volatile, removable and non-removable media implemented in any method or technology for storage and/or transmission of information such as computer readable instructions, data structures, program modules, or other data, including RAM, ROM, EEPROM, flash memory or other memory technology, CD-ROM, digital versatile disk (DVD) or other optical storage, magnetic cassettes, magnetic tape, magnetic disk storage or other magnetic storage devices, or any other medium which can be used to store the desired information and which can be accessed by the a system device. Based on the disclosure and teachings provided herein, a person of ordinary skill in the art will appreciate other ways and/or methods to implement the various embodiments.

[0168] A computer-readable medium may comprise, but is not limited to, an electronic, optical, magnetic, or other storage device capable of providing a processor with computer- readable instructions. Other examples include, but are not limited to, a floppy disk, CD-ROM, DVD, magnetic disk, memory chip, ROM, RAM, SRAM, DRAM, content-addressable memory ("CAM"), DDR, flash memory such as NAND flash or NOR flash, an ASIC, a configured processor, optical storage, magnetic tape or other magnetic storage, or any other medium from which a computer processor can read instructions. In one embodiment, the computing device may comprise a single type of computer-readable medium such as random access memory (RAM). In other embodiments, the computing device may comprise two or more types of computer-readable medium such as random access memory (RAM), a disk drive, and cache. The computing device may be in communication with one or more external computer-readable mediums such as an external hard disk drive or an external DVD or Blu-Ray drive.

[0169] As discussed above, the embodiment comprises a processor which is configured to execute computer-executable program instructions and/or to access information stored in memory. The instructions may comprise processor-specific instructions generated by a compiler and/or an interpreter from code written in any suitable computer-programming language including, for example, C, C++, C#, Visual Basic, Java, Python, Perl, JavaScript, and ActionScript (Adobe Systems, Mountain View, Calif.). In an embodiment, the computing device comprises a single processor. In other embodiments, the device comprises two or more processors. Such processors may comprise a microprocessor, a digital signal processor (DSP), an application-specific integrated circuit (ASIC), field programmable gate arrays (FPGAs), and state machines. Such processors may further comprise programmable electronic devices such as PLCs, programmable interrupt controllers (PICs), programmable logic devices (PLDs), programmable read-only memories (PROMs), electronically programmable read-only memories (EPROMs or EEPROMs), or other similar devices.

[0170] The computing device comprises a network interface. In some embodiments, the network interface is configured for communicating via wired or wireless communication links. For example, the network interface may allow for communication over networks via Ethernet, IEEE 802.11 (Wi-Fi), 802.16 (Wi-Max), Bluetooth, infrared, etc. As another example, network interface may allow for communication over networks such as CDMA, GSM, UMTS, or other cellular communication networks. In some embodiments, the network interface may allow for point-to-point connections with another device, such as via the Universal Serial Bus (USB), 1394 FireWire, serial or parallel connections, or similar interfaces. Some embodiments of suitable computing devices may comprise two or more network interfaces for communication over one or more networks. In some embodiments, the computing device may include a data store in addition to or in place of a network interface.

[0171] Some embodiments of suitable computing devices may comprise or be in communication with a number of external or internal devices such as a mouse, a CD-ROM, DVD, a keyboard, a display, audio speakers, one or more microphones, or any other input or output devices. For example, the computing device may be in communication with various user interface devices and a display. The display may use any suitable technology including, but not limited to, LCD, LED, CRT, and the like.

[0172] The set of instructions for execution by the computer system may include various commands that instruct the processing machine to perform specific tasks such as the steps that constitute the method of the present technique. The set of instructions may be in the form of a software program. Further, the software may be in the form of a collection of separate programs, a program module with a larger program or a portion of a program module, as in the present technique. The software may also include modular programming in the form of object-oriented programming. The processing of input data by the processing machine may be in response to user commands, results of previous processing, or a request made by another processing machine.

[0173] While the present invention has been disclosed with references to certain embodiments, numerous modifications, alterations and changes to the described embodiments are possible without departing from the scope and spirit of the present invention, as defined in the appended claims. Accordingly, it is intended that the present invention not be limited to the described embodiments, but that it have the full scope defined by the language of the following claims, and equivalents thereof.

EXAMPLES

[0174] Results depicted in the following examples demonstrate detection of a low number of cells, as few as 1 Listeria bacteria, in a shortened time to results.

Example 1. Creation and Isolation of Indicator Phage from Listeria-Specific Bacteriophage

[0175] Indicator Phage Listeria-specific LMA4.NANOLUC, LMA8.NANOLUC, and other Listeria bacteriophages were created through homologous recombination using procedures as previously described. See Figures 1-3 which depict and describe recombinant Listeria phages derived from LMA4 and LMA8.

[0176] The genomic sequences of these phage were obtained through whole genome sequencing using the Illumina MiSeq system with de novo sequence assembly. Based on previously known and annotated genomes of related phage, the late gene regions and Major Capsid Protein genes were located on the new phage genomes. Plasmids were designed and synthesized to insert NANOLUC® along with the appropriate late gene promoter and ribosomal binding site, flanked by approximately 200-500 bp of matching phage sequence to promote homologous recombination. [0177] Target bacteria were transformed with the Homologous Recombination Plasmids under appropriate antibiotic selection and infected with their respective wild-type phage to allow for homologous recombination with the plasmid. Following homologous recombination to generate the recombinant bacteriophage genomes, a series of titer and enrichment steps was used to isolate specific recombinant bacteriophages that express NANOLUC® as previously described.

[0178] Finally, large-scale production was performed to obtain high titer stocks appropriate for use in the Listeria spp. detection assays. Cesium chloride isopycnic density gradient centrifugation may be used to separate phage particles from contaminating luciferase protein to reduce background. In other embodiments, sucrose isopycnic density gradient centrifugation may be used to separate phage particles from contaminating luciferase protein to reduce background.

Example 2. Inoculated Sponge Sample — Sponge Assay for Listeria

[0179] EZ Reach polyurethabe sponge samplers were pre-wetted with Dey/Engley Broth and spiked with < 1 CFU of Listeria monocytogenes, which was diluted from an overnight culture or with 100 CFU challenge bacteria (Cronobacter sakazakii).

[0180] The handle of the sponge was broken off and the sponge was placed into medium in a bag. Buffered Listeria Enrichment Broth (BLEB) (Remel) medium (10 or 90 mL) was added to cover as much of the sponge as possible. The sponge was then gently massaged to release bacteria into the medium and enrichment followed at 35 °C for 16-18 hours or 24 hours. After enrichment, sponges were gently massaged/squeezed to remove the liquid and were then moved away from the medium in the bag. The bag was then gently massaged to mix the contents. 150 pl aliquots were transferred to a 96-well plate. The sponge was then placed into the medium for further enrichment at 35 °C, if necessary.

[0181] Sponge samples were tested with Listeria phage cocktail following 1-hour and 4-hour infection. Briefly, phage reagent (10 pl) was added to samples and the samples incubated at 30 °C for 1 hour or 4 hours. Finally, 65 pl of Luciferase Master Mix reagent was added to each well and gently mixed by pipetting up and down. Samples were read (i.e., luminescence detected) on a luminometer (GloMax96) instrument 3 minutes after substrate addition. Sponges/swabs were placed back into the bag/tube and enrichment continued at 35 °C for a total of 24 hours. Optionally, aliquots may be taken and further enriched and tested again.

[0182] Results are shown in Figure 5. A signal to background ratio (S/B) greater than 3 was considered positive. The background level was determined to be 100 RLU based on prior phage characterizations. These experiments indicate that the Listeria Phage Assay can detect a 1 CFU spike of L. monocytogenes ATCC 19115 following 16-18 hours of enrichment and 1 hour of infection. Figure 5A (10 mL medium) shows that sponge samples 1 and 4 were negative for detection of Listeria (i.e., S/B < 3.0). Sponge samples 2, 3, 5, and the 10 CFU control were all positive for all enrichment and infection times. Figure 5B (90 mL medium) shows that sponge 1 was negative for detection of Listeria while all other samples had positive detection. These data indicate that sponges with 10 mL of added medium generated a better signal with higher relative S/B than samples with 90 mL added medium.

[0183] Thus the experiment demonstrates it is possible to detect 1 CFU spike from an overnight culture with all the conditions tried (i.e., 16-18 hr enrichment - 1 hr infection, 16-18 hr enrichment - 4 hr infection, 24 hr enrichment -1 hr infection, and 24 hr enrichment - 4 hr infection.

Example 3. Environmental Surface Sample — Sponge Assay for Listeria

[0184] Stainless steel surfaces were inoculated with the indicated number of cells in medium. Cells were allowed dry onto the surface and kept at room temperature for 18-24 hours before being swabbed with EZ Reach polyurethane sponge samplers were pre wet with Letheen medium (World BioProducts). Listeria monocytogenes 19115 was used as the target and Staphylococcus aureus 12600 was used as the challenge strain.

[0185] The handle of the sponge was broken off and the sponge was placed back into medium in the bag. Buffered Listeria Enrichment Broth (BLEB) (Remel) medium (20 mL) was added to cover as much of the sponge in medium as possible. The sponge was gently massaged to release bacteria into the medium and enrichment followed at 35 °C for 20 hours. After enrichment, sponges were gently massaged, squeezed to remove the liquid, and then moved away from the medium in the bag. The bag was gently massaged to mix the contents. 150 pl aliquots were transferred to a 96-well plate. The sponge was replaced into the medium and incubated at 35 °C if further enrichment was necessary. [0186] Sponge samples were tested with Listeria phage cocktail following 1-hour and 4-hour infection. Briefly, phage reagent (10 pl) was added to samples and incubated at 30 °C for 4 hours. Finally, 65 pl of Luciferase Master Mix reagent was added to each well and gently mixed by pipetting up and down. Samples were read (i.e., luminescence detected) on a GloMax96 instrument 3 minutes after substrate addition.

[0187] Phage reagent (10 pl) was added to samples and incubated at 30 °C for 4 hours. Finally 65 pl of Luciferase Master Mix reagent was added to each well and gently mixed by pipetting up and down. Samples were read (i.e., luminescence detected) on a GloMax96 instrument 3 minutes (180 seconds) after substrate addition.

[0188] Figure 6 shows the RLU generated from the stainless steel surface swabs. Samples generating RLU >300 were considered positive. These data show that the Listeria Phage Assay can detect a 100 CFU surface inoculation of L. monocytogenes with a 20-hour enrichment and 4 hours of infection in the presence of a non-Listeria bacteria present at a 10-fold greater CFU level than the target Listeria bacteria. Sample 2 and the negative control were negative for detection of L. monocytogenes. All other samples, including the positive control, were positive. Compared to the spiked sponge experiments, the swabs of stainless steel required longer enrichment period and a higher CFU level for positive detection. This can be attributed to several variables, including increased injury to surface inoculated cells as compared to those from an overnight culture. Surface inoculated cells typically have significant loss of viability. Also, recovery of cells form a surface with sponges can be highly variable.

Example 4. Bacteriophage Isolation, Purification, and High Titer Stock Preparation

[0189] The Listeria grayi bacteriophage LPJP1 was isolated from silage collected from a Wisconsin farm. 3 g of silage was added to 30 mL of BHI media and allowed to diffuse at 2-8 °C for 72 h. To remove bacteria and debris, this solution was centrifuged at 4700 x g for 10 min and the supernatant passed through a 0.45 pm filter followed by a 0.2 pm filter (Nalgene, Rochester, NY, USA). As an initial assessment to determine phage presence, a spot test was performed using a standard overlay method (Gratia, A., Ann. Inst. Pasteur 1936, 57, 652-676). Briefly, 100 pL of a log phase culture of the L. grayi strain (ATCC 19120) was mixed with 3 mL of melted 0.5% (w/v) semi-solid BHI agar and then poured evenly atop BHI agar plates to form a lawn. Once the semi-solid agar solidified, plates were spotted with 5 pL of the filtered supernatant and incubated overnight at 30 °C. As spot testing yielded promising results, isolation of single plaques was pursued using a modification of the above overlay method. 100 μL of a log phase culture, 100 pL of diluted filtered supernatant, and 3 mL of melted semi-solid was poured atop a BHI agar plate and incubated overnight at 30 °C. Individual plaques were then isolated by picking them with a pipette tip and resuspending them in 1 mL BHI media. This process of single plaque isolation, dilution, and plating was serially repeated five times to ensure a pure culture of a single phage.

[0190] High titer phage stocks were generated from broth lysates as described previously (Nguyen, et al.. Sci Rep 2020, 10, 17463). Briefly, a log phase culture of L. grayi (ATCC 19120) was infected at a multiplicity of infection (MOI) of 0.05 and incubated statically for 5 min to facilitate bacteriophage adsorption. Infected cells were diluted into fresh BHI media and incubated at 30 °C with shaking at 225 rpm until lysis was visually apparent. To remove debris, the lysate was clarified by centrifugation. The supernatant was centrifuged to pellet phage and this pellet was resuspended in TMS Buffer (50 mM Tris-HCl pH 7.8, 10 mM MgC12, and 300 mM NaCl). Resuspended phage were treated with RNase and DNase I before being further purified using a sucrose density gradient (10-30%) and ultimately being resuspended in SM buffer (50 mM Tris-HCl pH 7.5, 8 mM MgSO4 7H2O, 100 mM NaCl, and 0.01% (w/v) gelatin). This method frequently yielded stock solutions with a titer around 1.5 x 1011 plaque forming units (pfu) per mL.

[0191] LPJP1 formed small clear plaques at 30 °C on the L. grayi strain ATCC 19120 (Figure 9). Interestingly, plaques were not observed at 37 °C. The mechanism behind this phenotype is not fully understood but is consistent with temperature-dependent plaque formation observed with other Listeria phages. A one-step growth curve on LPJP1 revealed a burst size of approximately 50 to 60 pfu with cycle time of roughly 60 min. To our knowledge, LPJP1 is the first published phage capable of lysing and forming plaques on /.. grayi.

[0192] Transmission electron microscopy was used to confirm phage presence and determine the morphology of LPJP1. Microscopy revealed the presence of a large icosahedral head, nonflexible long straight tail, and contractile outer tail sheath (Figure 7A,B). These characteristics match the morphology of the Myoviridae family of dsDNA phage (Fokine and Rossmann, Bacteriophage 2014). Example 5. Bacteriophage Characterization (Burst size, Replication Cycle Time, and Microscopy)

[0193] To calculate the burst size and replication cycle time of LPJP1, a standard one-step growth curve was performed using the L. grayi strain ATCC 19120, as described previously (Ellis and Delbriick, Journal of General Physiology 1939, 22, 365-384).

[0194] Transmission electron microscopy (TEM) of LPJP1 was performed as described previously (Nguyen, et al., Sci Rep 2020, 70, 17463). Briefly, 400 mesh grids coated with a thin carbon film were glow discharged, floated on purified high titer phage stock, and subsequently stained with 2% uranyl acetate. A Technai G2 Spirit BioTWIN with an accelerating voltage set at 30 kV was used for image capture.

Example 6. Bacteriophage DNA Isolation, Sequencing, and PCR

[0195] To isolate phage DNA, 6* 10 ¹⁰ pfu/mL were first heated at 95 °C for 2 min and then allowed to cool to room temperature. Sodium dodecyl sulfate (SDS), ethylenediaminetetracetic acid (EDTA), and proteinase K were added to a final concentration of 0.1% SDS, 5 mM EDTA, and 53 pg/mL proteinase K. This mixture was incubated for 1 h at 50 °C before performing three rounds of phenol/chloroform extractions, serially separating the aqueous phase. After the addition of 0.1 volumes of 3 M sodium acetate and 2.5 volumes of ethanol to this phase, DNA was precipitated at -80 °C. Precipitated DNA was pelleted and washed twice with 70% ethanol. Washed DNA was pelleted once again, air dried, and finally resuspended in 10 mM Tris-HCL pH 8.0.

[0196] Phage DNA was quantified using absorbance at 260 nm on a NanoDrop (Thermo Fisher Scientific, Waltham, MA, USA) and sent to Laragen Inc. (Los Angeles, CA, USA) for sequencing. Laragen Inc. quantified dsDNA using a Qubit dsDNA HS assay kit (Thermo Fisher Scientific, Waltham, MA, USA) and performed library preparation using the Nextera DNA Flex library prep (Illumina, San Diego, CA, USA). When successful library preparation was achieved, samples underwent MiSeq whole genome sequencing (Illumina, San Diego, CA, USA) and contig assembly. When indicated, DNA was amplified prior to sequencing using a Illustra TempliPhi DNA amplification kit (Cytiva, Marlborough, MA, USA) according to manufacturer’s instructions. Amplified DNA was quantified and submitted for sequencing, as described above. Genome assemblies obtained from Laragen Inc. were examined for homology to other viruses using the Basic Local Alignment Search Tool (BLAST) (BLASTN, limited to viruses (taxid: 10239)) (Altschul, et al, Nucleic Acids Res 1997, 25, 3389-3402; Altschul, et al., J Mol Biol 1990, 275, 403-410).

[0197] Polymerase chain reaction (PCR) was performed using either the Q5 hot start high- fidelity DNA polymerase or the Q5U hot start high-fidelity DNA polymerase (New England BioLabs, Ipswich, MA, USA). DNA templates were either native phage DNA or TempliPhi- amplified DNA prepared as described above. To ensure elements of the TempliPhi reaction did not interfere with PCR, amplified DNA was cleaned up using a Monarch PCR and DNA cleanup kit (New England BioLabs, Ipswich, MA, USA). PCR was performed using 2 ng of DNA, either amplified or native, and either the Q5 or Q5U polymerase, as per manufacturer’s instructions. Primers were (5’- AGGAAACAGCTATGACATGATTACGTTATCATAAAACTTTCGATGTAC-3’) and (5’- ATT TATACTCTATTTAACGAGCGTATTGAGTTG-3’) and were obtained from Eurofins Genomics (Louisville, KY, USA). PCR reactions were assessed using gel electrophoresis. Half of each reaction was mixed with GelPilot DNA loading dye (Qiagen, Hilden, Germany) and loaded onto a 1% agarose gel (Bio-Rad Laboratories, Hercules, CA, USA) in standard Tris- acetate-EDTA (TAE) buffer. For size comparison, O’GeneRuler Ikb plus DNA ladder (Thermo Fisher Scientific, Waltham, MA, USA) was added to flanking wells. SYBR DNA Gel Strain (Invitrogen, Carlsbad, CA, USA) was included in the gel to allow visualization of results. The gel was electrophoresed for 100 Vh while submerged in TAE buffer. Gel imaging was performed using the Gel Doc EZ system and ImageLab (version 6.0.1) software (Bio-Rad, Hercules, CA, USA).

[0198] The success of library preparation only after DNA amplification with the phi29 bacteriophage polymerase could indicate the presence of modified base pairs, such as uracil, in the genome of LPJP1. This hypothesis was further supported with PCR. In particular, DNA isolated from LPJP1 could only be directly amplified when an uracil-tolerant polymerase, such as Q5U, was used (Figure 8). Importantly, modified base pairs are also found in several other jumbo phage, including those displaying limited homology to LPJP1. In particular, the genomes of the Bacillus jumbo phages AR9 and PBS1 and the Staphylococcus phage S6 were found to contain deoxyuridine in place of thymidine (Lavysh, et al., Virology 2016, 495, 185-196; Uchiyama, et al., ISME ./ 2014, 8, 1949-1952; Takahashi and Marmur, Nature 1963, 797, 794- 795). Furthermore, AR9 library preparation was performed following DNA amplification using the uracil-tolerant polymerase, KAPA HiFi Uracil+. The benefit of DNA amplification using an uracil-tolerant polymerase is clear. Thus, while it is possible that LPJP1 represents an exceptionally rare phage, it is equally likely that such jumbo phages have been overlooked due to technical limitations and challenges.

Example 7. Design and Engineering of Luciferase Reporter Phage Recombinants

[0199] Homologous recombination was used to insert a late gene promoter and NANOLUC® downstream of the predicted major capsid protein to create a NANOLUC®-expressing recombinant of LPJP1. No predicted genes are anticipated to be disrupted following recombination at this site. A predicted major capsid protein was identified in LPJP1 by manual screening of possible open reading frames in the LPJP1 genome assembly. This prediction was supported by homology observed using BLAST (BLASTP) (Altschul, et al., Nucleic Acids Res 1997, 25, 3389-3402; Altschul, et al., FEBS ./ 2005, 272, 5101-5109). A shuttle vector containing homology flanks to mediate recombination, a late gene promoter, and NANOLUC® sequence was designed as follows. The upstream flank begins with a Kpnl restriction site followed by 500 bp of homology upstream of the insertion site. The insertion site was immediately after the predicted major capsid protein of LPJP1. Following this flank, a promoter was added containing -10 and -35 elements from A51 l’s major capsid protein (a late gene) sequence and an A511 consensus ribosome binding site sequence (Loessner and Scherer, J Bacterial 1995, 777, 6601- 6609; Klumpp, et al., J Bacterial 2008, 190, 5753-5765). NANOLUC® coding sequence was added following this promoter. The downstream flank contained 500 bp of homology downstream of the target insertion site and was followed by a Sall restriction site. Sequences for both flanks and the promoter are provided (Table 1). The sequence of NANOLUC® has been previously described. These sequences were synthesized and inserted between the Kpnl and Sall restriction sites of the multiple cloning site in the previously described shuttle vector pCE104 (Murray, et al., 1. Infect Immun 1996, 64, 371-374).

Table 1. DNA Sequences Used in Homologous Recombination (HR)

Feature DNA Sequence GGTACCATGTACATCCAAATGGTGGATACAACATGCATCCGCATGAATGGCGCCGTGGTA TT CGTGACGTTATTGACTGGATGTCTCAAGCAATGAAAAATGATTACAAAACTTATGATGCT TA CTTTGTAATTGTTGGTAATCCAATTGACACTCAATTGATTCCTGACATTGAATGGGAATT CCA AGGAGCTACTGATGAAGTTGCGGGAATTAACGTTTCTTATAGCGTTGGTGCTTCTTCTAC AGT Upstream

, , TAACCGTTATAAAGTTGTTTCTTCTGACTTAGTACCTGCTGGAGATCTATTAATCTTTGC AGTT HR Flank ¹

CCTACTCGTGAAGACTTCAAAACTTACGAATACTACCCATACACTTTCAATATCGTT AATAAT TACAACAATGCTGTTAACCAAAGCGTTCCTAACATTATGCTTTCTCGCCGTTATACAGTT GAA GAATTTGTTCCAATTATCGGTAAAGTTACAATTAAAAACAACGATGCAACTCAATACGCT CG _ TTAA _ TAAATATTATGAACCTTTCAGAGACCTTTTGGTTTCTGAAAGGTTATTATTTATAAAAAT TTA AATTGGCGGTGCAACCATGCATATTGATTATGGTATTGAAAAGAATATATCAAAGTACTT AC ATGAAGAATTACTAACTGAAGATATCTATAATCATCCTTTATTAAAAAAGATTGATGATG AA TTTCAGAAAATATTAGATGAAGATAATATTAATGATACTAAACTACCAGTAACATCATAT AA Downstream

, , AAAAATTCAAAATATAATTAAATATGTCTCAACTATATTTAATATAAATTTAATTATAAC GAT HR Flank ²

TGATAACGATAATATCCTTACTTATGGAATGATGACATTTATTCCGGTTAAAAATCT AACAA AGATATCTAATAATATAAAGAAGATTGTACTTCAACCAAAAACTGGTTTTGAATATATTA AA ACTGAAGTTATTGAAATTAAAATACAGAAAAAATTAATATCTTTCATTAAGGATCCAAAC TT ACGTCGAC

Promoter ³ ATAGAGTATAAATTCTATTCAGTTTCGTATATTAATACTAGTAGATAGGAGGTGTTTCGA

¹ Upstream homologous recombination flank consists of a Kpnl restriction site (underlined) and 500 bp of homology immediately upstream of desired insertion site (predicted major capsid protein) ² Downstream homologous recombination flank consists of 500 bp of homology immediately downstream of desired insertion site, followed by a Sall restriction site (underlined) ³ Key elements of the promoter sequence used are underlined. -35 (ATAGAGTA) and -10 (TATATT) elements are from the late gene major capsid protein sequence of A511, while the ribosome binding site used (AGGAGGTG) is the reported A511 consensus sequence.

[0200] ATCC 19120, the L. grayi strain used during isolation of LPJP1, was also selected as a host for recombination. Electrocompetent ATCC 19120 was generated using a modification of a previously described method (Park, S.F.; Stewart, G.S. High-efficiency transformation of Listeria monocytogenes by electroporation of penicillin-treated cells. Gene 1990, 94, 129-132).

10 pg/mL of Penicillin G (Thermo Fisher Scientific, Waltham, MA, USA) was added to a log phase culture of ATCC 19120 and incubated for 1 h at 37 °C with shaking (225 rpm). Treated cultures were then chilled on ice for 30 min, pelleted, and washed three times with cold SMP (272 mM sucrose, ImM MgC12, 7mM Sodium phosphate pH 6.8). Cells were pelleted a final time and resuspended in ImL of cold SMP. 100 pL aliquots were frozen and stored at -80 °C until use. 100 ng of homologous recombination plasmid DNA was added to thawed electrocompetent cells, incubated on ice for 15 min, and transferred to a 0.2 cm cuvette. Electroporation was carried out using a MicroPulser electroporation apparatus (Bio-Rad Laboratories, Hercules, CA, USA) with voltage of 2.5 kV and a 2.8 msec time constant. Electroporated cells were recovered in fresh BHI for 2 h at 30 °C before being plated on BHI agar plates containing 5 pg/mL erythromycin sulfate (Alfa Aesar, Haverhill, MA, USA). Plates were incubated at 37 °C for 24 h before being examined for transformants.

[0201] Erythromycin-resistant colonies were picked, grown up BHI containing 5 pg/mL erythromycin sulfate, and infected with varying amounts of LPJP1 equivalent to MOIs of 0.01 to 0.1. Infections were incubated for 4.5 h at 30 °C with 225 rpm shaking. To remove debris and intact bacteria, samples were centrifuged for 2 min at 6,800 x g and the supernatant passed through a 0.45 pm filter. This solution was transferred to a 100 kDa pore protein concentrator PES column (Pierce Biotechnology, Rockford, IL) and buffer exchanged with TMS. Potential phage recombinants were identified from this reaction. Briefly, enrichment of limiting dilutions followed by screening for luciferase production was used to improve the likelihood of finding a recombination event. When found to be positive, these enrichments were plated to isolate single plaques on semi-solid agar, as described above. Candidate plaques were picked, mixed with diluted cultures of ATCC 19120, and evaluated for NANOLUC® production. Single plaque isolation, dilution, and plating was serially performed five times to establish a pure NANOLUC®-expressing recombinant, called LPJP1.NL. Using the same preparation method described above, high titer stocks of LPJP1.NL were made and sent for genome sequencing. Analysis of the assembled genome of LPJPl.NL verified that the homologous recombination occurred as desired, inserting the promoter and NANOLUC® downstream of the predicted major capsid protein.

Example 8. Limit of Detection of LPJP1.NL

[0202] The limit of detection of LPJPl.NL in L. grayi was determined as follows. A log phase culture (OD ₆₀₀ of 0.1 to 0.5) of the L. grayi strain ATCC 19120 was diluted in BHI media to achieve 10 to 100,000 CFU/mL. 100 pL of each bacterial dilution or BHI media was added to at least six replicate wells on a 96-well plate. Each well was infected with 10 pL of LPJP1.NL at 1.2 x io ⁷ pfu/mL and the infection was allowed to proceed for 4 h at 30 °C. At the end of the infection, 65 pL of a luciferase detection solution was added to each well. The luciferase detection solution consisted of 50 pL of NanoGio buffer, 15 pL of Renilla lysis buffer, and 1 pL of NanoGio substrate (Promega Corp., Madison, WI, USA). A GloMax Navigator luminometer (Promega Corp., Madison, WI, USA), set to a 3 min wait time and 1 sec integration, was used to detect light production. Using this method, relative light units (RLU) values were obtained for each well and averaged among replicates.

[0203] When indicated, the above protocol was modified to determine the effect of infection temperature in signal production. Bacteria were prepared and infected as described above with the following exception. For each burden, two wells were infected with LPJP1.NL. One set of wells was infected for 4 h at 30 °C, while the other set was infected for 4 h at 37 °C. RLU values were obtained using a luciferase detection solution as described above.

[0204] NANOLUC®-expressing bacteriophage typically yield robust signal following infection of even a few bacterial cells. In order to evaluate the sensitivity of LPJP1.NL for L. grayi, the limit of detection of this recombinant reporter was determined. LPJP1.NL was allowed to infect 0 to 10,000 CFU of L. grayi for 4 h at 30 °C. After addition of substrate, NANOLUC® production in each sample was quantified using a luminometer. Infection of L. grayi with LPJP1.NL yielded an easily detectable signal over media background and increased proportionally with CFU (Table 2). Background from media and reporter alone was a minimal 96 RLU while a single CFU of L. grayi was sufficient to achieve an average RLU signal of twice this amount. As expected, variation between replicate wells was noted when low bacterial burdens were tested. Overall, these results indicate that LPJP1.NL is a sensitive reporter capable of producing a signal over background from a single CFU of L. grayi after a 4 h infection.

Table 2. Limit of Detection of LPJP1NL in L. grayi

Detected Cells ¹ Replicate Wells Avg. RLU ² SD ³ % CV ⁴ S/B ⁵

0 6 96 6 6 1.0

1 10 191 135 71 2.0

2 10 553 327 59 5.8

5 10 1012 474 47 10.6

10 10 2565 1055 41 26.9

100 10 24,056 2463 10 251.9

1000 6 264,210 24,637 9 2766.6

10,000 6 4,414,026 322,722 7 46,220.2

¹ Log phase cultures of L. grayi (ATCC 19120) were diluted to the indicated burden and infected with LPJP1.NL for 4 h at 30 °C. ² Average (Avg.) Relative Light Units (RLU) across replicate wells. ³ Standard Deviation (SD) ⁴ Coefficient of Variation (CV) ⁵ Signal over background (S/B) was calculated by dividing the Avg. RLU for each condition by the Avg. RLU of background (0 cells). [0205] Previous concerns over the phenomenon of temperature-dependent plaque formation with Listeria phages and the implications on phage reporters have been raised (Tokman, J. I., et al., Front Microbiol 2016, 7, 631). Since LPJP1 shared this phenotype, an experiment was carried out to determine the role of temperature during infection on the signal production of LPJP1.NL. Minimal differences were noted between the RLU obtained from a 4 h infection at 30 °C or 37 °C and both temperatures yielded comparable results across all burdens (Table 3). In spite of the lack of plaque formation at 37 °C, the robust signal from LPJP1.NL at this temperature suggests that phage DNA was injected successfully. These results suggest that, while higher temperatures may prohibit plaque formation in many Listeria phage, increased temperatures do not impede the production of signal from Listeria phage reporters.

Table 3. Comparison of Limit of Detection After 30 °C or 37 °C Infection

Detected Cells i RLU - 30 °C ² RLU - 37 °C ²

0 89 (Neg.) 88 (Neg.)

1 248 (Pos.) 909 (Pos.)

2 821 (Pos.) 966 (Pos.)

5 1692 (Pos.) 2926 (Pos.)

10 2155 (Pos.) 2893 (Pos.)

100 24,407 (Pos.) 34,156 (Pos.)

1000 250,905 (Pos.) 391,186 (Pos.)

10,000 5,940,865 (Pos.) 5,546,562 (Pos.)

¹ Log phase cultures of L. grayi (ATCC 19120) were diluted to the indicated burden and infected with LPJP1.NL for 4 h at 30 °C or 37 °C. ² Relative Light Units (RLU) are provided. Positive (Pos.) and negative (Neg.) detection was determined for each sample using a threshold of 190 RLU, approximately twice media background.

Example 9. Genome Sequencing and Engineering of LPJP1

[0206] LPJP1 was sequenced in order to determine suitable siters for inserting a genetic construct. Initial attempts to sequence the genome of this phage were unsuccessful. Despite obtaining sufficient DNA quantity and quality, library preparation using bead-lined transposomes (Illumina, San Diego, CA, USA) could not be achieved, failing at DNA amplification. This library preparation method is generally considered to be quite robust, demonstrating resistance to poor DNA quality and productivity with various DNA quantities (Bruinsma, S. et al. BMC Genomics 2018, 19, 722). One possible explanation for this failure is the presence of modified DNA base pairs, which have been observed to serve a number of functions in some bacteriophage (Weigele, P. et al. Chem Rev 2016, 116, 12655-12687). In particular, the presence of deaminated base pairs, such as uracil or hypoxanthine, in DNA templates can inhibit commercial high-fidelity proof-reading archaeal polymerases (Fogg, MJ et al., Nat Struct Biol 2002, 9, 922-927; Russell, H.J. et al, Nucleic Acids Res 2009, 37, 7603-7611). DNA preparations of LPJP1 were amplified using the TempliPhi DNA amplification kit, which utilizes the Phi29 bacteriophage polymerase capable of reading past uracil-containing DNA (Reagin, M.J. et al., J Biomol Tech 2003, 14, 143-148; Serrano-Heras, G. et al. Proc Natl Acad Sci USA 2008, 105, 19044-19049). Library preparation was successfully completed using PCR- amplified DNA of LPJP1. Further support of both the presence of modified base pairs in LPJP1 and the ability to overcome this with the TempliPhi kit was obtained using the assembled sequence. Primers were designed to amplify an approximately 550 bp region within the LPJP1 genome. PCR amplification was performed using equivalent amounts of either native LPJP1 DNA or TempliPhi -treated LPJP1 DNA. The reaction was performed using either the Q5 polymerase or the uracil-tolerant Q5U polymerase. When these reactions were analyzed by gel electrophoresis, a distinct band of the expected size was observed with native DNA and the Q5U polymerase and TempliPhi -treated DNA with both polymerases (Figure 8). A clear difference was observed between the uracil-sensitive Q5 polymerase and the uracil-tolerant Q5U polymerase on native phage DNA. Importantly, the failure of the Q5 polymerase in PCR was specific to native DNA and TempliPhi-treated DNA could be effectively amplified by both polymerases. These results support the hypothesis that LPJP1 contains modified base pairs.

[0207] Assembly of LPJP1 sequences revealed a large genome, 223,580 bp in length. This crosses the threshold of 200,000 bp to be considered a jumbo phage (Hendrix, R.W. Curr Top Microbiol Immunol 2009, 328, 229-240). Two interesting sequence features were identified. First, LPJP1 had minimal homology to available viral nucleotide sequences when using BLAST . The top three matches by query coverage were phage vB BpuM-BpSP (8% query coverage, 67% identity), phage PBS1 (6% query coverage, 66% identity), and phage AR9 (6% query coverage, 66% identity). Of note, all three of these genomes are from jumbo phage infecting Bacillus (Yuan, Y. et al. Front Microbiol 2016, 7, 745; Lavysh, D. et al. Virology 2016, 495, 185-196). Secondly, LPJP1 has an abnormally low GC content (25.9%) when compared to its host /.. grayi (41.6%). Interestingly, this GC content discrepancy is also shared by the previously mentioned jumbo phage vB BpuM-BpSP (25.9%) compared to 41.2% for its B. pumilus host, and jumbo phage PBS1 (27.7%) and AR9 (27.8%) compared to 43.5% for their B. subtilis host. These basic features indicate that LPJP1 has homology, albeit limited, to jumbo phages capable of infecting another Gram-positive genus, Bacillus.

[0208] Manual examination of potential open reading frames in LPJP1 revealed a candidate major capsid protein. BLAST analysis of this protein sequence indicated homology with the precursor of major head subunit protein of the Bacillus jumbo phage AR9 as a top hit (97% query coverage, 40.5% identity). Amino acid homology was also observed with the structural protein sp46 precursor of both the jumbo phage Bacillus vB BpuM-BpSP (99% query coverage, 36.4% identity) and the Yersinia jumbo phage phiRl-37 (98% query coverage, 30.3% identity). Homologous recombination was used then to mediate insertion of a late gene promoter and the NANOLUC® luciferase immediately downstream of the coding sequence for this candidate major capsid protein. Insertion of this sequence was not predicted to disrupt any phage genes. A recombinant NANOLUC®-expressing LPJP1, referred hereafter as LPJP1.NL (SEQ ID NO: 2) was isolated, purified, and confirmed using genome sequencing.

SEQ ID NO: 1 LP-JP1 Genome Sequence>2020-01-17 LP-JP1 reassembled vl (223,580 bp)

CCAGTTGAGTTTGACGAAAAAGCATGTCTTCTACATCTACCGGTACATCTGAAATAT CTTTCTTACATT TACTACATGTTAATCCATGAATTGCATAAGAAATACCATATTTATCAGATTGCTCACTAA TCATTTCAC TAAGACTCTTCATGTCACTAACTTCAAGATTACTAATGATCTTAAGAATTTGTTCTGGGT TTGTTACTTT TACAAATTTAAGTTCTCCAGTTTTTTCCAATCTATCTAGGTCAGGAACCATTATTTTTTT AGTGAATAAA ATTAGATCAATATAATCTCTAACTTCATCATAGCTTTCAGGTTTAATATATGATAGTAAT GTTAATTTAT CTTTTAGTGAAGGTATTTGAATATCGAATACCATTTTACTTAACGGCATTTGGGAACGAG TGATCTTAT TTACTGCTGAATACTTTTTAATGACGCTTGGATCTTTAACTGTATCAGTAATTTGTTTTA AACGAGAAT ATGTTTCTTCATTCTTAACAACAATAAGATTCTCATTATAAGCTTTAACATTCCTCATAA CGTTTCCACA TGATCCACACTTAATATCAAAAGAAGTTCCACGTGGGAATGTTTGACAGAATAGTCCGTA AATTAAAG TATCTAGATCATAGATAGATGTAATGTCAATGAATGTATCCCAATCTAATTTACCTAGTG TAGTGGAAT TAATTTTACTAAAGTATGTTTGATATTGACGTAATGTAGATTCATATGCAGAAGCGGTGC TTGATGAGA TAGAAAGCATATCATTCATACGTAGACTCTCTACATGAGCAATATATGCTGATTGATTTA ATGTAACTT GATAAGTAGGGCTTCCTGTTAATGCATATTTAAATTTATCAAAATTAATATCTTTAAATT TATCTTCATC ATCAATAATTAATGAGTCGATATCTTTTAAATTATCAATTTTTGCTTTATCAAGAATATC TTTAACTGAG TCTTTTTTAGGTTCTTGTTTAATTTCAGTTAATGTTTCATCTACTTGTAMGTTGTTAATA TTTTCTTGATT AATTGGGTCTTTAATAGGAATCTCATCACTTGGTTCTTCAAAAATTCCTTTAATCTCTTC TTCTTCTTTTT TCTCATTATCAGGAACATCATCAGGTATTGGATTTCCATCTAAAGGCTCAATGTCTGATG GATTATACG CAAATTGTTCTTCATTTTCTTGTGATTTTTGTTCATATTGATATTGTTGAGTCATTGCTT GTTCGGTATTT TCATTTTCTCCAGTATTATTCGTTACTGAGGAATCTTCTTCTTTCTGGTAAACATCAATA CCTGTACCAG AGAGAGATAAGTTAGGATCAATATTCTCTTCTTTTTTAGCTTCTTCAGATTTTCTACGTT GCTCTGCTTC

TAGAAATAATTTTGCTACATGTTGAGGATCTTCACCTACTACTTGGGCATGTAACAT TGCTATTTCTAG

ATCGCTCATCTTTTTATCGGGAATATTAATATTTGTAGGAATATTGTTATTTTCATT ATTATCTGATTTT

AATACCATTGTATATTTTACCTCCACATAATTTATATTATTTTTAATTATACATTAT TTTTGATACAGTT

GTATTTGTTTTATTATTGTATCCATATAATAATCCAAAGTTTAGATTAGTAGTAGTA TTAGAATCTACTA

AATTAATATCTATATAAAACGTATTTACATTTACGTTTGAATTACTAGAAAGAACGT TTTTAACATTTT

GTATATTAATCTTTACAACGATATCTTGATGTACAATATATGATTCTATTTGATTTT CAATTTTACTTTG

AAGTTCTAATCTAGTTTCCKTATCCAAGATTTCATATAAATATAATCCGATACCGAT GCCCATATTAGG

TTGGTTCGGGTACGTTCCTTGCTCTATTATAATTAAATTTTGGATCTGTTGTGCTAA TGCTTCTAGGTTT

TCTCTTAATATTGGTTGATTGAAGTCATCCCTCTCTAGTATAACTTCAGGTCTGAAT GATATATTTGATT

CATCCGCTTTAAAGTCTGCCATAATTTTCACCACTTTCTATTTAAAGTATTCTATAA AAATCAATAGCTT

TTAATTATAATTATATGTTGCAGTAAAAATTAACATTTTAAAAAATTATTTGTGAAC AATATTATATAT

AAGTTTAGAAAAATTTTTTTCTGGGTTTATATAATACTTAAATATCACTAAATTGTT TAAAATACTCGG

GTTGTAGTTCACATTGTTGACTAACCATTTAAATAATATAATTACATTTAGTGATAT TATACATATCTTT

CATCATAACATTATTCTAAAAAATAATGTTATGATGAATATTGTTTTAATGAACATA TACTTATTATAG

ATATATTAATGCAGAAAGAAGTGAATATTTTGAAACAATTTAAATGTCCATATGACA GAAAGATATTT

GTAAATAAAAAGGCATTATATGATTATATGGAAAAGAATTATTCAGATCAATTAAAT GGACTATCTCC

GGCTAATGCTTATTTTAATATCAAGTATAACAAAACACATGGTAGATGTATTGTATG CGGTAAGAATA

CACCATTTAACGAAACTACTGAAAAGTATGATCGTTTATGTTCAGATAAATGTAAAA TTAAATATAGA

AAGCAGTTTGTAGAGAGAATGAAAAAAGTTCACGGAACAGATACTCTATTAAGAGAT CCTGAAATGC

AGAAAAGAATGTTAGCTAATCGTAAAATTGCAGGAGTATATACGTGGTCTGATGGTA GTAAATTTAAA

TATGTGGGTAGTTATGAGAAAGATGCGTTAGAATATATGGATAAGATATTAGGATTT CACTCTAAGGA

TATTATTGTTCCTTCTCCAATAATCTTTGATTATACGCTTGATGGTAAAAAACATTT CTATATACCAGAT

ATATTTATTGTTCCTTTCAACATRGTGGTAGAAGTAAAAGGTACTAACAATCATTAC CAAACTAGGGAT

AGACGTACTGAAGATGCTAAGGATAAAGCGGTTCTTAAGACAAAGTATCGTTATGCA AAATTAGTTGA

CAAGAAATATGACAAGTTCAATGACATTATTGAGAATCTTAAAGAATCAAAGGACGA TAAAGTCCGTT

AATATAAATAAAATTTTAAACCCTCATTTCAATAATATATTATAATTAAGATAATGT ATATTATCATAT

TGAAATGAGGGGATTTTATTGGAAAATAAGAAACGTAAATTCTTGGCACTGTGTGGA ATTAGTGGTTC

GGGTAAGAATTCTGTTGAATCTATACTTGATGGTTATTATGATAATGTTAATGGAGT GTTTTTTAAAAA

ACTAAATCAAGTAACAACTAGGAATATTCGAAATACTGATGAATTTAATAGTGGAAT ATATAGTTTTA

TAACTATAGATATTTATAATCTAATAAAAGAAAATCTCATTGGAAAAACAGTTATCG ATAATAAATAT

TATTATGGTACGCTTGATACTAGTACTACAGATGGTTGTATTAATACTATTATTGTC AATGCAAAAGGA

TTATCTAATCTTAAGAATGATCTTAATAATAAGTATGGTGAAGATAACTATGACCTA TTTGTATTGCAG

ATTGCTAATAATACTCCTGTGGAAAGAAGAAATAGAGACGCAGAATTTATCAGAGGT GAATATAATG

ATTTAAAAGGATTGTCTAACGCAACTCTTATAAATAATCCTAGTAAATGGTTAACTG TCTCTGACGTAA

TTAACTGTCTTAAGAAAGAAGGTTTTTTGGATACATGACATTAGTTAGTCATACTAA GTTATATGAAAA

AACAAATTATCGTAATAAAAGAATTAGCTATATTAAAAATACGTTGATTACTGAGTT TGATATAAAAA GTGCTGGTCTAAATATTCTATATGAAATGGAATATTTAGACCAAAATCAATATGAAAAAT TATTATCA

ATGGAAAAGTATGAAAGAAACRTTACAATCGGAAAGATATTAAGGTCTAATAAAGAA ATGAATGAAG

CATTATCATTTGGTTTTTCAGAAGCGAGAAGATTATTTTTCGAATTAAATCAAATTG ATGATTCAGAAT

TATTATCTATTAAGAAGGATGCAATATTTCTTATAGGTAGAAATAATATAAATATTA ACGGTAATGTTT

CTGAATTTATAAAATTTAGACCAAAGAAATCTTATACAACGTTTGTTGAAGTGTTAG ACCGAGAACAC

TATTTGAACTTTGAAAGCGAAGAAATAATTTATGATATTAAAGGATACTCTAGTGAT ATTAAAGATAT

TCATAATGAATATTTATTAAAGGATCTTCTTAATGTAATGAAGTTTGATTATGTTAA TGATAAAGATAG

AATATTTGAATATTTAGCAGTTCTTAAGGATGACCTAATTAAATATAGACTTCCAGT ATCATACTATAA

TGATATTAAAGTAGGAAAATATATTGTAGAAATGGGTAACGCATTATTTGATCTAGA TAATATTAATG

ATAATATTAAGCAATATTGCCTGTTGTCTAATAATCTTAGTTTTATTTTAAATCTAA TCAATAAGACTCT

TTCATAAAAAAAAAATAAATAATATATTAAGGTAACGATCATTAATTTGATMGTTAC CTCTTTTTTTTT

TTTTCTATGATCCATAATATACTATATATTTACAGATTTTATTTTCTTGTCAATCGT TAATGATACTTCA

GTCATGATAAGCATAATCTTGCTCATAACATATTCCTCAATATGTTCTTCTGAAATG ATGGTAGAAACC

CTATATTTTAAGTCACTAGACATTCTTTCTACAACTTCATTAGTACATGATATAACA GATTCTTCAAATT

CATCTGTAGTTGTATCGATATCTATATCATCACTAAGTTCACTCTGATCTTCATCAA TAGATGTTTCAGT

AGTCGCAGTATTTTCTACATATTCATTTCCTTCATTGTCATACTGAATATTCATACC ATTAATTGCAGTA

ACTTCACTTAATCTAGGAAGTATTCTATCAATACTTTCAGCAATTAAATTATTCTTT ACTATCCATATGC

TAATATCAATAAGAATATCTAATTCCTTTAGTGCTTTTTCACCATCAATATTATTAT GCATCATTCTATT

ATTACGGTTAGATTTAATAATCAATCTTCCAATAATTATATGTGTAATAAATATAAT TATTAGTATTGA

AGGTACTGTAATGTAAAATAAATTTGTAGTCATCAAATAAACTTCCCCTATTCATTT ATTATTTATATA

TAATTATTCATACTAAAAACTTGAATTTTATTTTCTTCTAAGAAAGATACAACTTCC TGAGAATTATCA

TATTCTTCTAAATAATATACTTTAGATATTCCTGAAGCAATAATCGTTTTGGCACAA TTAAAGCATGGT

GAATGAGTAATAAACATTCGATGCGCCTTCTGTATTTCCAGAGTTTCTAGCCACCTT AGATATTGCGTT

TATTTCTGCATGTATTTCATATTTTAATGACCATTTATGATGAATTTCCATATCTTC ACATAAATAAAAT

TTCTTTCCTTGACTTTCAATATAATAATCTTTGCGACAAATGAAATACGATTGTGAA GTATACCATAAT

CCTTCTTTCTTTATGAATATATCATTACAGTTAGCGTATCCACTAGGGGTTCCATTA ATTCCTGAAGATA

TAATGGAGTTATTCTTAACAATAATGCAGGAGACTTTCTTTGCAGAGCATTTACTTA TTTCTGACATTC

TTATTGCAATATTCATAAAGTTTACTTCGTTTGTCGTAAATAGTCATCCATATTATT ATCTTCATTATCT

ATAAATATATCTACCAAGATATGGCCACTGATCTTATTCTAATTATAATAAATTATT TGAAATGATGCA

TTGTTTAAATACTTTTAATTTTCCGAATGTTAATGTTAATATCAACACGATTTATAA AATTGTCAATTTC

TGTATCTGTATTAGAGAACATATTTTCAAAGATATCAAACTTTATAATTCGATAAAA GCTATCTTGACT

TATATAATGTGCAATATTATTAACAATATTATCATTATCTGTAAGATAAAGATACTT CACAACAAGACT

AAGCGTTGTTAATATTAGTCTGTATATTTCTTTTATACGATAATCGTTTATATTTTT ATCTATAATTAAC

GTATCATATGATTCTGTCTGGAAGTTAAATTTATATGTTTCTTGAGAATTTACTTTC TTCATCAAACTAA

TTATAGATACTGCGTTTGATGGCATTTTTTTCACTTTTGGAAATATCAATTCTTTAT TATTTATTCTTCTT

TTTGTATCTTTTATTAATTCATCAATAAATTTTGAAAATTCGGCATTATATAACTCA TCATTACTTAGAT

CCATATTTTTTTGTAGTTCAATATACATTTTAAATTCTAGTTCCAATCTATTTAATA TATGAACTTCATG CTTTGATAATAAGTTAATATATAATACGTTTATTGTAGGAAATTTAATATTGGATTTATC ATCAGTATC

TATATCAGTGGATTCTATATAGTATGATGAGGGTGAAATATAATTTTTATATTTATA CATATGCGTATA

TGAGTAAATAACTAATTCATTAGTATACGTAAAATTCATTAAATTATCATTATCATA ATTATCCACTTC

AATATAGTTGTTTATTATTGCATCTTTTCGACTGATTAACGATCTTTCTTTATTATA TTTGTGCATTATA

AAAGAGATATATCTATTATTATTTATATAATTAGATGAATCGATAAACATGTCATAT TCTTGTAATTCT

TCAAAACATAGTTCTAAAATATTTGCAAGCAATATTTGAATTATATTTCTATTATCT TTTATTTTATTAT

AACCATAATAATTTTTGTGACTTATCATAGGAATATCTGAAAATATGATGTAATTTT CAGAAGTAAGA

AAAAAATTAGAATTATTTAAATCATTGAAGATACCAGTAATTTTACTGATATCTTCA AGACTTATATTT

TTAAATTTTTCATAGTTCCATAAATTTCTCACTTTAATATTATGGTTAGCATCAGTA TAGAAATATTTAG

TATCAATATTCATTAACTAATCACTATCCTTATATAATATTTTAGTATCGATATTTA CTTTTGTTTTTAA

AGTTAACGTCTCTTACTGTTCCTGGAGGATTATTGATTGATAATCCTGCATTATTAT TACTTTCTGTAAG

AAGCCAGATAGTATATCCTTTAGGTTTCTTACAATCAAGCGTATTCTCACCAAAACC ATCCGTAATAAT

AATATTAATATCTGATCGAATATTTTCATTAATATATTTAATTGGAGCAGTCAATGT AGTTCCACCATA

AGCAGTTCTTTCAAATTTACGTAATCTATCTTTCTTAGATAACGGATATACATCATG AACCATTGTATC

AAAGTGAATTACATATAGTTTACTTTTAATATTTGAAATAATCTGACGAATTTGATC AAAAGCCAAAG

CCACTTCTTCGTCACTCATTGATCCTGACATGGTCGATAGCTACGGTAATTTTAGAT TCACATTCGACA

TTCTTCCTAATAAGTCACCACGATCTGGCATTCTTCTATTTCTACGCAGATTAGTTC TTTTATAAGGAAC

TTTTAAAGAACCAATCTTCGTACGTAAGATTTGTTGCCAAGGAATAACTTTTTCCTT ATTAATATTTTCT

AGAAATTTATTAATAGAAACAGGAACTGATCCGGCTAAAGATAGTCGTTCAATAGTA TTTTCGATATT

TTGTTTTATTGAACGTTGAATGTCTTCTTCAGAATAATCGCCGTTTTTCCATTTTGA GTGAGAAGAATTA

GCACTATTATTCATGTTAATGCGTATCTTTCTTACCTTCTGAATCTAATTCATTACC TAGATCATTTTCA

TCTTTTCCGTATTCATGAGATTTGCCAGTATTACCATTAGAAGAACCTTCTTCTTCA TTTTCGCTGTCAT

TATCTCCACCATTATCAGTATCAGATGAATCATCATCATTATTCCCACTTTGATTAC TTGGCATTCCATT

ATTATTTTGACCGCTTTTATTATTTTCATTAGCTTCTAATAATGCATCCATATAGTA TTCAAAAGATTTA

TCTTTTTCCAAATCCTTATTATTAGTTAACATTCTTACATAATCTAGTGTAATAGAA CCTTCTGGAATAT

CATCAATATATTGATTAATAGAACAATCCATAGCAATATTTGCCATATGCATGAAGT CTTGATTTTTAC

TAATCGACTTATTCTTCAATATCGGAAAATATGATTATTTGAAATATGAAGTAATTC ATGAGTAATAAC

TGCAATGAATTCTCGATCATTAAACATTAAAATTTTATATGGATTTAGATATAATGT AAATGTATCTTT

AAATGTATTTTCAGCATAGCTAACTGCTGCCGGAGCAAAGTTCGGATCATGAACAAC TTCTTTAATCAT

ATTAATTGTAAATAGAGCAAAGAATTTGTCATCATTAATGTTATCACTAATTAAATT AGTGAATGTTAA

CTTAATATATGCTTCAAATGCTTTTTCTAACTTTTTTGAAGCTTCAAGAGGTAAAAG CTTCTCCTTACCA

TAATATTCAAGAAGAAACTTTTTTAATTCTTTTCTAGTCATACTATTAGAATTATAA TTATCTAAAGTA

GGCATTAATATCCTCCACCGATCTAATTATTTTAAACGGTTTACTAATTTTTTGATT GATTGCGATATAT

TCATCATATTGATAAACTCTGTTATAGAAATCATCTGCAGTATTATTTACGAGTCTA ATTAACATTGCA

AAAGTACTCATGATAACTTCTTCTTCTCCCAAAGTATCTACAAATTTAATATAGTTC GCAGTCATTCTA

TCTAAATCTTTTTTATTTTTTACTCGTTTACTATCGTTACCCATTTCACGAACAACA TAATTAATTACAT

AACGACTAAGTAGTGTTTTACGTAAGTTTGTTTCCTCTTTAATTTGGGTCAATAGTT TTTCATCTTTAGA TAAGTTTGGGTTATCGATAATCAATTCAGCTCGGATCATAGGGTTTGTTTTGTCTTTTAG GAAATTAAA

GAATAATGAAGTAGCTTTCGAACCTAGATTACCTTCAAACACTGCACGTAGTTTATG ACTAATAGATA

CTGTATCTTCTGGGAATTGTTTCATATGTTCATAATACGCATCAGAACTACGTTTCC ATGAACGTGGAG

TAGGTGACTTACCTAATGCTTGAATTTTCTACAAATGACAGCAACTCAGGATTTGTT GCAATAAATTCA

GAAATATCTTCATGAATGTTTGGTCGAATATATAGTGGAGTAGAAGTATTTGCATCT ACATATTCAAAT

TCTTGAATAGCCCAATCTAACCATTCTTCTGGATCTGGATCTAGTCTAAGATCTGTA AATAGGTTATGT

AGGGCATAGTTCATTGTGTTTACTTGATAATCAATACCGTCACTGTTTTCATCTGTA GGATTTCCTGCA

GTAATAATATATAATTCTTCTGGAAGAGAGTATTGATGAATTCTCCGATCAAGAATA ATATTCATTAAC

TCTTGTTGAACAGCTAAATCTGAACGGTTAAGTTCATCGATAAATAGTAATGGAATT TTTCCATTATCT

GCAATCTTATATAGTTTACCAATTGTACTATGAATAGTATATTCATTTTCTTTAGGT TGTTCTTCATTTTT

AAACCATGTTTTGATATTTGTAAGTTTAAATTTATTTTTAGGTTCTGCAATATGAGG GATACTGTTAATT

TCTCCTTCTTTAAGTAAGTTACCATCAAGCTTAACAAACTCAATTAAGTCACCATTT CTTTCATTATAAC

GTTCAACAAATAATTAAGCCAAACTAGATTTTACGATCCCTGCATGACCTTCAATAA ATGGTACGCTTC

CTGAAGCTACCACTACGCCTACTACATCTAACAAGTCTGACATTTTCATAAATAAAT TCCACCAATCTA

TATTTTTTATTTTATTACTAATTTATAATATATATTTATAAATTATTTATAATTGTG TATATCACGCTACT

AATTTTGGTTAATGTTTCTTCAAGGTTTAAAAATGAAGAACTTTCTTATCATCATTT TTATACTTCTAAT

GCAAGATTGTCAAATCTATGATTATATTCAATAAAGTGAGGAAGTAATTCTTCTGGA ATATATCGATTT

_{CTTTTTGATGTACCTTTTTTAAATGAATTAGTAGTATGTCCTTTAACCCACGTAA AATTAAATTCATATT}

GAGAAGAACTATTATTAATAATATTTACTAATAACTTCCACATCTCAGCATTCTTTA CTGGTGTTCCTG

AACTACTCATCCAGTTTCGATTAATCCATCCAGTCATATATTCTGTAATACCTCTGA TAACGTATTGAC

TATCTGAAACAACACTAATATTAAACTTTTCTTTATTACCATTCTTATAATTATCTC TCATAATATGCGC

TATTCCATAAATAACGGCTAATAATTCATTTTGGTTAATTGTTGAATCATGAAAAGA TCTTTTAATACT

GTATAGCGTATTAAATTCGGTGTCAGTAATATAGCATCCAAATCCTCCATACATAGG CTTACTGGGGTC

TTTCCTACCATTATTAAAGCTACTTGCATCCGTAAATAAATATATGTAATTTGTATT ATCGTTGTCCAAT

ATATTTTCACTCCCACGTTTAGTTATTTCTTTTCGCCTATATTCTATTATTGTAATT CTAGAATAAAAAA

TTAATTATAATAAACAATATAATATAAGCACTTCTATAAGAAAGGTCTGATATTTAT GAAAGTTCCAA

ATAAGAATATAATAAATGATATTATAGATAAGGAACTAGAAGAAAATAAAACATTTG TAGTAGATAC

TAATGAATTTGATACTGAGAATATGATCAATAGTGTTGTTCCTAGTGAAGAAAAATT TAATAAAGCTA

TTGAAAAAATTATTCGTAAGTCTAATGAATATCGTAGATATATCGGAATACTGAAAA ATAATATTGAT

CTAACTTCTTGTAAATTTTTGAAACGTGTTGATGTTTCTGAAATAAGAAGAGTTAAT ATTGAAATGCAT

CATTACCCATTTACTCTCTATGACATCGTATCTATGCATCGAGAACGTATCAAGCAA GATTTAGGTGAA

TTTTATTCATATGATACATTCACAATTGCAGAAAATATTATGAAAATGCACTATGAG AATAAAATCGG

TATTGTACCTTTATCATATACTGCTCATGAATTAGCTCATTCCGGAAAACTAGTTAT TCCTCTTAATAAA

GATTATGTCTTTGGTAACTGGCAAGAATTAGAAAAAGAAGATATTATTATTACAGAT AGTATGCGAAA

GCAACTAGAAGTATTAGAACAAATGACAAATAGTATTGAGTCTGGAAGCCTTAACTC AAACGAAGAT

CTATTTAGTAATATTCAGACTGTAATCAATATGAAAAGTTCTGGAATACCAAATAAG ATTATAAAGGA

AAAATCAATCATTGAGGATATTAATAATCCTGAAACTGATGAAGATATAATATAATA AAAATCCCTTA ACGTATAATAATACTATACGTTAAGGGATATAATGTTATATTATGATTTTTTGCCATTAA CTTGATCTA

ATAACTTATATATGAATAATTCTTTATATACTTTCTGATCTCTATTATATTTATCAA TAGTTGCTTTTTCA

TCATCAGAAATAACTTCTGTACTAAAGTCTTTAACTTTAATAACCATATCTAACTCT GTGTTTAAAGAT

TCTGATTTTAATACGATATGGAATAAATTTATGAATTTAGTATTTTCACCTTCAATA AATTCATAATTAT

CTAATAAAGAAATTTTCTTATCAACATCAGAAGAACTAAATATTTTTCCAAAGAAAT CATCAATATATT

GATTAATTGATAGTTTAATAATTTCTTCTTCACTATAATTTTTATTAGTTGGAATAT CCTGAGTGTACCA

AATTTTTTGAATTTTATCATGGAGCAATACATTAAATACGCCCGGAGAATTTACCAT AATATTGCTAAC

AACAAAGCTAATACTAAACGTATATACCTTTGGCTTAGTTTCTAATTTATCATCTGA GTTACATGATCC

TTCTGATGAAGTAAAGTTATAAAATGTATTAAATTCTTTTACAAACTGAGCATATAA TCTTTCAATAAA

ATTATCTTCAAAAGGTCCAAAATCTGTACTTAATGGAAGTTCAAGGTCTCCACTCTC CATTAAATTAAT

TGCTTCTTGAATTGATTCAATTAATATATCAATCTTACTATTTACTTCATTATCAAT ACGATCAGTTACA

CCTTTCGGACCATAGATATTTAACGTCATATATTCATTATTGTTATCATTCTTATTA AGTACGTCATATG

TTACACTAGTAATAACTTCACAATTACGTGAAAAATCCAATTCTTTATCAGTGATAT CATCTAAATCTT

TGATATCACCAATAATTCTTAAACTAATAGCATCCTCAATATTAGGCATCCTAATTC CACATCCATTTC

TTTTTATTTGATAATAATTTATTAATAAATAAATATAATTTTTTACATTCATTTACA AGATTATACATTC

CCTATAACTATGATATATTCAATAGTTATAGGGAATGTATTTATAATTAATTAGTGC ATTGTATTAATA

TATTGTATATACGATGAAGCGTTATCCTTTATTACATTATCATGTTGTCTTATTTCA TATTTCGTTAACA

TGATATTAATGAAGATATAAGTTATAATAAAGAATATATAACTAAGTATTAATAGTT TTAATAATAGTT

TATTTTTAGTTCGATTATCTTGGTTTTCATCAGTATCTATATTTTTTCTTAAATTCT TCATTAAAAAGTCC

CCCTTTTATTCTATATATTATATTGTTTTTTAATAAAAGCGTAATAAACGAATATAT AGACATATATTAT

AATTATGATAAAATAATAAATAATATAAAGAAAAGGATGATATTATAATGAAAAAAT TTGTACAAGT

ATTATTAGTAGGAGTTCTATTAGCAGTAGCAGTAACAATTGTAACTATTAACGTTAC AGAAAGTAATA

ACGGTACAATGCAAAAAGAATTATTACCAAAAGTAATTTTAAATAGACAATAGTATA ATTACTACTAT

TGTCTATTTTTTTTTTTAGTTGATTAAGAATATTTTATCATAATCTAGATTATCGTT GAATTCTAAAAAG

AAGTCCCCAACATTACTTACTGTACATTTTCTAATAGAAGATACTCCTTCATCTATT GGTGTAGTCTTAT

TTACTTCTAGCTCCATACTATTATCACTATAAACTCAGGATAGATATTTTCCAAGAA TAGATAACTTCT

ACATTTTCTTCATTTAATACTTTTTGTATCATGTATAAGTGATATATATTGTCATCA TCCCTCTTCATATC

GTTTGGGAAGATGTATCCAATAGTTTTATCATTCTTATCAAAATAAAAATTTTCCAC AATAAATTCTTT

GACAAGATTAGTATTCAGTAATTCAATAGCGTTATTTAAGAAATCTTGTCTAAATAA ACCTAAATTATG

AATATTGATTTCTAGCATATTATAATCCACACCTTTTTCTTTTTTCTTTTAAGATAT TAATTCATTATTAA

GATAAATGTTTACACTAAAGTCATCTTTAGAAGTATTATTTATTTCTAACGTAATAA TGTAATCATTGT

TAGCACTATAAAAGATGTATTCTTTTATATACCTAAAATTATGTTGTTTATCAATAA ATGAATCAATCG

TGTTTGATGTAATATCCCCCTTATAATCTTTGATATAATTCTTATCAAAATATATTT TTGCTTTATATAT

CTTTTCTTTAATATATTCAAAAGATTCTTTGTTATCTGCAGTAATTGTAACTTGATT ATTTAGAAATTTG

TTATAATCAATATTAAGTATATTTACTTCATTATGATTATAACAAACGTTCCATGCA GTAAATATTTCTT

TTGAAATAAACTCAAAAATATTATTATCCCCACTGTTATTCATAATAAATTTCCCCC GATATATTTATTT

GATATAGTAAGTTTTATTCTAATATTTATTTAAGTTTATAATGATATATTATAGATA TGGCAAATATAT AATATATATTTTAATTTTTCATTAACAATATTTTAAGGAATAAGGAGTGCTGATTAATGT ATAGATATA

TACGTACAAACGGTTCTATGCGAAATAAATTGAAAGAAATGAATATTGATAAGAATG ACAGTATCTTT

GAAAATACTGTTAAGATTATTAATGAATTAATAAATCATTTCTATTCAATAAGTGAA GTATTTAACTTC

ATAGAAAAAGAAAATATTCATATCAATAATGAAGTGATGCAATATTTAAGTTCTGAT GAATTTTATAA

ATCTGCATATACTTCGAAAATAATGATGAAGAATCATATGTCTAAACATTCATTTAT TCGCATGATAAA

AAATGAATTGTGTTATCGTAATATTAGTTTTATTTTTAATGATTCATTATTTACTAA TGATGATATTGCC

ACGATAATAGTTAGGAATGATCTAGCTGAAATACCATTTGATATTATGGTTAAGGAA AATCCATTAAG

CTTGAAAGATTTTAAGAAGACTTTAAGATATAATAATTTAAATGATCATGAAAAATC TATTTTAGAATT

ACGTAATATTTAAATTTATTAAGAAAAAAAAAAGATAACTATTGTAATTTTAATAGT TATCTTTTTTTC

GGATCATAGAAATATTTTATATATTATATAGGATAATCATATTATATATCTTTAATG ATGATAATCTGT

TGGCTAATTCTGGACTTCTTTTCTCTAATGAATAGATATCGATAGCTTCAATAAGAT TAATTACTTTAAT

AAATCCTAGATTTCGATATCTTTTATTTATTAAAACAAAATTAAGTAATTCTATGAA TTGTATTAATCTT

TCAGCATGATACAACGATTTTATTTTATATTTTTCTTCAACATCAGCGAGATCTAAT CCATATTCTTTGT

AGTAATTTTTCTTTAATAGCGGCTTCATCCTACGTATCATGATACTAATATATCTAT TAAGTTCATTATA

GGTAGTTTTAGTATTCTTATACACTGCCATTTTATGAGTTTTAAAGTAGTTATATAA GTAATCTATTATA

TCATTAAAGAAATATTCGTTTGCATAAATAATCTTTATAAAACTAGACTTTGGCATA ATAATATCTAAT

ATTTTAGGGTTAATCGTAATCCGAGTATTTTCAACCCTTGATAAGAATTTAATATAT GTTTCAGTTATA

AATTTATATACAACTTCTGATTCAATATTAAACTTTTCACAAAAATTACATATGACA TCATTGATATCA

TACTTATTATCACAACAGAAGACGTAAGACGAAATTGTATACAATAATATATATTCA GTATTATTATTA

TTACTATGACTAATATTATCATATAAATCACTTATCATGATCATCATATTTTCAGGT TTAATATCATATA

AATAGAATATATTTTGATAGTATGATAATATTTGTTGACTTTTACGTTTATTATTCT TTAATAAGTACGT

AATAATATTCATAGGTAATAATGTAACCGATTCCGTATCTTTTTTATCTAATGCCCT ATTATTACCTAAG

TATGATAAGATATCGATAATATCACCAAAGTTAGAAATATCATTGTATATATCTAGT ATACTTTCAATG

TTTTCATTTAATGACATTGGTTGTAATTTATATTTATACGTTATCATAATTTGTCAC CTGTATTCTTTTCA

ATGATATTTCTAATTTTATTATTAGTATATTCATCATTTGAGTAAATTCTAGGTAAT ATCTTTGGTTTAT

TCTTATTAGAAGGAAGATTATCAATTATTGAAAAAATTGATATTACTTTATTAATAA TATTTATAATAT

TGGTATTTTTAGATTTCAATAACTTATTAATGTCATATGATAATAATTCATTATCAC TATCAAACTTCTT

ATAGAATGTAAAACCGTACATATTAATATTATTTTCTAGTAATATTAACGTATCCAT AATATTATTATA

TCTTACGTCATCCAATTTATCTGAATACTCCGTTCTCATAACAAAGCTTATTACTTT AACAATAAAATC

AACTACGTTATATTTATTTTTATATCTACGATATATTCTAGGATAATTGAATATAGA ATTGATAAAAGT

TGTATCTTTATACGTTATATAGGATACTGATATAGAAGGGTCTCCGGTATCAATAAT TCTAGTAATATT

TTCATATTCATCATCAATTATATTATCATTGTTAAGATATTTTAACAATATATATTC AATATATAGTAAA

TTCATATTTAAAAAAGGATCTAATATACATTGAATTTCATTAAAATTTTTAATATTT ATATCATATCCCT

CATACATTATAATATTTTCGATAAACCTTGATTTTTCAGTGCGAGAATAATCTTTAA TTTTACAAATATT

_{ATTTTTTGTTAAGAGACATTTATACTTCATTGTATTGTTATTAATAACCATATCC CTAAAAATTTCTTTT}

GTATCTTTTGTAGGTTGATCTACATATTTAGAAAATTTACGATTAAAATCAATTGTA TCCCTTAATGATT

TTGGATTATAGGTTCGTGAATTAATTTCTAAATATTCTTGAATGTCTGTATTAATTG ATATACTATTTGT CACGCTATATCACGTCCTATCATTTATTATATGCTTAACAAATTAATTCGGCTTTTCATT AACTTACATA

ATTCATCTATTCGTTTAATATTATTAAGAGTGTTCTTTCTTATTAATGAATTATGAT TATCCGCACTAAC

ATTATCTTCATATCTTCTAAATAATTCATAATTATTATTAGTATAATCTATAGAATC CAAAATTTTAATA

CGTGCATTATTTTTTACGCTAGTCATTTTATTATTATTAAAATTAATATATAAGTTT AATAATTCAAAAA

TAATGGATATTCTATCAATACTGCTTTCAAATAATATTAGATCATCTTTATTGTTAA AATTAAGATATCT

AGATATTCTTAATGCACTATGAGGGTCTATTCCGATAATACTGTTAATTGCTTTTTT ACTATTAAGTATT

ATATCTTTCTGATTATCTGTAAAAAATTTAGAATAACCACTACCATATATTGTATTG AATATTTTAGCC

ATTGATGATTTACTAATAAATTTTTTAAAATGTTTATCATCAATATCTCTAACGCCA TATATCGCACAG

AATAGATTGGTTGAATATAGATTCATTTTGTCAATCATAGTTAAATATTCATTATCT GTAATTGTAGAA

GATTCTGAAATGCATGTTTTAAACTTTTCAGATATCCTATTTCTTATACCGAAGTCA GGATCATCGTCA

TTGGATATATTGTTATATGTGTCAAATAGTCTAAAAATAATTTTTCTAATGTATGAA GAGTTTATTTGT

AAATTACTACTAGTATACTTATACTTCTTACTAGATGGTGATATAATAAAGTCAATT AAATCGTCAAAC

AGTACACTATACATGGAATTATTATTGATAAATGAATCATATAATTTGTCAATATTC TTCTTAGTAATT

ATATAATTACTATAATTCATACTTCTTTTCGTATATATATGATTAATATTAACATAT TGAGTATTATCCA

TAAAAGTACTAAACAGTTTATTGTATATTACGCTTGACCTAATACTATATTTAAACA TAATGTAATCCT

TTCTTAAATATTAATGTCCTTAATATAATGACGTAATAATTCCTCGGATATTCCTAG TTCCTTAGACATT

ACTTCAATAGGTTTGTTAAGATTCTTTTCAATATAGTCTGTTATATATTGTTCTGAA CTACGTGAATTAC

CTACCTTAATATCAGTAGTACTTAATGGCATTTTAAACCCAATAGTTCTTGGGTTAG TAATTTTTTCATA

TTCGGGAACTGGATCATTCTTAATAATATGGTCTGGTAGTTTCATATTATGTTTTTC TAGGCTACAATTA

TCCAATCTTTTAAGTTTATCTAATGATTCATTAGTAATGATAATCATTAGATCGTTT CTACTTAGGTCTA

CTGACATTTCTTTCACATTTTCATCATAAAGTAGTGTAGACATATGACTAATAATAT CATGTGAATTTT

CCAATGTAATATTTTGATCCATATATTTTCTAATATATTCGACTAATTTTTTCTGCA TATTCCGATTCCA

CCAATCTATATTATTTATTAGAGATTATACGTATATCCATTCAATTGTTAGGTTGTT TAGAATTACCTTC

ATTTAGTTTTATATTTAATACATATTGAATATTGTTTCCTTTATTAAATTTAATGTA ATACTTAGTCATA

TCACCAGTAGTATTATTAATAAGTCTAATTGAATAGGATTTCTTACTATGTTTATTA ATATGAGTATAT

AGATTATCTTCATCCTCTATAATGATATTCTTTTCTGTAAAGTAATCTAATATAGAT TCTATTCGTTTTA

ATTTATTCATCCTTATCGATAATAATATCGATAAGGATGAGAATAATATAGTTAACA TGATAAATATA

ATCATATATCCATCGTTCCTTCCATATCTATTTTATGGACATTCATTAAAGTAATAT CATACTTTTTAAC

TTCAATATCAATTGCAGTATAGTTTACCATAAATGTATATCGATTCTTTCCAATTTT ACTAAGACTATTA

TATATCTGGATTGAATATTCACGGATATTTGGAGAAGTTATTATATTCGTATTCATT TTATTATCATATT

CAGTTAATTTATCAATAATTGAGTATGATAACATGATTTTTTTATGTACAATAGATC TGTACACTATTG

AGACTATAAAGATTATAATCATAATCGATAATAATAATATCATTTAAACATCCTTTC TTATATAGATTT

ATTTAATTTTTTGATTACTGATATACACAACTTCTTTAAAGTCTTCATCATATACTA ATTCAAATTTATC

GTTATTGTAGAAAAAAGTGTATGTATTATGAGTCCTATTTAAAGATCTTTCACAGTG ATATAACAGATC

TTTAAATACATTTTCCGGATTTACATAAGATTCCTCCATAACATTTTCATATCCAGA AAGAATTAAATA

ATTTCTAATGTCTGGATAGACTTTTTCCTTAAGAAACTTTGGATCCATTCTTTTTCT AAATTCAGCCCCA

AGAATATAATCATTTATAGAATCCATTATCTTATCAATAATTAAAAATCCGATTAAC ACTAAAAGTAAT ACTCCTACAATATTAAATAATAACATAAATTTATCACTATCCTTTTCTTTTTATATATAT ATAAAAATCG

ATATCACTCCATTATAGTAACAATTATTGGAGTGATATCGATTTAATTTTAAGTTAT ATACTAAGAATT

ATTTCGTGAGATAAATATTTCTTAGTATAATGAAATAAACATGCTTTAGACTAATAA TAAGATAAATTG

TCAAGGGGAATTTGATCTTTATACATTATTTTCATTTAATAACAAGTTTATTTATAA TTCTAATTATTAT

ATCAGAATTATAATATATTATTAAAATGTAACTATAAATTTTTATAATTATACATTG ATAATCATATCT

ACATTAATATTTTTCTGTTGAATCATTAGATTAGAATTCTTTAATGTATTATTAATT TTATTAATATTTA

GGTTATCCGACTCAATATATTTGTTGATAAATACATCAATGTATGCTTTTGGATTAT TCATTGAATTAAT

AATCGTATCTTCCATATTATCAATAGGTTTAGGAGATATGACCATATTGATAATAGA TGACATTTCATT

AGTCATTCCCGCTTCAATAGTAATCTTATCAAATATATTTTTTTCATCTTTCCATAA GGTATTATCAATA

TTCATTTTATTAATATTGAATTCTTCTAAAATGAAACAATTGTTTTCTAATACATCT TTTATTTCATGAG

TTAGAGTGATAACGTTTCTTAACCAAAAGGAACACTGTTTATTAAGTTCTTCTAGAA TTACATTCTTTT

GAGATATATTTTCCCTTAATTCATCAATATCCTTGGTGTAGTTATCATATCTATTTT TATATAAATTATA

TTCATCCATATTGGATTCTTCTAATTTTATATCCATAATTTCAGAAACAGCATTTTT TGCATCTATAAAT

TTAGATATCAATTTTTCAGATCGATTAATAGTGAAACCATTAAAATATTCTTTTGCC TTACTATTAATAC

ATAAATATGTATCATATAGGAAATTAATAGTTTTTTGTCTATTTTCCCTTAGCGTAT TAAGATCTTTGTT

ATTCAATGATTTTCTAAATTTAACTGCTAATTCATAATCATTATCGATATTTGTACC TTCAGTGCTGATG

ATATTATAATAAGTAGTAGTATTCTTTTTTAAAGGTTTATTGATAATATTTAACTGA AATGTTCTAATTT

CCTTCATACTTACTCCCACCACCATTATTATCTAAATATTTATCATACTAATAATAT TATCTAATTTTTC

ACTTTTAACAATATTTTCATTTAATACTAAAACATCATTTATATATGGAAAACATTC TGTAATGTGTTTA

ATTATAAATTCTGACGTAATAGATCTTTGATTCATTAGTACTTCTTTATGATTTAAT TTATACCAGTATA

TTTCAATAAAGTCAATTGACAACTTTTGTCTTCTTGATATAATATCCCAACAATCAT CATCAATATATA

CTGATATAAGTTCATATAGCGTTTTTTCATCAAGATTAGCATAATAGATATTCTTCT TCATATATTGGG

AAAACTTTATTAAGAATTCCTTACTATAGTTACAATGCATAACAATATGACTATCCC AAGGAATAAAA

TCTATATTTTGAGAGTATTCTTCAATTGTCATGTGTTTGTATATACTATGATCAATA TATTCCCAAAATA

TTTTAGTTTGGTTTTTAGTAATAAATTTCATATACATTTTATTATATTTCACCCGAT AACTAAATCTAAA

CCATTCAGGATCATTTATATCTTCTTTTTTAGTCATATCAAGATTAAATAAGACCCC AATAAATAATCT

TAGTTGATTTATAAATCGACCTTTATACGTGTCCATTATATTCAAGTTATTCTTTTC CTTTCTTAATATA

ATTATATTCCATTTATATATTAACTATTTATTTTATACATATTAAAACCCAATAGAT ATATAGTAAATAT

CTATTGGGTTAGTGTTTTATTCAGAGATCTTAACTGTACATACTAATGGATTATGCT GTAATTCACTAA

CTAATTTAGGAATAGTTGTAAGTTTATATCTAATAGATGGATTTTGTTTTTCTTCTT CCAATATACTAAT

CGATTCATGAATTCGAATAATTTCTTCACGACTAATTGGTTTAACAAATATTGCAGG CTTACCAGTATT

AATATTGATTCCCTCAATAATATTCATTTCATCATGACTTGATAAGTAACCCACAAT AATCTTAATATT

TTTTAAATCTTTATACGTTAATCTTGTTTCTAATAATGAATCATCTTTCATTACGCA TAAACTTCCCTTC

CAGTTTAAGTTTTATTTTATATAATTATTAGTTAAACTAGTATATAAAAAATTAAAC TGAATTATAGAA

TAATTTATTTAAAAGAATATAACGTACCTTTCATATCATTATAATAACTATATTTAA TCGATTTAAATTT

ATCCATACTATTGAAGAAGATAAATTCCGGAGTATCTTTCTTAGGAGGATAGTTTAC AATATCAATAAT

ATGAGCGATAACTTGCATATCCATATCGGTATATTTAATATTAGATAGTTTTGTTTT TGATCGATTTACT GTAGTTTTTCTAGTCCTTTTATCAATGTAAATAGTAATTTCTTCGGGATTTTCAGTAAGT TCTTCATGAA

TTATATTGAGAAAATTTACCGCTTGAAGATACGGTACTAGCGATATTTCCATTGTAC TATTAAAGTTTT

CTTCATTACTTTTAGAGTTGATCATATTTTTAATATTTTTTAGTTTACCTATTGTTT TTAACATTATAATT

TCCACCTTTAATTATTTATTTGTTGTTATCATATTAATAAAAAATGTATAGTCGATA AAATTAGACCCA

TTGTCTCTAATAATTTTTACATCATCTTTAAAATTAACATATTCTTTAATAAAATCG AGATTATGGGTTT

TTCCTTTAATCGATTTTGAGTCAATATCGTTAATTGCAAGATTTCTTATAACGTATG GACTATCTTTAGA

ATCATAATACAAGTTATGGATTCTAAGAATAAATATACTATTATATAAATTTTCTTT TAAGAAAGATAA

ACTTTCAGTGAATCCTAATTCATGAGTCTTATCATTATATCCAGTAATATGACCAGT GCTGACATGTCC

ATTACTATGGATAATTTCAACTTTATTATTAATTAATGATTCAATATTCGTTTCGTT TGTATACTTATCA

AAAATAGTATGATTAGACGCATTATAAATATTAATATTCATATCGTCATCAATTGTA TAAATATATTTT

TTTGAGATAAGTTTATCGAGAATTAATTTTAATGTATTTTTTCTTAATTTAAATAAA CGCTCTTTTAGAT

AACATACTTTATCAATATCCGGATACTTTTCTTTTAGTGAATAATCTTTATTGATAG TATTAACGTCAAT

ATATGATATGTATTCAATATAATGAAGATTAATAATATCATTATCATTAAATGATGT TAATTTCTTTTTA

ATTGTAGTGATATTCATTACTTCATAGTAAATATCATTATTAATCTTTTCTTTTAAA CTAATAATCAATA

TTTCCTCAGACTTATCATTTGTAAATAAGAAACCTAAATTGCTCATAGCACTTTCAA TAAAAGAAATAT

TATTATCCATTTAGATTTACACCCTTTCTAATCTATATATTCATTATAGTTAATGCA TCTTTAAATTTTTG

ATCTTCATTCATATATTTAATTAAGTATGGATGTTCTTTAAATTCATTATCATACTT AGTTAATTTATTA

TAGTATCTAATAATAAATTTTTTTGGTAAGTTTTCTTGACTTCTCGATATTTTGAAC CATAAATTAGCAT

TATCTAAGGGTACAGTGCTTAGTATATATTCAATTGATACTATTGGTAATTGGTATC TTGAAATAGTCA

TTATAATTGTGTGCAAGTCAAAATATTCTATATATTTTAGTATTACGCTTAATTCTA ATTTATGGTTTGA

AACGATAATATAATTCCAGAATAATTTTGGAGCATATTTATCAAGAGAAATAATATT ATCTATTGTTAC

ATCATACTCAATATCGTATTGAGAGAATATTAATTCTGCAGTTATATTTTCCCAAAT TTTAGTATTAAT

ATCTATACTGTCTGCATACTTAATAAATAGATTAATATCGTACAGTAATAGTTTATA ATTATATCCTAT

GGAAAAATCTATATTGTCAAGAATATTAGGATTATTTCTCGATATATCTAATATTCT ATTGCATATTTC

AGGAATATTGTGATCATATTTATATGAGTTAAATTGAGATTCAATAAAAGAAGGGTA GTAATTTTCTTC

ACCAGTATCATACTTTTTATCAATATCTATAACTAATTTAATTATATCGATTTTTTC ATTCTTTTTAGAA

ATAATAATTTTTCTTATATCTTCGTTACTAATAGGCTCGGTATCAGTTCTAGACATA ATATTCTAACAAT

CCTTTCTATTATTAAAAAATAAAATCTGAGACTATAATTGATCATATAGTCTCAGAA ATATTTTATATT

AATCTTCTAAATTATTATTTAATATATTCATAGACATATTAAAAATACTTCTTGAAC GTTTACCGATAC

GATTTATTGTTTTTTCAGATATATTTAAATAATCTTTAAATTTTATCGGAAAATACT TGAGGTACATAG

AAATTTGTTCTGGATTATCAATAATATTGTTATCAATGATAGTTCGAACAACAGTAT AAATTTGACCAT

TAAGTAATTCGTCAATAGTTGTTTGGATCGTATGCTTGAATAATTCATCCTTTCTTA AATGTTGATGATC

TTTATACTCCATTTTCATTCTAACTTTAATATAAGGATCGTTATAATCTTGATGATC ATTAACTAGAGAT

TCAGGATGAAATATTTCATTAAATAATTTAATATCGTCATTTTTTCCATATTTTATA ATAATATTTGTAA

TTAATAATCTCGAAATTTCACCAATTTCATTATAAGGAATTTCTGATTCTTCAAATT TTAATGTATAATT

AATTTCTTTTAAATACTCATTATAGTATCGGTATTTATAATTAGATGTTAATGCAAG AGAAGTTACAAA

GTTAAGATTATTTTGATAACTTCCTACTAATCTAACTTCATTATAAAATACATTATC CTTTATAAGTTGA TTAATGATTTTATAATATCTTTGCATTAATACATTAAACTTATCGGTACTACAATTTTTT GGTTTAGTAA

TTGATTTAATTAATGATTGTTGGGTATTAATTAAATTTTCCATTTCGCTAAAGTCTG AAAGAACAAACT

TGTCAGGATCAATATTCTTTAATAAGTTATACGCATACATTAGAGTATTAACAATAT CGTAATCACTAC

AAGAATAAATATGGTTATTTCGCATAAAATTATACTTGAATTCATCACTAATTTCAG TAATTTGGTATG

GAATACCGTTATTAAGAAATGAAGTTATAATGTGTTTAACTTCTTGAACTGGTGAAC CGGAATTAAAT

AATTTTTCAATACATTTAATTCCGTGATAACTGAATTCTAAGTCATCTATATCATTA CAATAGTTCTTTT

TAGGAACAATTGAATTCTTCGTAATATTCTTATGAATATTACGAAATTCCCTATGAA GATCTTTAAAGT

TCTTTTTGAATGTATCATTATTACTAGTTTCTTTTAAATTAGCATAAATCTTAATTG TATTATTCATTATT

TATCAATCCTTTAATATATTTTTATTTTTCAATATTAACTTTAAATTCTATTCCTTG ATCTACCATATCAT

AATCAATATCAGCAACTCGACCAACGCTGATAATATATTGCTTGTACAATTCAGTAT CTTTAAGATTAT

GACCAAGATATGCAGTATCATATCTGTCACTTTCAATCTCTCCTGGACTATATTGAA CATTGGAGATCG

GGTTATCATTTAGATCTTTTAATACGTTATATTCTTTACGATCAGTATCAAAAAGCC TATTCATTGAACC

TTCAAAAGCTACTTCACCATCACTAAAATTTTCTATGATGAACTTACTGTTAAGAAA TATAGTGAGTCA

GTTGTTCTAACTTTATCATTAGGGTCAAAATTAGATGGTTTTGGGTCATTATCAAAC TTAACCCCTTTAT

TAGGAATAATATCCATACGAACTAGAGCTACTGTATAATCAGTGGCTTGTACTGGTC CGATTGTAAAC

ACATAATTTTCAGGAGAATTAACGATAACTGTCATAATAATTTTATAATCATTATCA TTAGTTACCCTA

TAGTCTCCTACCTCTGTAAGTTCATATTCTTCTTCTTTTTTGTTTTCATAAGGGGTT TAAGTTCTTGTATT

TTTGATTGAACTGAATCTTTGTTAACATGATTACTATCATTATTTAATACAAAATAA ATAACTACTGAT

AACCCTATTAATAATACTACAAATATTAATATTTTTTTCATTTGAAAGTTCCTCCGT TTTCTAGATTTTT

ATTGATTTTATATATTACTTTTAAACCTTTAGCAAATCTTTTAGATTTTACATCTTT CATACTAATTACA

TTACTTTTCTTAGCTACTTTTTTAATTTTCATAATTGATCCATCCTTTATATTTTAT TTAATCATTATTAT

AATATATTAATGAAAATTATATTATTACGCTAAAAAAAAAAAAATCCGTAATACTCA TAAAAGAGTAT

TACGGGAATATTTATATTATTTAAAATCTTTCACATATATGAAAACCATGATCAGTG GCTAATTTATAA

TCAAAGTTTAATCCTAGATTCATTAAATAAAACTTATCAGCTTCTTCCTTACTGAAT GTATTGATTAAT

GTTTCTAGTGACATATGACATTCTTTATCATAATCATAAGTTTCGCAAGAAGCATCA TGATATATCTCA

TCAAAGTAACCTTGATGAATAAGACTTTCAATATCATCACCGAAATTATTTGCGTCA CCACTATAATAT

ATTACTTTTTCATCAACCTTAATAATATATCCATACGTCATAATGCTCGGAGAATGT CCAACAGATACT

GCTTTTATTTGAACGTTAGAGTCAATATGATAAAATTCATATTCTTCAATAAATTGT ATTTTATAATCTA

CGTCTGCATGAACATCATTAATCTTTAATAAATTAACGATATTTTCACCATATGATA AAAATAGATTAA

CTTTTATATTATGAATATGTTTAAAGTATCTAATAAATGTTGGTAAGGAACCTATAC GGTCAGCGTGAG

TATGAGTAATAATTACATTAATGCTATCAAAATTCTTTATCATACTATCCATAAAAT AATCATCAATTA

ATATATCAAACACCATACTTCCACAATCAATAAGATAAAAATTGTTATTATTAATAA AGTATGCAGAC

GTATTTCCTAATTCTGTATTAAATTCATTTCCGGTTCCTATAAAATTTAGTAAATTA TTATACATTTTAT

ATACCGCCTTTATTTTTTTTTTTTATTATTTTTTCTAAAAAAATATTGGATATTGTC ATTTATTTGACAAT

ATCCAATAAAATAAGGAAAGTGTAAACTAGTTAGAATATTACACTTTTAGACGAAAG AGTAATATGGA

GATAACAACTAGTCGTACGGGATTAGAGATAGTTATATTTAGGCATAAGATTTACCT AAATATAATAT

ATTATTATCCAAAATATTAATTTTTTATTTTTACAGTTTACGCATATAAATCTTCAT TATAAGCGTATTG AATTCTTTATTGTATGAATTAATATCCGTAATATTATAATTATGACCAATAAGATTATCA TTGTTAATAT

TAGAATTATATACGCTAATTGCATTATTATATAATGCTTCTAATTCATCATAATTTT CTAATAAACTATA

CTTGTAATGTATATATACAAAGTTACTTATAATCATATCGATAAATTTTGAATCGAT ATTTGCAAAATA

TATTTTACTAGAATTAGATATAAGCGTTGGTATTGTAAAATTACCATGATACATTTC AGCATTAAAATA

ATTCTTCTTACATATTTCATAAATAACAGTATCGTCATTACTATTTAGATATTCATT ATACGTCATATTA

ATAAAATTTGCAAGATTGATTGGTTCTGTTTTGATATTTGAATAGACGATATTATTA TATGATTTATAA

TCGTGTAGCGTAGATCGTAATACATTTTCAGTAATTACACTATTACTACGAGAAAAA TTTTCTTTATAT

TGAAAGTACTTTTCAATATTAATTCTTAAGCAATTATTAACTTCTTCTAGATTAGAT CTAGATTCATTAT

TCGAAGTATCAATAATATCTTCCTTAATATAATTTCGCAGACTTTTCTCATCAGGAT TATTATGTAATAT

ATCTACTATAATAATCGCAGTTTTAATTAGTATATCCGTAGATTTTTTATCCGATCT ATTTCCAAAATTA

ATAATATTTCTTAAGAAATAAATTAATATCTTTGGATCATAGTTATACATATTATAT ATCATGCTGACA

AATATATTGTTAATTCCAATTCTTCCATTAAGAATATGTTCTATAAAATAATAATAC TTATTTGTAGAA

TCTTCATTATATTTATTATTAGCAATATACGCTGATTGGTTGGATACACGAATAAAG CTTGAATATAAT

GCAGAGATATAACTATTATTAAAATAAATAGTTGGAACGATATTACAAAAGAAATCA GCTAATTCTTT

AATATCTATAATATTTAGTATAGATTTTTTATAATACTTCATAAATTCTTTTGGCGT ATATTGGAGATTA

TCAATCTTGATCTTTTCAGTGTCAAACATAAGAGCGTGGGACTCATTTATAAATATA TTAAAATCATAT

ATATTTGAAGTGAATATATCTTTTAGGAAACTATATTTATCTTTGATTAATGAATAC ATTGTATTTCTAA

TCATATTTTGAAAATATATAATTCGTAGATTATTACTTTTTTTAGTATTGTCAGAAT CGACTAATGATTT

AATTTCTTTATAATATTTTGATAGATTAGATTTGGAAAAAGTTTCGTTAAATTCTTT ACAATCATCTAAA

AATTTGTTATATACTTTATCGACAAGATCACTATTACTGATTTCATGAGTATCATAT TTATTTTTTATTT

TATCGATAGAATTTTCGTCATAATAAATTCTATCGATAAAACTACTAATTATCGGCA TGTTGATGTATC

ACTTCTTTCCATTGATATAGTGCATAATGTCAATATGTAACAAAATGCTCTTACTCT GATCTCTACTGG

CATTACAATAATCAAATTCATGCTGATAATGATCCAATAACATTAATGCATAGTTAT ATTGATTTTGGA

TGATGCTTGAAATATTATTACTTAATTTATATTCTAAATATTCAATAATATTTAGAA CTTCATTGTCAAT

AGGATTAATTTTTTCATAATTATTTAATAAGTAATGATATACATTTTTATAAATTTC GACAGAATCATT

ACTTATTTGAATGTCATTATTTATTGAAAAACAAAATAACGAATTAAAATCATTAGG ATCAATTAATA

_{GTTTTTCTAAAATAATCTTAGTCTTTTCACTTTCTTTATATTCAATCCATCTTAC AGGGATATATTCAGC}

TCTCTGCATGCTAATGAGAGATTTAAATAACTTAATTGAATTTTTCTTTTCTTGCAA ACTATATTTACTA

AAAATATAATTTATCATATTTTCTACAAAAAGATTAATTCTACCAATAGTATGGTTT ACTGTAGCCATG

TTTGTTCCTTCAATAATATGATCTTTACTGCTAACATTAATAATAAACATTCTTTAT CATCCTTCACTGT

TTTATTTTATTCACATTATTATAATATATACTTATCTTATTAGTAAAAAAAGAACTA TCACATTTTATTA

TGTAATAGTTCTTCTATGGATTAATTGATGAATTAATTTCTGTACTATTATTTATTC GGTTAATTTTATC

TTCTAAAGATATCAACCTAATAACATTTTTTTTTTTATTTGTCATATAAAATAAATC ACTCTTTTATTCA

TAATTATTCTATTATCATATGCACTTCTTTATAAGATATATTTATAGAAACTGTATA TTAATAACAGTTT

CTATATTAATGATAGTTTAACTTTATCAAAGATGTTTCTATGATTAAGAGAATTCTT AATAAGGTCATT

AATAGTTATATTTATGTGGTAAGGTTTTACATTATCTTCTGCATTATAAATCTGTAA ATTTATATTGTAT

CCATTTACTATAAATTTATAATATACCGAAACATATTCTCTTGTTACTGGTTGCTTA AAACGGTCAGAC GTAAAAGTATAATTAAATGTATAAGAATCAATATAACCATTATTAGTTGATAAATCACTG ATATTATA

AGTATATTCATCGATGTCTGATGGGTCAAGATCTGTATTATTTCTAATAAATTCATA GATCATACTTTTT

AGGATTTCCGATAGATATGTGATAGTTAATATTGAAGAACTAAATCTTTTACTATTA AATTTTTCTTTTA

TATTGTAAGTATTATCATTATATTCAATATCTTTTGATGGAATATTATAATTAGATG TAAACATTTCGTT

AAATGTTTTTCGTTCTTCAGAAGTTAATTCATTTAATGTTTTAATTAATTCTTTGTC ATTATATAATAAA

AATGAATTAATTATATGGTACGTAATATTCCCATTAACATGTAAAGGTTTACTTAAA AATCCTAGAGAT

TTTACCATTAGATAATTTCCTTTCTTTTTTTTTTTAATATTAATTTTAGATATTATA CATTTTAATTCTAT

CATAATATTTGATATTCTACTTCTTTCCTTTATACTTATATGGATTCAAGAATCATT TTATCATATATTTT

CATATGTTTCCCACAATCAAATAATAGATCAATCATATTAATATTTTTGTTAAAAAT TTTATCATTAAT

GAAAAAATCAATATCTAATTCATTGCTATCTTTATCCATACTAAATTTAATTTTGTC AGAAATAAATGT

AAATTTAGTATAAGGATGATAATTCTCCATAAATTTATATTCGGGTATATCTTGAAT TCTTATTAGGGC

AGAGACTTCAAATTTTAATATTAATGCTAAAAATTTCTTAAAGAAATTAGATTCTAG TATATTCCAGAC

GCCAAAAATATCATTCTCTCGATATTTACTAAAACTAAATATACGCTCTAAGTTATC AATCATTTCCAT

ATTATTTAGTTTTGTCAATTTTTCTTCTAAGTCATCATAAATCTCAAATATTTGTAC AATATCATTTTGA

TTTGTTTCGAAAATATACATAGATACTATTTCCTCATACACGCTATTATCTATGTAT GGAATAAATGAA

TTTTTAGCTGAATCTTTAATCTGTTTTATATTTTTCATGTATACCATTCCTTTCATT CTTTAATTTCAAGA

ATATTATGTGGGAAGATATCAATTAAAGATACCTTCCCACATAATATATGTAACGAT TGTTTAGTACAA

CATATCACTATATTTATTCATAATATTCTTTGTAAATATATAAAGGACTTGTTCAAA TTCAATATCGGTC

AAACATAATTTACCGTAGGCTTGACGATTACAAAATGATGAGATAGTTGATAATGAA TTACCATGAAA

AACCATTCTTTCAAGCACTCTGTTTTGATTGTCATTAAGCTTATCATATTTTTCTTG GGAAGTGATCATT

TTATGAGTCATACTTAATAGATCGCCTTCTAAAGTATTAGGGAAAACATAATTACCT TCAGAATTTAAA

TAAAAATGGTTAAATCGATTTAATATTTCTTTTTGATAATTTTCTTTTGTTTTATTC AACACTATTAAAA

CCCCCATAACCAATTAGAATTATTTATATACTATATATTTATTTATTAGTATATCAA TTTATTTTGAGTA

ATATGGAAAAAATTATTTTAAAATCCCTAAATAAACATATAAGTTTACTTAAGGATC ATAGATATTTTT

AATTCTTTATTTTATTAAATACTTTTTAATTTATTAATATCAATTAATTTCTTTTTC ATACTTTCAGGTAA

TATTTCATCATGATACTTTAATATTAAAGGAATATTTAATTTATCAATATACGTATC AATAAATTCTAG

TGATATATCTTGACATTTGCTAATAATATCCCAATTAACTTTATCTTGAAACTCAAT AATAAAGTCTTCT

GATAATGTCTGGTACCAACTAATAAAGTACCAATCTAAAGAATCTTTGAATCTACGA ATAAAATCTTC

TGATAATTTCTGTTGTGAACTAATATTATACCAATCTAATTCATCTTGGAACCTTTC AATAAATTCTTCT

GATAATGTCTCGATACCTACTGATGCTAAACCAGTTTAATTTATCTTGAAACTTTTC AATGAATTCTTCT

GATAACTCTTGATGTATGCTGATGCTAGACCAGTTTAATTTATCTTGAAACTTTTCG ATAAATTCTTCG

GATAATTTCTGTTGTGAACTAATATTATACCAATCTATTTTATCCTGAAACTTCTCA ATGAATTCTTCTG

ATAATGTCTGATTCCTACTGACATGATTCCTATTAATGGTTATTTTTCCATAAATAA GTATACCACCTTT

TTGCTATATACTTTTTAATTTAATAATTTCTTTATGTTTATTAATAAATTATCGTGA TACATTTTGAATC

GATTCAATATAATGCCAATTTACTTTATTCTGAAACTTCTCAATAAACTTTTCCGAA AATTTCTGTTCTC

TACTGATATAACTCCAATTTACTTTATCTTGAAATTTTTCGATGAATTCTTCTGATA GTTTTTGGTCAGA

CGATATATAGTCCCAATCTACTTTATCTTGAAACTCTTCGATGAATTTTTCGGATAA TCTCTGATATATA CTAATATGCTTCCAATTAACTTTATCTTGAAATTTTCTAATTAATTCTTCTGATAATTTC TGGCATAAAC

CAATATAATGCCAATCTACTTTATCCTGAAACTTCTCAATGAATTCTTCGGATAATT TATAATATTCAG

AGATACTACACCAATTAACTTTATCCTGAAACTTTTCAATAAACTGCTCAGATAATT TCTGATATGAAC

TAATATTGTACCAAACTACTTTATCCTGATATTTAGAAATAAAATTTTCTGATAAGT TCTTTTGATCCCT

ACTAATATTGTACCAAACTACTTTATCTTGAAACTCTTCAATAAACTGCTCAGATAA TGTCTGATACCA

ACTAATATTGTACCAATTAACTTTATTCTGATATTTAGAAATAAAATTTTCTGATAA GTTCTTTTGATCC

TTACTAATATAATACCAATCTACTTTATCCTGAAACTTTTCAATGAATTCTTCTGAT AATTTTTGATGTG

AGCTAATATATTTCCAATCTACTTTATCCTGAAACTTTTCAATGAATTCTTCGGATA ATTTTTTCTTCCA

ACTAATCTCAGTCCAATCTACTTTTACTGAATCATCAACGATTATTTTATCCATAGA TAATATTACATCC

TTTCTTTTTTCACTATATACTTTTTAATTTATCAATAGCAATCAATTTATCCATTGT TTCTTCAGATAGTG

TATCTTCGTATCTATATATTAGATATTTAACGTATAATTTATGCATATATCTAATAA TGAATTCTTCCGA

TAATTCTTGATGCATACTAATAGCTTTCCAATTAATTTTATCCTGAAACTCTTCAAT AAAATTTTCAGAC

AATGTCTGATATTTGCTAATTTCATTCCAATCTACCATATCCTGACAGTTACGAATA AAATCTTCTGAT

AAGTCTCGAACTGACGAAGAAGCATGCCGCCAATTAACATTTTCTGGAAATTTTAGA ATAAGGTCATT

AGATACATTTCTATTTAAGCAAAAATAATCCCAACATATCTTATCTTGAAATTTGGC AATAAATGATTC

ACTATTTAATTTCTGATGCATACTGATTTCATTCCAATTAACTCTATCCTGAAACTC TTCAATGAATTCT

TCTGATAGTTTTTGGTCAGACGATATATATTGCCAATTAACTTTATCTTGATATTTA CGAATAAATTTTT

CCGATAATTTTTGGTATTGACTTATAATATCCCAGTTTAATTTATCTTGATATTTAA TGATAAACTTTTC

AGGCAATTCTTCATTATATGCAATATATTCCCAGTTAGGTTCAACAGTAAAATTATA TTTTTCATTATA

CTTCATAGGAAACCCTCTTTCTTTTAAGCTATTATATATTCTTCATTATAGTAATAT TAGTCAGCTTATC

TATAGTTTTCTGAGATAACGAGTTTTTATGAATTTCAAGTACGAATTCAATATCCAA GCAATGAATATT

CCTAAGAATAAAATCATCTGACAATTTCTGGTATTGGATAATAAAATCCCAGTACAC TTTATTTCCAAA

ATTTTCAATGAATTCTTCTGATAATTTTTGATATTGGGAAATATTATACCAATTAAC TCTATCTTGAAAC

TCAATAATAAAGTCTTCTGATAATGTCTGGTACCAACTAATTTCATTCCAATCTACT ATATTCTGACAA

TTACGAATAAGATCTTCTGATAGCTTTTGGTTTATACTGATGTAGTACCAATTAACT CTATCCTGAAAC

TTAATAATAAATGAATCAGATAATTCCTGAAATATACTAATATATTTCCAATTAACC ATGTCTTGATAT

TTATGGATAAGTTTTTCTGATAATTTCTGTTTTATACTAATAAAGTCCCAATCTAAT TTGTCTTGAAAAG

TATCAATAAATTTTTCATTCAACATTATGTTCTTAGATATGTATGTCCAATCAATTT TATCATCATTTAT

GTTAATATCATTAGTTTTAATGTACTCGTTAATATTCATAAATTATAACCACCTTAT TTTTCTTCTATAT

GTATAATATATAATTTTAATTTATGTTAGATGTATAAAAAAAAGGAAATGCGTATTT AATAAATGTATA

ATTCCTATATAATTATTATATTATATAAGAATTATACATTTAGTAGTTATATATGTC TTAATGCATCAAT

TTCCTCTAATCTATTTATGAATTCTTTAGATAATGATTCTGAATTATTATTTATTAT TGAACTAATCGAT

ACTTTATCAATATGATTATTAATAAATTCTTCTGATAATTGTTGCTCTCCACTAATA ACGTTCCAATTAA

CTTTATCTTGAAATTTATCAATAAAAGATTCCGATAATGTCTGATATCTACTAATAT AGTACCAACTAA

GTTTATCTTGAAATTTCTCAATGAATTCTTCTGATAATTGTTGATCTGTACTAATAA CATCCCAGTCTAC

TTTATCCTGATATTTACGAATAAATTTTTCCGATAATATTTGGTATTGACTTATAAT ATCCCAGTTTAAT

TTATCTTGAAATTTCTCAATGAATTCTTCTGATAATTTCTGTTGTGAACTAATAATG TACCAATCTATTT TATCTTGGAACCTTTCAATGAATTCTTCTGATAATTTTCGATACCTGCTGATGCTAGACC AGTTTAATTT

ATCTTGGAACTTCTCAATGAATTCCTCAGATAATTCTTGATGTATACTGATGCTAGA CCAGTTTAATTT

ATCTTGGAACTTCTCAATGAATTCCTCAGATAACTTTTGATTTCTACTAATATCATA CCAATCTAATTTA

TTTTTCAGATTATTAATAAAATCTTTATCATCTAAGTTTTTATTTTTCATAAGTATA TCAATCCTTTATAC

TAATATTTAAACATGTCTTAATTTATTAATTTCTTTTAATTTATCTACAAATTCTTT AGATAATGATTTT

GAATTGTATTGTAGTAATGCTTCAAGATTTAATTTATTTAGATATTTATGGATAAAT GTCTTAGATAAC

TTTTGGTTTCTACTAATAGACTCCCAGTTTAATTTATCCTGAAACTTAATGATAAAT TCTTCTGATAATA

CTTGACATGCACCAATATATTGCCAGTTAATCCTATTTTGGAACTTCTCAATGAATT CTTCTGATAATTG

TTGCTCTTCACTAATAACGTCCCAATCAATTTTATCTTGAAATTTATCAATAAAAGT TTCAGATAATTTT

TGGAACCGACTAATTAAGTACCAATTTACATTACTCTGAAACTCTTCAATAAATTCT TCTGATAACTTT

TGATGTTCACAGATTAAAAGCCAATTTACATTACTCTGAAATTTACGAATAGATTCT TCAGATAATTTT

TGAGATCGACTAACTTGACTCCAGATTAATTTATTTTGAAACTTACTAATAAATTCT CCTGACAGTTTTT

CACATTGAGATATATAATACCAATCCAATTTATCTTGGAACTTCTCGATAAACTCTT CAGATAATTTTT

GATATGTTACAATAAAATCCCAGTCAACAGTATTCTGAAACTTATCAATAAAAGTTT CAGATAATTTTT

GATATATGCTGATATAAAACCAATTAACTTTATCTTGGAATTCTTCGATGAATTCTT CTGATAGTTTTTG

GTATATACTGATATTTGACCATACTACTTTATCTTGGAATTTTCTAATAAAGTCTTC AGATAATGTACGT

TTTTCACATAATAACCCCCAATTAATCTTTTCGGGGAATTCACTTATAAACTCTTCG GTTAGGTTTTTAT

TCCACATAAAAGTATACCATTCCTTCTCTATAAAGATATTTAGATACTTTTTATTTT ATTAATTTGAATT

AGTTTATTTAACAATTGAGGTGATAATAATTCTGAATTGTACTGTATTAGGTGTTCA ATATTTAATTTAT

TTAAATGATTATAGATAAACTTCTCAGATAATTTTTGATATCTGCTAATATAATCCC AATTAACTTTATC

TTGGAACTTAATGATAAAGTTTTCTGATAGTTTTTGATATTGACTTGTAGCATCCCA ATCAAGCTTATTC

TGAAAATCAGTGATGAATTCTTCCGATAATATTTGATATTGACTAACATCCTCCCAA TCATTTATCATA

TCTTGAAACTTAATGATAAAGTTTTCTGACAATTTATGATAAATTACGACTAAGTAC CAATTAAGTTTA

TATCTAAATTTTTCGATGAATTCTTCTGATAATTTTTGATCTCCACTAATAGTATGC CAATCAATATTGT

CCTGAAGTTCTTCGATGAATTCTTCGGATAATTCTTGATATTCACTAATATTAATCC AATTAACTTTATC

TTTAAATCTAGCAATAAAGTCTTCTGATAATTTCTGATATTGGCTTATATTATACCA ATCTACATTGTTT

TGAAATTCTTCAATAAAGTCTTCCGATAATTCTTGATATCGACTAATAATATCCCAT TTTAAATTATTCT

GGAATTTACGGATAAAGTCTTCCGATAATTCTTGATATCGACTAATAATATCCCATT TTACATTATTCT

GGAATTTGCGAATAAAGTCTTCTGATAATTTCTGATATTCACTAATATTAGTCCAGT CAACTTTATCTT

GAAATTCGATAATAAATTTCTTTGATAGTTTTTGATGTTTAGAAATACTGTGCCAAT TTACTTTATCTTG

AAACTCACGGATAAATTTTTCCGATAATTTTTGATATTTACTAACGTCTGTCCATCT AATAATATCTTGA

TATTCACGGATAAAATCTTCAGGCAACTTAACACATGATACCGTAGTATACCAATCA TAACCAAACCT

TTCAAGTGTTACGTGACTTATATTATTATTGACTGTTTCCATAGTACTTAATTCCTC CTATAATATCATT

TTTAATCTTATTAAGAAATTAGACCAAGTTAATATCTAATTTTTTGAAGTATAAATT AATAAATTCCTC

TAATAGTTTTATGAAAATAAAATATATTCTCAGTATATTTATTATGTGAAAAATCAG CACATATTCATC

ATATCATTAATAATACGCTTTCTCTCTTTTTTTGATACAATGTAATACGTGTTATCA ATATAATTAAATT

CTTTAATAAAATCTTCCGATAATATTTGATATCGACTTATAATATCCCAGTTTACAT TATCTTGAAACTC ATGGATAAAATCTTCAGATAATTTTTGGTACATACTAATATAATCCCAATCTACTTTATC CTGAAATTC

TCTAATAGAGTCTTCTGACAATCTTTGATATATGCTAATATTTTCCCAGTCTACATT ATCTTGGAATTCT

TCAGATAATTTTTGATACCTTGAAGATTGATACAAATTTGTAATTTTATTATATTCA ATATTAATATCAT

TGTTATATTTGATATCGCTATCATGATTATCATTATTATTTAGTGATAACACATGAT TTTTATCTTTTAT

AACATTATCATATTTTGGAATATACAATATTAAGGGATCATTATTACTATTATCATC TAGATTTTTTGA

AATTTCAATATTAGCGGAATTAGATTTAATTTTATCAATATATACTTTATTTCTAAA TTCTATAATAAAC

TTTTTGGATAGTTTTTGCGAATTGGATAATTTTTGTGAAAATATAAGATGTTCCCAA TATAATTCCGATT

CATATTTTCTTATAAATTCTTCAGACAATCCTCTGGTTCTATCAATCATGTTCCAAT TTAAATTATATGG

ATTAAGTTCGACAATCTCTTCGACAGTATAATAACAATTAATATCCATAATAATCCC TCATTTCATTTA

TTATTTTAATATATGATGCATTTATACATTATAATTATAATATATATTTATCCTATA AGTTATAAAAAAA

AAAATCAAACGTGATATATAATGATTATCACGTTTGATATGTAATTATTTTTTAAGA ATGTTTAATAGT

CTTAGAGAATATTCTAAATATTTAGATTGATTTTTTACATTGTAAGTTATTAATAAT AATAATGAAGAG

AGAAGGAACAGATCTCCTGATTTACAATAATCTTTTTGATATTTTCCATACATTACA TTACATTTCAAT

AGCGTTAATAAGATCTAATTCTGCAATAAGCTGACTTACTCGGTGATCTGATAGATT TTTCCTATTTTG

AATTTCTTGTTCTTTTGCTTCATCTAAAATATTATTTAATGCTAACATAATTCTATC TAATAGAACCATC

GATTCCTTATAAACTTTTACAGAATTTTCACGATTTTTAAGAATATTTATTAAATTA CTGAGACTTAATT

CATACTGTCTTATTTCTTCGCCATGATTATTGATTTTTGTAAGTTCAAGTTTTGCAA TAAATAACCGAAT

AATATCAATATTCCTATCCCTATTATCCATTAATAGAATTATATTTTTTAGATTTTC GCAAATACCATCA

ACTGATACCATTATATTTCACCTTCTATTCTACTTTTAGTAAACATATTAAGTGCTT CTAATTCATTATT

GATCATTTCCAAATTTACTTCTTGTAAATTCTTTTCTTTCATTAATTTAATTTGTTC TTGATTTTCTTTTTC

TTTTTCTACAGATTTAGTAATTACTTCTTCAATCTTAACAAGTAATGAATTTACTGT TGTATATACTTCA

TCTGAAAATATTGCACTATTTTCATTTAAGTGTCCAATAATTATATCATTTATGCTT GATAAACTTAATC

TAATTTTATCATGTGTATGGATATTGTATTTTAATAGATTAGATACTTTTTTGTTTT TCATTAATGAATT

AATAGTTCTTCTTAATCGATTATTATAGTTTTTATCTTTAAAGTATTGAATATACTC GATATTTTTATTA

ATGAATTTAATAAAATCAATAGCGTCCATATCCGGAATATATTTTTCAGTTGAATAA ATTATTGCATTA

TCATTATTATTTTTATATCTTAGTGAGTTTGATCTAGTTAAGTGCCTATTTATATAT CTAAGATCATTTG

TAGCTTGATCTATTTCACTGAAATTAACGGAATCATCTCTTACAATATCTTTATAGT CACGAAGTATTA

AATATCCTGAACTAATAATACCTTTAGTTAAATGATTATTTTTAATGCGCATATAAG TCTCAATATTAT

TTTTAATAATATTGAGGCAACTTTGGATATTTAATGAATCAATATTATTTAAACTAA TATATTCGATTTC

ATTAAACAATTTAGACAATTCTTTACTTCTAGATAAATTTTCTGAAAGTAAAAATTT ATCTAAAAGATC

ATCATTCTTATTATTTTTTATTTTAATAAATTTAAACATTCGATCACCATCCAGTTA ATTATTATAATTC

TTTCTAATCTTTGTTATATAAATTTATTATCATTTCGAAAATTCAGATATTTCTCAA TTCTCTGATCTTA

ACTAATTTACGCTTTATTTTATTAGATATTAGTTTATCATGTGATATCAATAGATCA ATATCTAATTTCT

TGAAGAATATATTAATGAATTCTTCTGATAAATTTTCACAATATATAGATTTGCCCT TCCAGTTGATTG

TACTATTATTTTCAATAGATAAGTATTAATCTTCAGTTAGATCAATAATATCTTCAA GATGTGAACCAA

AAGTAGAATAGTCTATTAACCATATTTCTTTTAATGGGTCTTCTTCAAGAAAGATTG CAATATCTTTTG

CATGTTTCTTAATTTTATCCACAATATAATTATACGTTCGATCAGCACCACTAGGAT TCTTAATGGATCT TAGAAAAACGTCATCATAAGATTCAGTTTCAATAATATGATATCCTTCATAAGTTTTATT TCCTTTTTGT

AACGTCACCGATCTTAATACACTTTTTCGAGTTTCTTTAATGCCAATTAGGTCAGCT AAATTAATTACTT

_{CTTTTTTATTCAGATCAATTCCATTTTCTAGTACAAAAGGAACTGGTTGTAGGTT CTCGTATTCCTCATC}

ATCAATATCACTTAGTGAATTAATATATTCTAAAGCATCATTATATGATTTAAATAC CTTATGTTTATTC

TTTTCCGTATTAGTAATTTTATATTTGATTGTCATAGACCATCAATCCCTTCATTTA GTTAATTTTTATTT

TTAAATTCTAGTTTAATATTATTACTCTGAACCTTACGTAAATACGATAATATCGAA TTCACCTTTACTT

TCCATACATCATTCACAACAGAAAGTATTTGCTTCATCCGATAATATATCTGATTAT TATTATCGATGG

CAAGAATTATACTCATATGCTGAGCCTGAATTACCTTATCAATCGTAATAATATCGT ACAAGTTTCTTT

CATTTCTACTTTTAATTAATTCTTCGCCATCATTATACTTAATTGGTCTTATCTTCA TAAGTTCACTAAC

AGATTTAATAATTTCAGACGTATTTATACATTCCATATTATCATTCAAAATTTCTTT TAAATATTGAATA

TTATTATCTGTCTGCTTAATATTATTTAATAAGTATACTTCATATTCTGCGATAATA AATAAAATATCCT

TATATTTTTCACGAACAGTACTAATCTCACGATTATTTCGAATATTATAGTCACTAT CAATATTGGACA

TCATTCTCATAATAGTATCAGATTTTTCTTCAATATAATTAATATACGTTTCATTAT ATGCGTAACGTAT

AATATCCTTTGATACTTGGTTATTTATTGACTGAAGTTTATGCGATATTTCAAAGAT CTCTATTTTACGA

TTAACTACGTCATAATATATTTCTTGAGCTTCTTTCTTTTTATCCAGTGATAAGCTT GAATACGTAGGAA

CTTTATCATACATAGCAGGATGTATATACAATATATTATCTCCTTTCATTATTATTA TTATTGTTGATTT

ATTAAATATATATTAATAATATATATGCATTTTTATAATAAAGTTTAATATTATTCC CTAATACAAGAA

TTTACATTTATCTTGTATTAGGGAACAAATTTATTTATTTTGATCTATATTAATAAA ATATAATACCCAA

AAAGACCATATTAACCCAAAGATGATTATTAAAAATCTAAAAATTAATGAATCTATA AGCAATCCTAA

TATAATTAATATTAGTGACATTATGGTTAAAATCATTAATACTATTTCTTTATGATC TTTTAATAAGTTA

AATATTTTTTTCATAATAAAACCCCCATTATAATATAATAATTAAATGTATAAAAAA ATTAAATCATAA

AATTTAATTTATGTAACTTGTTAGGGGAGAACGAGTTACGTCGTATCTCTTGCGTTA TCAACAATATTT

ATAGTTGTTCATAAATATTATGACTTTTGTATTTTGCATTTTTGTTATTTCCAATAA TTGTTATATAGTTT

TGGTATATTAATCTATATATTATTTCATCATTACAATAGAACCAACCTTATAGTAAA AATTATATATAA

AGAATAAAAAATCTATATAATTTACCTTCGGTATAAGGATTGTTACATAGAAGGAAA GATCTACATAT

TTTTATTAAAAAGCATATATGGATTTATAGTTAAGTCAGAACCAACCCTATAGTAAA AATTATATTAAT

AATTATATTTTATTATGAGTTTAATGCTTCGTTGTAAGAATCTTTACATGCACGGAT AAATTATAGTTA

ATTGTTATGTATAATATATCCAAGCATGTAAGGTTTCTTAGATTATTTTTATTTTTT ATTATTTTAATAA

CTAATAAAGATATTAAACTTAATTTATTTCGTTATATATAATATTAAAGTAATTATT TATCTATATGATT

TACTTCTATAACTTTAATTTCTAGTTCTGAAACTTCTTCGTGTTTTCTGAATACTGA TGCAGTATTTCTT

GTAACGTATATTTTATGTTTTCCGGGAATCCATTCAATATTGATTTTAAGATTATCC TGAATCATTTTAA

TGAGCGTTAGTCTACTAGCTTTATTTACTAATTCGCCCCAAAGGTAATATTCATTAT AACCATTATTCCT

AAGAATGTCTAATTCTTTTTTTGATAATTTGTATTTTGTTTCATAAGTTATTTCCAT GATTTATTAATTAT

CCACCTTTATTTATTATTTTTAAAGATCAATAATGTTATCTAGATGTAAAGATTCTT TATCTAATGAATT

ATTATCGATAATATAGTTAATTCTTGATTTAACGATGACGTCAGTTATTCTCTTAAT TTCTTTAATGCAG

GCACTATATAATTCATTCTTGTCTATTTTTGTTATCTTTAAGGTAAGATCTTCAAGC TTTTCGTAATCAA

TTGGTTGTTCACGTCCATACATAATCCAACTTGTATATCCACTACTTACTTTTTTTC TTTTCAGTATTTCA GTGTTATAGTAATTTGTGATGGTAGAAAAATATTTTTGCCTTTTTCTTTTAATACTTTTA AAGTATATTT

TGTTGTCTGAATGAACGCAGAATTTTAAGTTAAATGAATTGTTAATAAGAACTTCAA AATCTAAATCAT

CTAATACCATTTAATAATTCATTCCTTTCATTTATTTAATTGTTTTATGCTCCAAAG AATATCTGATTTT

AAGTCTTCTAGGAATTTTACCGTACTAATAATAGTGTTTTCGTGTAAGTAATCTTTT TCTAGTATCATTC

TTTCTTTATATATTTCAATTAATTGGAATAATCTTTCTTTATGTTTAGAAAGATAAG CATAACCTAAGAT

TTCTGCTGAGAAGACGATATATTCATCATTCAAATTATCAATTCTTTTTTGAGACAG ATTATTATCATTT

TTATAAGACGTCATAATTTCAGAGATTAGATCATAATATAAGTTACTTAATACTTTT ATTGTCTTTTCTA

TTAACCTATTAAATTTTTCTGCTTTTTCTTCTTGAATTAAAATAATCGTATCATTAA TAGCATTATTATA

GGAATATTCTTCATTGCTGTAAAGATATGTTTTCTTTTTATCTTCTAATTTCTTTTC TATTTCCTTAATAG

TATTGATTTGTATTTTTATACTATTAATTGAATCATCATCGCTGATTGGGATATTGT CCATCTTTTTAAT

AAGAGACGTATCCGTTTTTAAATAATTATCTTTAGTATCAATCGCTACCTTATTACC ATCTAATTCTTTT

ATTATACCTTCTTTTGTAACGCCATTATGCATTACTTTTACACGTTCACCTATCTCA AACTTTTCCATCA

TTTTCACCCCACATCTATTTCTTCAATAGGAACTGCAAATTGCCAATAACGCTCATC TGATGACTTTATT

TGTTCTTTTGTTAACTTAGTAGTAAACCCAGATGATATTTGAAAAGGAATAAGTTGT CTTTTTGCAAAC

ATACCACTTACGCCTGTAGAAGGGTTTATCGCTAGATATAAATAATCATTAACTTTT TTAGAAACATTT

TTATCCCATTTCAGTTCATTATTTTCAATAAATTGAACTTGTTCGTCTATTTCGAAT TTCATAAATATGA

TTTCTTAAATTAATTATTTTTTCACTAATAGTCTTATCAATATTAATAATATTATTT TTCTTCTTTTTAAA

AAACATATTCACCATTCCTTTAACTTATTCATTCTTTAATTTTTTGTTAATTGAATC TTTACTAATATTTC

GAATAATTTCTAGTTCATCAGATAATATATCATCAATAGTATTATTCTTAGATATTT TAATATTTTTATC

CATATCTTTATATACTTCGAATATTTTAGAGAAATCGTTATAGATAGTAATTAATAT TTCTTTAATTTTT

TCATACATAGATTTGGTAATTATTCCTTCAGTCTCTTGACCAATATTAATAATAATA TTGTAAATATTAT

TAATTGTATCAATATACTGGGAGAGTTCTTCAGTGAATTCATTTTTTTGTTGATTTA ATATTGACATATT

ATCAGACTTAATAAGTATTTTATCGATTATATCTAAAAGTTTAACATGATAATTAGT TTTACCATTTAC

ACCCATTACATAATCATATAACGGTTTAGATCTATTAATATTTTCGTCAATTTCATT ATCTGATAATCTA

TCGTAGTTATACAAACGATATCCACCTTTTTTTAATATATTATACCTTTTTACATAT GGATGAGATTTAT

TAATATTAATTTTGAAATCATATACTATATTTTTAATACTAAATTTATCATACATAA TCTGATACTCATA

ACTAATAGTAGAACGTTCTCGGATGTAGTATTTTTTATCCATAAAGATATTATCAAA GTATTCATAATA

TTCTTGGGGTGAAGGTAGTTTGTCTGTAGTAATTTGAATTATTGATACCTTATGAAT TGATTCAACTAA

GGTATTAATAATTTGCTTTCTTAATTTGATTAATTCATTATCGATAGTTATAACCGA TTCTGTATCTGAT

AATTCATCAGTAATCACATCTTCAGGTTCTTCATTATTTATTTTTTTATGTGATTTT CTTTTAAAAAACA

TGTTCATCATTCCTTTTCTATAATATTTATTTAATTTATTAATAACAATAAAGTTTT TTCTTTAGTAACTA

TCTTTTTAAAATATTAGTTTATCATTACAGGAATAACTAATTTAATAGTTATTCCTG TAATAATTTTTCT

TTTAATTTATATCTTCGTATATAATAAGATACTGAATCATTTTTCATATGAACATTG GTTGAGATTTCAG

AGATAGTTGCTTTTGGATTCTTTTTTAGATATTCTAAGATACTATTGATTCTTGAAT TAGTAGAATCATC

ATCACTATTTCGAATACCTTTAATTTTTCGATTATATTTAATATTATTCTTTTTAAT ATATGACTGAATT

GTGTGATATTCTACATTAAAATGTTTTGCAATTTCTGTCATTGTTAAATTCGGATTT TCTTCAATAAATT

TGGATAATCCTTCAATTTTTACTTTTATTTTCGGACCAATACCTTTTTTACTTACAT ATGGTAGATCATA _{TTTTTTAATCTTTTCCCTTAATGTATTTGGAACATAGTAAATTTTTTCAGATAAT TCATTAACTGATAAT}

TCGGGATTTTTCATAATGATATTTCTTAGATATTCTTTTTCCTGAATTTGATCTTTA GAAAGTTTTTTGAT

CATTATATATACCTTCTTTGTTATATAATTTTTCTACTTTTATTAATTCGTCTAATA TAATTATTAATTGT

AGATACATTTGCATTAAAATGTTTAGCAATCTTGCTTGCTGTAGCTTCAGGATATTT TATCATAAAATT

AATAATTTCATTATCATCAAACATTTTATCCACCCTTTTACTTTTATAGGGGATATT GTTTCTTTTAATT

GTATTACCAATAAATGACTTTGATACATAAAAGTGTTTTGCAATTTTATCTAATGTT AAGTCAGGATTA

TCGCTAATATATTTAGAAAGGTCGTTAATATTGATAATATCTTCATAAATAACAGTA TCGTTATCATAA

TTATATTGCATATTATATTCCTTAATATATTTACGGATGGTTGGTGCAGAGTAACCA GTTCCTGATGCA

ATTTTCTTTATTGAATGAGTAGGGTTACTATTAATATATTCTTTAATAATATTAGGA TCTACTTTTTTCA

AAACTTTATTCACAACACTTTCATTTTATTTAGTATTCTTCTTTTCCTTAGCAAAGT ATGCAATTAGTAT

GTATATTATCATAGATATTAATGTTATTATATCTAAGACATATTCATTAATAGTTAT TGCATTATGGTGT

ATTCCATATAAGAATGTATATATTGTGGTATACACATTATTGAATATAAGGATTATT AGAGGTATATAC

CTCATTTTATAACGAAGTTTATATAGGGATACTTCATGACTACTATATAGTAATAAT CCAATAAGAAGA

TTAGCCGTTAATGCTAATGTATATGTTATTTTTTCAGACAATACTTCATTAGTAGTA AATAAATTTATTG

TAAGAAATATAATCATAAAGAATATAAATAAGCTTGTTATTAGTCTAGTTCGAATAT CAATTTTTTCAT

TATTAATACACGATATATAGACTAATAAAAAGATTACAAGATTTGTTAGTAACATAT AATAATAATCC

TACTTTCCATATACTTATAAGAAGAATCCCCATTAATAAAGGATTCTTCTTATAATC TAAATTTATTTTA

CATATACTTTATATGATTCAAGTAATTTATTTTTCTTTGATAGTTTAGTATTGATAA GTTTTCTGAAAAA

TAACTTTGTGTTGAAAGAGATTTGCGTTAATTCTGTTTTATCTTCACCAAAATTAGT GCTTTCGTAAGAT

GCGGCTGATTTAATTACACCCCTATTAATAAGATTTTCTTCAGAATATGTAGATAAT TTACCGTTATTA

CCAATCATAACTACAAATTCAATTGATTCATCAATATTGCCGATAAAATGTTTTAAA TTTTCAATAAAA

ATTCTTTTTTCATTAAATGTTCTAAGTCTACGTTTTCTATCAATTTCAATAATAAAT GCTTTCGGTTTCTT

TTTGATATTATTAAATAGTTTAATAATATCTTCTTTAATAAATTTTAGATTAGTATC ACTGGTGATATAG

TATTGTAAGTAATATTCTTCAGATTTTAAATTATTTACTTTTTTGGTAATATCATAA AAAGTAGTAGTTT

CAATTAATGGAATAATATAGTTACTTTTAATACTCGTGATAGCAGTATTAATACCAG TGACATCTTTAT

CGCCAATCACAATTGTTTTTTTATTCTTCTTAGCAAATTTTTCTAGATTATCAATCA TTCTTGAGAAATC

AGTTTTCTTAGTTTTTTTATTAGATCTTAACAAACTTGCAACATTTAACATATAGTT TACCATCCTTTTT

_{ATTTTTTAGGTTTTTTATTTACAAACAGTAGAATAATAATGGCAACGCCAATTCC AATAATTGCAGGAA}

GTAAATCTTTAAATATATCCATGTCGAATCACCTTTTATATTTTATTTTTTGTATAC ATATTCCGTATCA

TAATTTTCAATAATAAGTTTAACAGTTCCATGAGAAACTCCAAGAGATCTTGCAATC TTAGCAATTGAA

AATTCAGGATGTTCCATTATAATATTATTAACAGATTCTATAATTTTTTCATTAGTT AAAGAATTATTAG

ACATATTAACTTGGTTATACGTTGCGATACTAAATTTATATTCTTCAAATAGACTAA TAATATATTCTTC

GGAGAATCCTGTATCTTCAGATAATCTTGCTGGAGTCATAATATCATTACTGTCTAA TACAATTTTACT

TAATCTTTTAAAGTCTGATAATCGTGTATCAATCTTCATATCTGAAATGCTCATTTT TTGAAGTCTAATA

GATGAAATATCTTTTCCTTCTTCTTTCATAATTCTTCTAATAGTTGATTTTGCAATT GAAAATTCAACAT

TACATTTTTCAGCAATTTCTAATATTGTCATTTCAGGATTATTACGATAAGTATAAA TAATATCTTTAGT

CATCTTACTAAATTTATCATTATGCTCATAAGTTTCTCTTCTCTCTCTTCTTTGTCT TCTTCTACTTTCTG CACTTGTTAAAACATTTTGACTCATTACCATGATAATCTTCCACCCTTTTTAATTAATTT AATAAATTGT

ATTAATATAAGATTATAAAGTATATCTATGATAGTTTAAATTAAATATATTGTAATC GTTTATCACATG

CCTGAATTACAATAGCATCCCATAAAGCATTATGTTTATCTTCATTTACTATGACAT TAATATATTCACT

AGCAAATTCTTCACGATTAATATCCGGATCAATATTTTTAGTTCTAAATACTGTAGA AATATCATAATA

GTACATGTCAACAAATTCTGGAATTAATGTAGCATCTTTTCCTTTATTAATTAGATC CACAAATAACAT

CCAATCGTATGCCATTAAGTCACTAACAAATACTAGTTTTTCAGAACTATGCTTAGC ATTATATGATAA

CCATTCGATAATTTTATCAGAAACTTCATCTTTAGTTCCATATACTATAGTTGTCTT AGCATTATCCGAT

TTTGATGCTAATGCGTCATGTTTGTTAAAAAATCGAAGTTTAGGAATAACATTATCA TTCACCCAAACA

CTTGATTTCGTTGTATCAAAATTAGATACTTCCGCATAAAATAGTCTACCGTACGTA TCTACCATTCCA

ATACTAATTAGGTCGGCATCTTTTGTTAAATTTGTAAATTCTGTATCAAAATATATC TTATTATCCATAA

TGTACCAACTTTCTTTAATTTGTCTATATATTTCTCAATATAATACTTGATAAGAAA TTATTGAATTCTT

TTATTAATCGATCTAGCGCCTTATCATTAAGTAATGAATTTATATTTATAAATATGG ATTGATTATCAA

TAAATTTATTGATATCTTTTATATCTATAACAATTAAGAACTTACCATTATCATCTT TATATAAAGAACT

ATTGATTGATTCTAATTTTTTATTTATATATAACATTTTACCATCAACAATAAATTT AGGGTTAGTATAC

ACTAATTGAAACATACCATTAGAACATTTCGATTCAATAGGTAAATATTTATACATC TTATATTCATCT

ATAGATATAATATCAATAATGCATGTAAACAAATATCTTTTAATGATTTTTCACCCC TATAATTTATAA

TTTTGATACTATAAAATAAATATCATATTTATAAATAATTATTATTCTAAAAAAATA AAAAATTCGATT

AATGATATATGACATATCATTAATCGAATATAATCTATTTAAGTATAGATACTGTTA CGTTAGATGTCC

CACTAGAACCTATTTGCGATTTATCAATTAATAAATCAATTTTATTCCCAATAATTG CGCTTCCCGTATC

ACATGCTTTAGCGATAAATGAATTACCATTAGGATATGTAATTCTTAAAATACTGTT CATTGGAATTAC

TGATGTATCTACAGCTACAATACGATGACCTTCTGGAGAATAAATAGTGTTACTCAC TTTAGTTCCATT

AGCAGTAATTCCTGTGCTTGGAGTATAATCATCCCCAACCGCATATACTGTCATACG AAAAGAACCAA

TTTTTCTGTATGAAGAATTTTCTTTAGTTGAAACATTCCGTACAGTTTTTTTATTTT TTACTTTATGACCT

TTGTTTAATTTTAATTTCTTGATAAGTTTAATATTATCATTCTTAATATTTTTAATA ATTGTATCTTTATC

TTTAATTTTCTTTGTAAGTTCTTTTATATCAGTAGACATTTTATTACTTTTATTAAC AATATTTTCATTTT

GTTCTTCTAGATTATTATTGATTTTATTCTGTTTTAATATTAATTTTTCCTGACTTT GGATCATATGGTTT

AGATTAGATTGATGAATCGTTTGAAATGCTGTTAACGATAGTAGTAGAATTACGATA ATTGATACGCA

TGTAGTTTTAATATTCATTCGATTCAATTTCTTTTTCTTATGCATAGATTCCTCCAT TTCTATTATAACAT

TAATACTATTTGCTATAGTAAAATTATATATCAAAAAACCGTAGTATATTATTATTG TTTTAATATACT

ACGGTTTCTTATTTTATTTTATATTATTTTTTAAACAATATTACTAAGAATTTTTGG CGTTTTTTCCACAA

AATAAATTTCATCTGAATTGATCTCAATGATATTGGCAATTAGTTTTCTAATAAATC CAACAATATTAC

TGATATGGATAATTTTATTTTCGTTAAGAATTGAGAAGTTATCTAGTAATCCATTAA CTTTTAGATTGA

TATATGAATATGATTCTTTATCAATATAAAATTCAATAAGGTCGGAATCGATAATCC TAACATTAACTA

TATTATACAAATTTGCTTTGTTTTTACTATTAATGTCACTAATAAGTTTATCATAAT CATCTTTATCCGG

AGTATGAAAATAATATGGATTTAAAAGATTAATAAAATTGATCTGATATTCTTTTCC TAAAATATTAAA

AACTAATCCATTTTTTTCTGAAAATTTAGTTGTAAGAACTTTATCTATAATCACTTT CTGTTCCATTTAA

ACCACACTCCTATACCATATTATTAGTATTAATAACTTATTGTATTAAGTTATTATA AAATACCCAATA CGTTAAATAATAAACGTATTGGGAGTATTAATACTAATAATTATTGAATTCTATCTTTAA TTACAACTA

TTGTTTTATGGAAATTACTAACAAATTTAATATTTGTGTCATAATATTTATTTCTAA TATTATTAGGGAT

GTGACCAATAATATCACTATAAATAGTATCAATAGTCTTATCGATATTTTCAATATC CGTATATACATA

ATGAGATAAGTTATTTACAATAATTTTTCCAATATCAATATATTCATTTTCAAACAT ATTAGTATATTCT

TCAGGACGTAGTAAATTCCTAAATAGATTTTCAATATTATTAATAATTACATCAATA TTTTCATCATTA

ATAATATCATCGATATCATTATTAATAATAATATCAACAATTTCATCTACATAATAA TTAACATTGTCT

TTTTGATTTTCAGTAATACCGATTAATCCATCAACTTGCTCTACTTTACCTGGATTA TCATCATAGATAT

TACTATCCATTGATGTTGAAACGTTATCCATTTCATTAACGCTTGAATCTTCTTTAT TCCTACCACTAAA

TAACTTATTAAATAATTTCTTAAACATACAAATCTCTCCTTTTATACTATATTTTAC TATTATTATAATA

TATAAATAAAAAAATGATTAAATTAGTATATCTCCAATCAATTTATATTTTGATTAG AGATATACTAAT

TATTTTTAACTTATATAATCATCGATATTTATTTCTTTAAGTTTAATCGACATATCA TGAAATGCTTTAT

ATTGATAGGTAATTTTTTGAAGTTATCTCCAAATTTTCCCCCAATCCAAACCGTACG TGAGACTTTCAT

CTCATACGGCTTTCCATCTACTAGGAATCTAAACCTAATCTGTTATGTATCTTTCTT TTTAGTAGACTAA

GGACTTTCCCTAATTTATATTTCTATAAATATTATCGGTATCTTATCCTCGCTTTCA ATCCAAATAAAAT

TTCAGTTATAGTCCAGATTAGACTTTCCGAGAAATAAGTATTATATTAATACTTTTG GATCTTCCCATG

TTTCTATAGACTTAGGTTTATTATATAACTTAGGACTTTTCTAGACCATATATCTTA CTTCTTAACATGA

TAAGCTAATAAGGTTATTATCAATGATTAATAACTATTAGAAGATATATTTATACAT TACTGTATAGGA

TTAAGTCATTATAGAAAATTAGTTAAATCTATCCATATTATACTACCCAAACCAAGA TATCTTATCCTT

TTTAATTAAAAGGACAATCTTCTTGACTTCATCCAGCTTCACACATAGTAATTACTT GCTATGCATGTG

GAATATTATTTTCAGGAAAATCTTAGAATCTTTGTTATCTAAGTCCTTGATCAGTCT ATAAATTAAATT

ATATAAAAATATAATTCCTACAATCCCTCATATTAAAATAATGATTTCTGTAGAACA TGTCACACCATT

GATAATCCAGTTAATGCATTCCCAATACCATTCGCAATTAGCCCAACATTCTTAATT CCCATTTGATAG

TATAGTTCGCCTGCACATTTATTACAGATATGTTCAGACTTACAGTATAATGGACTA CGCATTTCAACA

TTCTTATTAATAAATTTACCTTTATTTTCTTCGGTAATTTGCGTTAATTTATCACCG TCTTTTACATAACG

AGTAATAAATAAATTAATATTATTATTTGTAAGTGTAATATTTAAATATTTTTTAGA TTTACAATCACTT

CCATGATCGCCAAGAATTATTGACTGAAATGCAGTGGCAAGTTTTTTCGCTTCATAT CCACCATCTTGA

GTACCAATAGCACGACTTGCACTAGCACTTGTAATAATTTCTGCATATTGATATAGT TCGTCAGGAGGA

ATACCATCGTCTAGTGAAGCCATACTAACTCGAACATCATTTGGGTCCGCATAACTT TTAGTTACACCT

CTAGCTACCGCTGTTTGTTTAAAGTTATTATTAAAACTTCCACGGCTTCCACTATCA TAAATATCCATAT

CGGAAGCATCTTTAAGAATATCATGGGATAATGTTAATAATTCTTTTTCTATTTTAG ATACAGTAACAA

TATCCCCAGAATCAATTGCCTTTTTATGCTTAACAATCAGTTCTTCTTTACGAGATT TTACTTGAGGAGG

AGTCATCATTAAAGTTGTACTAAGTGATGTTGCAATGAATTTAGTTATACCAAAGCC CAGCCATTGCAT

CTTATCAATATAATTACTAAAATCAGCTACAGTAATTTTATCTTCTAATAAGAGAGT ACTTAATTGTTT

ATCTAACTTACTAATAGCCCCACCATCCATTGGATGATTAATATATCCAATATATCT TCCTAATTTTGC

ATCAATAATTAATAGGTTAAAGATATATCGACCTACTGTAGTAGTAATTTTATCTTT ATTAAAATGAAT

ATTTGATTCTAATTCAAAATAATCACTTGGGTCAAACTTTGCATCTTCATTTTTGGT ATATGCAAATAAT

TCTTGTAATTTTTCCATAGTGATATCATTCTCTGAAAGATTAAGAATCTCAATCTTT CTAGCATCACTAA TCTTTTTACCTTTATATGCTTTTTGCAACTATATTCACATCCTTTATAAATTATATCCTT TAATATAAATA

AATGTTCTATTAGATAATAAAATTGTTAGGATCATAGAAAAAAAAAAATATAACCTA GATATCTAGGT

TATATTTCTTAATATAATCTGACCATAAAGAATTAATACTTTCCTTATCTTGAACGC TTATTATGTCTTT

TAATTCAATTTTATTATTTTCTTCAAAGTATATATACGATAATATACTGGAGATTGC ATCATAACCTTGT

TCATCCGTATTAATATAAACGTTATCATCATTACCATAATCCATAAATGTATTATAT GATCTTTTTGATT

TTATTTGTACTGGTTGATGATTAATTACTACGTCTGTTCCATTCCTATCTAAATATG CAGAACATTCCAT

CCAAAATTTAATTTTCTTTTTATTAAATATATTCTGAACTTTTCCTAGAATTCCCAT TACTGCAATTTCT

GCATAGTGACCTTCATTAAGCATTGGTGGCAGTTTATCAATACATTTTCCGTTGAAT CCTTCTTTTCTTG

CTTGGTTCTTATAATAGTTCAATTCATTTAAATTAATATACATCGTAATATTCCCCC ACTAATCGTATTA

TTTATAGTATTATTATTTTTTCACAATTCTTACATTTGGTTCGATAAATTTAATAAA ACAAAATTTCATT

GATAGCTTTATAATAGTATATGTAGTTGCAATCATAAATACAATATTAATGAATATA TTATTGTCATAG

TTCCACAATACTACGTTTGAAGCAATAATTAATAGAATGGTCAGTATTACCGTTATC ATAATTGAGATA

AAGATCTTGTTTACTATACGATTATTCATATCATTTCCCTACCTTACTTTTACTTTT TATAAACATGTCT

ACTTTATTACGAGAATCCAAGTATTCAGAGAACTGATCGATGAAAAGATTTATTGAT ATGTTATATGTT

AAGTATGAGAATGAAATCGATACTAATAAGTCTAGGTAAATATTATTATTTCTAAAA CATACTTCATTA

ATAAAAAGAAACCATAATGATGACGTAATAATAATATTAAATATTACTTTGGTGATA AGATTTCTAAA

TAATTTATCACTAGAATAGATACTTAGTATACTTTCCTCTCTCTCAAAATTAAATAT AGCCATTACAGT

TCTTAACATATTTTTTCTACTTTTAATTTCGATATTCTTAATTAAAAAGTTGCATAA GAATAACACTGCT

TTATTTATGTACATTATATAATCAACCCTTCTTTTTTTTATTTAATCATTATTATAA TATATCATTAAAAC

TTGTATTATTACATTTTTTATAAATTAGAGGGATATGACAAGTTATATGTCATATCC CTCTAATAAATA

TAATTTATGCTACGTAAATAATATATTCCATTTCAATATTTGTAGATAATCCACTTA ATGAGATAGAAT

CAAAAGTCAATCTTGATCCACAACTAATGTTTTCATAAGAGTTTTTAGTTTCATTGT ATCTACCTAACC

ATAAACATAATTCATTGATCATTCCACCACGACATTCACTAGGGTCGATAGTTAATG ATAGACTATATG

AAACTTCTCCAGTAAATGTATTAATATTCCAACCTTTAGAATTACCAAAAGGTTTTG AATTTGTAGCAC

CATTAAATCGTTTACCATAATATTTTACAGTACCATCCGGATCAGCTTGTGGTAAAT AATATTTCATTTT

TTGTTCATCAGTAAGCTCTTTTACAATAGAGGGATTATCTTGAGTTTCAGTATCATT ATCCTTATCAGG

GTCTACTGTAATAAAAGGAAATTTTTGAGCTAATCCATTATCATTAAATTTTGGAGC AACTGGAGTGA

ATGGACTAGCATTAATATCCGCCCCTCCTTCTCCTACTGAGAATAGACAGATTGATC TTGCAGGATCAT

AGACTTCGTTGTATGTTGATGGATGTTTTTCTTTTAATAATGCTTCCATTACAAATA CACGAGTTCTTTG

TAAAATTAAATTATCTTGAATATTGATTACTTGTTTTGTATCTGCATTACGGAAAAT AACTTTTCCTCGA

ATTCCTTTATCTGAATCTGCAGTACCAATATTATCTTCAAAAATTTCTTGAATGTTA TTATCTTTAGACA

TAATGTGGATTACACTTCCTATTCATTTATTTTATAGATATCGATCTTAATCATTTG ATTTAATAAATAA

TTTATCACTAAACGTTATATTATCATCAAGACGTTTTGTTAAGTTTAAACTATGAGA ATCAATTATAGA

AATATAATCCCTAAATAGTATTCCACCTATTTTAGTGACATCCATGGTATCAAACAA TCTTATACTGTT

ATCCATTTTACTATCAAACTTATAAATAGAACTACTATAAACTGTATCGATAGTATA GGATTTAAATAC

TTTTATGAGGATATAAATATATGATTTTACATAATCAGATAGACCAATCGTATTATT TTGAGTTAAGAA

ATCATATTCCCCTAGATTTAAATGATTATCAATACTTTCAACAAGTTCAAATATTCT TTCACGATATAT ATCATCTTTACTTAATGAATCAATATCGTATATATTAATATCTACTTCTGTATAGAAATA TAAGTTTGG

ATCATTATCTTTTAAGTAATCTGTAAACGTATTATATTTTGAGAAAATATCCATATT TAAATCATTTGTA

AATTTTTCATTCCATAATTTATTAAACAAACTATATAGTTTATAATCATTTGTATTA ATAATTGTTTCTT

CTAAGTCTTCCCTTAGTTTTTCATTATATCGGTATATTTTTGCGAAGTCATTCATAG TATATCTTCTTTTA

TTATTGACTATTTCATCATATGAACCAAAAACATCTATAAATACCGATAAATTCTTA TAGTTTATTAGC

TGTTTTCGATAAATATATTCATTGACTGAAATAGCTTCATCAATAGCTGAAGGAATC ATATCAATAACT

TTTCTAAAGTTCTCAATAGTTTTATTTCGATTATATATATCGAAAACGGTACTTAAC CTGTTAATACCA

AGCTTATTTATAAAGTCTCGCATTTCAGACATTATTACCACGTTGTCCATACCAAAC TGGAATATCTTA

TCAGTACTAATATATTTAATATCTACCTGATAATTAACAAATCTTGATAGTAATTGT TTCAATAGACTA

TATTCCGATATTATAGACATTGATATTTTTCTATTTTTATCAAGAAGAATATTCATT AAGTATTCTAATC

CATCATAAATATTACCATTCTTAATGTGATTTTCTAATTTCTTAGAACCGTTAATAC TTTGGATGTATTC

TGAAGTGAACTGCATTTGGTTTTGGTAAACTATTGAAGAATTATACATTGCTACAAT ACTATCAAAATC

TTGGTCTATATCTAAGTCAAATCCTTTCAACTTAAATCGATTTAGATAACCCATAAT ATTTTCCCATTCT

CGTACTCTGAATTTTCGTTTATTCCAGAAAAGATATTTTCTTAATGAAATAATAATA TCATTTACATTTT

TATCAATATCATATCCGTAGGTATGTTCTAAGAATGGAATTTTTCTAATTTTATCAG ACCAATTCATTCT

TTTTAATACCAGTGTTATTAATGCAACAATAGCATCAAATATATGAATTTCACTATC AGAGATATTGCG

GTTATTAAATTTAAAGTCAATATTCTCAAGATTAACTACTTTTGAAGCTTCTTGATA GGTAATATTATT

ATCACTAGCATATTTATTGATTATTGCTCTATTTTTAATTTCTAGGTCATTTAATAA TCCATAAAAGTAT

GATAATTGTTTCGAATTATTAATCAGATCAAGAACAATATCGACTGAAATATACTTT GTATTTATAATA

TTGAATGATTGTTCTAGTATATTTTTCTTTTCAGCTCGCCAATAGGGATCACCTTCA GTAATTGCGTCAT

AATCTACCCTAGGATGAAGCGAAAAATTTAATTCTTCATCAATAGGAACTTTATAGA ATTCTAGTGAG

TCATCACCGCCTAGATTATTTTTCTTAGCAAGCATATACCTATTTATCTGTACATTA TCAAAAGAGAAA

AGATTCTTTATGACATTGAATACATCATTATCTCCCTTGTTACTAATCATTTCATTT ATGAATCGATAAA

TTCTTCGTTGATAATTTACTGGAACAGAATCAAAATAATCTAATCCCCATGATATAA ATCCATTTTTTA

_{ATTTTTTTCTATCATAAGTATCAATATTAAAGTATCCTTCCATAGTCTTATTAAT ATAACGCATTATAGT}

CATAAATATTAGATATTCTCGATATACTTCACGATTATATGTTTGATTACTAAATGC TTCAGTAAACGT

AACATTTAGGAAATAATTAATCGATTCATAGTAAGCTTCATTAAATAAACTTTTATG CCATTTATCTAA

TGTATTACTAGTTTCTTTAAGTATATAGAAATCTTTTGCTCTTCTTGCTGAAGCATA ATCAATATTATAT

CGATTAAATAAATCTTTATAATAAGGGTTTGATTCATTATATCCTTTAATGATATTT GATTTTTCTGATT

CTGAAAGTTCCGAATCACTATCATATATAGCACTTAAATATCTACTAGAATTTAATA GTGATGAAGGA

GTTTCATTTGCTTCTGCCAATTGAGTATCCTTAATTACTAGTCCACGAGCATAATTT ATAACATCTTTTA

TTTCATTAATATCCTAGTCTTTAAATGCATTATAAAAATAATATGGTGTATATTTTC TTAACATCTCTTC

TTTAAATTCATTGACCAATTAAAAACGCCACCATTCTATTATTATTTTTATATTATA AAGAGTTGTTCAT

AAGTTATAATATCTTTTTAGTTTTGATATAGAAACAATATACTATATATTAAAATAA AGTTAGGGTGAT

TTATATATGAATATTAAAAAAATAAATAAGAATAAAACAGTAAGTAATATTGTATCT ATCAGTAAAGA

TGGAAATATAATTCTTAAGGATAAGAATTATACAAGTGATAATTTTTTAGACTCATT CTATATAAAGTC

ACTGGATAGTAAATCTATGAATAAATTTATAAAAAATATAGAATCATTAATTCGAAC ATCATTAGAGT ATTCTAGATATATTGGGTATTTATCTACAGTTCAAAATATCAATACAGATGCAATTATGG CAAATATTA

ATTCTGATGATGCCAGTCTAGAGTTTCATCATTATCCATTTACTCTTTATGATATTG TAGAAATTGTTAT

AAATAAAAATATTGCATTACAAGAAAATTTTACATCAATATCTATAGCTAGGGAAGT TTTAAAATTAC

ATTATGATAATATGATAGGATTATCTAGAGTCAGTAGAACGGTACATCAATTAGCTC ATGCCGGCGAA

_{ATTTTTATTCCATTAGATAGTATATTTGGAAGGGTTAATGATGTTCGTTAATGAT TTTTATGAATATATT}

TATCAAGAACACATTATTACGTATAATAAGATTATTGAAATTTATAATAATAAGAAT TATGATAATGA

TATAACAAAATAATTTTTAGTTATATATTATAATTAAAATAATAACTATTATAGGTG GCGATTATATGA

AAAAAGGAATAGACGATTATATTAATAAATATATAAGTGATGATCCAGAGACTCAAA AAGAAATAGA

TCTCATTGTAAGTAAAATAAATGATTTTAATAATAATTGTATTGAATTGATGAATGA TGAAAATATGAT

CTGTGAAGAAAATATTATTAATGGTACCATTAATGAAGTTAAAGACATTCTATTAAC GTTATCAAATA

CATTTACATCTGTTTATATGGCGAACAGAGTTATTGAAAATATTGAATTATTTATAA ATGGTGAAAATG

ACGAAGAGCTTCATGAATATATTTATATAATGCAAGATTCAATTGAAGATTTTGATG ATATTCCTTTAT

ATGACAAAACGTTATTGTCTGAAGCGATTAATACCATTCAGCGAGCAGAATTTCTAA ATATGATACTC

AAAGAAATACATATCTCAATATATTTAGAAAAAACACTGAAATTATTAAACGATATT ATGGATTATAA

TAGTGATAATTTGCCTTATGATATGTCTATAGAAATTAATGCATTACTGATGAGTTC TGAGTATACATT

ATCAGTTATATTAAGTCAATTTAATCATATTATAACTAAGTCATATACTAAATATCT AAAGATCGTTGA

CATTATCTAATTTTAAACCTAATACCATAATTTTATGGTATTAGGTTAATTTTTTTT TTTATTTTTTAAGG

TTTAAACTACCTAGCACATTTGTTTCTTTATTTCTAATTCTTTCATCAACAGTATTT AATAATTTTAAATT

ACCATAAATTACTACTGCATAGGTTTTATTTTCTTCCGGATTTTTTGTTTTAACAAT TAATTTATCAAAA

TCAACAGAATATTCATCTTCTGTAAGCATTCTGTTATTTGCAAATATTTTTACTTCA ATACATTTATCCA

TATTTCCATTATTTTTTTCAATTTCTTTAGCAACACGAATTAGTCCTGAAGACATTA TTGATTTAATATC

CAATTCATCATATGCTACATTAAAGTCAGGAATAAATTCTGAGAAATATAAGATTTG CTTTTCATTAAG

AGTTGGAGGTATTAAATCTTTTTGAGTTATAATATTAAACTTAAATGTATCACTATT ATCTATTTCTGGA

ATATCTTTTATAATATTTTCGTTTCGCATTTCTAAAATAAATGATCCCGGCATCCAT AATTCTGCAGTCA

TTGCATATCGCACTTCAGAATAAGAATTGATTAGATTATTCATTATTTTTTGAGAAT TTGCTAATTCTGG

ATATCTTAACATGATATTTGCAGGATACTCGCACATATAGGTAGGATTATTTGTAGA CATATTTATTTT

TTCTATAATTGGGTTTAGTGAATGAGATAATAAATATTCACGTAATTTATCTTTATC TTCTTCATTATCA

AAATCTAAACCTAATACATTACATATATTCAATATAAATGATAATGGTATTTCATAA GGTATTCTAATA

TCATTAAGGTAATTTACTCCGTTATTCTCAAAATTCTGATTTAAGAAATTTAAGTTA TTCCAAGCAGAA

AGTTCACTAGGGAGTTTCATGTATATATCAAAACGTAATTTTATCCGATTAGGAATA TAAAAAATACG

AATATCATTTTCATGATCTTCAAATACCATTTTGTATTCTTTGTGTTTATTACGATT TTTTATATAATATT

GATGAGTAGACCAAAAAGGTAATATATCAATAAATGTATCACCTAACTCAAATTTAG GGGAGATTCCA

ATGTATGGTTTAGGCATATCAGTAAATAACCCTTTACCATTACTAAAATTAGTCGAA TTTAATGATTCA

CCGATATATACCTTTTTAAAATATTTAGGTGGAAATTTGCTTATAAAATAGTTTGAT ATGAATGATGAT

ACGCCACTAATAACATTATGTATAGATGGACTAGCAGTACATAATGCTACACTATTA TTATATTCAGAT

CTTGCAGGATCTAACATAAGAGAATCACGCCTTTCTATATAATGTTGTTCACAAAAC AAAAAACCCCT

ATTACTATAGTTATATAGTAATAGGGTAAAAGATCAGAGATTGTGGGATCTCTAAAA GTGTGAAGTAC AGAAAGCATATACAATAGGTTAAAAAATAAAAGGTTAAAAAAATCCTATCGTATAATATA TTATTTAG

AAAATTACGCTTAAAAAAATAATATTATCTCTAGGTACTGATGCTCGAATTGTATAC ATGTTTGAAATG

ATGAATTTATCAAAGTCGAAATCTTCTCCAACAATTTCTTCAAACTCTTCATTTCCT CTAATAAATTTAT

TAATGATAATAGTAGTTTTATTAATAATTTCGTTAGTCAAGATAACCTGTACTTTTT CTACATATTTATT

CATGTTTTTATCATCATTTTGATTTTTAACTTCAGGAAAATTTTCATTTTCCGGTTT ATTTAGTTTTAATA

CAAATTCAGGATTATCCTTATTAATAAAGATTCTTGAATTATTATCTTTAAAATCAA CTTTTTCTGATTC

ATCAATAATTTTTCTTAATTCATTAACTAAATTTTCTTTACCGATAAAACTAATAAT GTTATTTCGGATA

GCAATTTCTTTTCTGAGTTTAATCAGTTTTTCATCATCAATCATCTCATTTAGTCTT TTCTCATTTTCATT

ATAAATCATCTTGTATTTTCTTCCCTTCTAATTCCTTTTCAGGATTATATGTTAATT CACTATTAATTTCA

TTATTTTTAATTTTCATTGCAAGATCTAATATGTCATCATCTAGTGTTTTTTTAAGT TCTTTACTTATGCG

TATATTTTTTGAATTTGGGTTTTCTTTAAATCTTATTATTAGATTTGTTTCTGGATG AGTATTATAACGTT

TTTCAGATATTAACCGATATACTTGATTATCATCTTTCCATAGTATTTTATTTAATA AGTCCATTAATGT

TTTTTGATAATTATCGATATCTGGTTTTTTAATTCTTTTTTCCTGATTTGTCAACAT TAGATATATTTTAT

AAAGGCTATTTCCAAACTTTGTTGGAATATTACTAAATATGGATTCTAATTCTATTG GACCTTCAAAAG

CGTTTTCATTAAAAGGTATTTTATTCTTATGAACTGAATTATATTCGTTTATAGATT TAATTAATATTTT

TCGAAATTCATTTTTATACCCACCTAATGGATCGTATGTGCTACCAATGATATTAAA TCTATGTCGTTG

ATACGGTAATATTTCCCTATCAATATTAATATGTATTTCATTTTTATCAAATTTAAT GATATCTATATTT

GCATTTAAGATATACATCTTAAAATTTCTCGATTTTGGTTTTTTAATTTTTATATCC AAAGGTTTTTCTTC

ACCATTAGGAATAGGTCTTTTTTTCATTACTGCTTCTCACCTCCAAAAGTATTAGTA TATAAATAATTAT

TATTCAATAATTATAATTTTTTAAAGTAAAAATATACTCATATCAATCATTTTAATA TATCACGATATA

TGATAATTAATTAATTGATATGAGTATATAAGTTATATAAAATACTGATGCCATTAT TAATATTAATGC

AGTTACTATATAATATATTAACTGCATTATTTTGCTTTTCAGATCTATTTATTCTAA ACGTCATATTCAT

ATGACGTTCTATTTCTTTAAATAATTTATCCATAAAGTTTTCAATATCAGAAGTAGT TTTCTTAATGGGT

TTAATTTCTTTAATTATTTCATTAGTATATTTATTCGTTTCATCTGCTTGTTCTTTA ATTGCATTTAAAAC

AGCATCAGTTTTCTTCTTATGTGCTTCAAATTCTTCTTTTGTAATATATTTTTCTTT ATCAATATATTTAT

CGTTATCTTTTCTTTTAAATATCCTTTTTAGTAGTGCAGTGAACTTTTCCATCATCC TTAAACCCACCTT

_{ATTTTTATTTTAATAAAAGGTCGGGTACGATATTAATAGCTGAAACAATTATACC ACTCAGAGCAGGT}

AACAATGCTAACCATATTTTATTTCTGCTTTCACTATTATCTAATTTATGACTATGT GATAATTGTGTTG

TTTCAAGATTCCCTATTCGTTCATCTGAAGATTTTGTAAATGAATCTATTTTTGTCC TAGTTTCATTTTTA

ACTTCCTCGATATTTGAATTAAATCTTTCACCAAGATCATCAATTTTATTAAAAATT TGACTTGAGAAA

TCATCAAATTTTTCTTTAATATTATCTACATTTTGACTTATTTTAGCAATCTCTATA TTTGTATCATTTAG

TTTTGTTGAATTTTCATCAGTTTTCTTCTTAATATCTGAAGTAGTTTGATTATAGTT GTCGATAAAAAGT

TTAAATTCATTTCTGGAAACTAGTTCTTTTTCTGAGTTATTTGCCAAAACCTCACCC CCCCAGTTATAGT

AGCCATACCGTTAAATACCGATATGATTAATAGACGGTTAAAGTTTGACTTAATGAG AGTATTTGTATC

GTTTACTGCAGAAGCATAAATTATCCATGCTATTGTTGCAAAGAAACATGATATCGC TATTATAATATA

TCTAGAGGGTTTCTTATAAGATATAAACGCCGATATAATGAGTAATGAACCAGTAAC AACAAAGATAT

ATGACCATATAATTATGGGAAATACCCTATTTAACATAATATATGTTTCAGAAGTAA GTAATACACTA GATTCGGCAATATTAAAACTGATTCCCGTACTTAATGATAATAATCCTAATAGGATTAAT AGAGATTGT

TCCATCAAAAGAATATAATTAAATTCATTCATAAATTTTTTAATTATATTTTTCATT ATAATAAACAATC

CTTTCAGAAAATATCAATAGCACTTACCCGATTTAATAATTCATTCCACTGAGCTTC AGTCGGAAATCC

ATTATCACCTTTTGCACCTTTAAGACTAGCTAACCATTCAGCTTCAGTTCCACTAAA TCCAGATGCTTTT

GCTAGGTCGTAAGCAGACTTACCGTTATCACCAGTGCTTCCTTTATCGCCTTTATCA CCTTTTGCGCCTT

TAATACTAGCTAACCATTGAGTTAATGTACCGTTAAATCCATCAGCAACTGCTAAGT AGTAAGCAGAC

TTACCGTTATCACCATTATCACCTTTTGCGCCTTTAAGACTAGCTAACCATTCAGCT TCAGTTCCACTAA

ATCCAGCTAATTTTGCTAGTTCGTAAGCAGACTTACCGTTATCTCCAGTGCTTCCTT TATCGCCTTTTGC

ACCTTTAATACTAACTAACCATTCGGCTTCAGTTCCACTAAAGCCGGCTAATTTTGC TAGTTCGTAAGC

AGAATTACCGTTATCACCAGTGCTTCCTTTATCGCCTTTGTCGCCTTTTGCACCTTT AAGACTAGCTAAC

CATTCGGCTTCAGTTCCACTAAATCCATCTAATTTTGCTAGATCGTAAGCAGACTTA CCCTCTTCACCA

TCAACTCCGGGATCACCCTTTGGTCCACGGTCACTATCGGAAACGGTATCATCTACG ATATCTTCATTA

GGTTTATGATAGTTAACTTGAGATATTTCATCAATATTACTAATTACATTAGTAACT CTTCCCGCTTCAG

AATACGTTAATACAAGTTCATCACGATCATATTTTAATGTACCACTACGTTTAATAT CTTTTACTAGTA

CTCGATGATCTGAGTATATTGATGTGATTATTATTTCATTTTTGTTATGTCTATCGA TGTATTCTTCTATT

CTATATCCTATAGCCATTTTATTATATCATCCCTTTCGTATAAAGAAACCTTTATAT AATTTTTTGTTTT

ATATATTGGAGTTCTAAATATAAAAATTATTATGATTTGTATATATTAATAACATCT ATAATTCTAAGC

TGTGCTTCTTGATATAATTTATTCTTCCAATCTTCACCTAAGTCAATAATTTTATTT TTTGGTAATGTTTC

TAGTAATTCAATCTTATTTTCACGTATATCGGTAGTAATTACATCATTATCGTCATA TACGGTTAATGAT

TTATAATTATATTTATAAAATGATAATTCTATAAATCTACCTATATCGTTTATATTA TTTTTTCCTATAA

CTACTAATTTAGGTATCATATAATCATTATAATCAACTTCAATAGCATTATCGTTAT CAATATATTCAA

TAGTTGTATGAATTTTATCATCTTCAGTAATTACTTCTGGAAGATTATATGGTTTAA TACTGAAGTCAA

AACCATATTTTTCAGAATAGTTATACGTATCTGTAATATTAACAGAATAGTTTCGTA TTCCTTCATTTTG

AATTGAATTAATATCGTCTATATTATTAAATAAATAAATATTATCAATATTTGGTAG TTCTAAATAATG

ATAATTATTGAATTCTCTTTCTAGTACTGTTTCACTAAAGAACATTGAATCAAAAAG ATAATCATCATC

ATTGTTAGAAGTAATAATAAACGTATTAATACCTTTATTAAGTTTAATTTTATTAGC ATATTCGTAAAC

ATTTGTTTGTTCATTATAAATGCTTAATCGATCATGAGATATACCTTGACTATTATA TTTATACGTATAT

GACAATCCGTTAATATTTACTTTTGCATTACGATTATATTTATCACTAGGATTATAT CCAGTAATATATA

CATATTTCTCAATATCATTTTCTAGGTTAATCTTAAATTCGATATTACCTTTATTTA TCTTTACTAATTTA

TTAGATAATAAGTTATTATAAGTATTATCAACAATCTCTGAAGTATTATCATCATTT ACTGTTTTTAATG

AAGATGATAATTCATATCCTGTAATATTTCCATTAATTTTTATAGGATCGATGAAAT GATTATATATTG

GAACATGGTTAATAATTGCTTTTCTAAGAACTAAAATATTAAAATCTACATTTTTTG TATTTCTAGGTT

GACCTGACTTTAATAATATTTCTTCAATATAATCATTATGGTCAGCATTAATAATAT TATTGTTGATTTG

ATTCTGAGTATACATACTATACTGTTTAGGAGTTATATCTTGCCATACATTCTTGTT ATTACCATTAGTT

GTTAAACTTCTTTCAATATTATTAATAAAGATTGAAGATGTTTTAGATGTCAGATTA TTACTTCCCATAT

ATACCGTCATATTGTAATTATTCATTTCAGGAATAAATATCTTCATTCTTAAATACC CATCTTCTAATCG

AACATAACCCTTTCCAAAATATTTTAAATAGTCAGAAGTCATTCGTGATCCAGAAGT TTTAGTATCTTC ATATTCAAATATTGTTCCATCATAACATTCATATACATAAGTACCGTCAGCTAGTATAGA CGGATATAT

GACTCCATCATTATTGATATAACCATGAGTAATGATATCCTGATCAAAAATAATATC TTTTGGATAGTG

TGGATGACAATAACACTCTCCATTACAATTACACCCATTATCACAGTCATCATCATC GTCATCACCATT

ATTAGGTGGAGTAAATTTATTATTAATGTAATTTACCATTGTTATACTGGTAGGATC AACAATACTTTG

AACTTTTCCATTCTTATCAGTAAAATTTATTTTAAAATCTTTATGTTCTAATAAGCC ATCATGATTAATA

TCTTTAATTAATGTCTTAACATTAGAATCGATTGATGTAATATCAATTAATCCTGAG TTATGATCATCA

ATCATTTCTTCAATACGATAAACTTTCATATTTTGTTTCACCTACTATCCGTTTAAT ATTATATTGTTATC

TTAAAAATTTTAGGACTTTTTGACCTATTCCATATTTAATATCTTTAAATTTATTAT CTAATGACCTAAA

TGATAAAACTTGGACTGCTCTATCCCTAGTCATCAACAAGTTTGTTTTAATACGTTT CATTAGGTTTAAT

TCATCATAACGCATTCCTGCCATACACTCAATATATGATGTTAATCCAATATTATAT CTTAATTGCTTA

ATACGCTTAGAAGCCATTAGGTTAGGATATAAGTCACGTACTTGCATAGATACGGTT ACTTCACGAGG

AAAGTTTTCAGCAGTCCATGTTTGTTCTTCGCCACGAACCATATTTATTGATGATAT TACGCCACATTC

ACATTCAAATCTTCCTGGACAAGACATTCTAACCAAGAAAGGTTGTTTATAACTATA ATATGCGTCTTG

TAACGGTAAACCTAATACCAGTAAAGATACAAATGGTACATATACATAATTGAATAT CGCTCTAGGAT

CTCCATAAGGAGTATAGAATCTAAATTCTAAATTATACGATCTATCGAAAGTAGAGT TTGACCATAAG

TCTGGATAGTATAACTGAGAACCATCTAGATTTTCAGTAAACGCACCAACTAAGCTA CCCAATACCGG

AATTGTTTCAATAACGTCTGTTATCATATCCTTGATTCCATCAGTAATAGCACCCAA TAATCCTCCGCC

GCCAATTCAGGCAAGAGTTTTATTTTCTCTAATTTCAGCCTGTTTACTATTAGATTC ACTAGCTAAAGA

AGACTGAGAATAATCATTAGATGAACTTTCTGATACGCTGGTTGATTTATTTGCATA GAAAGCAATGC

CGTAGTTATCACCATTATTATATTTACTAAAATCGAAAACACCTTCTAATCCCATAG AATGATATATAT

AGCTTAGTATTGTTTGTACATATCGATAATACTCTTCGTAATTTTGTTTAAACGATA TAAATCTTCCATC

ACTAAACTTATTTGCATTAATCATTGGAAAGACATTATCTTCAATTTTCTCTCCAAT ACCGAAAAGATT

AAAAGTGTTTCCTGACATACTACCAAATAATTTCTTATTTAGTCTAGGTTTTCCGGG AGTAATAAATAT

TACTGGTAGATCATTTTCGAATGTATTTCGGTACACTCTAGAGTTTGCATCATCTAA TGGACCATATTT

AAGTGGCATACCTAATACCCTTATATTATCTTTACCATATGAAGCATCAAACGTATC TATTTTAGTATT

TCCAAAAGCATTAATAGTTTCTCCCATTGCATTGACATATAGACCTTCATTATTAAC TTGTGAAGGGTC

AATATCATCTTCTTGCATTAGTGTGTCTCCCTCAACTCCACTGTCTGGTTTTACAAT ATAAAAATCATCA

TCTGAATCCGTATTATTATTAGAATTTTTATTACTTACTAAATCAGGCATATTTTCA CCACTTTCAAAAT

AAATTTTCCTTGAGACCAAATTTAATACATTTATGGTCTCAAGGAAATAAAATTTAA TATCCCGCTAAT

ATAGGAGTTATACTATTAGGATCAAGTTTAAAGCTTGGTTGATCTAATTTATTATCT CTATCATTTTTAT

GATCATTTCTAGTTTGTTTTAAGATGTTATTCGTTTCATTAGTTAAGTTATTATTAG TTGCTTCTAGTCTA

CTAATATTTCTAATTTCACGAATTAAATCACTCAATTTGCTGATAGAATCTTTATCA TTCTTATCAATTA

ATTTATACATCTTATCGAGAATATGATTTACTTTTTTAAGTTCATCATATTTTTCTT TATCATATTGGTA

AGGTTTATTAGGTTTAGCGGAACTTCCATTAGATCCATTTTTACCATTAGAACCGTT AGCACCATTAGA

TCCGTTTTTACCTCCGGAACCATTCTTTCCACCGCCGTTAGGTTTAGCGGAACTTCC ATTAGATCCGTTT

TTACCATTAAAACCGTTAGAACCATTACCATTAGAAGAACCACTAGAACCAGGACTA TTATCTCCAGA

ATATCAACCCTTAGAGCCACCACTTTTAGAAGGTTCAGCGGTTGCTGAAGTTGAATT ACTACCATCTTT ACCATTAGAGAAGTCTTCATTATCTCCTTTTAGACCGTATTCTTTAGCATATTTACTGTT AATACGATCA

CCGATAGCTTTCTTTTCTTCTTCAGTTAGTTTAAAGTTAGCTCTTGATTTTTGTTCT TCAGTTTCTTCATT

AACTTCTCCAGTACCAGACAGTTCTGCACTACCATCAGCAGTACCTCCAGTGTTTCC ACTAACTCTACC

AAATCCTACTAATCTACCAAACCAATCTGCAGGCATATTTAATGCATCACTACGAAT GTTTACACCTTT

ACTAGATTCAGCATTGATCATTTTCCCTTCACTGATATAAATACCTACGTGGGAAAT AGAACCATCTGG

GTTTGCTGAGAAGAATATCAAATCACCAATAGATAGTTCATCTTTTTTAATTCTTTT AGTAGCTTTATAT

TGTTCTCTAGAAGTACGTGGAAGTTTCTTACCGACAGAATTGTATGCATTCATAACT AGACTAGAACA

GTCAAAGGTCTTAGTTTTACCTAAACCAGAACTTGGTCCCATTGAGTATGGAGTACC GATATACTTCTT

AGCATATTCTACGTCTTTATATCCTATAGATTGTCCGTCAGTTTTATCAGAACTTCC ATTATTGGACATT

ACAGAACCTAAATTACTTCCAATATCTTTACTGGTATTTTTATTTTCTTTACTAGAC GATACTTTTTGGT

TTGTAAGATCTTTTAGTTTTGCACCCTCTTCTTTAGCACGTCTTCTTAATCCCGCTT CTTGATTGGTTCCT

GCATATTGACCCATATATTGACTTAATCTTTGTTTTTGGACTAAATCAATAATTTGA TTGTCTGATAGTT

TACTAATATTTTTTCTGGCTAATGCACGTTTAAATAGACTAGTTGCACCTCCAGCAC CATGCTGTACTG

AAGCACTTAAAATTAATTCTTGAATACCTCTAGATCGACCACTTAAATCAGTTCCCA GTGCTTTATTTA

TTTTAGCTAGTCCTGGATTATAGAAGTCTTTTTGGAAGTATTCTTGTTGTGCTTCAC CAAATGCTTTATT

TTGTCCTAATTTTTTCCAAGAAGCATCAAAGCTAGATGAACCTGGAGAACCACTAAG CTTTTTAGCAA

GGTCTGGATGAGCTGATCCTAACCATTTAACAAAATTAGCCAGTGATCCTTTAGTAG ATGATAATTGGT

AAATACCGTAAGATTTACCGCCGGCATCTCCAACCCCACTAGAGATATATCCCGCAC CACTAAAGTCT

TCTTTACCAGTTTCATAAAATCTGGCTACTGAACCAAAGTCTTTTGAAAGATTCTTT CCAGCTCCGGAA

CCGCCAGAGTTTCCACCAGTCGATGCAGCATTTGCATTAACGCTACCTAATCCTTTT ACAATATCTTTT

AATTTATCAGTAATTGATGAGAAGAAATTGCTTATTTTACCCCATACTGATTTAGAT GGTTTATTTGGA

TCAAATCCATTTTCCGCCATATTATATAATGCTGCAACCGGAGTAAGACTGAATAAA GATTTAGCAAA

TGATTTAGGATTCTTTTTCATATCTTGACCTACTCTAGATGACATTAATTTACTGTA TTCAGAACCCATA

TTCATAACCATTCCTAATGGAGTAGCATCTAAAAAGTCTTTAAACTTACTTTGTTCT TTACCATCTTTAC

CTTTATCATCTTTCTTTTTCTTTCTAGCATCATTGAATTTTTCAGCAATACCCATTG GAGTTAATCCGTA

ATAGTGCATCTTTAATCTTATTTTTACGTTCTTCGGATTTTTTCTCTTTATCATTCT TTTTCTTTTCTTTTT

CAGCTTTATCACCTTTAATTAAATCCCCAATAGAAGGTAATTTAGGAGTGCTTGCAG ATTTACCTGATT

TAGCACTCGACATTCCTTTTACAATTGATCCTACTAATATAGAACCTAATATTGCTG CACCGCCAACAG

CTAATGCCGGTCCGGCAATTGGAATTCCAGATACTAATGATAGTAATGCCCTTCCAC CATTTCCTGCAA

TCCTAAGAGCTGATGAGATTCCAGATACTAATTTTTCTCTGGTTGCATTAAATATTG CAGTTCCTCTTTC

AGTAACAGTTCTAAATGCTTCAGTTTCACCTAGACTTTTCATTCGAAACATCATTCG AGCAATTATTCC

_{TTTTTTACTTTCTGCGGATTCTAGTGCAATATCTTTAGTTGCTGAAGCCATTCTC ATTTTAGCTATTAGA}

TTTTCAGTTTTTTCACGAATGGAATTGATTGTACCCATTGGATCTTTTACTGATGAA ACAATTGATCCTC

CAACTTTTTTAGCAGTATCCATAGCAAGACCGCCTGCATTTTTGACCATTACACCAA ATTTTGTATCTTT

AACCATTCCCCATACAGATCCGGCTGCATTAATGGCTCCAGATATAGTATCTTGGTT AATAATATTATC

GGGTTCACCGCTAATGATATCACCTTTAGTTTTATTATTAAACATATTCATACGATC TTTGGTTTTCTTG

ATTTTATCTTGCATAGAATGATACTTGGATACAATTGAACTACCTAGTTTACTTGAA GGATTTTTAAAT GCCGAGCTTGCATCTTTAATTTTGGTTCTAGAGCCATAATCCTCACCGACTGAAATATCT AAGATATTT

ACAGGGTCGCTTGCGTCAGGAGTAACATCTTGACCATTCGCATTTTTTACAAAATCA CTCCTAAGGTCT

GATACGCTTGATGCAATAATTGACAGATACCCTAGTTTCTTAGATATYTCTASKRAG AATAWWTMTCY

WCTYMRYATMMTTWTMAWTAWWTCYASTAAGAATGCARMATTAGAATCTATGATASM GTKRAKCW

RKWATCGTCATMAYGAGTWATATTWMMKRTASTTTCATTATCAAATAATCCAAATAA TGCATTTTTT

ACTGATCCTAGAGGAGTCTCTGCTTGTAAATATCTTTGACCTTTTACTTGTGTCTTA AGAACATTTCTTG

AAAAAGTTGCACTATTACCATCTATAATCTGTGATAATTTTTCATAGATGTCTCCAT CAAACATGTCTT

TGTTATTATCTAATGCAGTACTGTTTTTAATATTATTTTTAGATAATTTGATAATAG TATCTTTAATATT

ATCATTATCGATTCCTGCTTCACTCATCATAGATTCTAATGTTGCATTCTTACTAGA TTTATTTAAAAGT

ATGCTGAGTGGAGATTTATTCTCCGTAGAGATTGCTCTATCCATTCCAGAATTAAAG TTATCTTTAGCT

TTACTAGGATCTAACCATTTTCCACTCTTATAATCATATACTAATTTTTGACCTGAA GAAGCTTCTAGC

_{ATTTTTGCTAAATAACCTGGAATTACCGTATTAATAGTATTATGAGTTTGAGCAT CAAAGTTAACAGGT}

CTGTCTGCTGAAACTCTAGCCATAGAGCTTACTTTTCCTAGATTAGCAGGACCAAAT TGTCGATTGAGT

GAAGTCATTAGTGGATTTTCACCAAAGATTTTCTTAAATTGACCACTAATGATACTT TCGTCACCTTCA

ACAAGATTACCTAGTGCTGAATGTATTTTTCCGCCAACTTTACCATTGGGATTAGTT CGATTAAGCGTA

CCTTTAACCATTCTGTCAATTAATCTTTCTTTATTTTGGAATGGTCCAATTTCACCA GTAGATAATCTTT

CAATAGTGTCATATATTGATGCAGGTATATTTGATACATTCTTATCAAAATAATTTT TTACTCTATCTCT

TGCATATCTATTTGCTCGTTCATTAATATTTTTAGAGATAGAATTTTTTGCATTTTT AAGTAAGTCTTTA

GCGCTTGCATTTCCAGAATTTAGACTACTAAGTTTAAACATTGATGATGTTATTTTA CCTATTCCAAAT

ATACCAGAAAGCATATCATCCATTAGACCCACATTATTGATACTTGCTTTAGCGCTT GCTTGAGATATT

CTATTCATTTTTTCTAATAATGTAGTAGATTTAGAAGATTGCTCGATTAATTGTGAA TAGAATTTGATA

TTTGTTTGATTCATTTTATTTAAGGTATTATTTAACGTAGAAAATCCTCTTGTATTT ACCCCAACTACTG

AACTTGCTGATACAATAGTAGATTCAACAATTTTATCAATATTTTGTTCTTCATTTA CATCTTCATTATT

GATATGATCATTATTATCTTGAGGAGATTCGGTATCAATAATAACTTCAGAGTTAAC GCTTGAAGTATT

ACTTGATTTTCGATTCATTTTATTTAATGATCTACTTAGTATATCTAACGTGTTTTT ACCATAAGCTTCA

ATACCCAAATTATCTTGGTTCATTGAATTATTTGAAGTTCTATTATTCTTACTTTCC AGTTTATCGTCTA

AATCTTTAGATATACTTCGGTATATATTATTAGCAGACATATTGGATGCAGGAATTC GATTATTTCCTT

TTCCCCAATTTTTATTACCTTTATTCATATTGTCAATATATTTACTTCCCTCTTTAA AAGTGCTATCAATA

CTTTTATCTGCCATTCTAGTGTCTCACCAACTTTCATATGTAGAGATTAAATCGCAT TATTAATCTTCTT

ATATATTAATGTTTAAGAATAGTAAAAATCTGATAACTTTAGAAAAAAAAAAAATAA CCATATAGAGA

TAATATCTCTATATGGTAAATATAATTTAAAGATCAATATTAAATTGTGATTTTTCA GTTATAAGAGTA

TTTAATTCTTCCGCACTATATTTACTATAACGTTTATTTATAGTACTGCTAATATAT TTTAAAATATAAA

CTAGATTTAATAATACGCTAAATCTTCTTAATTCTTTTTCATCTTTAGATAATTCTT TTAGTTTTTTATGA

TATTTTCTTTCAGGATATTGCCTGCGAATATTAAGGAAAAGTATTTCTGAAATTACA TCATTAAATTTA

TCTATTTGAAGCTTAGTTTTATATTCGCTAGGTAGTTCTTCTAGAATAATCTTTTTA AAATGATCCTTGT

TTAGATTATAATCTACAATAAGATGAGTAATGACTGAACCAATATATAAATATATAT CCATAATTTCTA

AGATAGCTAATTTTTCATTATCCATAGATTGATTGTTTACTTCATATAAATATTCTT GTACTTCTTCCAT TATCTGAGGGTAAAATCTTTCTAGCATTTTACATTCTGTTTCTTCTGGAAATTTATACTT AGATATCATA

TGTTTTTGATTTTCAATAAGATTTTCTATAGAGAATGAGAAACTATTGTTTTCTTCC GTAATAATTGATT

TAACTTTATAAGCCAAATTTACAACACCCACAATCTGTTTATTTATAAGTATTATTA TCTAAAAGGGTC

TTGGTATTAATCTAAATTCCTTAATATCTTCTTCAGTATTAAGATTAAATTCAATTT CCCACTTATTTTT

ATTTAATATTTTTCGAATATTATAGTCAAAAAAGAATTCGGCAGTATCTATAAAATT TCCTAAAATACT

TGTTCTAAAGTTATACGTAAAAGATTTTCCAATAATAATCTTTTGATTTATACTGGT CGGTATTTTCCAA

ATTCCATTGATATCAATTCTGAAAAGATTATCTGGATCATAGTAAATATTAGAAAAA TAATCTAATATT

GTTTTAATATCACCTATATTTCTATTATAAGGAATAATGCTTTTCTTAGTTTTCTTA TGGATAATTTTTA

ATATACCGTCATAATTTTTTGTTTCCATAAGCGACATGCCTTTCAATTAATTTTATT AATAATTTATTTT

TGAAAACTGATTTTTTAGATATAAATTTATTCTAATATTAGAGTTTTGTATTGAATG AGTTAGATCTAT

GATATTCTCATTACTATTACCAGAATTATTTAGTACATTTATAATTCTTAGTAAGTT TTGTTGACTTTCA

GGAGTTACCTTCATACTCATATCATTAATTATATTATAATCTAAACTTTCTTTTGAC ATATTAATATCAA

TAGAATCAATAATATTAATATTTTCTAAAGATATATCTTTCATTCTTTTATTATCCT CAATATCCGATAT

AATATAACTAAGATAGAATATTGTCCGTAGTTGATTTATTCGGTAAGTATTTTTATA ATGAATGTTTGG

ATACGTTATCATGAATGGTGGTTCAATCTTATCTTTATATTTAACATTATTATTGAA TATTTCATCAATC

TTATAAACAATATCCTGATACATTCCCCTATACATTATGTCTTTATTGTAACAAACA CTGGAATAGTAT

ACTAAATATACATTTATAATTAAAAACGAAAAAATATTTATCATTAGAAACATTTTT ATTTCATGAATA

TTATAATAATTTATAAATGTACTAAAATTAAAAGATACTAGTAGTATACAAGTATTA ATAGCTACTAG

GTATAAAGGATTCTTATAAATAATCTTACCAATAGTAATAAATTTATATTTCTTTAA CAATTTAGATCA

CTTCCATTTCTTTATATGACGTGAATATATTATTGTATAGAAAAAATATAAATGTAC AATAAATATTAT

AGTGCAGGTAGTTATATCTATAATAAAATAAATATAACTACCTACACTGATTCCCCG ATTTAACTAATA

CAATAATAAAAAATTGTTATTGTTGTCTATGTTGTTTGTATTTCTCTTCAAACTCAG AAGTGTATGATTC

ATTTAGTTTGGAGATATCATAATCTTTACCGTCATCTCCAGTGAACGTACCATCCCC ATTATCTGTTCCA

CGAATCTTATCATAATTCATTACGCTTGCAAACATACGAGTTCCTGGCATACACAAT GTTTCAGTTTCA

CGGACTTTACCAATATGAGCATTTGTTTTCTTACGTGAAAATCCAGTAGAACCTACA CGAACTCTTAGT

CCATTTTTAAGAGTCTCATCTAAGATATCCCCAAAGGCGGTAATCATATCAAATACT TTTCGTTTAGAA

AGATCATCTTCACTAAAAGATCCATCAGCAATCAGTTTATCATAAAGAAGATTTACT TGATCGTCCTTA

ATCAACATATCTAATTTTTCACCACTATCTGTCTTTTGATCAATAAGTTTATTAAGA GTTAGATATTCAC

GAGATTCTTTTGGTTTCTCTTCTTTTTTCTTTTTAGATTCTTTTTTAGGTTTATCCT CTTTTTTATCTTTTG

TTGAATCTTTCTTGACTGATTTAGTAGTTTTAGATTTTTCTTTAGGTTCAACTTTTT CTTTATTAACTACT

TCTTCTGAAGAAATCTTAGTAGGTTCACTTTCTTCACTAGTTTTTACCACTGGTTTA ACAACACGTTTCT

TGGGTGTTTCTTCTTTAGCTTTACTTTTTACCACTGGAACTACTTTTTTATTAAGTT CAACTTTTTCTTCA

CTAACTGCTTCTTCTGAAGAAGGTTTAACTGTACTCTTTCTTACTGCTCTTTTTACC ATAGGACGAACGA

CTTTCTTCTTTTCTTCTGCCATTTAATTTACCACCTTTAATTTATTTTTTGAAATAT TATTAAATTAGTTA

TTGAATAAAAATAATCTTTTAATTCTTAACTTTATTTAATATATACCCTATTTTATA TTAATGTAACTAC

CTTATTGCCAACGATATTTAACAATATTTCACGTTTATAATATATACTTATAATATA GGTTTAAATTTTA

_{ATTTTTTAAAGAAAAATTTTCATAACATATTAATATTAAAAATTATATTAATTTG ATTTTCTTATGGGAC} TCCGATGGGACTCGCAAAATCTGGACTGAGCCTAGACTCCTTATTAAGATGCTTATTAAT GGACTTTAC

TATTTTAAATCGAATTCCAACGTTTGTTAAAAGGTGGACAAATAGAGGGTAAAGAGC TTGCGGTATAG

TAGACGATGGTCTCACTGTAGATGTAAGTAAGTTTGTAAAGATTCTTTATTATTTTA CGTTTTATTCTTT

TTTTACTTCCCACACTTGAAGAGTGTTTAAAAGGGGGGTTGGGGGGTTTATTGTTAG TTTAATTTTTTC

ATAAATAATTTTAAAATAAAAATTATTTTTATTAAAAAATAATTTAGAGTGGGTGCT GGAATTTCAGCG

CTCCGCACTTCATTCCGATAATAAACAAACCGAGAACCTGAAGTTGAGTATTGTATC CAATTATCCTTA

ATATCAAAGAATGTTTATAATAAGTAATATACAGTAATTAAATAATAAATATTGTAT ATAGGAAATAT

AGTATGAATATTATTCAATATAATAATTAATGATTTGATAAATACTTTAATATAAAA AGTATTTATCAG

TATAATATCTAATCAATATAAATATTCAATAATTAATAAAATTTTAAGTTAGATATT AAATATTATATT

AATATTAGAATAGTATAATAAATATTAAATATTAGAAATATCTAATAATTATTACAT ATAAGGTATAT

AGTATTTCAATTATATTAGTATTAATAAGTTTTATCAATATAATTTAAATAACAATT CTATATACTGAA

TGAATAAAAATAATTATTCAGAGAGGAGAGTATACTTTTGTTATATATCAGTGACCT AAAGAAGTATA

GATTATATAAAGGTAATAAGCTTAATGGTATTAATAAGTTAAGTGAAAATAAAGATC CAAATAAAGGT

CAATTAATATTACATTTAGGAAATAATGATACAGATATTATCAGTTTCTTTAATTCA AGAATATTTAAG

AATAATCTATTCAAAAGTTATTCTACAGCTAGAAGATATAGAACTAATAATAAACGA AAAATGTATAT

TAAAGATCTTAAAGAACATTTTGCAAAGATAAAGAAAGAAACAAAAGTTACATTATT TACTAAAGTAA

ATTATAAACAGTTTAAGGGTAATAACTTAGTATATGATATTACAGATCAATATAATA TTGAAATTGAA

TCAATTAATAATAAAAAGAATGGTTTAATGGTTTCTAATAACTTTATAAAGTTATTA GAAAAATCTCTG

TTGGAAGAATATGATGATACAGTATTATTAATTAATATGAATACATTGAACGTAGAT ATGGATGATAT

ATTCAATATTACTAAGTCTACTCATCCACTAACAGTTATTGATTTTATTATTAAAAA GAAATTGGATAT

TAGTAACTTAATTGACAAGAATATAACAATTGTTGTATTTAATCCTAATAACAGATT ATTTTATAGTTA

TCCATTAACTACAGAATTATATCCTAAAAGACAGATCATCAATCAAAGATCTAAATC ACTAATTAATTT

GGAAGTTAATGAAATTGAAAGCAATGATGAGATGAGTAATATTCCAGACATTAATGA TATTGATGATG

CTAAAAGACAACTAGGTAATAATATGAGGTTAGGTCGATTAAGGTCTAGAAGTAAGA TACCTGTTAGT

ATAGACAATTCTGAAGTAAGTAATAATTCTTCACAAGAAGACTCAATAACAACTAAA AAATTAGATGA

TATTGATAAAGCTAATGAAATAAATGATAAGGTTGAAGAAATTATTACCCTTACTAG TGATAATACTT

TATTATCTTCAGAAGCTAAAAAACAATTATATACAATAGCTCAAGATGAAATTAAAA ATAATAAAGAT

TTAGTTAAGATGGATAGTGCTAAAGTTGTCTCTATTCTTAATCGTAATGAAGAATTC AATAGAATAGTT

TCAATGTCTTATAGATCATTTAATATTGGTGGATCGAACGCAAAAGAGCTTGCAAGA ACAGCAGCACT

ACAAAAAAGACAGAATGAAATCCTTAATGATAAAAATATTTCGAATGTATTAGCTCA TGCAAATGATA

AAATGATTGATAAAGGAATTATTAAATCAAATAATATTAATGATGAAACATTATCAG AACTTTCTGTA

AACTCTTTTGATAAGAGTTACATTGAGAAACAATTTAATGCCGATATTATTAATGTG TTAAAATCATTT

AACGATAATGAGGATATTAGCGTATTCATCTCAGACATATCTTCTGAAGACTCTTCA GACTTTCAGACA

AAGAAAACTACATTAAACGTTAAGCTTAAAGATACTAAAGGCATTAATCATAAACTA TCATTAGATAT

TCCTAAGATATATAACGGTAGATATATGATGGTTAACGGTAGTAAAAAAATACTAAC AAAACAGTTAC

TGTTAAAACCTGTAGTAAAAACTGCACCGGACACAGTACAAATAACTACTAACTACA ATAAAATGTTT

GTTAAGAGATTTGGTAGAAAAGATACTCCAATGTTAGCTTCTATCAAAGAAATCTTT AATAAATTTAA AATTGAAGATCATCTTCTTTCTGGTAAAAACATTAAATATTCTTTAGGTAATTCATTATT AGTTAACTC

AAAATATCTAACTTCAGTAGAATACAATAATATTTCTAATTATTTACTAAGCTTTAG TTCTGGTAAAGA

TTATTACAATTTTAACCAAAAGTTATTATTAGAATTCATTGATAATGATGATAAACT TAATTCACTAGA

ATATGATTCTACGTTATATTTCCCAGTAGGATATACTTCAGATAAAAGTAAACTTAT CTTAGCAAATTT

TAAAGATTATCACGTTTATTATAAAGGTGCAACTAATAATTATGAATTTGTAGAAGA AAGTTTAAGTA

GAATGATATTACTAAATATTTTGATGAATGTTGATGATGAGGTTGCTAAGTTTATTG ATAAGGGAATTA

AAGCAAATGATAAACTAACATATACACGAGTAAATATCATTAATAAAACAATTCCTC TAATAATATTA

TTGTCATATGAGAATGGATTAATCAATACATTGAATCGATATAATATTGACTTTGAA GTATTAGATTCC

AATCCTAAACTAAAGATTACTGATAATAAAGTTAAACTTAAATTTAAGGATAAATAT TTGGTATATGA

TAATACACTAATAAGAAATTCATTATTATTGTCAGGTCTTCATATAATGGATATTAA TGAATATAACTT

AGATGAAATGGAAACCAAAGAACCATATTTAGATTTATTCCAAGAATTGTTTAATAG TCGGAATGTAG

CTAAAGGTATTCATAATGCATTATCTCTCGCTATTGATCCTATCACCAAAGAAGTTT TAGAAGATCTGG

GATTACCAACTAATATATTTGATGTCTTATTGTATTCAAATACATTATTAGAAGATA TGTCTTATAATA

CTCCTAATGATATGAATGTCTATCGAATTCGTGGGGCAGAGCAAATCTCTGGTATGA TTTATAAGATA

ATTGCTGAATCATACAAGAACTATAAGGATTCTCTAAATTCAAGAAATAGTGCTACT AGAATTACTGT

ACCAAAGGACATTCTTATAAAGACTCTTATGGAGAGTCATACGGTAGAGGAAAATTC TGAATTAAACC

CAACATTAGAAGTTGAAGTTAGTGGTAAAGTATCTTATAAAGGACCAAATGGTCTTA ACTTAAGTCAA

GGTTATACTCCTGCAGTTCGTTCATATGACCGTTCTATGAAAGGAATATTGTCGATG ATATCACCAGAC

AGTAGTAAGATTGGTGAAGTTCGTCAATTAAGTTATAATCCTGCAATAGTTAGTACT CGTGGATATTTA

GATGTAGATGCTTTAAACGGTAATGAATCTACAAGCCTATATTCTCCTTCTGAACTT TTAAATAACTTT

ACAAGCTTACATGCTGATCCACCACGTATATCTATGCAAGTAACTCAACAAAAACAT TTACTAACAAC

AAGAGTCAATAGTAAACCGCTTATCGGTACTGGTGTAGAAAAATCATTAGCATATCA AATATCTGATA

CTTTTGCTACTAAAGCTAAATATGATGGTAAAGTAGATAAGATAGATACTGTTAATA ATTTAATGATG

GTTTCTTACGATAACGGTAAAAAAGATATCATTGATATTGGAGTTGTAATGAATAAA AACTCCGGTGG

AGGATTCTTTTTAGCACAATCTAAAGATATTATGTTTAAAGAAGGTCAAAAGTTCAA GAATGGAGAAA

TTCTTGCAAAGAATCCTAACTTCTTTATTGGTGATAAGCAAGGTGAAATATCATATG CTATTGGTAAAC

TTTCTAAAGTAGCTTTAGCTCCATTAGACGGAACTTATGAAGATAGTTCTATGATAT CATCATCTATGT

CAGAGGATATGACTTCTAAAATTACAATGAAAAAAGATTTAGTGTTAGGTACTTCGG CAAACTTATCT

TATATTGTAAAAGAAGGTCAAAACGTTAAGACTGGAGATTCATTAGCTGTATTTGAA AATGAATTTGA

TGATGATTCTATAAATCAGCTATTAAATACTATTGGTGATAAATTTGAAGAAGAAAT CCAAGAAATAT

CTAATAAAGTTGTAAAATCAAAGTATACTGGGGTAGTCCAGAAGATTAATATTTATT ATAATCGAGAG

ATTGATGAATTTTCTTCTTCATTACAAAAGTTAATTAAAGCTTATATTTCTAAATAT GAAAAGAAAAAT

AAGATAATCTCAGATTATATGAAAGATAGCGATATTGATATATCATATGATATGAAT ATTCCTAGTATT

ACTAAAATGGATTCAGATAAGATTAAGGGTAATGATGTAGATGGATTATTAATTGAA TTCTATATTGA

ATATGAGGATAATTTAAGTACTGGTGATAAAGTAACATATTATACGGCACTTAAAAC GGTTATATCTG

ACGTATTCCCAGAAGGTGAAGAACCTTTTGCAGAATCAGACCCAGAAGAACATATTG AAGCAGTATTG

TCTCCATTATCTGTTATTTCTCGTATGACTCAAGACGTTTATCTAACATTATATACT AACAAAGCATTAA TCAATCTGAAAAAACAAATTGGTGAAATGTTAAAATAACTCACTCTTGAGAGAAACATAT TAATATTA

TAGATGTGAAGGTTGCTTTGTGCAGCTTTCGCATCTATAATTTCTATCAAGAAAGTT GGTGAAACTAGT

GGGTAAGTTAGTATCAAATAATAATAACGGGAATAATGTAAGTCCTATAGAAAAAGA TATTGTAAATA

ACTATATAGGTAGTTATATTGAAGGTACTAGTGCATATAGTAAACTATTAGAAAATG CTCCCAATTTTG

TTACCTATTACTCTAAAAATACTAGATCATCTAATGAAGATCCGGGTCTTGGAGGAA CTGTTGAATAC

GTAGGTTCAGAATCTTCACTATTATATAACAAAATAAAGAATTTTCCAGTATTTTCC GTTAATGAAATA

AATCCTACTTTTAATTTTGAAGAAGGCGTAGGACTGGATACTGAATTAGAAAGTCAA GCAATAGTACT

ACCTAAAACTATTATACCTTTACCTGATGATTATTTGACATTTTCATATCATGAAAA AGGATATGAGTA

TTTTAAGACATATCGAATTAATAATGTTTCTACTTCTTCAATAGGTAGTAACACCTA CTATTCAATAAC

TTTTATTAATGATCCTATAGATATAAGGATTCTTGAAGAAAGACAAGTAGATAAAAC TTATAGATTTGT

TTATGAAAATGTAGGTACTACTGATAAAGTAATTATAGAAGAAGATGACATATTATT AATTGATAAAA

TTGAAAAGATATGTGGAGATATTAATGAAAGATATATTAATAATTTCTACAATTCAC AGTTAGGTATTT

TATTATACGAAAATCTAGATGAAAGTTTATTATATAGTCCTAATCTTCATTATTTTA TAAATAAGAATC

AGGTATTTATAAATAATCGAACTTTCATGAGAAACGTATATATAGAAGATATAACAA AAGTGAAGCTG

AAAGATTATAACAAATCTTTATTTAGCATTATTGATAATGGTTATAATAACATTAAT ATGTCTTATCAA

TATATAACTAGGGTTTTGGAAAATAATATTCTAAAGAAAACTAGGGGTCTTTATGTT GAAGATTTAGA

AATTATTGGATCTAGTTGTAATATTAAAATTCCGAGAACTACGATTCATAATTATTT TTCAGTAGATAT

TAATGATTTGATAAATAACTATGATGGCGTAGACTCGTTAAATGGTATAGATGCGAT AACATCAATTA

TAACAATTTATTTAGAACAACCAGAACAATTAAGTATTAATACGTTATTTAATTTAG TTTCTAAATTAA

ATTATGATGACTATTCAATCAGTAATTATTTCTTTATACCATGCGTATTATCCATTA TAAATATAATTAC

TAATAAAAATTACTATACATTCTGAAGAAGTATAGAACTGAGAGGAACGTGAATATA AATGTTTAAGA

AAATAGAAGAAAAAATCCATCAAAGAAATATGGAAGTTGAAGCTAGTAAAATTGTAA GTGAAGAATT

AGAAGTTGTTGAACCAGAAGAAGAAAAAATTATTGCAGTACCTAATACTTCTGAAAA CAATGAAGTTT

TGGGTAATCCAGAACAAGATCCTGAAATTGGTCAATTTATCGATAGCACTGATGAAT ACGATGATGAA

GAAGATGCATTGATTGATGCTTTAGAAGATAAAAATGACGATGAAGGTTTAGACGGT ATTGTTGATAA

AGATAATGAAGAAAAACCTGTAGAAACTTCTGAAGTTACATTTAGTGAATCTAAAGA TGATAAAAAA

GAAGATAAGAAAGATGAGGACGAAAAAGAAGATTCTGAAGATGAAGACAACGATGAA TCTGAGGAA

GCTGAAGAAGAAGATGGTGATGATGAGTCTGAACTTGAAGAAGGAATCAGTTCCATG TTCTCTGGAAT

TTTTGACATCAATGAAGAAATTGAAGATGATACTAATAATATTTTAAATACACTAAT CAGCGAAGAAG

AAGATATCTTTATTAAAGATGAAGAAGACGAAAAAGATGATGAACCTATTGAAATTG ATTTTATTGGT

GATGATGAAAAAGATCAAGAAGATAAAGAAATCGAAGAATCTGATACTGATTATCTT AAAAAAGAAT

ATCTAGGTGAAACAATACTTAATAAAATCTTCGACAAATAATACTGTTAACATAATA TTATTAAGGGT

ATATAAAATATAAATTATATAAAGGATGTGTATTTCAAAATGCCAAAAGTTGTTATA AAAGATAATAA

ATTTGTATTTGGTTTAGGTAAAGGACCATTTAATAATCCAGTTGAGATTAGTGATGA ACTTTTACGTAA

ATTAAAAATCTCTGGATATACGGTAATTGAAGTAAATGATCGTCATATCGTATATGA AACTCCAAATA

ATGAAGAAAAAGCTGAAGAAGTTAAAGAAGATCCTAAAGAAGAACTACACCAAGAAG AAGAGTCTG

ATGAATCCGTAGAAGCTACTGCAACTGAAGAAGAAAATAAAGACGAAGAACATCAAG AAGAATCTAA TGAAGAAAAAACCGAATCATCTAAAGAATCTGATAACGAAAAAGTTGAAGATGATAGTGA TGAAGAA

GATTTCAAATCAATGAAGGTTGATGAACTTAAAGAAATTCTAGAAGAACGTGGAATT GAATTCAAAGC

TAATGATACTAAAAAAGTTCTCCTTTCAAAATTAGGTGTAAGTGAATAATATTTTTA TATTATATTGAT

AGGTCTACTTGTTGAAATTATAGCAAGTAGACCTATTTTTTTCGATTATTATAAGTT AGATAAGAGGTG

TTTATGTGTGCCAAAAGTAATTATATTAAATAATAAATATATACCAGATATTGGTAG TGGTCCAATACT

AGAACCAATTGAAATCAGTAATGAAAAATACCATTATCTAATAGATAATGGTTTTAA TATATATCAGA

TAGACGATAATGAAGATATTATGATTGATCCATCCATAACTACCATATTGAAAGGTA AAGTTAAGTCA

GTATATGGAATGTTTCATGCAGATCAGAAAAAACTTGATTCACTATTAATGTTTAAT AGAACAAGCAT

ATCTTCATTAAAAAATGTTAATACTAAGAGTATTACAGAAAATAATAATATAATATA TTGGAAATCAA

TAGATACCGATATTGCATATGTAAATTCTGACGGTTATATTGCTGCAAAAGAAAATG GTTACACAATA

GTTACTGGTTTTGATTCAAATAATACGCTTAAAGCAATAATGTTCATAACGGTAATA CCTAAACTTCCA

ATATTACCCAATGATATTAATGTTAATTTAGAAAGCTATATGGAACTTAATAGATAT GCAGAATTTCAA

TACTTAGTTGAATTACTTCCTAGCGAAGTAGATAATAATAAAGTAAGTATTACATCA AATAATATACA

AATTGCAACTATTGATGAAAAGAATAAAAGAATTATTGCTGAAGAACCTGGATATGC TGTTATTAATG

TTAAGAGTGCAGAAAACCCTGAAGTATCTCATAGTACGTTGCTAAAAGTTTTTCCTA ATGATGATAGG

AATAATCCTTCTAATATAAATGTAAATATTCCGGACGAGATTACAATTAAGGTTGGA GAGGAAATTCC

CTTTGAAGTAAAAATTACTCCTGAGTCGGCTAATAATCTAGGATATATGTCTTTCTC ATCAAAAGTTGG

AATTGTATCTTTATTAGATAATAACCATATTCTTGGTAATAGTATTGGCGTAGCAAC CATAACTATTGT

ATCGAATAAAATATCATCATTATATAAAGAAATACGAGTTAATGTTGAAGCACCAGA CCCTAATGATA

TTATTGTAAATTTAACTGAAGTATCTATTGAGAAAGGTCAGACTAGAGGGTTTAATG TAACAGTTCTTC

CAATATCAGCTAATGACAGAACTTACAGTAATAGTTCTTTAAATGAAAATATTGCGA CTGTAACTCAG

AATAATATTATTACCGGAGTTAATATTGGGGACACAAAAGTAAGAATAACATCTAAT AAAAAGCCTGA

ATTATTTAGGGATATTATCGTGCATGTTACTCCACCAAGCCCTAAAGATATTATGAC TGATCTTCCAGA

CGAGATTACAATTACTGATACCGAAACTAGAAATTTTACAGTTCAAATTCTTCCTGA AGATACATTTAA

CAACAAATATGATATGGAAGTAACAATTCCGGATATTATTGATCTTGATAAAGAAAA TTTATCATTTA

AAGGTAAAAAGATAGGTGTAACTAATTTAAGAATTTTTTCACAGTATAACCATGATA TTTTTAAAAAT

GTTAAAATTAATGTAGTACCAAGTCCATTACCTGATCCGACATCTTTTAAAGTTATT CGTAGAGATACT

GGGGAAGAATTAAAAAATGGAGATACTGTACCTAGTAATAAAGATATACTTTTTGAT GTTATAGTTTT

ACCAGAAAATGCCAATGATAAAAGTTATATAGTATCATCTTCAGACGTAACGATTGC AAAAGTTAACT

TAAATTCTATAATAGGAGTTTCTCCTGGTCAAGTTAATATTAGAATAACATTAAACA AAGTTTCAACAA

TATTTAAAGTATTTCAACTTAATATTGAAGAACCTGTTCCTACATTAATTGATATTG ATGTACCAAGCA

ATATTACTGTACAAACTATGCAAACACGTAATTTCACTGCAACTATATATCCTGAAA ATACTCCATACC

AAAATTTCTTAACATCTGTTGAAAATCCTGATATAGTAACTATTTTAGATAATACAA ATCCAAAAATAC

GTACGATTAAAGGAATAAAACAAGGTGTAACTAAGGTTAAAGTGTATTCCGAATTTG ATCCAACAATA

TTTAAAGAAATTAACGTTACAGTAGTTAATCCTAATCCTAGTTCAATAGAAGTTTCT CCAAGAAGTATT

TCAATGTTATTAAATGAAACTAAAGAATTGGATATTAATGTATTGCCAGAATATGCT AATGATAGAAC

ATACACTATTAAACAAACAGGCTTAGGTATGGTTTCTATTAATGGAAATAAGATTAC TGGTGTGTTAA AAGGAAATGTAAGATTAGATATTATATCTAACAAAGTAAGTTCTCTTGGAACTACGGTAT ATGTTACT

GTTGATAATCCTGACCCTGAAGATATGATTGTCGATATACCTGACGAGATCGATATC AATGTAGATGA

AAGAAGAAATTTTGGTATAACATTTGTTCCAGAAATAGTTAGTGATGATTCTATTAT TATAACATCATC

TAATTCTAGTATTGCTATAGGTAGTGCTGTACAAAAATTTATTAATGGAGTTTCTGT TGGTACTGCAAC

ATTAACTATTAGATCTAATAAAGTAGCTACTTTATTTAAAGAAGTTATCGTAAATGT TCATGAAGATAG

ACCTGACCCAACAAGTATCAATGTTGGAACTAATCCGCTTACTTTAGAATTAGGTAC TACAACTCCAAT

AAATATTGCATATGAACCAGAAATTAATAGTGGTGGTAAAATAATTGATGATTATTC CACATCAAACA

CTATTATTAGAATGGATCAATTTAAAAATTCAATACAAGCTATTCGACTAGGATCTA CTAGTATTAAAT

ATACTTCTGAAAGATTTCCAAATATTACAAATACGTCTAAATATTACAGTTATTCCT CCTAGACCAAAA

AGTATTAGTGATAACTTTTCATATAATAATTCTTTAAATGTTAATGAAGCAACAAAT AAATCGTTAATT

GTTAGCTTTTTACCAAGCACGGCGGTAAACATTGGATACAATGTAGTTATTGATGAT CCAACTGTTTTA

TTATTTAATACAAACTCTAAGAAATTTGAAGCATTAAAAGAAGGAGAGACTATCGTT AAGGTGGTATC

TACTGATAATTCTTCTCTATTTGTAGAACATAAATTTAAAGTTAATAAAAATATTAT TATCGATGACGG

TGGTAACGGTAAAGATGATGATGGTAATGAAGTTATAGTTCCAAAATCAATAACGTC AGATATAGTCA

CTGAAATGATAGTCGATAAGAACTATCGGGTAAACGTAACAGTTTTACCAGATAATG CTATTGATAAA

GGTTTTGAAGTTATAACTAGCGATAATAATGCGTTTAATATAGTTCAAAACAGTGGA TCATATTTTACT

ATTAAATCATTGGTTTCTGGAATGTATAATATTACGTTGCAATCTACATTAAATCCT AATATAAGCGTA

TCTTATGATATCGTGTCAGGCACTGAAGATGAATTACATCCAATCTTACCAGAAACA ATAAATATTAT

AAATGCTACTGATGAAATGACTGTAGATGAAGGTACATCTATGAATTTAGATATACA AGTTCTACCAG

AAAATTCAACTAATAAAAATGTAACTGGTTACAGTAGTAATGAAGAATTAGCAACTA TACCTAATAAT

AAAACTATAAGTTTTATTAAAGAAGGTTCAGTAGACATTACAATTACATCAAATAAA GTACCTACATT

AAGTAAAACAATTCACTTTATTATTAAAAAACCCGACCCTAAGAGAATTGAAATTAA TGCACCCAACG

CAGTAACTTTAAATATCGGTGAGTCTAAAGAATATCTGATAAGTGTAATTCCTGAAA ATAGTATTGAT

AAAGAATATATTTCAGAAACACTAGATTCTAGTATTGTTACTACTAATGGAAAAAAT ATTATTAAAGC

GGTTAAAGAAGGAAACACTACAATTGTGTTTAGGTCTAAAACTTTTCCAGATATATT TACACGACTTA

ATGTTATTGTTCTTCCTCCTGAACCGAATGAAATAATTGTATCTCCATCCAATGAAA CAATTAATATGA

TTAAGCTTGATGAATTAGTATTTGATGTAACGATTAATCCTTCAAACGCAATCGATT TAACATATAAGA

TTGAGTCAAGTGATACTAATATTGTAAAAATTAAAAATCAAGATACAGTGGTTGCAG TAAATCCCGGA

GAAGCAAACGTGACTATATCGTCTAGACAGAATGCTAATCTAAAAGTTATTAAAAAG ATTATTGTAAC

TGCGCCTGACCCAGAATCTATAGATGTTATTGGTTTTGGACCAGACGAAACAATGAT TACAAATTCAA

CAACTAAGTCCGTTAATTTTATAGTCAATCCGGCTAATGCTAAAGTATCTAACTTTA CAGTAGTATCTT

CTAGTGATTCGGTACAAATTAATATTCCGGATCAAACAAAATATGGATTTACTGTAA AACCTGTTAAA

GAGGGTAATGCAATTATCACTATCCAATTATCATCATTCCCAGATATTATTTACAAT ATTAATGTAAGG

GTGAATAACCCTGATCCTGAAAGCATAACTGCAGGGATAACTAATCCTCCAAATATG CCTTCTGGAAA

TATTCCAGGAAAAGGAATTGCTATAGGAGAGAAGGTTGTATTAAATGCTAAGATACT ACCTGAATATG

CTAATGATATAACTTACTCAATTAGTAGTAGCGATAATGATGTCTTTGAGGTTCGAG ATGATGGAATTT

ATGCATTAAAAGCCGGAACATCTAAAGTTAGGGTATTCTCTAATAAAGTTCCAACAA TATTTAAAGAA TTTGATTTAGAATGTCTAGGTAATAATGTTAGTGATATTGAACTGGATATTCAGTCACCA TTCAATATG

GTCGTTGGTAATACGAAACAAATAAGTATAAATATTCTTCCTACTGATGCTATTGAT AAGAGGTATCA

GCTTAAAACAGATGACGCTAATATTGTATCGGTATTAGATAATAATACAATACGAGC TATATCTCTCTG

GGGTAAATGGTGAAGGATTTACGAATATACGAATAATATCTTTACGTAATAATTCTG TGGTTAAAGTA

ATACGAGTTAATGTAGAAAACTTAACGCCTCAAAGTATTGATCTTGTTCCATCTGGA CCCATAGAAAT

ATATTCATTAACATCAACTACATTTAATGCATATGTAAGACCAGACACTGTAATTGA TAGGGATACGG

TAGTTAGTAGTTCAGACATTTCAATAGCTACGGTTCAACAATCATATATAACTGAAG GTGGCATAAAA

ATTACTAGAGTTACAGTAAATGCACTTAAATCTGGAAATGTTAATATTCGTGTATCA TCTAATAATTAT

AGAAATATTTTTAAGATGATTAATATAAATATTATTGACCCAGATCCGGAATCAATT ACTGTAACTCCA

TTAACAATAAATATGGCTCAAGATACATCTACTAATTTTAATGTAAATATTCTTCCA GAGAATGCTAAT

GATAGAACATTTAATACTGAGATTGCAGATCCTACAATTGTTTCTGTTAATGGAAAT ACAATTACTGGT

CTTAAAACAGGAACGACTACAGTTAAAGTATCTTCAAATAAAATACCATCATTAAAT AAGACAATCAC

AGTCAATGTGAGTCTTCCTAATGTAAATAAAATTGAGATTACTACTGCATTAGTTGC GGGAACAGTTA

ATACTGTATATGAGGGCGAGTCTTATCCATTTCTTATTAAGTTATTGCCAGAAGTTG CTGCAGATAAAT

CATTTACGATAAAATATTCTGCTAATGCTGATATGTCTGGTACTGCTGATTACTCAT TTAATTTTGGATA

TCGTAATGATTCATTAAATCCATCACTATATATATCAGCTACAAGTTCATCTAGATA TGTTCCACCTTTT

GTTAGATATATTCAAGTGGTTTCAGCTAATGGAATTACCTCGGATATATATGGTCTA AGTGTTGTACTT

AAACCTATATATAAAATGGATAGTACATTTACATTTTATAATGATCAGTAAGCTTCT GCTAAAACTACT

ATATCTTTTGATAGTACTAATCCTAATTCTGAAAATTATGTAATTAATGCCTATGCC GGAACAACAGCT

AGAGACCCTAATATTAATACTGTTAATTTATATCCTCTTGAAGCAAAAGATACAAAT TTAACAGTTACT

ATAAGTGATCCTACAAAAGCATCATATAATAGTACAACTAAGACTTTTACAGCTCTT CAATATGATACT

GAAACTACTGCAAAGATTGCATCCACAACTAGCCCTGATGTATTTGTAATTGTTAAG ATTAAATGTATG

AGATCTAGAATAACGTCTGTACAAGTTACAGGTCAGAATGGATTAAGATATAGTACT GGCGATGTCTT

TGGAATAGTAGTAACAACTGGTCCAGAAGGTGCTATTGATACAAATGATTATACATT ATCTTCAAGTA

ATGATACTATTATATCAATAAATAATGAAACTAGAACTGGAGTTGCTTTAAAGGCAG GTTCATCAACT

ATTACCGCATTATTTAATAAAGCCGGCGTATCAAATAGTGCTAGATTTACTATATCT GACGTACTTCCC

ACTTCAGTAGGTATTACTGACCCTCCAGGAGGTTCTGAGCTAATTATTGGAAGATCC TATCCGATAACT

CCAAGTGTATTGCCGACTAATACAACTAATAAAGCGGTAACCTATTCTGGAAATAAT TCAAGTTATTT

AACATTGTCTAAAATAAATAATATTGATTATATTAATGTGTTGGGTAAAATTGCAAC AAATACACCTAT

AACTATTCGATCAGTTGCTAGTACGGGAATTTACAGTACAGTTCAATATAAGACTGC GTATGAATACC

CAACAAGCATTGATATATCCAAAATTAATGACTCATATAATTTAACTGAAACAATTG ACTTATCTACTT

TGATAAATATAATTCCATCAAATACCGATAATGATAATAATTATACAATAACAACTC AAGATACCGAT

AAAATAAATATTGATGGTAAGAAATTAACATTTATTAAAGATGGTAGTGCAACTATT ACAGTAACTCA

TAATAGAAATAATATTTCCGTTAATAAATTGATTAATATTGTATATAATGATTCAAT TAAACCGAATAT

TGTATTTACTACTTCAAATATTATCATAAATAATAATGAATTTGATATTAAAAATAA TATTACTAAAGA

TTTAACACTAGATGAATACCTCATTACTGGTGATCTTAATGGTTGGAGATATAATGG CAATAAGAAGT

TTTCAGATAGTGGAGATTTTCAAATTAAATTTAATTATCCTATTAATATGCTTGAAT TTGAAAGTATTA ATGATCAATTTTCAAGTGAATTTATGTATAATTTAAATAATCCGGATTCTAAAGTTGATC CACCCCAAT

ATGTTGACCTTGATAGGGGTAGTGATTTGATTAATGATCGATTATTTAGTATATTAG ATACGTATACCA

TTTCTTCATATTATAATAAACGAAGAAGTACTAGTGGTAATGAAAGTCAATCATATA TTGTAAGCGCTT

CACCAGTAATAAATAATATATCTCCTGCAGGAGAATATTTTTATAAAGTCTATGTAA AGAATGATCCT

AATAATTATATTATTATTAGAATTAATATCGGTATTCATGGATCAAAACAATCCAGT AATTTGATATAT

AATGGATATCCTACTCTCATTAGTCCAGTATCAATATCTACTGATGATAATATAAAC TATGAACTTAAA

GTACAGCTGTATTTAAGATCTAAGTGGTTGAGTGGGGACAAATCACCTTTATTATTT AATAATGAGTTA

ATTACTCATCGATTAATGCTTGATTCTTCATATAATAATAAAATAAATATTAATGGT ATTGAATATAAT

AACATTAGTGATTTTATTGAAATTGATAATAGAATTATTAATCGAATAAGTAGACTA GGTGTAAATCG

TGTAAATACTATTACCAATACTGTCGCATCTATTGATAGTGTGGTCGCAGCATATCC GGACAGGGTAA

GTTATTTTATTAAAAGAAATCCTACTAAAAATGAAGAATTTAGTATGGATATAAGAT TAGTAAGTATT

GAGGATTCGAATATCAAAATTCCAGTAACTTATACATTCACTACAATTAATAAATAA TTCTTTCAAAGA

AGCATATGATAAGATTCTTGAAAAGAAGATTAAAAAAAAAAAAAAAATAAATCTCCC ATAACCTATT

AATTTAGGTTATGGGAGATTTTATGATTATTTATTAAACAGATCATCAATATTATTA GTATCGATATCT

TCTTGAGTTTCTTCCTCATCATCTTCATCTAACGGTACAAAATTGATAACTGGTTTA TATCCTAATGCCT

TTGCAATATCTGATAGACTGGAATAAGATGTCGCACCTTTTTTCCGTAGTCTGTAAA AGATATTAGAAG

CTCTTCCTTCATTATTAGGATTATCAAGATCAAACTTTTCAAAGAATTCTTCAAATG TTTTACCTTTTTC

ACCCTGCTCATTAATGAATTCTGCAGTAATTAATGCTAATTCTGTTTGATTTTCAAT AGAATCCACATC

AATATGCAATGGACCAGTTAATTTCTTTCGTTTAGATTTCTCAGAAGGATCTTTAGA AGCCTTGATCAT

ACTATCTTTCTTATCTAATTTATCCATATTTACATTATTTAGTTTTGAAAATAGATC ATCGGACACGAGA

ATTTCACCTCATTTATTATTCATATTAGAAATCCATATCATCATTAGAAATTTCTTC AGAAGCACCAAT

CTCAGTTGATTTTGCAATTAATGATTTAAGATCTTTTGATCCACCACTAGCTTGGAT AATTTCTGTATCC

ACATCTTCTGTTTGTTTATCTGCAACTTTTTTCTAGGATGATTTAAAGTTACTACCA CTATTATTACTGT

TATTAAATGTAGAACTTACATTTTTAGGTTCAGTGGTTGTATCATTTTGTGATAGAT TGTTATCATAAG

GATGTTGAGTTGCGTTTGGATTCTTTCTAGTTACTCGATTACTATTGAATCCACCAC TTGTGTTTCCTGA

ACGATTGAATGGAGTTGTTGATGTAGGTCTATTAAATCCACCAGTGTTTGGACGTTG ACTAAATGAAC

CACTATTATTAGATTGACCTTGAGAATAATTTCCTCCGCCCAAAATATTAATAACGT GATCTAATTTAT

TTTCTACAGTATATAATTTCGCTTGAATTTTCTGGAACTCTTGTAGAATATAAAGAT CAATATTATTAAT

ACAATCAATCATATTGAATAATTGTAGTGTAGTTAGTTCTACTGAATATTCATCGCC ATTTACGCATAA

AATAAATCCTGGATAAGTAGTATCATCATTACGATGAATGATTGAAGGATAGATTAA TAATTTTTTACC

TTGACCACCAAACTCTGGAGAGAACCATTGTGGTAATTCTGGAAGATCCCATACACG ATTACCTGAAT

TATTACCTTCAATAATTTCATTAGCAACTTGGTTCATATATGATTTTAATGTTTCAT GATGAGCCTGACT

AACTACAACATTCTCACGAACGCTTTGATTAGTTTCAGGATTAAATCGACTATAATC AAAACGTAAAA

ACACCGTTGCGCTGTTTTGAATACTAGTTAACGTTTGAACATCGGAATATCGATCTG AAGTGTATTCTC

TTGCATATTCAGCATCCCTACGTTTATCATTAGTTGATGTTTTATTACCTAGTAATA AAGAACTTTCTAG

TTTAAAATTGAAAGCACTAAATAGCGTTAGACCATGAGATTCTACTGGATTAAAATT TGACAAAATAT

GATTCCTCCTAATAATTTTATATATTACAATAATATAATATATGATTATAATTTATT TTAAATGATTATT CATTTGTATCTTGATTTAATGATAATGCAGTAAGTCTGGAAAGCTTACTAACAAACTGAC TTCGTATAA

TTGATGAGTACAATGCTTCTTCAGGAACATTAAACATTTCACCAATCTTACTGATAC TGTCACCTGAAG

TATAATCTAAGAATTGATATACACTAAAAATATTGATAGGTTCAGGAATGATATATT CTGGAATTACT

GGAATTTTATTTTTAAATAAGAAAGCTTTATCTAAGAAATGAATCCAATCTATTGGA TTATCTACCCAA

AAAAGTATTTTATTTTTTCCTGAATTAGAAAGCTCTAATAACAATGATTCAATATTA TTGTATATTGTTG

CATCTTCATCTTTCATAATTCTAATATTTTTGTTAGCATCATAAGTATAAATCTTTT CAACATTATTCGC

TAGTTGATTATTATATACTTTCATACTATCTTCTTGGGATATAGCTGTAGCAATATC GTAATTTGTAAAT

TCATAATAGTAATTAGATATTACACCTTCTGCTTCTTCTACACCCAAACACATATTC ATGATGTTAGAT

GACGTACTAGACCCATCTAACATACATGATAAGTAAATATTTACAATCTTAGTTCTT TCCATATTTTAC

CCATCCTTATTTAATTCTTTTTGTTTTTTCATTTCTTTATTATAGAATATATCATGA GTTAATAAAAATTT

GAAATTAAGTTCAGAATTAATACTATTGATAATATCTTTAATACTTTTATTAATAAC TGCAGGGTTTGT

TAAATCTTCAAGAATTTTCTTTTCCCTAATATCATTATTAATAGTTAAAGACATATC AAGTAGATCGTTT

TTAATTTTATGATATTTTTCAAATTTAAGTTTACGATGTCTATAGAAAAAACCATCA CTATTATTTTCAC

TATACATCTTTAAGAATGATGCATATTTATTAAATAAGTCTTCCCTTTGAATTTTAA TTTCACCTTTTTG

GAGTTCTAAAATTTCAATAGACCTTTTAATATGGTTATTAATTTTTCTAAGTTGAGT TAATTCAATATCA

ATAATCTCTGTAACAAGATCAAAATTTACAATTCCGATAATATTACCGTCAATATTA ATATTAAATCTA

AGAATATTAAAGTCTTCTGAAATTTTAGCACCAATTAATGAAAAGATATCTTCATCA TACTGTCCAGTA

TTAACATTCTTTGTTAAAGAATATATAAAATCTTTCTTAATACGATTCACAATCGTA TTAAAGATATTTT

TACTAGCGATTAATTCTTCAATGAATTTTGAAGGATTTGTTTCTGAGAGGGAATAAC GATCGTTAGATG

CATACAAAATTTTCACCACTTTCCGCTATATAATTTCCAATTTAGATTCAATAATTT CTTTACATCTTTT

ACGATAAATTTTCTTTCTTTTAGTTAATTGACGTTTACATTCATCAAAACCTGTATC AATGACATCAAA

GTATAGACATTCTTTATTTTTTACCTTACGTAAACGACCCATAATTTGTATCAACCC TTCTTCAGAACCA

GAAGGTACAGTATTTACTAATACTCGTAAAGATTGTTCATCTAAACCTTTACCGAAA GATTTATCCGTA

GTAACAATAATATCTTTTTCAAACGCAGTAGATTTTTCATCTTTAGGAACGTCTGAA TAAAATCTACTT

ACCGATATATCCCACTTATTATTTTCAATTTCTACTAAGAAATCTTGGTAGAAAGCA TTAACCATAATC

TTATTTTTAAATAAGATTGCAGTCTTTCTTTTATTCTTACCTTTATCAAAGATAATA TCGAAGATAATCT

GATAAATATAGTTATAATATTCATCATGCTTTTTATCAATAATATACTGAGAATAGC TTGGTACATTAA

ATCCATAACCTTTAGATTTCTTTCTAATTTCAACTAAATCTTCATTACTAGGTTTAG TATCTATTTTACA

AATGATTGTTCTAATGTATCTATCACTATCACTAACTACAGTAGAGAATTTTGGAAC GTTCATATACAT

ATTCTGATAAACTTTATTTTCAATAGGATTAGATCTACTAGGAGTCGCAGTTAAATA TAATGATGGACA

GTCATAAGTAGAATCAATATTAAATACAGAAATATATTCAACGTGAGCTTCATCATA AACTTTAATTG

ATATTCCAATTCGATTAAATAACTTTACAACCCTATCAGGATCAGACTGAATTAATT GGTTAACAGTCT

TGTGAATAGATAAAAAGAATTTATACTTAGATATATCACGTTTAGTCATCTTTTCTA ATTTTTCAATAG

ATTCTATTCCTGAAATAATATAAATATTATCTAATGATACGTCTGTATATTCACTAA TTCTATCCTTCCA

CTGTTCTAATAATGATTTCATATCAATAAAGATAATTGGTACTGCTTTGATTTTATT AATATAATTAATA

GCACAAAAAGTTTTCCCTTCACCAGTCTTTAACGATAAAAACTTTTGATAATAATTA TTATCATCATTA

AGAAAATTCATTGCATCTTCTTGAATTTTATTTTTAGGTTTATATTTCATTTTAAAA TTATTTTTCCTAAG AATATTTTTATTTCTTTTATCATTAATATGAATATTAACATTTTGTCTTCTTCTTAAGTT ACTAGATAAA

GAATCAATATCAATACCAGAAGGAAATATTGCTTTATCATCATCTATCTTGTATGCT TTAAAATCATAC

TTAAACCATTTAGCATTCCATACAGAAAGACTATTTTCTACAGCACTAGCCATTTTT TCGCTATAGTTA

TTAATAACTATCCTTGTTGGATAAATATCAAGATCCATTCATATATCACACCTTTAT TAGTTTAAAATC

AATAGAATGTATTATATAACTAAATAATACATTCTATTGATATATTTTAATTTAATA TTCTTTAAAGAA

TAAGTGAGGAAAAGATTCAAAGAAATTAATATGGTTAAGTTCTTCAGGACTTTCAGC ATCTGTAGCAT

TAATAATGTAACCAAAAATAGGGACTTTTGAAGTGATATAATATTTACCTTCTTTAA ATGGACCAACTG

TCTTTTGACATTTATCCATTAAATATAATTCACCATCTAACTGGTATCCTACTGAAA GTTTATCACCTAG

TTCATACATTGATAAAAAATCGGTATTATTAATAAATTCTGTAAATTCTTTTGGATT ATTGGTATATCGT

CTGATTCTAAATTTATTTTCATCTGGAATATTATCTAAACTAATAATAAATCTATTT TTTTCTACTTCTTC

GGAATCAATTAAATTATCTTTGTCCATATTCATATATCTATATATCTCCCTTATAAA TAAAATTATCTAA

ATACCCTATCGAATTCAGATTCAACATCTTTACCAAAAAGATCATTATAACTATCTG TCTTAAATTGTT

TTTCAATATTTTGATATAATAGTGACATTGCAGGACTTTTCTTACCGATAAGTATTG CATCACTTACATT

ATATATATTATATTTTGGTAATTCTTCAGCATTAGCAAATTCGGTTCTATCATTATT TTCTAGACTTACC

ATTTCCCTTACAATAGTTTCTACATGTACAGAATCAATCATTGTTCCTGAATCCACT AATAAGTTTACA

ATTTCTTGTACAATGATAGAATAATCATTATTTGATACATTTCTAATAAAATGATTT TTTTCTAAGATAT

CTTTAATCTTTAGAAGTGGGTCTGCAATACCATCATTTTCCACAATAATATTAAACA TATATTCATTAT

CAGGCATATATTTTAATGAGAATACATAATTATTTGTGGAATTATCATAATACTGTT CAATATCATCCG

CAATCTCATTAGGAATAATTAAGCTTAATGGAGTGTCAATTCTAATCTGAGTGTCTT TCCTACCTTTAA

CATAGATTGTTCTTGTTTGATATTTATTCTTTTCAGAGTCTTCATTTTCCATAAGAT CATCTTTATGAAT

ATAGATTGTTTCATTATCAGAAATAGGACTAACCTTATCTTCAAATAATTGAAACTT AGATAAGAAATC

TTTAGACCAGTTAGCATCCTTAATAATAACTTCTAATAAATGCTTTGTTGATAAGAT TTTTTGTGTTAAT

GGATTAGTAAGTTCTAAAGTTGCAGCAGTTCCTACTTTAATGTGTTTATTAATCTTT TCTAATCTTCCAT

AACATCTAGGACATATACCTTTTGAATGTGCGCATGTTATTGGACTAAATATCTTAA TATCTTTACCAA

TAAGATGTGTATCATTCTTAGTTATTACGGTAGTTTTATTAGTATCTTCATCATACA TCCAACGATGATT

ATATAGTGATAACATGTCTTTATCTCTAATATGAATATTAATATAATGAGAAGTGTT ACAACTATCTAC

ATTATTTTCATCTTTGTGAAGTTCTTTATCTTGTGGATCAATATCTAATGTGTATAT TACTGAATCTTCA

GTTAATATAGATATCTTTCGGTTAGTATATCCAGACTGTTTTACTTGATCCTTTGCA GTGATAATTGCTT

TTCTACCACCTACTGCATCAATAAAGAATTCTGTTACATTTTTAATTCCCCTTACAA AAGAACTATTAA

TTGGAGTAGTAATAACTTTACCATATAGATCGGGCTTATAACCAATTAATCCAAAAT TTTGATTAAATT

GTTTTATATTAATTCCTGCACCCGACATGATTAAATCTCTAGTAATATTATCTTTAT CTTCTTTAATAAT

TTGAATCATTTTATCTTTGTTTTCTGCAATTTTTTGATTATTTGTTCCAATATCATC TTTTAATTCTGGAT

CAAGTTCGAATTCTAAAGTTTTCTTAAATTCTTCATTTCTATCCATAATATCGATTA TATCAAATAAACT

ATAAGTCACTCCGCTCTGATATAATACGTTTTGAGTACTAAATATTGATAGTTCATC TACTGACCACGC

AATATCTTTTTTAATCAATTTTATCTTTTCATCACTAATATCATAATTATAAATTTT GTTAATAATCTTAT

CATAAAATACATTATGAAGATTAACATTATAATTACCCTTTTCATTACAATCTTTTA AGATAAATGTAA

ACTCTTCGGTAAATTCTTCTTCCAAACTCTTAAAAGGTTTTGCCAAAATAAACGTTG TTAATAAATTTG ACCTAGATATTTTTGATGTTCCAAATTGTAAAATTTCTCTACGAGAATCCACATCTTCTA CAATTTTCTT

TCCTAATTCATCAATCTTCGAATAATACTTAGTATCATCATGAAGAATTGAATTAAA TAAAGATAGATC

TAATACTGTACTCAATATCCTCCACACAATCCTTTCTGTAATATATTTAACCACAAA TATATAATATAT

AATTGTAAGATAATTTAATAATCACAAACCTATATTATGATTCTAACAGAATATTTC ATTGTTGTAAAT

TAAAATTAACTTTTTATCTTATGAAACTTAATGTGGATCATAGAAAATTTAAACTAT CAATAAAAATAT

ATATTATATATTTGCGAATAAAATCCCCTATCATATAATTATAACACAAATTTATAT GATAGGGGAAAT

AAATTATTTATCTTCGACTTTTTTAGATTCTGATTTAGCTTTACGTTTTTCTCCGAA TTCACGAAGTTTTT

GTTTTCCTTTGCTTGCATACTTAAGTTGAATTGCTCGGCGAGTTTCTCGGCGCAACT TAGAATATTTAAC

GTATTTACGGTAAAGTGGATCATTTGCTTCTTTAGCGGAAATTAATACTGCTTGAGT ATATAAACGTTT

CTTAGCGGTACGTTTATCTAAACGAACAATATTGGCTTCTTCTAGATAGCTTAAAGA TTCTTCCAAAGT

TTGCATTGAACTTTCTTCATTATTATAATTAAAAAATGTATCTTTCATATTGATTAA GCATCCCTTTCTC

TAAATAAAATGGTTTAATAATTATATGTTTATCAATTCAATGCAGAAAAAATAATAA TTTATTTTTATT

CGTTAATAATGTTTTATATTATATAAAATATAGAAAGGAAAGATAATTTATGTATAG TTTTTAGTAGTA

ATATTCTCTTTAATTATATAAAAAATAAAATTGGTGGTGTATTGTTTATATGAAGAT TGAAGAAAAAG

AACGTGAAATGAAACATATTGGTTACATGAAGATATTACTTAATGTTGCTAAAGAAG AATTTCCAGAT

ATGGAAGAAGATGTATTAAAAGAAAAGATTAAAAATATTGTAAAGGATAACATGAAA AATCCAAAAG

CAATGATTGATGATCGTGAAACAACATTATTAGGATTAGACAAATTTATCGTAACTG AGAAACCTATC

ATTACTGGTTTTGGATCAATGTATTTAACTCATGATAAGTTTGATAATCTATTAGCA AAATTGGTTGAA

TATATTATCAAAACTCGTAAAGTTTATAAAAATAAAATGTTCGAACACGTTAATGAT GATGATCAAAC

ACTGAGAAATATGTATGATATGTATCAACGTACCATGAAGATCCTAGCGAACTCATT TTACGGATCAT

TGATCCAAAGTAGCTTTATTTTGTATAATCCGATATCTGGTCCGTCAGTTACTTATT CTGGTGTTGATAT

TATCACTACTGCACTAAATAATTTTGAGAAATTCTTAGCAAATAATATCTATTTTAG AAATGTAGATGA

TATTATTGTATATATGAATAATATTAAATCTGAAAATTATAGTATGGATAAAGTTAA ATTTAAACAATC

CCGTAGTAAAGATCAGATTATTGATTATTTATTTGATAAGACAGATAATTATATGGA TGAAGATAGAA

TATTATTGATGACAATGATGAATAATTATACGGATGAAGATTTACTTAAGCTTTATT ATAAAAATAACT

TCATTGATTTATTAAAAGAATCTGATATTGCAGATAATTATTTTAAAGAAATTCTAA GTTGCTATGAAT

TTACTGATCCAAACGATCCTCCTGCTAAAGTTATCTCCACTAATGAAATTTGTACTA TTAAAGGAAAAG

ATAACGGTAAAATTAAAGTTAAATTATCTAATGGTGAAATTTCTCTAGAAGATCCTA GTAATATTTTAG

ATTATAGGGAAAAATTAGATAATTTATGGAATATTATTAGAAATATTGTATTCTACA ATTATCAAGATT

TCTATCGTATGGAAAATTCTGAAGAAAGATTAAGAAAAACAGTGCTCGTGGTTAATG TATAGCCACAC

TTATATAGTAATATATAGGTTAAAAATTCTATTAATTGCTGGAAAATCCTAAAGCTT ATTTAACTACAA

CGGAATCAGTAATGATAAACGTGAATGTTGTCGAAAGACTGAAAAAATAAATAAGAT TAATACATGG

TGAAATAAAAGTACTATAATATATAGTATCCTAAATATTAATTATAATGGATGATCA GCAGCAGTATT

TCTTTAAGATTATAAATGAAAGAAAAAAGAAATGTTGTTCAACGACTATCAAAAGAT TATTATATAAA

TAATAATTTAGTAGAGTAGAGCCAAGCTTTTGGGTTAGTATTTAAGAGATATTATCT TAATGTAAAACT

ATTAAATCGAAAAATAGAATTATCCTTTAGTAAGGATAAAGATATAGTCTGTTCTTT AAGGAAATCTT

AAAGAAGTTCATAAGAGAACTGCATAAGAATTAGCGCACTTATGTGAACACGAAAGT GATACCGACT CAAACTTCTTGTATCTCAATCACTTTGTCGATTTATTCTCAGAAATTTATCCAGATATTA CGATGAAAG

AAAATGATAAATCTATTGTATCTGCCATTAATACTATTATGTATATTGTTACTGAAT GTATTAATGAAA

CGTATTACAAGTATGGAATGGAACTCGGTATTCCAGAAGATAAACGTGGACTAATTA ATATGAAGAAT

GAATTTCTATATAAACGTTTAATGCTAACAGACGCTCAAAAGAATTATGCTGGCGTA ATTTTAATGCA

AGAAGGAAATATTCTTCAGACTCCTAAGATTGATATTAAAGGATTAGCAATTAAGAA GACAAATACGA

ATAAACATGTACGTGAAGAATTTTCAGGAATTCTTAAAGATGTCATTCTTGAATCAG ATAAGATTGAT

GGTTCTGAATTTATTACTAGATATAAGAATCTAGAAAAAGAAATTCGAAGATCTTTA ATGAATAGTGA

AATCACATTTACTCTCCCTAGAACTGCAAATATTAAAGAAAACTACGTAGCACCATA TACGCAAGCAC

CATACAAAGGTGTATTAGTATGGAACACATTATATCCTGATAAAGAAATTAACTTAC CAAACAAAGTT

AATCTTATCAAGCTAAATATTGAAACTTTTGATGATATTGAAAGTAAAACTAATGAT CAAGATCTAATT

GAACGATTTAAGAAAGTTTATGAAGATGAGGAATTGACAAAAAAAGGAATTACTTAT ATTGCTATTGA

AGCAGAACAAAAACATATTCCTGAAGAAATCATTCCATTTATTGACATACCTGAAAT GGTTAAGACTC

ATGTATCATCAGGATCCAAACTAATGACGTCATTAGGATTCAATCCATTAGTAATTA ATGGATCATTAT

TCCCAACAAATATTATTAACTTTTAATGAAAGTAGGAAATCTATTGGAAAATTTAAA TATTGATATGA

ATGATCCAACCAAGAAAAAACATATTGTGGTAGATTGTGATGAAGTATTATGCAATA TTTCACCAAAA

TGGACATACTTAATACATCAAGAAAAAGACTATTTTGGTAAATATATGAATCTTATT GATAATTTTGAT

ATTGATCTGCATTATAATATGGTTTTATCTAGAAATAAGTTTTATCTAAATCAGTGG TTAATTAAAGAT

GAATCATATACGAATTATAGTGAAGACGAAATGGATGAAGTATTAAGACGTATGATG ATGCTTTATGA

AACTGAAGATTACTATGATAACTTAAAACCAAATCCTATTGTAGAGTCATTAGCATT ATCGATTCGTCA

ACCTATTTTAGATAGAATATCTATTGTAACAAGAACAAACGCTAAAAATCTTAAGTC TAAAGAAAGAT

TTCTTAAGAATTGTTTTCAAGGTGTTATGAATAAAGTTGATATATACTTTGTAGAAA ATGATGAAAATA

AGTCTGATATTATTAAAGACTTAGGTGACGGTATTGCAGCTATATATGAAGATGAAG TTAAAAATATT

GTAGACATTTTAGATAACTGTAATAATCTTGATAAAAGCTTAATATATGTACCTAGT TATGGATATAAT

AACGCTAACCTTGATTTATATACTAAAGCAGAAGAAAAAGGAACTCAATTAAGATAT TATTCATATTA

AAGGATGTGGACTTATTATGTATAATGGTAATTATGATATAAGTCTATATGAATATT TAAAAAGTAAA

CTTAAAGTATGCTATATCACAAGCAAAAAGGATGAAACTGTTATACGTTGTCCTTTT TGCGGTGATTCT

GCAAAAAATCAGTATTCTGCACACTTATATATAAATAATAAACCACCTTATAAATAT TATTGTCAAAA

ATGTAATTCAAATGGAATATTTAATGATAAGATACTTAATAATCTAAATATTTTTGA TGCAAAACTAAA

TCAACAACTTAAAGTATCATACGAAAAATTCATTAAAGATGCAGGAATAAAATATGG AAAATCATTTT

CATCACTATTTAATATGGATGAAACGGACATTCTTCCAAATAACTTTGGAATGTTAG AATTAAGAAAA

ATAAAATACTATGAAGATAGATTGGGAATAAAACTCAATGATGAATTATTAATTAAG TATAGAATTAT

TCTTAATCTTAGTGATTATATGGAAAATAATAAAATTCCAATAAAACAAGACAAATG GTATATTGAAA

AATTAAAAATGATTAATGATAATTACATTATATTCTTATCTAATGACAAGAATGTTA TTAACTGCAGAA

ATATAACAAATGTTACTGAAAAAAAGAAACGTCATATTAAAATGAGACTATTTGAAG ATTTTACTGAT

GAAAGTAGAAGTTTTTACTCAATAAAGAATAATATATCTCTTGATAAATCTTTATAC AATATTCATTTA

ACAGAGGGTATATCTGATATTATATCCGTGCATCATAATATATTTAAAGATCAGGAA AATAATAATGA

TATTTTTATATCTAGTAATGGTAAGGGTTATAATTCGGTATTACAATATTTATTATC AATTGGGATTAC AAACGCAAATATTAATATATATGGTGATTCAGATGTTAATCGTAATTATTATAATAGATT AAAGTATA

ATTTACTAGCTAAATATAATGGGGTTAATCTCTATTTTAATATTGCTAAGGATCCTT ATGGTAATGGAT

TTAAAGACTTTGGCGTAAGATCTGAAAATGTAGAATTAAGTAAAAGCATTAAGATTT CTTTCTAACTTA

ATGGATCATAGAAATTTTCTAAAAAAAAAAAAGACCCTAATAGATATTATATCTATT AGGGTTATATT

TATTTAATTATTCTTTTTTTAATTGATAAGGATACACATTAATATATTTACTATCTA ATAAATCATACAC

ATTAATTAACCGACCATACATATTAATCTTTGAAATTACCACATCGTGAATTTTTCC TAAAGAATCAAT

AATATAAAAATCTTTTCCTACAATAATATTTCTATTATAAATTTCTTTCATGAATTC ATCTAATGAATTT

TGGTCTAATTCAGTATTATACATATTAATCATTTATATTTCCTTCTTTCTTTTTTTT TTTAATATATTTTCC

ATTTCATGATAAGGTATATTCATTATAATTGATACATCATTAGTACTATAATTATCA TCTAGATATTTAT

CTATTAATCTTTTTCTTTCAGAGATGCATTTATTTTTAGCAGTATAATGATCATACT GTCGGTTAGCACT

TTTAAGTTCTTTAAAGAATAAACTATTATTGTTAATATATTTTTTAATATTAGATTT ATCTACTGATAAT

TCATTAGCTAATGAATAAACACTGCTGATATTCTTCTTATTGATAATATCAAGAATA TATGATAAACGA

GAAATTCTTTTAACTATCAAATTGCAATCTTTAACTTCCATATTAAAAATAATATCT ACATATTTTTTCC

ATGATGGAGGATTATCGATAGATGTAGTTTTATTATTTAATAGTGAATTAAGATATA TGACAATATCTT

TATTTAATTTGGTATTATTTATGATATCATCATATTTTCCTTCATCATAATTACGTT CTATATATTTTGTA

AGGTATTTTATTTTTTCATCATCAAGACTAAAATATGTCATATATTTCTTAAAGAAA GTATTTAACTTTA

ATTTAGTATATCTTCTTCGAATATTAAAACCATAAACAAACACATTAGTTACTGTGG TATCTATATCTT

CCATAACAGTATTAACTTTAATATTATTATTAACAGTATTAACTTTAATATTATTAT TCTTAATAAAATT

ATTCATGTTCTTTATTTCATCGATAGTATTAATGATAATATTTCTAGACAATAATTC TTCTTTTTTAAAA

TTATTAATAACTTCTGTATTATTTAAAGATAAAATGAAGGCATTTTTCATCTTTTTA ATATTATTTCTAA

TAACTTTATTAATTATATTTATATCAACACTATAAGTTTTTGATTTTATGTTATTAA ATATATCTAGGTT

AGTAATAATATCTTTTTTAGTAGATAATTTTAGATAAGTGTTGATTATAAATTCATC TATATCTTTAGGA

TATATAATATACAATGCATCAACCATAACCTTATTATCATAGATAAGTTTAATTTTA ATTGATAATTCT

TTTTCTAGAATATTAATACAATTTTCACTAATTGATGTCTTAGTATTAATTTTTTTA CCATAATGGTAGT

CATTTCGTATATCACATATTATTGAATGTTCTAGATTAGTAATTATATAAATTTTAT TATATAATTCTTT

ATTATTCTTTATAATATTATTAACACTATAAATATAACCAACGCCAATATCATAAAA TATATCCATATT

TGTAACAAAAGAAAATTTCTTTTTTAACTGATTATATGACTTGATAATATTCTTTTC AATACTATCAGTA

CTTCCATCATTAAATATCAATTTATTATCCTTTAGATATTCTTTAAATGAATCTAAT ATAGTATTATAGT

TATCTAGATTCTTATTGAGTACTAAAGATATAATATCAATGTCATTCATTTTTCGAT AGTTCTTAATACT

TTTGACAATACTTTTCTTTGTTGGAATTTTTATATTGTTCTTTATATTTAATTCATT TATTGTATTAAATG

GTATATTACAGTATAATAATATATCATCTAAACTTAAATTTTCAATAAAAATTAATT GAATAAATTCAT

TATAGTTGATGTAATTATTTTTAACTTTATTTTCTTCAGTAATTCGTATTCCTTTTA ACATGGAATAAAG

CTTTGACTGATCATAACTAAATCCTGATAGTTCAGAGATTTCTTCTAAGGTTACTTT ATTAGGATTAAG

TTTATTAATATTATTTAGGATAATATTATCAACAATCTTAGCTTCTGAGATATTTTT GTTCTTCTTATTAT

TTTTAGTTTTATTATCATAACTAATTTTCATTTTTTTATCAAATAGACCGGATTCAT CAATATATAGATT

TACTACACCTACTGGAACTTTATATTTCATACATATTGACTTTAAATCAAAATTATC ATTAAGATATGT

ACTATCTATTTCATGTTTTAATTCCTCGCTAATTCTTAACATCTAGTTATTCCACCT TTTAAATATTATTA AAGAAAAGGATAATGAAAATAAATTTCATTATCCATATAATTACAATGCAATAATCAAGT TTGTTTTA

GCTCTAGTAATTCCAGTGTATAATTGTTGATGATATATGCTCTTATTATATATTTCA TCAAACAGTAAT

ACATTATCATATTCCGATCCCTGTGATTTATATACGGTTGTTGCATAACCAAACTTA AACTTATTAATG

ATAACATGTGATTCTTCAAAAATATTTCTTCGAAGAATTAATGACTTATACATTTCA TTTTCATAAATTT

GATCATCATTAGTTATTCCATCCGTAAAATATAATGCATCTACATGCAATCTATTAT AGATTCCAGTAT

CTGATGAAAATGTAGGTTTAAAGTCTAATTCAAAAGTATCCAACCTTTTCTTATATT CATAGATATTTT

CCACATAACCGATAATACCATTTGTTAAATACTGTTGTGATCCATTATCTTCATACA TTTCTAACCAGTT

ATTCTTAAGACATATTAATTTTTCACCAACATATGGAAATGGTGAATTCAAATTAAG TATATTTTTTCT

AATAAGAGAGTTTATCCTATCAACAGTTATATTTTTTGAAGCTAGAATTTGATCTGC GCCAGTATACAT

ATCATAGTCTACATCTTTTTTATTAATAATCATTACATTTTCATCGATAGGACCAAT TCTTAATCTATTT

TTCTTACGAACTTCATTAGCTAACCATATAATTGGATTATCCAGTGCTTGCCTTAAT GGTTCATCTAGG

AAGATATCTGGTCTTTTCATATATTTATTAATTCCACCTTTAACTGGTGGAAGCTGC ATCGGGTCTCCA

ATCATAATGATTGGGACGTTAAATGTAATTAGTTCTTCAATCATTGAATCTGTAACC ATACTACCTTCG

TCTACAATAATTAATTTAATATTTTTTGAAATACTTTCTTTTTTAATAAAGTTAAAC TTATTCTTTTTTTC

ATCATAAACTACATTATACATTAACCTATGAATTGTTGAAGTGTTATTATTCCCTTT CCTATTAAGAAC

ATTAGTAGCGGTTCCAGTATATGCAGAATATACTACCTGTTCATCGTTTAAATTGAT TGCCGAAGTTAT

AAATTTTATAATTGTACTTTTACCTGTTCCGGCTAATCCTGCTATTGTAAAAACTTT TTTAATATCTTTA

TTCCACCATTCAACTGCTCGCATAACAACCTCTTCTTGTTTGTTTGTTAGCGTAATA ATACTCATTATAT

ACACCGCTTTCTATCCATTTTATTTACTATAATTTTTTATTAACATTATAAATTACT TTTTCATTAATATA

ATATATAATTAAAAATTTATACAACTTTCTAACATAACATTATAATAGTAAATAATG GCGGTGATAAA

ATGTCAATGAGAGATATGAATGGAAATCGTATTATGGACTCATTTAGCTTCGATAAA GAGTATGAAGG

AATAGTATTAGATAATAACGATTTTGACGATAAACTATTTATTAAAGTATATATCTC TGAATTGTTTAT

TAATGATATTCCTGAGAAGGTTATCGATATTAATGAAAATATTGATCATACTAAAAT AATTAATAATA

ATAAAATAAATTTTAAAAAATCTGTAGTACATAATAATTATTTGAAGTGCTATCCAA TCATATATAATA

ATATGAATCTTGATATAATGAAACCAAAAATAGGTTCAAAAGTTATTGTCAAATTTA TTAATGGTAAT

CCAAAATTGCCATATTATGAGAATAAAGGATATTATACAGATATTATTATACCAATT CCTCCCGAAATT

ATAGATCCTCCTACTGATCCATCCACTAGTGATGATTATACTTCTTTTGGATACTAT AGAATGATTAAA

CTTACTAATCCGGCTATGATTGGTCGAGATATACTAAAAATCCAAAAGAAATTAAAG ACTCTTGGGTA

TACATTCACTATTGATACACTAGACGGTATATATGATTTAAGAATGTTGAATTATAT AAAAGATTTTCA

ATCTAAAAATAAACTAAGTGTAGATGGACAGATTGGTCCAATTACGTTTAGAACAAT TATGCGTAAAA

ATATATAATTTTTAAATTCGAACATATATTTATAGTAAGATAGTTTACTATAAATAT ATTTAATTGGGG

TGGAAATTTTTATGGAACAAGTAACTTCTGGACTATTAATTTTGACAGTATTATCCG TAGTAATTCAGT

ATTTAGTTGAAAGAATTAAAGATATTTTTCCAACAAAAGTTATGGATAAACTAGCAA ACTATGTTAAT

CCTGCTTTCTGGTCTTTAATTGTATCTCTTCCTATTGCTTTTGGTATAAATATTGAT TTATTTGCAATTAT

CGGTTATAATATGCATCCAACATGGCTTGCAACATTATTTACTGGTTTTGCATTGAG TGGTAGAGCAAC

TGGTATTAATGAACTTATTAAATCATTAAGTGCTGTTAAAACTAATAATTTTACTCA AGCAGATTCGGT

AAAAAATACTGATGAAGAAGAAATTAAAGTTGTCGCTAAATCTAAAAAATAATATAT ATCCCTATAGT GTATAATTGCACTATAGGGAATTTTATTTACTAAAATTATAAAATACATAATAAAATAAC ATTAAAAT

ATATTTACATTAATATACAGAAATGGATGATTAAATATGAAATATCCGATACGTGAG GATCATAGAAA

AAGAGTCAAGACAAATTACATTATTATTACTCATGCTAATAATCTTATAAAAAGGGG AACACATATAA

ATAATGCATTGAGGCAGAGAACTTTTAAATACACTTGGGGAATATGGCAAGAATATT TAATGACTCAC

GTTAATAAAAGATATTTACCAATGCATTATTTTATTGAATTAATTGATAAAGATTAT GCAGTATTGAAG

GGTCTTTCTGACCATAAACCTTCTTACTTTATTAATGATTTAGTAGACGAAGGTGTA ATAAAATATGTT

TACCGAGATTCGATATTAATAGTCATTGGAGATAATTTTAGTATAAATAATCCTGAT ACTAGAATGATT

GATCATTTAGCAACTAAAGTTATTCTTCCATTAATGAAAACGTATAATTTAAGTTGG AATAAAATACA

_{ATTTTTTGATGAGTGTTTAACTGACTCATTTATTAATAATATTGATAATGATGAA ATAAAATATAATTA}

CGAATATGAACCAATGTCTATGTTTGATATGAGTATTCTAAGAAATGCAGTACTTAG ATATAAATCAT

AAATATAAAATAATAATTATAAGTATTGTGTGGTGATAATTGGAAATGGATAATAAT CAAAGACATAA

GAATAGAAATTTTTTTAATATAATGATAATTATAAATATTGTAATTATTGTTATAAT AATTGTATCTTCA

GTATATCTATATATACATATAAATTCAGGAAACAGTTATTCAAAAGAAACATATGCT AAAGTGAATAA

TGTGTATATGACATATGATAATGAAGATAAGGATATACAAGTAAGAATTGGTAAAAA GAAACTAATA

ATATTTAATAATGGTAAAATTAAAGAGATTATATTTAATAATTTTGAAGTATCAGTA TATGATGAATAT

ACTTTAATATACATTTCTGGAGATAATGATGAAGTTAGTATTTCTGTAGACAATGAT AAAGATTCCATT

TCTGATATAGTCATAAATAATCAAAGTTTAATAGAATAATTATATAGATATATAGAA GTGTGGAAAGA

AGGTTACAATATATGCTCATATTAAAAATGAGAACTGACAAAAAAGTAGACTATAAA AAATTATGGTT

TATAAAACTTCATAGAAAATTAAATATTGAAATTCATTATAATATAGAGGAAAATGG ATTCTACTATA

TTGATAATAATAAAACATTAAAACTTAAAAAAGATTTTTCAAGAACAATTAGTATGA TTCTTGATATTA

AGAAAAGATTCAATTCGTTTAATACTGAAATGGATATAATTGATAATAATATTAATA TGTATCTTAATG

ACGTTATAAATAACTTTGAAAAAGAAGAAATGCTAAGAATTATACTAGGAACTTCGG AATATAATGTG

AAGAATCTATATAATGATCTTACTGAATTAGGAATTAATATTGATCCAGACTTATTA TATGTAAATTTA

TATAAAAATACAAAACATTCCGAATATAATGATGAAATAAAGAATACATTTAAAAGA ATTTGATAACC

TGAATACTAATAATTAAAATAGTATTCAGGTTATCAATTTTTATCGAGCAAAAAATA TTTTTTTCCTTCT

TGAATGTTTTAAGGCACCAATGCGCATTTTTTCAACTAGTTCTTCTTTCTTATTTTT TCCATCAGCTAGA

TCTTCAATAAATAATTCTATACTGCCATACGTTGTTTGAATATTTTGAAAGCGATGT CTAATTTGATAT

AATGATTCTTGAGTATCATATAGACATAATTGCATAAAATGTTCTTGAAGATTTACT GGTATGCTGTCA

AAATGTTCACTATGAACTGCGTTTGCATATACTAGAATTCCGTTTAATGTATATTGG GGAGCAATTTCA

ATTTGGTTTGGATGAATAAACCGGAATGTTGAAGGATTTATTTGACCTTGAATGTTA CTCATCATCTGA

TTTTCAAATAAACTTCCAGAACCAGAACCAGCTCTAGGAGTTCCTCCGATAATTGCA CTATTACTACTA

TACATATCTAATCCAATTACACGATTAATATTTAATACGGAAGTCTCTGTATCTAAA TAATAACGATTC

TCATATCCCGGAACAAGATCTTTATTAAATACTCGGATTTCTTCAATTCTTGGGAAA TACTTACTAAAC

GTAATCAAACTTTCTGATCTTATTCCACTAAGAATTTCTTCATGAGAAAGTTCTAAT TGTGTAAATTTAT

ATCCTAATTTTCGTTCTAAGAATCGAATAACCTCTGTAGGATTAATCATTTAGTTAT CACTATCCTTCCA

ATAATAAAAATACAATACCACTTCCTAAATTTAATTAAGAAGTGGTATATTTTAAAA CATATCTTGTAT

ATATTTGCTTAAATCACGTTTAATTTCTTCTTCGAGATAAATCCGGATAGTTTCGTT TGATTGTTTAATA CTTAATGTTTGATCTTCAGTAAGAGTTACTGAACCATTCTCTAGATTCATAGATATACCT AATGATTCT

GCTAATGAATATACATTTTCAGATTTTTTAGTAACAAACTCTAATAATTCAGAAACT TGATAAGGAACT

ACTTTACCTGAAAGATTATATGAGTTTGAGCTTGCTGCTTCTAACAATCCTTGATAA TCTTCTGAGAAG

TCTTCATTAATCCGGTGAGTCATATATGAGTTTGGATGGGATGGAATAACAACCCAA TCATAGCAGCA

AATCATTAAAGGTGAATGAACTCGTTGATACTTCCCATCAGGCTTAATAATATTACC AATACCACGCAT

GGAGAATGCTGCCTTTGATCCTTGATTAATCAAACCTTTCATGTCTCTACCTACAGA TGTATCTGCAGT

TTCAACTCGTCCAATTAATCGATTCCCATCAAACTTAGCTTCAGTTACAATATGCGA AATATTGCGTTG

ATCAATATATAATTGTCTACGATTATCAGTATTTAATGGATGACCTGCTTCTCCAAA GAATGTTCTATT

TTTAATTTTTTCCTGAACAATTGGGTTTTGTATTGCTTCATCAATTGCACGTCTATC ATAAATACGGTTT

TTTTGTTCTGGTGCATCAGCTTCTTGCAACTCAGTCTCGAATAATACATTATTAAGT GTTTTATCTATAA

TTTTCGGTTTAGATTCAGTGACCGATTCCATTATAATATAACCTTTTTCTTCAGTCA TAATAGTAATACA

CGTCCTTTCTTAGTATATAAATAAAATTTATAATAAAATGTTTGATTAGATAATTAT TTTTTTAAACAAC

TTATTATAAAATATTCTTTTTATCATTTTTGATAAAATATGTTTTAAATTTAAAGAA TATTAAATTATAA

AATAAAATGATAAGGTGGGAAATATAAAATGCCAAAAACTTTTTTAGATGTAATCCT TGAAGATGCAG

ACGCATTTGAAGCTAGTAAATCTGTTGAAGTGGTTGATAAAAATACTACTGAACCTG AAGTAGTCGCT

AAAGATGAAAAAGCTGATGTAGAAGAACAAAAAGAAGTATGTGACGAAAAAGAAAAA GCTATTGAA

AAAGAAAAAGAAGAATATACTAATGATGCAGAAGTTGAAATTACTAGTGACGTTTCA TTAATGAATA

ATGTTGCTGATAAATTAGATAGTGGTATGTCTATTGAAGAATCATTCAATTCTCTAA TCGAGGTTAATC

TAGTTAAGAATGAATTTAAAAACATGGGCTTGACTTCTGAAGAAATTAATCTTCTTG CTGAAGATGCTT

CTAAAGAAAGAAAAGGAATTATACGTGGATTGGCTAAAAAAATCGGTATCGATGATA GCGGTAATGT

TGATGCTCGTAAATATGTTAATGCTCGTAAAAAATTAGGCGTAAAACAAATTACTGC CGCAGTAACTT

CTACGGTTGCTGCAAGTGCTGCTGCTGGAGCTAGTAGCTATTATATTGAAACATCAA AAAGTAAAAGC

GAAACTGTTAAAGGTGGAATCTTTTCAGGTTTAACTGTAGGATTGGTCGTAGGTTAT TGGGTTTCCCTT

TTCTCATTTGTAGTTACTATTTTGCAAAGTGCTAAAGTTAAAGGTCAAATGAAAAGT GATCCATCTATC

TTAAGAAATGCTCTTGCTGAAAATAAAAAAGATTTAGCTGAAGTTGTATCTTCTATG TCTAAAGTTAAA

GAAGATGCTAAAGCAACCAAGCAATTAGAACGTATTCAAAAAGCTTTACTTCGTGAA AAATCCAAATT

ATTGAAATTGCAAGAAAAATTAAATACAAAATAAGTTATATATGATCTCAATTCTGA TTAATTTCAGA

ATTGAGATTTATTTAAACATTATTATATAAGAAAATATATATTGGTGGTGATTTCAA TTGCATCTAGAT

GAGGAAAGTATTAGATACGCTATAAAATTTACAGAATCTTTAGAAAAAAATGATTTT GAATATGGTCA

AACAATTCGTGAAGAAATTCAAAATGAAAATAATTCATCTCAAATAAAAAATATTAT GAATATGCTCA

ATATTAAAAATCCAAATACTATTACTGTTGAAGAATATTTAAAGATACGTAGAAAAA TTAAATTTTCG

GGTCTTATTGGATTCTTAGCAGGTCTCGGAGGAAGCGTAATGTTTACTTCAGATATT ATTATAAATAAT

GATCGGCTTAGAGACGATCCTCAAAATAGAGGAGTCGCTAATAGAAATAATCGTAGT AAGCTAAGTAT

GCTTAAGTCAACCTTATTTGCTTTAGTTTCGGCTTTTGGTTCATTTGCTTTATCAGT ATTATATAGTAAG

AGCGTTAAGAAAACTTCAGTAGCTAATCCATCAATAGTTAGAAGTTTATTAGCTATT AATGCAAATGA

CTTAAGAATGGTAGAAAAAGCAAATAATAGTGTAGTTACTAAGTCTGACTTAAAATA TATACGTAGAA

TAGAACGAATATTAATTAGGGAAAAAAGGGATCTATTAAAATTGCAAGCATACGTTA TAAAGAAAAA TAAATGAAAGAAGTGAAAATTTTTATGGAATATAATGATGTATTTTTAGAATATTTAAAT TCTGAAGA

AGATAATATTGAAAATATGGAAGAATTCCTATCAAGCTACATTGGAATTAAACCAAG ATATCTTGAAA

TTAGACCTACTGTATTTAGTGAAACAAGAATTACTAATGATGGTATTAGTGATGAAG AAGATAATAGC

GAAGAATCTGATCGTAAAAGATCTACTGATGAAGTAAAAAAGATTAGTAGAGAAGTA ATGGAAAAAG

ATAAGAAAAAGAATCTTAATCCACAAAATAAAGCAAAAATTGCAACTATTAAACGTG AAATGGAAAA

ATCGATTAAAATGGATCCAAATAGTCTTGGTAATGATACTAAACTTAAAAGACTTAT GCGTGTAGGAA

TTACAATGTTAGTTTCTTTCGGGATTATTTTTGCTCCTGCAGTTGGTGTCTTAATAA AGATTATTGCTCT

TATCGGAGTAGCTGCTACTGCAAAACACGTTAATCGTAAAAAATTGGAAAATACTAT TATATTACTAA

TGGATAAAATTAAATATATTGAAGATGAAATGGAAAAAGCATCAGACAATCCTAAAA AGAAATATGA

ATTAACAAGAGTAAAACGAGAACTCCAAAGAACACTTATGAAGTATCAGTCTAGACT TCGGAATTTCC

ATTAATATATGATTTGTATAAGCGATGTTGCAAAGGAGGTACTATTATATTGAAAGA TGATTTCTTTAA

TTATTTATTTGAAGCAGATGATCCAGAAGAAATAAGTAATATTGATCCTAATGAAGA TAATACTGAAA

ATAATAACGAGGATACTCCTTCTAATGAAGAAAGTTTACCAAACGAAAATAGTGATG AAAATGATTTA

GAAAAGGATCCAGAAATAGAAGAACCTGATAATGAAGAAGAAATAGAACCTAATGAA AATGAAGAC

CCGAATAATAATTTACGTATAAAGGAAATATTATTTGAGAATTTCTCTGGACTTAAA AATGCAATTAA

ACGATTATTTACTGACATTGAATCGGTAATACATATCGTAAAATCATATGATTCTAA TAATGATAATCA

TAATTTAGAAAATACTGTGGATGGAATATCTGAAAAAGGATATGACATTTTAAATAA AATTCAAACAT

TACAAAATGGTGTAATTCTTAATATATCAAACGATAAATTAAAAATCATATATAATG AATTAGAAAAT

CAAGTAAGTGATATTATTAAGGAATATTCAAATAAAGTTGATGTAAAGTTGAAAAAC AAGTATTAATA

ATATAAACAATTTAATATAAAAATTTTAATTTATTTCTATGTAAGTTTCGTTTATTA CTTTTTTAAAGTA

AGAATGATGAACAATTATATATAAATAATTTATAATATTATTTTTATAATCTATAAT TTTATATAAGAA

AAGGAGAGAAATTAAATTATGCGTAATTTTAAACGTATTACAAAGACTAATACAGAT TCTTTTAGTAC

TCATCTAAGCGAAACTCAAGACTATTTCGCTAATACTAAAGGAACAAATATTACTGG ACAAGATATCG

CTGCAATTATAGTGAATGAACAATATTTTGATGAGTATGCAACTCGTCTATTAGAAG GTTTCGATGCTG

ACCTTAGTGAAGAACTAGGTGTTCTTTTAGAAAACACTCGTAGCAACATTATGGAAT CCTTGGGTGGA

ATTACTCCATTTGCTTCACTTTCAATGCCTGTTTTGGTTAAACTTTGGGCTCGTTTG TCTATGGTAAATG

CTATTCCTACTACTCCTGTTACTACTCCTGCATTTGTAGTACCAACTATCAAACCAT ATACTATTGGTCC

AGATGGTGAAAAATACTACCTACCAGAAGCTATTAATACTATTCCTGAACACTTTGT AAGTCTTCGTCA

ACTTAAAGAAGATATCACTATTACTGGTGGTCGTCTTTCTGACTATGATCTATTTAC AGGTGTATCAAC

TGCTGACCGTGCTAAAGGTGATCAAGTAGACCGTAAATTCCAAATTGTTGCAGGAAC ATGGTCTGATT

CTTATAATGTCGCTGATGCTGCTCTTGGCGAATATGAACTTAAAGGTCAAGCTCTTA AAATGGATATTC

ATGGTAATATCTTTGGTAAAGTAACATATACTACTGATGGTAATGGTGCTACTAATG AAGATACTATTA

TGGGACATGTTGATGTTGAAAAAGGTCGTTTAGATTTAACTTCTCTTTCTGGTAAAT TGACTGAGTTCA

AAATTCAAGGTTTCGTTTCTTCTGAAATGCATACTGGTACAACTCAAGTTGGTTTTG ATGTTGATGATC

GTACAATCAACATTGGTACTGCTCCACATATCGAAGGTATCCTACCTATCGAATCCG TACAAGATAGT

AAAGCTATGTATGATATTGATGCAGCAGCTGTTATTGTTGATACAATGTCTGCTACT TCTGCACAAAAA

GTTGATACTGACTTGATTGAATTCTTGTTACGTTCTTATGAAGGTACTAATGCTGCT TATCATAAAACTT TCGATGTACATCCAAATGGTGGATACAACATGCATCCGCATGAATGGCGCCGTGGTATTC GTGACGTT

ATTGACTGGATGTCTCAAGCAATGAAAAATGATTACAAAACTTATGATGCTTACTTT GTAATTGTTGGT

AATCCAATTGACACTCAATTGATTCCTGACATTGAATGGGAATTCCAAGGAGCTACT GATGAAGTTGC

GGGAATTAACGTTTCTTATAGCGTTGGTGCTTCTTCTACAGTTAACCGTTATAAAGT TGTTTCTTCTGAC

TTAGTACCTGCTGGAGATCTATTAATCTTTGCAGTTCCTACTCGTGAAGACTTCAAA ACTTACGAATAC

TACCCATACACTTTCAATATCGTTAATAATTACAACAATGCTGTTAACCAAAGCGTT CCTAACATTATG

CTTTCTCGCCGTTATACAGTTGAAGAATTTGTTCCAATTATCGGTAAAGTTACAATT AAAAACAACGAT

GCAACTCAATACGCTCGTTAATAAATATTATGAACCTTTCAGAGACCTTTTGGTTTC TGAAAGGTTATT

ATTTATAAAAATTTAAATTGGCGGTGCAACCATGCATATTGATTATGGTATTGAAAA GAATATATCAA

AGTACTTACATGAAGAATTACTAACTGAAGATATCTATAATCATCCTTTATTAAAAA AGATTGATGAT

GAATTTCAGAAAATATTAGATGAAGATAATATTAATGATACTAAACTACCAGTAACA TCATATAAAAA

AATTCAAAATATAATTAAATATGTCTCAACTATATTTAATATAAATTTAATTATAAC GATTGATAACGA

TAATATCCTTACTTATGGAATGATGACATTTATTCCGGTTAAAAATCTAACAAAGAT ATCTAATAATAT

AAAGAAGATTGTACTTCAACCAAAAACTGGTTTTGAATATATTAAAACTGAAGTTAT TGAAATTAAAA

TACAGAAAAAATTAATATCTTTCATTAAGGATCCAAACTTACTTATAAGAAATAATA AAGTTCCAAAA

AATTATACTCCTAGTGGAAGAATATTGACCAGTATACTTCTTCATGAAGTAGGTCAT CATATATTCATT

GGATTTGAAATTAAGAAATCTATTAAAAATGATAAACTTTTTTCAATTAACGGTGGT AATGGTAAAGA

AATAACTATACCTAGTAATGTTAATAATAATAAATATGTATTAACAAGCACTATATT ATCTATATTAAC

GTTAAGTATTTCTATGCATAGTTATATGAGAAGTGAATACAATGCGGATAACCTACC AATACAATATG

GTTATGGTAAAGAAGTATTTTATTTTTCAGAATTAATGGAAATATTAGAAAAACAAA AAAGAAATTCA

ATTCTATTAAAGATTAAAGGATTTCTAATGTTTGGTAAAGATAATTATTATAATCGT AAAATAAAGAAT

CAAGTAATTATTATGATGAAAAAAGAATTAAATAATGATAATAATAGTCCTAAAGAT AAGGAAATTAT

TATAGATAATTTAAAAACTATAGAAAATCTTGAATAGATAATGTGGTATAACTTATT AATTAATAAGTT

ATACCATTAATACGCAAGTAACTATTAATTATAATAAAATAAAGAAATTGTGGTGAT AAAAGTATGCT

TAAGATTAATATTAAAGATAATCCTGAACTTAAAAAGAATATTACTTCAAAAAATAA AAAACTCTTTT

ATGATTTCAATACAAATAATCAATCTTTCCTAGAATTAGCTATTGAATTAAAAAGAT TGGGAATCAGA

AATAATAAGTTACATTTAGTTTTATATGATAAGAGTCTTTCCGGAGTAGATCCGTAT GACCCGAACTTA

ACTGATAACGTAAAGGCAAGAATTGTTAAAGAGAGCATTATTAATTTTTGGTACTTT ATTAGGGAAGT

AGTTCGTATTCCAGTTCCAGGATCTTCAGTCCATTTTGCTATTCATAGAGGGAACCT TGCAATGTGTTT

CTGTTTATTAAATAATTTAAATACCGTATTAATGTTACCTCGACAACATTATAAGAC ATATAGTGCTGT

AGGTTTTTATTTATGGATTGAATTATTAGTAGGTAGAAACTATCAAATGATCTTTTC ACATAAATCATT

AACGGATAGTATTGCCAATCTAAAAAGATTGACGGCTCTATTTGAACTATTACCGAC ATATATGACTG

AACCTATCTTAAATAGTAAGAATGATAAGAATGCTGAAACTATTTTAACAATTGACT CAATAAATAAT

ACCATTAGGACAATTGGTCCAAGCACAGATATTGCTTCAGCAGATAAGTCAGGTTAA CTTAATTTTTCG

GCTTGACTATAAAACTTTTTTAATTGCTGGAACATCCTTAAGTCTATTAAACTACAA CGTAACTGGTAA

CGGTAAGCGTGAATGTTTGAAAATTAATAGAATTGGACAATCAGCAGCCAAGCTTCC AATGATTATTG

GATGAAGGTTCAACGACTATCGAAAGGGTAAATTTATATTTTAAATTTAGAACTGAG TAGAGTAGAGC CAAGACAAAAATTTGCAAGTTTACTTGGTTAGTAATTAAGTGACATTAACTTAATGTAAT TCTATTAAA

TCGAAACGGAAAGTATAGAATAAAAATAAATATATATTATAATAATGATGAGATAAT TTATATCTTCT

TTAATTAAGATTATTAAAGAGGTGATTATTATGGTAAGAAAAAACACAGAATTTGAT CTAGTTAATAG

AATATCACAAAAATTCAGTAATAATGAATTTACCTATATTGAAGGGTTTAATAGAAT GATAGATAAAT

GTAGATTTAAATGTAATAATTGTGGAAATGATAATTATTATACTTCGCCATCCATAT TATTGGATAAAA

ATAAATCTATATACTGTAATCTATGTAATCCTGCAACTTTACGAAAAAATTCATTTA TGGATAATGTTA

ATAAAAATTACACTGTTTTAGAAAAACCTAAAAATAATAAACAAAATATATCTGTAA AGTGTAATTTA

TGTGATTTCATATTTAAAACAAGGTCACAATATTTAACAGCTATGGACAAACCTAGT AAAACTCGAAA

TTTGTGTCCTAAATGTAATGCATCAAATTCTGAAAAAATATTTGCAAAATTTCTTGA TTCTCAAAATAT

TAATTATGAAATGCAGAAAAAGTTTAAAGAATGTATCGGTATTAATAATAGAGTCAC TCCATTTGATT

TTTATATAGATTCAATGAATCTAATTGTTGAAATTGATGGAAAACAACACGATTCAT TAAAATATGCAT

TCCATAGAGATATTAAAGAATATGAAAGAACTGTTGCTAATGACAATATTAAAAATA ATTTTTGTAGT

GAAAATAATATTGGATTAATACGTTTAAGATATAATTGCAAAAGTAAAGAAATTGAA TTCATGGAATC

AATTATTGATGCAAAATATATTCCAAACGTAAAATTATCCATAAATGCAAATCTTAT TAAATATTAGAT

ATAAATCTCATCAATTTATAATTCTGACTCTTCAAATAAAATTTGGAGAGTTTATTA TTTTTAGGTTTTT

CTATAAAGATATAGTCTATGGGGAGAGAAATCTCTTAAACTTGTTATATTCTAAGCG AGGAATGACCG

TTGTATGCGCCGTAATGAGTTTATAAAAACTCTAATCAATTTTGAGAATAACGGAAT GATAGATAGCA

AATAATCTTGAAACGTTATATCTAATACTCCTACATGCATATATTTATTAAACGGAC TATATGTGTGAA

GTTAGGTGAAGTCAGTTGAACCACTCCCCTATAACGGGAAACTTAAGTATTATATAC TAAGAGTGTAT

AGACTGGGATGCGTTATAATATGGTAAGGATATTCTTTAAAAGAATTAGACGAATCA ATGAATTAAAA

CCGTTAAAAATTAATCTAACAGGTTAATGAATACTAATAGGGATGAGTAAGTGAGCG GTTATGAAAAT

CCTATTTAAGTTATGCTCTTAAATTATTATTAGTGCGGTAGAGTTGGTACCTAAGTT ATAACTATGCTA

TCAAAATTGAAAAGGTGGAAACTAGGAAGATCGTAAAGATGTTTAATGTCTGATCTA ATAAATAGGA

AATGATTTATGAATCTTAGTGGCAGCAGCCTGTAGTAGTGATGAAGCTCTTGTAATG AGAGTGGAGTG

AAGGGGCATAGTCAGAGATTATATTAACCAAATAATCTTTGATGGAACGCTGTATAC GATGAAAGTCG

TACGTACAGTGTGAAGTGGGGGAAAATCCGGAGATAATTTCAAAGGATTACCTATCA CTATCCGTTAA

TATGGTTAGATGAATATGCGTTTTTAAAATATAATGATACGGTATTTAAAGCAATGC GCCCTGCTTTTA

CAGAAGCAAGTAAAGCTGCAAGCATGAATGATACTCCGTATTCAATACTTATTACAA CAACGCCTAGT

AATTTAGATTCCGATGAAGGAAATTCATGTTATAATCTTATACAAAATGCAGCTAGG TTTGATGAAAA

GATGTATGATTGGTACTATCAGTTTGGTCCAGAATACCTTCAATCATACTTGGATAA AAACTCTGGTAA

TGATTTTATATATATTGAATTTAGTTATAAAGAATTAGGTAAAGATGATGAATGGTT AGAGAGTCAGA

TTCGGGCAATGTTAGGTGATAGACTTAAGGTTAAGATTGAATTATTATTAGAATGGG TTTCTAGTAGTG

AAGATTCAATCTTTAGTGAAGATATTATTGAATCTCTTGAAGGTAATATTATAAAAA GGGAAAATTAT

GCAGGATCCATATATTTATGTGATGGAACATATAAACTAGATGTTATTAAAAATCCT ATAAACTTATTA

ACTAAAACATACGTTATATCAATAGATATTGCCGGAGGATTAGGTAAAGATAATACC GTTGTAACCGT

TATTGATCCAGTAGACCTTAATACGGTAATGGTATTTCAAAATAATAAAATTACTGT TCCGGAATTAGA

AGATCTTGTTACTGATCTAGTGTTAAATTATATTCCAAACGCAGTAGTTATTCCAGA ACGAAACTATGG TGGGGAACAACTGATTGATTATATTATTAAACATAATTTAATATCTAAAAATCTTTTTTA TGTAACAAA

ACAAATAACTACTGAAAAGACAATCTTACAAGAAAATAATGTTTTTAGAAAAAGAAG TAATAAAGTT

AGAAAAGAAAAAAGGGTATATGGTATATATACAACAACTAAGACTCGTGATATAATG ATTAATACTAT

CCTTCCAATGATTGTTTATGAAAGACCCGAATTGGTAAATAATGCTTCCTTATTTAA TGATATTAAAAC

GCTAGAAAGAAAAAGAAATGGTAAGATTGAACATAAGTCAAATCGCCATGATGATAA TTTATTTTCAT

ATCTGGTAGGATTATATGCACTATTATATGAACACTCGATCAGTAGGTTTGTGGATA TTATTGATAAAC

CCGAGTTAAATAAGGAAGATGAATTAGTTGATACCGTAATAATACGGGTCAACATCG TTTAACTAGTT

CTCAAAAAGCATCAAGAACTATTAATAATTTAAGAAAAGTTAGTAAAAAACCAACAA GCAAATCAAT

TATTAATGCATCAATGAATATAAATAACGAAGATTCTAGTATTAATAATTCTATGAG TAAAAAACCAC

GAAGAGGACTAAATTTAGTCCGAAAATATAATAAAAAATAAATTAATTTTTTATATA CTATCCTAAAA

AATATTATATAATAATTAAATATAATTGATTGGAAGTGGAAATTTTATTATGGTTAT GTTAAATGCAAC

TGTAAATGAAGAATATAAACGTGAAAACGTAAATGAAATTATTACAAATATTAGTGA GGATATTATGA

TTGATAATATCTTATCTCAAATAAATGATACTGATATTCAGGATCTTTCTGAAGTAA GAAAATCATTCT

TTGAATACTTTGAAGAACGTTATAACTTTGTTAAGAAAAATTATAACGATGATGATG AAGCAATGCAA

AATTGCCGAGAAGTCTTTGATGATATTTTAAATCAAATTATTAAAGCAATCTCTGAA AAATACAGTTTT

GATCTTTTCTTTTCAGATATCCTATTATTCGATACAAAAGTAGAAATTACTAAAAGT CTATATTATTTCT

TTGTCATCAATATTCGGGAAAATATTGAAAATATGATTTATTATTTTATCATGAAAA ATAGAAAAACAT

TAGTAAAAATGTTTAACACTATTAGTAAAGAAGAAAGAAAGAATTTAAGCTATATTA ATCTTAGTTCT

GCAATCAATAATGATTATACGACAATGATATATCATTTAAGCATGATTATTGATAAT ATTGAAATTCCT

ACTAATGAAGATATTATTGAATTAATGGTTGAAGATAATTCATATGAACTTTATAAC TACGTAACTGTT

AATACATTAGTTCTTACAAATTTCTGCGAAGTAAATTATAATGAAAACTTTTACTCA ATCTTTCTAGAT

ATTATTAAGAATTCTCCAATTATTGTAAGAAATGTTAGAAACTCACTTATTGACTCA TTAAAATAATAT

TAATTACCCTATCCTTAAATAATTTAAGGATAGGGTTTTATTTAAACAATTTTTTAT AAGAAATATTTA

AAGAAGGGAGACGTTAATGGTTGACTAAAAAGATGAGCAGTTTAGACCGAATTAAAG ATTCACTTATT

TTTAAAGGTGAAATATTAGATATATACTTACCAAAATCTAATTTTGATAAAAATCTA TCAACGTATAAT

GGTGAATATATAAATACTATGGGTATCTTTTCATTCATTGAAAAGAAAGCTGGACCT GAAGATAAAAC

AACTAAAGGAACTTTACGTAAACTAGAATTACCTAATATGATTGACTTTCAATACGA TTCAAGTTATTC

TTTTAAGGGAAAATTATCGGATGAATTACCCTCTGACACATACGAAGTTTTTCGACT TACTACAGGAA

ATCAATTTATTGCAAATGTATTTACAGAACAAAATGCTTCTAATGTTAAAAAATTTA TATCGGCTCTTC

ATGGTGGTAATATTCCGAGTTCAGTATCTTATGATAATATTATTAAACTATACTTAG ATACTTTATCAA

TTAATAAAGTTAGTTTACGTAGTCCATCAGTAATTTATGAATTGATTATCTCCGAAT TATGTAGGTATA

GTAAAGATATTAATGAACCTTTTAGAAAGATTATTGCTTCAAAAAATAATATTAGTC CCTATATGTATA

CAAATATTAATCTTAAGAAATTACCATCAATCAATTCTACTTTTGCGGCACTTAGTT TTGAAAATCCAA

ATCAAGCAATTATTGACAGTATTAATAAGAATATCAATGGTGAAAAAGAGAATGAAT CTCCTATTGAA

AGGACTATTAAATACTAATATTTTAAAACAATAAAATATAATCTTAATAAGATGATT TATTTTTATGTT

TATTAAGTTTTTTATAAAAAAGATTATAATGAAAGGAATGAATTATAAATATGGCTA ATGATGCAAGT

TTGACACAACTACATCCATCAGTTTCATCCGTTATCAATGCAAATCAGTCTAATTTT CTTACATCTAAT GGTGTAGTTACTCTATTTGCTGCAGACACCTTTGCTAAAGGTAAAGATGGTGCAATTGAT TTTGTTAGT

ACTAAAGATGAATTTATTTTTAAATACGGTACTCCAGATTATTCCAAATACGGTCAA TCAGCTTATAAT

ATTGTAGAGTGGTTAGAAAATGGAGGTCAAGCATTTGTCCTACGTCTTCTTCCTGAT GATGCTACCTTC

TCTCATGCAATTCTGAATGTACAAAGTAAAGTTGTATCTCAAGGTAAAAATGTTTTA ACTACTGCAGG

AGAATTGGTTAAATTAGATGATGTTCATCTACGTCCTACTACTGCTTTTATTAAGAA AAATAATCGTGA

TAAGAATATGTTGATGTCTGAATTGACAAAAACTCGTTCTGATGAGAATACTGTTGA TGGTTATACAA

ATAACTTTGTATTGCTAGTATATCCAGAAGGTCGTGGAGAAGCTTACAATAATTTAG GTTTCCGTATGA

CTCTTAATGGTTCTTTCGATTCAGCAGTAAATAGTTCTCGTGTTTATAACTTCGAAG TAATTCAATATG

ATTCTGAATCTAATATGACTGTAGTTGAAGGACCATTTTATGTATCTTTCGATCGTA CTGCAATCTCAG

CTTCTGGGGAATCTATGTTTATTGAAGATGTTATTAATCGCTATTCTAAACACGTTA ATTGTGAATTTA

ATGAAGAAAACTTTAACCGTTTGACTAAATCTATTAATCCTAATGTTAACCCAGGAC ATATTGATATTC

TTACTGGTAAATCTAAAGTTCTTCCTTCTGGTAAAGCTGAAACAGTTTATTCCGAAA TTACTCGTGATA

ACGAAGATATTCATATTTCATTACAAAAATATAATGCTCGTGGAGAACTAGTAACTC AGAATGGTAAT

GCTGTGCTTAATATTCCAGACCCTACGGATACTGTTGAAGCAGCATTGATTAGTTTA GATAATGGATTA

CGTGAAAATATTTACAATCTAGACTCTAATAAACTTGCTTACATGAAAGAACAATTC CCTAAACTAAA

AACTGATAGTTCTAGCGAATTTAAATTGGCTATGAATCAAATTATCAATGTTCCAGG AGATGATTCTCA

ACCTAAAACAGGTGAAGTGGTTACGCTTATTAATAATAACTTTGATTCATCTAATCC TAGCAGTCTTTA

TAGTAAATACCTTATTGCTAAAGAAGCTTATATTAGTGAAGATAGTGATGAAAATCT TTCTGCAGTATT

ATCATACGTAGATCGTTTGTCTGAAGTATTGAAGTCTCAATTTATTGATTATTCTAC TAAAATGAATGC

TTCTTATACATTAACTCTTCATAATTCACCAAATCCTCAACTTCCGGCACAATATGC GCTTGAACTTAA

CTCTTTGACTGATCTTCTTAATAAGAAAGATCAAATCAATATCTTTACAGTTGAGCA TCAAGGTAAACT

ATTTGATATTCAAGAAACAATCACTAAATATCGTTTAGGTACTGTTAGTGGAAGTTA TTTGGAAGGATT

GTCATTAATCCTAAACAATGTTGAGAATGAAATTAAATATGTATATGAAAGCTTACT TCCAGTAGCAT

ACAATGGTTATCAAAATGTACCTGTAGAGATTTCTGATAAATTTGATTCATCAAAAC CAGAAAGCATT

ACAAGTCGTTATAACCGTATCTTAGATCTTCAAAGTGATATGCAATCAGGAATTATT GACAATACAGC

AACTAATCGTGATGAAATCACTTCAGTAGCTAATGATATTACTATTGATCTATTGGA TGTTATTAATGA

AGTTACATTCACTTCTAGCACTACAAATATTGAAAGTGCATGTACAACTTCAGTATC TCATATTCTAGA

TAATATCGTTTCTTTCCATTCTGCAGTTCTTACAATGATTACACCTCAAGGTACTTA TGACTTTGATGCA

ATCATTTCTAATGCTAGAACTCAAATTGAAACTGAAATTTCTAAAGTTTCTACATCT AACTCTAAATTC

TTTAATACAAATCTAATTGACTTTTCTAATCCAATTAAACTTCTTTTGGGTTCTGAT GGTTCATTTACTT

ATGACCCAGATAATTTATCTGAAAGACGTGCTTCTATTAAACAATGGTTAATTAAAG CATATAGTGGA

TCAGTTGATTCTGATCTATTGAATAAAGATAAATATCCAATTGATATCATTTTGGAT GCAAAATATGAT

AGTGATGTAAAAGCCGCTATCGGTAGTTTGGCAGCCAATATTCGCCGAGATTTCCAA TTCTTTGCGGAT

GATGCGGGTGGTTCATTTAGTTCTTCTCCAGTAGATTCTCTATCATGGAGACAGACT TCTGCATTCAAT

ATTAGTTCTCTTAACGTTTCAATATTCTCTCAAGATTTAACTTACTATGATGAATAT ACTGGTAAAGAT

ATTCGCTTCACCGCTCCTTATCAACTAGCAAGTAAGATTCCTTACAACGCAGTACAA TACGGATTGCAA

TATCCTTTAGCTGGACCACGTAGAGGTCTAATTAGTGGTCATAAAGCTATTTCTTGG GTTCCTAATGAA GCTGAAAAAGAAAAACTATATATTGCTAAAATCAATTATATTGAACAAGATACTAGACGT ACTAAATT

TGGTTCACAATCCACTACAGAAACTGGTTATGGTGCATTATCTAATATTAATAATGT ATTTACTATTCT

TAAAATGGAACGTGATGCTAAAGAACTTGTATCTAGTTACCAATTTGAATTCAATGA TGAAGAAACTA

AAGATTCTCTTTATACTGAATTGAATTCTTACCTATCTAAATATACAAGTGACCGTA GCTGTGAGTCTG

TTGTAGCTACTGTTAGTGCTTCTGACTATGATAAACAACAACGTATCATTAAAGTAA ATATTTCTGTTA

AGTTTAACGGAATTATTGAACGTGTTCAATTAAGCTTCGATGTAGCTAATTAATACT ACAATATTTCTA

ACTAGAGGTAAATAATTTATACTTATTTTATTTATCTCTAGTATTTATTATAAACAA TTATTACTTATAA

GAGAGGATGACAAACATAATGCTAAAACCGGGTTCTAGTGCTAGAGTCTTTGATAAT GACTTAGCTAA

AGGTAAAAGCTTTTTTACCGGATCAATGAATACACAAGAACTTCAGTTTGATCCATT TGTTACAGGATA

TGCATTTATCCTTTGGACTAAAGTTCCTACTTGGGTTGAAAAATCATTCCCAGGATT CCGTAGCCAAAC

TCAAAAGAATTTTAAAGAATTCTCAGGAATTTCAGATATGGAACTACAAACTGCTGA ATATACGCATA

CTTTTAATAACAATGCTTATCGTTTTAATAGTGGTATTACTAAAAACAATACTGAGT TTACTCTAAGAC

ATCAAGAATTCTCAGGTAATCCAATTACAAATATGTATAACTTATGGGTTTCTGGTA TCAGTGATCCAC

AAACTGGTATTGCTACTTATCCTAAAGAATATAATATGGAGTATGCTGCTAAGAATC ATACAGGGGAA

CTTCTATATATTGTTACTCGTCCTGACGTAAATAACGTAGAACGTAATAATATTGAA AAAGCATTCTTC

TATACAGCAGTTATGCCTACTCGTATTGCATTAAATCATTTTAACTATACTTTAGGT ACTCATGATGGT

GCTGAAGTTGAAATGCCATTTGCAGGAAACTTGCATATTGGTCCATTAGTTGATGAT TATGCTAAAGA

AATGTTACGTAAAACATACTCCTTTAACGCTCAAGGTATGTTTAACCCTCAAGATGG TTCAATTGCTGG

TGAAAATATTGCTGTATTTAATGATAATGCAGGAGTTACTGGTTCTGGTCTAGGAGA TATCTAATTAAA

TTAAATACCTATCACTATATTAATTTATGGTGATAGGTATTTTATATTTTAATTTTT TAGAGAAATTATA

GATATCTAACAATAATATATAAATGTATTTGGTTGTGAATCTTTATTATTTAAAATA ATTTTTTAAATAT

TAGAATAACAATATAATATAATTTTACTTCTACGTGTCGGTATGCAAGCTGGTTAAA GCAGACGGACT

GTAACTCCGTTTCGAAAGATTCGAAGGTTCAAATCCTTCCCGGCACATCTTTATGGA AAGTTGTCTGAG

TGGTTTAAGGTCTCGGTCTTGAAAACCGATGAACGTTTATAGCGTTCCGTGGGTTCG AATCCCACACTT

TCCTCTTTTATATTATGGACTTTTAAAGTTTAGTGGCTTTAAGAGTCAGCCAATTGT TTGTTTTTCTTTCT

TTATTCCATATTTACTTTAGGGATATATCTTAAGGGGTTTTTGATATATCCCACTCC TTTTGACGTGTAG

CTCAATGGTAGAGCATCTGACTGTTAATCAGACGGTTGCAAGTTCGAGTCTTGCCAC GTCAGCTTATTT

TATTAATACCTTATAATTAATTAATACCTTATAATTAATTAATATAAGGTATTAATA ATCCTAATACGG

TTCTTTAGCTCAGTTGGTTAGAGCAGACGGCTCATAACCGTCCGGTCGATGGTTCGA GTCCATCAAGA

ACCATTTCTCTAAAAAAGATTATATAGAGAACAGTAATATTAAATTCAGTAATCTTA TTCTAAGTTAAT

ATGTATATATTAATAAGATGATAATTAAAGAAATTAATTATTGCTGAATAATATTAA ATTTCTTAATAA

ATAGATCAATTAACTTAAAAAATATCATAACGATCCTTTTTAAAACCACACCTTCAA AAACCATGTAT

ATGATTGATCTATTTAATGAAGTCAAAAGTATTCTTGTATCCTCCTAATATATGAAT ATTTAACCATTTT

_{TTTTTTTTTTTTTGCAAGTTTATATTGGTTCTTGCAAACTCTTTTTTCACGTATT ATCTCTTAAATGAGGT}

AATACGTGTTTTTATTATAAAAATAAATATATATTATAATGATGATTAAAATAATAT ATAGATTGGATT

GATGAGACGATGGCATACAATATTGATAACGTAAGGGAAACTAAGGCAAAGGTATTA AGAACGGCAA

TTAATTCTCTGATTGCTAGATATTATGAATCTAATGATCCAAATACTGCACTAGAGT ATTTGGAGACAG CTGCTAAAATGGAGGAATTTGTTGAGAATGACAATTATAATTATTTATTAGATTATAATA TGAAGAGT

ACCCATCTAGTTAGACGAGTGACTAGTATTGATACAAATCTCAATAAATCAGAAACA AATGTTGGAAA

ACAAAAGATTAGATGTATGTATGAAAGAGAAAAGTCTGCATATATTTATAATATCAA AAACAAGAAA

GTTGAAAGTGTTTATAGAAATAATAAGAATATTTCTAAGATCAATAAACCAAACTTT AATGAAGATGA

TATTGCATTAATGCGTAAGATTCTTGATTCCGAAGAGGGTAGTGCTATACATAGAAA TCTTATTGGTTC

TTATGTATACAATCATCGAATTGGTAAATGTGGAGTGATTGTCGGAATTACTAAAGC GCATATGTATTA

TACACTTAGTGATAAGCATAATAATACTAAAACTAATGATACCAAGTTTGTTGTGAG ATATCTAGACA

ATACTATGAACAACAAACAAACATCTATTGGTATCTGGCGTGCTACTAAATGTTCAT TTAGTAAAGAA

ATTTCGGACTTTGCAACATATTATACTAGTTCAGAAAGTACGGAAGAGTATGATAAA GAATATGTTAT

TAATTCAATGAATCGTCTATATGAAATTGAGAAGAATTATACTCATAAATTCTTTGA TACAGGACTAA

AGATTTAAAGAATATTAACGCTAATCATCCAATAATAAGGATGATTAGCGTTATTTT TTTTTTTTTTTAA

_{TTTTTTCTAGATACGTTTATTGCCTTCATAACTATCTTATAGGAATCATATGCTA TCTTTTCAGGAATTA}

CGTTTGAATATTTATTATGGACATCCACTAATTTCTTACGTAGTTCTTCATCGCTAG TATTAATAATTAG

CTTCTGAAACATTCCAAAGATACTCATATGTTCTCGTAATCCACTATTACTAGAATT ATATATTACCTT

ATTAAATTCGATCTTTTTTACTTTATTAGATCGGCAATATTCATTATCAATATTTTC TAATAGTTTATTA

AGGTCACTAATAGTCTTTATACCTTTTATTTTACTAATATCTTTATGATATTCAGAT ATAGATGCGTATA

TATTATTTTTAGAAAATATACTTATCTCATCTTTATTAAAATGTTTGTTTAAACCAT CTTGATTTATAAT

ATTAATTCCATTCCGAATATTTTCTTTATTTCGACTAATAATTTCAGTAATAGTACT TTGTCTATCTTTAT

GTTTCTCAATAAGATTTTTTACTTTACGTAATATTGATTCATTAATTTGTGATTCTA ATAAATCTTTAAT

ATAATTATTATCCATATCTATATATCACCTTTGTCTTTACGATTATATTTATAGAAT TCTATCAATTCAA

GAGAAAGATCACCAAAAATAGCTTGCATTGAAATTCCACCATTGATATTTACATTTT CCATATCCTTAA

AGTTTATTAGTGGGTTAAGGTAATCATAATTATTATTATTATCTGCAATAAATACTC GAATTCTATTATT

_{TTTTTTAATAACCTTAATTAATTTACTATCAAAGTTATAATCATAGGTATCTATA GTTTTAATATATAAC}

GTAGGATCATCTTTAAATATATTACGTTTAGTTCCATAGAATTGATCTATTTCTTTA AATCCGTTCGAAG

CAATATTTCCTACAGCTACAGAAAAGCTATTATATGGTGGTAGATTACTATTTGTAC TATCACTTTTAA

TAAAGAATCCATAACCAGAATTATCATTCTTATTGTAGTCGAGAGCAAATAATATCG CTCCGCCCTTAG

ATGGTGAAGTATGTTTTAGTTTAAATGTGATAATATATTCGTCTGGTAAAGTTAAAT TTGTACTATACA

TATTTTTCCAAATATTATTCTTTGTTTCGTTATCCCTTGAACTTTTAATAATCACTG GATTAGATTTAATT

TTAACATTATTTTGAATTGTTTCTATAATTCTACCATTATTATATGATGGATTATTT GTGATAATTTCAC

TACCGTTTATTTCTTGTATGGTTGGATGAAAATATATTCCTTCAAAAGAATCTTTAG GGAAAATTTTAA

CACCTTTATCATCTATTGTCTTATAATTATATAATAGGTTTATATTATACCATCCAG AGGAAGGAACTG

TGAAACTAGTATATGAATCATTATTTGAATAGCTCTTAATATTAATAGATTTTGTTT TGATATATGCAG

TAGTATCCTTTTTTGCATTAATTATAACATTAACCGTAATTTTTTCAATACTTATTG ATTTACTTTTAATA

ATACCCAACTTAAGGTAACTATTCTTTTTATTAGTATTAAAAATATCTGATCTTGGA TGTAATGTAGTT

ACGCTTTCAGTAGTACTGTCTGTATAAGTAATAATCATTTCATAACCCATACTATCA ATATCATCATTA

TTAAAACTACTTGAGTACTCTAAATTTGTAAAGAATAATCTATTATCTTTAATACGA TTAATATCTCGA

TAGTTATTTACTGAGTCAGCAGTAAAATTTACCGATATAATATTATTCTTTCCTTTT TTTATTGTACTAT CAAGAACATGCACATACCTACCTTGATCTTCATCATAAGAAACAAATGTTCCATTATACG AATTTACA

AACTTATCAAGATTATCATCTCTAAAATCGCTTAATAATTCCATTTCATTAGGATTA AAATCTTTATTA

ATATTTACAATATTTTTTGCAGTATCAAGGTTATTTATCATTAATCGTACATTTCCA CTAAAGTTGTTGG

TCAATCCATATTTTTTACTTTTATCTAAGTATATTTTACCTGTAAATGATTTAGTAT AACCTTTTTTAAA

ATAGTATGATGGTATACTAGTTAGACCTTTATCATCTAACGTAAAAGGATCTACATA TCGACCATCATT

ATCTGTAACTTTACCCATTTCAACATCTATTGATGCTAGATTATAGTTTGCATTTAA TATTTCATCTTTA

TTATCTGAAAAATCAGGAACTGTATGCCATGGAATTGTTTCATTGATATCAGTACCT AATAAATCTTTT

GATTTTTCATTTAATGGATGTAACATATGTTTTTTTACATATCTTGGACTTTGTACG GTTGATTTCATAT

_{TTTTTTCCTGATTAATAATTTTATTGATTGTATTTAGAATAGTATCAGGGAATAC TTTAATTGTTTTCTT}

ATTAAATTTTTCAACAGTATCCATATCATTAACAAACATTAATAAGTACCATAAGTC AGTTGTTTCATA

TAATTCCTCAGATACATATTCCGGTCTATAAAATTGGTTTTCCGATATATCATAATC AATTAAGTTTGA

TTTAAAAATATTTTCATACTTTTTTAACAATGGAAAACCTAATACTATCTTTCCTTC TAATAAATAAAA

GTTAGATATATTACTAAGCAATATTTTATTAACGTTTATTGAATTTATTCCACCAAC TAAGTCAACAAA

TCTTGAACTATCTAAACTATTTCTAGAATTATCTACTACTACCAAAATATATTCACC ACTTTTCAAATTT

CATTATATAATTATATGTTACTATATTCTTTTTTATCAAAAAAAAAAAAAAATGCCA TAGTATATTATG

TAATATACTATGGCATAATAAATGTTACATCATTGGATCATTATTATCTTCAGAACT ATTTTTAATATTA

GATATATTTAACTTATCTTTAGTTAAATCTTGATTTGTTTCGTTAAATAATGTATCA AACTTAGTCCAAT

CAAGAGTAGACATATATATTTCTGAAGCTAATTTTTTCCTAAACAATCTTTTCTTAT TATCGGTATCCTC

ATTTTGTTCTGACTCTGTGAAATAATTACCTACAATAAAATCTATTGTCTGTGAAAT ATTATTAATTTGT

TCATTAACATTAGCAATATTCATAAATACTGGTGTAGGGAAATTAATAGTGATTTCT TCAATTTTTACT

TCATCTTGGTTTTCGTTATAATCTTTTTCATCATTTGTTTTGTTCTTATCTTTACGA TCTCGTTCACCATA

CTCATAACGATATAGCTCTTGAATTATCTTAGTAAAGAATTTACTAAACGTTTCTTG ATATCCAATAAC

TCTTCGAACAAAATTACTATTCTGCATTGATAGATTTCTTGCAAAATCAACTTCATT AGTAGCATCAAT

ATAATTAATTGGAACACCTGTTCCATTAACTGCCGATTTCTGTAAGAATTCTAAGAA ATCATCATTAAT

ATCAGCTTGTATACCTGGAATAACATCAATATCGAAAGGCTTATCTCCATTAACTGT TGGAATAAATGC

TTCTTCTGTAGCACCTAAAGTTTTAAGCATAGTAGATACACTATTTCCGGGACCAAT ACTATCCATTGA

AAATTCAGTAGTCTTTAAATCTCGGATAAGTTCTTCAATAGTTCCCTCAATATCAGA ATCCATATCAGA

CTCTACGTAATATACTCTTCTATCTCTACCTTGATTAATTTTTACCATTAAATTTGT AATTAATGTAGAA

AGATACATTTTAGGAAAAAATAGACTATTATTTAATCTAGATACACCATACTCGCTA GTGCTATCTAAA

GGTAGATGATACACCTGATTTGGTTCTAAGAATGTTATAGATATATCTTTATTGATA ATATAGTCTTCT

CTGACCAATCTATATATTACATCTTTAAAATCTTGGTTATCTTCTAAAAAGTCTTTA GATATTTTATCAC

TAATTCCTTTTACAAATATATCAGTAATTATCTTGTATTTTTCATTACTAGTCACTC CTGAACCACTCTG

ATTTGATCTAGAGTTATAATACATTGTAATATCTCCATTAACACTAGAAGATCCTTG TGGGGCATTACC

GTTAAGAGTTCCTGCAATAGTACCTAATATTGAACTACCTTTAAATGAATTATTGCT ACCATTCTTTTC

AATATACACGTATCCTAAACATACTCCATCAATAGATATTTTAATGATATCTTCCGG ACTAAATATTTT

TAAGTAAGATCCGGTAATATTTAGATTTTGAATGTCTTTAGATTTTTTACTTGCTTT TCGAGATTCAGAT

ACAAGATTTAGAGGGTCTTTATAATATTTTACATTTTTAGATATAGACTCATATACC TCATTAGCAGTA CTTTCTACTAAAATCTTTTCAATATCTTTAGGATTACTTTTAGAAAATCTTTTTCCATTT TTAATATTAG

ATGATTTAAATTCAATATTTTCATCATTCATAACACTTTCAATAAGATTTTCAATAT TTCTATGATCCAC

GTTAAAAGATTCATTTAGATCATCTTCTTCAGAATCAATAAAGAGATTATTGGTATC TAATTCATTAAA

TTCATCTTCAGAAAGAATACTTTTAAATTGGCTTTCTAGATCGGTAACCATGATAAA CAGATCACCCTC

AATTAATGTATTCCGAATAGAATTTCGAATAACTGTATTTAGATTATATTTATCAAT CAACTTAGACAT

ATTACCATTGAATTCTTTTTTATCCGTCTCCCCTAAGGTAGTATTTTCATTATTATA ATAGTATGATATT

GATTGTTTTGTTACATCGTCTGGAGACATAATAGAATCTACATACGTATCAATAGCT GTACCCAATTCC

GGAAAATACTGAGATATTAGTCTAAAATCATCATATCTTTGCCATCTTAGTTTTTCT TCAGCAAACTCT

CCTGATGAGAAACTACTTTCAACTTTTTCCTTAAAATAATTGTTGTATATATCAGAA CTTTTTTTATTTT

TCGTATTTTTCATTCCAGTATTCTTAACTTTATCTCTCTGTATGTCGGAGATAATAT CAATTATACTTCTT

CCTGAACTGTTATTATTACCGTTTCTTCGTTTAATCTTATTTAACATATCATGAAGA TTACTTAATTTAT

CTTTTGGTATATCTTTCTGGTTCATAATACCGTATAGATTTTTAATAATGTTTGCAT TATCTGCCATTAA

ACTTATCCACCTTTCTAAATTGATGAAAAAAAAAAAATATCATAGGAAAAAATTTCC CTATGATATTC

ACTAATATTTATTTCATATCTACGAATATATATGATTGTTCCATAATATAAGTATCA TTACAAACTTCA

ATTACAAGCATTTTTAATGATGAATCCTTGTTATGATTAAAGCATAATATATTTATA GATGGATGTTTA

CTATATACTACTGGAATATAATCACTAAATTTTTCTTCTTTATATTTTTCATATGCT TCATTAATATCTTT

TGGATAGTTCAATGATCCGAGATTATCCTTAATATTTGTAAAATAAGGTATTTCAGT AAATTGGTCTAT

ATCGACAATTAATGGTTCAGGATTCTTTTTACGAATATACTTAAAGCCTTTGATAAA TTTAGTTGATAC

GGTAACACTAATATAATCATCTAATTCAGGTTTAATCATATCATCATGGATAATAAT ATTATTATTATC

_{ATTTTTATCAATAACTATTGAGAATGTATATTTATTGTCAAATTCAAGTAATTTT ATTACATCATCATCA}

CTAAGCGTTATCTTTGGAATATTTAATGAATTTTCACTAAAAGAATCTAATACAGGA ACAATATGATCA

TTATACGCATTAATATCTTTTTCTTCTAAATACCATTTAATAAAAAAGTCTGATTGT CTAATAAACTTTA

TATAGTTATCGTTATAGTCTATTTCTATAGAGACAATTTTATCTGATTTATTTTTAC GCATTTCAAAAAA

TTCTATCATATGAATAGAAAATGTATTCTTTTGCATAAAATCATTTACTGTTTTCAT TATACCTTTTTTA

TCTAGTTTTCTTTCAATAAAAGTAGCATTGATATACTTTGGTAGTTGTTTTAGTAGT GCGTCATCGTTTA

GTGAGGGAAATGCAAAACCATTATTAAAAATCAACCTATCCCCAACATTAAGTACAT TCCTAAATTGA

TCTACCATTTCTTCAATAGAAACTACAATTTTTTGAGCTTCATTAGGATCATCTACA ATAACTTTATTAT

TTTCTTCAATATACAACTATAATTCACCTACTTCTTGCATACTTTCAGAATCTATTG ATTCTCTAATCAT

ACCCAAAGCATCTTTAATATTTGGTAGATTATAATATTTAATGCAAAATTGTAAAGG GTTATTACTATT

ATAATCATCAATAAATGATTCTGTAATATTCTTATTACCTTGTTTAAAAGTAATATT TCCGATAAGACT

TTCAGGACTAATATTTAACGCCATAATAATATGAGGGTATAGTGCAGTTAAGTCAAT ATCGGTTACATT

ATCGAAAATCATATTTGATTTTTTACCCATAATATCAATACCGATTGGATGAACTTT TGATGAGTCTGC

TACAAACGCACCTTTAATTTTTCCATCAATCTTAGGATATAATGAACTATGATTATT ACTAATTACAAA

CCCACCATTATTATAAAAGATTTCTGTAAGGTTTCTTAAGCATATTGTTTTCTTAAG TGCTTTTGTTATT

CGAGTATGTGTTAACGAACTAATTTGATAAATTAGATCTAAGAATTTAGTTGCTTTT TCGATCATCATT

AAGAGAACTGTATCCTGAATGTTATATAGAATGAATTTATAGTAGTTTTTAATATAT ACGTTAGTGATG

TCTCCGTCACCCTCTTCAAACTCATCCTTTTGCATCCCTACTTCTTTTTCACCTATG TCGTTCAATTTGTA AGAGTCTAAGACTCCCATAGATAGCGATAGGTAAGTATTTGATATTATCTCCAACTTTTC CCCCGCTTC

ACACCGTACGTGAGACTTTCACCTCATACGGCGTTCCATCACTCAGTTTATATTGTC ACCGATATATTA

ATGACAATAACTAGTCGTTAACTAAGTTTCTTAATTTAGTTAGTTGTGTTTTATTTA CCCCGGTAGGAA

AATCAGTACTATAGTGAATTAGATTATGTGAATAAACAGACAGTAATACAAGATTAT CAAAACTATTT

GACCCACCTTTTGATCTCGGCTTTTTATGATGTATAACTAAGTTATCTATTCCTATT TTATATAATGGTA

TATTAGTGATAGGATCCTTCTTCTGTTTTTTAACCAGACCGGGAATATACATTTTAT ACCTTATATTGGG

AAAATTAGAACTATTTGTAAGCATATTAATAAATTTTAATATTAACTCATCGTTGTT CTTAGTTTTCATA

ATAGGCGTCCAATACTGTTTATTTATGAGATAATCTTTAGTATTTTTACTGGATTGT TTCCGCCACATCC

ATGTATTAAATATAATGTCTTTATACTTATAAATTTCAGTATCAGGTTTCTTATACA TTTGACTTTGTCG

ACTCCAACTATATAAAATTCCGTTAACTAAGTTAATATAAGCTTGCATATTAGTAAC TAAATTAAAATT

ATATATAGTTCCCAATATAATAGACATTACCTTTTGATAATGACCTTTTCTCAGTTC AGACCTTAATAA

_{TTTTTTCTGATTATACCAAAACTTACTAAGATTTTTAAATGAGATCATCACATGT CCACTTGCAAATCG}

CATATACTTAAAACCTACAAAGTTAATTACAAAGTCCTGACCTTCTTTGATAATGAT TTCACTAGTTTT

ATTCCAGTTTAAAGAAACTTGATGTTTTGTACACCAAGAATCTAAAACAGGTTTAAA TCTTTCTACATC

CCAAGGATTCGGACTAATTATTATAAAATCATCAGCATAACGAATCATTCTTATCTG CATTCGATTACC

AACGGTTTTCAAATATTGATCTTTACCTTTTCGCCTATAATATGACATATTATAAAA CTTATTATAAGG

ATGTGTTTTGTGAAATTCAGATCCATTAGAAATAGCCTCATTATACATGTTTAAGTC ATTGACTAAGAT

TTCTAGATCATGTAATAAAACGTTAGCTAGTATAGGACCAAGTATAGAACCTTGAGC TAAACCAATCC

CTTGATACTTTGTGTCTTTAGTATCTATAGACATAAGAAACTTTATAGATCTTAGTA GTTGCGTATCTCT

AATTTTGTGATTATACCTTAATTTATCAAGTACTATATCTAAATTAATAGTATCAAA ATACTTAGATAA

ATCACAATCTAGTACTGATCCATTCTTTATTTCTTTAGTGTTATTTACTAAAGCTGA CATGGCATGTTGA

GTTGAGAGATTACGTCTAAAACCATAAGAATCAGGATAAAATTGATATTCCAAAATA GGTTCTAAAAT

ATTAAGAATACATTGTTGTGCTATTCGATCTAATATATTAGTTATTCCAAGAGTTCT AAACGAACCATC

CTCTTTTGGAATGTCAACAAGTCTTGAATATAGTTTTATATCACCTTTTATTCGTTT CAATAATAGGCTT

TTAATATCTTTGTAATCTTGTTTTAGTAAATCATCTAAAGTTTGACCATCTGGTCCC GGAGTATTTCTTC

CATCATTAGACATTATCCGTTTAATAGCATATTGAATATTACTATCTTTAATAATAT ATCTAGATAAAT

GCGTAAAAGATGGTTTACCATTTAAAACATCATTATACAATTTTATTTGGATTTTAT TGAAATCAAAAT

ATATAGAATGTAAACTTTTTGTGTCTATATTAACACACCTTCTTACAAAATCAAGCT CTGAATATAAAT

CAGGCAATTATATATCATTGTTTTGAGTGACTTTGGGCTTTCCCATTAATGATACAT TACATATCATATT

ATCGGTTTCTACCCAAACTTTCAGTCTGTATTCATTTAACTTCACCGTGACTAGCAG CTAAACCGTTAA

ATTAATAATATAAAATTATCTACAGACCTTCCCACGTTCCCTACATCATAGAATATA GTATACTTAGGT

TCTTCCTCTAGGCTCTGTGTGATTATAGAAATAATCTGGTTCCCATTATATACCATC CATCTACGCAAC

AAACAATACGTATTTGGAACACAAGTTTACTAGCATTTCTACTAGCACATACCTGTA CATTCAGAAGTT

CGTCAGTCTTAAAAGACATACTAACCATATATACCTCCACCCGACCCATTTGAGAGG ATTGTTTACCCT

TTCGTCAACTTAATGTTACGCTCTAAGTTAGCCGTCTTCACCCAGCTTCACACATAA ATATCACTACTT

ATGCATGTGGGAGTATTAGTGTACATCTGATATAACTTTAGGGAGTTATATAGTGTA TTTGATGTAGAG

TTATTCAATATTATTATAATACTGAACTTTAGACACGCCTATGTGTATCATAGACTT TCTCTAAAAACA TGTCGCACGCTTATTGATATTGGCATATAACGCCATTTGATCTAAATATGTTGTATATCC AGCTACTTC

ATATATGGAAGACTTATCTGCAGGATTATTGTGTTTTTCATCCATTTTATGATATAC ATATTTATATTTA

AAATCATCAGGACACATTAATTCTTCAGGAATCGCATTATTCTTTAGAATTCGATTA TATATTGTGATA

AAGTCAAAATCAGCATTCCACGCACTAGCAAAGTCAGGTCGATGAACTTCATTGATA TAATGAAAGAA

ATCACTAATTAAATCAATTTCTTTATCATATTCATAAATATTAAACGTTAAGTCTAA ATTATATTCTTTA

TATTTGTTTTTTAGTTCATCCAATAATTTAGTTTTATCCAACATTGCGTCTTTATAA CCATCATGATCAT

ATTTTAATGCAAAAGTTTCAACAGTAAGATTCCATTCATTTACAAGTGTAATAATAT TAATCGGAGCTT

CTGCTTTCTTTTGATCTGGAAATCCAATAATATTTTGAGTATCTACTTCGATATCGT AAAAAGATTTCTT

TAGTCCAAAAAGATTATTATCAGGAGCATGTTTTTCTAAATAACGATGAATATAATT ATCTTCAATATT

CTTATCAGAACCATGAATTCGATAATCTAAATGCATTTTTTTAAGATTTCTTCTATC ACGAAAATCTTC

AGACTTCATAATATTATCATAGAATATTTTTACGCTAGGATCTTTTAACTCTGTAGC AATACTTTTAAAT

ATATCTCTGTTATAACATCTTACTTGCCTTACTTTTTCTTTATCAATATAGTTTCTT ACAACATTATCTTG

AAATTCCGGTTTAGTAATATAATAATCCATCATTGGTTTTTCAATAATATGATGTTT TTTTGTACCGTCC

TCTTCTTTAGTGACCATAATAAGTTTATCAAAATTATCTACTGCACCAGAATTTCTT GCATCTTTCTGGT

TTAAATATGTTGTCTTAATTAGTTGACCCAAAATATACACCACCATCTAAATTTATA TAATTCCTTGTTA

TTTTTATTTTATAAAATTATATTCTAGTAAGATTAATGATATCAATAACTTTGTTAT ATCCATCGAATTT

AAATAAATCTTTTCTACTTATAATAATATCTTTATCTAGATTTTTAGCATATTTAAG AAAGAATCTCATA

TCCATATCATGATAAGTACTAATCATTTCCCATTTTTTAGAATAATTTTTAGGATTA TTCTTCATATGCC

TATCAATAAATTTAGTGGATAATTTTTTTTCTTTTAAACATGTTTAAATTAAAATTA TTACTTTTTCTAC

CGTTTATTATTGATAACAGTTTTTCTTCACTAATATTATTATTTTCCGCCATTACTT CTTTTTTGTCTAAC

GGTACATTTTTGAAATCTAATTTATCTTTATTATAAGCCAATAATTTACTATTTTTA CTAATAAGATCAA

TATATTCATCATCCATGAAAACTGATGCGTTTGTTATAAAGTTTACAGTATCGTTAA ATACATATATTT

TTTCTTTATTAGATGTATCACTACTACTATTATATTTACATATAGTATTTATTAGAT ACTTAATAGATTT

AATACTATTAAGAGTATCATATTCCGCAATACGGAACATATATTTAAATACATAGGA AATATAACCAA

TACTAAGATAATCAATATTTAACATTAACGTATCTATGAAACTGCATAAGACTTTAT TAATATTCATAT

TATTTTTCATATGACTTGACTTGATCATTAGATTAAGATGAATAATAGGTTCCACAT CTTCGCTTTTATA

TGATTTATAATATTCAAAAATTTGCGGTATAATATAATCGCATAAAAATTCTTCATC TATATTCGAATT

AGATAAAATAAAATTTATATTATCGTATGAATATTCCATATAGTCACGAAATAATAT TCTAATTATAGA

ACTATTAAATTCCATAACTGACCGCACTGAAAGATAAGAATTTTTACTATTTACTAT CTTATCAATATT

CTTTATAAATATATGATTAGGTATTTTCATTTCATAATAATCTATATTATCAAAATT TTTTATAATAAAG

TCAATCATCTTATCAGATATTCGGTGTCCGTAAAATGATACTAAATCTTTGATAAAT TCTTCGCTGTATT

CATACATATATTTATCTAATTCTTCGTTCGGTATACTTATATAATTATCTGTAAATC TTAATAGTTTATC

ACCCAAATTCCCATTACTAGGATCAATTTCTATTGTAAGTTTCTTCAATATACTTAC CAACCTTTCTATA

ATTATACTAGCTTTAGATCAATTACGCTTTTTTCAAATTCATTTAAATGTTTAGACC AATTGAATGATAC

TTCTTTATACCTATTAATTTCATCAATAGTCATTAAGTTTATTGTATTAAAATCCAG CGATATCAATGAA

AATACTTTATTCTTTAATGAACCGATAACATTTGTATTTATAAGTATATTATAAATT TCATAATATTTTT

TAGATATATCTTTATTCATTTGTAATGAATTTTCACTAATAAAATTTCCACTATCTG ATATCACATAATC AATAAATACTGTATCATTTATTATATTAAATATACTAACCGGATCAGATATGTCACGCAT TATATTAGT

CAATATAGATTCAATATGTGAATTATCATTATTACCTTTATTATACTGATATAATAA AGGTAATATTTC

TAAAACAAATATAGTTCTCTTAGACTTCCATAATGGAGGCTTATTTAAGTATAATGA TACTTGGAATTT

ATCATCGATATCATAATAATTCTTTTTTAGTAAATCTATAAATGATATAATGAATTC ATCATTATCAAT

AATCTTTAGTGATTTAATTATATTATCATATAAGTTTAATTTTTTAATTATCTTCAT GCTTAATTCAATA

TTTTTAATTCTAAGTATGTTCATTATAATATTGTCTGAATTTGATTTAAATATACAT AGACTTAGAATTT

TTATATAATGGAATATATACATATAATATCACGCTTCCTAATCATTCTTGCTTTTCA TTATCGATTACTA

AACTATGATTTTCTAAAGAACTTAGCCATGGATCATAGATATTATTGAATCTTTCTT TATCGCTAATAT

CTTTAGTAAATATATTTAAGAATGATTTTTGATATTTCTTATCATTATCAAACCATG AAGATATAAACT

CTTTTCCACTTTCTTTACTTAATTCAGTTAATGTAGTATATACTTGGATTGCAAAGA AAGAACTTAATCC

TACTGCATCAACATCTAAATCATTATGTGAATCGTTATCAATAATAATATAGCGATT ATCATCAACAGG

AGTATACTTATTCAGTGCAATCTTTTGAAACTCAATTTTAATATTACCATTAAAACT ATATTCACCATC

AATATAATTGTTAATAATATAAAAACTATTTGTAATAAGTTCCTCAATACATTTATC AGCTTCAGCAAT

AATTAATTCATTACTATATTTTTGTAAATCTTCATAGTTTTGAATTCCTAAGGATTT AAGTCTTACAGCA

ATAAATCCTTCAGTAATTCCAGATAAAGAGATTAAAAATTTTGCAGGATTCAATGAA TATACTAATTT

ATTAGTATTATTCTCAGTAATAATTTCAATACTATATGGAATTTCCATATATCGTTC AGAATTTTCAGTA

TATGTGTTACTGTCTTCATCAGTAACCACCCATTTTTTTCTAGTTCTTCTATTAATT CTAGAAATTTTATT

TTTCATTTCACCTACATTATTGCTGTTATTTAAGCTGATATTTACTAAGATAGTTTT TACATTATCGTGA

GAATTAATAATTCTAAAGTCATAATTATTTTTTCGAAGATCACTTGTAACTTTCGGT AATTCATTATTTT

TAACATCTAATTTTACGCTAAACATTTTTATCATCCATTCTATTTTTATTTTAACAA TAATTCGACTACT

AATATTAATATTAGTAGTCGATATAATTTATTTTTCTGCATTAAAAATAATAGTTTT ATTTTCCATAAAT

ACAGTATCTTCAATATCAATGCTTGGATTCTTCGTTAAAATTAAATCCACGTCAGAA GTATGGAATTCA

TCATTATGGCTAATCACAAATATTTGTTCCATATTTAAATAATCTGTTTGTAGATCC AATACTTCCATAA

ACTTACGTCTATTATTTGTATCTAATGTAGCATCAACTTCGTCTAAATATATAATGT TATACCCTGAAG

ATACGGTTTCAATCATTGACAATGATAATGATAAACTAGTGATTGCAGTTTCACCTT GAGAACTTAACT

TAATATCTGAAAGATCAGTTCCGTTATCTTTAAAGACCCTTATAAAGAAATCTTTTT CAGTGATATCAA

AACGTATACTAAATGATTCACCGTAAGCAACTTTTAATAAGTTATTTGTATCAGACG CAATCTTTTTAA

GATAATTATCAATAAATATTAATGGAATACCTTTCTTAGGATCTAATGATTCTTTAA TAGTTTTAAAGT

CATCATATACTTTTTCAATACTAGATAGTTTATCGGTAATATTTGTTGCAATATTAA GTCTTTTTTCATT

ATCTTCTAATTTATTCTTAACTTCAGATAATGCGTTATTATTAATATTGATAGACGT TTCAGTATTATTT

AATAGATCATTATTATTTTCTAATGTTTTTAGTCTGGATGTAATATCATTATAAACT GAATCGTATACTT

_{CTTTTTTATTAAGAATACTTTCATAGTTTGATCTCAGATCTTTAAGAATATTCAG TATATCCAATCGTTT}

AGATACTGTTTTAATATTCTTATCATATTGATCTATTGATTCATTATTATCTTTAAT ACTTGAAGATAAT

TTTTCTTCTTCCAAAGTACTAGATTTCAATAGTTCTTCATACTCATTATATGATTCA CGCATGATATTGT

AATTTTCAATAGACCCTTTAATATTATCAATAAGATTGGATACTTTGTCTCGGTTGT TGATATTATTAAT

TAGATCAATATATAAATTAGGTAGTTTTACAAGACTATTTTCAATATGATCACGGTT TGGTAAAAATAA

GTCATCCTCATTTAAATTAATAATGCTTGCAATATTACGAATATTATTAAATTTAGG TAGAACTTCTTG ACGATATTTATCAAAATATTTAATAATATTTGACAAATTACTGATATTATTATTAGTTTC TATTCGATCT

TTTTCTAAATTACTTAAGGTATTTTCTAATTCATCCAACTTAGGATATTCATTCTCT TTATATTCTAAAG

CAATTTGAATAAAAGGACAACTATCAATATTACATGCTTCAGGTCTTCTATCTAGTG TTGTTAGTAAAT

TAGATCTACTATTAATATCACTAATATTTTTATTGACTTCCAGAATTTGAGATTCGA TATCATTCATTTT

GGAATCATTAGATTTAAACATACTTAGATAATATTCGTAGTTGTCAAAAGTAATATT ATCGTCTTCAAA

GTAAGTACTTTCATCCATACTCATAAGATTTCTTAGAGAGTCCAGAAGATTACCAGT TTGATGAATACT

ATTATACATATTATTGTCATTCATAATAGATTCAACATTTTCCATACTAGTTTCATT CAATAAAGAATTT

ATATTCTTATTAACTTCAGTCAGATATTCTTCATTTTTTTCTAATTCGTCATAATAC TTTTCAGGATTAA

ATTCTTTAAACGAATATATTTTATTACGGTAAAGACTAATATTTTCCCTAATTTTCT TTAATCGGTCTTC

AGAATCAGTATTTTTTTCCTTTAATGAATTTCTCGATGTTTCTTCTTTGATTAATTT TTCTGTAAATTGTT

GATGTTTATTATAAATATCATCACTTGTATATTTTTCTAATGCTGGAAATTGAGAAT ATATATTCTGTAA

TCCTTGGTAAGATTCATCAAGACTCGTATTAATTGTATTAATAGTATTATTAAATTG GTCAATCGATTT

ATTAATATCTATTTCATCAATAGGTAGATTTAGTTCATTTAATTTTTCTTTAATAAA AGAACTATCCATA

TCAATATTATATTTAGTAATTGTTCTTTGTTCGTTTAAACGTTCTTTTTCAGATTCT AATGATTTAATATT

ATTGGTTAATTCTTCTTTATTTTCTTTTATAGTATTAATATCATCATACTTAGAAAG ATCAGAATTTAAT

GTCTTAAGATTTTTATCTAAAAAAGATAATTTATCTTTAATAACATTAAATCTTTCT AAATAATCATCC

ATAGAAGGTATAAACTTATATAAATAATCCTTACGTTCGGCAGTTTTATAATCAATA AAGTTATTCATA

TTATTACCTAATCTAGCAACTGTCATATAATCTTTAGTAATTCCAAGCTCAGTACTT ACAATTTCTTCAA

AACCACGAATTCCACCATTTTCATTTAATTCCGTACCATTCTTAGAAATAAATGACT TATTATGAGAAG

AATTATCACCATAATAATGTTTAATAATATACTTATCATTATAATTAATATAATGAA TTTCTTTATATCC

TTTAGTATCTGGAATAATAATGTTATTTCTAGAGTCATTTGTACCACGGTAAGGATT CAATGCGGAAAG

AATAACTGTTTTACCAGAACCATTAGAACCAATTAACATAATTATTTTATTTTTAGA ATGGGAGAAATC

AATTTCAATTGACTCTTTTCCCATTCCAGCATATATTCCGATAAAGTTTACTAATTT TAAATATGTTATT

TTCAAGATATCACATCTTTCTAATTATTTAATCTTTTCTAGACAAACTAAAACTAAA TTTAATCTTATTA

CTAGCGGCATTATAAATAAAGTTTGTAATTACATCGTTAGGAGATTCATTATTCTTT TTACATGACTTA

ACAAAATCTTCATAAATATCATATCTACAATTTAGTAATAGCGTTTCAGGAATGAAA TCAATGATTTCC

ATATTCTGAATATTCATTTCTTCAGTAATACCATTATTATCAATATAATTTAGTATA AATAATTCAATAA

GATTATAATCAGAGTTATTTAAGATTCCTGAATAAATTAGATCTTTTTCACGATTAG TATAATTATCAA

TATACTTCTTAGGAATAATAACCCTAATATTTTTTCTAGGTTTATCAAAAATAACTA AATTGATCTTTGT

ATTATCATGACCAAAAAGATTATTAGATTTTTCATAATCTACAACTTCTGTAAATTG CTGATATGACTT

ACAATGATAACAGTTAATTGTTTTGATATGATCAACCGCTTTATTGATCGATACTTT TCTTTGAATCATT

ACTTTATTACCACAATTGTTACATATTAGAGTACATGGTTTTGTATTATATAATGAA TTTGCGTTATTTT

TTGTCATGAGAAATCACCCATTCATCCATAACACTAATATAATCTTTATTCTTAATA TCTAGAAATTCA

TTATATAATTTATCAAAATCTGGATAAAATTCTTCTTTTTTACTTTTAACACGATTA ATAACATCATTAT

AATTTGGTGAAAATAATAGATCTCGAATATCCCTAAGACTATGATACGGCAAATTTT CTTTCTTTACGC

TATTATACATTACTTGTGCCATGTTCATACTTCTTTCATGATTATAATCAATTTTTC GAATAATTCCAAA

TTTTCTAGTCTTCAAATCAAAGCAAACCATATTTCGAATATGATTATTGTACTTAGT ACTATATAACAT ATCTTCTTTAACTTGTTCTGAAATAAAATCATTAGTTGTTAGTTTAATAGGTGCTTCTAA ATCTTTTCTA

TCCACTACAATTTTATTTTTTTCAGATTGATAATAATTATATACGCCATAAGAATCA TTTTTACCATAAT

TCGAGATAGTTCTAATATTAAAAACCGCTCTTAATAATAAATTATCAGTACTGCTAA ATTCATATGATA

ACTGTAAATTGAAATCTCTTGCATTTTTTTCCACATCTGAAGCAAACTTTAAAAATT TTAGAGCTTCAC

CACTAATATATGATGTAGTAGTTTTATCTCTAGCTTCATTATATCTATTTAAGTTTG CATTAATTGTGGA

TCTAATTATCTTTGATAATGTACCATTTACATCATTTACATTAAAATTTTTCATGAA AATCTCTCCATTC

TATTTTTTATAAATATTCATAATTGAGAATAATTCTTTTATTTCTTAAATCACTAAT ACGATCAATATTG

ATTCCTAATCGGTTACAGTGTTCTAAGCTTGAAAGAATTCTAATATCTTTATTGATT GATTCGATATCTT

TTATTGTAGTATTTTCTTTTCTGGAAGCATATAATAAAATTGATTCAGGGTCATTTG AAAAGATATTTT

GATTGATCCATCTATTATATCGATTATTAATAATATTGGACGTTGTATTCACAGTAG TAATAGATTCTTT

GGAATCAATATTTCTTACAATACCTACTCTTTTTTGTGGAGAATTATAAGTAAAAAC AATATCGTTACT

AATACTTTCTGGAGAAACTATTCTGCTATTATTAACAGTAAATTTACTATTAGTTCT ACGTGTTAATAA

TTTATAACTATTCCGTTTATTTACGTTATAATCTAAATCATCACTAATCTGAAATGA TACATATGAAATT

AATCCACCAATATTATTAAACGCAGGAATTAATAAGAGATCACTATATTCAGATGAA ATCTTTCTTAC

GTTATTATCAATACGTCTTTTAATTGTTTCTAATGCTGAAATCATTTCCCCTTTAGC GTATAATTTATAA

TACTGCTTAATAAGAATGTTAATAAATTTGATTGTTTCTTTAATTTCAGTTGTAGGA ATTAATAAATTAT

GATAATTATTATTCCTATAAGTTTTTCTTTCTTTAATACTAGTTGACATTAAAAATC ATCCTTTCAAAAT

TATTATTATAATGACTATGTAATATTGACATAAATTAATTCTCATGTCATTACATAG TCATTATAATAA

TATATAAATATAGTTAAAGTTGAAAGGTAATTTTTTATTCTTCTATTTCTACATAAC TGAATTCTGAATT

ATCAGAGAATATTACGCCTACTTCATTATCGTCTTCATCATAAAGAGATTCAATTAT TCGGTTATTAGC

TAAATATGAATCAATTACTTCATTATTCATTTCATTAGAAGAGTATACTGTTTGATC TTCATCTAAGAA

TATTGGTTCTGAAGTATTAATATCTACGCACATTACATATCCAATACTTTCTAAATA GTCCACAAAGTT

CTCGGAATCATCTTCAACAATTACCACAGATTCAGTCTTTTTCCCTTTTTCGTTAAC CGATTTTTTAGCA

TCATTATTCTTAATAGCATTTAGTCTTTCTTCAATGAGTTTATCATAATCTTGTTCT TCAACTTCATTTTC

ATTATCTTCGTTATTATCATTTTCTAAGTTTTCATCTACAACTTTTTGAAGGTCTTT TCGGTTTGTATTTA

ATAATTCATTTACAATTCCTTTAATAATTAAACTTTGATCCCCATTAATATCGCTGT CTTTATTATTAAT

ATTGTATTCTTTAATCTTAATATCTGCCATTTTAACTTTAAGATCCGACATTGCTTT AATTAATTGCATC

TTCATTGTCTTAAGACTAATCAGGTTAGATGTCTGGTCCGTAACAAACCTTGGGTCT GTCTTCATTCTA

GAATTTTGTGCCTTACTTCCCCTATCAAAATAACCTTCAGAATAAGTATATAATTCA TCAATAGATGAT

AATTCTTTTTTAAGCATATTATATTCATCAATAAGTTCTGGATCTATTGAAAATTTA GGTTTATTTTGTT

CTTCCATATATTTAATTTCACCTACCTATTTTGTAAGAGTATATAGTGATAATACTG CTTCATTACCAAC

TTTACTTATCGATTCACCTTGTTGGGATAATATATTTGTTTTTGCATTAATCAATTG ATCTGCTTCTTTAT

TTGCTTCAGCACTGAATACCCCACGAATTGAAAGCGTATCCCCATCATAATCAGCAC CTAGAGCAGCA

GTTAATGAGTTATTAATAACTAATGAATCAGTAAAATAATTTTCTGCTACTGGATAG TCTGGAAAAAT

GATTGGATAGTTTTCCAGATATCTATCTTCAATTTTTCGATATTCAGTATCATTAGT GCTTAGCACAACA

ATCTTTGAAGGGAAGATGCTTTGATAATTATCTACTGGATATCGAGTACAATACACA TGTTTATCAGAA

GTAATATCAATAGCTGCAATATACAATAAATCTGTTATTGTAAAGTTTCTATCAAGA TCAGTATGAAAT ACTTCTACTGGATATTCATTACCTTTGTCGTCTTTAACCGTAATTGCTTTAAATCTAGCA GGTATATTCT

TAATAAAGTTACTTACTAACTTATTAATATCTTTATCGGTAAATTGATTTTTTACAT TATCAATAAAGAC

ATCTTCACCTTTTTTATTCTTTACATTTGAAAATTCTTCAATATGGATATCAATAAA GTCATTAATATAT

TTTACAAAGAATGGAAAGAATAATGCACATACCTGACTTAATGGAATGCCTACGGTC CCAAATTTTAT

TTCTGTATCGTCCCATCTATTTGTGTTTGATCTAGGAGCAGAGATTACTGATCTAGT TGCATAATCAAT

GGATTTTCCTAATAGACCCCTATGCACTAAGCCGTTCTTACCAGAAATATAGTCGAT AAATGTTTTATA

TACGTCATATATAATTGTCTGCATTTGAGATTCGGTATTTGTTCGGACAAAGCTAAA CGATGATTCACC

ATCTAGACTAGAACCAAAACGAATTAGTTTAGCGTATAGATCATTAATCTCATCTAC GTCTGCTATTCT

TCCGGCTTTTGATGTGTTTGGATTGAAGTCTCTTAAGAATGGGGGAATAACGATAAA TTTATTTATAAA

TAATGTATCTTTATCAAATTTTTCAATAATATTTAGTTTACTATCACGTTGTAAACT TTCTGTTTTTTTGA

ATGATAATTTTTCAAAATTATTGTATAAGAAACTTACACCGGTTTCTCCGTTTACAT CATCCTCAACTA

GTTGACCATCTTTAATGGTAAAATATTTTAAACCACTAATACATTCTTCAATTCTTT TATCTAAAGATAT

GATTAATTTATATACTACTGGGTGAAATATTCTGGTATTTAAATCAATATATGCAAA CTGATTTGATCT

CGATTTAGACCCGATTTCTCCAAATATTTCATAACTAAACAATCCATCTTCAGTAGG ATAATTCGATTG

ATTAAAAAATATTGGGTTTGTTATTTTTGGTAAGTTATTTTGTTTTACTACATTATC GATATCTAACAAA

TTTATTTTCAAAGATAAACAACCACCTTTCTTTTTTAGGTATCACATTTTAAGATAT AATAAATATTTGT

TTAATAATAGTATAAGTATTTAATTAAATGCAAGGATCTTAGAAAAAAAAAAATAAG AGAATAATATG

TCATTATATTATTCTCTTATATACTGATTTGTCTAGTGAATCAATATTCTTTAATGA TATTATTATTTATA

AGATAACTTACAATAATATCGATATCAATGGCAAAATTTTCTTTATCATAAATATCT TTATTTAAAGAT

GTATATTCAATACATTTACTGATGATATCATCTTTACTGTATAATGATTTATCCTTA TTCATTACAATCC

AGATGATATCTACATTATTTGAAGTATTTTCAAAATTTCCATTATTATTCAAATCAA TTAACATTTTAAG

AATAATAACAATGTATTTAATAAATTCATTTACAATGTGACCATTAGTAATAATATC ATTATTATAATA

ATGTTGTTCGTATATTTCATAACTTTCATTAGATTCAATTTCATTAATAACAATCTT TCTAGGGTTTAGT

ACTTCTAGTGAAAATACATCCAATAAAAATTCTAGTCTTTTATTTAATACATGCCGA TTAATTCTTGAA

TTCTGTTGTTGATGATTCTGAAGATCAATATTATAATATTGTTTTATCAAGTTATAA ATAATATCTACAG

AGGTAGTATGAATTTTATTTCTTGAAAATTTTTCATTTTTTCGATATTTATATAGGT AACTTAAAACTTT

TGCATAACTGTCATCAACAACAGTCTTATTTTTACATACAATATCTTTTAATTCAGA TGAGCTAATTGTT

AACGATAACATATAATATACCCCTTTTCTTTATAGTTTTATTTTAATCAATACAAAA CACTTAGACATA

TCTAAATGGATATCATGAATATTATACTCAGATAAGGATTTTACAATATGATCTACA ATAATGTGCATT

TCATTATCACTTAAGTATTTTTTATTATTTTTTCTAGATAATAGATTAATCTTTAAT GTAAATAAATTTTT

ATAGAAATATTTTGAAGATTTAAATAATTCTGTATTAATTGATTCTTCTAAATATTG CACATAACTATT

ATTTAATAATTTTTTAGTATTAACTGTCATATATATTTGATCTTTATTAAAATTAAT TTTATTTTTAAAAT

CTTTAAGTTTCATAATCATAGAATAATAAATCCATCCATTCGTATTTTTATTTAATG AATAAAATACTC

AACTAACATAAGAGTTAGTTGAGTATATATCCTAGTTATTTAGTAAATATGCAGCTT GTAAAGTATCTT

TATCAAGACCATAATCCCTATTAAAGTCTCCATTATTAACACTAATTATTAAATTAG AAGGTTTTATCT

TTTCAAATTCTTTAACTTGTTCTTTTGAAAATAATGCAATAATATTTAATACGTCAC CATCATAGTCTCC

ACCTAATCCGGCAAGAACATTATTACATAGGCTTAGTGTTTTATCCGAAATATCCTT TTTAACTTTGGC AATATTCATTAATAAGATACTTGAAGTGGATATTGAAGGATTTCGATTTAGTATAATATA TAAACCACC

TTCAGTTTTATTAATCAATTCTTCCATATAACGATACATTTTTTTATTAAATGTATT TTTAGTATCTATAT

GGAATTTTTCAGCTTCCACTAAAGAAATATTCTCTGAAGTTGAAATAAGATTAATTA ATGGACCCTTAT

ATAATTCGTGAAAAGTAATATAATTCATATATACTTCATCCATTTTACATAATGGGT CTGGAGATATAA

CGTTTCTTGCAGAGTAGTTAATTCGAGTACCTAAAATCTGTTTACGAATTGTTCCTC TTTTACCTTTAAT

ATTATTTTTAATAATACTATCTACAATTTTTAACACGTCAATCTGTACTCGATACTG TAATTTTAACTTC

TGAATTTTAATATCTTCATAGATTTCTTCATCACTATTGACAATATCTTTTAACATA TTTGTATGATTGA

TTAAGAAATTGTAGTCATTATTTATTTCAGAAAGCCGAAATAGATTTTCTGAAGCAA TTAACTGAGCCG

GTCTCAATTTAGGACTAAATATTGGTAAGCAGTCAATAAACAATAATCCTTCAAAAT ACCAACGGATA

ATACGTTTATATTCTAATGAATTTTTCTGTTTTGTATCAACATACTTTTGGAGTAAT TCAATAAATCTTT

CTTTAAATTCATCCAAACCGATATTCCGATCCTCAAATTCTTCATGCTCACTACCTT CTTCATCTTCTAA

ATCAACAATATTTCCATTTGCATCAATACGCTTATTATACATAATCATATCAATAAA TTTAGTACCATC

AAATAATTTGATTAATCGATCAAACATAATAGGATTAACTACATAGTTATTCTTAAA ATCTACATAACC

GAAGTTATCAATATTATCCCTTTCAACTTCAGGACCATAGATTTCTTCAGAAAATAT TCCATCAATAGA

ATATTTCTTTTCTTTTTTTGTTACTGGTTCATGGTTAGTAATAATTTTATCTTGTTC AATTAATTCCCTAA

AATCGATAATCCGTACTCTAGTCAAAAGTAATCAAGCATCCTTTCTAACACCTTTTA GGCTTTTATCAT

ATTCACGATTAATCATTACATCCACATATGAATAATTCTTAGCTTCCGCTTCAGATA TCTCTTCTTCTGA

GAATCCTGAGTTGTAGATTGTTCTTTCTTCAACAATATTATCAATAATATCCTTTTT CTTTTTATTAAAT

TTTGTAATAATCTTCTGATAGAAGGAGGTTTTACTGATAAATGCAGAGATCACTGTA AAAACAATTATT

GTAATCATAATACATTCAAAAATAATAGTAAACATTTCCATCACCATTCTTTATTTA TTTTTTTATTAAT

CATCATAATCAGTTAAGAAACCTTCAATATCAGGTTTCTTTTCAAAGAAGAATGTTC CTGAATTATTTG

GATCATATTTCTTACAGAAAGGTACTACGGTAAAAGAACTTCCAGGGTCTCCTGAAC TAGTACTTACT

AAATCGATCTTTCCAACAAAGCTTGGATAAATACCCCTAGCGCTTACTGATAATCCA TTAGCTGTTGCA

GATTGTGGACCCTTTACAGAACCTTTTAGATAACGAGTAAATAGATCCATAGAATTA ACATTATTTGA

GAATCTTACTAATTCGCTGTTAGGAATATTATTTACTAAGTAATCTTCTTTAATATT GCTAAATAGTGTT

TTTAATTTACTTACATTATTATTTTTTGGTCCAACTAAGCGATATCCGCCTTTGGAT AATTTTTGAGTTA

GATCATAAAATAGATATTCATTAACCCTTAAACGTTTATTGGATAAAGAGTGATTAT CTACTTTTAAAA

TATTGTAATAGTTTGTAATCATATTTCTAACAATCGCATAAATATCTTCTTTATCTT CTGAACGTAATCT

TAAATTGGATCGAGTTGTATTATCTAGTAAACGTTCAAAGGAGGATAAGATAGATAT AGCTTTATCAA

AAGTCATTGAATTATTATTTGTAAATACCGAACCTAGTTTTCTCTTCCAATAATCAG AATCAAAAGATT

TTTCATAATCAATTCGATTATATTTAAATAGATCTACTAAGGTTGCAATTAATGTTG CATTAGATTTTTG

ATCGCTTTCAATCCATTCTCGATTAACTTTTAATGCAATACTTTTTGTCAACTGGAA GAAGTAATATTCT

GGACTAGTAATATCATGATCTTCAGTTTTAACGATTTCTACATAATTATGAATATTA AAGTATCTTAGA

GTTTCAACTACACCTTTTCCTGCAAAATAGTAGTTCATTACATTTACAGTTTTCTTA AATAATAGTGTCA

TTAACGCTCTAGTTTTTAATGGTTCACCATTATTAAAACGTTCATCAATATCAGATA GTACAACCTTTTT

ACCCTTAATCTTGATTGGCATAAACATTGTTTTCAATACAATAATTCCATCATTAGT ACGATAATACTC

GGAGTCATTCATTTGGAATACTGGGAAAAATTCATTTCCGTTAATTAAGAAGTATTG TTGATCTAATAA TTCAGGGAATAATAGTTTAATTTCTTTTTGGATTGTTTCTTTTCCATCAGAAAGTTCCAT TGTAACTTTA

ATTCTAATAAATCTAGATTCCTCGATATTAACGGTTGGATGGTTAATCTTTCTAGCT TTACCTTTTTTAT

TTTCTTTCTTTTCTTCAGTAACTTGTTTTCTTTCCTTATAGATTTTCCGATCTGTAT CAATTTCACATTTA

ACAAAACGAATACCTTCTACAAATTCAAGTCCTTTAAAAACATCTTCAACTAATTTT GGTAAGTTTTCT

TTAGATCTAAAGAAGATCACTTCCTCATTAAATGGAGCTTTTTCTTCCATTTTATTT TGAAGATCATTAA

AGAGTTTTCTTGACAAGTTTGGCACAAACAAACAACTCCAATCAAAATTTATTTTAT AAATTTTTATAT

CGTATAAAAACAATTAACTATTATTAGATAAAAATTTGTTTTTATATAAAAATAAAA ATTTAAGGATGT

GTATATACTATGTTGAGAAACGGTGAAGAATTTTTTAATGAATGGTCTGAAAGATCA GGAATACCTAA

ATATGAATTAAAACGTCAATGGAATATTATGGTAGAAATGGTTATGGATAGCATCAT GGAAGAAGATT

TTACCAAAACAGTATTACCAAGCATAGGCGCTTTTGAAACTATTGTTAAACCTCCAT ATATTGCTAGAG

ATCCTAGAAATGAAAAAGTTGTTATTGCACAAGTTAGGAAGCGAATTAATTTTAGAA TATATCGCAGA

TTTAAAAAAATAGTAACAGGATTGTTATAATTTTCGTAATACAGATATTTATTTCTG TATTACGAAAAT

_{CTTTTTAATTGTTATTTCTTTTAATAATCTGTTTTTCAATATAAATTCTATCTTC TTGAGATAGTCCATTA}

TATATTTCTTCTAAAGATTCAATATCTTCATTATCATTAATTAATACATCAATATAC CTATCTAAGATTT

CTTTAGGTACATTAGTTTTTAAATTATTGATATTATATGATAAATTGATCTTAGAAT TAGTAAATTTATT

ATCAACAATCTTTACACTTAACTGATTTCCATCATTACTAATATTGATGCTTGAATT AGTACTTTCACTT

GTAATATTAAGTTCAATACTTTTTAATATTTTGTTAATTATATTTAAATCCAAGTTA AAACATCCTTTCT

ATTCTTATATATTGTACATTTATATAATATATAAGAATAATATTAGTTGATGAATCG AGATTTAGCTTC

TTCGATAGTCATAATTTCTTTTTGCATTTCCTTAGCTTTAACAATTTTTGAAGAAGT GGATTCTTTATCT

TTACAAACTACAATATCAGTTTTTGAAGATACGCTACCTGTAACTTTATGACCGAGT AATTCTAATTTC

TGTTTAAATTCATTATCCCGAATTCCTGTAAAAACAATAACTTTAGATTCTTCAGAA GCATTATTAGAT

AATTCTTGTTTAATAGATTTTAGTTTAAATTCATTAATCAAGAATATCAATTCTTCT TCATTATTCGAGA

TACCGTTTAGTAATTTTTCTGCCTTAATATCTGAAAATCCTTCAATATTAATAATAT CTTCTTTCTTAGG

TAAAGATCCATTTACAAAGAATTCGTTAATTACTTCTTCCAAGATATATTCCTTACA GAATAGTTTAGA

GTTTTCAATACCTAATCCTTCAATACCTAATGAACCAAGAATTTGATAATCATATAG ATCACGTTTGTT

ATTAATTGCATTCTTGATATTATCTAGTGATTTTCTACCTAACCCTTCAATAAAGTT ATCATCAATACTA

TCATAATCTATACTATATAAGTCTGTGATTGAAGTCCATAATTTATTTTCATATAAT TTACTAATAGTAG

ATTTGTCAATACCTTTAATGGCTAGTTTATCAAGATAGTTAGATATCTTTCCAATAA CGTTTCCAGAAC

ATTCTGGATTATTACAGTATGCAAAGGTTTGATTATCATTAATAACTACACTTTCTT GCTGACATACGG

GACAATATTTGGTAAATTTGTCAGGAATAATATCTTTGTTATGATCACTATCTACTT TATCAATATATGT

TAGTGTATCATTCCTATATTGTACTAAAATTTCTGAACCAATACCTAAACCTAATTC TTCCGCTCTTGCA

AAATTATGGAGACTTTGTTTTGTATGCGTACTTCCATTTGAAAATGTAACTGGTTCA AAATGTACTAAT

TTAGTAATTCGTGAAAAAYYASSWAWKWSWTASCTAAARTCAGTAMTMCACAYTWTT YKWYTGYWS

WTARRSTASYYTAWSWRCARWMRAAWARTGTKRWGTACYKWTWKKAGYYATYMMTWR GGTGATT

TTTCACGAWWWTCGTCATCTAAAATTTCAACGACAATACCATCAATCATAAATCCAT AGTTATATCGA

TTATTAATAACTTCATTATAGAAATCATTAAATTCTTCAATGACTTTTTCTACTGAA TTACTTTCACTAG

TAATACTGAATTCTTAACCGATTAAACTATTTGATCCTAAGATATTAAAACTATTAT CTCGTTTAGATA ATGTAATTTCGAATGGATAATTATCTTCATCGAGGAATTTAATATCTAGAGGGACAAGAG TTAAGAAT

TTAGAGAATTTATGAGCATCGTCCCTACCTAATATTCCAGAGGTTGCGGATCGTGGA TTAACATAATTA

TTCTTTGTATAATCATTTAACTTTTCTAAATTATCATACGTAATAATAACTTCATTT CTAATTGCGAAAG

GTAGTTTGATATCATATTCTTGTAAAGGATCTTTAGCGATGCTCTTAAATACATTAG TGAGATCTAACC

CGATACCGTCTTTTCCACGAGTATACGCCTTATCAAACTTTCCATCTTTAAAAGTAG TAACTACTGAAT

TCCCATCAAACTTTAATGTAAATAGGAATGTCGGGAACTTAGAAAAAGGTTTAAGCT TATTAATCATT

CCTTGAATTACTTTTGGAAAATCATTAATATCTTTACATTTAAATAATGTTCCTGTC AGATTTTTATATT

CATGCTTCATATTAAGAATACCTTTATCCGTTTTCGGTAATGATCCTACAATTTCTT CACCAGTTAATTG

TAAGTATTGTTGATATAATTGGTCATATTCAAGATCAGACATAATTACTGTATCTGT ATTATAATACAT

GCTTGATGCATTTTCTAAATATTCTTTTACTAAATTATATTTATCATGTTCTTTACT GTCTAAAATTCTTT

TTGATTCTGTATAATCCACATTTTTCAATATCCACACTTCTTTCTATATTATTATTT AATATTAATCTTTT

TTCCATTAATGGTAATATAGTTATATTCACTGTTATAAGATACATTTATAATGTCCA TATCAGCATCAT

ATACTTCATCTATTTCTTTTTCATCAACATATATTTTTCCATTGTCTAATTTTATTT CATATAATCCATCA

CTTATAACTATAACATTATCTATCTTTTTATTATAAGTTTTAGATTTCTTACCATCA ATATATATTTCAC

CATCTTTTAATAACACATTTAAACCATTATTATATATATTGGCATTTCTATTTTGAG GAAGAGTTTTATG

TTGATGAAAAATATTATTATATACTTTTTTAATTTTATTTATCACATCATCACAACC TTATTTAATCTTA

AGATATATCCTATCACACTATAAAAATGTGATAGGATACTTTTTATTTATTTTTATA CTTATTAATATCA

AACTAGTCTTTATTATTGGTATATTCATTAAGCATGGATTCAATATCTTCATCACTT AATTTTTCGATAT

TATCAAAATCATTTTTATAATCTGGATCAGTATTAATTTCAACACCTATAGATTTAA AATATGAATTGA

TAATTTTATTATTATTACTAATAGTGTCTGATTTCTTAGGTAATTTAATGTCAAAAG GATTTCCGAGAA

GTTGAGCTTTTACTAAATTACTTCTATCTTCAGTATTATTTGAATAAGCATCAGTTA ATCTTTCAATAGG

TTCTAAAGATCCTACTAATCCTGAATTGGTATATTCCATTTCCAATTACCTTCACAT AGATTCGCAATTT

CTATGCAGTTCTCTTATGAACTTCTCTAAGTTTCCTTAGAAGTTGAGACTATATCTT TATCTTATTTAAA

ATTTCTTTTTGTTTTAAGATACTTCCCATTTCGCCTGTCATTTGCTTACAGACTACA TCAATAGTCGTTG

AACTTTCTTCCAATAATTGTTGGAAGCTTAGCTGCTGATTATCCATTATAATTGATA CTTAGGAATATT

ATATTTATACCAGAATATAATATCTTTTTATCTCACCATATATCATTCCAATTATTT TTTCTATCTTTCGA

TAACATTCACGCTTATCATTACTGATTGCGTTTTAGTTAATTGGACTTTAGGAGTTT CCAGCAATTAAA

GAAATTTTCATCATATATCACTATATAATGCGGCAAAATTTACCGACTCTAATTGGA GTATTATTAGTA

ACATTATCAGAATTTTTCATATCTTTAGTTTTTGTTGGAAGATTCTGGAAGTTAGTA TTACCTTCACTAC

GAATAGATGTTTTTTCAATAGGCTCATGTTTAAGTCTAAGCATATATAGTTGACCCA TTTCAATAGGCT

TACTAATTCCACTTAGTTTATAACGATCGATATTGAATTTATCACGAATATCTTTAA GTTTAAAAATAT

CCATATCATTCCAGAATGGTGTAAATTGAATATAAATTCCATTCTTTATAGTATCTT CTAGATAATGAT

CCTTATCGCTATCACTTAATTGATCATATATACTGATTAATGATTTATACATATTTT CATCAATAGACTT

AATATATTCAGATAATAAATTAAACTTTTCTTCACGACTATCCATATGTTCCATTCG ATATCGAATAAC

TTGAGACATCATATTGAATGTATGTTCAAATGATTGTGAAGGATTTAATCGGTTATT AACGCCAAAAG

GATTAAGAATAATATCCGCTCTATTTTCTAGGCAAGAATCTTTATCAAACTCCTCAC CATCAATAGTTT

CAATTACAGGCATTTCTTCGTCCGGAAGAATTAATCCAATAATTCCTTTATTACCAT ATCGACCAGTTA GTTTTGAACCTTTCACAAGAGGAATTCTTTCTAAGATTGTAAATACCGCTACAATACGGT CAAACACTC

TTCCCTCAGACTGAAATTTATTTGCAGGATCATTAAATGCTGCAATCTTATTATAAA ATGCAGATAAAT

CACTACTGATATTATTTCTTTTACTAGATACAATAGGTTTTAAATATTCTACAACTT CAGAGTAATATTT

TGAGATAGAAATATATTCATTGTACATCTGATGATTATATTTTTGAGATCGTAACTT ATCAAGACTTTC

GTTATTATAAATATCAATGTCAATAACAATACCTTCAGCATGTTTTACTGTGTCAGT AGCAAAGATCTT

TCTTAAATTGACATCTTTCATACTGAATCCCATATCATTATAATTAATTCGACGAAT TCCCATTAACTTA

CCATCTTTAATTTCTTCACCAATACTAGGAAAAGTTCTATATGATTCATCATCGCCA TATAGATTTAAT

AGTACATCATTGGTATTTAGATTGATCTTAACTTTCTTTATTAAATAGGAAGCCATC TTTTGAGCAGTA

CTCTCAGAAACAACAATAGAGTCTTCATTTGTGAATCCTTTGTATGGAATATATACC GCATTGAGATTT

TTACCATACTGAAAGTTCATATCTTCGTCATAATTTTGATCTCGATAAATTACTTTG TTTTCAAATTCTT

CATTTTCATTGATATTATCAATTACTTCATTATTGAATTTTAGTCCAAAGTGTTCTG TTAAATGTTTTGC

TTCTTTTCGTTCTACAATATGATAGAGTTCTTCTTCTTCATTAAATAATATTGCCGT GTAATTAAATTTA

TTCTTGTAAAATTTTTTAAGAAGTTTCCATCTACCATCAAGCTTTTTATATCCAGTA GAATATTTACCTA

CTTGATTTTCAAAACCAGTAAAAACTAATGGTGGATCAGCTTGTTCCAATTGAATAT TTTGACTTAAAT

GAGAAGTAAACATTTGTGACCTATTAGAGTTAGTCTTATCTAAGTTTGGAATGAGTA ATGTTTCGGCTA

AGAAATCAAATTTACCTTTATATTTTTCATCATTAATCTCTGTTAAATCCAAAGTAT AACCACACTTTCT

_{TTTTTTTTTTAATATACTAATCTATCCATTATATAAGAGTTATTATATTATACGC TTATTGGATAGATTA}

GTACTTGTAATTATTAAGATTTATTTATCATTTTCTTTTTCGATTTCAATTAAATTC ATGTCAGAGTCAT

AGTATCTTCCATCTGAACCAACCCAAATATCTTCATCTTTATTAACGCAGTCAATAA GAGTAACAATAT

TATCATTCTTGGTAGATTTTGGAATTGTTTTAAACACTTGATTTTCACCATAAGCGT CAAAAGCATTTCT

AAATTCTTCATTAGTATTATATAGTGTAACAAAATCTTTACGTTTAAATTTAACGTC TGGAAGAGTAGG

AATAGAGTATCCTCCTTGCGGTGAACCATCTAATAGTTTATTATCTTTAAGATAAGC AAACAGTGAAAT

ACCGTTAGAGAATCCATTAAGTTGATCAAAAACAGAATTAAATGAGTATCCTGAAGC CGAAATACGG

GACTTAACAATTAGTCCATCAACTTCTAAACCTTTATATCCAGTTTCCTCTTCCTTA ACATTTTTACCCG

GATTCAATTTAACAAATGTATTAGATAAATATCCAAAGGCAGAACCACCTGGAATAG CTTCATCAATC

TTTAGATGATTCAGCGAAGCTTTAGTCTTAACTACTGGATTAATTTCAATCTTAGTA GTAATATGATTA

ATCGCAAATAACATGATATTTGCTTTTTCTAATGCACTTGAGCCAATTAATCGTTTA ATCATCTGATTAT

TGTATTTTGCTTGTGCTGTTGCAGACATCTGTCCACTCATCTTTTCTTCTTCACTGA TGTCTTTAGTATAC

ATAGCAGCAATAGAATCTAAGATAATAATTGTCGGATCGAACTCATAAATTGGTTTA CCTGTAATTGG

ATCTAATTTACCTGTATCATGTTTAAGTTTATCGCCCCTGCTAAGTTTCTCTTTTTC AATAATTTTTACTA

AACCATAAAGAGTTTCTGTCGATATTCCTGAATTAAGAAGATTATACTTTTCAAGAA TCTTTTCATCAT

CCCACCCAGTAATATTTTTAATACGAGCTAATGATCCGGCATGCTCATAATCTAGAT GATAAATTTCAG

AATTTTCATAACGATCAACAATATTACATGCAATTTGTTGAATTAATGTTGATTTAC CAGACCCGGATT

TACCTACAATGGTAAATAATTTACCGGCATCTAATCCCATCATTAATTCTCCCTTAC TATCATAACTTG

CTAACTTTGCATCAATCTGACTGAAACCCGTTCTATAAGTTTCAGTAAAATTTTTGG ATTCACCTAATC

CATCTTTCAATAACTCTTTTTTAACTTCATCTGTAATTAATCCCATACATTTACTTC CTCCTTAGATATC

ATACATTATAAATCATTGTTATTACAATAAAATAATTTTTTATTTATAATAACATCA TACTACAACATT CCCTTCAGTATTTTTATTTTAACATATTTTTGACGTAAAGTGGAGATAATTTTTTACATC ATAATTTATT

ATAAAATGCTATAATGAAGATTATACTTCTTCATTATAGCATCATTAATTCTAATAC TTAGATAATATT

AATTTAACAACATCGTCAGTATTTATCATTTCAAATTTTGACATATTATCAATATAA TCACGTAGTTTAT

CAGTATCAATCAAATTACAATAATCATTTCTTTTTACAATGTCTGTAACTATTTGTC TAAATCTAGTGTC

TGATATGATTACATTTACATCTTTTATAAATGTATCAATGAAAATTTTTATTGTATT TTTTGCAATATTA

GCTTTATCAACATCAAATATTTTATCGATAATTTTATCAATCTTGAATGCATAAAAA AGTAACATTTCA

TAGTTCATATCAGGTAATTTATTTTTTGCATACATAATAAATACTTCGATAGGGTCT CGCTCAATTTCTT

CAGTTTTTAATAATAATTCATAAATATAGTCTCGGATAGATATTCGAGATAAAGCTT CTTGCATTTGAT

TAATAAAGACTGAAGTGTTATCTAATGATATTTTTTCTAATATTGTGATTAGTTCAC TTGCCTGTTCATC

AACTAATCTTTTATAAATAGTATTATCACGCATATTATCTTCCTGAATTATCTTAAA TTCATTTACAAAA

GTCAAAAATATTCCTCCTTTCTTCAATAGTAAATAATCACAAATATATAATATATAT TTATTATTGAAT

TTTAAGATCGTTTATATTTGAGATGTTTTCTTCTTTAACATCAGCAAAATCTAAATT AAATGTATCGGA

ATCATCTAGTAAATCATTATCAATTCCTGCACCAGTAAGAAATTGGGATACGGTATT TAACGTACGCTT

ATCATTAATGCTTCCCGGTAAATCTTGTAATGAAGTATATCCATACATTGCAATATT TTTATACATTGT

AGATTTTGCGTCTTGTGAGTCCGCTCTAGGGCTTAAGAATTCTTTTAATGCATATTT AGCGTCAATAGC

ACTTAATGCAATAGTTTCTAAGTCACTGATCCGTGCAATCTTATCTTCGTTTGTTAC TTGGTTGGTTCTT

AAACTACGTTTACTAATATCTAATGAGTAGGTATTCTTTTTCGATAAGGTTTGTTAT ACTGATAGGTAA

AGATATACTATAAACGTATTCTTTTTCCCCCAGTCCAAACCGTACGTGAGACTTTCA TCTCATACGGCT

TTCCATCAAATTTATTTCATTACTTAGAATAAATACTTAATAAATAACTATTCTAAT TAATGAAAATTA

GATTTGACTAAGAACTTTCTCTCCACTATTTATTATCATAGCTTCATCGATACTTCA TTCTCTCTTACTC

CCTATAAATAGGGTATCAAACGTTCCCTTTAAATTAGGTATATAAATGTACTTAGGA TCCACCTGTTAT

TTATAACAATACTTACATATAAGTATAATATGACAACCTATTAGTCATATTAGCTAA TAAAGACTACA

ATTTTATTTCGCCTATTATAAATCATTAAAGTGATTCGTATTCCTATCCATATACAT CTACCCTAACCGC

TATAAGTATTATTAGCGACTTCATCCAGCTTCACACATATTAATTACTCAATATGCA TGTGGAATATCA

TTAATAGCAATTCATGACTATTATTTAGGTTAGTCACAGCTTATTCATTTAAAGAGT TAATTATATACG

CATATATAATCATGCAATCCTCAATATTTTTACATATCTTTCTGCATAACGTTTCGC ACGTAGTCTCCTT

ACGGGAAGATAACCTAATGGTACTGGATATCTAGTTCTTAATGGATTATCTTTATTT CCATCATGACGA

TAATAGATATATTCTTCTAATGGTACATTCATAAAGTCTAGTGTTTCTTTAATATCT ATCAGTTTTGGTT

CATTTTTATTCGGTAATACTTCTAAATAGAAATTATCATCACCATTAGTAAATTTTT TCATATACGATAA

AAATTGTTCGTCACTCATTTTATCGTAAATATCTTTATACTTTTTAGCATTAGAACC AGTTTTATCTAAT

TTATTGAATACGTCAATAATATACTTTTGAATTTTATTTCTTTTTTGTTTATTATTA GATACTTCTTCATT

TAATTCTACCGATTCATTGAGATTATCTTTTGTATCCATATAATATACTGATAATAT TTTAAATAAATTA

ATCGAATTATCTTCAGAAATATCATACTTCTTAATGTTTTTATCTTTAAAAGGAAAC TTGTCAATACTG

AATTCAATAATCTTTAGACCATCTAGATCACGGTTATCGTACTTATCAGTATATAAC TTAGAAAGATAA

TTTGAACTAATTTCCCTAATTTGAGAAGTATTTGATAATCTAATAGATTCAGGATAA CCAAACTCAGGA

TAATAATTAAATAATACATAACTATCATTTTCTTTGTAATAAGGAAGACTAATATAA TCTATTAATTCT

TTATTTTTTTCATTATATAGACCCATTATCATAAGTTTTGTAAAAGGTTGAATGTTT CTTAGTATTAAGT AAATAATAGTATTAATAACATTACTATTCAACTTGTGATAATCAGTAAGAGTATCACTAT ACTTGATGA

TATTGAATAGACTCATTTTTATACTACTATTATAACTTCGATTATTATCATTAAGTA TAGATTCAATATA

CTTAATGATATCTTCTTTATTATTAATATCATTTCTAAATATAATATCCATTATATA ATCATTAAAATCA

_{ATTTTTGTAATATCAATAACCGAATCCTCATCAATAGATATTACTCTTTTATATA ATGATGATAATGGG}

TATCTTACAATACCAGAACGGGTATATTTAGTAATTGATAATAATGAGGGATGAGAT ATTAACTGATC

TAATTTTATAGATGGATATAATTTACTTTCTGAATCCCTGAGTTTAAATAATTCAAT ACCATAAGTTCTC

ATAATGGTCATAAATACGCTTACTAATTGAATTTCTCTTATAGTTGTTTTATTTCCT TCTGCACTTCTAA

TTATTAGATCATTATCCAAGTATTGATTATAATCTTTAATCTTATCAGAGAAAGTAT TAAACTGATCTA

TAATATTAATATTATTTTTATCATAATATATAGGAAACTCAATTACCTCTGTAAACA TATCAATATTCTT

TAACTTCTTTTCAAAATTGGATGTAAACTCAGATACTTCCATTTTTTCATCGTTATA ATCAATTCCAAAT

ATTCTAGAATTATCATGACTATCTATTAACGCAATTTTACTTAGTCTATCTTTAGCA GAACCTATTACCC

TATCAATAATTAATGTAACTTCTAATTTACATTTATCCTCTGAAGGACTATTATCAA AAGGTATATATT

CATTATTATCTAGCATTAATGCATTATCTGTAAATTTTCTTTCATTCCCTAGGTACT CATTATATTTTTTA

TTCATATAATTATCCAACTATAATTCACTTCCTTTATATTATTCACTGGTATATCTA TATGTTTATATTA

CTAGTTATTAAAATCTTTTATCAAAAAAAAAAAAAATATTAATTATTAAATACATAG TATATAACAATT

TATTTGTTATATACTATGTATCTTTTTTTCCTTACATTATATTGATTAGAAATTTAA ACCTAACCAGTAT

CTAGCAAACATAGATTTATATGAAACTAAATCTACAATAAATATTGATACGAAAATA ACCAATGATAA

AGCAATTACCCAAGATAAGAATACAATTACTTTCTTAGATAAATTAAGATTAAGTAA TCTTTCTTCAAA

TCTTTTTAGTGTAAAATTTTTCATGTTATCTTCTAAGAATAATAAGATTGTAATGCA TTTTAATAGTTCA

TTAAAGATTCCCACAATTTTGTTACTACCATTATTTTTATTTACTATTACTGTTTGT TTTTCCACTTTCTC

CACACTCCTAATATTATTATTTTCATTTTATAAATTAAAAAGTTAACCTATCATCAG GATAATAAAAAT

ATCCAATGATAGGTTAACTCGTTTTTCTCTATATTTAAATAATATTTAAACTATTAA AAATTATAATCA

ATCTCAGACTTTTGAAATTCAGCTTTCATTCGTTTTAGTTCTTCTTTATCAATATTT TTTTCTGACCTAAT

AGTAGTACCTGTTGGCACTTTTATATTAGTAATCATTTTGCCTTGAACTGTTAGGAT AATATTTAAAGT

AATCAATATAAGAGCCAAGAGCAATAATGAACCAATAATAAAAGATGAAATATATCT ATCTACTTTCT

TTACATCTTCTTTATGTTTACTCTGGTTGGATTTATATTTCGTACTAAGATTATCCA TTCTTATTTTCACT

TCCATTCATTTTATATTAGTAATATAATTTATCTATATTACATAATGATAATATATA AACAAAATATGG

GTTATTACGCTTTTATAAAAATTTATAGTTAATGTATAATAATATTATATATTTTGG ATCATAGAAAAA

TATATATGCTTTATAAGTATATATTATAAATTTGTAGTAAAATAATTAATTATGGAG GATTAATATGAA

AGAATCTTTAAAGTTTAATGTCAAGGAAGTAAGAATTCTTAGCAAAATCGCATCTAA TGAATATGCTA

ATGAGGAAAGTCGGTATGAAAGCTTTTTATCTAAATTGGAAACATTTAATAACTTTC GTTCAGGATTTT

TATATCTGTATCTAAAGAATCTTTCAGAAAGTGGATTAACTAAACAAGAATCTTTAA ATAAGGCTATT

GATAAATATGTCAAATAATTCAATAAGATTTAGAATAATGGCAGATATTTATTGTAA TAATAAATTTAT

CAATGTTGAAGAATTAGAGTTCACTGGAACGAACGAAAGTAACGCAAGGAAACAATT AACTGGTTAC

CTTAATAGACTAACAAGAGAAAATAATAATGGTAGATATACAGCTAAGAATATTAAT ATAATACCCAT

TAAATCCCAATTTCAAAACAATATTGAAAATCAAGAACAACTAAATCTTTTTAGTAA TGATATTAATG

ATGATTTATAATCTAAGTAAATCATCATTAATTATCTTTAATAAATTATGAAAGTAG TGATATTTTTTTG GCTAAATTAAAGAAAAGCAAAAGACGAGTATCCTTTGAAACAATTGTTAAAAGGGTTATT GAAAAAC

ATTTTCTTGAAAAGTATGATAAAGCAGAACTAGATTTAGATAACGAGGAAACGTATC AAATCGGGTTA

GGTTCTATTGATATTGATAAATACAATATCAATCCTGATGATTTCGAAACCTCTGGA ATTTATTATTAC

AGTAAAGGGAAAATATCTTTAGATAAAGATTCATCTCCTTTACGAACAATGAATGTT AATGTAGGAAC

TGTTAAGCCTTTATATGACGTAATATATGAAATTGAAATTATTTCAAGGGTAGAACC AGAAATTAATA

ATTTAACAGTATTAGGATATTTTATTAAAGAATAGATATGGATGGTGAAATAACATT GACAAGAACTT

ATTCTGGTGAAGATATTGATGTTTTAGAGGGTCTAGAGGCTATTCAGGTTAGACCGG ATATGTATGTA

GGAAGTTCAGATGAAACAGTCAATCATCTTGTTAAAGAAGCAATTGATAATGGTGTA GATGAATTTCT

TAATAATTTTGGAACAAAGGTTATTGTTGACTTAGATACTGAAGAAAATATTATTAC AGTTATTGATGA

TGGTCGAGGATTACCTACTGACATTCATCCTAAAAAGAAAATTCCAACAATGCAAGT ATTGTTATCAG

AAGTACATTCTGGTGCAAAATTCCGTAAAGATTCTTTTAAAGTTTCTAGTGGTAAGA ATGGCGTTGGTA

TTAAAGCTGTTAATGCATTGTCTGAATATCTCCGAGTAATTTCTATTAGGGAAGGAT ACCAATATTCAA

TGGAATTCTCTAATGGTAAAGTTACTAAAGAATTTAAGAAAGAAAAGCAAAAAGAAT ACAAAGATAT

CAAGCATGGAACAATTATTGCATTTAAGCCTAATGGAGAATTTATCGATAATTATGA CAAATTTGATC

CAGAATTCATTAAAGATAATTTAGAAAAGCGTGCATACAGTAATGCTAATCTTAAAT TAATCTATAAA

GAAAAAGGTAAAGAAGTAGCTACGTATCATCATGAGAATGGTATTCGAGACTATATC ACAATTCTTAA

TAATAATCCTTTTACTAGTAATCATTATTATAAAGAAGAATTAGAAAACGGCGACTT ATACGAAGTAA

CTTTTGGATATAGTAACTCTTCAGACGAAAATATCTATAGTTTTGTTAATGGATTGA AAACTGCTCGTG

GTACGCATGAAACCGGATTCAAAATGGCACTTACAAACTTAATGACTAATTATATTA AGAATAATAAA

ATGTTGCCAAAAAATATGCAAGCTAAGGCTATTACGGGTGAAGATATTCGTTCTGGA TTAGTATGCGT

TATTAATCTTAAGTTGCAAAAAACATCATACAGGTCACAAACTAAAGATGAATTATC AAACCCTGAAG

TTTCTGGTATTATTAAGCGGATTACAAATTCAGCAGTAAAAGATATTATGGATACAA ACCCTAGTGAA

TTTAAAAAGGTATGTAGTCGTATTATTGATTTTGCTAAAGGAAGAATTAATGCTTCT AAATATCGTGAA

AAGATTGTTAAAGATACGAATAATCTTACATTAAGTTCTAAATTTTCAGATTGCCTT TCTAAGGATCCT

TCTGAAAGAGAAATCTTTCTATGTGAAGGAGACTCTGCAAGCTCTGGAATTAAAGAA TTCAGAATCTC

TCAAACTCAGGCAGTATTCCCATTAAAAGGTAAACCTAAGAACTCTTATGGTCTTTC TAGTAAAAGTTT

ATTAGGTAATGATGAATTTAATAATATCATTAAGATTATTTTTGGTACTAATGATAT TAAAAATATTGA

TTATGATAAAGTCCGATATCATAAAATCATCTTTACTGCAGACTCAGATACTGATGG ATTACACATTAA

TTCATTATTAGGGTTATTCTTTTATACGCATTTTAAAGAATTATTTGATAGAGGATA TATTTATATCGCA

ATGCCACCTAAATATAGTACTTATGATAATGTTTCTAAGAAATTTATTTACTTTAAG AATGATAAAGAA

TTAAATACTTTTAAATTCAATAACATTAAGAAACGTATTAAGCTTAGTGATGATAGT GAATTTAAATTA

AAAGACTTTATTAATAATATGAGCGAATATCAAAATCAGTACAATATTGTTAAACAG AATAATAATAA

TATTTCCGATAGCGTTATTGATACATTCTTATTACATGGTCATGAAAGTAATTCCTT TATTGAAAAGAT

CCTTCTAGATAGGAATAACTACAGATTCAGTAAGAATAAAAACGGAAATATTATTGG AATGCACGATA

ATGCTTGGCATGATATTAATATTGACTTATTAAATAATGATATTAGTCGTATTAAGA AAGTTATGAGCA

TTAGCGACTTGTTTGAATTTACAGATACCAAAACAAATGAAATTTATAGTAATGTAA CATTAAAATTTC

TTATGGATTATATCAATAGTAAATTTACGTATAAACTTAACTATTTTAAGGGTCTTG GTGAAGCAAATC CTGAAGAATTGTTTGATACTACCATTGATCCTGAAAAACGTGATTTAATTCAGGTTAGGA TTGATCCTG

AAAATGAAGAATCAACCCAAGAAATTACAGATATATTCTTTAAAAATAATTCAACTC AAAGAAAAGA

ATATGTAAATAGTTGGTTTAATATTAAATAAAATTTTATACAATTCGGGTATTACTT AGAGTTAATCCC

GAATTGTATAATTAAATTAAAATAAAGGTGGTTCATACTTTTGGCTATTATTCAAAA ACAACTTGTAAA

TATTCATGAAGAAAATATGGAAGAATACTTTGTTGAAATACTTACTAGTCGTTCAAT TCCAGATATTAA

TGATTCATTAAAACCCAGTCAACGAAGAATTATTTATTCTATGAATAAAGATCGAAG ATTTAGTAATTT

ACCATTTACTAAATCTGCAATGATCGTAGGTTCTGCATTAATGATTCATGCCCATGG TGACGCATCATT

ATACAATACTGCAGTAAATTTAACTCGTAAATTTTCTAACATGCAACCATTAGTTGA AGGTCACGGATC

TTTTGGTAACGTATATGATCCTAGACCTGCTCAAATGAGATATACTCAAATGCGACT AAATAAGTTTAG

TGAAGAAGTTTTACTAGATAATATTAATGATAACTGCGTTGATTTCGTACCATCTTA TGATGAATCTGA

ATTAGAACCTGTCGTTCTCCCATCAAAAATTCCAATGATTCTTATCAATGGTTCTTT TGGTATTGGTGG

AGCATATCGTTCATTTATTCCCCCTCATAATCCAAAAAATGTTATTAATTATACAAT TGATTATATCAA

AAATCCAAATAAATCTGAAGAATCATTAATTAAAGATAATGAATTATATCCGAGTTT CCCTCTAGGTG

GTATTTTAGATAATAAAGATATTATTAAAAAATATACGACTGGTGAAGGAAAATTGG TTCTACGTGCA

AAGATTATTAAGGATGAAAATAAATCTACTCTTACCATTGTACAATTACCATACATG AAAACTCAAGA

TATCATTATTGAAAATATACAAGAAGCAGTTAAAAAAGAATACATTAAAGATATTAA AGGTATTGATA

ATGGTTCTGAGCGTGGTAAGATTAAACTTATTATTAAATGTTTTAAGGGAACAGACC TAAACGTAGTA

GAAAGTCAATTATATAAGCATACCGGATTGCAAAGTACGTTACCATTAAGCTTTGTA TTAGTAGATCA

AGGTGACTTTAAAAAATATAATGGAATTAAACATATTATTTCTGATTGGGTTGAATT TAGAAGAACAA

CTATTCGAAGAATTAAAACGAACCTTATTAGTAAACTTGAAAGAAGGATTCATATAT TAGAAGGATTA

CTAAAAGTATTAGATCCAAAAGTATTAACAAAACTTATTAAATTAATTCGTGAAGGA AATAGTCGTGA

TGGAATTAAACTAAGTATTCAAGATAAGTTTGATTTATCTGTAGAACAAGCTGAATA TATTGTTGAAAT

GAAGATCTATCGACTAAGTAATATTGGTATTAATGATACAAAAAATGAATTAGCTGA TAAAATGAGGG

AATTTGACGATCAATCCGAATTTATGAAAGATCCTAGTCGTATCGATAAATATATTA TTGATGAACTAC

AATCAATCAGTAAATCTAAAAATCTTCGTAATGACTTTGAAATAACTACTTATGATG ATAATATGAAT

GAATTGGATATAGAATCCCTGATTCCAGACGAAAATTATACGATTGTTGCTACAAAG GGAAACTATAT

CAAGAAATTCATTTCAGAAATGAAAGTACAAAAACGTGGCGGTAAAGGAATTAATAT CGGCAAACTT

AAAGATAATGATATTCCTTTAGGAATTATCTCTGCTAATAGTAAAGACAATATTTTA TTTATTACAGAT

AAAGGTAAGATTTATAACTATAAATGTTATAAATTACCAAACGCTTCTAGTATTAAG ACGCTAGGTAA

TAATATTTCTAATCTTATTAAAAAGGAAAAGTTAGTATCGATTTTTAGCTTTACTGA TGATCAATTAAA

TAATGATAAAAATTGCTTATTAGTAAGTACTATTGGTAATAATATTAAGTTAGTATC AATGACCGAACT

AAAAAGTATGAATGAATCTGGATTAATTTTATCTAAACTTAAAGATAATGATGAAGT AACAAGTGTTA

AATTAGTAGACATTACTGAATCTAGTAATGTAATTGGTATCACTTCTGAAGGTATGG TTATTCGTACAG

ACATCTCAAATATTCCAGTTATTAAAAGAACTACACAAGGTAGTAACCTATTTAATA ATAAATATATT

ACAGAAAGTAATAAACTTGTATCGGTATCTCTAGAAACAAAAAATACTACTGGTCTG TATATTATTAC

TAAATCAGGATTATCTAAACGTGTAAAGATTGATGAATTCAGTAAATATCCTAGAAG GGTAAAAGGTG

TAATGGGGATTAATCTAAAAGATACTGATGATAAAGTTGTATCTATGGAAACTTATG AAAATGTAGAT GACCATAATCTTATCATTATCTCAAATCAGAAAGCAATTTCCATACCTCTTAGTGATATT TCTGAGTAT

AAGAGACCTGCAAAAGGACTAACACTTCAGAAGCTTGAAGATGACAACTATATTATT GATTCATGCTT

AATTTAGTATTAGAGGGTAAGCCATTGTTTATTGATGGCTTATCTTTTTTTTTTTTC ATTTATATATAAA

AATTAACCTTTTATATAACAATATTATATACTATTGAAAGGTTGTGGAAAATAAATG GCAAAAGAACT

TATTTTAGATGTTTCTCATCATCAAGATCCCAATAACTTTAACTGGGCTAAACTTAA AGATGAAATCGA

TCTAATACTAATTCGTGTACAATATGGATCAAATACTATTGACCGTCAATACAAGAA ATTTGTTGAGCT

TGCTGAAAAACATAAAATTCCTTTTGGTCACTATGCTTATGGTGTATTTGTTAGTTC TAAAGATGCAGT

AGTTGAAGCTAATAACTTTTTAAAACGTGGTGATAGTGAAGCTACTGTATGGATTTT AGATGTAGAAT

CCGACACTATTGAGTCATGTAAAAATTCTCCTCTAGGTGAAGCTTCTCAAGCATTTA TCGATACTCTTA

GCAAAGCCGGAAAGAAAACTGGTTTTTACTATGAACATCTTATATTGGAAAATATGG TTTAGATAATG

TTAAAGCTGATTTCCGCTGGATGCCACGCTATGGAAAAAATGATGGTACTTTATCAG GAAGTGCTAAA

CCTGATATTTCTTGTGATTTATGGCAATATACTAGTACTGGTAAGCTAAAATCATAT TCCGGTAGTGCT

TTAGACTTAAGTATTCTTAATGGTAAGAAGGATATTAAATACTTTACAGGTAAAGCA TCATCAAATAA

ACCATCCACTGTTAAACCATCTAAGCCTTCTAAACCTAGTGATTCAAAAGATACTGT AAAAACTACTA

GTTATTATGTTACTGCAACTAAACTTAATATTCGTCAAAAACCTGATGCTGATAGTA AATCTTTAGGAA

CATTGGATCATAATGATCGTGTTCAAGTTATTTCAATTAGTAAAGGTTGGGCAAAAT TAAAATCCGGT

AGTAAAGAAGTATATGTTTCTGAAAAATATATTTCTAAAAAAGCAAAATCAAATAAA CCGAAACCAGT

AACCACTAAGACTTATACAGTCGTAAAAGGGGATACTCTTTCTGGTATTGGCAAAAA ACTTGGAAAAG

ATTGGAAAGCATTAGCTTCTAAAAATAATATTAAAGGTCCAGCTTACGTAATTAAAC CAGGACAAAAA

ATTAAATATTAAATATTTTATTCACCATACAAACAGATCATTATATTTAGTGATCAC ATATGTTTGTAT

GGTGATCTTTTTAAGAAAGAGGGTTTGAAAAGTTGACTAAACAATCAATATTATTAA ATAGTTTTGAA

GAAAAAATTGAACAGGCATTTAAAAATAGTAGTAATGTAAATAAATTAGTAAAAATT GTAAGTCAAT

ATATTGATAAAAATAGTGATATATTAAATCATAATACACCTACATATCGACTAGTGT TTGCTCGTGAAG

GATATGATGCTGAAGTTATATATGATATAGTTAATATATATCCTGAAGAAATTAAAG AAGTTATTTCAC

AACTAACATTTATTCGAAAAGAATGGAAAGTAACCAATGAACCCTTTTCGGTATTAA TGACTTTAATT

ATTCGATATTTTCATTTAAAAAATAATCGTAGAGCATTGCAATCTGCAATAATGTAT CTTTCATTATCA

TTTTATTCATCGTTACATTTTAGATCATTTAGATATGAACCGAACGATAATATTATG CAGTATACAATT

AACCGTGTAAGTAATAAATTCTACTTTAAACAGTACGGTACAGTATTTAAAGCACTT AATGCTACTGCT

GACAAAGCAGATATGAATCTTAAAAACTCTTTAAAAAAGAATGATGACGAATTAATT ATTGCATATAT

GACATCCCTAAGAAGTCGTCTTGCAAACCAATTAACTACTTTTGCCCAAGAGTTTTA TAAAGACCATGC

AGCTAATAATTATTTAAATAAGGTATCGGATGTTTATGATGACGAAAACCATATTGA AAATACAAATG

TTTCTGGAATTGTGATGTCACAAACTAGTAAAGTATCTCTTAACTTTTATCAATCTA GACTTAATGAAA

AATATATTATGATATCTGCATCTACTTCTAAAGTTACGGCTAATGCAGTAAGAAATA CATTAGAAGAT

GTTAAGGAACATGAACGAGAAAAAGTGGAAACGATTATTCGTAATACAATATCAATA TATTTAAATGA

TCGAAAAAATTCGGTAAACTCAATCGGATCACAGAAATTTATCAATTATTGTATTGG AATATATACAA

AAAGTAATACAAAAGAAAAATTGGTATTAGAAATAAAATCAATATTAAACTATTTCT TAAAAGAATAC

TGTGATAAATATAACAGTACTGATAGGGAAGCTACTAAGAATAATTATCGTAAAGCT GTATTTCTTTA CTTTATATTCTTAATCAGTGCAAATAACTAAAAAAAAAAAATATTAAAGAATATATCCAT ATAACCAA

TAATAGGTTATATGGATATATTTTTATTGCTTATTTAAATTTCTTCAGTATCCCTTT TTATTAATTCATTT

ACTTTTTCTGATATAAATATAGTGGATATTCCCATTGAAATCATTGTAATCAGCATA AGTGTTAATAAC

GCTAAAATTAAAATTTGCATAATAATCATTATAACCATCCTTTTAAATTTTATTTTT CAATTACAGTACT

TGTAATATTACCATCAGTATCGACTCCAGTCATTACAGTGTATGTATTAACTACAGC ACCATCTGCAAA

TACGCCATCAGTTCCTTTAGATTTTACAAATACAATGTATGTATGTTCCCCATGAGG ACCCATTTGTTC

ATTGTCTTCTGTAATATCATAATATAAATTACTAGTATTAATATTTCCATATTTTTT AGATACAATTGAA

GCTAGATCTTCATTAGATAATGTTGTTGACATATATACTTGTTGATAATTATTTAGA TCAACTTTTTTAC

TATTTTTTACTTGTTCTTTCATTTCGCTTAATTTACTTTGTTTATAATCTACTTTAT CAATAGATAATGTT

TTTGATTTAGTGTTATATTTAACCGTTTTATCTTTAATATTGAAAATAAGATTTCCA TTTTTATCATCTTT

AGATTGATATTTGTCAAATTTATCATTCAATACTACATTATCATCTACATGACCGAT TTCAACGCTAGT

ATAACTACCTAATACTAAATGATCTTTAGTTAATTTTACATATCCTTGAGTATCTTC ATTATAATATTCC

CCAGTAACTGTATTGATATCTGGAGTCTTTTCTTTTTTAATTGTTACTTTCTTTTCT TTTTTCTTATTTTCT

TTAGAAGGAGTTTTAGTTTCAATTTTCTTAACGTCATTATCTTTCTTTACAAAAGTA TAATTGGTTGACA

CAATCCCAACAAATATTCCAAGGGCAATAGCTACAGTAATAATTCCAGTTAGTATTA ATTTCTTTTTCA

TGTTGATCCATCCTTTTCTTTTTTTTTTTATTTAAATGTCTAATACCGAATAGCTAA TCGATATTAGACA

TAATTGAAAATTTATTATTTTTATTAATTTTTTTATTAATTAAATTTTGAATTTTAA TAACTTCTTTTTTA

AATTCTAAGTTTCTATCATCTATACCTTGGATAACTTTATCAAATTGATTATATCCA ATAATATTTACAT

ATCCTTCTAGACCAGAACCTTTTATATCCTTATAACTGGATATAATAAATGATTTTG CATTACTTTTTAC

ATATAAATTTGAATTATATGAATTATTAGTTTTTCTAATTTTAATATATGATGATAC CATTTTCTTAACT

TGTTTTTCATTCACAAATAATACTTTATATTTATCATTGATATATACTTCTTCAGGA ATAATTCTTCTTTC

TAACATGTATGGAACACTTTTATTAAATGTAATTTCTGATGTATCATTATTATAAAT AATATTATCATCT

TTACGAATATTAATATATTTATCAATATCTTTTACAGTATGAACTGCAGATAACTTA TCGAAATTAATA

TCAAATTTTTCCATATAAATATAAATATCTAGTTCACCGCTAATATATTTACCGTTA TCATATGTGATTA

TAGATACGGTAGTTTTCGTAGTTCCATTAAATTCAGATGTTTCGATATTATGCGTAT TAAGAATTATAT

ACTTAAGATTATTATTATATAATTTTTTGATCTGTAAAAATAAGTCATTTACACTAT ACATTAGCATAA

TAGTTAATACCAACTTCCATTATTAATTTTTAATACTAGGATAATATCTATTAATTT AGATATTATCCTA

GTGATATTTTATTAATCTTCAAATACAACGAATCCGTAGATATTAATTGGATCTTCT ACTTCAGTAATT

ACACTAAATGTATTTCCATTAGCACCACCATTATCTTCTACTACATAACCACTGTGA CCCATCACTTCA

GTAATATTATTATCCTGTAGTTCTTTCATCTTACCATCATCAAAAAAGTCAGGATCA ATTTCATCCACC

CCTAATGTATAACTTTCTGAAATGACTACATCTACACCATACACTTTTTTAATTTTT TCCGTTAATTTAC

TTACGTCTAATGACATAATAAACACTTCCTTATTATTTATTTTATTTCATGATTATA ATATATATTTGTA

AATGTCTTTATTACGGATTAATCGATATTCTTTTCCTTCAATAGTATTTATATTTAA TGACATAGGATTA

ATATGTGGATGTAATACTACACGTTTATAACTGAATACCTGATTCATAAGTTCAATA ATATTGTCAGCA

TCAAAATTATCGTTTATATATTCAATACTGTATATAATATTTTTATGCATTGAAACA TTTAAACCAACA

TCAATATTATTCTTATCTAAATATTCTTTGATTAGATTAAGTCTATTTACGATATCA TATTGGTCTGGAA

AACAGTTCATTAAATGGCTTGCCCTTCCTTGAATATTTTCTTCAATTATCATAATTT CTTTTATTTGTTCT ATTATATTATCCAACTAATTCACTACCTTCTTTTAATATATTTGATAATTCTTTATAATA TTTTCCTTCCA

ATGTAGTAATAATATTATCATCATTGTCTAGAAATATTAATGAGAATATCTGGCAAC TATTTCTTGCAA

TAAATAATTTATTAACTTTTTCACCTTTTTCTAAGAATGTATTAAGTTTAATATCAT AATACTTATAATA

AAGACTTCGCATAATCCAACCAATATCACGTTCTTCTTGAATATATAATGTATCATC ATAATCTGGAAT

AATATCTAATTCATATATTTTTTCTGAATCATCATAATTGTATGAACTAAACTTATG TTCACTATTAATT

AAGGTATGTGGTCTATCAAAATAACATTTATCCTCTAGTATTGTACGATTAATATCA TTACGTAAATAT

CCTAAGAATATCTTTTTATAATGAGTATTATTAGTAATCCAATCCGAAATAATACTA AAATCATTATTA

TTTAATAACTGGTTTGATTCAATATTATCCATTATTAAACAAATATCTATAGTTTTT GTTTCTTGATTGA

ATATTCCAATTTCCCATACAAAACTAAACCAGATCTTTTTACCCATATATCCAGTCA ATATTCCTGCAA

GAGGATTCTCTAGAGATATTTTTACTAAAGGTGCAGCCAATCCATTAGGAGTGAAAC AACATTTTGTTT

TAACGCCAATATTCATTATTTCATCAACATCTTTAGAAAAGTAAATAAATTTATTAC TATGATTATTGG

ATATATTCATTTTAGATTCAGATACATTATATTTTGTACCTGCACGAGCCAATAATA CATTATTGATAT

ATTTATTCATTTCCTTATAATTTAGGTCAGATTTTCGAATTACTTCATAATTCATAA AAGGTAATAATTT

AATAAACTTATCATTATTATATTTAGATAATGAACTTTGAAGAAAATTATATGCTTC ATCAATATAATT

ACTATTTACTTTTTTATTTGTAATATATTTATTAGTAACTTTATTAGGAAATTCACT AACAAATCGATGA

ATGGATATATTATTGACTACGCATTTATTTAAAATATTCATTAACTGTTCATATGAA AATAAATTAAAC

ATACGATATAAACCATTTTTCTTTTTATATTTAACAAATTGTATGTCAAATAATTCA GGTTCTAATTTAT

TATCAAGATTATTATTGTACCAGTCCTTAATAAGCTTTATCATCTTATACATTCTTT TTTTACCAAACTT

ATCATGCAAAAACAGTATTTCATGTTCTAATTTAAAATCAGTAATTGAAGCACCAAT ACCAATATTTAA

TTGATGTAATTTTTCAATTATTTTAATTTCATTATAGATTTCACTGTCAATTTGAGA AAGTGAAAGTACA

TCTTTATATAAGGATGCAATATATTCTTCATATAGTACATTATTATTCTTCAATTTT TTCATCACCACGC

TTTATAGATTCAAATATATTAATATACTTATCATATAATTTTCTAAATTTTCCAGTT TCATCAATATGCA

AATAGTATGACATCTTACCAAGTAATTCATAATCATCATAATAACAAGATCCGGTTT TCATATATGAAT

ATAAGTTATTACGCATATCATCATACTTTTCTGAACTTAATGTTAATTGATTTTTAT GATTTATCGTAAT

CCCAGTAATATTACGCATATTCCCTTTAAGATAGACAGTTTTACTATCATTAATTTT AAATTTATCATTA

TATATCTTGAATGCCTGATTACATATCTTAATGATAAATTTTTTATTAAATAGTTTA TTATTGTCAATAT

TTGTTGAAAAAGTAATATCATCCGAATATGAAGAACAAATTATTCCATATTTATGGA ATATGGTTTGTA

TATGATTAATAATATCTACCATAATAATATTCGATATTACGCCAGAAACTGGATTAC CTAGAAACATTT

TATCATTTTCATCAACAAAACCTTTCTTTATAGTATCCATATATTTATCAGTAACGC CATGGAATAATA

GTAATATGAATCTACTATTAATTAATTTCCAATCAATACTAGGAAAATAATTAGATA TATCTACTTTAA

TAATATATTTATTATTAAGGTGCATTAATGCATTATCTTTTATAGATACATTTTTTC GATAAGCCATAAT

ATTTGGATATTTCAAGTTTGATATTTTTCTATCTAATCTTTTATCGAGGATCTTAGA AATTTCTTTTAAT

GTATTTTTAATTTTTATATTTGGATCAATAACTTCACGTTCTTTACCATTTTTTTCT ATCTTGATTTTCTT

AAATAATTCAATATTATTGTCCTCTAAGTCTTTAATGATACAATATAACTGAATTAT TTCTAGAGACAT

TCTTCTTTTTAATAATAATTTTATATCACTGGCATATTTACTTTTAAGTTTATAAAT TAGATATTTACTAT

TACTAATTTTAGAGTTGGGATATAATAATATATATCCTTTACTTACTGATACAAGAG GTGTAGATGAAA

AAGATCTATACATACTAAAGAATTCACTATATTCCCTCAGCTCAATAGAATTCTCTA ATAAATATTTTT TACTATAGTTAAAATCTATACTGTTGGATGTCTTATAATAATTCATAATCTTAATTAATA AGTCATAAC

TATCCTTAAATAGTATATTATTTAGCTGAACTAACTTTTTTTCTGAATTATCAAATC TTGATATTATTTT

AATATCTTTATCATATGGATAAAAGATCCCTTTATTAGTTAAAATTCTTAATGGATT CTTACTAATTATT

AATAAATCATTCAATATTTATCTTCACCTTTCTTTTTATTGTTTTCAAAAAAATTTA AAATGACCGAACA

TTCTTTATACTAATAATGTATAAAGAATGTTCGGCTAGTATATTTTAGATAGATGTA TACTTTTACTACT

CAAATATAATAATACAAATTATGTTAGTACGAATATACAGTATACCGCACGCGCTGA GTGCGGTATAC

TAACACGCAACCGAAATCTATGAGGTGCGTGTTAGTATAATTAATATTACAGAGAAT AGTGTTAAGTG

TTTGAATGCATATTAACGATACGTTAATGCTTATCAAATATTAAATGATATATTGAG AAAAACTAATAT

TATATTGATAGCTTAATATACATCTATTAAAACCAAAATTATATTATATTATTTACA TAAAATAATAAT

TTTTTATTATATATAAAATCAAAAAACAGGAATTTATTGACCGGGGTCCGAATAATG TCGATTTATCGC

ATGAATGGACCCGAAGCAATAAATTGCATGTATAATGGAAATAATTTTTTGACTAGT GACGATTACAT

CACATATTAATCATTTTATATATAATATATTAACTTATAAATTGTAAAATCCAAGAA ATTTATGAAACC

GCAGCTCACGTCCCGAGTAATTTATAACTCAGAAATGTGAGCTGCTGGTTTTACTAA ATGATAATGAT

AGAGACTTTTTTGATTAGTGAAGATTACATCACATATTAATCATTTTACAATTTATA ATTACGTAAATT

AAATAATATTTTGATTTACTGATTATTAATCAGTCTAAAATATTCCTTCAATATAAT GATATATACTTA

AAATTTAAGTAAACTTTAAAAGCATATATTTGAGAAGGATACTTATAATTAATAGTA AATTGTAGAAT

CTAAACAAAAGAATTCAGCACTTCATTCGTACCTGACGTAACTAGTAAGGCAGGTAC GGAAAGGATGT

GGAATTACTTTAATAATGATAGAAACTTTTTTGATTAGTGACGATTACATCACATAT TAATCATTCTAC

AATATACAATAAATATTAAAATTTAAGTAAGATTTAAAATCAGTGAAAAGATTTGTG AGATGTCGGAT

CGGATCGAGAAATACTTGTATGAAGCGATCAGATACTCTGATATCAAACAATCAATA AAATACGACAT

ATATTGATTAGTGACGATTACATCACATATTAATCATTTTATATCTACTTAAATTTA TAAATTAATAAT

AATTTTTGCATCTTCTTTAATATTAACACTTTCCGGTCTAGAAGTTTTTAGAGAAGT TCTATCATTAAAT

CGAGTATCTTTAATAAATTCTAATCCATCAATATTAATTCTTTTCATAAACTGTTTA GAATTTTCATTAA

ATGATGATGAAATATATTTAATGTCATTATCAATAATAAATTTCTTTAGATCTTCAA AAATATACTTAA

TACTTGAGGTAATTTTTTTATTAAATGGAATTACAATGTCTTCAATATACAATAATT TACTATGGGTAT

CCGTATTAAAGCTTCTATTGTTAAATTGAACGCTCTCATTTTCCGGATCATAACCAT AAATATTAGATA

TTAAATATCCATAAATATCATTGTTATCATTACGAATAATATATGATGGAGACTTCA TTTTCCTAGCAA

TTTTCTTTAATTCAGAAATATCGCTATCTTGTTTCCAAACATTCTTTTCAACGTATA ACATTCTATTGAA

CCAACCCGGTGATGCCTTTTCAATAATAACTTCACTATATGGAGAATATTTTTTAAT AATATCTTTATTA

TCAGAACCAATATATTTAATATTATTTTTACGATCTAATACCGTAAATACATATCTT GAGTCGTCAAAT

GATGAATATCTATTGAAGTTATTTTCATAACAAATTAGCCCTTCACTAGAAGATCTT AATCTCTGAGTA

TATGAAACTTTATAATTACTATTAATATCATTACGTAAATATCCTAAATATATTTTA TTGTAGTCTGAAT

TAATATCAAGCCAGTTAATAATATATTCATATTCATTCATGTCTAAACTTTTTGACG ATTCAATATTATC

TAGAATTAAATTGGTTTCATATGATTTAGTATCTTCATTATATTCAACAATCTCCCA TACAAAACTAAA

CCACGTTTTAGTATCAAAAACGCCCTCAAGAATCCCTGCGATTGGACTTTCAATAGC GGGTTTTAATAA

TGATTTTGCAGCACCGTCTGGTCTGAAACAACATAATGTACGGAAACCAATTGAATT AATGTCTACTTT

TTCTTTAGTAAATTTAATCATATCATTATATTTACTATCGTCAAATAGCATTTCACC ATTAGAAGTTTCC CCATAGGATAATCCTTTTTTTGCGTTATCAATAATATTAACATACTTTCTTAGATCACTA ATATTTTTAG

ATTCCCTAACACCTTGATAATTAATATAGTTTAATAGCTTAAGAAAGTCTTTACTTT TATAAATTCTTTT

AATATATGCTAATATCGTATCAATATATGTTTCATCATCATCCAGTCTTTCTATTGC AGTCTTTGGAAAA

TTCTCGATAAAGTTATGAAGATCTATTTTATTTTCAGAATTACCCTTATTATATGCA TATGAGACAAAA

TTAAGAAGTTTAGTTGCATTATCATATGAGATTCGAATTAATAATGAATTTAATTTA CTTCCATAATTA

CTATTTTTTTCTTTAAGATTTGATATAGTAAAGTTACTAGTATACTTATCCTTAAAC ATTTTTGGATTAA

TACCTAAATGTGACTCAGATATAAGATCTGTAATTTGGTAAACATCCTTTAATTGTT TAACAGGTTCTA

CTAGATTGATATTACTTCTTAAATCATTATTTAATTTATTTGTTATTTCTAAATCCA TATTAAATTCATA

CTTATTAATGCGATCACTGAGAATACTATCTTCGCATGATAACATTAGCTTCATAAT ATTGATTGCTTTT

TTCTGACTGTTATATAATGCGGATAGATATATTAATGCACTAGTAAGTCTTTCACTA TTGATTAATAAA

AATTCTGGAGGAATAACTCTAAATCTTCCAATGTCATGTAAAGAAGTAATATTATTT ATTACCTGTAAT

AGATCAGAATTATCCATTGTATAGTTAAATTTAGAACAATAGTCTAGAAAATTAGAG AATATTTCATTT

AATTCGTTTAGATAATTTTTCATCATCTATATTATTGTAGTTGTCATATAAATACAT ATTATGATTCACT

TCCTTATTTATTAATCAACTTTAGGTTCATTAATTAATTTTAATTTAATTAACGTAT TTTGATATTCATTT

ACGAGATTTTCCATTTTATTAGTATTATCGATATAACGATAATAACTAATTCTACCT TTAAGTTCATTAA

ATGTCATTGAAATATTATTAATATTATTTTTATTCTTAGATAATTTAAAGAAAATAG TCTTTAGTAGTCT

ATACATTTTCCTATCTAATGTACATTGATCATTGTGATTAATTCGAATCCCTGTAAT TCTTCTTTTGTTA

TTCGACATTTTAATAGTTTTTTCATCTTTAATAGATAAATTACTATAATTATATACT TCAAATGCCTTAT

TAAGAATGAACTTCAAATATTTTCTATTAAAGAATTCACTTTTCTCGTTTGATGAAA AAGTAATATCAT

CTGCATAAATAGAGAATGTAATACCACTATCAATTAATACATTTTTAAGATATTTTG CCACATTACTCA

TTAACAAGTTTGATAATGATCCAGAAGCAGGATTCCCCTGATATAATCCACCAGTCT CTGGATTAATA

AAGATTTCTTTGAATAACGTATCCATTACTGAATCTTTATTATTCTTCTTCTTAAAA TTTTCTTTACCTA

ACACTAATAATTTAAAGTACTTACTAATATCTTCATATCTACAATTATCAAAGAATG AAGCAATATCCA

TTTTAATAATATATTTATTATTTTTATGAACTAATGCGTTATCTAGTATACCTTTTT TCTTTTGATAAGCA

AATAAATGTTTTTCAACACCTTTATTAGATAATTGAGTTTCTAACATTCCATTAAAG ATATTATTAAATT

TTCTACTAATATCTTTAATATCATTATGTGGAGCATAGATATCTCTAATTTTTGTAC CTTGATTAATCTT

GAAATGTTGATATAATTTTTCATTATTATTCTGAATTAATATTCTGGTTAATAGTAA CTCTAGTAATAAT

GGTTTATTATTTGGTTGATCTGGCGATATACTTATATCTAATAAATATTTAATCATT TTAATCATTTCTT

TATCATCTGTGATTTTATAAATATTATATTTATTGTATATATCATTTGTATTTGTAA TAATATAGAGATA

ACCATCATTCATTTCAATATATCTATGAGATATATTGAGATTTCTATAGGATAATTT TATACTGATATTA

TTAATAAACTCTGTAATTAAAGTTTTATCATAAGTAACAACTGGTAAATCGGGATAT CCTTCATTAATA

CAAATTTCATCATTTGAGAGCAGATCATAAGTCTTAATAATTTTTTCTATATTTTCT AGATGAATGTCAT

TAAATTCCTCGTTATTTTCAAATTTATTATTTTCTTCTAGATATGATATATCTTTTA TTGATTGAATCAAT

TTATTACGGATATTATATTTAACTAATTTAGCTAATACCTTTTTATCAGAAATAATA TTCTTTTTCATTC

GAATATCTATTTCTGATACAATCTCTCCATTTATATCGATTAATACATTATCGATTA ATATTAGTGATAG

CAAATACTGTCACACCTTTCCTTTAATTATTAAATTATTACTACATAAATTTACTAT TTAATATTCATTA

TATGATCCCACCTATTTATTTTATTTTACATTTTAATAATATATAAATAAAATTTAA ATAAATATTCCCG ATATCTCTATAATAGGAGATATCGGGAATATATTTTATTTAGTTACAGTTACGTTAATTT TTCTTTTCAT

GGAAGTAAAAGATTCAGGAACAACGGTAATAATTGTTTCACCTTCACTTACGCCAAT AAGTTTAGATG

GATTATTCTCATCCACTTTAACGAGTTCTTCACCTTTTTCTAGAATTATCAGAACCT TATCACTAACGAG

ATTATCAGGAGTCATAGTTCCGATAATATCTTTACTTTCGCCTTCTTTTATAGTAAG ATCTTCATCTACG

CTAAAACTTTCTGGTTTGGTAATTCTATCGTTAATTACAGATATTACGTCTATAGTA TCAATAGGTGTA

TACCACGAAGAAACTTGTCCTGCAATACCTCTTGATTCATCTACTACTTCATCATAA ATGATACAACCG

CTTACATCATCATACGTAAGTCGATGTCCAAAAGCTCTTGATGGAAAAATTTGAGAT TGGGATGTTGTT

ACAATTGTGGAGATTAATAGTGGATCAGATAAATCATTATGACGATCGATAAATCCT TTTACAGTTTCA

ATAGCTATCATTTTTATTATTCATTCCTCTCTATTTTAACGAATATTTTTTCTGCGA TTAAATTCAGCTTC

CTCTTTCTTTTCATTAAGGATTGTTAGATGAGTATCTATTCTATCTTGCTTTGCTTC CTTATCACTTTTAA

AAGTATTATTGTTAATAATACTTTCACTAAATACGTTTGGATGAGATATATTGCTTT TTTCATTAAATCC

ATCATTGAAGAAAATACTTTCATCAATATTTTTATTATCCATATTTATAAACATCCT TTCCTACATGATT

ATAAACCTTCAAAGAACTTCCACATATTCTCATCAACTTCTCCAGTAATAACCATAT TAGATACCATTT

GTATTTTTCTTACATTATTATAAGTATCCTTATCATATATTCCTGAAACACTAGTTG TTGTAATTGCAAA

TTTACGTTTATTATCATTTATCTTTGTTTGAATAAATAATACGTCTGGTCCTTCCAT AAGAGGATTACTA

TATTTAAGAACTCTTGTAAATTCAACAATAAGCGTATCAATAATATTTTTCCATGTT ATGGGTCCAACA

ATTCCATCTTCAGTAAGATTATTTGAATGTTGAAATGATTTAACAATAGTTTCAGTA GAACTATCATAA

GAACCAGTAACCTCAATATCATATCTTAGTTTTGAAAGTTTATTTTGAAGCGTAATA ATATCGTCACCT

ATCATCATTGGTGATTTATAACTAAGCATTCGATGATAGTTTGAATAGTCTTTAATA TCATTTAATGCA

ATTATCAATTCATTAATTTTATCAAAGTCTTCTTTCTTCATTCTACCATCAACTTCT AGATTAAATGTTTT

TTGGAATATTCTTACCGAGTTATATGTGTATAAATCATAGATACCATTACGAATAGT GATTGGGATATT

AATCATAGATAAATATATTTGTAATAATTTAACGTCATTACCGATAACTGGTTTTTC TGGATCATAGTA

GAATTCCCTTTTACCAAAACTATAAGAAACAGTTCCTGCAGGATTGTCTACATACAT CGGTAGAATAA

TAGAAAGAATTTGGGAACGAAGAACATTCATATCAACTAATGATCCTAGATTACTAT ATTTTGCATAA

TATTCATTTAATGAATGAATGTTTCTAATATTTCGATATCGACCACTAATATTAGCA CATAGATTCTCT

AGAGATACATATTGGCTTTGAGTTAGGTCTTTAATCTCCGTATTTCCTTCAAGACAT ATAAAGATTTTA

CTAGAAGATACTGGATCAGTATTATCAATGAGTTCAATATCTTTTCCAGCAATATTT TCATTAAGATAC

ATTTTCCGCATTAGTAAGTCAATATTACAAGGTAATGCTCTTTCGGGTCTACCTGAA ATAATATCCCCT

TTTTTAGTAATATAATAATGGAATGCAAACATCTTTAATCCTAACCCTTTATGAATT GATTCTAATGTA

TCATAATCCATACTAATATTATGACAATCTAAAATAACTATATTTGATGGATTATTC TTGTATATAAGA

TCTTTTACCGGGTCAGGAGTTGTATCTACATAGTTCTCATCAGTATTAGCATCCAGT AAAGATAACATG

TATGATATATGACTTCCCCACATATTATTCCATTGTTTTCCATCTACTGAAAAAGTT CCCGCTAAATCAT

TTTGATCATAAGAACCGCTTCTTGTAAATTTATTTAAGTATCTTAAACAACGGTTTA ATAATGAATACG

TAGTAGATATTTCAATAGTGTCATTTATGATATTTAAATAACGGATACACGACTCTG CAAGAATGCTTG

CATAATAGGTATTATCTCTAGCACTGTTTGGTTCATATACACTATTAAATTTTGTGA TTATCCCTTTATT

TTCAGAGTTCCATATAGTATTAATAGATTTTATAAATTTCATAATGATATTATTTAC ATTATTATTTACG

TAACCTTTTTCAAGAAGTCTAATTAATGAATTAATGATATTATATTGAAACTCTCCC CAATCTCCTCTTT GATCTAAACCTTCCCACCTAAAACTATTAGATGAAATATCAAAGATAGGTTTAAAGAAAC CTTCTACA

CCTTTTTCATTATAATATTCTTTTTGAGATCGATCTAAAATATCAATAAGTTTAGTT AATTCATTAATCA

TTCCAAGGTCATATAATACTTCTGGTTTTTGATAACCTAGATATATGTCATCGTTCC AACTATCAAGCTT

ATTATTAATAGTTGTTATTGAGTTAGGTAGCATTATATTTTTCATATTATTAGAATA ATTATCAACGCTT

TCGATATAATCGATATTTATAATACTAGGAATATCTTTTTCCTTTTCAATATAAAAC TTATTAAATGTAC

GATCTAATGAATAATTTAATAATGATCCGATATATTGAAGCTCAATGAAAGAAGAAG TAACCTTACTT

TTAAATATTGCTTTGGTTAATGGAAATTTAACAGATTTTCCATCAGTATTAAAATTA ACTTTAATACTA

TTAAATAAATCAACTGATTTAGGAAGATTTAATTTCCATTCTACATTATTACTATCA TAGATATATAAA

TCAATTCCATCACTAGCACGATAGCGAATTGTAGGGTTTGTTTTTGTATTTCGACTA AAAGGAATAACC

ATGTTTGACCAACCATCATAAGAACCATTATCATTACTTTCTTCATTAATCGTAAAG GTAGCTTTAATA

CTATTCCGAGTTTCATCATCAGTAGATTTCACTTCAATAATTTCAGAAATACTATTC GGAGAACTCTCT

GCAATATATAATGATTCTTCAGGAAGATTAAAATTATCCCAGATTACTTCACGGTAA TCTTTTAACATT

TCAGGAGTCAATCAATATTTATTAAATTCATTATCTTTTACATTCGTCTTATAGAAT CCAATATTATGAT

CTTTATCTTCAATAATAAATTTTAATACTTTATCATTATCGGTTTTAATTCTAGATT CTATATATGAAAT

ATCTTTAAGCGTAAATAATTTATTTACGCCAAAATGAATATCTTGATTAATTGAGAT TGAATTTAGTAT

AACATTTCCATTAGTATCATCACGATAAATTAATACAGAATCTGAACTATCTTTATT AATAAAAGAGCC

ACTATCAGATAATGGATCCAAATTATTTATTTCAGAAGTGATCCATCTAGGTTTAAT TGGCATATCTAA

TATAAATTTAATAGTATCTTTTGTAATATCCCTTGCCCTCATCCATTTACTATTCGG TAAAATATCATAA

AGATTACTATAACATTCATAAGAAAGCAATAAACTTTCAATACTGCATATATTTTTA TTAGGATCCAGA

GTATGCCAATAATTTGTAGGATCATATTTCTGATTAGATTTAATAAAGTTATCATTA TCTAATTGAGTA

TATACTAGTAATAGCGTGCTGTTAACATCTTTATCTTCTAATACAATCCTTACAGTA TTATCTTTACGGA

TATAATACTCTTCAATATCATAGCTTATACCTATAATATTAGAAGCCGGATTATTTT CATCACTTAATTT

AGAACCAAAATCTCTAACACTAAATAATTTTTTAAAATTGCTATCCGTACTAAAAAT TGCAATACCATT

AACAAATTCTGCCGATTCATTCAATATTAATTTTTCAGAATTAAAGGGTTCCGATGC ATTATATGTAAA

ATGAGGAACCCATAAATTATCTTGAGAAAAACTAGTTGGAACATCATTTGGATATAA GGTATCAATGG

TTGCATTCATCGTAGATTCTATTAATTCTAAGGATATACTTACGCCAGAATTATACT GATATATAAGTG

AATTAATATATTGAAACTGCGAAGTAGATGTTCCTGAATTAATATTAATATAATCAA ATAAGTAATCTT

CTTTTATATAATTTAATCTAGACATTGAATTAAGATTTATAGATAATGGACTAGTGT TTTTTGTATTTGC

ACTTACAAATTTATTATATTCAGATATCCATTTTCTAATATCTTTTAAATGAACATC TAATTTCTTTTCA

GAAAGATATTTTGTCAAATTTATCACCGCCATTCATATTATAACATTTTGTTTAATA TCAATTTAACTTT

TTACCCAACCTTTAGTATTATTATATTTATATTTAACTGTAGTAATTTTAGTTTCAT TAATAACTTTCTTA

AGACCTAATCTTAATACAAGTGAATCCCTATTAATAATATTCCGTGCAGAAACATAT CTAACTTGTTTT

GTAATGAATGGAATTGTTCGTTGAACTGTAGAGAATGGACTACTTGAGTTGTCTCTA CTCTTTGGTAAT

CTTTGAAGATTATCAGAGTTAAGCGTAGATATTCGATTAAGACCAGTAGGATCGATC TTCCATTTTTTA

CTTTTACCACCAAGATTAACTTTTTGTCGCCACGTTGCAGATCCTCCACCATACTTA ACGCTCGGGTTA

GGTGAAAATCCATTAGACGATGTAGTAAATGTAGTTTTAGACGCAAATCCTGAAGGA CTTTCATATAA

TGGCATTAGTAAATTAGATGGACTTCTAATGTATCCAATAGTATTTGCAGGACTGCT TGTTGTTCCAGT TAATGGCAATCCTTCAAACATATCCCATGATAAATATCTATTCGATATTCTAGTTCCAGT AGTTTTATTT

ACTTTATTATAGAATCCTCGATAAAATACACCAGTACCTTCAGTAACACTATATTTT TCAAGAGTTAGA

GGATCAATTGCCGAACCTTGATAGAACCAATCAGAAAATCTAGATCTTAATCCAACA CAAGCATCTAC

ATATTGGCTTTCTGAAGTATAATTCGAACTAGAGTAGTTAAATAATCTTCGATCCCA ACGACAATCATA

TGCAGTTTTTTCATATGATACACTTTTTTGTAATTGCATTGTTCCTGAAAAACTTCC CATTTTAATTAAT

TTCTGATTTACTTCATCCATAAGTGTTTTAATATTATTCCATATCTGTAATAATTCA GTATTCTTACTATT

CGCATCATTACTAAATGCTTCAGTCAATGAATTATTACTAAGGTTATTGAATATATC AATCTGACTTTG

TATTAAGTCATTATATTGTCCTAAGTCTAGTCCGTCTAATTGTAATGATATATCACC TAATTGGTTTACA

TTATTCTTACTTATTTTACCTAGATATACTGTTTTGAGTCGGGCAGACTCCATATCA GAAAAAATATCT

AAACTTGTATCAAATATTTCTTCTTGTTTATTATATATTTCATTATATATATTATAT AAATTATTAATCTT

TCCAGGTATTACATTCTTTCTTAATTTTATACCTTCCATATCATTCTCTAGGAAATC AATAATATTTTCT

CTAAGAACTTTAGTAATTGGTATTGGTAAGTTAATACCTTCCTCTGTAACGTATATG TCATGTTCTACT

AGATCAACTAATAACTCTCCAGTCTTCAGAGTATTAAAATATTTTTGAAGATAGTCT TGATACGACATT

GGTATATAAATATATCTTGACATTAAAATTACACCACCATTATTATATAATATGTTT AAATGTTATTGA

TTTAACCTTTTTATTACTTATCTTCCCTTTAGTCTTATTTACTAATGAAGTTACCCA TGAATCATATGTTG

ATTGAAATGCACTAGAATCTACATTTTTCTCAACAGTAGTATATCTTGATCTCATAT TAGTTAAATCAG

TTCCAGTTTTAGTCTTATAACCTTTTATAAAGTTGTATAGATATGTTAATTCAGATA ATCTTCTTTGTAT

TGAAAATATTCCAGGAAGCTTTTCTACTACTTTTGGAATAATTGTTGCGATAATATC TACAAAACTCCA

TATATCTACGGTATTTTGTCTGATTTGATTTTCCAATGTATTTAATATTGCAATGAT CTGAGCTAATAAT

TCTTTAAGACCGTTCATTCGATTATATAAATCATTTGTTTCAGATAATTTTGTCTGA TAGAGTGCTTCCA

AATTAGATATCTCTGTTTCTAATAGAGTAATAATGCTCTTAAGAGTAGAGACTAGGT ACTTCTGTGAAA

ATAACTCACCTTCAATATCCTTTGTAGCTGATTGATCATTAACAATTAAATGACCAG TACGAGTATTTA

CTAAAAGTTCTGAATCTTTCGATTCCAGTTTAGTTTTTTCAGTTAATGGCTGAACGT ACAATCTATATGT

CATAACTTATTATCACTTCCATATCATTTTTAAATTTAAGTTAGCAGTTGATATATT AATTATACCAACT

GCTAACTATATTAGAAACTTGTAATAATATTTACAAGCTTAGTATAGAATCCTTCAT GTTTATCTTTGA

ATGCATTATATTTAGTTGTTAATATCTTTTTATTAGCTTCGATTTCAACGCTTCGTA GATTGTAATAGTT

TCTACCAAGATTATCAATTACTGTAGTATATAGATCGGCATAATCTAATAAATCATT TCTTAATTTAGT

AATATTAGTACTTAGATTCATTAGCTTATTATAGTTTGTTAAGAAAGACCCATCTAC ATTATTTGTAAT

ACTTGTTATCTTATTACGAATATCAGTAATATCGGAAGTAGTTTTATCAACTTCAGC TTTTAATGCATC

AACCTGAGTTTTTAAATTATTTATTCCACCAACAACTGCATCTACAAAAGGTTTTAA TAGATCATTATT

ACTGTCAATTTCAGATAAATTATCTCTTAACCAAGATAATTGATTTTTATATAGATT TGTTACTTTAAAT

ATATCATATATAACTGTTGAGTTTAATGATAATAAGTTATTTAATTCTTTTGTAATT TCAATAATTTCAT

AACTACCAGTATCAGAATTTTTCGTATTAGATACAACGGATATATTTCCAGTATGTT CATCAATAATCA

GTTCTCCAGGAAATCTAAATAGATCATTTTCTCGACTAAACGGAATTAATACATTTC GATCAAGATCTA

CTGGAAGATTATAATTCTCAGTAACATTATTATCATGATCAATAATTCCGCTAGAGT AATTATTTACAT

CAATATAATAATAAGAACTATTATACATATTATTTGACTGTTTTCTAGCGGTAATGA TTAGTCGATATA

TACCATTTACACTACTGATATTCTTTAATAATGGGTCACCTATATTGATGATTGAAT TATTAAGTGAAG CAGTATATACAACTCCCGGTTCTTTATTAATAATATCCAATACAAAAGTTGAATCAATAT TAATAATTT

TTCCATGACTAATATTCTTAGCAATTGGTTTTGAAGGAGGTATGGTATCAATAGTGA TAGTTTTAGATG

AAGATGAACTTTTACCATTTAACTTACTAGTAGCTTTTACATTTAATGTAAATTTTC TAATAGATTTAAC

GTAATTATAGTTCTTAATAGGATCACCTAGAGTATACTGGTAAACCATTTATTGTAA TTTCATAGGTAC

ACATTGGGATTCTTACAATATTAGGAATGATCAAACTATTTGTAAGGTTTCCTGAAT TATCTGGAATAT

TAATTACTGGTAAATCTGGTACTGTAACATTTAACATGTCTGACGTAATTTCTAAAT TATTTTCAAGAA

TCATATCATTATCCATTATTTTTCTAGCAGTGATGATGCAGGGTTCAGTAATTATAA ATGGACCAGTAT

ACTCTTTCCAAGAATTGTTAATAGAAGTCTTATACAGTTTACTTTTAATGTGTTCTC TTTCAGACTCAAT

AAATACATATTCAATAGAAATATTATATGACTCGGAATAATATTTTTTATCATTATA ATCTATTCTTGG

TGGAGTATAAATATAATTCTTAACAATATTAAATTTAAATGTAGTATAACTTAACGT ATAATTATGTCT

ATCTGTAAATACTGCTAAGAATTCATGAGTCCCTCCCGAAGTGAATGTTGAACCAGA AGTATAATTGT

TTCCATCAATATAACAATTAAGCGTATAATTTGAATTATTATTCATTACAGTGATTG TTATATCATCAG

CACACTGAGATATATCTGCAGAACTCACATCAAAAGGAGTTAATGGTTTAGATGATG ATATTGATATT

GACGGATTAACTGGAACTGTAGTTTGATCCATTCCAGTAGTATTAATAGTCTGAGTT GCCATTAATTTA

TGTGAAGAATCAGAAACATTAGTGATATTACTTCCAGAAACTCAGCTAATCGTAACA TCATCATGTAA

ATGGTTTCTAGTTGATGTAGCATATCTGTATAATTTAATAGTAGAATCAAAAAATAT CGGCATATTATA

GTTAGGCATAATAAATTTTTTCTTACCATTATAATCCATAACATACATACTATTATC TTTATCAATTTTA

CTATCAGGCTTAAGAACAATATCATTAAATAATGGATTAGTATCACTAGATACTGAA TCATGATATAT

AACAGTACTAATAATATCTCCAACTTGTTCTGGTATAATAACTACGTTTACGGAAAT CTGTACTACATC

TGAATCTACACCATTGCTAACATTAATATCTAGATTATAATCTCCTTCATCTTTAAA TGATAATTTTAGT

TTTGGATCATTCGTATTAGTGTCTAATGGTGTAGCGGTATATGTTTTTGAAGGATCA TCAGTATCTGTA

ACACTATAGGTATACGATGAATCTTTTTCAATATGAATTATAATATCAATTGATCCA TCCCCATTAGTA

ATACTATCTACTATAGGTAAGATTAATGTTGCATTATCATCAGCAATAACTGAGAAA ATTAAATCTTCA

GGGGGATTAATCGTATTTATAAAATTAACAATCATTAATTCGTCTGAATTGAATAGT TTATTTATATCG

_{ATTTTTCGATAAATATTAATCTCAGTATCAGTCTCATATAGCCCTAGATATGTGA GCATTGTATCTGAA}

ACGTAATCGTTAACCTCTATAACGTCACCATCATCATTAGTTACCGTTATATTAGTA GATTCCTGTAAG

TCATTTACTAATTCATTCACATATACTTTAAACGTATACTGATCGGTACCTTTAGTT AGTTTAATATATA

CGTCATTATCTTCTGCAATTGTTATTGAAGTTGGTAATGATATACTAAACATGTTAT AATTATTTGAGTC

TATTGTAATGTCATTATCAGTACCATTAATATTTAGTTTACCATTATAAATTCCAGT ACCTTCAACGTGA

TATACTCCAGTAATATTAGAATCGCCAATATTAAATGTATCAATAGATAATTGTATA TTTTCACTTCTA

ACTACTAGTACTTTCTGATTATCTGCAACTAATATACCCTTTGAGTTGTATATCTTA AATGATATCTCAT

CCGTATCTGAAGATATTCCTGTACTAGATGTTATTTTCATCATTTTATCATTTTTCG TATTACTAAATTT

AGTAACAGTTGATGTAGTTTCAACACCATTAATATACATAATAATATTATCTAATTC ACCCTTATACTT

AGCAATAATCTCAGTTGGATTATTTCCATTAAAGAAGAAAGGATAAAAGTCTACTGC AGTATAATCAA

TATTTATTGCAACCTTATCATTAAATGTATCTACACTGTCTGGATCATCTGAGTCTT TTGGTATAGATGG

TTCATATGTGTCACTATATTTTACAATAGGATCTATAAAGTTGGTATATAATCCTGC AATTGAATCATT

CTTGACAATAGGTATATTTTCATTTCTGATTGATGTGTATGTTGATGGAATATCTAC TCTATAAACATC AATATTAGTACCATACGCAGAAGTATGTCTAATCGAGTCTGAATTGTAAAGATATTTATT AATATTCGA

TTTATCGATATATCCACTGAAAACATATATATCTGAAAATTCATCCATATTGAGAGT ATATTCCGTTAC

CGTATCACTAATAAAATCTTCATCTTCTGATATTGATTGAAATGATTCAATTAAGCT TTCTTGAAGATC

ATTAATAAAATCTTCGTTAGATAGATCATCGTCATCGCCAATAGTTGAAGCACTTAA CATAGTGATATT

ATTCTTACCAATAGAACCTTTTACAACTGAACCATTACCTCCTCCAATAATCTGCGA TATATTATTATTT

ACATTAAATGATAAATTACTTACATCTTTTGGTAATCTAATTGCTTTATATAGGAAA TTATCATTTATTC

CTTGAGTTAGTATAAATAGTTGATATAATATACTAGAATCATCAGAATAATCAGAAG TTCCTCCAAAA

TCATTTTCAATAATAACCCTAAATTTCAGTTGAGTTAATCCATTATATGCATTTGTA CTATTATTAAAAT

CTTCGTCTCCAGTAATAAATCTTACTCTACTACCGTTACCGCCTGTGGGTGCTGTAC TTTGTAATGTAA

AGACTTTATTGGTAGTACTCCAATTACTCCATTGATCCGATCTTTCATCTTTAACCG AATATTCTAGATA

TACTTTGTTAGCCCCAAATGATGGAATTGAACTTATAAAATCTTTATAATACTTTCC ATAATTACTAAA

GTATGTTATATCTGCAGGTCTAGAATATAATGGATTAATACCGTTATCAATAAAGAA AGGATTTACATT

ATCTATCTTAATTGGATTTGGTTTAATCCCTTTCATATCATAATTCATTTTAAAATA AAATTTACGTGGA

TCAACTAATGATTTATTAGTTAAATCGTTAAACGCTTCTATTGTTAATTCAAATACT TTATTATGATAAT

TATTATATACTGCGTTTGGATTATCGCTTGCCAATGACAAAGTATATCCTGACGTAT TCTCTTTATAAA

ACTTCTTAAGATCTGGATTATTAAGTGCTTTTATATTATATCGATAAATTACTGGTC GACCAGTTGAAT

CATTTACCCCTGAAAAACTAAAGGTATAATTAAGCTTATTTGCTTCACTAGTGTTTG CAGGAATCACTG

TAGGATTATTTGGATCATTACTCATAAATGTTAAAAATGATCGATCTTCATTTAACA TACTAGCAGTAG

TAACTATCCCCAGTGCGCTCTTACTAATATTTATTACGTTTGGCATATTAGAAAGAT TATTAAACACTT

CAGTATTATCCGGATCAATATTATCACTATATGATAGTACTGTATTAATTTTAGTTT CATCTGAAAAAT

AAAATGGATCAATATCAAGATAATATAAATCTCCAACTTTAGTATCATAGTTATCTT TAGATAATCTAA

ATTCGTGTAAACTACTCTGCGTTGTTACTTGGAAAATAATATCAACAAAAGCAGAAT CTTCCGTACCAT

TAATATTTTTATTTTCTAATTTTCCAAAAATAGAGAAACCGTTCTGATCTCCAACTA TAGACTCATTTCC

TTCCGTACCGGACTCAACTTCTATATTTGTGTATGTTAATGCTTCTCCATATGGATT CTCTACAAAGAAT

GTTCTAGCAATTCCATAATCTGCAGGAGTCCAACTTTGTATGAATTGTATTAATTGT TCTCTAGTATGT

GCTATTACTGTCAAGAAATTTCACCACCTATATTTATAACTTCTTATAATTAATAGT TTAAAAATCCAT

ACTAAGAAATATTTAATTCCTTAGTATGGACGATATTTTTATATTATCGGATCAATA ATATCCGCTTCA

GGATCATAGATTTTTTGAGGATTCATATCCAAAATAATATTCTGACTAATATATTTG TTATTTATTTCTT

CAGAATCTAATGAAATATCCCAACTTAATAGATCATTATTATTACAATTAATAATAG TTTTTCCACGTT

GACGCATATAGTCCATTAGAATTAATTTCCGGATACTACCTCTAGAATTATCATTTG TTATTCCAGTCA

ATATATCAAAATTACTAGTTTGTCTTACGTTATAGTATGAATGATAGTAATTATCGT TTAAATTCATTTT

ATCATACTTATACCAATCTAATATTAATTTAAGTTGAGTATGATCATCGTAGCTAAA TCTAATCATTAC

ATTTATTAATGGATCAGCATAATCAATAATTTGAATACTTTTACCATTAAGTATTTT TACTTTACTAGAA

TCTATTCTTAAATTATTAACGTAAACTGTAAATGTGCCTTTAATAAATATTACTGAA TCGTCATCTAAA

CTGAATACATCTGTTGTTCCTTCAGCCGGCTTACTAAAAGTTCTTATATAGTTGGAG TTTTCATTAAGA

AGATTTATTTCGATAGTAGATGTTTTAGGTACAATGCTTTTAAAAACAATTAATGAC GGAATAGATTCA

AAGTCAGGATCAATAATGGTATAATCAATTCCAGGATATAATGTTAATCCATCGATA TTAATATCGAT ATCTTCAGGATTACTATTAATGTTTGTAAAAATATTTGAATCATCATCTAACGTAGCAAA TGGTAAACA

ATCAATATCATATTCATTTAAGTCTAATTGATTGTAGTATAACGAGCCACTATTTGT ACCACTAGTCAA

AAGATGTATTTCGGTACCTTCATCCATATAAGATGAACCATATACGATAAGTCTTAC TGTATTATATTC

AGGTTCAATCTTAATATAATAATTGTATGGGTTAATTCTTCTAAAGAAATTCCAAGT TTTCTTCTTAATA

AAGACTCTTAATTGTGAAGGAGTAATTCCCGTTGGTAATGCAACATCCGTTAATAGT ATACCAGTAGTT

CCTAACATATTAGTTTGATCTTCAAACGTATTATCAATTATATGAGTCTTAATTGTT TTCTCGGATTCAA

CAATCTTACGTTTATTACCAGAGACAATTACTTCATATTTATCCTGAAGACTAGAAT TCCCATCTAAAA

CATCATTAGCATCATTCACATCAATATATTCTTTAATAAATCTTGAAGGCATGTATG CATATATTTTTCC

ATCTAAACTATCTTGTTGCTTAATCGATTTACGGAAAATATGTTTACCATTAATAAA TATATCAGATAT

TAATGAATTTTGTTTCTTTTCATATGAACCATATTCCGAAGTAAAATCAATATAACC ATACTGAGATTC

ATCATTAATAAAATTATTTATAAACGGATCTTTTGTAACTTTTATTTTAGAGTTATC CAACTTAGTTTCA

AATGAATTATGTCCCATTGTCTCTATAAATAATGTTTTATTACCTTGTTCTAATTCA TTAACTAATGATT

TTTCAATCATCCGAATATCATTGTCTGTATTCTTATATAAGATATCAGTAACATTTC TTGGATCAATATC

CATTTGGAATGTTTTAGTCTCTATAAGTTGTTCTGAATTAGTATTAAATATACTAAA GGTTATATCTTTA

TTGGGGGTGAAATTAAGTTCATCAATCTGTAATCGATAGTACTTTTCTTCTAATTCT GGAAGATCGTCT

GGTTTATAATATACACGTTGATAATTATCATTACCAATGATATTAATTAAGTAGCTT GAAACATCATCA

TTACTCTCAGAAGAAGAGAATATCATATTTTTAATCTTTACAGTAAGCTTATAATAA TCTTCGATTCTTT

TAAAATTATTAATGATGATAGTCTTTCCATCAATAGTTATTGTCATTATATATTCGG ATGATAATAAAT

ATCTTAGTCTAAAATAGATTGATCCGTTCAGATAGTATGCATTCTTATATAGAATTT TATATATAATGT

CTTCTGGAGTGGCTTGAATATTTTTATTAGAATATCTAACATCTAAATCTTCATTAA GAACAGTATATC

TAATCATATCATTTCCTAAAGGTAGCATTAATTCTGATAATACTGTTTCTTTATCAT CAAAAGGAATAT

ACATATTGGCACTTTGGTTTGCTTCAGGAAATATCCTACTAATAGAGTTCGATCTAT AGTTTAGAGAAA

CATTATAGTTACTTTTATCTACAATATCTAAACTATGCATTAAATTAACATGAACAT TTAAGAAAAATT

TACTATTTGTACTATTATTAAAACTGCGTTTTTCTATCCATGTATAATCAATACTTA AATCAGGAAGAT

ATTCTAATTTATAGAATGTGGTATCTCTACTAGAATTATTAACAATAACAAATAGAT TGGTTGCTACAA

TATTTTCTGGATAGTTATCTAACTGAATATTTTCAATAATATTTCGCTTAGTATTAA TTAATACTAATTG

ATTCATACTATCCATAAGAATAATATAATTTTTAACCAGTACTACTTTATCAATATT ATTTCTAACGTTT

GCTAACCATGTTTTATTCGTCAAGTTATTATTAGCATACTTAAAACTATATATATTT CCACTATATGATG

ATACGTATAATGTAGATTTATCACTATCATATATCATAAAATTATTTGTCGATAATA TTTTATCATTATA

ATCTGTCTGACTTAATGATACTTTTTCTACAATAGAGTTATCTACAGACTTAATAAT ATTAATATTAAA

ACTATCTTTTAATTCTAGTCCTATAAATATTGTAAAGTCGATATTATTCGATTCAGG AATGATTTCAAA

ACCAGAAATAAAATATGAAGCGGTATACAACACTTTTGTTGTATTCGTTATAGTATT TACTAGTATAAT

ATGTTGATACGTGGAGTAGTATATAAAATCATTAACAATCCTTAATTGATTTACTAA TTCATACTCATA

TGGAGAAGTATTAGTTATTTTATTTATAGTTCCTGAGATATTATACATTCCAGTAGT TGTATTTCTACTA

AAAGATACATAACTGATACCATTCTTATGAAACATATATATCTTATTATCGATAACT GTAAAATCGATT

ACTTCCTCATTAATATCAAATGAACCTACTTTTTCTCCAGTACCAAAGTCTTTTATA ATATCAATTCGAT

TCTTAATAGAACCGGTAGGATATTTATATAATCTGAATAGTTCTTCTAAATATATAC ACATTGCAGGCA TATATCCTGAATTAGCATATGATATAGAATGAAATAAGTCTAACCTATTACGTTTTTGAT ATTTATCTA

ATATATTCCCATTCAATGTTATAGTCAATACTTTCACCATCTTTCTTTTACAATTAT AAGGAATCGAGA

ATAAAATATCCCGATTCCCAATTTATTTAAATAAGACTTGAAAAACTTGTAAATGTT TTTAGAGAGAAT

TTACCTAATGTATTTTCGATAATTGCTTCTCGATTAAGGTTAGCGCTTATAGATGAT GACATTACCATA

TGCATAAATGCAGGAAGGTAATCAATAGCTAATACAGTAGAGTCTCCATACATTCTT ACATAATTCTCT

AAATAAGAGCGTACTTGTAATTTCTCTAAACCTTTTATTTTCTTGAGGTTATCAAAA AGTGTAAAGATG

TCTTTATATAGTTCCTTCTCGCTTAGATTAAATCCTTCTTCCATTTCTTTAATTAAA GATAATGAAGAAC

CATTAAAGCAAGCTTTATAGGCAATATCGTCTATTGTATTATTATAATTCTTTTTAG CCATTGCTAATAG

ATAAAACTTTGATAGAATAAAGGATACAAAGTCTGATTTAAAATCATTTAGGTTTAA TGAAAACATTT

TATCAAATATCTTTGAACCTAGTCTAGAATATGCAATAGATGAATTTTTCATTAATT CAGTATTACTTG

TAAATCGATTCCAATTTCCATTTAATTCATAAGTAATCATTGCTTGTTGCATTAGTC CGAATAATGTTTT

TGGTTGGATTTCTCCACCTGCATTAGTGTATCGTGAAACATCAACTAATACGTCACG TTGATTGTTATA

TCTTCTTTCAAATACAATCAAGTATGATGGAAATTTATTTGATTTATTTGATATAGG AATGATTTTTCCA

GAGTTATATAACCCAACAACTTTATTTTTAGTAGGATAATTAATTCGTCTATTAATA ATATTTATATTTT

GATCTAATACATCTTTAGATAAAACATCTTTACTAGTGTTTATTTTATTAAGTTTTA TTTTAAGATCATG

CTGAAAATTAGATGTATTGAAAATGGCGGAATCACTTAATTGTACCATTATTTCACT TTCCCTTCAATT

AATTTATATGATATTAATTTGTTCAATATATTAACATTTTTTACATTTATATATTAT AAATTCGTATAAT

GGAAATATAATAAAATTTTCAGTTTATCGGTTAAAATATTATTATATTATAAAATAA ATGTGATAAGG

ATGGATTATATTATGAGTGATAAAAAAATGCTTAAAGTAGGATTTCTTAGCCCAAAT GATGATAGGAT

TCGTTTTAAAGAAGTAGATTTTTCGAATAGTGAATCTTATGATAAAGAAATTGTGAG TGTTATTAGTCC

TACCGGAAATATTGATGCAGGAATCATGAATCTTAATGAAGATTTAGAAATTCATAA CTTCTTAATTTT

ATTTGATAATGAAATGTCAACAAATAAAGGAGAATATAATTTTACACATTCAATTAG TCCTCTTTTTGG

TGAAGTTGCTTTTGTAAAATTCGGTTATACTGGGGATAATATGGAACCAGTAAGCAT GTTAGATGATG

AAGCTGAGGTTCTCAGTGATATTATTTATCAAGAAAAAACTTCTGATCGAGCAATTG AATTTAAAGAA

AAAATTCTTGAAGAAGTAAGAATTTACGGTAAAGATGGATTTTTACGTAAATATAAT GAAAGTATTGA

AGAGGCGCAAAAAATGTATGAAGATAATTTTTCAGAAGAAGAAGAAAAATAATTAAG AATGGATGGT

GGATTATAATTGTCTAATATAAACGTAGTTAGTATTGCAGATTTACATTTTGGCTAA GAAAGATGATAG

TCGACTAATGAATGAATTAACAACAATATTTATTCCACAGATTAAGAATATTCATGA ATCTGATAAAA

TTGATTTGATTGTTATTGCTGGAGATCTATTTGACCGTATTCTTAAGTTTGATGAAG TTGGTGGAAAAT

TAGTATTGAATTTTATGCAAGAACTTATTGAATGGACAAATAAAAATAATATTTATT TTCGAATTATTC

AGGGAACTAAAACTCATGACTATAATCAATTAGCTGTGTTTAGAAAAGCAGAAGTTG ATAATTATAAT

TTTAAAATTTATGAAACGGTATATAATGAAAAATTGACTATCAATGAAAAAGAATTT AATATTTTATAT

TTACCTGAAGAATATCCTGAAGATATGAATGATTATTATAAAGAATTCTTTGATGTT CAAGAAAATAC

GTATGATATGATTTTCGGTCATGGAATGATCGATTTTGTAGCTTTCACTGGTTATGA AGATGATACTGA

AAAAATTGTAAAGAAAGCACCAGTATTTGTTGCGGATGACTTAATTAAAATTACAAA AGGACCAATAT

GTTTTGGACATATTCACGACTATCATGAATATAAAAAACAAATATATTATTCAGGTT CATTCTCCAGAT

ATTCTCATGGCGATACTATGGATAAAGGATATTTATATATTAAGTTAAACAGTGAAG ATACTTCTGAAT ATGAAATTAGTTTCTATGTTAATGAATTAGCTCCAACATATGCCACTATTGATTTAGATA AAATCAAAT

ATGATAATATGGAAGATTTAGCATCATTAATTAATGATAGTCGTGAAGAATATGACT TCATTCGAATT

AAATCAACAAATAATAATGATAGTTCTATTGTAAGAAAAGTTATTGAAAATAGTCCT AATATTAAAGT

TACTTTAAAGAATAAGAATAACGAAGAACAACAAGTTGATTCTAAATGGAACTTCAT TCTTGATAGAG

AGCTTGATACTGACGACTCTATAAAGAAATTTATTAAAATTAAATATGATAAAGATA TCGATATTAGT

AAGATTAAAGCAATTCTTAATCCAGAGATTGAAGATATTGATGATATTATTAAGAAT ATTTATGATAA

GAAAAAATAATTAATAATCTTTATTAAGAAGTGAATTATGAAAGGAATGTTTCATTG TGCCATTTATG

GATAATAGCGAACGTACAAGAGTCTTTAGATCTAGAATGGATGAATCTTCTCAACAA GAATTTCCATT

AAAGATTTCCGTATCATACTTATTTAGTTTAGCAAGATATGTGGTATATCCAAGTAA ACTTATCACTAG

AACTAATTTACGGAATTTAGATACATTATTATCAGCAGTCGATATTGATAGATCTTA TTTAGAAAATGA

AGTAATGGAAAAGAATGCATTTATATTCTTAAGAGAAATTAACCGTGTATTATTACA TCAACAATCAA

CAATAGAAACATTGTTTGATTATATTGATGATGAATTAAAAGATAGAGAAATCTCTG AAGATGCTCTT

CAAGAATGTGTAAACAATATTGCAATGGTGTTTGATGATAATTTCATTCTTGATGAT AGTGAAATATTA

AGCTTAACAAACTATGTAGAATCCAGATTAAAGATTATGGCACTATATCGTCAACGT GATAGAATGGA

AGGTATTTTAGAATTAATCAAAATGAATAAATCTCCAAACGAAATTAATACTGAATT TAAAGATTTTG

TTACGCAGAATGCATTACAATTAAGAAAGATTGAAACGAATAATCGAAGTTCAATGG ACGATATTATG

TTTAGCAGAGATAATGATCGATCAGTAGATTCACTAGACTCTACTATTAGACAATTA AGAAGTCCTAG

TAATAAATTATTAACAGGATATAGTAAGTTTAATGAAATGATTAATGGTGGTTTAGA GGATGGTCGAC

TTTATTTACTCTTCGGCGTTCCTAAATCATTTAAGTCTGGTGTTATGTTAAATATTG GAATGTCAGTATG

TCATAATAACGCAGGATTTAAGACAAAAGATCCTAATAAAGAACCAACCGTTGTTTA TTTATCTCAAG

AAAATACAATTATAGAAACAGTAGAACGATTATATGAATATATTACTGGTACTAGTA TTAATGAATCA

CAAGCTACTACGCAAGATGTTTTAGAATTAATCATGCAATATACGTATGATTGTACT GGTATTTATTTA

AAAATTATGTATAGACCAAATAAAAGTATTGATACAAGTTATCTATATAATATTTAT GATGAGCTTAAT

GAAGAAGGTAAAGAATGCATCTTTATGATTCAAGATTATACTCGAAGAATTAGACCT TCTGAAGGGCA

AAATCAAGATATTCGGATACAACTCGGTAATATATCTGATGAGTTCTGTACGTTTGC TAAGGAAAAAG

GTATCCCTGTAATGTCGGCGGGACAATTAAACCGTAATGCAAATGAAATTGTAGAGG ATGCTCTTGTT

AAGAATCGTTCAGACTTTATTAATAAGTTAGGTCGCCATCATATTGCAGAGTCTGCA ATGTTACTTGAA

AATGCTGATTATGGAATTATCATTGGTCGACAAGATTATCTTCCAGAGGGTGAAGAC GAAATTAATCG

CAAAAGTTATATGTCATTTAAACTTATTGCTTCTCGTGGGAAAAATAAGGATAAAGA TAGCAATATGT

TCTCTCAACCTTTTGAAAATGGATTTAAAATTGCAGAAGATATTAATCTAGCTGAAC CATTAGCAAAAT

TAAGAATTAATGAACAACAGTCTCAACAAGATATGGAAAATAGTGCTGACGAAGTAA TTACTTCAAG

AACTCCTAGATATAACAGTACTAGTAAATCTAGTAGTATAGTTCCGGGAATCAATAC TGGTAAGAGAC

GAACAAATCTTTCATCAACAGCATTATTACAAGAAGATGATATTCCGTTCTAAATAA TATTAATAACCT

AACATCCTTTTTTATAGGGATGTTAGGTTAATTTTTTTTTTTTAGATAGATTCGGCT TTTTGACGTAATT

TACTAAAATCGATATTAAACATTTTAAGTGTATTCATACTTTCTAGTATAGTATAAG ATATAATAGATT

CTACAATTGTCATTTCTGCAATATCTTCTTTTTTAGATTCTGATAGATCCATATTTT CCATTACGTATGA

TAAGCGTTCTTCACTAATTTTCATATATAATGATTTTTCATCTTTAACTTCTACATT ATTTTCATTGCATT TATCAACAAAGTTTTTGTATTTCTTCTCATAATCAATTACATTGATAACTTTATCTTCAA TTACGTTTAC

TGCAGATTCAATTAATGATTTCTCCTCATCATGGATAGAAGATACAATATCTCCAAC TTGGTCAAATGA

TAATTTCTCTTCATTTACATAATGACTGACTTTTGTCTTAACAAGACTTAATAAGTC ACCAAAGGCACC

ATGCTCTTGAATATTGATTGATTTATTTTCTACAATAGTATTAAAAGCATTAATACA TTCATTATAAAT

ATAATCAACATTCCCTTGTTTTTGAACTTCATCAATAGGAATAGCTCGGTATACAAT ACTTCCAAATAA

TGTTGGAGCTACTTCTTCAGCATGTTCATTAATTCGATTTTCCTTTTGAACCATCTT TTCACGTTCTTCA

GCTTCACGCTGAACCGTAATAGACGTTGTTCGTAGTAATTTACTCTTGTTTTCCATA TCTAAATTTTCTT

GTAATGCTTTTTCTTCTTCTTTCTTTTTACGGAAATATTCAGTACGTGCATTATTTT CTTCTCTAAGATTT

CTTGAACTTTCACCAAAGATACTAAGTCTTGACATTAATTTTCACTCTCCTATAATT TTTGCTATATTAA

TTTGTTTGATAAGTTATATTAGCTACATGCTCATATTTTTTACCTAGATTGATAGTA GTGACTTTACCAT

TACTATCTGTCGTTTCTACAATATTATCAGAAAGTGTTTTCTTAATATTGATATATT CAGGAACATATTC

AATGATTTCTTGTTTTGAGAGATCATTAATATTTCTTGCATTGTTAAGGATTTTTTG ATATTTATTAGAT

ATCTTTTCATCATAATTACCACTTAAACCGTTATATTCAATATAGCTAATGATCGCA AATTCTTCTTCTA

ACAATCTTAATAGATTAGATATAGGTACGATTCCATCAGTATTACAGGCTTCAATAA AGTCGGAAATA

AATTTCTTAATTGATAAGTCATCATTATCATTAACGGCTTCATATGTGTGAATAGTT AAATCAATTAGC

ATGTCAATGCGAGTAATAAGATCATACTTAACACTATCTCCATCCACTTCAGTATTT AAGTAATAATAT

TTAGATGGTTCCCAACTATTATAAAATTTCATATCAATTGTAGTATTATTTTCCAGT TTAGGAATAACA

TTGCTTAATATAGTGATATACGATTCAATTAATGTATATAAATAACTATATTCATAT ATAAAATATTGT

AAACTAATGAGCGGTATCATTTCAACTTTAAAATCCTTATTTGCGTCACTAACGTTT GAAGCACCTACT

CTAGTTACTGTACTTGTCATAATACTAGAAAGATTACGATATAACTTTACGGTAGAA TTAGTAGTTACT

GATAATGCCAATACATAATTATCAATATTTCTATTAGCATCTGGAAACTCATCATCA AACAATTCAATT

TCATTATTATTCTTTGTACCAACAGTCTTATATGAATTATCTTTATAAAGAATTCCG ATCTTAATATATA

GATCTTCATCAATAAATACATTATCTAGAACATCACCATTTTCATCATATAGCGAGT TTGATAATGATA

ATAATCCTTTATTAAATTTACGATTAGTTGATAATTTTGCAGTATAAGTAGACTCTG CTTGTTCTGGATT

TTCACGTTCAAATTCAAAGTAACCATACTTCTTATTAGAGTTTTTTGACATTAAGAT ACCTCGTACGCA

AATACGTTTATCTAAGTCGCCTATCGTTTCATTACTGTTTAGATCAAACTTAATAGT ATAAGTATCGGA

ATCCAAAGTAGATTCAAAATCATGAATTTTTGTTATATTAAGTTTATTGATAATCAT TGTTGTAGGAAT

TAAGTTATTAAGATAACTGTATGATGTATCGAATGTTTCATCAATATCCAGTTTATA ATATTTAGCACT

TAATACAGGATCAATATCTATTTTAACTAAGAATGGATTAGTATATACAAGCGTATT TTTATCATTAAT

AGATTTTTTAATATCATCAGTATATCCATCGGGAAGATGTTTATATTTTTTATCAAT ATAATCATACTGA

ATTAATGAATGTTCCGGAATTACATATCCATTAATATCGTCACCTAACAGTTGATCT GTAAAATATTTC

TTAGAGAAAGTTACACTACTTGCAGTATTTGTAGGAATAACCTTTTTATCATTATCA CGTAATAATAAA

AATGCATTATATAAACGCTGAAGAACATCATTTCGCTTTTTCATAAAGTTTATTGAT GAGTCATTTAAG

CTTGATGCTCGATCAATATTTCGGAAATAGATATCTAAGTCAGTATCCATAATTAAA TTATCTCTACCG

AGAGCAGTTTCAATAATTTTGTCTTTCATACCGCTAGTACTTAGTTTATCATTACCT CCTGAAGCAGAG

GTAATAGGAACTACTGTTGTGAGCATCTTTGAAAAGTTATTACTTGCTGAATTAGTA AAGTTAAATAAT

ACTTCTCCATCAAAAGTAAAGTTTCCTTCAGAACCTTTTGTAGTTAATATCTCAATG GTTATCTTACTAT TATATCTAGGTCTAAAGTTATTAACTAATGAAGAAAAAGATATCTGTAATTTATTATCAT CAACAAAC

GTATAATAACAGAATTTCTCATCAGGATTAGAAGGATTAAAGGTATTATTAAAGTAT GCGTTTAATTTT

ACTTTTTCGCCCATATACGTATAATATATATTGAATCCTGCCAATTGATCGTCAAAC TCTGCAGTATAG

AATAAATTATCACTAATATCTTCAGACAATATATCAAAGTCAAAAGAACTACTTTGA ACTTGGTAAAT

ATCTAAATTTAGATACATATACTTTTCACCATCAAAGATAGATTGATAAACTTTTAT CTCAGGAATACT

AAGTTCAATATATGGGAATGTACTTACTTCATCAATAAGATATCTAGCTGTAATCGT ATAATCATTATT

CTGATTTTGTTTCATTAATATTTGTACGTCATAAGGTAACTGGAATTTAAATTTACC CACAGAAAATTC

AAATTCTCGATCTAATATGATCTGATAAGTTTTAAGAGCTTTAACTTTGATATATTG ATCTTCGATAATT

TCTTCCCTTAATGGAGAATTTATTAAATCCTCTTTACGTATAACCATATTAACTAAC ATATGAGAAGGG

TTTGATAGTACTAATGGTACGTTATATAATTTTGCATAATTGAAGATACTATCTGGG AATGATGCACTA

TTTAAGAAGTGTTCATCATACAGTACATTACGATTATATACCGAGTTTTTAACCTCA TGGGCTGCAATT

TCATTAAAGTATCCAAAGAAACCAGTTTTTAATAAGTTTAATGCAGCATTATTTCCT TCAGAACCAGTA

GCAATATTTGTATCATCAATATTAAAATATGTGCTTGCCATTTTAAGCCAATGTTCA TGTACGTCATAT

GACGTTTGATTTACTTTAACTACTGAACTTGTATCTTCTTTAGCATTCTTCATAAAA GAAGGTACATCTG

TTATATCGTTTGGATTATTTTTATTTGCCATTTATTCTCACGCCCAATCACTATTTA ATTATCCAATACA

AATTTGAGTTTATATTTTTTCTTTTCATTATCACCATAGTTTTCAAGAACTACTGCA GGTCTATCTAATT

TTGTTAGGTCTAAGTCTGTAAAAAAGTCATTATATTTCTTAGCAGATCCTGGAGAAG TACTATATATAA

TACTTTCTGAATCTTTACTAGACGCTAATACTGGAGAGTCTAATGATACTGAATTAA AGTCCATTAATA

TTGCGGGATCCATATCTTCTTTATATGAATAAGCATAGTTAAAACTTAACTGAGCGA TATCTTTTGAAG

CTCCAATATCACTATTCATTACGTCATATGGAACATTTGTTGGTGAACATCCAGTGT ATTTAGTATAGT

ATAATATCGTTTCCATAACAAAATCTAATAAAAAGTAATATATGGAACTTGTATAAT CAATATATCGA

TTCATAAATACTTGTGGATTAGGTTTCATTTGTCCTCTAGATACTGCTTCAATATAG TCAGTCCATAATT

TATGAATCTGTAGTATTGTACTATTTTTATCTTCTTCAAAAGTAACGCTAGTTTCAT CAGCTACTACACT

ATTAATAAATGGTCCAGGAAGTAATTGCTTGTGACCATAAAACGTTTCATTAACTTC TTTAGTAATAGT

AGATATTCCTTTAAGTGACATGTTAATAAATCTATTAGTTAACGGTTTTATGAAAGA ACTATTTGAACC

ATATATAGATCCTCCGCCAGTCTTACTGGTTGCGTTCCCACCATAATTAAGCATATT TAATATTTCAGG

GCGATTATCCCTCATATATTGAAAAAAAGAATTCACATTTATATTTTAATCCGTTAA GTTAAGTTTTGG

AGTAGTAACAAATACCATAGGGAATGCTTTAACCATCGGTTCATTTCTTAAGCTATT TTCCAATCTATA

TGGATTAAAATATTTATTCTCATTTATATTATAATTCCCTATAATCTTTTTTCTAAT TTTCGTCTGACTTT

GACAAAAGTTTTCACCAACTTTCATATTAAGATCCTAGTATGTTATAAATTATTGTT AATGTATGCATG

AAAATATTAATTTATATTTTATTTATATATTATAAATTCGTAATAGATATAGTGATC ATCCTTATAGAGT

AAGTTTAATAATTAATATTAAGAAAAATGATTTATATTACTGTCCATATTAAATAAA ATATGACCTCAC

ACCAGTAATATAAATTCTGTAAAATTATTTGGCTTAACTCTATCAGCGCTATATAAA TTGAAATCATGC

ATATCGGAGAATATTAAATAATTCTTAGGGTTAGTCGATACAGTGAGAAACTATATC TATTAAAAAAT

ATTATTGTCTTACATGGGGGCGTTCTTATGTGCTATATGATTGAATAAAAAGAAAAA ATATGATTTAGA

AAAAACAGTAATAATACTTCTTAGTATTATTAATAAGATCCTATACTGAATAAAATT GAGGTATATGA

AAGCGCTCATAGGATTATTTATTAAAGATTATTAGAGTCACATTTCAATTAATTGAT CTGTGACTCTAA TAATCTTTATTTAATTTTTTTTTTTTATAACGCTTCCTATGATAAAACAATAAAATATAA AGTAATATTA

ATTAGGTCATCTAAATTGAAAAGGAGAGAGCGTAAATGTCAAAAAGCGTATTGCTAA ATTTGACTTCA

CTCTTTGGTGAAGTAGTTCTTAGTAAAAAAGGACAATCTGAATTAGATAAAAGTTAT AAAGAATTAGT

TAAAAATAAATCTGCTAGTAATAGTTATCTAAATACAATTAAAGGAAAAGCAGAATC TGCTATTATGC

AATTTCCTTTAGTAATTTCTAATAATATATCTATCGGAGTTTTAGATGGTATTCGTA GAAATATTGAAA

TTGAACGTGCTACGGAGTTCAGATTAGTATTGTCTAACGAACCAGTACAAAATGTTA CAACTAATGCG

GAATTCATGAATAAATATCACACTAACTTTAGTCTTGGAGAAGATATTTCTTCAGCA CATAATGAATTC

AATCAAGAGTCTAAATATATGGAAGAAAAATTAGAAATGCGTTCACTTAATGATTTT ACAAGATCTCG

TCAATATCTTAGAGAAGAAGGCGAACAAGATTTTGTTAATGCTAAGATTGATAAGGA TAAAGAAGAA

ATGAGTAGAGTTGAAAGAAGAATTCAGAATTCTCGTATAGTTTCTGATCGAAATGCA ATCTCTCCATT

AATTGTAAACAGTCCTATTACTTATAGTATTTCTAAAGTCTTTAATAATGATGGAAA AGAAATTAAGGT

TGATCCTCCAAAAATTATTGAAGGTCAAATTCGTTTTGGAATTAAAGCGGTATCTCA TTTAGTTAATAG

CGAAGATATTGTATTTTATCTTGGCGATGCCGCTAGACGTAGTAATTTCTTAGCAAA AGTAGTTCGGTT

TACTTCTGGCGAGCTTAAGTTTGGTAAGGATTTAATTCTAGCAAGTGAACGTAATAA ACGTTTAGTACA

TGACCGTAAAGGTTCTGGTGCTATTTGGAGAAACATGAATTATATTTCTGAACTGAA TAATATTCGTGC

CAATGTAGGCAATGTAAATAAAATGCAAGTACCTACTATTACTTTAGCAATTAGTAA AGAAGAAGTAG

ATTCTATTGCAGAAAAGACAGGAATCAATTTTATCGATAATCCTAACGCTACAGAAC GTTTGTTTAAA

GAATTTTACTTATTAGACTTCATGATCATTGATGAACTAAATGAAGTAGCATACAAA TTTAATCGTACT

GGAAAAACATATGACCGTTTTAGCCTACGTTCTTTAGAGATTTCAGGATCTACTGAA AGTCAGTTAAA

GAAACCTATGGAATTCAGTCAATTAAATAAAATGATTAACTCTATGAGAAAATAAGA AAGGATAGGT

GAATAATTCAATGCGTGGATTTAATAATCGTTTAAAAAATAAACCAACATCTTCTAA AGATGCCTTAC

AACAGTTATTAGTTGAGAGTGGCGGATTAGAAATGAATAAATATAAATTACTTTCTG AAGAAGGTAAA

ATTGGTATTAGTGACCGAGTGTTAATTACTCTTATGAAATCAATTAAACCAAAATTA GAAAAACCGGT

ATTTAAGGATATTACTAAGTCTAAAGGTGATATTACTAAATATAAAGCTTATGATGA TCTAGAAAAAG

TATTAAATAAAGTTCGTTCCGTTATTTCAAACAGTTCTAAACCTGTAGATAAAGACG TTAAAGAAAAT

ATGTCAAGCTTAGATACTGTTTATGATTTTGTTATTCGTGAAAAAGATGCATTTATG CGTGGATTTAGT

AATAAAGATTCTTTAGTAATGTCATTATATGTATCTTGTGTTTCGGTTATTGCAGAA GGATCATTAGTA

ATGTTTACAGATGCTTTAGAACCTACTTCCGATAACTTTGGAAATATTACAATTAAT GTTAAAGATCGT

CCGAAATCAATGAATAAGAGTTTATTTATTGGACTAAGACAATTTTCTGATATGGTT AATGCTAAAAA

ATTAAAAGATATTATTAAAGGTGGACAAATTAACTTAGAAGAAGAACTAGGTGAAAG CTTTGTTGGAT

CTCTTTCAGTATTGGGTAAATTCTTTAATAAAGTAGCAGATAGTATGGATGATGCTA AAGAAAAAGCC

CATGATGATGCAGATTCTCCAAAAGGTGAAGATAGTGCAATGATTCGATTCTTCAAA TCAAATAAATT

TGATAAAGCATCGGACGTTACTCGTAAGATTGGTAATCGAGTAATTCTACCGATTGT TGCATTATTATT

AGTATGTATGTTTATTCGCCTTGTAGTATTTATTATTTATCGTACTCGTGTAAACGT TGCAGACAATCTT

CGTAGTGCTGCTGAAGTTATTGATGAGAACTCTATTCGAATTCAAGATAAAAATGTA CGTGAACGACA

AGAAAAGTCTGCTAAACTATTCCGTAAACTAGCGGATAAAGTAGATGTAGACTTTAA TGTGGCAGACT

CTGGTGCTGATAAGGATATTCGTCAACAAGATGAATTAATGGCTAAAGGTGCAGATG ATATGATTAGT TCATATCAAAATAATGCTAACGAGTTTGGTATCTAAAAAAAAAATATCCCTATACATTCT AAAATTGA

ATGTATAGGGATATATATTATGAAATTTTACGTAATATAATTTGACCACCATTATCA GTAGTATTATTA

CTTTTAGTTGAAAATATTTCCGTCATTTTAAGAACCTGATAATCACCATTATATTTA TTATAATATTCAG

AATCAAACGTTATAGTGAATTTTTTAAAACAGTCATCGATATTTATATCCATATTAT TAAAACTAAATC

TTAGTATGGTATTATTTTCAGTTATTTGTTTAGTATATTCCTGTAGATTTTTATTAT CATATTTATTTTCA

TATACAATTGTTTTATTAATAGTACCATTTCTATCCTTAATACTATCTATTTGATAA CTGTCTTTTTCTAA

ACCTATCATGTCACGATTAAAAATAATATTATTTGTACCATATAATTCTGCATACAA CTCAGTCTGATC

CATAATAACAACACTATTAATCTTAGTATTAATATACTTATCAGTTATTCCATTTAA TTGATTAGTTTCA

CTATAAGTACCCATGATATTCTGGTCTTCAGGATTAGCATTAACTGGTATTTTAACG TCTATACGTATA

TTTCCAGACTCAACTATTTCCATAGAAGACATTGGAGTAATTACTAATTTATTATAT GACATAAACACT

TTTAGACTATCATTATATATTCCGTAAGCATTATTAATGTGGCTAATATTAGTTAGA ATATTTCCGGGT

ATTAAGGCTAATTGATCGTATATTTTTTGATTGTCTGGAGAAGATAGATATGTTCTT ACTGGAAGAAGA

GTTAATAATCTAGTAATGACTTCAGTAACATTAGTATTTGAATATATACCGCTAGTA TTATATTTATTA

ATAGATAGACATATTTCAGGGACGCATAAACATTCAAATTCTTCATACTGGTAATTT GTATCTGTTGTA

TCTTGGGTTAATCTATCACTAATATTAATCGCCCTCTTATCAATAATAAGCGGCTTT AGAATAATATCT

CCGAGAAATATATCATTAATATATGAGTTGGCAGTATCCGCATCAATGGATGAAGCT CCTAAACTTAC

TACAAATTTCTCAGAATCTTCTTGTAAACTTACCATAACAGATACTGGTAATTTATA GACTAATGATAT

CAGTGGCATTTTATAATTTTGAAAATCAATATCGATTTTAGTTAATCGAATATATTC AGAAGCATCAAA

CATATTTCCATCTGAGAATAAGAACTTACTACGTAGATTAAAAGTTTTTTTAGTTAT ACGAGAATAATC

CATTTATTATTTTTCACATCCATTTCATTCATTCAATATAGTAATATGTTTATTTAT TAAAATAAATTTA

TAAGAATATATTATAATAATAGATTATAATATATTTAGGGAGTTGTTTATATGGATT ACGGAAATTATT

TTGGCTATGATACAGAAAATATCGAAAAGATTATGAACTCAAAGAAAGTTAAATATA CAAAACTCATG

TCAATGGTAAAGAATTATGTAACGAGGGAATCTATTGGCAAGAATGTAAATATCTAT ATTGATATGAA

TACTATTTTAAAGCAGATATATAATAAGGATAATATTGAAATCTTTAATCATTTAAA GAGTGATAAAC

GTTTATTTATTACTGCTGAAATTATAAATATTATTGGTCACTATAGACATTTCTTTT CTTCAAGATTGAA

AATGTATACTACGTTTTATTTATTTACTTCTTTTGAAAAATCATCATATCATACAAA TATATATCCTGAT

TATCGTAAAGAATATTACGAAAAAAGATTGGGTGATAGAGATTTTGTTTTTTCAAAT ATTAATAAGATT

ATTAAGGATAATATGAATATCGTTAAGAAGATTTTAAAGTATGTACCAAACGCATAT TTGATTAATAC

AAAAGATAATGATCCTTCATTAGTACCTACTTATTTATTAAATGATAATCGTTTTAC TTTAGATACCGA

CTTGAATATTATTATTAGCAATGATAAACTTTTCAGACAAGATTTATTATATAGGGA TAATACGCTTAT

CTTAGAAATTAAAGGAAAAGATAATAAACGACTTATCGCTTATGAGGACGTTATCAA TACTATTGTAG

ATAGTACTAAAGGTAAAAGGGTTTATTCAGACTATAACTTATTAACAGAATCCATTA CACTTCTGGATC

CTCTTGTAAAGAATAAAGAATATAATATTAATTCAATTAAACGAACTAGTGAAATGA AAGCACTAGAC

ATTATTGAAAAAGGTATTAATGATAATATTATTTCTTCACAAAGCTATTATGACGTA GATGAAGCATAT

AATGATTTAGCTTTTTATCTTGGTGAAAATAATGAGGATGAATTTAAAAGAAATATG TCAATCGTTAAT

CATAAAATTGCAATGTCACATACTTTTAAAGATTTAGAACACGTTATACTTTCCCAA ATAATTGATCTA

GAGGATGATAGAGGATTAATGGAATTGAATGATAAGTTCTTTTCAAAATATCCTATT GTTATGGACTAT CTTGGTGAAAGTTTCTATGATCCGAGATAAAAAAAAAAAATATCCCTAATGCTAATATTA CTTAGCAT

TAGGGACTTATTATATACTTATTTTTTTTTTTTAGACTGATTTAATAAATTCAATAA TTTCCATTGACAT

TAAAACTTTATCCATATCTTCGATAAATACTTCATTATCATTTTCATCAATATACAT AAAATCATAATTA

TATGAGGTTGATAATGACATGATAAAGTTTTCACGTTGAACTAGATCAATAATACTG TCATACTCAGTA

AGAACTTCTCCATAGCTTTCTGATGTTACGATCTTATTATTAATCTTATTACTAATG CGATTTCTTTTTC

CAGAAGGAATAGTTTTACTTAGTAGAACTTTGGGTAAAAGTTTATAGTTATTCTTTT CAAGTTCTCTAA

TCATCGCAACTAGTAATACTAGTACTCTGGGTTCACGGAAGTTCTTAATGGCAAATC TTTTTGCAAAGT

ACATATTCATAAGTGAAATTTGGAATTCGTTTAAATGTTTAACATTACTACTTAAAC GTACAATTTCTT

CATTAGTAATATTATATTTTTAGATAGAGTCTCTCACATACTTATCGATAGATGCAT CATTAATAACGC

TTGACATTTCATTATGTTTATGGTACTGAATTAAAGAAAATTTATCATTCTCATCTA GATCGTCATCTGA

ACTAGAAATCTTGATTACTTTGAATTGTAGTGCATAATTAGAACGGAAAGCATATTC AATCTTTCTTTT

AATAACTACGTCTAAATACGATATTGATGATTTATTAATAGAAAGTTTGCATATAAT TGTACGTATAAT

TTCATCGGTAATTTTTTGGTTTAATATGTCTTCATCTACAGATATATTTTGCAAGAA GTACCAGATAACT

TTATCTTTGTATAACGTCTTTTTAATACGTGGTTCAACAATTTTGCTAATCTTAGTA AGAATATTAATCC

_{CTTTTTTATTACTAAAATAGCGATTAATTAATTTAAAAGTCTTTAAGAATAGTTG TTCATTGTAAGGCTT}

_{ATTTTTAGCATTACCTGAAGTAATAAGATATTCACATATAGTAGGAATTAACAAA CGTTGCATGATTGC}

AGAACGGATTAGTACTTTATTTGATTCATCAGTTACTTGTAGTTCAGGAACAATTTT ATCAGAGTTAGT

TCTACTATAATCATCTAATGAAATCGTATATGTAGAATCAACTACTGCATCAATAGC TTGTAATAACTT

ATCAAATTTAATAAAATCTTCGAAATCTTCAATAAATTTACTTTCAGTATAATCTTC ATCCATAAACAT

GTTTACTTTAAAATTTAATAGTTTATAGGCAATTTCAGGAACTTCATTTAAAAAGTA GTTTAAATCATT

GTAAATAATATGATAGATATTTGAATAAATTGCTTGATGAATATTATATTCAAATAA CTTTTCTTTACC

CTCTAAATTAGCATTCTCTAAAATAGAAGCAAAGTCTACAACTATCTTTTTGGGATG AGCATAGTTATC

TTCTGTAATATAAGTTGTAATGTCTTTACGATGTTCAACTTTTTCAATAGTTACCAT TTCGTTTGGATCA

TTCTCACTTTTAGGTAAAGATACAGTTACTTCTTTTAATCCTTCAATAGATATATAC TTATTTTTTAACT

TAAACTCTTCCTTCACACTATTACCCCTAACTTTTGTGTTATCAGACGTTATTGTCA CTCAAAAACACCA

ACCATTCTCTTTTTATTTTTATTAATAATATAATTGGGATGAGATTAATTTTTCATC ATATACATATCAA

CCTTTCTTATTTATATATACTATACCACACTTATATATAATATATAATTGAAAAGTT ATTAACGTTTATT

AATAGATGTTCTACGAGATTTAGATTTTTTATTACGATCAAAGATACTTTGTTTCTT AGGTTTATCGATA

TTTTTATTTTTAGGTTTTCCTTTACTTCTAATATCTTTTATCTTCTTGTTATGAAGT CTTCTATTCTTATAA

CGCTCAATTTCAACAAGCTTTCTTTCTGAAGCGGGTATATTTCTAGATACTTGTATT TTGTCAATAGGTT

TTAATCTTTCTAATGAGGGAAATGTTAATAGATTATTCTTTTCTAGATATATAAGGG CAAAATAAACAC

_{TTTTTTCAAATCCATAAATTTGGTTTGGGTTTCTTACTTTAGGTTCATCTACTAA AGATTTAATACTCAT}

TTTATTCTTAAGCCAATCAATAATCAAACCATCTCGATTATAAATATATCCATACGT AAACATAAAGTT

AGGATTATTACTATAGAAACTGATATGCGAGTTTAGAATAGAAACGTTTGTATTATT TTTGTCTATTTT

AATTACTACGTCATAAACCATTTTTTCTWYWMTAWACGTYKCAKAWSRRWTTYTAWA KWMATART

MCWAACTTTATSTTTACRTMTKKAWATAYTTMTAMWCKARATGGTTTSAWTMTTGAT TRGCTTWWK

WATAMAATGAGTATTAAATCGGTCATACATATTGGCGATAATCATATCCCGCCTAGC TAATCCTGCAG AACCTTTTCCTGAAGGGTTTTGCATAAACTGTTTTACAGTGATCATTTCTAATATACACC CCCTATTTAT

TAATTATAACATAATTTTTTGTTAAATTTAAAATAAACTTTTTTATTTTAAAAAATT ATTAACCCCTAAC

GTGAATGATAACTATCACGTTAGGGTCAACTTTATTATAAGCTAATTCGAATATATT GATTACTTGTAA

CCAGTAATCCAATTACTGAAAATGATGCTCTCATAATCTGAATATCCGTCATTACCG AGTTGATAATCT

TTGTTTCAGAGTCAGGAACATATTTCTTTTCTTTAAGATCATAAATCATTTTATTGT TAATACAACTCTC

AACAGTTTCATATACTTCTTCATCGCTAAATAATTGAGAGTTCTTTAATACAATTGC ATATGTTTCTTTA

AATGCAGAATATACTAGTTGTAACAATACTTTATCTACTTCAGTTAAACTTTCTTCA TTATCAATAATA

TCTTTAATTACTTTTGGAATTGAAATATTTCCTCCCGGAATATAACCGTAATCTAAA GCAGATCTACAT

GCAAAGATAGAATCTTCCAAGAGATATTTACGAGTATCACGTTCCAATTCAGATTTA CCACCAATAAA

TAACGTAGCTACTTTAGAAAGTAATCTAGCTTTACGATTCTCTAATTTAAAGATTTC AGAATCTACACC

TTTTTGATATACGTCTAAATTCTTTAAATCTTGAATATTAAGGTCAATTAATTCAAT TCGAGCATCTAAT

TCTTCTTGATGATACTCTCCCTTAATAAATTGAGTTGATCCACCAGTCATCGTTACT GTTTCACAACGAC

CAATATGTTCACCATAAAATTGAGCGTTATTTGTTTTACTTAAGATAAATAAGTCTT CAAAACCTTCTT

TACCTTTTTTAGTATTAATCTGAGTTCCTAAGTATATTGCTAAGTCTTCGAATTCTT CTTTACGAGTTCT

AGCGGGAAAGTCTGTAGCTGCAATTTCTAGGGATACTCTGGTATTATTGATCTTTTG AATCTTCATAAA

GTCAATAAATTCCGTTCTATATTCCTTCGCAACAATAACTAGACTTTTACCATTACC GCATACCTGACC

AATAAGATGGGCAAAGAAATCAATATCCGTCTTATCTAAACATGAATCAGTAATAAA TACATAAGGTT

CTTTGAACATTGCTTCAATCTTATTTGGTTTATTTGCAAAGATAGGGTCAACATACC CACGACTAGTTT

CAATACCATTTACAATTTCAAATGTATCCTCTTCAGAAGTAGATTTATCTAAATAAA TAAATCCTCGTT

TACCAATTTGTTTATAGATATTATAAATAATATTTCCGTCTTTTTCATCATTGTTGT TAGATACGGTTGC

AATATTACGGAGAATCTCAAAGTTATCTTCATTAATAGGAATTGATTTTTCTTTTAA TTTCTTTTCAATC

AGTTCACCAACATTATTTAATGAATTAATGATTTCTTTCTTAGGAAGCTTACCTAAG AATTGTGAACGA

TCATTAACCATTGGTTCTAATTGATTATATAATTCATTACTAACCACTACTGAAGAA GTTGATCCATCA

CCAACCTCTTGCACTAATGATCTTGAAATAGTCTTAATATTATTCAGAAAAGTAGTA CTAATAGTATTG

TTAAAACGAATCTTGTCTAAAATTGTGAATCCATCTTTAGAGATCTTAGAACCATAT AAATTATCTTCT

AGAATAGTTGTAGATCCATAATATCCTAAGGATTTAGAAAGAATATCACTAATACTA TTAAGTGTTTCT

TTAGCAATTTTTTGATATACTTCATCAGAAATTACATTGCTTTCTACAATATCAATT TTTTCCTTAGGTT

CAAGAATTCTTGAAATTTGATCTTTAATAATATTGCTCATACACTTTTCCACGCTGC TATATAAATTAGT

GAATTTAATTTAATTCACAAGAATTTAATCAACTTCGTCAACAAGTTTCTTATAAAT TCACAAAAAGTG

AAAATACAGAGGAAAACTCTCTTAAGTTATAATGGGTTTAGCCAACCCTTTCTGCAT ATATTTTTAAAT

TACATGCAGAATTATAATCTCTATCCATCACTTCATTACATTGATCACATGTATATA ATCTATCCGAAA

GTTTCATTTTTTTATCATTTTCTTTTTTATATCAACAACAACTACAAATTTGAGTTG ATGGAAACCATCT

ATCTGCAATAATTAAGGTATTTCCATATAAAATACTTTTATATTGTAATTGAACTTT AAAACGATAAAA

TAAAGACCGTGATATAGATTTAGATATTTTTCGGTTAGATAACATTCCTTTAACATT TAAATCTTCTAT

ACATATAGTGTGATAATTTTTAATAACGTAAGAAGTAAACTTATGCAGCCAATCATC TTGTATATTTTG

TATTTTCAAATAAATATTTTGAAGTTTGATTTTCACTTTATTATATTTATTCGAATT ATTGACTTTTCTAG

ACAAGATTTTTTGGTATAAAGAAATTTTCTTATATAATGGAATTAAATTTTTTAAAG GACTATTAAATC GGTGATTTTCTTCACTTATATCAAAATGACCAATATTTGCATCAATTCCAACTGTCGGAA GATTTTGAT

TTGAATGATACATACTATCATCAGTATCAATACAGAAAGAAGCAAAATACTGATTTG CTCTTTTTGTAA

TTGTACATATTTTAATATCACCATTAAATCGTATCGATTCAGACATTTTTACACCAT ATTTAAATTTAGG

TAAAAATAATCGATTATTAATAATCCTTATTGTACTTTCGGCTTTTCGATTAATCGT AAATGAACTTTTT

GCTTTTCGTTTATTTTTGAATTTAGGTTTACCTGAATTAGATGTAAAAAATCTCTTC CAACCATATGCCA

TATTTTTACAAGTATTATCAAAAATATTTGGGGGAAAATTATCCCATTCAGGTTTCA ATTTCCTTTTATA

TTCGTCTCGCACTTTTCGTTCATTAGGTTTATTGCCGTTAATGTACATTTCATTCCA TATATTCAAAGAC

ACATTATATGAATATCTTGAATAATTGAAAAAATCTTTAAATTGTAACTGCATTGTT TTGTTAGGATAG

ATTCTGATTTTTTGACTTATTATCATCTAAATCATCCCTTAAAGTTTTTTTATATTT TCGTAATCCGTATA

ATCGGCTAGAAAATACATGAATAATTGTCATAAGATCATCAACTAGTTCTTTTTCAG GAGAAGAACTT

TCTAAATTAATTACAGTTAGTGTTGTTCCATTAACTTTACATCTTTCTTCAATAAGT TCAAAACCAAAA

CGAGTTAGTCGATCTTTATATGTTATAATAAGTTCTGATACTTCTTTGTTTTCTATC ATGTCAATTAATT

TTAAAAAATTCTTTCGTTTAAAATTAATTCCGGATGCAATATCTGAAAGATAAATAT TAACAGGTTTTC

CACTATTAACTGAAAATGTTTCAATAGATTGTCGTTGGTTTTCAAGTTCTTTCTTTT GGTTACTAGTTGA

AACTCGATAATATGCTACAATTTTTCTTTTTTCTTCAGGTTTGATATTATTAGTTAG TTCAAAATAATCA

TCAACCATTTCGTCAGTATAATACTTTAGGCGTCCTTTTCGAATAGGTTTAATTATT TTTTCCTTTTCTA

ATGTTTCTAGTTTTTTCTTTGATATACGTAATTTCATTCTAAATTCATCAGAACGCA TAACCATTTAAAA

CACACTCCTTTTTAATTTATATTATATTGTTACATTAAAATATAAATTAAAGTGAAA AAGAGTGAAACT

AGATGATATTCATAATAAGTCGGCTAAATTAAATTCTTATTATAATTCCCAATTTTG TGTTTCCACATTG

GTTAAATAGCAGGACTATATCATAACCTATAATATTATAGGTCCCTCGTACTTCCCT TTCGGTACTCTA

CTTGCTTCGTATAGATATCTCAATCTATCTTATTCACCATATAGGTGTTACATTTAT TATTTGCTTTCGA

TAGTCTCTGAACGTTCACCCATCAAGTGGGAGCTTCGCTGCTAGATTTTCCATTAGT CCACCCTTAGCA

CTACGTTTTCTAAGGTTCACATTATTACTTCACTTAGACACTGATAGGTTTTATTTC AGCTTAGGTAATC

TTAAAGAGTTTTTTCTGTCTTTCGACTGCATTCACGCTTACCGTTACCAGTTACGTT GTAGCCCTTTAAG

CTTTAGGAGTTTACAAGCAATTCACAAGGTTTCGCATACATCTTTACAGATATATGG GAGTTTTGAATA

CAGGTTAATTTAATTTATATTTTAAACTAAACTCATTTAAAATCAATTAAACCATTA CTGCTTCTTTTCT

CCACTTTTTTATTTTATTATAATTGAAAGTACATTGTCATTTTCAATAATACAATCG AATTCTTCGATAA

AGGTATACATCTTAATATAATCTTTACATGAATCAAGATCAATATAATTATTAAATT TTAAGGATACTT

TTTTAAATTGTCTAATTTCTTCATCTTTGGAAGTATTGTTAAATCCTTTGATGATAT TAAATGAAAATTT

CTCTTCAAGATCATATAGTAGTAAATTAAGCTTTAATCCGAATTCAGAAT

SEQ ID NO: 2:. LPJP1.NL Recombinant Bacteriophage Genome Sequence>JGl l_062520-l_

LPJP1.NL (224,658bp):

TGACGAAAAAGCATGTCTTCTACATCTACCGGTACATCTGAAATATCTTTCTTACAT TTACTACATGTT

AATCCATGAATTGCATAAGAAATACCATATTTATCAGATTGCTCACTAATCATTTCA CTAAGACTCTTC

ATGTCACTAACTTCAAGATTACTAATGATCTTAAGAATTTGTTCTGGGTTTGTTACT TTTACAAATTTAA

GTTCTCCAGTTTTTTCCAATCTATCTAGGTCAGGAACCATTATTTTTTTAGTGAATA AAATTAGATCAAT ATAATCTCTAACTTCATCATAGCTTTCAGGTTTAATATATGATAGTAATGTTAATTTATC TTTTAGTGAA

GGTATTTGAATATCGAATACCATTTTACTTAACGGCATTTGGGAACGAGTGATCTTA TTTACTGCTGAA

TACTTTTTAATGACGCTTGGATCTTTAACTGTATCAGTAATTTGTTTTAAACGAGAA TATGTTTCTTCAT

TCTTAACAACAATAAGATTCTCATTATAAGCTTTAACATTCCTCATAACGTTTCCAC ATGATCCACACT

TAATATCAAAAGAAGTTCCACGTGGGAATGTTTGACAGAATAGTCCGTAAATTAAAG TATCTAGATCA

TAGATAGATGTAATGTCAATGAATGTATCCCAATCTAATTTACCTAGTGTAGTGGAA TTAATTTTACTA

AAGTATGTTTGATATTGACGTAATGTAGATTCATATGCAGAAGCGGTGCTTGATGAG ATAGAAAGCAT

ATCATTCATACGTAGACTCTCTACATGAGCAATATATGCTGATTGATTTAATGTAAC TTGATAAGTAGG

GCTTCCTGTTAATGCATATTTAAATTTATCAAAATTAATATCTTTAAATTTATCTTC ATCATCAATAATT

AATGAGTCGATATCTTTTAAATTATCAATTTTTGCTTTATCAAGAATATCTTTAACT GAGTCTTTTTTAG

GTTCTTGTTTAATTTCAGTTAATGTTTCATCTACTTGTACGTTGTTAATATTTTCTT GATTAATTGGGTCT

TTAATAGGAATCTCATCACTTGGTTCTTCAAAAATTCCTTTAATCTCTTCTTCTTCT TTTTTCTCATTATC

AGGAACATCATCAGGTATTGGATTTCCATCTAAAGGCTCAATGTCTGATGGATTATA CGCAAATTGTTC

TTCATTTTCTTGTGATTTTTGTTCATATTGATATTGTTGAGTCATTGCTTGTTCGGT ATTTTCATTTTCTC

CAGTATTATTCGTTACTGAGGAATCTTCTTCTTTCTGGTAAACATCAATACCTGTAC CAGAGAGAGATA

AGTTAGGATCAATATTCTCTTCTTTTTTAGCTTCTTCAGATTTTCTACGTTGCTCTG CTTCTAGAAATAA

TTTTGCTACATGTTGAGGATCTTCACCTACTACTTGGGCATGTAACATTGCTATTTC TAGATCGCTCATC

TTTTTATCGGGAATATTAATATTTGTAGGAATATTGTTATTTTCATTATTATCTGAT TTTAATACCATTG

TATATTTTACCTCCACATAATTTATATTATTTTTAATTATACATTATTTTTGATACA GTTGTATTTGTTTT

ATTATTGTATCCATATAATAATCCAAAGTTTAGATTAGTAGTAGTATTAGAATCTAC TAAATTAATATC

TATATAAAACGTATTTACATTTACGTTTGAATTACTAGAAAGAACGTTTTTAACATT TTGTATATTAAT

CTTTACAACGATATCTTGATGTACAATATATGATTCTATTTGATTTTCAATTTTACT TTGAAGTTCTAAT

CTAGTTTCCGTATCCAAGATTTCATATAAATATAATCCGATACCGATGCCCATATTA GGTTGGTTCGGG

TACGTTCCTTGCTCTATTATAATTAAATTTTGGATCTGTTGTGCTAATGCTTCTAGG TTTTCTCTTAATAT

TGGTTGATTGAAGTCATCCCTCTCTAGTATAACTTCAGGTCTGAATGATATATTTGA TTCATCCGCTTTA

AAGTCTGCCATAATTTTCACCACTTTCTATTTAAAGTATTCTATAAAAATCAATAGC TTTTAATTATAAT

TATATGTTGCAGTAAAAATTAACATTTTAAAAAATTATTTGTGAACAATATTATATA TAAGTTTAGAAA

AATTTTTTTCTGGGTTTATATAATACTTAAATATCACTAAATTGTTTAAAATACTCG GGTTGTAGTTCAC

ATTGTTGACTAACCATTTAAATAATATAATTACATTTAGTGATATTATACATATCTT TCATCATAACATT

ATTCTAAAAAATAATGTTATGATGAATATTGTTTTAATGAACATATACTTATTATAG ATATATTAATGC

AGAAAGAAGTGAATATTTTGAAACAATTTAAATGTCCATATGACAGAAAGATATTTG TAAATAAAAAG

GCATTATATGATTATATGGAAAAGAATTATTCAGATCAATTAAATGGACTATCTCCG GCTAATGCTTAT

TTTAATATCAAGTATAACAAAACACATGGTAGATGTATTGTATGCGGTAAGAATACA CCATTTAACGA

AACTACTGAAAAGTATGATCGTTTATGTTCAGATAAATGTAAAATTAAATATAGAAA GCAGTTTGTAG

AGAGAATGAAAAAAGTTCACGGAACAGATACTCTATTAAGAGATCCTGAAATGCAGA AAAGAATGTT

AGCTAATCGTAAAATTGCAGGAGTATATACGTGGTCTGATGGTAGTAAATTTAAATA TGTGGGTAGTT

ATGAGAAAGATGCGTTAGAATATATGGATAAGATATTAGGATTTCACTCTAAGGATA TTATTGTTCCTT CTCCAATAATCTTTGATTATACGCTTGATGGTAAAAAACATTTCTATATACCAGATATAT TTATTGTTCC

TTTCAACATGGTGGTAGAAGTAAAAGGTACTAACAATCATTACCAAACTAGGGATAG ACGTACTGAAG

ATGCTAAGGATAAAGCGGTTCTTAAGACAAAGTATCGTTATGCAAAATTAGTTGACA AGAAATATGAC

AAGTTCAATGACATTATTGAGAATCTTAAAGAATCAAAGGACGATAAAGTCCGTTAA TATAAATAAAA

TTTTAAACCCTCATTTCAATAATATATTATAATTAAGATAATGTATATTATCATATT GAAATGAGGGGA

TTTTATTGGAAAATAAGAAACGTAAATTCTTGGCACTGTGTGGAATTAGTGGTTCGG GTAAGAATTCT

GTTGAATCTATACTTGATGGTTATTATGATAATGTTAATGGAGTGTTTTTTAAAAAA CTAAATCAAGTA

ACAACTAGGAATATTCGAAATACTGATGAATTTAATAGTGGAATATATAGTTTTATA ACTATAGATATT

TATAATCTAATAAAAGAAAATCTCATTGGAAAAACAGTTATCGATAATAAATATTAT TATGGTACGCT

TGATACTAGTACTACAGATGGTTGTATTAATACTATTATTGTCAATGCAAAAGGATT ATCTAATCTTAA

GAATGATCTTAATAATAAGTATGGTGAAGATAACTATGACCTATTTGTATTGCAGAT TGCTAATAATAC

TCCTGTGGAAAGAAGAAATAGAGACGCAGAATTTATCAGAGGTGAATATAATGATTT AAAAGGATTG

TCTAACGCAACTCTTATAAATAATCCTAGTAAATGGTTAACTGTCTCTGACGTAATT AACTGTCTTAAG

AAAGAAGGTTTTTTGGATACATGACATTAGTTAGTCATACTAAGTTATATGAAAAAA CAAATTATCGT

AATAAAAGAATTAGCTATATTAAAAATACGTTGATTACTGAGTTTGATATAAAAAGT GCTGGTCTAAA

TATTCTATATGAAATGGAATATTTAGACCAAAATCAATATGAAAAATTATTATCAAT GGAAAAGTATG

AAAGAAACGTTACAATCGGAAAGATATTAAGGTCTAATAAAGAAATGAATGAAGCAT TATCATTTGGT

TTTTCAGAAGCGAGAAGATTATTTTTCGAATTAAATCAAATTGATGATTCAGAATTA TTATCTATTAAG

AAGGATGCAATATTTCTTATAGGTAGAAATAATATAAATATTAACGGTAATGTTTCT GAATTTATAAA

ATTTAGACCAAAGAAATCTTATACAACGTTTGTTGAAGTGTTAGACCGAGAACACTA TTTGAACTTTG

AAAGCGAAGAAATAATTTATGATATTAAAGGATACTCTAGTGATATTAAAGATATTC ATAATGAATAT

TTATTAAAGGATCTTCTTAATGTAATGAAGTTTGATTATGTTAATGATAAAGATAGA ATATTTGAATAT

TTAGCAGTTCTTAAGGATGACCTAATTAAATATAGACTTCCAGTATCATACTATAAT GATATTAAAGTA

GGAAAATATATTGTAGAAATGGGTAACGCATTATTTGATCTAGATAATATTAATGAT AATATTAAGCA

ATATTGCCTGTTGTCTAATAATCTTAGTTTTATTTTAAATCTAATCAATAAGACTCT TTCATAAAAAAA

AAATAAATAATATATTAAGGTAACGATCATTAATTTGATCGTTACCTCTTTTTTTTT TTTCTATGATCCA

TAATATACTATATATTTACAGATTTTATTTTCTTGTCAATCGTTAATGATACTTCAG TCATGATAAGCAT

AATCTTGCTCATAACATATTCCTCAATATGTTCTTCTGAAATGATGGTAGAAACCCT ATATTTTAAGTC

ACTAGACATTCTTTCTACAACTTCATTAGTACATGATATAACAGATTCTTCAAATTC ATCTGTAGTTGT

ATCGATATCTATATCATCACTAAGTTCACTCTGATCTTCATCAATAGATGTTTCAGT AGTCGCAGTATTT

TCTACATATTCATTTCCTTCATTGTCATACTGAATATTCATACCATTAATTGCAGTA ACTTCACTTAATC

TAGGAAGTATTCTATCAATACTTTCAGCAATTAAATTATTCTTTACAATCCGTATGC TAATATCAATAA

GAATATCTAATTCCTTTAGTGCTTTTTCACCATCAATATTATTATGCATCATTCTAT TATTACGGTTAGA

TTTAATAATCAATCTTCCAATAATTATATGTGTAATAAATATAATTATTAGTATTGA AGGTACTGTAAT

GTAAAATAAATTTGTAGTCATCAAATAAACTTCCCCTATTCATTTATTATTTATATA TAATTATTCATAC

TAAAAACTTGAATTTTATTTTCTTCTAAGAAAGATACAACTTCCTGAGAATTATCAT ATTCTTCTAAAT

AATATACTTTAGATATTCCTGAAGCAATAATCGTTTTGGCACAATTAAAGCATGGTG AATGAGTAATA AACATTGATGCGCCTTCTGTATTTCCAGAGTTTCTAGCCACCTTAGATATTGCGTTTATT TCTGCATGTA

TTTCATATTTTAATGACCATTTATGATGAATTTCCATATCTTCACATAAATAAAATT TCTTTCCTTGACT

TTCAATATAATAATCTTTGCGACAAATGAATTCCGGATGTGAAGTATACCATAATCC TTCTTTCTTTAT

GAATATATCATTACAGTTAGCGTATCCACTAGGGGTTCCATTAATTCCTGAAGATAT AATGGAGTTATT

CTTAACAATAATGCAGGAGACTTTCTTTGCAGAGCATTTACTTATTTCTGACATTCT TATTGCAATATTC

ATAAAGTTTACTTCGTTTGTCGTAATATAGTCATCCATATTATTATCTTCATTATCT ATAAATATATCTA

CCACTATATAACCACCGATCTTATTCTAATTATAATAAATTATTTGAAATGATGCAT TGTTTAAATACT

TTTAATTTTCCGAATGTTAATGTTAATATCAACACGATTTATAAAATTGTCAATTTC TGTATCTGTATTA

GAGAACATATTTTCAAAGATATCAAACTTTATAATTCGATAAAAGCTATCTTGACTT ATATAATGTGCA

ATATTATTAACAATATTATCATTATCTGTAAGATAAAGATACTTCACAACAAGACTA AGCGTTGTTAAT

ATTAGTCTGTATATTTCTTTTATACGATAATCGTTTATATTTTTATCTATAATTAAC GTATCATATGATT

CTGTCTGGAAGTTAAATTTATATGTTTCTTGAGAATTTACTTTCTTCATCAAACTAA TTATAGATACTGC

GTTTGATGGCATTTTTTTCACTTTTGGAAATATCAATTCTTTATTATTTATTCTTCT TTTTGTATCTTTTAT

TAATTCATCAATAAATTTTGAAAATTCGGCATTATATAACTCATCATTACTTAGATC CATATTTTTTTGT

AGTTCAATATACATTTTAAATTCTAGTTCCAATCTATTTAATATATGAACTTCATGC TTTGATAATAAGT

TAATATATAATACGTTTATTGTAGGAAATTTAATATTGGATTTATCATCAGTATCTA TATCAGTGGATT

CTATATAGTATGATGAGGGTGAAATATAATTTTTATATTTATACATATGCGTATATG AGTAAATAACTA

ATTCATTAGTATACGTAAAATTCATTAAATTATCATTATCATAATTATCCACTTCAA TATAGTTGTTTAT

TATTGCATCTTTTCGACTGATTAACGATCTTTCTTTATTATATTTGTGCATTATAAA AGAGATATATCTA

TTATTATTTATATAATTAGATGAATCGATAAACATGTCATATTCTTGTAATTCTTCA AAACATAGTTCTA

AAATATTTGCAAGCAATATTTGAATTATATTTCTATTATCTTTTATTTTATTATAAC CATAATAATTTTT

GTGACTTATCATAGGAATATCTGAAAATATGATGTAATTTTCAGAAGTAAGAAAAAA ATTAGAATTAT

TTAAATCATTGAAGATACCAGTAATTTTACTGATATCTTCAAGACTTATATTTTTAA ATTTTTCATAGTT

CCATAAATTTCTCACTTTAATATTATGGTTAGCATCAGTATAGAAATATTTAGTATC AATATTCATTAA

CTAATCACTATCCTTATATAATATTTTAGTATCGATATTTACTTTTGTTTTTAAAGT TAACGTCTCTTACT

GTTCCTGGAGGATTATTGATTGATAATCCTGCATTATTATTACTTTCTGTAAGAAGC CAGATAGTATAT

CCTTTAGGTTTCTTACAATCAAGCGTATTCTCACCAAAACCATCCGTAATAATAATA TTAATATCTGAT

CGAATATTTTCATTAATATATTTAATTGGAGCAGTCAATGTAGTTCCACCATAAGCA GTTCTTTCAAAT

TTACGTAATCTATCTTTCTTAGATAACGGATATACATCATGAACCATTGTATCAAAG TGAATTACATAT

AGTTTACTTTTAATATTTGAAATAATCTGACGAATTTGATCAAAAGCCCAAGCCACT TCTTCGTCACTC

ATTGATCCTGACATGTCGATAGCTACGGTAATTTTAGATTCACGATCCGGCATTCTT CCTAATAAGTCA

CCACGATCTGGCATTCTTCTATTTCTACGGAGATTAGTTCTTTTATAAGGAACTTTT AAAGAACCAATC

TTCGTACGTAAGATTTGTTGCCAAGGAATAACTTTTTCCTTATTAATATTTTCTAGA AATTTATTAATAG

AAACAGGAACTGATCCGGCTAAAGATAGTCGTTCAATAGTATTTTCGATATTTTGTT TTATTGAACGTT

GAATGTCTTCTTCAGAATAATCGCCGTTTTTCCATTTTGAGTGAGAAGAATTAGCAC TATTATTCATGT

TAATGCGTTCTTTCTTACCTTCTGAATCTAATTCATTACCTAGATCATTTTCATCTT TTCCGTATTCATGA

GATTTGCCAGTATTACCATTAGAAGAACCTTCTTCTTCATTTTCGCTGTCATTATCT CCACCATTATCAG TATCAGATGAATCATCATCATTATTCCCACTTTGATTACTTGGCATTCCATTATTATTTT GACCGCTTTT

ATTATTTTCATTAGCTTCTAATAATGCATCCATATAGTATTCAAAAGATTTATCTTT TTCCAAATCCTTA

TTATTAGTTAACATTCTTACATAATCTAGTGTAATAGAACCTTCTGGAATATCATCA ATATATTGATTA

ATAGAACAATCCATAGCAATATTTGCCATATGCATGAAGTCTTGATTTTTACTAATC GCCATATTCTTA

TATCGGAAAATATGATTATTTGAAATATGAAGTAATTCATGAGTAATAACTGCAATG AATTCTCGATC

ATTAAACATTAAAATTTTATATGGATTTAGATATAATGTAAATGTATCTTTAAATGT ATTTTCAGCATA

GCTAACTGCTGCCGGAGCAAAGTTCGGATCATGAACAACTTCTTTAATCATATTAAT TGTAAATAGAG

CAAAGAATTTGTCATCATTAATGTTATCACTAATTAAATTAGTGAATGTTAACTTAA TATATGCTTCAA

ATGCTTTTTCTAACTTTTTTGAAGCTTCAAGAGGTAAAAGCTTCTCCTTACCATAAT ATTCAAGAAGAA

ACTTTTTTAATTCTTTTCTAGTCATACTATTAGAATTATAATTATCTAAAGTAGGCA TTAATATCCTCCA

CCGATCTAATTATTTTAAACGTTTACTAATTTTTTGATTGATTGCGATATATTCATC ATATTGATAAACT

CTGTTATAGAAATCATCTGCAGTATTATTTACTTGTCGATTAAACATTGCAAAAGTA CTCATGATAACT

TCTTCTTCTCCCAAAGTATCTACAAATTTAATATAGTTCGCAGTCATTCTATCTAAA TCTTTTTTATTTTT

TACTCGTTTACTATCGTTACCCATTTCACGAACAACATAATTAATTACATAACGACT AAGTAGTGTTTT

ACGTAAGTTTGTTTCCTCTTTAATTTGGGTCAATAGTTTTTCATCTTTAGATAAGTT TGGGTTATCGATA

ATCAATTCAGCTCGGATCATAGGGTTTGTTTTGTCTTTTAGGAAATTAAAGAATAAT GAAGTAGCTTTC

GAACCTAGATTACCTTCAAACACTGCACGTAGTTTATGACTAATAGATACTGTATCT TCTGGGAATTGT

TTCATATGTTCATAATACGCATCAGAACTACGTTTCCATGAACGTGGAGTAGGTGAC TTACCTAAGCTT

GAACTATCTACAAATGACAGCAACTCAGGATTTGTTGCAATAAATTCAGAAATATCT TCATGAATGTTT

GGTCGAATATATAGTGGAGTAGAAGTATTTGCATCTACATATTCAAATTCTTGAATA GCCCAATCTAAC

CATTCTTCTGGATCTGGATCTAGTCTAAGATCTGTAAATCGGTCACGTAGGGCATAG TTCATTGTGTTT

ACTTGATAATCAATACCGTCACTGTTTTCATCTGTAGGATTTCCTGCAGTAATAATA TATAATTCTTCTG

GAAGAGAGTATTGATGAATTCTCCGATCAAGAATAATATTCATTAACTCTTGTTGAA CAGCTAAATCT

GAACGGTTAAGTTCATCGATAAATAGTAATGGAATTTTTCCATTATCTGCAATCTTA TATAGTTTACCA

ATTGTACTATGAATAGTATATTCATTTTCTTTAGGTTGTTCTTCATTTTTAAACCAT GTTTTGATATTTGT

AAGTTTAAATTTATTTTTAGGTTCTGCAATATGAGGGATACCGGTAATTTCTCCTTC TTTAAGTAAGTTA

CCATCAAGCTTAACAAACTCAATTAAGTCACCATTTCTTTCATTATAACGTTCAACA AATAATTCAGCC

AAACTAGATTTTCCGATCCCTGCATGACCTTCAATAAATGGTACGCTTCCTGAAGCT ACCACTACGCCT

ACTACATCTAACAAGTCTGACATTTTCATAAATAAATTCCACCAATCTATATTTTTT ATTTTATTACTAA

TTTATAATATATATTTATAAATTATTTATAATTGTGTTTGTCGCAGTACTAATTTTG GTTAATGTTTCTTC

AAGGTTTAAAAATACTTTCTTATCATCATTTTTTGCTTCTAATGCAAGATCGTCACA TCGCTGATTATAT

TCAATAAAGTGAGGTAGTAATTCTTCTGGAATATGTCGATTTCTTTTTGATGTACCT TTTTTAAATGAAT

TAGTAGTATGTCCTTTAACCCACGTAAAATTAAATTCATATTGAGAAGAACTATTAT TAATAATATTTA

CTAATAACTTCCACATCTCAGCATTCTTTACTGGTGTTCCTGAACTACTCATCCAGT TTCGATTAATCCA

TCCAGTCATATATTCTGTAATACCTCTGATAACGTATTGACTATCTGAAACAACACT AATATTAAACTT

TTCTTTATTACCATTCTTATAATTATCTCTCATAATATGCGCTATTCCATAAATAAC GGCTAATAATTCA

TTTTGGTTAATTGTTGAATCATGAAAAGATCTTTTAATACTGTATAGCGTATTAAAT TCGGTGTCAGTA ATATAGCATCCAAATCCTCCATACATAGGCTTACTGGGGTCTTTCCTACCATTATTAAAG CTACTTGCA

TCCGTAAATAAATATATGTAATTTGTATTATCGTTGTCCAATATATTTTCACTCCCA CGTTTAGTTATTT

CTTTTCGCCTATATTCTATTATTGTAATTCTAGAATAAAAAATTAATTATAATAAAC AATATAATATAA

GCACTTCTATAAGAAAGGTCTGATATTTATGAAAGTTCCAAATAAGAATATAATAAA TGATATTATAG

ATAAGGAACTAGAAGAAAATAAAACATTTGTAGTAGATACTAATGAATTTGATACTG AGAATATGATC

AATAGTGTTGTTCCTAGTGAAGAAAAATTTAATAAAGCTATTGAAAAAATTATTCGT AAGTCTAATGA

ATATCGTAGATATATCGGAATACTGAAAAATAATATTGATCTAACTTCTTGTAAATT TTTGAAACGTGT

TGATGTTTCTGAAATAAGAAGAGTTAATATTGAAATGCATCATTACCCATTTACTCT CTATGACATCGT

ATCTATGCATCGAGAACGTATCAAGCAAGATTTAGGTGAATTTTATTCATATGATAC ATTCACAATTGC

AGAAAATATTATGAAAATGCACTATGAGAATAAAATCGGTATTGTACCTTTATCATA TACTGCTCATG

AATTAGCTCATTCCGGAAAACTAGTTATTCCTCTTAATAAAGATTATGTCTTTGGTA ACTGGCAAGAAT

TAGAAAAAGAAGATATTATTATTACAGATAGTATGCGAAAGCAACTAGAAGTATTAG AACAAATGAC

AAATAGTATTGAGTCTGGAAGCCTTAACTCAAACGAAGATCTATTTAGTAATATTCA GACTGTAATCA

ATATGAAAAGTTCTGGAATACCAAATAAGATTATAAAGGAAAAATCAATCATTGAGG ATATTAATAAT

CCTGAAACTGATGAAGATATAATATAATAAAAATCCCTTAACGTATAATAATACTAT ACGTTAAGGGA

TATAATGTTATATTATGATTTTTTGCCATTAACTTGATCTAATAACTTATATATGAA TAATTCTTTATAT

ACTTTCTGATCTCTATTATATTTATCAATAGTTGCTTTTTCATCATCAGAAATAACT TCTGTACTAAAGT

CTTTAACTTTAATAACCATATCTAACTCTGTGTTTAAAGATTCTGATTTTAATACGA TATGGAATAAAT

TTATGAATTTAGTATTTTCACCTTCAATAAATTCATAATTATCTAATAAAGAAATTT TCTTATCAACATC

AGAAGAACTAAATATTTTTCCAAAGAAATCATCAATATATTGATTAATTGATAGTTT AATAATTTCTTC

TTCACTATAATTTTTATTAGTTGGAATATCCTGAGTGTACCAAATTTTTTGAATTTT ATCATGGAGCAAT

ACATTAAATACGCCCGGAGAATTTACCATAATATTGCTAACAACAAAGCTAATACTA AACGTATATAC

CTTTGGCTTAGTTTCTAATTTATCATCTGAGTTACATGATCCTTCTGATGAAGTAAA GTTATAAAATGT

ATTAAATTCTTTTACAAACTGAGCATATAATCTTTCAATAAAATTATCTTCAAAAGG TCCAAAATCTGT

ACTTAATGGAAGTTCAAGGTCTCCACTCTCCATTAAATTAATTGCTTCTTGAATTGA TTCAATTAATAT

ATCAATCTTACTATTTACTTCATTATCAATACGATCAGTTACACCTTTCGGACCATA GATATTTAACGTC

ATATATTCATTATTGTTATCATTCTTATTAAGTACGTCATATGTTACACTAGTAATA ACTTCACAATTAC

GTGAAAAATCCAATTCTTTATCAGTGATATCATCTAAATCTTTGATATCACCAATAA TTCTTAAACTAA

TAGCATCCTCAATATTAGGCATCCTAATTCCACATCCATTTCTTTTTATTTGATAAT AATTTATTAATAA

ATAAATATAATTTTTTACATTCATTTACAAGATTATACATTCCCTATAACTATGATA TATTCAATAGTTA

TAGGGAATGTATTTATAATTAATTAGTGCATTGTATTAATATATTGTATATACGATG AAGCGTTATCCT

TTATTACATTATCATGTTGTCTTATTTCATATTTCGTTAACATGATATTAATGAAGA TATAAGTTATAAT

AAAGAATATATAACTAAGTATTAATAGTTTTAATAATAGTTTATTTTTAGTTCGATT ATCTTGGTTTTCA

TCAGTATCTATATTTTTTCTTAAATTCTTCATTAAAAAGTCCCCCTTTTATTCTATA TATTATATTGTTTT

TTAATAAAAGCGTAATAAACGAATATATAGACATATATTATAATTATGATAAAATAA TAAATAATATA

AAGAAAAGGATGATATTATAATGAAAAAATTTGTACAAGTATTATTAGTAGGAGTTC TATTAGCAGTA

GCAGTAACAATTGTAACTATTAACGTTACAGAAAGTAATAACGGTACAATGCAAAAA GAATTATTACC AAAAGAAATTTTAAATAGACAATAGTATAATTACTACTATTGTCTATTTTTTTTTTTTAG TTGATTAAGA

ATATTTTATCATAATCTAGATTATCGTTGAATTCTAAAAAGAAGTCCCCAACATTAC TTACTGTACATT

TTCTAATAGAAGATACTCCTTCATCTATTGGTGTAGTATTATTTACTTCTAGCGCCA TACTATTATCACT

ATAAACTCGGATAGATATTTTCCAAGAATAGATAACTTCTACATTTTCTTCATTTAA TACTTTTTGTATC

ATGTATAAGTGATATATATTGTCATCATCCCTCTTCATATCGTTTGGGAAGATGTAT CCAATAGTTTTAT

CATTCTTATCAAAATAAAAATTTTCCACAATAAATTCTTTGACAAGATTAGTATTCA GTAATTCAATAG

CGTTATTTAAGAAATCTTGTCTAAATAAACCTAAATTATGAATATTGATTTCTAGCA TATTATAATCCA

CACCTTTTTCTTTTTTCTTTTAAGATATTAATTCATTATTAAGATAAATGTTTACAC TAAAGTCATCTTT

AGAAGTATTATTTATTTCTAACGTAATAATGTAATCATTGTTAGCACTATAAAAGAT GTATTCTTTTAT

ATACCTAAAATTATGTTGTTTATCAATAAATGAATCAATCGTGTTTGATGTAATATC CCCCTTATAATC

TTTGATATAATTCTTATCAAAATATATTTTTGCTTTATATATCTTTTCTTTAATATA TTCAAAAGATTCTT

TGTTATCTGCAGTAATTGTAACTTGATTATTTAGAAATTTGTTATAATCAATATTAA GTATATTTACTTC

ATTATGATTATAACAAACGTTCCATGCAGTAAATATTTCTTTTGAAATAAACTCAAA AATATTATTATC

CCCACTGTTATTCATAATAAATTTCCCCCGATATATTTATTTGATATAGTAAGTTTT ATTCTAATATTTA

TTTAAGTTTATAATGATATATTATAGATATGGCAAATATATAATATATATTTTAATT TTTCATTAACAAT

ATTTTAAGGAATAAGGAGTGCTGATTAATGTATAGATATATACGTACAAACGGTTCT ATGCGAAATAA

ATTGAAAGAAATGAATATTGATAAGAATGACAGTATCTTTGAAAATACTGTTAAGAT TATTAATGAAT

TAATAAATCATTTCTATTCAATAAGTGAAGTATTTAACTTCATAGAAAAAGAAAATA TTCATATCAATA

ATGAAGTGATGCAATATTTAAGTTCTGATGAATTTTATAAATCTGCATATACTTCGA AAATAATGATGA

AGAATCATATGTCTAAACATTCATTTATTCGCATGATAAAAAATGAATTGTGTTATC GTAATATTAGTT

TTATTTTTAATGATTCATTATTTACTAATGATGATATTGCCACGATAATAGTTAGGA ATGATCTAGCTG

AAATACCATTTGATATTATGGTTAAGGAAAATCCATTAAGCTTGAAAGATTTTAAGA AGACTTTAAGA

TATAATAATTTAAATGATCATGAAAAATCTATTTTAGAATTACGTAATATTTAAATT TATTAAGAAAAA

AAAAAGATAACTATTGTAATTTTAATAGTTATCTTTTTTTCGGATCATAGAAATATT TTATATATTATAT

AGGATAATCATATTATATATCTTTAATGATGATAATCTGTTGGCTAATTCTGGACTT CTTTTCTCTAATG

AATAGATATCGATAGCTTCAATAAGATTAATTACTTTAATAAATCCTAGATTTCGAT ATCTTTTATTTAT

TAAAACAAAATTAAGTAATTCTATGAATTGTATTAATCTTTCAGCATGATACAACGA TTTTATTTTATA

TTTTTCTTCAACATCAGCGAGATCTAATCCATATTCTTTGTAGTAATTTTTCTTTAA TAGCGGCTTCATC

CTACGTATCATGATACTAATATATCTATTAAGTTCATTATAGGTAGTTTTAGTATTC TTATACACTGCCA

TTTTATGAGTTTTAAAGTAGTTATATAAGTAATCTATTATATCATTAAAGAAATATT CGTTTGCATAAA

TAATCTTTATAAAACTAGACTTTGGCATAATAATATCTAATATTTTAGGGTTAATCG TAATCCGAGTAT

TTTCAACCCTTGATAAGAATTTAATATATGTTTCAGTTATAAATTTATATACAACTT CTGATTCAATATT

AAACTTTTCACAAAAATTACATATGACATCATTGATATCATACTTATTATCACAACA GAAGACGTAAG

ACGAAATTGTATACAATAATATATATTCAGTATTATTATTATTACTATGACTAATAT TATCATATAAAT

CACTTATCATGATCATCATATTTTCAGGTTTAATATCATATAAATAGAATATATTTT GATAGTATGATA

ATATTTGTTGACTTTTACGTTTATTATTCTTTAATAAGTACGTAATAATATTCATAG GTAATAATGTAAC

CGATTCCGTATCTTTTTTATCTAATGCCCTATTATTACCTAAGTATGATAAGATATC GATAATATCACCA AAGTTAGAAATATCATTGTATATATCTAGTATACTTTCAATGTTTTCATTTAATGACATT GGTTGTAATT

TATATTTATACGTTATCATAATTTGTCACCTGTATTCTTTTCAATGATATTTCTAAT TTTATTATTAGTAT

ATTCATCATTTGAGTAAATTCTAGGTAATATCTTTGGTTTATTCTTATTAGAAGGAA GATTATCAATTAT

TGAAAAAATTGATATTACTTTATTAATAATATTTATAATATTGGTATTTTTAGATTT CAATAACTTATTA

ATGTCATATGATAATAATTCATTATCACTATCAAACTTCTTATAGAATGTAAAACCG TACATATTAATA

TTATTTTCTAGTAATATTAACGTATCCATAATATTATTATATCTTACGTCATCCAAT TTATCTGAATACT

CCGTTCTCATAACAAAGCTTATTACTTTAACAATAAAATCAACTACGTTATATTTAT TTTTATATCTACG

ATATATTCTAGGATAATTGAATATAGAATTGATAAAAGTTGTATCTTTATACGTTAT ATAGGATACTGA

TATAGAAGGGTCTCCGGTATCAATAATTCTAGTAATATTTTCATATTCATCATCAAT TATATTATCATTG

TTAAGATATTTTAACAATATATATTCAATATATAGTAAATTCATATTTAAAAAAGGA TCTAATATACAT

TGAATTTCATTAAAATTTTTAATATTTATATCATATCCCTCATACATTATAATATTT TCGATAAACCTTG

_{ATTTTTCAGTGCGAGAATAATCTTTAATTTTACAAATATTATTTTTTGTTAAGAG ACATTTATACTTCAT}

TGTATTGTTATTAATAACCATATCCCTAAAAATTTCTTTTGTATCTTTTGTAGGTTG ATCTACATATTTA

GAAAATTTACGATTAAAATCAATTGTATCCCTTAATGATTTTGGATTATAGGTTCGT GAATTAATTTCT

AAATATTCTTGAATGTCTGTATTAATTGATATACTATTTGTCACGCTATATCACGTC CTATCATTTATTA

TATGCTTAACAAATTAATTCGGCTTTTCATTAACTTACATAATTCATCTATTCGTTT AATATTATTAAGA

GTGTTCTTTCTTATTAATGAATTATGATTATCCGCACTAACATTATCTTCATATCTT CTAAATAATTCAT

AATTATTATTAGTATAATCTATAGAATCCAAAATTTTAATACGTGCATTATTTTTTA CGCTAGTCATTTT

ATTATTATTAAAATTAATATATAAGTTTAATAATTCAAAAATAATGGATATTCTATC AATACTGCTTTC

AAATAATATTAGATCATCTTTATTGTTAAAATTAAGATATCTAGATATTCTTAATGC ACTATGAGGGTC

TATTCCGATAATACTGTTAATTGCTTTTTTACTATTAAGTATTATATCTTTCTGATT ATCTGTAAAAAAT

TTAGAATAACCACTACCATATATTGTATTGAATATTTTAGCCATTGATGATTTACTA ATAAATTTTTTAA

AATGTTTATCATCAATATCTCTAACGCCATATATCGCACAGAATAGATTGGTTGAAT ATAGATTCATTT

TGTCAATCATAGTTAAATATTCATTATCTGTAATTGTAGAAGATTCTGAAATGCATG TTTTAAACTTTTC

AGATATCCTATTTCTTATACCGAAGTCAGGATCATCGTCATTGGATATATTGTTATA TGTGTCAAATAG

TCTAAAAATAATTTTTCTAATGTATGAAGAGTTTATTTGTAAATTACTACTAGTATA CTTATACTTCTTA

CTAGATGGTGATATAATAAAGTCAATTAAATCGTCAAACAGTACACTATACATGGAA TTATTATTGAT

AAATGAATCATATAATTTGTCAATATTCTTCTTAGTAATTATATAATTACTATAATT CATACTTCTTTTC

GTATATATATGATTAATATTAACATATTGAGTATTATCCATAAAAGTACTAAACAGT TTATTGTATATT

ACGCTTGACCTAATACTATATTTAAACATAATGTAATCCTTTCTTAAATATTAATGT CCTTAATATAAT

GACGTAATAATTCCTCGGATATTCCTAGTTCCTTAGACATTACTTCAATAGGTTTGT TAAGATTCTTTTC

AATATAGTCTGTTATATATTGTTCTGAACTACGTGAATTACCTACCTTAATATCAGT AGTACTTAATGG

CATTTTAAACCCAATAGTTCTTGGGTTAGTAATTTTTTCATATTCGGGAACTGGATC ATTCTTAATAATA

TGGTCTGGTAGTTTCATATTATGTTTTTCTAGGCTACAATTATCCAATCTTTTAAGT TTATCTAATGATT

CATTAGTAATGATAATCATTAGATCGTTTCTACTTAGGTCTACTGACATTTCTTTCA CATTTTCATCATA

AAGTAGTGTAGACATATGACTAATAATATCATGTGAATTTTCCAATGTAATATTTTG ATCCATATATTT

TCTAATATATTCGACTAATTTTTTCTGCATATTCCGATTCCACCAATCTATATTATT TATTAGAGATTAT ACGTATATCCATTCAATTGTTAGGTTGTTTAGAATTACCTTCATTTAGTTTTATATTTAA TACATATTGA

ATATTGTTTCCTTTATTAAATTTAATGTAATACTTAGTCATATCACCAGTAGTATTA TTAATAAGTCTAA

TTGAATAGGATTTCTTACTATGTTTATTAATATGAGTATATAGATTATCTTCATCCT CTATAATGATATT

CTTTTCTGTAAAGTAATCTAATATAGATTCTATTCGTTTTAATTTATTCATCCTTAT CGATAATAATATC

GATAAGGATGAGAATAATATAGTTAACATGATAAATATAATCATATATCCATCGTTC CTTCCATATCTA

TTTTATGGACATTCATTAAAGTAATATCATACTTTTTAACTTCAATATCAATTGCAG TATAGTTTACCAT

AAATGTATATCGATTCTTTCCAATTTTACTAAGACTATTATATATCTGGATTGAATA TTCACGGATATTT

GGAGAAGTTATTATATTCGTATTCATTTTATTATCATATTCAGTTAATTTATCAATA ATTGAGTATGATA

ACATGATTTTTTTATGTACAATAGATCTGTACACTATTGAGACTATAAAGATTATAA TCATAATCGATA

ATAATAATATCATTTAAACATCCTTTCTTATATAGATTTATTTAATTTTTTGATTAC TGATATACACAAC

TTCTTTAAAGTCTTCATCATATACTAATTCAAATTTATCGTTATTGTAGAAAAAAGT GTATGTATTATG

AGTCCTATTTAAAGATCTTTCACAGTGATATAACAGATCTTTAAATACATTTTCCGG ATTTACATAAGA

TTCCTCCATAACATTTTCATATCCAGAAAGAATTAAATAATTTCTAATGTCTGGATA GACTTTTTCCTTA

AGAAACTTTGGATCCATTCTTTTTCTAAATTCAGCCCCAAGAATATAATCATTTATA GAATCCATTATC

TTATCAATAATTAAAAATCCGATTAACACTAAAAGTAATACTCCTACAATATTAAAT AATAACATAAA

TTTATCACTATCCTTTTCTTTTTATATATATATAAAAATCGATATCACTCCATTATA GTAACAATTATTG

GAGTGATATCGATTTAATTTTAAGTTATATACTAAGAATTATTTCGTGAGATAAATA TTTCTTAGTATA

ATGAAATAAACATGCTTTAGACTAATAATAAGATAAATTGTCAAGGGGAATTTGATC TTTATACATTA

TTTTCATTTAATAACAAGTTTATTTATAATTCTAATTATTATATCAGAATTATAATA TATTATTAAAATG

TAACTATAAATTTTTATAATTATACATTGATAATCATATCTACATTAATATTTTTCT GTTGAATCATTAG

ATTAGAATTCTTTAATGTATTATTAATTTTATTAATATTTAGGTTATCCGACTCAAT ATATTTGTTGATA

AATACATCAATGTATGCTTTTGGATTATTCATTGAATTAATAATCGTATCTTCCATA TTATCAATAGGTT

TAGGAGATATGACCATATTGATAATAGATGACATTTCATTAGTCATTCCCGCTTCAA TAGTAATCTTAT

CAAATATATTTTTTTCATCTTTCCATAAGGTATTATCAATATTCATTTTATTAATAT TGAATTCTTCTAA

AATGAAACAATTGTTTTCTAATACATCTTTTATTTCATGAGTTAGAGTGATAACGTT TCTTAACCAAAA

GGAACACTGTTTATTAAGTTCTTCTAGAATTACATTCTTTTGAGATATATTTTCCCT TAATTCATCAATA

TCCTTGGTGTAGTTATCATATCTATTTTTATATAAATTATATTCATCCATATTGGAT TCTTCTAATTTTAT

ATCCATAATTTCAGAAACAGCATTTTTTGCATCTATAAATTTAGATATCAATTTTTC AGATCGATTAAT

AGTGAAACCATTAAAATATTCTTTTGCCTTACTATTAATACATAAATATGTATCATA TAGGAAATTAAT

AGTTTTTTGTCTATTTTCCCTTAGCGTATTAAGATCTTTGTTATTCAATGATTTTCT AAATTTAACTGCTA

ATTCATAATCATTATCGATATTTGTACCTTCAGTGCTGATGATATTATAATAAGTAG TAGTATTCTTTTT

TAAAGGTTTATTGATAATATTTAACTGAAATGTTCTAATTTCCTTCATACTTACTCC CACCACCATTATT

ATCTAAATATTTATCATACTAATAATATTATCTAATTTTTCACTTTTAACAATATTT TCATTTAATACTA

AAACATCATTTATATATGGAAAACATTCTGTAATGTGTTTAATTATAAATTCTGACG TAATAGATCTTT

GATTCATTAGTACTTCTTTATGATTTAATTTATACCAGTATATTTCAATAAAGTCAA TTGACAACTTTTG

TCTTCTTGATATAATATCCCAACAATCATCATCAATATATACTGATATAAGTTCATA TAGCGTTTTTTCA

TCAAGATTAGCATAATAGATATTCTTCTTCATATATTGGGAAAACTTTATTAAGAAT TCCTTACTATAG TTACAATGCATAACAATATGACTATCCCAAGGAATAAAATCTATATTTTGAGAGTATTCT TCAATTGTC

ATGTGTTTGTATATACTATGATCAATATATTCCCAAAATATTTTAGTTTGGTTTTTA GTAATAAATTTCA

TATACATTTTATTATATTTCACCCGATAACTAAATCTAAACCATTCAGGATCATTTA TATCTTCTTTTTT

AGTCATATCAAGATTAAATAAGACCCCAATAAATAATCTTAGTTGATTTATAAATCG CCCTTTATACGT

GTCCATTATATTCAAGTTATTCTTTTCCTTTCTTAATATAATTATATTCCATTTATA TATTAACTATTTAT

TTTATACATATTAAAACCCAATAGATATATAGTAAATATCTATTGGGTTAGTGTTTT ATTCAGAGATCT

TAACTGTACATACTAATGGATTATGCTGTAATTCACTAACTAATTTAGGAATAGTTG TAAGTTTATATC

TAATAGATGGATTTTGTTTTTCTTCTTCCAATATACTAATCGATTCATGAATTCGAA TAATTTCTTCACG

ACTAATTGGTTTAACAAATATTGCAGGCTTACCAGTATTAATATTGATTCCCTCAAT AATATTCATTTC

ATCATGACTTGATAAGTAACCCACAATAATCTTAATATTTTTTAAATCTTTATACGT TAATCTTGTTTCT

AATAATGAATCATCTTTCATTACGCATAAACTTCCCTTCCAGTTTAAGTTTTATTTT ATATAATTATTAG

TTAAACTAGTATATAAAAAATTAAACTGAATTATAGAATAATTTATTTAAAAGAATA TAACGTACCTTT

CATATCATTATAATAACTATATTTAATCGATTTAAATTTATCCATACTATTGAAGAA GATAAATTCCGG

AGTATCTTTCTTAGGAGGATAGTTTACAATATCAATAATATGAGCGATAACTTGCAT ATCCATATCGGT

ATATTTAATATTAGATAGTTTTGTTTTTGATCGATTTACTGTAGTTTTTCTAGTCCT TTTATCAATGTAA

ATAGTAATTTCTTCGGGATTTTCAGTAAGTTCTTCATGAATTATATTGAGAAAATTT ACCGCTTCAAGA

TACGGTTCTAGCGATGTTTCCATTGTACTATTAAAGTTTTCTTCATTACTTTTAGAG TTGATCATATTTT

TAATATTTTTTAGTTTACCTATTGTTTTTAACATTATAATTTCCACCTTTAATTATT TATTTGTTGTTATC

ATATTAATAAAAAATGTATAGTCGATAAAATTAGACCCATTGTCTCTAATAATTTTT ACATCATCTTTA

AAATTAACATATTCTTTAATAAAATCGAGATTATGGGTTTTTCCTTTAATCGATTTT GAGTCAATATCGT

TAATTGCAAGATTTCTTATAACGTATGGACTATCTTTAGAATCATAATACAAGTTAT GGATTCTAAGAA

TAAATATACTATTATATAAATTTTCTTTTAAGAAAGATAAACTTTCAGTGAATCCTA ATTCATGAGTCT

TATCATTATATCCAGTAATATGACCAGTGCTGACATGTCCATTACTATGGATAATTT CAACTTTATTATT

AATTAATGATTCAATATTCGTTTCGTTTGTATACTTATCAAAAATAGTATGATTAGA CGCATTATAAAT

ATTAATATTCATATCGTCATCAATTGTATAAATATATTTTTTTGAGATAAGTTTATC GAGAATTAATTTT

AATGTATTTTTTCTTAATTTAAATAAACGCTCTTTTAGATAACATACTTTATCAATA TCCGGATACTTTT

CTTTTAGTGAATAATCTTTATTGATAGTATTAACGTCAATATATGATATGTATTCAA TATAATGAAGAT

TAATAATATCATTATCATTAAATGATGTTAATTTCTTTTTAATTGTAGTGATATTCA TTACTTCATAGTA

AATATCATTATTAATCTTTTCTTTTAAACTAATAATCAATATTTCCTCAGACTTATC ATTTGTAAATAAG

AAACCTAAATTGCTCATAGCACTTTCAATAAAAGAAATATTATTATCCATTTAGATT TACACCCTTTCT

AATCTATATATTCATTATAGTTAATGCATCTTTAAATTTTTGATCTTCATTCATATA TTTAATTAAGTAT

GGATGTTCTTTAAATTCATTATCATACTTAGTTAATTTATTATAGTATCTAATAATA AATTTTTTTGGTA

AGTTTTCTTGACTTCTCGATATTTTGAACCATAAATTAGCATTATCTAAGGGTACAG TGCTTAGTATAT

ATTCAATTGATTCTATTGGTAATTGGTATCTTGAAATAGTCATTATAATTGTGTGCA AGTCAAAATATT

CTATATATTTTAGTATTACGCTTAATTCTAATTTATGGTTTGAAACGATAATATAAT TCCAGAATAATTT

TGGAGCATATTTATCAAGAGAAATAATATTATCTATTGTTACATCATACTCAATATC GTATTGAGAGAA

TATTAATTCTGCAGTTATATTTTCCCAAATTTTAGTATTAATATCTATACTGTCTGC ATACTTAATAAAT AGATTAATATCGTACAGTAATAGTTTATAATTATATCCTATGGAAAAATCTATATTGTCA AGAATATTA

GGATTATTTCTCGATATATCTAATATTCTATTGCATATTTCAGGAATATTGTGATCA TATTTATATGAGT

TAAATTGAGATTCAATAAAAGAAGGGTAGTAATTTTCTTCACCAGTATCATACTTTT TATCAATATCTA

TAACTAATTTAATTATATCGATTTTTTCATTCTTTTTAGAAATAATAATTTTTCTTA TATCTTCGTTACTA

ATAGGCTCGGTATCAGTTCTAGACATAATATTCTAACAATCCTTTCTATTATTAAAA AATAAAATCTGA

GACTATAATTGATCATATAGTCTCAGAAATATTTTATATTAATCTTCTAAATTATTA TTTAATATATTCA

TAGACATATTAAAAATACTTCTTGAACGTTTACCGATACGATTTATTGTTTTTTCAG ATATATTTAAATA

ATCTTTAAATTTTATCGGAAAATACTTGAGGTACATAGAAATTTGTTCTGGATTATC AATAATATTGTT

ATCAATGATAGTTCGAACAACAGTATAAATTTGACCATTAAGTAATTCGTCAATAGT TGTTTGGATCGT

ATGCTTGAATAATTCATCCTTTCTTAAATGTTGATGATCTTTATACTCCATTTTCAT TCTAACTTTAATA

TAAGGATCGTTATAATCTTGATGATCATTAACTAGAGATTCAGGATGAAATATTTCA TTAAATAATTTA

ATATCGTCATTTTTTCCATATTTTATAATAATATTTGTAATTAATAATCTCGAAATT TCACCAATTTCAT

TATAAGGAATTTCTGATTCTTCAAATTTTAATGTATAATTAATTTCTTTTAAATACT CATTATAGTATCG

GTATTTATAATTAGATGTTAATGCAAGAGAAGTTACAAAGTTAAGATTATTTTGATA ACTTCCTACTAA

TCTAACTTCATTATAAAATACATTATCCTTTATAAGTTGATTAATGATTTTATAATA TCTTTGCATTAAT

ACATTAAACTTATCGGTACTACAATTTTTTGGTTTAGTAATTGATTTAATTAATGAT TGTTGGGTATTAA

TTAAATTTTCCATTTCGCTAAAGTCTGAAAGAACAAACTTGTCAGGATCAATATTCT TTAATAAGTTAT

ACGCATACATTAGAGTATTAACAATATCGTAATCACTACAAGAATAAATATGGTTAT TTCGCATAAAA

TTATACTTGAATTCATCACTAATTTCAGTAATTTGGTATGGAATACCGTTATTAAGA AATGAAGTTATA

ATGTGTTTAACTTCTTGAACTGGTGAACCGGAATTAAATAATTTTTCAATACATTTA ATTCCGTGATAA

CTGAATTCTAAGTCATCTATATCATTACAATAGTTCTTTTTAGGAACAATTGAATTC TTCGTAATATTCT

TATGAATATTACGAAATTCCCTATGAAGATCTTTAAAGTTCTTTTTGAATGTATCAT TATTACTAGTTTC

TTTTAAATTAGCATAAATCTTAATTGTATTATTCATTATTTATCAATCCTTTAATAT ATTTTTATTTTTCA

ATATTAACTTTAAATTCTATTCCTTGATCTACCATATCATAATCAATATCAGCAACT CGACCAACGCTG

ATAATATATTGCTTGTACAATTCAGTATCTTTAAGATTATGACCAAGATATGCAGTA TCATATCTGTCA

CTTTCAATCTCTCCTGGACTATATTGAACATTGGAGATCGGGTTATCATTTAGATCT TTTAATACGTTAT

ATTCTTTACGATCAGTATCAAAAAGCCTATTCATTGAACCTTCAAAAGCTACTTCAC CATCACTAAAAT

TTTGTACGGATGAACTTACTGTTAAGAAATATAGTGAGTCAGTTGTTCTAACTTTAT CATTAGGGTCAA

AATTAGATGGTTTTGGGTCATTATCAAACTTAACCCCTTTATTAGGAATAATATCCA TACGAACTAGAG

CTACTGTATAATCAGTGGCTTGTACTGGTCCGATTGTAAACACATAATTTTCAGGAG AATTACCGATAA

CTGTCATAATAATTTTATAATCATTATCATTAGTTACCCTATAGTCTCCTACCTCTG TAAGTTCATATTC

TTCTTCTTTTTTGGTTTTCATAAGAGGTTTAAGTTCTTGTATTTTTGATTGAACTGA ATCTTTGTTAACAT

GATTACTATCATTATTTAATACAAAATAAATAACTACTGATAACCCTATTAATAATA CTACAAATATTA

ATATTTTTTTCATTTGAAAGTTCCTCCGTTTTCTAGATTTTTATTGATTTTATATAT TACTTTTAAACCTT

TAGCAAATCTTTTAGATTTTACATCTTTCATACTAATTACATTACTTTTCTTAGCTA CTTTTTTAATTTTC

ATAATTGATCCATCCTTTATATTTTATTTAATCATTATTATAATATATTAATGAAAA TTATATTATTACG

CTAAAAAAAAAAAAATCCGTAATACTCATAAAAGAGTATTACGGGAATATTTATATT ATTTAAAATCT TTCACATATATGAAAACCATGATCAGTGGCTAATTTATAATCAAAGTTTAATCCTAGATT CATTAAATA

AAACTTATCAGCTTCTTCCTTACTGAATGTATTGATTAATGTTTCTAGTGACATATG ACATTCTTTATCA

TAATCATAAGTTTCGCAAGAAGCATCATGATATATCTCATCAAAGTAACCTTGATGA ATAAGACTTTC

AATATCATCACCGAAATTATTTGCGTCACCACTATAATATATTACTTTTTCATCAAC CTTAATAATATAT

CCATACGTCATAATGCTCGGAGAATGTCCAACAGATACTGCTTTTATTTGAACGTTA GAGTCAATATGA

TAAAATTCATATTCTTCAATAAATTGTATTTTATAATCTACGTCTGCATGAACATCA TTAATCTTTAATA

AATTAACGATATTTTCACCATATGATAAAAATAGATTAACTTTTATATTATGAATAT GTTTAAAGTATC

TAATAAATGTTGGTAAGGAACCTATACGGTCAGCGTGAGTATGAGTAATAATTACAT TAATGCTATCA

AAATTCTTTATCATACTATCCGTAAAATAATCATCAATTAATATATCAAACACCATA CTTCCACAATCA

ATAAGATAAAAATTGTTATTATTAATAAAGTATGCAGACGTATTTCCTAATTCTGTA TTAAATTCATTT

CCGGTTCCTATAAAATTTAGTAAATTATTATACATTTTATATACCGCCTTTATTTTT TTTTTTTATTATTT

TTTCTAAAAAAATATTGGATATTGTCATTTATTTGACAATATCCAATAAAATAAGGA AAGTGTAAACT

AGTTAGAATATTACACTTTTAGACGAAAGAGTAATATGGAGATAACAACTAGTCGTA CGGGATTAGAG

ATAGTTATATTTAGGCATAAGATTTACCTAAATATAATATATTATTATCCAAAATAT TAATTTTTTATTT

TTACAGTTTACGCATATAAATCTTCATTATAAGCGTATTGAATTCTTTATTGTATGA ATTAATATCCGTA

ATATTATAATTATGACCAATAAGATTATCATTGTTAATATTAGAATTATATACGCTA ATTGCATTATTA

TATAATGCTTCTAATTCATCATAATTTTCTAATAAACTATACTTGTAATGTATATAT ACAAAGTTACTTA

TAATCATATCGATAAATTTTGAATCGATATTTGCAAAATATATTTTACTAGAATTAG ATATAAGCGTTG

GTATTGTAAAATTACCATGATACATTTCAGCATTAAAATAATTCTTCTTACATATTT CATAAATAACAG

TATCGTCATTACTATTTAGATATTCATTATACGTCATATTAATAAAATTTGCAAGAT TGATTGGTTCTGT

TTTGATATTTGAATAGACGATATTATTATATGATTTATAATCGTGTAGCGTAGATCG TAATACATTTTC

AGTAATTACACTATTACTACGAGAAAAATTTTCTTTATATTGAAAGTACTTTTCAAT ATTAATTCTTAA

GCAATTATTAACTTCTTCTAGATTAGATCTAGATTCATTATTCGAAGTATCAATAAT ATCTTCCTTAATA

TAATTTCGCAGACTTTTCTCATCAGGATTATTATGTAATATATCTACTATAATAATC GCAGTTTTAATTA

GTATATCCGTAGATTTTTTATCCGATCTATTTCCAAAATTAATAATATTTCTTAAGA AATAAATTAATAT

CTTTGGATCATAGTTATACATATTATATATCATGCTGACAAATATATTGTTAATTCC AATTCTTCCATTA

AGAATATGTTCTATAAAATAATAATACTTATTTGTAGAATCTTCATTATATTTATTA TTAGCAATATAC

GCTGATTGGTTGGATACACGAATAAAGCTTGAATATAATGCAGAGATATAACTATTA TTAAAATAAAT

AGTTGGAACGATATTACAAAAGAAATCAGCTAATTCTTTAATATCTATAATATTTAG TATAGATTTTTT

ATAATACTTCATAAATTCTTTTGGCGTATATTGGAGATTATCAATCTTGATCTTTTC AGTGTCAAACATA

AGAGCGTGGGACTCATTTATAAATATATTAAAATCATATATATTTGAAGTGAATATA TCTTTTAGGAAA

CTATATTTATCTTTGATTAATGAATACATTGTATTTCTAATCATATTTTGAAAATAT ATAATTCGTAGAT

TATTACTTTTTTTAGTATTGTCAGAATCGACTAATGATTTAATTTCTTTATAATATT TTGATAGATTAGA

TTTGGAAAAAGTTTCGTTAAATTCTTTACAATCATCTAAAAATTTGTTATATACTTT ATCGACAAGATC

ACTATTACTGATTTCATGAGTATCATATTTATTTTTTATTTTATCGATAGAATTTTC GTCATAATAAATT

CTATCGATAAAACTACTAATTATCGGCATGTTGATGTATCACTTCTTTCCATTGATA TAGTGCATAATG

TCAATATGTAACAAAATGCTCTTACTCTGATCTCTACTGGCATTACAATAATCAAAT TCATGCTGATAA TGATCCAATAACATTAATGCATCGTTATATTGATTTTGGATGATGCTTGAAATATTATTA CTTAATTTAT

ATTCTAAATATTCAATAATATTTAGAACTTCATTGTCAATAGGATTAATTTTTTCAT AATTATTTAATAA

GTAATGATATACATTTTTATAAATTTCGACAGAATCATTACTTATTTGAATGTCATT ATTTATTGAAAA

ACAAAATAACGAATTAAAATCATTAGGATCAATTAATAGTTTTTCTAAAATAATCTT AGTCTTTTCACT

TTCTTTATATTCAATCCATCTTACAGGGATATATTCAGCTCTCTGCATGCTAATGAG AGATTTAAATAA

CTTAATTGAATTTTTCTTTTCTTGCAAACTATATTTACTAAAAATATAATTTATCAT ATTTTCTACAAAA

AGATTAATTCTACCAATAGTATGGTTTACTGTAGCCATGTTTGTTCCTTCAATAATA TGATCTTTACTGC

TAACATTAATAATAAACATTCTTTATCATCCTTCACTGTTTTATTTTATTCACATTA TTATAATATATAC

TTATCTTATTAGTAAAAAAAGAACTATCACATTTTATTATGTAATAGTTCTTCTATG GATTAATTGATG

AATTAATTTCTGTACTATTATTTATTCGGTTAATTTTATCTTCTAAAGATATCAACC TAATAACATTTTT

_{TTTTTTATTTGTCATATAAAATAAATCACTCTTTTATTCATAATTATTCTATTAT CATATGCACTTCTTTA}

TAAGATATATTTATAGAAACTGTATATTAATAACAGTTTCTATATTAATGATAGTTT AACTTTATCAAA

GATGTTTCTATGATTAAGAGAATTCTTAATAAGGTCATTAATAGTTATATTTATGTG GTAAGGTTTTAC

ATTATCTTCTGCATTATAAATCTGTAAATTTATATTGTATCCATTTACTATAAATTT ATAATATACCGAA

ACATATTCTCTTGTTACTGGTTGCTTAAAACGGTCAGACGTAAAAGTATAATTAAAT GTATAAGAATCA

ATATAACCATTATTAGTTGATAAATCACTGATATTATAAGTATATTCATCGATGTCT GATGGGTCAAGA

TCTGTATTATTTCTAATAAATTCATAGATCATACTTTTTAGGATTTCCGATAGATAT GTGATAGTTAATA

TTGAAGAACTAAATCTTTTACTATTAAATTTTTCTTTTATATTGTAAGTATTATCAT TATATTCAATATC

TTTTGATGGAATATTATAATTAGATGTAAACATTTCGTTAAATGTTTTTCGTTCTTC AGAAGTTAATTCA

TTTAATGTTTTAATTAATTCTTTGTCATTATATAATAAAAATGAATTAATTATATGG TACGTAATATTCC

CATTAACATGTAAAGGTTTACTTAAAAATCCTAGAGATTTTACCATTAGATAATTTC CTTTCTTTTTTTT

TTTAATATTAATTTTAGATATTATACATTTTAATTCTATCATAATATTTGATATTCT ACTTCTTTCCTTTA

TACTTATATGGATTCAAGAATCATTTTATCATATATTTTCATATGTTTCCCACAATC AAATAATAGATC

AATCATATTAATATTTTTGTTAAAAATTTTATCATTAATGAAAAAATCAATATCTAA TTCATTGCTATCT

TTATCCATACTAAATTTAATTTTGTCAGAAATAAATGTAAATTTAGTATAAGGATGA TAATTCTCCATA

AATTTATATTCGGGTATATCTTGAATTCTTATTAGGGCAGAGACTTCAAATTTTAAT ATTAATGCTAAA

AATTTCTTAAAGAAATTAGATTCTAGTATATTCCAGACGCCAAAAATATCATTCTCT CGATATTTACTA

AAACTAAATATACGCTCTAAGTTATCAATCATTTCCATATTATTTAGTTTTGTCAAT TTTTCTTCTAAGT

CATCATAAATCTCAAATATTTGTACAATATCATTTTGATTTGTTTCGAAAATATACA TAGATACTATTTC

CTCATACACGCTATTATCTATGTATGGAATAAATGAATTTTTAGCTGAATCTTTAAT CGGTTTTATATTT

TTCATGTATACCATTCCTTTCATTCTTTAATTTCAAGAATATTATGTGGGAAGATAT CAATTAAAGATA

CCTTCCCACATAATATATGTAACGATTGTTTAGTACAACATATCACTATATTTATTC ATAATATTCTTTG

TAAATATATAAAGGACTTGTTCAAATTCAATATCGGTCAAACATAATTTACCGTAGG CTTGACGATTAC

AAAATGATGAGATAGTTGATAATGAATTACCATGAAAAACCATTCTTTCAAGCACTC TGTTTTGATTGT

CATTAAGCTTATCATATTTTTCTTGGGAAGTGATCATTTTATGAGTCATACTTAATA GATCGCCTTCTAA

AGTATTAGGGAAAACATAATTACCTTCAGAATTTAAATAAAAATGGTTAAATCGATT TAATATTTCTTT

TTGATAATTTTCTTTTGTTTTATTCAACACTATTAAAACCCCCATAACCAATTAGAA TTATTTATATACT ATATATTTATTTATTAGTATATCAATTTATTTTGAGTAATATGGAAAAAATTATTTTAAA ATCCCTAAAT

AAACATATAAGTTTACTTAAGGATCATAGATATTTTTAATTCTTTATTTTATTAAAT ACTTTTTAATTTA

TTAATATCAATTAATTTCTTTTTCATACTTTCAGGTAATATTTCATCATGATACTTT AATATTAAAGGAA

TATTTAATTTATCAATATACGTATCAATAAATTCTAGTGATATATCTTGACATTTGC TAATAATATCCCA

ATTAACTTTATCTTGAAACTCAATAATAAAGTCTTCTGATAATGTCTGGTACCAACT AATAAAGTACCA

ATCTAAAGAATCTTTGAATCTACGAATAAAATCTTCTGATAATTTCTGTTGTGAACT AATATTATACCA

ATCTAATTCATCTTGGAACCTTTCAATAAATTCTTCTGATAATTCTCGATACCTACT GATGCTAAACCA

GTTTAATTTATCTTGAAACTTTTCAATGAATTCTTCTGATAACTCTTGATGTATGCT GATGCTAGACCAG

TTTAATTTATCTTGAAACTTTTCGATAAATTCTTCGGATAATTTCTGTTGTGAACTA ATATTATACCAAT

CTATTTTATCCTGAAACTTCTCAATGAATTCTTCTGATAATGTCTGATTCCTACTGA CATGATTCCTATT

AATGGTTATTTTTTCCATAAATAAGTATACCACCTTTTTGCTATATACTTTTTAATT TAATAATTTCTTTA

TGTTTATTAATAAATTCTCGTGATACATTTTGAATCGATTCAATATAATGCCAATTT ACTTTATTCTGAA

ACTTCTCAATAAACTTTTCCGATAATTTCTGTTCTCTACTGATATAACTCCAATTTA CTTTATCTTGAAA

TTTCTCGATGAATTCTTCTGATAGTTTTTGGTCAGACGATATATAGTCCCAATCTAC TTTATCTTGAAAC

TCTTCGATGAATTTTTCGGATAATCTCTGATATATACTAATATGCTTCCAATTAACT TTATCTTGAAATT

TTCTAATTAATTCTTCTGATAATTTCTGGCATAAACCAATATAATGCCAATCTACTT TATCCTGAAACTT

CTCAATGAATTCTTCGGATAATTTATAATATTCAGAGATACTACACCAATTAACTTT ATCCTGAAACTT

TTCAATAAACTGCTCAGATAATTTCTGATACGCACTAATATTGTACCAAACTACTTT ATCCTGATATTT

AGAAATAAAATTTTCTGATAAGTTCTTTTGATCCCTACTAATATTGTACCAAACTAC TTTATCTTGAAA

CTCTTCAATAAACTGCTCAGATAATGTCTGATACCAACTAATATTGTACCAATTAAC TTTATTCTGATA

TTTAGAAATAAAATTTTCTGATAAGTTCTTTTGATCCTTACTAATATAATACCAATC TACTTTATCCTGA

AACTTTTCAATGAATTCTTCGGATAATTTTTGATGTGAGCTAATAAATTTCCAATCT ACTTTATCCTGAA

ACTTTTCAATGAATTCTTCGGATAATTTTTTCTTCCAACTAATCTCAGTCCAATCTA CTTTTACTGAATC

ATCAACGATTATTTTATCCATAGATAATATTACATCCTTTCTTTTTTCACTATATAC TTTTTAATTTATCA

ATAGCAATCAATTTATCCATTGTTTCTTCAGATAGTGTATCTTCGTATCTATATATT AGATATTTAACGT

ATAATTTATGCATATATCTAATAATGAATTCTTCCGATAATTCTTGATGCATACTAA TAGCTTTCCAATT

AATTTTATCCTGAAACTCTTCAATAAAATTTTCAGACAATGTCTGATATTTGCTAAT TTCATTCCAATCT

ACCATATCCTGACAGTTACGAATAAAATCTTCTGATAAGTCTCGAACTGACGAAGAA GCATGCCGCCA

ATTAACATTTTCTGGAAATTTTAGAATAAGGTCATTAGATACATTTCTATTTAAGCA AAAATAATCCCA

ACATATCTTATCTTGAAATTTGGCAATAAATGATTCACTATTTAATTTCTGATGCAT ACTGATTTCATTC

CAATTAACTCTATCCTGAAACTCTTCAATGAATTCTTCTGATAGTTTTTGGTCAGAC GATATATATTGCC

AATTAACTTTATCTTGATATTCACGAATAAATTTTTCCGATAATTTTTGGTATTGAC TTATAATATTCCA

GTTTAATTTATCTTGATATTTAATGATAAACTTTTCAGGCAATTCTTCATTATATGC AATATATTCCCAG

TTAGGTTCAACAGTAAAATTATATTTTTCATTATACTTCATAGGAAACCCTCTTTCT TTTAAGCTATTAT

ATATTCTTCATTATAGTAATATTAGTCAGCTTATCTATAGTTTTCTGAGATAACGAG TTTTTATGAATTT

CAAGTACGAATTCAATATCCAAGCAATGAATATTCCTAAGAATAAAATCATCTGACA ATTTCTGGTAT

TGGATAATAAAATCCCAGTACACTTTATTTCCAAAATTTTCAATGAATTCTTCTGAT AATTTTTGATATT GGGAAATATTATACCAATTAACTCTATCTTGAAACTCAATAATAAAGTCTTCTGATAATG TCTGGTACC

AACTAATTTCATTCCAATCTACTATATTCTGACAATTACGAATAAGATCTTCTGATA GCTTTTGGTTTAT

ACTGATGTAGTACCAATTAACTCTATCCTGAAACTTAATAATAAATGAATCAGATAA TTCCTGAAATAT

ACTAATATATTTCCAATTAACCATGTCTTGATATTTATGGATAAGTTTTTCTGATAA TTTCTGTTTTATA

CTAATAAAGTCCCAATCTAATTTGTCTTTAAAAGTATCAATAAATTTTTCATTCAAC ATTATGTTCTTAG

ATATGTATGTCCAATCAATTTTATCATCATTTATGTTAATATCATTAGTTTTAATGT ACTCGTTAATATT

CATAAATTATAACCACCTTATTTTTCTTCTATATGTATAATATATAATTTTAATTTA TGTTAGATGTATA

AAAAAAAGGAAATGCGTATTTAATAAATGTATAATTCCTATATAATTATTATATTAT ATAAGAATTATA

CATTTAGTAGTTATATATGTCTTAATGCATCAATTTCCTCTAATCTATTTATGAATT CTTTAGATAATGA

TTCTGAATTATTATTTATTATTGAACTAATCGATACTTTATCAATATGATTATTAAT AAATTCTTCTGAT

AATTGTTGCTCTCCACTAATAACGTTCCAATTAACTTTATCTTGAAATTTATCAATA AAAGATTCCGAT

AATGTCTGATATCTACTAATATAGTACCAACTAAGTTTATCTTGAAATTTCTCAATG AATTCTTCTGAT

AATTGTTGATCTGTACTAATAACATCCCAGTCTACTTTATCCTGATATTCACGAATA AATTTTTCCGATA

ATATTTGGTATTGACTTATAATATCCCAGTTTAATTTATCTTGAAATTTCTCAATGA ATTCTTCTGATAA

TTTCTGTTGTGAACTAATAATGTACCAATCTATTTTATCTTGGAACCTTTCGATGAA TTCTTCTGATAAT

TTTCGATACCTGCTGATGCTAGACCAGTTTAATTTATCTTGGAACTTCTCAATGAAT TCCTCAGATAATT

CTTGATGTATACTGATGCTAGACCAGTTTAATTTATCTTGGAACTTCTCAATGAATT CCTCAGATAACT

TTTGATTTCTACTAATATCATACCAATCTAATTTATTTTTCAGATTATTAATAAAAT CTTTATCATCTAA

_{GTTTTTATTTTTCATAAGTATATCAATCCTTTATACTAATATTTAAACATGTCTT AATTTATTAATTTCTT}

TTAATTTATCTACAAATTCTTTAGATAATGATTTTGAATTGTATTGTAGTAATGCTT CAAGATTTAATTT

ATTTAGATATTTATGGATAAATGTCTTAGATAACTTTTGGTTTCTACTAATAGACTC CCAGTTTAATTTA

TCCTGAAACTTAATGATAAATTCTTCTGATAATACTTGACATGCACCAATATATTGC CAGTTAATCCTA

TTTTGGAACTTCTCAATGAATTCTTCTGATAATTGTTGCTCTTCACTAATAACGTCC CAATCAATTTTAT

CTTGAAATTTATCAATAAAAGTTTCAGATAATTTTTGGAACCGACTAATTAAGTACC AATTTACATTAC

TCTGAAACTCTTCAATAAATTCTTCTGATAACTTTTGATGTTCACAGATTAAAAGCC AATTTACATTAC

TCTGAAATTTACGAATAGATTCTTCAGATAATTTTTGAGATCGACTAACTTGACTCC AGATTAATTTAT

TTTGAAACTTACTAATAAATTCTCCTGACAGTTTTTGACATTGAGATATATAATACC AATCCAATTTAT

CTTGGAACTTCTCGATAAACTCTTCAGATAATTTTTGATATGTTACAATAAAATCCC AGTCAACAGTAT

TCTGAAACTTATCAATAAAAGTTTCAGATAATTTTTGATATATGCTGATATAAAACC AATTAACTTTAT

CTTGGAATTCTTCGATGAATTCTTCTGATAGTTTTTGGTATATACTGATATTTGACC ATACTACTTTATC

TTGGAATTTTCTAATAAAGTCTTCAGATAATGTACGTTTTTCACATAATAACCCCCA ATTAATCTTTTCG

GGGAATTCGCTTATAAACTCTTCGGTTAGGTTTTTATTCCACATAAAAGTATACCAT TCCTTCTCTATAA

AGATATTTAGATACTTTTTATTTTATTAATTTGAATTAGTTTATTTAACAATTGAGG TGATAATAATTCT

GAATTGTACTGTATTAGGTGTTCAATATTTAATTTATTTAAATGATTATAGATAAAC TTCTCAGATAAT

TTTTGATATCTGCTAATATAATCCCAATTAACTTTATCTTGGAACTTAATGATAAAG TTTTCTGATAGTT

TTTGATATTGACTTGTAGCATCCCAATCAAGCTTATTCTGAAAATCAGTGATGAATT CTTCCGATAATA

TTTGATATTGACTAACATCCTCCCAATCATTTATCATATCTTGAAACTTAATGATAA AGTTTTCTGACA ATTTATGATAAATTACGACTAAGTACCAATTAAGTTTATATCTAAATTTTTCGATGAATT CTTCTGATA

_{GTTTTTGGTATCCGCTAATAGTATGCCAATCAATATTGTCCTGAAGTTCTTCGAT GAATTCTTCGGATA}

ATTCTTGATATTCACTAATATTAATCCAATTAACTTTATCTTTAAATCTAGCAATAA AGTCTTCTGATAA

TTTCTGATATTGGCTTATATTATACCAATCTACATTGTTTTGAAATTCTTCAATAAA GTCTTCCGATAAT

TCTTGATATCGACTAATAATATCCCATTTTAAATTATTCTGGAATTTGCGAATAAAG TCTTCCGATAAT

TCTTGATATCGACTAATAATATCCCATTTTACATTATTCTGGAATTTGCGAATAAAG TCTTCTGATAATT

TCTGATATTCACTAATATTAGTCCAGTCAACTTTATCTTGAAATTCGATAATAAATT TCTTTGATAGTTT

TTGATGTTTAGAAATACTGTGCCAATTTACTTTATCTTGAAACTCACGGATAAATTT TTCCGATAATTTT

TGATATTTACTAACGTCTGTCCATCTAATAATATCTTGATATTCACGGATAAAATCT TCAGGCAACTTA

ACACATGATACCGTAGTATACCAATCATAACCAAACCTTTCAAGTGTTACGTGACTT ATATTATTATTG

ACTGTTTCCATAGTACTTAATTCCTCCTATAATATCATTTTTAATCTTATTAAGAAA TTAGACCAAGTTA

ATATCTAATTTTTTGAAGTATAAATTAATAAATTCCTCTAATAGTTTTATGAAAATA AAATATATTCTC

AGTATATTTATTATGTGAAAAATCAGCACATATTCATCATATCATTAATAATACGCT TTCTCTCTTTTTT

TGATACAATGTAATACGTGTTATCAATATAATTAAATTCTTTAATAAAATCTTCCGA TAATATTTGATA

TCGACTTATAATATCCCAGTTTACATTATCTTGAAACTCATGGATAAAATCTTCAGA TAATTTTTGGTA

CATACTAATATAATCCCAATCTACTTTATCCTGAAATTCTCTAATAGAGTCTTCTGA CAATCTTTGATAT

ATGCTAATATTTTCCCAGTCTACATTATCTTGGAATTCTTCAGATAATTTTTGATAC CTTGAAGATTGAT

ACAAATTTGTAATTTTATTATATTCAATATTAATATCATTGTTATATTTGATATCGC TATCATGATTATC

ATTATTATTTAGTGATAACACATGATTTTTATCTTTTATAACATTATCATATTTTGG AATATACAATATT

AAGGGATCATTATTACTATTATCATCTAGATTTTTTGAAATTTCAATATTAGCGGAA TTAGATTTAATTT

TATCAATATATACTTTATTTCTAAATTCTATAATAAACTTTTTGGATAGTTTTTGCG AATTGGATAATTT

TTGTGAAAATATAAGATGTTCCCAATATAATTCCGATTCATATTTTCTTATAAATTC TTCAGACAATCCT

CTGGTTCTATCAATCATGTTCCAATTTAAATTATATGGATTAAGTTCGACAATCTCT TCGACAGTATAA

TAACAATTAATATCCATAATAATCCCTCATTTCATTTATTATTTTAATATATGATGC ATTTATACATTAT

AATTATAATATATATTTATCCTATAAGTTATAAAAAAAAAAATCAAACGTGATATAT AATGATTATCA

CGTTTGATATGTAATTATTTTTTAAGAATGTTTAATAGTCTTAGAGAATATTCTAAA TATTTAGATTGAT

TTTTTACATTGTAAGTTATTAATAATAATAATGAAGAGAGAAGGAACAGATCTCCTG ATTTACAATAA

TCTTTTTGATATTTTCCATACATTACATTACATTTCAATAGCGTTAATAAGATCTAA TTCTGCAATAAGC

TGACTTACTCGGTGATCTGATAGATTTTTCCTATTTTGAATTTCTTGTTCTTTTGCT TCATCTAAAATATT

ATTTAATGCTAACATAATTCTATCTAATAGAACCATCGATTCCTTATAAACTTTTAC AGAATTTTCACG

_{ATTTTTAAGAATATTTATTAAATTACTGAGACTTAATTCATACTGTCTTATTTCT TCGCCATGATTATTG}

_{ATTTTTGTAAGTTCAAGTTTTGCAATAAATAACCGAATAATATCAATATTCCTAT CCCTATTATCCATTA}

ATAGAATTATATTTTTTAGATTTTCGCAAATACCATCAACTGATACCATTATATTTC ACCTTCTATTCTA

CTTTTAGTAAACATATTAAGTGCTTCTAATTCATTATTGATCATTTCCAAATTTACT TCTTGTAAATTCT

TTTCTTTCATTAATTTAATTTGTTCTTGATTTTCTTTTTCTTTTTCTACAGATTTAG TAATTACTTCTTCAA

TCTTAACAAGTAATGAATTTACTGTTGTATATACTTCATCTGAAAATATTGCACTAT TTTCATTTAAGTG

TCCAATAATTATATCATTTATGCTTGATAAACTTAATCTAATTTTATCATGTGTATG GATATTGTATTTT AATAGATTAGATACTTTTTTGTTTTTCATTAATGAATTAATAGTTCTTCTTAATCGATTA TTATAGTTTTT

ATCTTTAAAGTATTGAATATACTCGATATTTTTATTAATGAATTTAATAAAATCAAT AGCGTCCATATC

CGGAATATATTTTTCAGTTGAATAAATTATTGCATTATCATTATTATTTTTATATCT TAGTGAGTTTGAT

CTAGTTAAGTGCCTATTTATATATCTAAGATCATTTGTAGCTTGATCTATTTCACTG AAATTAACGGAA

TCATCTCTTACAATATCTTTATAGTCACGAAGTATTAAATATCCTGAACTAATAATA CCTTTAGTTAAA

TGATTATTTTTAATGCGCATATAAGTCTCAATATTATTTTTAATAATATTGAGGCAA CTTTGGATATTTA

ATGAATCAATATTATTTAAACTAATATATTCGATTTCATTAAACAATTTAGACAATT CTTTACTTCTAG

ATAAATTTTCTGAAAGTAAAAATTTATCTAAAAGATCATCATTCTTATTATTTTTTA TTTTAATAAATTT

AAACATTCGATCACCATCCAGTTAATTATTATAATTCTTTCTAATCTTTGTTATATA AATTTATTATCAT

TTCGAAAATTCAGATATTTCTCAATTCTCTGATCTTAACTAATTTACGCTTTATTTT ATTAGATATTAGT

TTATCATGTGATATCAATAGATCAATATCTAATTTCTTGAAGAATATATTAATGAAT TCTTCTGATAAA

TTTTCACAATATATAGATTTGCCCTTCCAGTTGATTGTACTATTATTTTCAATAGAT AAGTATTAATCTT

CAGTTAGATCAATAATATCTTCAAGATGTGAACCAAAAGTAGAATAGTCTATTAACC ATATTTCTTTTA

ATGGGTCTTCTTCAAGAAAGATTGCAATATCTTTTGCATGTTTCTTAATTTTATCCA CAATATAATTATA

CGTTCGATCAGCACCACTAGGATTCTTAATGGATCTTAGAAAAACGTCATCATAAGA TTCAGTTTCAAT

AATATGATATCCTTCATAAGTTTTATTTCCTTTTTGTAACGTCACCGATCTTAATAC ACTTTTTCGAGTT

TCTTTAATGCCAATTAGGTCAGCTAAATTAATTACTTCTTTTTTATTCAGATCAATT CCATTTTCTAGTA

CAAAAGGAACTGGTTGTAGGTTCTCGTATTCCTCATCATCAATATCACTTAGTGAAT TAATATATTCTA

AAGCATCATTATATGATTTAAATACCTTATGTTTATTCTTTTCCGTATTAGTAATTT TATATTTGATTGT

CATAGACCATCAATCCCTTCATTTAGTTAATTTTTATTTTTAAATTCTAGTTTAATA TTATTACTCTGAA

CCTTACGTAAATACGATAATATCGAATTCACCTTTACTTTCCATACATCATTCACAA CAGAAAGTATTT

GCTTCATCCGATAATATATCTGATTATTATTATCGATGGCAAGAATTATACTCATAT GCTGAGCCTGAA

TTACCTTATCAATCGTAATAATATCGTACAAGTTTCTTTCATTTCTACTTTTAATTA ATTCTTCGCCATC

ATTATACTTAATTGGTCTTATCTTCATAAGTTCACTAACAGATTTAATAATTTCAGA CGTATTTATACAT

TCCATATTATCATTCAAAATTTCTTTTAAATATTGAATATTATTATCTGTCTGCTTA ATATTATTTAATA

AGTATACTTCATATTCTGCGATAATAAATAAAATATCCTTATATTTTTCACGAACAG TACTAATCTCAC

GATTATTTCGAATATTATAGTCACTATCAATATTGGACATCATTCTCATAATAGTAT CAGATTTTTCTTC

AATATAATTAATATACGTTTCATTATATGCGTAACGTATAATATCCTTTGATACTTG GTTATTTATTGAC

TGAAGTTTATGCGATATTTCAAAGATCTCTATTTTACGATTAACTACGTCATAATAT ATTTCTTGAGCTT

CTTTCTTTTTATCCAGTGATAAGCTTGAATACGTAGGAACTTTATCATACATAGCAG GATGTATATACA

ATATATTATCTCCTTTCATTATTATTATTATTGTTGATTTATTAAATATATATTAAT AATATATATGCATT

TTTATAATAAAGTTTAATATTATTCCCTAATACAAGAATTTACATTTATCTTGTATT AGGGAACAAATT

TATTTATTTTGATCTATATTAATAAAATATAATACCCAAAAAGACCATATTAACCCA AAGATGATTATT

AAAAATCTAAAAATTAATGAATCTATAAGCAATCCTAATATAATTAATATTAGTGAC ATTATGGTTAA

AATCATTAATACTATTTCTTTATGATCTTTTAATAAGTTAAATATTTTTTTCATAAT AAAACCCCCATTA

TAATATAATAATTAAATGTATAAAAAAATTAAATCATAAAATTTAATTTATGTAACT TGTTAGGGGAG

AACGAGTTACGTCGTATCTCTTGCGTTATCAACAATATTTATAGTTGTTCATAAATA TTATGACTTTTGT ATTTTGCATTTTTGTTATTTCCAATAATTGTTATATAGTTTTGGTATATTAATCTATATA TTATTTCATCA

TTACAATAGAACCAACCTTATAGTAAAAATTATATATAAAGAATAAAAAATCTATAT AATTTACCTTC

GGTATAAGGATTGTTACATAGAAGGAAAGATCTACATATTTTTATTAAAAAGCATAT ATGGATTTATA

GTTAAGTCAGAACCAACCCTATAGTAAAAATTATATTAATAATTATATTTTATTATG AGTTTAATGCTT

CGTTGTAAGAATCTTTACATGCACGGATAAATTATAGTTAATTGTTATGTATAATAT ATCCAAGCATGT

AAGGTTTCTTAGATTATTTTTATTTTTTATTATTTTAATAACTAATAAAGATATTAA ACTTAATTTATTT

CGTTATATATAATATTAAAGTAATTATTTATCTATATGATTTACTTCTATAACTTTA ATTTCTAGTTCTG

AAACTTCTTCGTGTTTTCTGAATACTGATGCAGTATTTCTTGTAACGTATATTTTAT GTTTTCCGGGAAT

CCATTCAATATTGATTTTAAGATTATCCTGAATCATTTTAATGAGCGTTAGTCTACT AGCTTTATTTACT

AATTCGCCCCAAAGGTAATATTCATTATAACCATTATTCCTAAGAATGTCTAATTCT TTTTTTGATAATT

TGTATTTTGTTTCATAAGTTATTTCCATGATTTATTAATTATCCACCTTTATTTATT ATTTTTAAAGATCA

ATAATGTTATCTAGATGTAAAGATTCTTTATCTAATGAATTATTATCGATAATATAG TTAATTCTTGATT

TAACGATGACGTCAGTTATTCTCTTAATTTCTTTAATGCAGGCACTATATAATTCAT TCTTGTCTATTTT

TGTTATCTTTAAGGTAAGATCTTCAAGCTTTTCGTAATCAATTGGTTGTTCACGTCC ATACATAATCCA

ACTTGTATATCCACTACTTACTTTTTTTCTTTTCAGTATTTCAGTGTTATAGTAATT TGTGATGGTAGAA

AAATATTTTTGCCTTTTTCTTTTAATACTTTTAAAGTATATTTTGTTGTCTGAATGA ACGCAGAATTTTA

AGTTAAATGAATTGTTAATAAGAACTTCAAAATCTAAATCATCTAATACCATTTAAT AATTCATTCCTT

TCATTTATTTAATTGTTTTATGCTCCAAAGAATATCTGATTTTAAGTCTTCTAGGAA TTTTACCGTACTA

ATAATAGTGTTTTCGTGTAAGTAATCTTTTTCTAGTATCATTCTTTCTTTATATATT TCAATTAATTGGA

ATAATCTTTCTTTATGTTTAGAAAGATAAGCATAACCTAAGATTTCTGCTGAGAAGA CGATATATTCAT

CATTCAAATTATCAATTCTTTTTTGAGACAGATTATTATCATTTTTATAAGACGTCA TAATTTCAGAGAT

TAGATCATAATATAAGTTACTTAATACTTTTATTGTCTTTTCTATTAACCTATTAAA TTTTTCTGCTTTTT

CTTCTTGAATTAAAATAATCGTATCATTAATAGCATTATTATAGGAATATTCTTCAT TGCTGTAAAGAT

ATGTTTTCTTTTTATCTTCTAATTTCTTTTCTATTTCCTTAATAGTATTGATTTGTA TTTTTATACTATTAA

TTGAATCATCATCGCTGATTGGGATATTGTCCATCTTTTTAATAAGAGACGTATCCG TTTTTAAATAATT

ATCTTTAGTATCAATCGCTACCTTATTACCATCTAATTCTTTTATTATACCTTCTTT TGTAACGCCATTAT

GCATTACTTTTACACGTTCACCTATCTCAAACTTTTCCATCATTTTCACCCCACATC TATTTCTTCAATA

GGAACTGCAAATTGCCAATAACGCTCATCTGATGACTTTATTTGTTCTTTTGTTAAC TTAGTAGTAAAC

CCAGATGATATTTGAAAAGGAATAAGTTGTCTTTTTGCAAACATACCACTTACGCCT GTAGAAGGGTTT

ATCGCTAGATATAAATAATCATTAACTTTTTTAGAAACATTTTTATCCCATTTCAGT TCATTATTTTCAA

TAAATTGAACTTGTTCGTCTATTTCGAATTTCATAAATATGATTTCTTAAATTAATT ATTTTTTCACTAA

TAGTCTTATCAATATTAATAATATTATTTTTCTTCTTTTTAAAAAACATATTCACCA TTCCTTTAACTTAT

TCATTCTTTAATTTTTTGTTAATTGAATCTTTACTAATATTTCGAATAATTTCTAGT TCATCAGATAATA

TATCATCAATAGTATTATTCTTAGATATTTTAATATTTTTATCCATATCTTTATATA CTTCGAATATTTTA

GAGAAATCGTTATAGATAGTAATTAATATTTCTTTAATTTTTTCATACATAGATTTG GTAATTATTCCTT

CAGTCTCTTGACCAATATTAATAATAATATTGTAAATATTATTAATTGTATCAATAT ACTGGGAGAGTT

CTTCAGTGAATTCATTTTTTTGTTGATTTAATATTGACATATTATCAGACTTAATAA GTATTTTATCGAT TATATCTAAAAGTTTAACATGATAATTAGTTTTACCATTTACACCCATTACATAATCATA TAACGGTTT

AGATCTATTAATATTTTCGTCAATTTCATTATCTGATAATCTATCGTAGTTATACAA ACGATATCCACCT

_{TTTTTTAATATATTATACCTTTTTACATATGGATGAGATTTATTAATATTAATTT TGAAATCATATACTA}

TATTTTTAATACTAAATTTATCATACATAATCTGATACTCATAACTAATAGTAGAAC GTTCTCGGATGT

AGTATTTTTTATCCATAAAGATATTATCAAAGTATTCATAATATTCTTGGGGTGAAG GTAGTTTGTCTG

TAGTAATTTGAATTATTGATACCTTATGAATTGATTCAACTAAGGTATTAATAATTT GCTTTCTTAATTT

GATTAATTCATTATCGATAGTTATAACCGATTCTGTATCTGATAATTCATCAGTAAT CACATCTTCAGG

TTCTTCATTATTTATTTTTTTATGTGATTTTCTTTTAAAAAACATGTTCATCATTCC TTTTCTATAATATT

TATTTAATTTATTAATAACAATAAAGTTTTTTCTTTAGTAACTATCTTTTTAAAATA TTAGTTTATCATT

ACAGGAATAACTAATTTAATAGTTATTCCTGTAATAATTTTTCTTTTAATTTATATC TTCGTATATAATA

AGATACTGAATCATTTTTCATATGAACATTGGTTGAGATTTCAGAGATAGTTGCTTT TGGATTCTTTTTT

AGATATTCTAAGATACTATTGATTCTTGAATTAGTAGAATCATCATCACTATTTCGA ATACCTTTAATTT

TTCGATTATATTTAATATTATTCTTTTTAATATATGACTGAATTGTGTGATATTCTA CATTAAAATGTTT

TGCAATTTCTGTCATTGTTAAATTCGGATTTTCTTCAATAAATTTGGATAATCCTTC AATTTTTACTTTT

ATTTTCGGACCAATACCTTTTTTACTTACATATGGTAGATCATATTTTTTAATCTTT TCCCTTAATGTATT

TGGAACATAGTAAATTTTTTCAGATAATTCATTAACTGATAATTCGGGATTTTTCAT AATGATATTTCTT

AGATATTCTTTTTCCTGAATTTGATCTTTAGAAAGTTTTTTGATCATTATATATACC TTCTTTGTTATATA

_{ATTTTTCTACTTTTATTAATTCGTCTAATATAATTATTAATTGTAGATACATTTG CATTAAAATGTTTAG}

CAATCTTGCTTGCTGTAGCTTCAGGATATTTTATCATAAAATTAATAATTTCATTAT CATCAAACATTTT

ATCCACCCTTTTACTTTTATAGGGGATATTGTTTCTTTTAATTGTATTACCAATAAA TGACTTTGATACA

TAAAAGTGTTTTGCAATTTTATCTAATGTTAAGTCAGGATTATCGCTAATATATTTA GAAAGGTCGTTA

ATATTGATAATATCTTCATAAATAACAGTATCGTTATCATAATTATATTGCATATTA TATTCCTTAATAT

ATTTACGGATGGTTGGTGCAGAGTAACCAGTTCCTGATGCAATTTTCTTTATTGAAT GAGTAGGGTTAC

TATTAATATATTCTTTAATAATATTAGGATCTACTTTTTTCAAAACTTTATTCACAA CACTTTCATTTTA

TTTAGTATTCTTCTTTTCCTTAGCAAAGTATGCAATTAGTATGTATATTATCATAGA TATTAATGTTATT

ATATCTAAGACATATTCATTAATAGTTATTGCATTATGGTGTATTCCATATAAGAAT GTATATATTGTG

GTATACACATTATTGAATATAAGGATTATTAGAGGTATATACCTCATTTTATAACGA AGTTTATATAGG

GATACTTCATGACTACTATATAGTAATAATCCAATAAGAAGATTAGCCGTTAATGCT AATGTATATGTT

_{ATTTTTTCAGACAATACTTCATTAGTAGTAAATAAATTTATTGTAAGAAATATAA TCATAAAGAATATA}

AATACGCTTGTTATTAGTCTAGTTCGAATATCAATTTTTTCATTATTAATACACGAT ATATAGACTAAT

AAAAAGATTACAAGATTTGTTAGTAACATATAATAATAATCCTACTTTCCATATACT TATAAGAAGAA

TCCCCATTAATAAAGGATTCTTCTTATAATCTAAATTTATTTTACATATACTTTATA TGATTCAAGTAAT

TTATTTTTCTTTGATAGTTTAGTATTGATAAGTTTTCTGAAAAATAACTTTGTGTTG AAAGAGATTTGCG

TTAATTCTGTTTTATCTTCACCAAAATTAGTGCTTTCGTAAGATGCGGCTGATTTAA TTACACCCCTATT

AATAAGATTTTCTTCAGAATATGTAGATAATTTACCGTTATTACCAATCATAACTAC AAATTCAATTGA

TTCATCAATATTGCCGATAAAATGTTTTAAATTTTCAATAAAAATTCTTTTTTCATT AAATGTTCTAAGT

CTACGTTTTCTATCAATTTCAATAATAAATGCTTTCGGTTTCTTTTTGATATTATTA AATAGTTTAATAA TATCTTCTTTAATAAATTTTAGATTAGTATCACTGGTGATATAGTATTGTAAGTAATATT CTTCAGATTT

TAAATTATTTACTTTTTTGGTAATATCATAAAAAGTAGTAGTTTCAATTAATGGAAT AATATAGTTACT

TTTAATACTCGTGATAGCAGTATTAATACCAGTGACATCTTTATCGCCAATCACAAT TGTTTTTTTATTC

TTCTTAGCAAATTTTTCTAGATTATCAATCATTCTTGAGAAATCAGTTTTCTTAGTT TTTTTATTAGATCT

TAACAAACTTGCAACATTTAACATATAGTTTACCATCCTTTTTATTTTTTAGGTTTT TTATTTACAAACA

GTAGAATAATAATGGCAACGCCAATTCCAATAATTGCAGGAAGTAAATCTTTAAATA TATCCATGTCG

AATCACCTTTTATATTTTATTTTTTGTATACATATTCCGTATCATAATTTTCAATAA TAAGTTTAACAGT

TCCATGAGAAACTCCAAGAGATCTTGCAATCTTAGCAATTGAAAATTCAGGATGTTC CATTATAATATT

ATTAACAGATTCTATAATTTTTTCATTAGTTAAAGAATTATTAGACATATTAACTTG GTTATACGTTGC

GATACTAAATTTATATTCTTCAAATAGACTAATAATATATTCTTCGGAGAATCCTGT ATCTTCAGATAA

TCTTGCTGGAGTCATAATATCATTACTGTCTAATACAATTTTACTTAATCTTTTAAA GTCTGATAATCGT

GTATCAATCTTCATATCTGAAATGCTCATTTTTTGAAGTCTAATAGATGAAATATCT TTTCCTTCTTCTT

TCATAATTCTTCTAATAGTTGATTTTGCAATTGAAAATTCAACATTACATTTTTCAG CAATTTCTAATAT

TGTCATTTCAGGATTATTACGATAAGTATAAATAATATCTTTAGTCATCTTACTAAA TTTATCATTATGC

TCATAAGTTTCTCTTCTCTCTCTTCTTTGTCTTCTTCTACTTTCTGCACTTGTTAAA ACATTTTGACTCAT

TACCATGATAATCTTCCACCCTTTTTAATTAATTTAATAAATTGTATTAATATAAGA TTATAAAGTATAT

CTATGATAGTTTAAATTAAATATATTGTAATCGTTTATCACATGCCTGAATTACAAT AGCATCCCATAA

AGCATTATGTTTATCTTCATTTACTATGACATTAATATATTCACTAGCAAATTCTTC ACGATTAATATCC

GGATCAATATTTTTAGTTCTAAATACTGTAGAAATATCATAATAGTACATGTCAACA AATTCTGGAATT

AATGTAGCATCTTTTCCTTTATTAATTAGATCCACAAATAACATCCAATCGTATGCC ATTAAGTCACTA

ACAAATACTAGTTTTTCAGAACTATGCTTAGCATTATATGATAACCATTCGATAATT TTATCAGAAACT

TCATCTTTAGTTCCATATACTATAGTTGTCTTAGCATTATCCGATTTTGATGCTAAT GCGTCATGTTTGT

TAAAAAATCGAAGTTTAGGAATAACATTATCATTCACCCAAACACTTGATTTCGTTG TATCAAAATTAG

ATACTTCCGCATAAAATAGTCTACCGTACGTATCTACCATTCCAATACTAATTAGGT CGGCATCTTTTG

TTAAATTTGTAAATTCTGTATCAAAATATATCTTATTATCCATAATGTACCAACTTT CTTTAATTTGTCT

ATATATTTCTCAATATAATACTTGATAAGAAATTATTGAATTCTTTTATTAATCGAT CTAGCGCCTTATC

ATTAAGTAATGAATTTATATTTATAAATATGGATTGATTATCAATAAATTTATTGAT ATCTTTTATATCT

ATAACAATTAAGAACTTACCATTATCATCTTTATATAAAGAACTATTGATTGATTCT AATTTTTTATTTA

TATATAACATTTTACCATCAACAATAAATTTAGGGTTAGTATACACTAATTGAAACA TACCATTAGAAC

ATTTCGATTCAATAGGTAAATATTTATACATCTTATATTCATCTATAGATATAATAT CAATAATGCATG

TAAACAAATATCTTTTAATGATTTTTCACCCCTATAATTTATAATTTTGATACTATA AAATAAATATCAT

ATTTATAAATAATTATTATTCTAAAAAAATAAAAAATTCGATTAATGATATATGACA TATCATTAATCG

AATATAATCTATTTAAGTATAGATACTGTTACGTTAGATGTCCCACTAGAACCTATT TGCGATTTATCA

ATTAATAAATCAATTTTATTCCCAATAATTGCGCTTCCCGTATCACATGCTTTAGCG ATAAATGAATTA

CCATTAGGATATGTAATTCTTAAAATACTGTTCATTGGAATTACTGATGTATCTACA GCTACAATACGA

TGACCTTCTGGAGAATAAATAGTGTTACTCACTTTAGTTCCATTAGCAGTAATTCCT GTGCTTGGAGTA

TAATCATCCCCAACCGCATATACTGTCATACGAAAAGAACCAATTTTTCTGTATGAA GAATTTTCTTTA GTTGAAACATTCCGTACAGTTTTTTTATTTTTTACTTTATGACCTTTGTTTAATTTTAAT TTCTTGATAAG

TTTAATATTATCATTCTTAATATTTTTAATAATTGTATCTTTATCTTTAATTTTCTT TGTAAGTTCTTTTAT

ATCAGTAGACATTTTATTACTTTTATTAACAATATTTTCATTTTGTTCTTCTAGATT ATTATTGATTTTAT

TCTGTTTTAATATTAATTTTTCCTGACTTTGGATCATATGGTTTAGATTAGATTGAT GAATCGTTTGAAA

TGCTGTTAACGATAGTAGTAGAATTACGATAATTGATACGCATGTAGTTTTAATATT CATTCGATTCAA

TTTCTTTTTCTTATGCATAGATTCCTCCATTTCTATTATAACATTAATACTATTTGC TATAGTAAAATTAT

ATATCAAAAAACCGTAGTATATTATTATTGTTTTAATATACTACGGTTTCTTATTTT ATTTTATATTATT

TTTTAAACAATATTACTAAGAATTTTTGGCGTTTTTTCCACAAAATAAATTTCATCT GAATTGATCTCAA

TGATATTGGCAATTAGTTTTTTAATAAATCCAACAATATTACTGATATGGATAATTT TATTTTCGTTAAG

AATTGAGAAGTTATCTAGTAATCCATTAACTTTTAGATTGATATATGAATATGATTC TTTATCAATATA

AAATTCAATAAGGTCGGAATCGATAATCCTAACATTAACTATATTATACAAATTTGC TTTGTTTTTACT

ATTAATGTCACTAATAAGTTTATCATAATCATCTTTATCCGGAGTATGAAAATAATA TGGATTTAAAAG

ATTAATAAAATTGATCTGATATTCTTTTCCTAAAATATTAAAAACTAATCCATTTTT TTCTGAAAATTTA

GTTGTAAGAACTTTATCTATAATCACTTTCTGTTCCATTTAAACCACACTCCTATAC CATATTATTAGTA

TTAATAACTTATTGTATTAAGTTATTATAAAATACCCAATACGTTAAATAATAAACG TATTGGGAGTAT

TAATACTAATAATTATTGAATTCTATCTTTAATTACAACTATTGTTTTATGGAAATT ACTAACAAATTTA

ATATTTGTGTCATAATATTTATTTCTAATATTATTAGGGATGTGACCAATAATATCA CTATAAATAGTA

TCAATAGTCTTATCGATATTTTCAATATCCGTATATACATAATGAGATAAGTTATTT ACAATAATTTTTC

CAATATCAATATATTCATTTTCAAACATATTAGTATATTCTTCAGGACGTAGTAAAT TCCTAAATAGAT

TTTCAATATTATTAATAATTACATCAATATTTTCATCATTAATAATATCATCGATAT CATTATTAATAAT

AATATCAACAATTTCATCTACATAATAATTAACATTGTCTTTTTGATTTTCAGTAAT ACCGATTAATCCG

TCAACTTGCTCTACTTTACCTGGATTATCATCATAGATATTACTATCCATTGATGTT GAAACGTTATCCA

TTTCATTAACGCTTGAATCTTCTTTATTCCTACCACTAAATAACTTATTAAATAATT TCTTAAACATACA

AATCTCTCCTTTTATACTATATTTTACTATTATTATAATATATAAATAAAAAAATGA TTAAATTAGTATA

TCTCCAATCAATTTATATTTTGATTAGAGATATACTAATTATTTTTAACTTATATAA TCATCGATATTTA

TTTCTTTAAGTTTAATCGACATATCATGAAATGCTTTATATTGATAGGTAATTTTTT GAAGTTATCTCCA

AATTTTCCCCCAATCCAAACCGTACGTGAGACTTTCATCTCATACGGCTTTCCATCT ACTAGGAATCTA

AACCTAATCTGTTATGTATCTTTCTTTTTAGTAGACTAAGGACTTTCCCTAATTTAT ATTTCTATAAATA

TTATCGGTATCTTATCCTCGCTTTCAATCCAAATAAAATTTCAGTTATAGTCCAGAT TAGACTTTCCGA

GAAATAAGTATTATATTAATACTTTTGGATCTTCCCATGTTTCTATAGACTTAGGTT TATTATATAACTT

AGGACTTTTCTAGACCATATATCTTACTTCTTAACATGATAAGCTAATAAGGTTATT ATCAATGATTAA

TAACTATTAGAAGATATATTTATACATTACTGTATAGGATTAAGTCATTATAGAAAA TTCGTTAAATCT

ATCCATATTATACTACCCAAACCAAGATATCTTATCCTTTTTAATTAAAAGGACAAT CTTCTTGACTTC

ATCCAGCTTCACACATAGTAATTACTTGCTATGCATGTGGAATATTATTTTCAGGAA AATCTTAGAATC

TTTGTTATCTAAGTCCTTGATCAGTCTATAAATTAAATTATATAAAAATATAATTCC TACAATCCCTCAT

ATTAAAATAATGATTTCTGTAGAACATGTCACACCATTGATAATCCAGTTAATGCAT TCCCAATACCAT

TCGCAATTAGCCCAACATTCTTAATTCCCATTTGATAGTATAGTTCGCCTGCACATT TATTACAGATAT GTTCAGACTTACAGTATAATGGACTACGCATTTCAACATTCTTATTAATAAATTTACCTT TATTTTCTTC

GGTAATTTGCGTTAATTTATCACCGTCTTTTACATAACGAGTAATAAATAAATTAAT ATTATTATTTGT

AAGTGTAATATTTAAATATTTTTTAGATTTACAATCACTTCCATGATCGCCAAGAAT TATTGACTGAAA

TGCAGCGGCAAGTTTTTTCGCTTCATATCCACCATCTTGAGTACCAATAGCACGACT TGCACTAGCACT

TGTAATAATTTCTGCATATTGATATAGTTCGTCAGGAGGAATACCATCGTCTAGTGA AGCCATACTAAC

TCGAACATCATTTGGGTCCGCATAACTTTTAGTTACACCTCTAGCTACCGCTGTTTG TTTAAAGTTATTA

TTAAAACTTCCACGGCTTCCACTATCATAAATATCCATATCGGAAGCATCTTTAAGA ATATCATGGGAT

AATGTTAATAATTCTTTTTCTATTTTAGATACAGTAACAATATCCCCAGAATCAATT GCCTTTTTATGCT

TAACAATCAGTTCTTCTTTACGAGATTTTACTTGAGGAGGAGTCATCATTAAAGTTG TACTAAGTGATG

TTGCAATGAATTTAGTTATACCAAAGCCCAGCCATTGCATCTTATCAATATAATTAC TAAAATCAGCTA

CAGTAATTTTATCTTCTAATAAGAGAGTACTTAATTGTTTATCTAACTTACTAATAG CCCCACCATCCA

TTGGATGATTAATATATCCAATATATCTTCCTAATTTTGCATCAATAATTAATAGGT TAAAGATATATC

GACCTACTGTAGTAGTAATTTTATCTTTATTAAAATGAATATTTGATTCTAATTCAA AATAATCACTTG

GGTCAAACTTTGCATCTTCATTTTTGGTATATGCAAATAATTCTTGTAATTTTTCCA TAGTGATATCATT

CTCTGAAAGATTAAGAATCTCAATCTTTCTAGCATCACTAATCTTTTTACCTTTATA TGCTTTTTGCAAC

TATATTCACATCCTTTATAAATTATATCCTTTAATATAAATAAATGTTCTATTAGAT AATAAAATTGTTA

GGATCATAGAAAAAAAAAAATATAACCTAGATATCTAGGTTATATTTCTTAATATAA TCTGACCATAA

AGAATTAATACTTTCCTTATCTTGAACGCTTATTATGTCTTTTAATTCAATTTTATT ATTTTCTTCAAAGT

ATATATACGATAATATACTGGAGATTGCATCATAACCTTGTTCATCCGTATTAATAT AAACGTTATCAT

CATTACCATAATCCATAAATGTATTATATGATCTTTTTGATTTTATTTGTACTGGTT GATGATTAATTAC

TACGTCTGTTCCATTCCTATCTAAATATGCAGAACATTCCATCCAAAATTTAATTTT CTTTTTATTAAAT

ATATTCTGAACTTTTCCTAGAATTCCCATTACTGCAATTTCTGCATAGTGACCTTCA TTAAGCATTGGTG

GCAGTTTATCAATACATTTTCCGTTGAATCCTTCTTTTCTTGCTTGGTTCTTATAAT AGTTCAATTCATTT

AAATTAATATACATCGTAATATTCCCCCACTAATCGTATTATTTATAGTATTATTAT TTTTTCACAATTC

TTACATTTGGTTCGATAAATTTAATAAAACAAAATTTCATTGATAGCTTTATAATAG TATATGTAGTTG

CAATCATAAATACAATATTAATGAATATATTATTGTCATAGTTCCACAATACTACGT TTGAAGCAATAA

TTAATAGAATGGTCAGTATTACCGTTATCATAATTGAGATAAAGATCTTGTTTACTA TACGATTATTCA

TATCATTTCCCTACCTTACTTTTACTTTTTATAAACATGTCTACTTTATTACGAGAA TCCAAGTATTCAG

AGAACTGATCGATGAAAAGATTTATTGATATGTTATATGTTAAGTATGAGAATGAAA TCGATACTAAT

AAGTCTAGGTAAATATTATTATTTCTAAAACATACTTCATTAATAAAAAGAAACCAT AATGATGACGT

AATAATAATATTAAATATTACTTTGGTGATAAGATTTCTAAATAATTTATCACTAGA ATAGATACTTAG

TATACTTTCCTCTCTCTCAAAATTAAATATAGCCATTACAGTTCTTAACATATTTTT TCTACTTTTAATTT

CGATATTCTTAATTAAAAAGTTGCATAAGAATAACACTGCTTTATTTATGTACATTA TATAATCAACCC

TTCTTTTTTTTATTTAATCATTATTATAATATATCATTAAAACTTGTATTATTACAT TTTTTATAAATTAG

AGGGATATGACAAGTTATATGTCATATCCCTCTAATAAATATAATTTATGCTACGTA AATAATATATTC

CATTTCAATATTTGTAGATAATCCACTTAATGAGATAGAATCAAAAGTCAATCTTGA TCCACAACTAAT

GTTTTCATAAGAGTTTTTAGTTTCATTGTATCTACCTAACCATAAACATAATTCATT GATCATTCCACCA CGACATTCACTAGGGTCGATAGTTAATGATAGACTATATGAAACTTCTCCAGTAAATGTA TTAATATTC

CAACCTTTAGAATTACCAAAAGGTTTTGAATTTGTAGCACCATTAAATCGTTTACCA TAATATTTTACA

GTACCATCCGGATCAGCTTGTGGTAAATAATATTTCATTTTTTGTTCATCAGTAAGC TCTTTTACAATAG

AGGGATTATCTTGAGTTTCAGTATCATTATCCTTATCAGGGTCTACTGTAATAAAAG GAAATTTTTGAG

CTAATCCATTATCATTAAATTTTGGAGCAACTGGAGTGAATGGACTAGCATTAATAT CCGCCCCTCCTT

CTCCTACTGAGAATAGACAGATTGATCTTGCAGGATCATAGACTTCGTTGTATGTTG ATGGATGTTTTT

CTTTTAATAATGCTTCCATTACAAATACACGAGTTCTTTGTAAAATTAAATTATCTT GAATATTGATTAC

TTGTTTTGTATCTGCATTACGGAAAATAACTTTTCCTCGAATTCCTTTATCTGAATC TGCAGTACCAATA

TTATCTTCAAAAATTTCTTGAATGTTATTATCTTTAGACATAATGTGGATTACACTT CCTATTCATTTAT

TTTATAGATATCGATCTTAATCATTTGATTTAATAAATAATTTATCACTAAACGTTA TATTATCATCAAG

ACGTTTTGTTAAGTTTAAACTATGAGAATCAATTATAGAAATATAATCCCTAAATAG TATTCCACCTAT

TTTAGTGACATCCATGGTATCAAACAATCTTATACTGTTATCCATTTTACTATCAAA CTTATAAATAGA

ACTACTATAAACTGTATCGATAGTATAGGATTTAAATACTTTTATGAGGATATAAAT ATATGATTTTAC

ATAATCAGATAGACCAATCGTATTATTTTGAGTTAAGAAATCATATTCCCCTAGATT TAAATGATTATC

AATACTTTCAACAAGTTCAAATATTCTTTCACGATATATATCATCTTTACTTAATGA ATCAATATCGTAT

ATATTAATATCTACTTCTGTATAGAAATATAAGTTTGGATCATTATCTTTTAAGTAA TCTGTAAACGTA

TTATATTTTGAGAAAATATCCATATTTAAATCATTTGTAAATTTTTCATTCCATAAT TTATTAAACAAAC

TATATAGTTTATAATCATTTGTATTAATAATTGTTTCTTCTAAGTCTTCCCTTAGTT TTTCATTATATCGG

TATATTTTTGCGAAGTCATTCATAGTATATCTTCTTTTATTATTGACTATTTCATCA TATGAACCAAAAA

CATCTATAAATACCGATAAATTCTTATAGTTTATTAGCTGTTTTCGATAAATATATT CATTGACTGAAA

TAGCTTCATCAATAGCTGAAGGAATCATATCAATAACTTTTCTAAAGTTCTCAATAG TTTTATTTCGAT

TATATATATCAAAAACGGTACTTAACCTGTTAATACCAAGCTTATTTATAAAGTCTC GCATTTCAGACA

TTATTACCACGTTGTCCATACCAAACTGGAATATCTTATCAGTACTAATATATTTAA TATCTACCTGAT

AATTAACAAATCTTGATAGTAATTGTTTCAATAGACTATATTCCGATATTATAGACA TTGATATTTTTCT

_{ATTTTTATCAAGAAGAATATTCATTAAGTATTCTAATCCATCATAAATATTACCA TTCTTAATGTGATTT}

TCTAATTTCTTAGAACCGTTAATACTTTGGATGTATTCTGAAGTGAACTGCATTTGG TTTTGGTAAACT

ATTGAAGAATTATACATTGCTACAATACTATCAAAATCTTGGTCTATATCTAAGTCA AATCCTTTCAAC

TTAAATCGATTTAGATAACCCATAATATTTTCCCATTCTCGTACTCTGAATTTTCGT TTATTCCAGAAAA

GATATTTTCTTAATGAAATAATAATATCATTTACATTTTTATCAATATCATATCCGT AGGTATGTTCTAA

GAATGGAATTTTTCTAATTTTATCAGACCAATTCATTCTTTTTAATACCAGTGTTAT TAATGCAACAATA

GCATCAAATATATGAATTTCACTATCAGAGATATTGCGGTTATTAAATTTAAAGTCA ATATTCTCAAGA

TTAACTACTTTTGAAGCTTCTTGATAGGTAATATTATTATCACTAGCATATTTATTG ATTATTGCTCTAT

TTTTAATTTCTAGGTCATTTAATAATCCATAAAAGTATGATAATTGTTTCGAATTAT TAATCAGATCAA

GAACAATATCGACTGAAATATACTTTGTATTTATAATATTGAATGATTGTTCTAGTA TATTTTTCTTTTC

AGCTCGCCAATAGGGATCACCTTCAGTAATTGCGTCATAATCTACCCTAGGATGAAG CGAAAAATTTA

ATTCTTCATCAATAGGAACTTTATAGAATTCTAGTGAGTCATCACCGCCTAGATTAT TTTTCTTAGCAA

GCATATACCTATTTATCTGTACATTATCAAAAGAGAAAAGATTCTTTATGACATTGA ATACATCATTAT CTCCCTTGTTACGAATCATTTCATTTATTAATCGATAAATTCTTCGTTGATAATTTACTG GAACAGAATC

AAAATAATCTAATCCCCATGATATAAATCCATTTTTTAATTTTTTTCTATCATAAGT ATCAATATTAAAG

TATCCTTCCATAGTCTTATTAATATAACGCATTATAGTCATAAATATTAGATATTCT CGATATACTTCAC

GATTATATGTTTGATTACTAAATGCTTCAGTAAACGTAACATTTAGGAAATAATTAA TCGATTCATAGT

AAGCTTCATTAAATAAACTTTTATGCCATTTATCTAATGTATTACTAGTTTCTTTAA GTATATAGAAATC

TTTTGCTCTTCTTGCTGAAGCATAATCAATATTATATCGATTAAATAAATCTTTATA ATAAGGGTTTGAT

TCATTATATCCTTTAATGATATTTGATTTTTCTGATTCTGAAAGTTCCGAATCACTA TCATATATAGCAC

TTAAATATCTACTAGAATTTAATAGTGATGAAGGAGTTTCATTTGCTTCTGCCAATT GAGTATCCTTAA

TTACTAGTCCACGAGCATAATTTATAACATCTTTTATTTCATTAATATCCGAGTCTT TAAATGCATTATA

AAAATAATATGGTGTATATTTTCTTAACATCTCTTCTTTAAATTCATTGACCAATTA AAAACGCCACCA

TTCTATTATTATTTTTATATTATAAAGAGTTGTTCATAAGTTATAATATCTTTTTAG TTTTGATATAGAA

ACAATATACTATATATTAAAATAAAGTTAGGGTGATTTATATATGAATATTAAAAAA ATAAATAAGAA

TAAAACAGTAAGTAATATTGTATCTATCAGTAAAGATGGAAATATAATTCTTAAGGA TAAGAATTATA

CAAGTGATAATTTTTTAGACTCATTCTATATAAAGTCACTGGATAGTAAATCTATGA ATAAATTTATAA

AAAATATAGAATCATTAATTCGAACATCATTAGAGTATTCTAGATATATTGGGTATT TATCTACAGTTC

AAAATATCAATACAGATGCAATTATGGCAAATATTAATTCTGATGATGCCAGTCTAG AGTTTCATCATT

ATCCATTTACTCTTTATGATATTGTAGAAATTGTTATAAATAAAAATATTGCATTAC AAGAAAATTTTA

CATCAATATCTATAGCTAGGGAAGTTTTAAAATTACATTATGATAATATGATAGGAT TATCTAGAGTCA

GTAGAACGGTACATCAATTAGCTCATGCCGGCGAAATTTTTATTCCATTAGATAGTA TATTTGGAAGG

GTTAATGATTTCGTTAATGATTTTTATGAATATATTTATCAAGAACACATTATTACG TATAATAAGATT

ATTGAAATTTATAATAATAAGAATTATGATAATGATATAACAAAATAATTTTTAGTT ATATATTATAAT

TAAAATAATAACTATTATAGGTGGCGATTATATGAAAAAAGGAATAGACGATTATAT TAATAAATATA

TAAGTGATGATCCAGAGACTCAAAAAGAAATAGATCTCATTGTAAGTAAAATAAATG ATTTTAATAAT

AATTGTATTGAATTGATGAATGATGAAAATATGATCTGTGAAGAAAATATTATTAAT GGTACCATTAA

TGAAGTTAAAGACATTCTATTAACGTTATCAAATACATTTACATCTGTTTATATGGC GAACAGAGTTAT

TGAAAATATTGAATTATTTATAAATGGTGAAAATGACGAAGAGCTTCATGAATATAT TTATATAATGC

AAGATTCAATTGAAGATTTTGATGATATTCCTTTATATGACAAAACGTTATTGTCTG AAGCGATTAATA

CCATTCAGCGAGCAGAATTTCTAAATATGATACTCAAAGAAATACATATCTCAATAT ATTTAGAAAAA

ACACTGAAATTATTAAACGATATTATGGATTATAATAGTGATAATTTGCCTTATGAT ATGTCTATAGAA

ATTAATGCATTACTGATGAGTTCTGAGTATACATTATCAGTTATATTAAGTCAATTT AATCATATTATA

ACTAAGTCATATACTAAATATCTAAAGATCGTTGACATTATCTAATTTTAAACCTAA TACCATAATTTT

ATGGTATTAGGTTAATTTTTTTTTTTATTTTTTAAGGTTTAAACTACCTAGCACATT TGTTTCTTTATTTC

TAATTCTTTCATCAACAGTATTTAATAATTTTAAATTACCATAAATTACTACTGCAT AGGTTTTATTTTC

TTCCGGATTTTTTGTTTTAACAATTAATTTATCAAAATCAACAGAATATTCATCTTC TGTAAGCATTCTG

TTATTTGCAAATATTTTTACTTCAATACATTTATCCATATTTCCATTATTTTTTTCA ATTTCTTTAGCAAC

ACGAATTAGTCCTGAAGACATTATTGATTTAATATCCAATTCATCATATGCTACATT AAAGTCAGGAAT

AAATTCTGAGAAATATAAGATTTGCTTTTCATTAAGAGTTGGAGGTATTAAATCTTT TTGAGTTATAAT ATTAAACTTAAATGTATCACTATTATCTATTTCTGGAATATCTTTTATAATATTTTCGTT TCGCATTTCT

AAAATAAATGATCCCGGCATCCATAATTCTGCAGTCATTGCATATCGCACTTCAGAA TAAGAATTGAT

TAGATTATTCATTATTTTTTGAGAATTTGCTAATTCTGGATATCTTAACATGATATT TGCAGGATACTCG

CACATATAGGTAGGATTATTTGTAGACATATTTATTTTTTCTATAATTGGGTTTAGT GAATGAGATAAT

AAATATTCACGTAATTTATCTTTATCTTCTTCATTATCAAAATCTAAACCTAATACA TTACATATATTCA

ATATAAATGATAATGGTATTTCATAAGGTATTCTAATATCATTAAGGTAATTTACTC CGTTATTCTCAA

AATTCTGATTTAAGAAATTTAAGTTATTCCAAGCAGAAAGTTCACTAGGGAGTTTCA TGTATATATCAA

AACGTAATTTTATCCGATTAGGAATATAAAAAATACGAATATCATTTTCATGATCTT CAAATACCATTT

TGTATTCTTTGTGTTTATTACGATTTTTTATATAATATTGATGAGTAGACCAAAAAG GTAATATATCAA

TAAATGTATCACCTAACTCAAATTTAGGGGAGATTCCAATGTATGGTTTAGGCATAT CAGTAAATAAC

CCTTTACCATTACTAAAATTAGTCGAATTTAATGATTCACCGATATATACCTTTTTA AAATATTTAGGT

GGAAATTTGCTTATAAAATAGTTTGATATGAATGATGATACGCCACTAATAACATTA TGTATAGATGG

ACTAGCAGTACATAATGCTACACTATTATTATATTCAGATCTTGCAGGATCTAACAT AAGAGAATCAC

GCCTTTCTATATAATGTTGTTCACAAAACAAAAAACCCCTATTACTATAGTTATATA GTAATAGGGTAA

AAGATCAGAGATTGTGGGATCTCTAAAAGTGTGGAGTACAGAAAGCATATACAATAG GTTAAAAAAT

AAAAGGTTAAAAAAATCCTATCGTATAATATATTATTTAGAAAATTACGCTTAAAAA AATAATATTAT

CTCTAGGTACTGATGCTCGAATTGTATACATGTTTGAAATGATGAATTTATCAAAGT CGAAATCTTCTC

CAACAATTTCTTCAAACTCTTCATTTCCTCTAATAAATTTATTAATGATAATAGTAG TTTTATTAATAAT

TTCGTTAGTCAAGATAACCTGTACTTTTTCTACATATTTATTCATGTTTTTATCATC ATTTTGATTTTTAA

CTTCAGGAAAATTTTCATTTTCCGGTTTATTTAGTTTTAATACAAATTCAGGATTAT CCTTATTAATAAA

GATTCTTGAATTATTATCTTTAAAATCAACTTTTTCTGATTCATCAATAATTTTTCT TAATTCATTAACT

AAATTTTCTTTACCGATAAAACTAATAATGTTATTTCGGATAGCAATTTCTTTTCTG AGTTTAATCAGTT

TTTCATCATCAATCATCTCATTTAGTCTTTTCTCATTTTCATTATAAATCATCTTGT ATTTTCTTCCCTTC

TAATTCCTTTTCAGGATTATATGTTAATTCACTATTAATTTCATTATTTTTAATTTT CATTGCAAGATCTA

ATATGTCATCATCTAGTGTTTTTTTAAGTTCTTTACTTATGCGTATATTTTTTGAAT TTGGGTTTTCTTTA

AATCTTATTATTAGATTTGTTTCTGGATGAGTATTATAACGTTTTTCAGATATTAAC CGATATACTTGAT

TATCATCTTTCCATAGTATTTTATTTAATAAGTCCATTAATGTTTTTTGATAATTAT CGATATCTGGTTTT

TTAATTCTTTTTTCCTGATTTGTCAACATTAGATATATTTTATAAAGGCTATTTCCA AACTTTGTTGGAA

TATTACTAAATATGGATTCTAATTCTATTGGACCTTCAAAAGCGTTTTCATTAAAAG GTATTTTATTCTT

ATGAACTGAATTATATTCGTTTATAGATTTAATTAATATTTTTCGAAATTCATTTTT ATACCCACCTAAT

GGATCGTATGTGCTACCAATGATATTAAATCTATGTCGTTGATACGGTAATATTTCC CTATCAATATTA

ATATGTATTTCATTTTTATCAAATTTAATGATATCTATATTTGCATTTAAGATATAC ATCTTAAAATTTC

TCGATTTTGGTTTTTTAATTTTTATATCCAAAGGTTTTTCTTCACCATTAGGAATAG GTCTTTTTTTCATT

ACTGCTTCTCACCTCCAAAAGTATTAGTATATAAATAATTATTATTCAATAATTATA ATTTTTTAAAGT

AAAAATATACTCATATCAATCATTTTAATATATCACGATATATGATAATTAATTAAT TGATATGAGTAT

ATAAGTTATATAAAATACTGATGCCATTATTAATATTAATGCAGTTACTATATAATA TATTAACGCATT

ATTTTGCTTTTCAGATCTATTTATTCTAAACGTCATATTCATATGACGTTCTATTTC TTTAAATAATTTAT CCATAAAGTTTTCAATATCAGAAGTAGTTTTCTTAATGGGTTTAATTTCTTTAATTATTT CATTAGTATA

TTTATTCGTTTCATCTGCTTGTTCTTTAATTGCATTTAAAACAGCATCAGTTTTCTT CTTATGTGCTTCAA

ATTCTTCTTTTGTAATATATTTTTCTTTATCAATATATTTATCGTTATCTTTTCTTT TAAATATCCTTTTTA

GTAGTGCAGTGAACTTTTCCATCATCCTTAAACCCACCTTATTTTTATTTTAATAAA AGGTCGGGTACG

ATATTAATAGCTGAAACAATTATACCACTCAGAGCAGGTAACAATGCTAACCATATT TTATTTCTGCTT

TCACTATTATCTAATTTATGACTATGTGATAATTGTGTTGTTTCAAGATTCCCTATT CGTTCATCTGAAG

ATTTTGTAAATGAATCTATTTTTGTCCTAGTTTCATTTTTAACTTCCTCGATATTTG AATTAAATCTTTCA

CCAAGATCATCAATTTTATTAAAAATTTGACTTGAGAAATCATCAAATTTTTCTTTA ATATTATCTACAT

TTTGACTTATTTTAGCAATCTCTATATTTGTATCATTTAGTTTTGTTGAATTTTCAT CAGTTTTCTTCTTA

ATATCTGAAGTAGTTTGATTATAGTTGTCGATAAAAAGTTTAAATTCATTTCTGGAA ACTAGTTCTTTTT

CTGAGTTATTTGCCAAAACCTCACCCCCCCAGTTATAGTAGCCATACCGTTAAATAC CGATATGATTAA

TAGACGGTTAAAGTTTGACTTAATGAGAGTATTTGTATCGTTTACTGCAGAAGCATA AATTATCCATGC

TATTGTTGCAAAGAAACATGATATCGCTATTATAATATATCTAGAGGGTTTCTTATA AGATATAAACGC

CGATATAATGAGTAATGAACCAGTAACAACAAAGATATATGACCATATAATTATGGG AAATACCCTAT

TTAACATAATATATGTTTCAGAAGTAAGTAATACACTAGATTCGGCAATATTAAAAC TGATTCCCGTAC

TTAATGATAATAATCCTAATAGGATTAATAGAGATTGTTCCATCAAAAGAATATAAT TAAATTCATTCA

TAAATTTTTTAATTATATTTTTCATTATAATAAACAATCCTTTCAGAAAATATTATA CCATATACTTATA

ATTAAAATATATGGTATAATTATTCTCAATTAATAAATTTATACAAATTATTCGGAT GGTGGTGAATCT

AATTTAGCTTCAATAGCACTTACCCGATTTAATAATTCATTCCACTGAGCTTCAGTC GGAAATCCATTA

TCACCTTTTGCACCTTTAAGACTAGCTAACCATTCAGCTTCAGTTCCACTAAATCCA GATGCTTTTGCTA

GGTCGTAAGCAGACTTACCGTTATCACCAGTGCTTCCTTTATCGCCTTTATCACCTT TTGCGCCTTTAAT

ACTAGCTAACCATTGAGTTAATGTACCGTTAAATCCATCAGCAACTGCTAAGTCGTA AGCAGACTTAC

CGTTATCACCATTATCACCTTTTGCGCCTTTAAGACTAGCTAACCATTCAGCTTCAG TTCCACTAAATCC

AGCTAATTTTGCTAGTTCGTAAGCAGACTTACCGTTATCTCCAGTGCTTCCTTTATC ACCTTTTGCACCT

TTAATACTAACTAACCATTCGGCTTCAGTTCCACTAAAGCCGGCTAATTTTGCTAGT TCGTAAGCAGAA

TTACCGTTATCACCAGTGCTTCCTTTATCGCCTTTGTCGCCTTTTGCACCTTTAAGA CTAGCTAACCATT

CGGCTTCAGTTCCACTAAATCCATCTAATTTTGCTAGATCGTAAGCAGACTTACCCT CTTCACCATCAA

CTCCGGGATCACCCTTTGGTCCACGGTCACTATCGGAAACGGTATCATCTACGATAT CTTCATTAGGTT

TATGATAGTTAACTTGAGATATTTCATCAATATTACTAATTACATTAGTAACTCTTC CCGCTTCAGAAT

ACGTTAATACAAGTTCATCACGATCATATTTTAATGTACCACTACGTTTAATATCTT TTACTAGTACTCG

ATGATCTGAGTATATTGATGTGATTATTATTTCATTTTTGTTATGTCTATCGATGTA TTCTTCTATTCTAT

ATCCTATAGCCATTTTATTATATCATCCCTTTCGTATAAAGAAACCTTTATATAATT TTTTGTTTTATAT

ATTGGAGTTCTAAATATAAAAATTATTATGATTTGTATATATTAATAACATCTATAA TTCTAAGCTGTG

CTTCTTGATATAATTTATTCTTCCAATCTTCACCTAAGTCAATAATTTTATTTTTTG GTAATGTTTCTAGT

AATTCAATCTTATTTTCACGTATATCGGTAGTAATTACATCATTATCGTCATATACG GTTAATGATTTAT

AATTATATTTATAAAATGATAATTCTATAAATCTACCTATATCGTTTATATTATTTT TTCCTATAACTAC

TAATTTAGGTATCATATAATCATTATAATCAACTTCAATAGCATTATCGTTATCAAT ATATTCAATAGT TGTATGAATTTTATCATCTTCAGTAATTACTTCTGGAAGATTATATGGTTTAATACTGAA GTCAAAACC

ATATTTTTCAGAATAGTTATACGTATCTGTAATATTAACAGAATAGTTTCGTATTCC TTCATTTTGAATT

GAATTAATATCGTCTATATTATTAAATAAATAAATATTATCAATATTTGGTAGTTCT AAATAATGATAA

TTATTGAATTCTCTTTCTAGTACTGTTTCACTAAAGAACATTGAATCAAAAAGATAA TCATCATCATTG

TTAGAAGTAATAATAAACGTATTAATACCTTTATTAAGTTTAATTTTATTAGCATAT TCGTAAACATTT

GTTTGTTCATTATAAATGCTTAATCGATCATGAGATATACCTTGACTATTATATTTA TACGTATATGAC

AATCCGTTAATATTTACTTTTGCATTACGATTATATTTATCACTAGGATTATATCCA GTAATATATACAT

ATTTCTCAATATCATTTTCTAGGTTAATCTTAAATTCGATATTACCTTTATTTATCT TTACTAATTTATTA

GATAATAAGTTATTATAAGTATTATCAACAATCTCTGAAGTATTATCATCATTTACT GTTTTTAATGAA

GATGATAATTCATATCCTGTAATATTTCCATTAATTTTTATAGGATCGATGAAATGA TTATATATTGGA

ACATGGTTAATAATTGCTTTTCTAAGAACTAAAATATTAAAATCTACATTTTTTGTA TTTCTAGGTTGAC

CTGACTTTAATAATATTTCTTCAATATAATCATTATGGTCAGCATTAATAATATTAT TGTTGATTTGATT

CTGAGTATACATACTATACTGTTTAGGAGTTATATCTTGCCATACATTCTTGTTATT ACCATTAGTTGTT

AAACTTCTTTCAATATTATTAATAAAGATTGAAGATGTTTTAGATGTCAGATTATTA CTTCCCATATAT

ACCGTCATATTGTAATTATTCATTTCAGGAATAAATATCTTCATTCTTAAATACCCA TCTTCTAATCGAA

CATAACCCTTTCCAAAATATTTTAAATAGTCAGAAGTCATTCGTGATCCAGAAGTTT TAGTATCTTCAT

ATTCAAATATTGTTCCATCATAACATTCATATACATAAGTACCGTCAGCTAGTATAG ACGGATATATGA

CTCCATCATTATTGATATAACCATGAGTAATGATATCCTGATCAAAAATAATATCTT TTGGATAGTGTG

GATGACAATAACACTCTCCATTACAATTACACCCATTATCACAGTCATCATCATCGT CACCACCATTAT

TAGGTGGAGTAAATTTATTATTAATGTAATTTACCATTGTTATACTGGTAGGATCAA CAATACTTTGAA

CTTTTCCATTCTTATCAGTAAAATTTATTTTAAAATCTTTATGTTCTAATAAGCCAT CACGATTAATATC

TTTAATTAATGTCTTAACATTAGAATCGATTGATGTAATATCAATTAATCCTGAGTT ATGATCATCAAT

CATTTCTTCAATACGATAAACTTTCATATTTTGTTTCACCTACTATCCGTTTAATAT TATATTGTTATCTT

AAAAATTTTAGGACTTTTTGACCTATTCCATATTTAATATCTTTAAATTTATTATCT AATGACCTAAATG

ATAAAACTTGGACTGCTCTATCCCTAGTCATCAACAAGTTTGTTTTAATACGTTTCA TTAGGTTTAATTC

ATCATAACGCATTCCTGCCATACACTCAATATATGATGTTAATCCAATATTATATCT TAATTGCTTAAT

ACGCTTAGAAGCCATTAGGTTAGGATATAAGTCACGTACTTGCATAGATACGGTTAC TTCACGAGGAA

AGTTTTCAGCAGTCCATGTTTGTTCTTCGCCACGAACCATATTTATTGATGATATTA CGCCACATTCAC

ATTCAAATCTTCCTGGACAAGACATTCTAACCAAGAAAGGTTGTTTATAACTATAAT ATGCGTCTTGTA

ACGGTAAACCTAATACCAGTAAAGATACAAATGGTACATATACATAATTGAATATCG CTCTAGGATCT

CCATAAGGAGTATAGAATCTAAATTCTAAATTATACGATCTATCGAAAGTAGAGTTT GACCATAAGTC

TGGATAGTATAACTGAGAACCATCTAGATTTTCAGTAAACGCACCAACTAAGCTACC CAATACCGGAA

TTGTTTCAATAACGTCTGTTATCATATCCTTGATTCCATCAGTAATAGCACCCAATA ATCCTCCGCCGC

CAATTCCGGCAAGAGTTTTATTTTCTCTAATTTCAGCCTGTTTACTATTAGATTCAC TAGCTAAAGAAG

ACTGAGAATAATCATTAGATGAACTTTCTGATACGCTGGTTGATTTATTTGCATAGA AAGCAATGCCGT

AGTTATCACCATTATTATATTTACTAAAATCGAAAACACCTTCTAATCCCATAGAAT GATATATATAGC

TTAGTATTGTTTGTACATATCGATAATACTCTTCGTAATTTTGTTTAAACGATATAA ATCTTCCATCACT AAACTTATTTGCATTAATCATTGGAAAGACATTATCTTCAATTTTCTCTCCAATACCGAA AAGATTAAA

AGTGTTTCCTGACATACTACCAAATAATTTCTTATTTAGTCTAGGTTTTCCGGGAGT AATAAATATTAC

TGGTAGATCATTTTCGAATGTATTTCGGTACACTCTAGAGTTTGCATCATCTAATGG ACCATATTTAAG

TGGCATACCTAATACCCTTATATTATCTTTACCATATGAAGCATCAAACGTATCTAT TTTAGTATTTCCA

AAAGCATTAATAGTTTCTCCCATTGCATTGACATATAGACCTTCATTATTAACTTGT GAAGGGTCAATA

TCATCTTCTTGCATTAGTGTGTCTCCCTCAACTCCACTGTCTGGTTTTACAATATAA AAATCATCATCTG

AATCCGTATTATTATTAGAATTTTTATTACTTACTAAATCAGGCATATTTTCACCAC TTTCAAAATAAAT

TTTCCTTGAGACCAAATTTAATACATTTATGGTCTCAAGGAAATAAAATTTAATATC CCGCTAATATAG

GAGTTATACTATTAGGATCAAGTTTAAAGCTTGGTTGATCTAATTTATTATCTCTAT CATTTTTATGATC

ATTTCTAGTTTGTTTTAAGATGTTATTCGTTTCATTAGTTAAGTTATTATTAGTTGC TTCTAGTCTACTAA

TATTTCTAATTTCACGAATTAAATCACTCAATTTGCTGATAGAATCTTTATCATTCT TATCAATTAATTT

ATACATCTTATCGAGAATATGATTTACTTTTTTAAGTTCATCATATTTTTCTTTATC ATATTGGTAAGGT

TTATTAGGTTTAGCGGAACTTCCATTAGATCCATTTTTACCGTTAGAACCGTTAGCA CCATTAGATCCG

TTTTTACCTCCGGAACCATTCTTTCCACCGCCGTTAGGTTTAGCGGAACTTCCATTA GATCCGTTTTTAC

CATTAAAACCGTTAGAACCATTACCATTAGAAGAACCACTAGAACCAGGACTATTAT CTCCAGAATAT

CCACCCTTAGAGCCACCACTTTTAGAAGGTTCAGCGGTTGCTGAAGTTGAATTACTA CCATCTTTACCA

TTAGAGAAGTCTTCATTATCTCCTTTTAGACCGTATTCTTTAGCATATTTACTGTTA ATACGATCACCGA

TAGCTTTCTTTTCTTCTTCAGTTAGTTTAAAGTTAGCTCTTGATTTTTGTTCTTCAG TTTCTTCATTAACT

TCTCCAGTACCAGACAGTTCTGCACTACCATCAGCAGTACCTCCAGTGTTTCCACTA ACTCTACCAAAT

CCTACTAATCTACCAAACCAATCTGCAGGCATATTTAATGCATCACTACGAATGTTT ACACCTTTACTA

GATTCAGCATTGATCATTTTCCCTTCACTGATATAAATACCTACGTGGGAAATAGAA CCATCTGGGTTT

GCTGAGAAGAATATCAAATCACCAATAGATAGTTCATCTTTTTTAATTCTTTTAGTA GCTTTATATTGTT

CTCTAGAAGTACGTGGAAGTTTCTTACCGACAGAATTGTATGCATTCATAACTAGAC TAGAACAGTCA

AAGGTCTTAGTTTTACCTAAACCAGAACTTGGTCCCATTGAGTATGGAGTACCGATA TACTTCTTAGCA

TATTCTACGGCTTTATATCCTATAGATTGTCCGTCAGTTTTATCAGAACTTCCATTA TTGGACATTACAG

AACCTAAATTACTTCCAATATCTTTACCGGTATTTTTATTTTCTTTACTAGACGATA CTTTTTGGTTTGT

AAGATCTTTTAGTTTTGCACCCTCTTCTTTAGCACGTCTTCTTAATCCCGCTTCTTG ATTGGTTCCTGCAT

ATTGACCCATATATTGACTTAATCTTTGTTTTTGGACTAAATCAATAATTTGATTGT CTGATAGTTTACT

AATATTTTTTCCGGCTAATGCACGTTTAAATAGACTAGTTGCACCTCCAGCACCATG CTGTACTGAAGC

ACTTAAAATTAATTCTTGAATACCTCTAGATCGACCACTTAAATCAGTTCCCAGTGC TTTATTTATTTTA

GCTAGTCCTGGATTATAGAAGTCTTTTTGGAAGTATTCTTGTTGTGCTTCACCAAAT GCTTTATTTTGTC

CTAATTTTTTCCAAGAAGCATCAAAGCTAGATGAACCTGGAGAACCACTAAGCTTTT TAGCAAGGTCT

GGATGAGCTGATCCTAACCATTTAACAAAATTAGCCAGTGATCCTTTAGTAGATGAT AATTGGTAAAT

ACCGTAAGATTTACCGCCGGCATCTCCAACCCCACTAGAGATATATCCCGCACCACT AAAGTCTTCTTT

ACCAGTTTCATAAAATCTGGCTACTGAACCAAAGTCTTTTGAAAGATTCTTTCCAGC TCCGGAACCGCC

AGAGTTTCCACCAGTCGATGCAGCATTTGCATTAACGCTACCTAATCCTTTTACAAT ATCTTTTAATTTA

TCAGTAATTGATGAGAAGAAATTGCTTATTTTACCCCATACTGATTTAGATGGTTTA TTTGGATCAAAT CCATTTTCCGCCATATTATATAATGCTCCAACCGGAGTAAGACTGAATAAAGATTTAGCA AATGATTTA

GGATTCTTTTTCATATCTTGACCTACTCTAGATGACATTAATTTACTGTATTCAGAA CCCATATTCATAA

CCATTCCTAATGGAGTAGCATCTAAAAAGTCTTTAAACTTACTTTGTTCTTTACCAT CTTTACCTTTATC

ATCTTTCTTTTTCTTTCTAGCATCATTGAATTTTTCAGCAATACCCATTGGAGTTAA TCCGTATAGTGCA

TCTTTAATCTTATTTTTACGTTCTTCGGATTTTTTCTCTTTATCATTCTTTTTCTTT TCTTTTTCAGCTTTAT

CACCTTTAATTAAATCCCCAATAGAAGGTAATTTAGGAGTGCTTGCAGATTTACCTG ATTTAGCACTCG

ACATTCCTTTTACAATTGATCCTACTAATATAGAACCTAATATTGCTGCACCGCCAA CAGCTAATGCCG

GTCCGGCAATTGGAATTCCAGATACTAATGATAGTAATGCCCTTCCACCATTTCCTG CAATCCTAAGAG

CTGATGAGATTCCAGATACTAATTTTTCTCTGGTTGCATTAAATATTGCAGTTCCTC TTTCAGTAACAGT

TCTAAATGCTTCAGTTTCACCTAGACTTTTCATTCGAAACATCATTCGAGCAATTAT TCCTTTTTTACTT

TCTGCGGATTCTAGTGCAATATCTTTAGTTGCTGAAGCCATTCTCATTTTAGCTATT AGATTTTCAGTTT

TTTCACGAATGGAATTGATTGTACCCATTGGATCTTTTACTGATGAAACAATTGATC CTCCAACTTTTTT

AGCAGTATCCATAGCAAGACCGCCTGCATTTTTGACCATTCCACCAAATTTTGTATC TTTAACCATTCC

CCATACAGATCCGGCTGCATTAATGGCTCCAGATATAGTATCTTGGTTAATAATATT ATCGGGTTCACC

GCTAATGATATCACCTTTAGTTTTATTATTAAACATATTCATACGATCTTTGGTTTT CTTGATTTTATCTT

GCATAGAATGATACTTGGATACAATTGAACTACCTAGTTTACTTGAAGGATTTTTAA ATGCCGAGCTTG

CATCTTTAATTTTGGTTCTAGAGCCATAATCCTCACCGACTGAACTATCGATATTTA CAGGGTCGCTTG

CGTCAGGAGTAACATCTTGACCATTCGCATTTTTTACAAAATCACTCCTAAGGTCTG ATACGCTTGATG

CAATAATTGACAGATACCCTAGTTTCTTAGATATTTCAGTAAGAATATTTATCTTCT TCATATCATTATC

ATTATTTCCACTTGCAGAATTATATGATACCGTTGATCTATTATCGTCATCACGAGT TATATTTCCTGTA

GTTTCATTATCAAATAATCCAAATAATGCATTTTTTACTGATCCTAGAGGAGTCTCT GCTTGTAAATAT

CTTTGACCTTTTACTTGTGTCTTAAGAACATTTCTTGAAAAAGTTGCACTATTACCA TCTATAATCTGTG

ATAATTTTTCATAGATGTCTCCATCAAACATGTCTTTGTTATTATCTAATGCAGTAC GGTTTTTGATATT

_{ATTTTTAGATAATTTGATAATAGTATCTTTAATATTATCATTATCGATTCCTGCT TCACTCATCATAGAT}

TCTAATGTTGCATTCTTACTAGATTTATTTAAAAGTATGCTGAGTGGAGATTTATTC TCCGTAGAGATT

GCTCTATCCATTCCAGAATTAAAGTTATCTTTAGCTTTACTAGGATCTAACCATTTT CCACTCTTATAAT

CATATACTAATTTTTGACCTGAAGAAGCTTCTAGCATTTTTGCTAAATAACCTGGAA TTACCGTATTAA

TAGTATTATGAGTTTGAGCATCAAAGTTAACAGGTCTGTCTGCTGAAACTCTAGCCA TAGAGCTTACTT

TTCCTAGATTAGCAGGACCAAATTGTCGATTGAGTGAAGTCATTAGTGGATTTTCAC CAAAGATTTTCT

TAAATTGACCACTAATGATACTTTCGTCACCTTCAACAAGATTACCTAGTGCTGAAT GTATTTTTCCGC

CAACTTTACCATTGGGATTAGTTCGATTAAGCGTACCTTTAACCATTCTGTCAATTA ATCTTTCTTTATT

TTGGAATGGTCCAATTTCACCAGTAGATAATCTTTCAATAGTGTCATATATCGATGC AGGTATATTTGA

TACATTCTTATCAAAATAATTTTTTACTCTATCTCTTGCATATCTATTTGCTCGTTC ATTAATATTTTTAG

AGATAGAATTTTTTGCATTTTTAAGTAAGTCTTTAGCGCTTGCATTTCCAGAATTTA GACTACTAAGTTT

AAACATTGATGATGTTATTTTACCTATTCCAAATATACCAGAAAGCATATCATCCAT TAGACCCACATT

ATTGATACTTGCTTTAGCGCTTGCTTGAGATATTCTATTCATTTTTTCTAATAATGT AGTAGATTTAGAA

GATTGCTCGATTAATTGTGAATAGAATTTGATATTTGTTTGATTCATTTTATTTAAG GTATTATTTAACG TAGAAAATCCTCTTGTATTTACCCCAACTACTGAACTTGCTGATACAATAGTAGATTCAA CAATTTTAT

CAATATTTTGTTCTTCATTTACATCTTCATTATTGATATGATCATTATTATCTTGAG GAGATTCGGTATC

AATAATAACTTCAGAGTTAACGCTTGAAGTATTACTTGATTTTCGATTCATTTTATT TAATGATCTACTT

AGTATATCTAACGTGTTTTTACCATAAGCTTCAATACCCAAATTATCTTGGTTCATT GAATTATTTGAA

GTTCTATTATTCTTACTTTCCAGTTTATCGTCTAAATCTTTAGATATACTTCGGTAT ATATTATTAGCAG

ACATATTGGATGCAGGAATTCGATTATTTCCTTTTCCCCAATTTTTATTACCTTTAT TCATATTGTCAAT

ATATTTACTTCCCTCTTTAAAAGTGCTATCAATACTTTTATCTGCCATTCTAGTGTC TCACCAACTTTCA

TATGTAGAGATTAAATCGCATTATTAATCTTCTTATATATTAATGTTTAAGAATAGT AAAAATCTGATA

ACTTTAGAAAAAAAAAAAATAACCATATAGAGATAATATCTCTATATGGTAAATATA ATTTAAAGATC

AATATTAAATTGTGATTTTTCAGTTATAAGAGTATTTAATTCTTCCGCACTATATTT ACTATAACGTTTA

TTTATAGTACTGCTAATATATTTTAAAATATAAACTAGATTTAATAATACGCTAAAT CTTCTTAATTCTT

TTTCATCTTTAGATAATTCTTTTAGTTTTTTATGATATTTTCTTTCAGGATATTGCC TGCGAATATTAAG

GAAAAGTATTTCTGAAATTACATCATTAAATTTATCTATTTGAAGCTTAGTTTTATA TTCGCTAGGTAG

TTCTTCTAGAATAATCTTTTTAAAATGATCCTTGTTTAGATTATAATCTACAATAAG ATGAGTAATGAC

TGAACCAATATATAAATATATATCCATAATTTCTAAGATAGCTAATTTTTCATTATC CATAGATTGATT

GTTTACTTCATATAAATATTCTTGTACTTCTTCCATTATCTGAGGGTAAAATCTTTC TAGCATTTTACAT

TCTGTTTCTTCTGGAAATTTATACTTAGATATCATATGTTTTTGATTTTCAATAAGA TTTTCTATAGAGA

ATGAGAAACTATTGTTTTCTTCCGTAATAATTGATTTAACTTTATAAGCCAAATTTA CAACACCCACAA

TCTGTTTATTTATAAGTATTATTATCTAAAAGGGTCTTGGTATTAATCTAAATTCCT TAATATCTTCTTC

AGTATTAAGATTAAATTCAATTTCCCACTTATTTTTATTTAATATTTTTCGAATATT ATAGTCAAAAAAG

AATTCGGCAGTATCTATAAAATTTCCTAAAATACTTGTTCTAAAGTTATACGTAAAA GATTTTCCAATA

ATAATCTTTTGATTTATACTGGTCGGTATTTTCCAAATTCCATTGATATCAATTCTG AAAAGATTATCTG

GATCATAGTAAATATTAGAAAAATAATCTAATATTGTTTTAATATCACCTATATTTC TATTATAAGGAA

TAATGCTTTTCTTAGTTTTCTTATGGATAATTTTTAATATACCGTCATAATTTTTTG TTTCCATAAGCGA

CATGCCTTTCAATTAATTTTATTAATAATTTATTTTTGAAAACTGATTTTTTAGATA TAAATTTATTCTA

ATATTAGAGTTTTGTATTGAATGAGTTAGATCTATGATATTCTCATTACTATTACCA GAATTATTTAGTA

CATTTATAATTCTTAGTAAGTTTTGTTGACTTTCAGGAGTTACCTTCATACTCATAT CATTAATTATATT

ATAATCTAAACTTTCTTTTGACATATTAATATCAATAGAATCAATAATATTAATATT TTCTAAAGATAT

ATCTTTCATTCTTTTATTATCCTCAATATCCGATATAATATAACTAAGATAGAATAT TGTCCGTAGTTGA

TTTATTCGGTAAGTATTTTTATAATGAATGTTTGGATACGTTATCATGAATGGTGGT TCAATCTTATCTT

TATATTTAACATTATTATTGAATATTTCATCAATCTTATAAACAATATCCTGATACA TTCCCCTATACAT

TATGTCTTTATTGTAACAAACACTGGAATAGTATACTAAATATACATTTATAATTAA AAACGAAAAAA

TATTTATCATTAGAAACATTTTTATTTCATGAATATTATAATAATTTATAAATGTAC TAAAATTAAAAG

ATACTAGTAGTATACAAGTATTAATAGCTACTAGGTATAAAGGATTCTTATAAATAA TCTTACCAATA

GTAATAAATTTATATTTCTTTAACAATTTAGATCACTTCCATTTCTTTATATGACGT GAATATATTATTG

TATAGAAAAAATATAAATGTACAATAAATATTATAGTGCAGGTAGTTATATCTATAA TAAAATAAATA

TAACTACCTACACTGATTCCCCGATTTAACTAATACAATAATAAAAAATTGTTATTG TTGTCTATGTTG TTTGTATTTCTCTTCAAACTCAGAAGTGTATGATTCATTTAGTTTGGAGATATCATAATC TTTACCGTCA

TCTCCAGTGAACGTACCATCCCCATTATCTGTTCCACGAATCTTATCATAATTCATT ACGCTTGCAAAC

ATACGAGTTCCTGGCATACACAATGTTTCAGTTTCACGGACTTTACCAATATGAGCA TTTGTTTTCTTA

CGTGAAAATCCAGTAGAACCTACACGAACTCTTAGTCCATTTTTAAGAGTCTCATCT AAGATATCCCCA

AAGGCGGTAATCATATCAAATACTTTTCGTTTAGAAAGATCATCTTCACTAAAAGAT CCATCAGCAAT

CAGTTTATCATAAAGAAGATTTACTTGATCGTCCTTAATCAACATATCTAATTTTTC ACCACTATCTGTC

TTTTGATCAATAAGTTTATTAAGAGTTAGATATTCACGAGATTCTTTTGGTTTCTCT TCTTTTTTCTTTTT

AGATTCTTTTTTAGGTTTATCCTCTTTTTTATCTTTTGTTGAATCTTTCTTGACTGA TTTAGTAGTTTTAG

_{ATTTTTCTTTAGGTTCAACTTTTTCTTTATTAACTACTTCTTCTGAAGAAATCTT AGTAGGTTCACTTTCT}

TCACTAGTTTTTACCACTGGTTTAACAACACGTTTCTTGGGTGTTTCTTCTTTAGCT TTACTTTTTACCAC

TGGAACTACTTTTTTATTAAGTTCAACTTTTTCTTCACTAACTGCTTCTTCTGAAGA AGGTTTAACTGTA

CTCTTTCTTACTGCTCTTTTTACCATAGGACGAACGACTTTCTTCTTTTCTTCTGCC ATTTAATTTACCAC

CTTTAATTTATTTTTTGAAATATTATTAAATTAGTTATTGAATAAAAATAATCTTTT AATTCTTAACTTT

ATTTAATATATACCCTATTTTATATTAATGTAACTACCTTATTGCCAACGATATTTA ACAATATTTCACG

TTTATAATATATACTTATAATATAGGTTTAAATTTTAATTTTTTAAAGAAAAATTTT CATAACATATTAA

TATTAAAAATTATATTAATTTGATTTTCTTATGGGACTCCGATGGGACTCGCAAAAT CTGGACTGAGCC

TAGACTCCTTATTAAGATGCTTATTAATGGACTTTACTATTTTAAATCGAATTCCAA CGTTTGTTAAAA

GGTGGACAAATAGAGGGTAAAGAGCTTGCGGTATAGTAGACGATGGTCTCACTGTAG ATGTAAGTAA

GTTTGTAAAGATTCTTTATTATTTTACGTTTTATTCTTTTTTTACTTCCCACACTTG AAGAGTGTTTAAAA

GGGGGGTTGGGGGGTTTATTGTTAGTTTAATTTTTTCATAAATAATTTTAAAATAAA AATTATTTTTATT

AAAAAATAATTTAGAGTGGGTGCTGGAATTTCAGCGCTCCGCACTTCATTCCGATAA TAAACAAACCG

AGAACCTGAAGTTGAGTATTGTATCCAATTATCCTTAATATCAAAGAATGTTTATAA TAAGTAATATAC

AGTAATTAAATAATAAATATTGTATATAGGAAATATAGTATGAATATTATTCAATAT AATAATTAATG

ATTTGATAAATACTTTAATATAAAAAGTATTTATCAGTATAATATCTAATCAATATA AATATTCAATAA

TTAATAAAATTTTAAGTTAGATATTAAATATTATATTAATATTAGAATAGTATAATA AATATTAAATAT

TAGAAATATCTAATAATTATTACATATAAGGTATATAGTATTTCAATTATATTAGTA TTAATAAGTTTT

ATCAATATAATTTAAATAACAATTCTATATACTGAATGAATAAAAATAATTATTCAG AGAGGAGAGTA

TACTTTTGTTATATATCAGTGACCTAAAGAAGTATAGATTATATAAAGGTAATAAGC TTAATGGTATTA

ATAAGTTAAGTGAAAATAAAGATCCAAATAAAGGTCAATTAATATTACATTTAGGAA ATAATGATACA

GATATTATCAGTTTCTTTAATTCAAGAATATTTAAGAATAATCTATTCAAAAGTTAT TCTACAGCTAGA

AGATATAGAACTAATAATAAACGAAAAATGTATATTAAAGATCTTAAAGAACATTTT GCAAAGATAA

AGAAAGAAACAAAAGTTACATTATTTACTAAAGTAAATTATAAACAGTTTAAGGGTA ATAACTTAGTA

TATGATATTACAGATCAATATAATATTGAAATTGAATCAATTAATAATAAAAAGAAT GGTTTAATGGT

TTCTAATAACTTTATAAAGTTATTAGAAAAATCTCTGTTGGAAGAATATGATGATAC AGTATTATTAAT

TAATATGAATACATTGAACGTAGATATGGATGATATATTCAATATTACTAAGTCTAC TCATCCACTAAC

AGTTATTGATTTTATTATTAAAAAGAAATTGGATATTAGTAACTTAATTGACAAGAA TATAACAATTGT

TGTATTTAATCCTAATAACAGATTATTTTATAGTTATCCATTAACTACAGAATTATA TCCTAAAAGACA GATCATCAATCAAAGATCTAAATCACTAATTAATTTGGAAGTTAATGAAATTGAAAGCAA TGATGAGA

TGAGTAATATTCCAGACATTAATGATATTGATGATGCTAAAAGACAACTAGGTAATA ATATGAGGTTA

GGTCGATTAAGGTCTAGAAGTAAGATACCTGTTAGTATAGACAATTCTGAAGTAAGT AATAATTCTTC

ACAAGAAGACTCAATAACAACTAAAAAATTAGATGATATTGATAAAGCTAATGAAAT AAATGATAAG

GTTGAAGAAATTATTACCCTTACTAGTGATAATACTTTATTATCTTCAGAAGCTAAA AAACAATTATAT

ACAATAGCTCAAGATGAAATTAAAAATAATAAAGATTTAGTTAAGATGGATAGTGCT AAAGTTGTCTC

TATTCTTAATCGTAATGAAGAATTCAATAGAATAGTTTCAATGTCTTATAGATCATT TAATATTGGTGG

ATCGAACGCAAAAGAGCTTGCAAGAACAGCAGCACTACAAAAAAGACAGAATGAAAT CCTTAATGAT

AAAAATATTTCGAATGTATTAGCTCATGCAAATGATAAAATGATTGATAAAGGAATT ATTAAATCAAA

TAATATTAATGATGAAACATTATCAGAACTTTCTGTAAACTCTTTTGATAAGAGTTA CATTGAGAAACA

ATTTAATGCCGATATTATTAATGTGTTAAAATCATTTAACGATAATGAGGATATTAG CGTATTCATCTC

AGACATATCTTCTGAAGACTCTTCAGACTTTCAGACAAAGAAAACTACATTAAACGT TAAGCTTAAAG

ATACTAAAGGCGTTAATCATAAACTATCATTAGATATTCCTAAGATATATAACGGTA GATATATGATG

GTTAACGGTAGTAAAAAAATACTAACAAAACAGTTACTGTTAAAACCTGTAGTAAAA ACTGCACCGG

ACACAGTACAAATAACTACTAACTACAATAAAATGTTTGTTAAGAGATTTGGTAGAA AAGATACTCCA

ATGTTAGCTTCTATCAAAGAAATCTTTAATAAATTTAAAATTGAAGATCATCTTCTT TCTGGTAAAAAC

ATTAAATATTCTTTAGGTAATTCATTATTAGTTAACTCAAAATATCTAACTTCAGTA GAATACAATAAT

ATTTCTAATTATTTACTAAGCTTTAGTTCTGGTAAAGATTATTACAATTTTAACCAA AAGTTATTATTAG

AATTCATTGATAATGATGATAAACTTAATTCACTAGAATATGATTCTACGTTATATT TCCCAGTAGGAT

ATACTTCAGATAAAAGTAAACTTATCTTAGCAAATTTTAAAGATTATCACGTTTATT ATAAAGGTGCAA

CTAATAATTATGAATTTGTAGAAGAAAGTTTAAGTAGAATGATATTACTAAATATTT TGATGAGTGTTG

ATGATGAGGTTGCTAAGTTTATTGATAAGGGAATTAAAGCAAATGATAAACTAACAT ATACACGAGTA

AATATCATTAATAAAACAATTCCTCTAATAATATTATTGTCATATGAGAATGGATTA ATCAATACATTG

AATCGATATAATATTGACTTTGAAGTATTAGATTCCAATCCTAAACTAAAGATTACT GATAATAAAGTT

AAACTTAAATTTAAGGATAAATATTTGGTATATGATAATACACTAATAAGAAATTCA TTATTATTGTCA

GGTCTTCATATAATGGATATTAATGAATATAACTTAGATGAAATGGAAACCAAAGAA CCATATTTAGA

TTTATTCCAAGAATTGTTTAATAGTCGGAATGTAGCTAAAGGTATTCATAATGCATT ATCTCTCGCTAT

TGATCCTATCACCAAAGAAGTTTTAGAAGATCTGGGATTACCAACTAATATATTTGA TGTCTTATTGTA

TTCAAATACATTATTAGAAGATATGTCTTATAATACTCCTAATGATATGAATGTCTA TCGAATTCGTGG

GGCAGAGCAAATCTCTGGTATGATTTATAAGATAATTGCTGAATCATACAAGAACTA TAAGGATTCTC

TAAATTCAAGAAATAGTGCTACTAGAATTACTGTACCAAAGGACATTCTTATAAAGA CTCTTATGGAG

AGTCCTACGGTAGAGGAAAATTCTGAATTAAACCCAACATTAGAAGTTGAAGTTAGT GGTAAAGTATC

TTATAAAGGACCAAATGGTCTTAACTTAAGTCAAGGTTATACTCCTGCAGTTCGTTC ATATGACCGTTC

TATGAAAGGAATATTGTCGATGATATCACCAGACAGTAGTAAGATTGGTGAAGTTCG TCAATTAAGTT

ATAATCCTGCAATAGTTAGTACTCGTGGATATTTAGATGTAGATGCTTTAAACGGTA ATGAATCTACAA

GCCTATATTCTCCTTCTGAACTTTTAAATAACTTTACAAGCTTACATGCTGATCCAC CACGTATATCTAT

GCAAGTAACTCAACAAAAACATTTACTAACAACAAGAGTCAATAGTAAACCGCTTAT CGGTACTGGTG TAGAAAAATCATTAGCATATCAAATATCTGATACTTTTGCTACTAAAGCTAAATATGATG GTAAAGTA

GATAAGATAGATACTGTTAATAATTTAATGATGGTTTCTTACGATAACGGTAAAAAA GATATCATTGA

TATTGGAGTTGTAATGAATAAAAACTCCGGTGGAGGATTCTTTTTAGCACAATCTAA AGATATTATGTT

TAAAGAAGGTCAAAAGTTCAAGAATGGAGAAATTCTTGCAAAGAATCCTAACTTCTT TATTGGTGATA

AGCAAGGTGAAATATCATATGCTATTGGTAAACTTTCTAAAGTAGCTTTAGCTCCAT TAGACGGAACTT

ATGAAGATAGTTCTATGATATCATCATCTATGTCAGAGGATATGACTTCTAAAATTA CAATGAAAAAA

GATTTAGTGTTAGGTACTTCGGCAAACTTATCTTATATTGTAAAAGAAGGTCAAAAC GTTAAGACTGG

AGATTCATTAGCTGTATTTGAAAATGAATTTGATGATGATTCTATAAATCAGCTATT AAATACTATTGG

TGATAAATTTGAAGAAGAAATCCAAGAAATATCTAATAAAGTTGTAAAATCAAAGTA TACTGGGGTA

GTCCAGAAGATTAATATTTATTATAATCGAGAGATTGATGAATTTTCTCCTTCATTA CAAAAGTTAATT

AAAGCTTATATTTCTAAATATGAAAAGAAAAATAAGATAATCTCAGATTATATGAAA GATAGCGATAT

TGATATATCATATGATATGAATATTCCTAGTATTACTAAAATGGATTCAGATAAGAT TAAGGGTAATG

ATGTAGATGGATTATTAATTGAATTCTATATTGAATATGAGGATAATTTAAGTACTG GTGATAAAGTA

ACATATTATACGGCACTTAAAACGGTTATATCTGACGTATTCCCAGAAGGTGAAGAA CCTTTTGCAGA

ATCAGACCCAGAAGAACATATTGAAGCAGTATTGTCTCCATTATCTGTTATTTCTCG TATGACTCAAGA

CGTTTATCTAACATTATATACTAACAAAGCATTAATCAATCTGAAAAAACAAATTGG TGAAATGTTAA

AATAACTCACTCTTGAGAGAAACATATTAATATTATAGATGTGAAGGTTGCTTTGTG CAGCTTTCGCAT

CTATAATTTCTATCAAGAAAGTTGGTGAAACTAGTGGGTAAGTTAGTATCAAATAAT AATAACGGGAA

TAATGTAAGTCCTATAGAAAAAGATATTGTAAATAACTATATAGGTAGTTATATTGA AGGTACTAGTG

CATATAGTAAACTATTAGAAAATGCTCCCAATTTTGTTACCTATTACTCTAAAAATA CTAGATCATCTA

ATGAAGATCCGGGTCTTGGAGGAACGGTTGAATACGTAGGTTCAGAATCTTCACTAT TATATAACAAA

ATAAAGAATTTTCCAGTATTTTCCGTTAATGAAATAAATCCTACTTTTAATTTTGAA GAAGGCGTAGGA

CTGGATACTGAATTAGAAAGTCAAGCAATAGTACTACCTAAAACTATTATACCTTTA CCTGATGATTAT

TTGACATTTTCATATCATGAAAAAGGATATGAGTATTTTAAGACATATCGCATTAAT AATGTTTCTACT

TCTTCAATAGGTAGTAACACCTACTATTCAATAACTTTTATTAATGATCCTATAGAT ATAAGGATTCTT

GAAGAAAGACAAGTAGATAAAACTTATCGATTTGTTTATGAAAATGTAGGTACTACT GATAAAGTAAT

TATAGAAGAAGATGACATATTATTAATTGATAAAATTGAAAAGATATGTGGAGATAT TAATGAAAGAT

ATATTAATAATTTCTACAATTCACAGTTAGGTATTTTATTATACGAAAATCTAGATG AAAGTTTATTAT

ATAGTCCTAATCTTCATTATTTTATAAATAAGAATCAGGTATTTATAAATAATCGAA CTTTCATGAGAA

ACGTATATATAGAAGATATAACAAAAGTGAAGCTGAAAGATTATAACAAATCTTTAT TTAGCATTATT

GATAATGGTTATAATAACATTAATATGTCTTATCAATATATAACTAGGGTTTTGGAA AATAATATTCTA

AAGAAAACTAGGGGTCTTTATGTTGAAGATTTAGAAATTATTGGATCTAGTTGTAAT ATTAAAATTCCG

AGAACTACGATTCATAATTATTTTTCAGTAGATATTAATGATTTGATAAATAACTAT GATGGCGTAGAC

TCGTTAAATGGTATAGATGCGATAACATCAATTATAACAATTTATTTAGCACAACCA GAACAATTAAG

TATTAATACGTTATTTAATTTAGTTTCTAAATTAAATTATGATGACTATTCAATCAG TAATTATTTCTTT

ATACCATGCGTATTATCCATTATAAATATAATTACTAATAAAAAAATTACTATACAT TCTGAAGAAGTA

TAGAACTGAGAGGAACGTGAATATAAATGTTTAAGAAAATAGAAGAAAAAATCCATC AAAGAAATAT GGAAGTTGAAGCTAGTAAAATTGTAAGTGAAGAATTAGAAGTTGTTGAACCAGAAGAAGA AAAAATT

ATTGCAGTACCTAATACTTCTGAAAACAATGAAGTTTTGGGTAATCCAGAACAAGAT CCTGAAATTGG

TCAATTTATCGATAGCACTGATGAATACGATGATGAAGAAGATGCATTGATTGATGC TTTAGAAGATA

AAAATGACGATGAAGGTTTAGACGGTATTGTTGATAAAGATAATGAAGAAAAACCTG TAGAAACTTCT

GAAGTTACATTTAGTGAATCTAAAGATGATAAAAAAGAAGATAAGAAAGATGAGGAC GAAAAAGAA

GATTCTGAAGATGAAGACAACGATGAATCTGAGGAAGCTGAAGAAGAAGATGGTGAT GATGAGTCTG

AACTTGAAGAAGGAATCAGTTCCATGTTCTCTGGAATTTTTGACATCAATGAAGAAA TTGAAGATGAT

ACTAATAATATTTTAAATACACTAATCAGCGAAGAAGAAGATATCTTTATTAAAGAT GAAGAAGACGA

AAAAGATGATGAACCTATTGAAATTGATTTTATTGGTGATGATGAAAAAGATCAAGA AGATAAAGAA

ATCGAAGAATCTGATACTGATTATCTTAAAAAAGAATATCTAGGTGAAACAATACTT AATAAAATCTT

CGACAAATAATACTGTTAACATAATATTATTAAGGGTATATAAAATATAAATTATAT AAAGGATGTGT

ATTTCAAAATGCCAAAAGTTGTTATAAAAGATAATAAATTTGTATTTGGTTTAGGTA AAGGACCATTTA

ATAATCCAGTTGAGATTAGTGATGAACTTTTACGTAAATTAAAAATCTCTGGATATA CGGTAATTGAA

GTAAATGATCGTCATATCGTATATGAAACTCCAAATAATGAAGAAAAAGCTGAAGAA GTTAAAGAAG

ATCCTAAAGAAGAACTACACCAAGAAGAAGAGTCTGATGAATCCGTAGAAGCTACTG CAACTGAAGA

AGAAAATAAAGACGAAGAACATCAAGAAGAATCTAATGAAGAAAAAACCGAATCATC TAAAGAATCT

GATAACGAAAAAGTTGAAGATGATAGTGATGAAGAAGATTTCAAATCAATGAAGGTT GATGAACTTA

AAGAAATTCTAGAAGAACGTGGAATTGAATTCAAAGCTAATGATACTAAAAAAGTTC TCCTTTCAAAA

TTAGGTGTAAGTGAATAATATTTTTATATTATATTGATAGGTCTACTTGTTGAAATT ATAGCAAGTAGA

CCTATTTTTTTCGATTATTATAAGTTAGATAAGAGGTGTTTATGTGTGCCAAAAGTA ATTATATTAAAT

AATAAATATATACCAGATATTGGTAGTGGTCCAATACTAGAACCAATTGAAATCAGT AATGAAAAATA

CCATTATCTAATAGATAATGGTTTTAATATATATCAGATAGACGATAATGAAGATAT TATGATTGATCC

ATCCATAACTACCATATTGAAAGGTAAAGTTAAGTCAGTATATGGAATGTTTCATGC AGATCAGAAAA

AACTTGATTCACTATTAATGTTTAATAGAACAAGCATATCTTCATTAAAAAATGTTA ATACTAAGAGTA

TTACAGAAAATAATAATATAATATATTGGAAATCAATAGATACCGATATTGCATATG TAAATTCTGAC

GGTTATATTGCTGCAAAAGAAAATGGTTCCACAATAGTTACTGGTTTTGATTCAAAT AATACGCTTAAA

GCAATAATGTTCATAACGGTAATACCTAAACTTCCAATATTACCCAATGATATTAAT GTTAATTTAGAA

AGCTATATGGAACTTAATAGATATGCAGAATTTCAATACTTAGTTGAATTACTTCCT AGCGAAGTAGAT

AATAATAAAGTAAGTATTACATCAAATAATATACAAATTGCAACTATTGATGAAAAG AATAAAAGAA

TTATTGCTGAAGAACCTGGATATGCTGTTATTAATGTTAAGAGTGCAGAAAACCCTG AAGTATCTCAT

AGTACGTTGCTAAAAGTTTTTCCTAATGATGATAGGAATAATCCTTCTAATATAAAT GTAAATATTCCG

GACGAGATTACAATTAAGGTTGGAGAGGAAATTCCCTTTGAAGTAAAAATTACTCCT GAGTCGGCTAA

TAATCTAGGATATATGTCTTTCTCATCAAACGTTGGAATTGTATCTTTATTAGATAA TAACCATATTCTT

GGTAATAGTATTGGCGTAGCAACCATAACTATTGTATCGAATAAAATATCATCATTA TATAAAGAAAT

ACGAGTTAATGTTGAAGCACCAGACCCTAATGATATTATTGTAAATTTAACTGAAGT ATCTATTGAGA

AAGGTCAGACTAGAGGGTTTAATGTAACAGTTCTTCCAATATCAGCTAATGACAGAA CTTACAGTAAT

AGTTCTTTAAATGAAAATATTGCGACTGTAACTCAGAATAATATTATTACCGGAGTT AATATTGGGGA CACAAAAGTAAGAATAACATCTAATAAAAAGCCTGAATTATTTAGGGATATTATCGTGCA TGTTACTC

CGCCAAGCCCTAAAGATATTATGACTGATCTTCCAGACGAGATTACAATTACTGATA CCGAAACTAGA

AATTTTACAGTTCAAATTCTTCCTGAAGATACATTTAACAACAAATATGATATGGAA GTAACAATTCCG

GATATTATTGATCTTGATAAAGAAAATTTATCATTTAAAGGTAAAAAGATAGGTGTA ACTAATTTAAG

AATTTTTTCACAGTATAACCATGATATTTTTAAAAATGTTAAAATTAATGTAGTACC AAGTCCATTACC

TGATCCGACATCTTTTAAAGTTATTCGTAGAGATACTGGGGAAGAATTAAAAAATGG AGATACTGTAC

CTAGTAATAAAGATATACTTTTTGATGTTATAGTTTTACCAGAAAATGCCAATGATA AAAGTTATATAG

TATCATCTTCAGACGTAACGATTGCAAAAGTTAACTTAAATTCTATAATAGGAGTTT CTCCGGGTCAAG

TTAATATTAGAATAACATTAAACAAAGTTTCAACAATATTTAAAGTATTTCAACTTA ATATTGAAGAAC

CTGTTCCTACATTAATTGATATTGATGTACCAAGCAATATTACTGTACAAACTATGC AAACACGTAATT

TCACTGCAACTATATATCCTGAAAATACTCCATACCAAAATTTCTTAACATCTGTTG AAAATCCTGATA

TAGTAACTATTTTAGATAATACAAATCCAAAAATACGTACGATTAAAGGAATAAAAC AAGGTGTAACT

AAGGTTAAAGTGTATTCCGAATTTGATCCAACAATATTTAAAGAAATTAACGTTACA GTAGTTAATCCT

AATCCTAGTTCAATAGAAGTTTCTCCAAGAAGTATTTCAATGTTATTAAATGAAACT AAAGAATTGGA

TATTAATGTATTGCCAGAATATGCTAATGATAGAACATACACTATTAAACAAACAGG CTTAGGTATGG

TTTCTATTAATGGAAATAAGATTACTGGTGTGTTAAAAGGAAATGTAAGATTAGATA TTATATCTAAC

AAAGTAAGTTCTCTTGGAACTACGGTATATGTTACTGTTGATAATCCTGACCCTGAA GATATGATTGTC

GATATACCTGACGAGATCGATATCAATGTAGATGAAAGAAGAAATTTTGGCGTAACA TTTGTTCCAGA

AATAGTTAGTGATGATTCTATTATTATAACATCATCTAATTCTAGTATTGCTATAGG TAGTGCTGTACA

AAAATTTATTAATGGAGTTTCTGTTGGTACTGCAACATTAACTATTAGATCTAATAA AGTAGCTACTTT

ATTTAAAGAAGTTATCGTAAATGTTCATGAAGATAGACCTGACCCAACAAGTATCAA TGTTGGAACTA

ATCCGCTTACTTTAGAATTAGGTACTACAACTCCAATAAATATTGCATATGAACCAG AAATTAATAGT

GGTGGTAAAATAATTGATGATTATTCCACATCAAACACTATTATTAGAATGGATCAA TTTAAAAATTC

AATACAAGCTATTCGACTAGGATCTACTAGTATTAAATATACTTCTGAAAGATTTCC AAATATTACAAA

TACGCTAAATATTACAGTTATTCCTCCTAGACCAAAAAGTATTAGTGATAACTTTTC ATATAATAATTC

TTTAAATGTTAATGAAGCAACAAATAAATCGTTAATTGTTAGCTTTTTACCAAGCAC GGCGGTAAACA

TTGGATACAATGTAGTTATTGATGATCCAACTGTTTTATTATTTAATACAAACTCTA AGAAATTTGAAG

CATTAAAAGAAGGAGAGACTATCGTTAAGGTGGTATCTACTGATAATTCTTCTCTAT TTGTAGAACATA

AATTTAAAGTTAATAAAAATATTATTATCGATGACGGTGGTAACGGTAAAGATGATG ATGGTAATGAA

GTTATAGTTCCAAAATCAATAACGTCAGATATAGTCACTGAAATGATAGTCGATAAG AACTATCGGGT

AAACGTAACAGTTTTACCAGATAATGCTATTGATAAAGGTTTTGAAGTTATAACTAG CGATAATAATG

CGTTTAATATAGTTCAAAACAGTGGATCATATTTTACTATTAAATCATTGGTTTCTG GAATGTATAATA

TTACGTTGCGATCTACATTAAATCCTAATATAAGCGTATCTTATGATATCGTGTCAG GCACTGAAGATG

AATTACATCCAATCTTACCAGAAACAATAAATATTATAAATGCTACTGATGAAATGA CTGTAGATGAA

GGTACATCTATGAATTTAGATATACAAGTTCTACCAGAAAATTCAACTAATAAAAAT GTAACTGGTTA

CAGTAGTAATGAAGAATTAGCAACTATACCTAATAATAAAACTATAAGTTTTATTAA AGAAGGTTCAG

TAGACATTACAATTACATCAAATAAAGTACCTACATTAAGTAAAACAATTCACTTTA TTATTAAAAAA CCCGACCCTAAGAGAATTGAAATTAATGCACCCAACGCAGTAACTTTAAATATCGGTGAG TCTAAAGA

ATATCTGATAAGTGTAATTCCTGAAAATAGTATTGATAAAGAATATATTTCAGAAAC ACTAGATTCTA

GTATTGTTACTACTAATGGAAAAAATATTATTAAAGCGGTTAAAGAAGGAAACACTA CAGTTGTGTTT

AGGTCTAAAACTTTTCCAGATATATTTACACGACTTAATGTTATTGTTCTTCCTCCT GAACCGAATGAA

ATAATTGTATCTCCATCCAATGAAACAATTAATATGATTAAGCTTGATGAATTAGTA TTTGATGTAACG

ATTAATCCCTCAAACGCAATCGATTTAACATATAAGATTGAGTCAAGTGATACTAAT ATTGTAAAAAT

TAAAAATCAAGATACAGTGGTTGCAGTAAATCCCGGAGAAGCAAACGTGACTATATC GTCTAGACGG

AATGCTAATCTAAAAGTTATTAAAAAGATTATTGTAACTGCGCCTGACCCAGAATCT ATAGATGTTATT

GGTTTTGGACCAGACGAAACAATGATTACAAATTCAACAACTAAGTCCGTTAATTTT ATAGTCAATCC

GGCTAATGCTAAAGTATCTAACTTTACAGTAGTATCTTCTAGTGATTCGGTACAAAT TAATATTCCGGA

TCAAACAAAATATGGATTTACTGTAAAACCTGTTAAAGAGGGTAATGCAATTATCAC TATCCAATTAT

CATCATTCCCAGATATTATTTACAATATTAATGTAAGGGTGAATAACCCTGATCCTG AAAGCATAACTG

CAGGGATAACTAATCCTCCAAATATGCCTTCTGGAAATATTCCAGGAAAAGGAATTG CTATAGGAGAG

AAGGTTGTATTAAATGCTAAGATACTACCTGAATATGCTAATGATATAACTTACTCA ATTAGTAGTAGC

GATAATGATGTCTTTGAGGTTCGAGATGATGGAATTTATGCATTAAAAGCCGGAACA TCTAAAGTTAG

GGTATTCTCTAATAAAGTTCCAACAATATTTAAAGAATTTGATTTAGAATGTCTAGG TAATAATGTTAG

TGATATTGAACTGGATATTCAGTCACCATTCAATATGGTCGTTGGTAATACGAAACA AATAAGTATAA

ATATTCTTCCTACTGATGCTATTGATAAGAGGTATCAGCTTAAAACAGATGACGCTA ATATTGTATCGG

TATTAGATAATAATACAATACGAGCTATATCTCCTGGGGTAAATGGTGAAGGATTTA CGAATATACGA

ATAATATCTTTACGTAATAATTCTGTGGTTAAAGTAATACGAGTTAATGTAGAAAAC TTAACGCCTCAA

AGTATTGATCTTGTTCCATCTGGACCCATAGAAATATATTCATTAACATCAACTACA TTTAATGCATAT

GTAAGACCAGACACGGTAATTGATAGGGATACGGTAGTTAGTAGTTCAGACATTTCA ATAGCTACGGT

TCAACAATCATATATAACTGAAGGTGGCATAAAAATTACTAGAGTTACCGTAAATGC ACTTAAATCTG

GAAATGTTAATATTCGTGTATCATCTAATAATTATAGAAATATTTTTAAGATGATTA ATATAAATATTA

TTGACCCAGATCCGGAATCAATTACTGTAACTCCATTAACAATAAATATGGCTCAAG ATACATCTACT

AATTTTAATGTAAATATTCTTCCAGAGAATGCTAATGATAGAACATTTAATACTGAG ATTGCAGATCCT

ACAATTGTTTCTGTTAATGGAAATACAATTACTGGTCTTAAAACAGGAACGACTACA GTTAAAGTATC

TTCAAATAAAATACCATCATTAAATAAGACAATCACAGTCAATGTGAGTCTTCCTAA TGTAAATAAAA

TTGAGATTACTACTGCATTAGTTGCGGGAACAGTTAATACTGTATATGAGGGCGAGT CTTATCCATTTC

TTATTAAGTTATTGCCAGAAGTTGCTGCAGATAAATCATTTACGATAAAATATTCTG CTAATGCTGATA

TGTCTGGTACTGCTGATTACTCATTTAATTTTGGGTATCGTAATGATTCATTAAATC CATCACTATATAT

ATCAGCTACAAGTTCATCTAGATATGTTCCACCTTTTGTTAGATATATTCAAGTGGT TTCAGCTAATGG

AATTACCTCGGATATATATGGTCTAAGTGTTGTACTTAAACCGATATATAAAATGGA TAGTACATTTAC

ATTTTATAATGATCAGTACGCTTCTGCTAAAACTACTATATCTTTTGATAGTACTAA TCCTAATTCTGAA

AATTATGTAATTAATGCCTATGCCGGAACAACAGCTAGAGACCCTAATATTAATACT GTTAATTTATAT

CCTCTTGAAGCAAAAGATACAAATTTAACAGTTACTATAAGTGATCCTACAAAAGCA TCATATAATAG

TACAACTAAGACTTTTACCGCTCTTCAATATGATACTGAAACTACTGCAAAGATTGC ATCCACAACTAG CCCTGATGTATTTGTAATTGTTAAGATTAAATGTATGAGATCTAGAATAACGTCTGTACA AGTTACAGG

TCAGAATGGATTAAGATATAGTACTGGCGATGTCTTTGGAATAGTAGTAACAACTGG TCCAGAAGGTG

CTATTGATACAAATGATTATACATTATCTTCAAGTAATGATACTATTATATCAATAA ATAATGAAACTA

GAACTGGAGTTGCTTTAAAGGCAGGTTCATCAACTATTACCGCATTATTTAATAAAG CCGGCGTATCA

AATAGTGCTAGATTTACTATATCTGACGTACTTCCCACTTCAGTAGGTATTACTGAC CCTCCAGGAGGT

TCTGAGCTAATTATTGGAAGATCCTATCCGATAACTCCAAGTGTATTGCCGACTAAT ACAACTAATAA

AGCGGTAACCTATTCTGGAAATAATTCAAGTTATTTAACATTGTCTAAAATAAATAA TATTGATTATAT

TAATGTGGTGGGTAAAATTGCAACAAATACACCTATAACTATTCGATCAGTTGCTAG TACGGGAATTT

ACAGTACAGTTCAATATAAGACTGCGTATGAATACCCAACAAGCATTGATATATCCA AAATTAATGAC

TCATATAATTTAACTGAAACAATTGACTTATCTACTTTGATAAATATAATTCCATCA AATACCGATAAT

GATAATAATTATACAATAACAACTCAAGATACCGATAAAATAAATATTGATGGTAAG AAATTAACATT

TATTAAAGATGGTAGTGCAACTATTACAGTAACTCATAATAGAAATAATATTTCCGT TAATAAATTGAT

TAATATTGTATATAATGATTCAATTAAACCGAATATTGTATTTACTACTTCAAATAT TATCATAAATAA

TAATGAATTTGATATTAAAAATAATATTACTAAAGATTTAACACTAGATGAATACCT CATTACTGGTGA

TCTTAATGGTTGGAGATATAATGGCAATAAGAAGTTTTCAGATAGTGGAGATTTTCA AATTAAATTTA

ATTATCCTATTAATATGCTTGAATTTGAAAGTATTAATGATCAATTTTCAAGTGAAT TTATGTATAATTT

AAATAATCCGGATTCTAAAGTTGATCCACCCCAATATGTTGACCTTGATAGGGGTAG TGATTTGATTAA

TGATCGATTATTTAGTATATTAGATACGTATACCATTTCTTCATATTATAATAAACG AAGAAGTACTAG

TGGTAATGAAAGTCAATCATATATTGTAAGCGCTTCACCAGTAATAAATAATATATC TCCTGCAGGAG

AATATTTTTATAAAGTCTATGTAAAGAATGATCCTAATAATTATATTATTATTAGAA TTAATATCGGTA

TTCATGGATCAAAACAATCCAGTAATTTGATATATAATGGATATCCTACTCTCATTA GTCCAGTATCAA

TATCTACTGATGATAATATAAACTATGAACTTAAAGTACAGCTGTATTTAAGATCTA AGTGGTTGAGTG

GGGACAAATCACCTTTATTATTTAATAATGAGTTAATTACTCATCGATTAATGCTTG ATTCTTCATATA

ATAATAAAATAAATATTAATGGTATTGAATATAATAACATTAGTGATTTTATTGAAA TTGATAATAGA

ATTATTAATCGAATAAGTAGACTAGGTGTAAATCGTGTAAATACTATTACCGATACT GTCGCATCTATT

GATAGTGTGGTCGCAGCATATCCGGACAGGGTAAGTTATTTTATTAAAAGAAATCCT ACTAAAAATGA

AGAATTTAGTATGGATATAAGATTAGTAAGTATTGAGGATTCGAATATCAAAATTCC AGTAACTTATA

CATTCACTACAATTAATAAATAATTCTTTCAAAGAAGCATATGATAAGATTCTTGAA AAGAAGATTAA

AAAAAAAAAAAAAAATAAATCTCCCATAACCTATTAATTTAGGTTATGGGAGATTTT ATGATTATTTA

TTAAACAGATCATCAATATTATTAGTATCGATATCTTCTTGAGTTTCTTCCTCATCA TCTTCATCTAACG

GTACAAAATTGATAACTGGTTTATATCCTAATGCCTTTGCAATATCTGATAGACTGG AATAAGATGTCG

CACCTTTTTTCCGTAGTCTGTAAAAGATATTAGAAGCTCTTCCTTCATTATTAGGAT TATCAAGATCAA

ACTTTTCAAAGAATTCTTCAAATGTTTTACCTTTTTCACCCTGCTCATTAATGAATT CTGCAGTAATTAA

TGCTAATTCTGTTTGATTTTCAATAGAATCCACATCAATATGCAATGGACCAGTTAA TTTCTTTCGTTTA

GATTTCTCAGAAGGATCTTTAGAAGCCTTGATCATACTATCTTTCTTATCTAATTTA TCCATATTTACAT

TATTTAGTTTTGAAAATAGATCATCGGACACGAGAATTTCACCTCATTTATTATTCA TATTAGAAATCC

ATATCATCATTAGAAATTTCTTCAGAAGCACCAATCTCAGTTGATTTTGCAATTAAT GATTTAAGATCT TTTGATCCACCACTAGCTTGGATAATTTCTGTATCCACATCTTCTGTTTGTTTATCTGCA ACTTTTTTCTC

GGATGATTTAAAGTTACTACCACTATTATTACTGTTATTAAATGTAGAACTTACATT TTTAGGTTCAGT

GGTTGTATCATTTTGTGATAGATTGTTATCATAAGGATGTTGAGTTGCGTTTGGATT CTTTCTAGTTACT

CGATTACTATTGAATCCACCACTTGTGTTTCCTGAACGATTGAATGGAGTTGTTGAT GTAGGTCTATTA

AATCCACCAGTGTTTGGACGTTGACTAAATGAACCACTATTATTAGATTGACCTTGA GAATAATTTCCT

CCGCCCAAAATATTAATAACGTGATCTAATTTATTTTCTACAGTATATAATTTCGCT TGAATTTTCTGGA

ACTCTTGTAGAATATAAAGATCAATATTATTAATACAATCAATCATATTGAATAATT GTAGTGTAGTTA

GTTCTACTGAATATTCATCGCCATTTACGCATAAAATAAATCCTGGATAAGTAGTAT CATCATTACGAT

GAATGATTGAAGGATAGATTAATAATTTTTTACCTTGACCACCAAACTCTGGAGAGA ACCATTGTGGT

AATTCTGGAAGATCCCATACACGATTACCTGAATTATTACCTTCAATAATTTCATTA GCAACTTGGTTC

ATATATGATTTTAATGTTTCATGATGAGCCTGACTAACTACAACATTCTCACGAACG CTTTGATTAGTT

TCAGGATTAAATCGACTATAATCAAAACGTAAAAACACCGTTGCGCTGTTTTGAATA CTAGTTAACGT

TTGAACATCGGAATATCGATCTGAAGTGTATTCTCTTGCATATTCAGCATCCCTACG TTTATCATTAGTT

GATGTTTTATTACCTAGTAATAAAGAACTTTCTAGTTTAAAATTGAAAGCACTAAAT AGCGTTAGACCA

TGAGATTCTACTGGATTAAAATTTGACAAAATATGATTCCTCCTAATAATTTTATAT ATTACAATAATA

TAATATATGATTATAATTTATTTTAAATGATTATTCATTTGTATCTTGATTTAATGA TAATGCAGTAAGT

CTGGAAAGCTTACTAACAAACTGACTTCGTATAATTGATGAGTACAATGCTTCTTCA GGAACATTAAA

CATTTCACCAATCTTACTGATACTGTCACCTGAAGTATAATCTAAGAATTGATATAC ACTAAAAATATT

GATAGGTTCAGGAATGATATATTCTGGAATTACTGGAATTTTATTTTTAAATAAGAA AGCTTTATCTAA

GAAATGAATCCAATCTATTGGATTATCTACCCAAAAAAGTATTTTATTTTTTCCTGA ATTAGAAAGCTC

TAATAACAATGATTCAATATTATTGTATATTGTTGCATCTTCATCTTTCATAATTCT AATATTTTTGTTA

GCATCATAAGTATAAATCTTTTCAACATTATTCGCTAGTTGATTATTATATACTTTC ATACTATCTTCTT

GGGATATAGCTGTAGCAATATCGTAATTTGTAAATTCATAATAGTAATTAGATATTA CACCTTCTGCTT

CTTCTACACCCAAACACATATTCATGATGTTAGATGACGTACTAGACCCATCTAACA TACATGATAAGT

AAATATTTACAATCTTAGTTCTTTCCATATTTTACCCATCCTTATTTAATTCTTTTT GTTTTTTCATTTCTT

TATTATAGAATATATCATGAGTTAATAAAAATTTGAAATTAAGTTCAGAATTAATAC TATTGATAATAT

CTTTAATACTTTTATTAATAACTGCAGGGTTTGTTAAATCTTCAAGAATTTTCTTTT CCCTAATATCATT

ATTAATAGTTAAAGACATATCAAGTAGATCGTTTTTAATTTTATGATATTTTTCAAA TTTAAGTTTACG

ATGTCTATAGAAAAAACCATCACTATTATTTTCACTATACATCTTTAAGAATGATGC ATATTTATTAAA

TAAGTCTTCCCTTTGAATTTTAATTTCACCTTTTTGGAGTTCTAAAATTTCAATAGA CCTTTTAATATGG

TTATTAATTTTTCTAAGTTGAGTTAATTCAATATCAATAATCTCTGTAACAAGATCA AAATTTACAATT

CCGATAATATTACCGTCAATATTAATATTAAATCTAAGAATATTAAAGTCTTCTGAA ATTTTAGCACCA

ATTAATGAAAAGATATCTTCATCATACTGTCCAGTATTAACATTCTTTGTTAAAGAA TATATAAAATCT

TTCTTAATACGATTCACAATCGTATTAAAGATATTTTTACTAGCGATTAATTCTTCA ATGAATTTTGAA

GGATTTGTTTCTGAGAGGGAATAACGATCGTTAGATGCATACAAAATTTTCACCACT TTCCGCTATATA

ATTTCCAATTTAGATTCAATAATTTCTTTACATCTTTTACGATAAATTTTCTTTCTT TTAGTTAATTGACG

TTTACATTCATCAAAACCTGTATCAATGACATCAAAGTATAGACATTCTTTATTTTT TACCTTACGTAA ACGACCCATAATTTGTATCAACCCTTCTTCAGAACCAGAAGGTACAGTATTTACTAATAC TCGTAAAG

ATTGTTCATCTAAACCTTTACCGAAAGATTTATCCGTAGTAACAATAATATCTTTTT CAAACGCAGTAG

_{ATTTTTCATCTTTAGGAACGTCTGAATAAAATCTACTTACCGATATATCCCACTT ATTATTTTCAATTTC}

TACTAAGAAATCTTGGTAGAAAGCATTAACCATAATCTTATTTTTAAATAAGATTGC AGTCTTTCTTTT

ATTCTTACCTTTATCAAAGATAATATCGAAGATAATCTGATAAATATAGTTATAATA TTCATCATGCTT

TTTATCAATAATATACTGAGAATAGCTTGGTACATTAAATCCATAACCTTTAGATTT CTTTCTAATTTCA

ACTAAATCTTCATTACTAGGTTTAGTATCTATTTTACAAATGATTGTTCTAATGTAT CTATCACTATCAC

TAACTACAGTAGAGAATTTTGGAACGTTCATATACATATTCTGATAAACTTTATTTT CAATAGGATTAG

ATCTACTAGGAGTCGCAGTTAAATATAATGATGGACAGTCATAAGTAGAATCAATAT TAAATACAGAA

ATATATTCAACGTGAGCTTCATCATAAACTTTAATTGATATTCCAATTCGATTAAAT AACTTTACAACC

CTATCAGGATCAGACTGAATTAATTGGTTAACAGTCTTGTGAATAGATAAAAAGAAT TTATACTTAGA

TATATCACGTTTAGTCATCTTTTCTAATTTTTCAATAGATTCTATTCCTGAAATAAT ATAAATATTATCT

AATGATACGTCTGTATATTCACTAATTCTATCCTTCCACTGTTCTAATAATGATTTC ATATCAATAAAG

ATAATTGGTACTGCTTTGATTTTATTAATATAATTAATAGCACAAAAAGTTTTCCCT TCACCAGTCTTTA

ACGATAAAAACTTTTGATAATAATTATTATCATCATTAAGAAAATTCATTGCATCTT CTTGAATTTTATT

TTTAGGTTTATATTTCATTTTAAAATTATTTTTCCTAAGAATATTTTTATTTCTTTT ATCATTAATATGAA

TATTAACATTTTGTCTTCTTCTTAAGTTACTAGATAAAGAATCAATATCAATACCAG AAGGAAATATTG

CTTTATCATCATCTATCTTGTATGCTTTAAAATCATACTTAAACCATTTAGCATTCC ATACAGAAAGAC

TATTTTCTACAGCACTAGCCATTTTTTCGCTATAGTTATTAATAACTATCCTTGTTG GATAAATATCAAG

ATCCATTCATATATCACACCTTTATTAGTTTAAAATCAATAGAATGTATTATATAAC TAAATAATACAT

TCTATTGATATATTTTAATTTAATATTCTTTAAAGAATAAGTGAGGAAAAGATTCAA AGAAATTAATAT

GGTTAAGTTCTTCAGGACTTTCAGCATCTGTAGCATTAATAATGTAACCAAAAATAG GGACTTTTGAA

GTGATATAATATTTACCTTCTTTAAATGGACCAACTGTCTTTTGACATTTATCCATT AAATATAATTCAC

CATCTAACTGGTATCCTACTGAAAGTTTATCACCTAGTTCATACATTGATAAAAAAT CGGTATTATTAA

TAAATTCTGTAAATTCTTTTGGATTATTGGTATATCGTCTGATTCTAAATTTATTTT CATCTGGAATATT

ATCTAAACTAATAATAAATCTATTTTTTTCTACTTCTTCGGAATCAATTAAATTATC TTTGTCCATATTC

ATATATCTATATATCTCCCTTATAAATAAAATTATCTAAATACCCTATCGAATTCAG ATTCAACATCTTT

ACCAAAAAGATCATTATAACTATCTGTCTTAAATTGTTTTTCAATATTTTGATATAA TAGTGACATTGC

AGGACTTTTCTTACCGATAAGTATTGCATCACTTACATTATATATATTATATTTTGG TAATTCTTCAGCA

TTAGCAAATTCGGTTCTATCATTATTTTCTAGACTTACCATTTCCCTTACAATAGTT TCTACATGTACAG

AATCAATCATTGTTCCTGAATCCACTAATAAGTTTACAATTTCTTGTACAATGATAG AATAATCATTAT

TTGATACATTTCTAATAAAATGATTTTTTTCTAAGATATCTTTAATCTTTAGAAGTG GGTCTGCAATACC

ATCATTTTCCACAATAATATTAAACATATATTCATTATCAGGCATATATTTTAATGA GAATACATAATT

ATTTGTGGAATTATCATAATACTGTTCAATATCATCCGCAATCTCATTAGGAATAAT TAAGCTTAATGG

AGTGTCAATTCTAATCTGAGTGTCTTTCCTACCTTTAACATAGATTGTTCTTGTTTG ATATTTATTCTTTT

CAGAGTCTTCATTTTCCATAAGATCATCTTTATGAATATAGATTGTTTCATTATCAG AAATAGGACTAA

CCTTATCTTCAAATAATTGAAACTTAGATAAGAAATCTTTAGACCAGTTAGCATCCT TAATAATAACTT CTAATAAATGCTTTGTTGATAAGATTTTTTGTGTTAATGGATTAGTAAGTTCTAAAGTTG CAGCAGTTC

CTACTTTAATGTGTTTATTAATCTTTTCTAATCTTCCATAACATCTAGGACATATAC CTTTTGAATGTGC

GCATGTTATTGGACTAAATATCTTAATATCTTTACCAATAAGATGTGTATCATTCTT AGTTATTACGGT

AGTTTTATTAGTATCTTCATCATACATCCAACGATGATTATATAGTGATAACATGTC TTTATCTCTAATA

TGAATATTAATATAATGAGAAGTGTTACAACTATCTACATTATTTTCATCTTTGTGA AGTTCTTTATCTT

GTGGATCAATATCTAATGTGTATATTACTGAATCTTCAGTTAATATAGATATCTTTC GGTTAGTATATC

CAGACTGTTTTACTTGATCCTTTGCAGTGATAATTGCTTTTCTACCACCTACTGCAT CAATAAAGAATTC

TGTTACATTTTTAATTCCCCTTACAAAAGAACTATTAATTGGAGTAGTAATAACTTT ACCATATAGATC

GGGCTTATAACCAATTAATCCAAAATTTTGATTAAATTGTTTTATATTAATTCCTGC ACCCGACATGAT

TAAATCTCTAGTAATATTATCTTTATCTTCTTTAATAATTTGAATCATTTTATCTTT GTTTTCTGCAATTT

TTTGATTATTTGTTCCAATATCATCTTTTAATTCTGGATCAAGTTCGAATTCTAAAG TTTTCTTAAATTC

TTCATTTCTATCCATAATATCGATTATATCAAATAAACTATAAGTCACTCCGCTCTG ATATAATACGTTT

TGAGTACTAAATATTGATAGTTCATCTACTGACCACGCAATATCTTTTTTAATCAAT TTTATCTTTTCAT

CACTAATATCATAATTATAAATTTTGTTAATAATCTTATCATAAAATACATTATGAA GATTAACATTAT

AATTACCCTTTTCATTACAATCTTTTAAGATAAATGTAAACTCTTCGGTAAATTCTT CTTCCAAACTCTT

AAAAGGTTTTGCCAAAATAAACGTTGTTAATAAATTTGACCTAGATATTTTTGATGT TCCAAATTGTAA

AATTTCTCTACGAGAATCCACATCTTCTACAATTTTCTTTCCTAATTCATCAATCTT CGAATAATACTTA

GTATCATCATGAAGAATTGAATTAAATAAAGATAGATCTAATACTGTACTCAATATC CTCCACACAAT

CCTTTCTGTAATATATTTAACCACAAATATATAATATATAATTGTAAGATAATTTAA TAATCACAAACC

TATATTATGATTCTAACAGAATATTTCATTGTTGTAAATTAAAATTAACTTTTTATC TTATGAAACTTAA

TGTGGATCATAGAAAATTTAAACTATCAATAAAAATATATATTATATATTTGCGAAT AAAATCCCCTAT

CATATAATTATAACACAAATTTATATGATAGGGGAAATAAATTATTTATCTTCGACT TTTTTAGATTCT

GATTTAGCTTTACGTTTTTCTCCGAATTCACGAAGTTTTTGTTTTCCTTTGCTTGCA TACTTAAGTTGAA

TTGCTCGGCGAGTTTCTCGGCGCAACTTAGAATATTTAACGTATTTACGGTAAAGTG GATCATTTGCTT

CTTTAGCGGAAATTAATACTGCTTGAGTATATAAACGTTTCTTAGCGGTACGTTTAT CTAAACGAACAA

TATTGGCTTCTTCTAGATAGCTTAAAGATTCTTCCAAAGTTTGCATTGAACTTTCTT CATTATTATAATT

AAAAAATGTATCTTTCATATTGATTAAGCATCCCTTTCTCTAAATAAAATGGTTTAA TAATTATATGTTT

ATCAATTCAATGCAGAAAAAATAATAATTTATTTTTATTCGTTAATAATGTTTTATA TTATATAAAATA

TAGAAAGGAAAGATAATTTATGTATAGTTTTTAGTAGTAATATTCTCTTTAATTATA TAAAAAATAAAA

TTGGTGGTGTATTGTTTATATGAAGATTGAAGAAAAAGAACGTGAAATGAAACATAT TGGTTACATGA

AGATATTACTTAATGTTGCTAAAGAAGAATTTCCAGATATGGAAGAAGATGTATTAA AAGAAAAGATT

AAAAATATTGTAAAGGATAACATGAAAAATCCAAAAGCAATGATTGATGATCGTGAA ACAACATTAT

TAGGATTAGACAAATTTATCGTAACTGAGAAACCTATCATTACTGGTTTTGGATCAA TGTATTTAACTC

ATGATAAGTTTGATAATCTATTAGCAAAATTGGTTGAATATATTATCAAAACTCGTA AAGTTTATAAAA

ATAAAATGTTCGAACACGTTAATGATGATGATCAAACACTGAGAAATATGTATGATA TGTATCAACGT

ACCATGAAGATCCTAGCGAACTCATTTTACGGATCATTGATCCAAAGTAGCTTTATT TTGTATAATCCG

ATATCTGGTCCGTCAGTTACTTATTCTGGTGTTGATATTATCACTACTGCACTAAAT AATTTTGAGAAA TTCTTAGCAAATAATATCTATTTTAGAAATGTAGATGATATTATTGTATATATGAATAAT ATTAAATCT

GAAAATTATAGTATGGATAAAGTTAAATTTAAACAATCCCGTAGTAAAGATCAGATT ATTGATTATTT

ATTTGATAAGACAGATAATTATATGGATGAAGATAGAATATTATTGATGACAATGAT GAATAATTATA

CGGATGAAGATTTACTTAAGCTTTATTATAAAAATAACTTCATTGATTTATTAAAAG AATCTGATATTG

CAGATAATTATTTTAAAGAAATTCTAAGTTGCTATGAATTTACTGATCCAAACGATC CTCCTGCTAAAG

TTATCTCCACTAATGAAATTTGTACTATTAAAGGAAAAGATAACGGTAAAATTAAAG TTAAATTATCT

AATGGTGAAATTTCTCTAGAAGATCCTAGTAATATTTTAGATTATAGGGAAAAATTA GATAATTTATG

GAATATTATTAGAAATATTGTATTCTACAATTATCAAGATTTCTATCGTATGGAAAA TTCTGAAGAAAG

ATTAAGAAAAACAGTGCTCGTGGTTAATGTATAGCCACACTTATATAGTAATATATA GGTTAAAAATT

CTATTAATTGCTGGAAAATCCTAAAGCTTATTTAACTACAACGGAATCAGTAATGAT AAACGTGAATG

TTGTCGAAAGACTGAAAAAATAAATAAGATTAATACATGGTGAAATAAAAGTACTAT AATATATAGTA

TCCTAAATATTAATTATAATGGATGATCAGCAGCAGTATTTCTTTAAGATTATAAAT GAAAGAAAAAA

GAAATGTTGTTCAACGACTATCAAAAGATTATTATATAAATAATAATTTAGTAGAGT AGAGCCAAGCT

TTTGGGTTAGTATTTAAGAGATATTATCTTAATGTAAAACTATTAAATCGAAAAATA GAATTATCCTTT

AGTAAGGATAAAGATATAGTCTGTTCTTTAAGGAAATCTTAAAGAAGTTCATAAGAG AACTGCATAAG

AATTAGCGCACTTATGTGAACACGAAAGTGATACCGACTCAAACTTCTTGTATCTCA ATCACTTTGTCG

ATTTATTCTCAGAAATTTATCCAGATATTACGATGAAAGAAAATGATAAATCTATTG TATCTGCCATTA

ATACTATTATGTATATTGTTACTGAATGTATTAATGAAACGTATTACAAGTATGGAA TGGAACTCGGTA

TTCCAGAAGATAAACGTGGACTAATTAATATGAAGAATGAATTTCTATATAAACGTT TAATGCTAACA

GACGCTCAAAAGAATTATGCTGGCGTAATTTTAATGCAAGAAGGAAATATTCTTCAG ACTCCTAAGAT

TGATATTAAAGGATTAGCAATTAAGAAGACAAATACGAATAAACATGTACGTGAAGA ATTTTCAGGA

ATTCTTAAAGATGTCATTCTTGAATCAGATAAGATTGATGGTTCTGAATTTATTACT AGATATAAGAAT

CTAGAAAAAGAAATTCGAAGATCTTTAATGAATAGTGAAATCACATTTACTCTCCCT AGAACTGCAAA

TATTAAAGAAAACTACGTAGCACCATATACGCAAGCACCATACAAAGGTGTATTAGT ATGGAACACAT

TATATCCTGATAAAGAAATTAACTTACCAAACAAAGTTAATCTTATCAAGCTAAATA TTGAAACTTTTG

ATGATATTGAAAGTAAAACTAATGATCAAGATCTAATTGAACGATTTAAGAAAGTTT ATGAAGATGAG

GAATTGACAAAAAAAGGAATTACTTATATTGCTATTGAAGCAGAACAAAAACATATT CCTGAAGAAAT

CATTCCATTTATTGACATACCTGAAATGGTTAAGACTCATGTATCATCAGGATCCAA ACTAATGACGTC

ATTAGGATTCAATCCATTAGTAATTAATGGATCATTATTCCCAACAAATATTATTAA CTTTTAATGAAA

GTAGGAAATCTATTGGAAAATTTAAATATTGATATGAATGATCCAACCAAGAAAAAA CATATTGTGGT

AGATTGTGATGAAGTATTATGCAATATTTCACCAAAATGGACATACTTAATACATCA AGAAAAAGACT

ATTTTGGTAAATATATGAATCTTATTGATAATTTTGATATTGATCTGCATTATAATA TGGTTTTATCTAG

AAATAAGTTTTATCTAAATCAGTGGTTAATTAAAGATGAATCATATACGAATTATAG TGAAGACGAAA

TGGATGAAGTATTAAGACGTATGATGATGCTTTATGAAACTGAAGATTACTATGATA ACTTAAAACCA

AATCCTATTGTAGAGTCATTAGCATTATCGATTCGTCAACCTATTTTAGATAGAATA TCTATTGTAACA

AGAACAAACGCTAAAAATCTTAAGTCTAAAGAAAGATTTCTTAAGAATTGTTTTCAA GGTGTTATGAA

TAAAGTTGATATATACTTTGTAGAAAATGATGAAAATAAGTCTGATATTATTAAAGA CTTAGGTGACG GTATTGCAGCTATATATGAAGATGAAGTTAAAAATATTGTAGACATTTTAGATAACTGTA ATAATCTTG

ATAAAAGCTTAATATATGTACCTAGTTATGGATATAATAACGCTAACCTTGATTTAT ATACTAAAGCAG

AAGAAAAAGGAACTCAATTAAGATATTATTCATATTAAAGGATGTGGACTTATTATG TATAATGGTAA

TTATGATATAAGTCTATATGAATATTTAAAAAGTAAACTTAAAGTATGCTATATCAC AAGCAAAAAGG

ATGAAACTGTTATACGTTGTCCTTTTTGCGGTGATTCTGCAAAAAATCAGTATTCTG CACACTTATATA

TAAATAATAAACCACCTTATAAATATTATTGTCAAAAATGTAATTCAAATGGAATAT TTAATGATAAG

ATACTTAATAATCTAAATATTTTTGATGCAAAACTAAATCAACAACTTAAAGTATCA TACGAAAAATT

CATTAAAGATGCAGGAATAAAATATGGAAAATCATTTTCATCACTATTTAATATGGA TGAAACGGACA

TTCTTCCAAATAACTTTGGAATGTTAGAATTAAGAAAAATAAAATACTATGAAGATA GATTGGGAATA

AAACTCAATGATGAATTATTAATTAAGTATAGAATTATTCTTAATCTTAGTGATTAT ATGGAAAATAAT

AAAATTCCAATAAAACAAGACAAATGGTATATTGAAAAATTAAAAATGATTAATGAT AATTACATTAT

ATTCTTATCTAATGACAAGAATGTTATTAACTGCAGAAATATAACAAATGTTACTGA AAAAAAGAAAC

GTCATATTAAAATGAGACTATTTGAAGATTTTACTGATGAAAGTAGAAGTTTTTACT CAATAAAGAAT

AATATATCTCTTGATAAATCTTTATACAATATTCATTTAACAGAGGGTATATCTGAT ATTATATCCGTG

CATCATAATATATTTAAAGATCAGGAAAATAATAATGATATTTTTATATCTAGTAAT GGTAAGGGTTAT

AATTCGGTATTACAATATTTATTATCAATTGGGATTACAAACGCAAATATTAATATA TATGGTGATTCA

GATGTTAATCGTAATTATTATAATAGATTAAAGTATAATTTACTAGCTAAATATAAT GGGGTTAATCTC

TATTTTAATATTGCTAAGGATCCTTATGGTAATGGATTTAAAGACTTTGGCGTAAGA TCTGAAAATGTA

GAATTAAGTAAAAGCATTAAGATTTCTTTCTAACTTAATGGATCATAGAAATTTTCT AAAAAAAAAAA

AGACCCTAATAGATATTATATCTATTAGGGTTATATTTATTTAATTATTCTTTTTTT AATTGATAAGGAT

ACACATTAATATATTTACTATCTAATAAATCATACACATTAATTAACCGACCATACA TATTAATCTTTG

AAATTACCACATCGTGAATTTTTCCTAAAGAATCAATAATATAAAAATCTTTTCCTA CAATAATATTTC

TATTATAAATTTCTTTCATGAATTCATCTAATGAATTTTGGTCTAATTCAGTATTAT ACATATTAATCAT

TTATATTTCCTTCTTTCTTTTTTTTTTTTAATATATTTTCCATTTCATGATAAGGTA TATTCATTATAATTG

ATACATCATTAGTACTATAATTATCATCTAGATATTTATCTATTAATCTTTTTCTTT CAGAGATGCATTT

_{ATTTTTAGCAGTATAATGATCATACTGTCGGTTAGCACTTTTAAGTTCTTTAAAG AATAAACTATTATT}

GTTAATATATTTTTTAATATTAGATTTATCTACTGATAATTCATTAGCTAATGAATA AACACTGCTGAT

ATTCTTCTTATTGATAATATCAAGAATATATGATAAACGAGAAATTCTTTTAACTAT CAAATTGCAATC

TTTAACTTCCATATTAAAAATAATATCTACATATTTTTTCCATGATGGAGGATTATC GATAGATGTAGT

TTTATTATTTAATAGTGAATTAAGATATATGACAATATCTTTATTTAATTTGGTATT ATTTATGATATCA

TCATATTTTCCTTCATCATAATTACGTTCTATATATTTTGTAAGGTATTTTATTTTT TCATCATCAAGACT

AAAATATGTCATATATTTCTTAAAGAAAGTATTTAACTTTAATTTAGTATATCTTCT TCGAATATTAAA

ACCATAAACAAACACATTAGTTACTGTGGTATCTATATCTTCCATAACAGTATTAAC TTTAATATTATT

ATTAACAGTATTAACTTTAATATTATTATTCTTAATAAAATTATTCATGTTCTTTAT TTCATCGATAGTA

TTAATGATAATATTTCTAGACAATAATTCTTCTTTTTTAAAATTATTAATAACTTCT GTATTATTTAAAG

ATAAAATGAAGGCATTTTTCATCTTTTTAATATTATTTCTAATAACTTTATTAATTA TATTTATATCAAC

ACTATAAGTTTTTGATTTTATGTTATTAAATATATCTAGGTTAGTAATAATATCTTT TTTAGTAGATAAT TTTAGATAAGTGTTGATTATAAATTCATCTATATCTTTAGGATATATAATATACAATGCA TCAACCATA

ACCTTATTATCATAGATAAGTTTAATTTTAATTGATAATTCTTTTTCTAGAATATTA ATACAATTTTCAC

TAATTGATGTCTTAGTATTAATTTTTTTACCATAATGGTAGTCATTTCGTATATCAC ATATTATTGAATG

TTCTAGATTAGTAATTATATAAATTTTATTATATAATTCTTTATTATTCTTTATAAT ATTATTAACACTAT

AAATATAACCAACGCCAATATCATAAAATATATCCATATTTGTAACAAAAGAAAATT TCTTTTTTAACT

GATTATATGACTTGATAATATTCTTTTCAATACTATCAGTACTTCCATCATTAAATA TCAATTTATTATC

CTTTAGATATTCTTTAAATGAATCTAATATAGTATTATAGTTATCTAGATTCTTATT GAGTACTAAAGAT

ATAATATCAATGTCATTCATTTTTCGATAGTTCTTAATACTTTTGACAATACTTTTC TTTGTTGGAATTTT

TATATTGTTCTTTATATTTAATTCATTTATTGTATTAAATGGTATATTACAGTATAA TAATATATCATCT

AAACTTAAATTTTCAATAAAAATTAATTGAATAAATTCATTATAGTTGATGTAATTA TTTTTAACTTTAT

TTTCTTCAGTAATTCGTATTCCTTTTAACATGGAATAAAGCTTTGACTGATCATAAC TAAATCCTGATA

GTTCAGAGATTTCTTCTAAGGTTACTTTATTAGGATTAAGTTTATTAATATTATTTA GGATAATATTATC

AACAATCTTAGCTTCTGAGATATTTTTGTTCTTCTTATTATTTTTAGTTTTATTATC ATAACTAATTTTCA

_{TTTTTTTATCAAATAGACCGGATTCATCAATATATAGATTTACTACACCTACTGG AACTTTATATTTCAT}

ACATATTGACTTTAAATCAAAATTATCATTAAGATATGTACTATCTATTTCATGTTT TAATTCCTCGCTA

ATTCTTAACATCTAGTTATTCCACCTTTTAAATATTATTAAAGAAAAGGATAATGAA AATAAATTTCAT

TATCCATATAATTACAATGCAATAATCAAGTTTGTTTTAGCTCTAGTAATTCCAGTG TATAATTGTTGA

TGATATATGCTCTTATTATATATTTCATCAAACAGTAATACATTATCATATTCCGAT CCCTGTGATTTAT

ATACGGTTGTTGCATAACCAAACTTAAACTTATTAATGATAACATGTGATTCTTCAA AAATATTTCTTC

GAAGAATTAATGACTTATACATTTCATTTTCATAAATTTGATCATCATTAGTTATTC CATCCGTAAAAT

ATAATGCATCTACATGCAATCTATTATAGATTCCAGTATCTGATGAAAATGTAGGTT TAAAGTCTAATT

CAAAAGTATCCAACCTTTTCTTATATTCATAGATATTTTCCACATAACCGATAATAC CATTTGTTAAAT

ACTGTTGTGATCCATTATCTTCATACATTTCTAACCAGTTATTCTTAAGACATATTA ATTTTTCACCAAC

ATATGGAAATGGTGAATTCAAATTAAGTATATTTTTTCTAATAAGAGAGTTTATCCT ATCAACAGTTAT

_{ATTTTTTGAAGCTAGAATTTGATCTGCGCCAGTATACATATCATAGTCTACATCT TTTTTATTAATAATC}

ATTACATTTTCACCGATAGGACCAATTCTTAATCTATTTTTCTTACGAACTTCATTA GCTAACCATATAA

TTGGATTATCCAGTGCTTGCCTTAATGGTTCATCTAGGAAGATATCTGGTCTTTTCA TATATTTATTAAT

TCCACCTTTAACTGGTGGAAGCTGCATCGGGTCTCCAATCATAATGATTGGGACGTT AAATGTAATTAG

TTCTTCAATCATTGAATCTGTAACCATACTACCTTCGTCTACAATAATTAATTTAAT ATTTTTTGAAATA

CTTTCTTTTTTAATAAAGTTAAACTTATTCTTTTTTTCATCATAAACTACATTATAC ATTAACCTATGAA

TTGTTGAAGTGTTATTATTCCCTTTCCTATTAAGAACATTAGTAGCGGTTCCAGTAT ATGCAGAATATA

CTACCTGTTCATCGTTTAAATTGATTGCCGAAGTTATAAATTTTATAATTGTACTTT TACCTGTTCCGGC

TAATCCTGCTATTGTAAAAACTTTTTTAATATCTTTATTCCACCATTCAACTGCTCG CATAACAACCTCT

TCTTGTTTGTTTGTTAGCGTAATAATACTCATTATATACACCGCTTTCTATCCATTT TATTTACTATAATT

TTTTATTAACATTATAAATTACTTTTTCATTAATATAATATATAATTAAAAATTTAT ACAACTTTCTAAC

ATAACATTATAATAGTAAATAATGGCGGTGATAAAATGTCAATGAGAGATATGAATG GAAATCGTATT

ATGGACTCATTTAGCTTCGATAAAGAGTATGAAGGAATAGTATTAGATAATAACGAT TTTGACGATAA ACTATTTATTAAAGTATATATCTCTGAATTGTTTATTAATGATATTCCTGAGAAGGTTAT CGATATTAAT

GAAAATATTGATCATACTAAAATAATTAATAATAATAAAATAAATTTTAAAAAATCT GTAGTACATAA

TAATTATTTGAAGTGCTATCCAATCATATATAATAATATGAATCTTGATATAATGAA ACCAAAAATAG

GTTCAAAAGTTATTGTCAAATTTATTAATGGTAATCCAAAATTGCCATATTATGAGA ATAAAGGATATT

ATACAGATATTATTATACCAATTCCTCCCGAAATTATAGATCCTCCTACTGATCCAT CCACTAGTGATG

ATTATACTTCTTTTGGATACTATAGAATGATTAAACTTACTAATCCGGCTATGATTG GTCGAGATATAC

TAAAAATCCAAAAGAAATTAAAGACTCTTGGGTATACATTCACTATTGATACACTAG ACGGTATATAT

GATTTAAGAATGTTGAATTATATAAAAGATTTTCAATCTAAAAATAAACTAAGTGTA GATGGACAGAT

TGGTCCAATTACGTTTAGAACAATTATGCGTAAAAATATATAATTTTTAAATTCGAA CATATATTTATA

GTAAGATAGTTTACTATAAATATATTTAATTGGGGTGGAAATTTTTATGGAACAAGT AACTTCTGGACT

ATTAATTTTGACAGTATTATCCGTAGTAATTCAGTATTTAGTTGAAAGAATTAAAGA TATTTTTCCAAC

AAAAGTTATGGATAAACTAGCAAACTATGTTAATCCTGCTTTCTGGTCTTTAATTGT ATCTCTTCCTATT

GCTTTTGGTATAAATATTGATTTATTTGCAATTATCGGTTATAATATGCATCCAACA TGGCTTGCAACA

TTATTTACTGGTTTTGCATTGAGTGGTGGAGCAACTGGTATTAATGAACTTATTAAA TCATTAAGTGCT

GTTAAAACTAATAATTTTACTCAAGCAGATTCGGTAAAAAATACTGATGAAGAAGAA ATTAAAGTTGT

CGCTAAATCTAAAAAATAATATATATCCCTATAGTGTATAATTGCACTATAGGGAAT TTTATTTACTAA

AATTATAAAATACATAATAAAATAACATTAAAATATATTTACATTAATATACAGAAA TGGATGATTAA

ATATGAAATATCCGATACGTGAGGATCATAGAAAAAGAGTCAAGACAAATTACATTA TTATTACTCAT

GCTAATAATCTTATAAAAAGGGGAACACATATAAATAATGCGTTAAGGCAGAGAACT TTTAAATACAC

TTGGGGAATATGGCAAGAATATTTAATGACTCACGTTAATAAAAGATATTTACCAAT GCATTATTTTAT

TGAATTAATTGATAAAGATTATGCAGTATTGAAGGGTCTTTCTGACCATAAACCTTC TTACTTTATTAA

TGATTTAGTAGACGAAGGTGTAATAAAATATGTTTACCGAGATTCGATATTAATAGT CATTGGAGATA

ATTTTAGTATAAATAATCCTGATACTAGAATGATTGATCATTTAGCAACTAAAGTTA TTCTTCCATTAA

TGAAAACGTATAATTTAAGTTGGAATAAAATACAATTTTTTGATGAGTGTTTAACTG ACTCATTTATTA

ATAATATTGATAATGATGAAATAAAATATAATTACGAATATGAACCAATGTCTATGT TTGATATGAGT

ATTCTAAGAAATGCAGTACTTAGATATAAATCATAAATATAAAATAATAATTATAAG TATTGTGTGGT

GATAATTGGAAATGGATAATAATCAAAGACATAAGAATAGAAATTTTTTTAATATAA TGATAATTATA

AATATTGTAATTATTGTTATAATAATTGTATCTTCAGTATATCTATATATACATATA AATTCAGGAAAC

AGTTATTCAAAAGAAACATATGCTAAAGTGAATAATGTGTATATGACATATGATAAT GAAGATAAGGA

TATACAAGTAAGAATTGGTAAAAAGAAACTAATAATATTTAATAATGGTAAAATTAA AGAGATTATAT

TTAATAATTTTGAAGTATCAGTATATGATGAATATACTTTAATATACATTTCTGGAG ATAATGATGAAG

TTAGTATTTCTGTAGACAATGATAAAGATTCCATTTCTGATATAGTCATAAATAATC AAAGTTTAATAG

AATAATTATATAGATATATAGAAGTGTGGAAAGAAGGTTACAATATATGCTCATATT AAAAATGAGAA

CTGACAAAAAAGTAGACTATAAAAAATTATGGTTTATAAAACTTCATAGAAAATTAA ATATTGAAATT

CATTATAATATAGAGGAAAATGGATTCTACTATATTGATAATAATAAAACATTAAAA CTTAAAAAAGA

TTTTTCAAGAACAATTAGTATGATTCTTGATATTAAGAAAAGATTCAATTCGTTTAA TACTGAAATGGA

TATAATTGATAATAATATTAATATGTATCTTAATGACGTTATAAATAACTTTGAAAA AGAAGAAATGC TAAGAATTATACTAGGAACTTCGGAATATAATGTGAAGAATCTATATAATGATCTTACTG AATTAGGA

ATTAATATTGATCCAGACTTATTATATGTAAATTTATATAAAAATACAAAACATTCC GAATATAATGAT

GAAATAAAGAATACATTTAAAAGAATTTGATAACCTGAATACTAATAATTAAAATAG TATTCAGGTTA

TCAATTTTTATCGAGCAAAAAATATTTTTTTCCTTCTTGAATGTTTTAAGGCACCAA TGCGCATTTTTTC

AACTAGTTCTTCTTTCTTATTTTTTCCATCAGCTAGATCTTCAATAAATAATTCTAT ACTGCCATACGTT

GTTTGAATATTTTGAAAGCGATGTCTAATTTGATATAATGATTCTTGAGTATCATAT AGACATAATTGC

ATAAAATGTTCTTGAAGATTTACTGGTATGCTGTCAAAATGTTCACTATGAACTGCG TTTGCATATACT

AGAATTCCGTTTAATGTATATTGGGGAGCAATTTCAATTTGGTTTGGATGAATAAAC CGGAATGTTGA

AGGATTTATTTGACCTTGAATGTTACTCATCATCTGATTTTCAAATAAACTTCCAGA ACCAGAACCAGC

TCTAGGAGTTCCTCCGATAATTGCACTATTACTACTATACATATCTAATCCAATTAC ACGATTAATATT

TAATACGGAAGTCTCTGTATCTAAATAATAACGATTCTCATATCCCGGAACAAGATC TTTATTAAATAC

TCGGATTTCTTCAATTCTTGGGAAATACTTACTAAACGTAATCAAACTTTCTGATCT TATTCCACTAAG

AATTTCTTCATGAGAAAGTTCTAATTGTGTAAATTTATATCCTAATTTTCGTTCTAA GAATCGAATAAC

CTCTGTAGGATTAATCATTTAGTTATCACTATCCTTCCAATAATAAAAATACAATAC CACTTCCTAAAT

TTAATTAAGAAGTGGTATATTTTAAAACATATCTTGTATATATTTGCTTAAATCACG TTTAATTTCTTCT

TCGAGATAAATCCGGATAGTTTCGTTTGATTGTTTAATACTTAATGTTTGATCTTCA GTAAGAGTTACT

GAACCATTCTCGAGATTCATAGATATACCTAATGATTCTGCTAATGAATATACATTT TCAGATTTTTTA

GTAACAAACTCTAATAATTCAGAAACTTGATAAGGAACTACTTTACCTGAAAGATTA TATGAGTTTGA

GCTTGCTGCTTCTAACAATCCTTGATAATCTTCTGAGAAGTCTTCATTAATCCGGTG AGTCATATATGA

GTTTGGATGGGATGGAATAACAACCCAATCATAGCAGCAAATCATTAAAGGTGAATG AACTCGTTGAT

ACTTCCCATCAGGCTTAATAATATTACCAATACCACGCATGGAGAATGCTGCCTTTG ATCCTTGATTAA

TCAAACCTTTCATGTCTCTACCTACAGATGTATCTGCAGTTTCAACTCGTCCAATTA ATCGATTCCCATC

AAACTTAGCTTCAGTTACAATATGCGAAATATTGCGTTGATCAATATATAATTGTCT ACGATTATCAGT

ATTTAATGGATGACCTGCTTCTCCAAAGAATGTTCTATTTTTAATTTTTTCCTGAAC AATTGGGTTTTGT

ATTGCTTCATCAATTGCACGTCTATCATAAATACGGTTATTACGGTTAGGTGCATCA GCTTCTTGCAAC

TCAGTCTCGAATAATACATTATTAAGTGTTTTATCTATAATTTTCGGTTTAGATTCA GTGACCGATTCCA

TTATAATATAACCTTTTTCTTCAGTCATAATAGTAATACACGTCCTTTCTTAGTATA TAAATAAAATTTA

TAATAAAATGTTTGATTAGATAATTATTTTTTTAAACAACTTATTATAAAATATTCT TTTTATCATTTTT

GATAAAATATGTTTTAAATTTAAAGAATATTAAATTATAAAATAAAATGATAAGGTG GGAAATATAAA

ATGCCAAAAACTTTTTTAGATGTAATCCTTGAAGATGCAGACGCATTTGAAGCTAGT AAATCTGTTGA

AGTGGTTGATAAAAATACTACTGAACCTGAAGTAGTCGCTAAAGATGAAAAAGCTGA TGTAGAAGAA

CAAAAAGAAGTATGTGACGAAAAAGAAAAAGCTATTGAAAAAGAAAAAGAAGAATAT ACTAATGAT

GCAGAAGTTGAAATTACTAGTGACGTTTCATTAATGAATAATGTTGCTGATAAATTA GATAGTGGTAT

GTCTATTGAAGAATCATTCAATTCTCTAATCGAGGTTAATCTAGTTAAGAATGAATT TAAAAACATGG

GCTTGACTTCTGAAGAAATTAATCTTCTTGCTGAAGATGCTTCTAAAGAAAGAAAAG GAATTATACGT

GGATTGGCTAAAAAAATCGGTATCGATGATAGCGGTAATGTTGATGCTCGTAAATAT GTTAATGCTCG

TAAAAAATTAGGCGTAAAACAAATTACTGCCGCAGTAACTTCTACGGTTGCTGCAAG TGCTGCTGCTG GAGCTAGTAGCTATTATATTGAAACATCAAAAAGTAAAAGCGAAACTGTTAAAGGTGGAA TCTTTTCA

GGTTTAACTGTAGGATTGGTCGTAGGTTATTGGGTTTCCCTTTTCTCATTTGTAGTT ACTATTTTGCAAA

GTGCTAAAGTTAAAGGTCAAATGAAAAGTGATCCATCTATCTTAAGAAATGCTCTTG CTGAAAATAAA

AAAGATTTAGCTGAAGTTGTATCTTCTATGTCTAAAGTTAAAGAAGATGCTAAAGCA ACCAAGCAATT

AGAACGTATTCAAAAAGCTTTACTTCGTGAAAAATCCAAATTATTGAAATTGCAAGA AAAATTAAATA

CAAAATAAGTTATATATGATCTCAATTCTGATTAATTTCAGAATTGAGATTTATTTA AACATTATTATA

TAAGAAAATATATATTGGTGGTGATTTCAATTGCATCTTGATGAGGAAAGTATTAGA TACGCTATAAA

ATTTACAGAATCTTTAGAAAAAAATGATTTTGAATATGGTCAAACAATTCGTGAAGA AATTCAAAATG

AAAATAATTCATCTCAAATAAAAAATATTATGAATATGCTCAATATTAAAAATCCAA ATACTATTACT

GTTGAAGAATATTTAAAGATACGTAGAAAAATTAAATTTTCGGGTCTTATTGGATTC TTAGCAGGTCTC

GGAGGAAGCGTAATGTTTACTTCAGATATTATTATAAATAATGATCGGCTTAGAGAC GATCCTCAAAA

TAGAGGAGTCGCTAATAGAAATAATCGTAGTAAGCTAAGTATGCTTAAGTCAACCTT ATTTGCTTTAGT

TTCGGCTTTTGGTTCATTTGCTTTATCAGTATTATATAGTAAGAGCGTTAAGAAAAC TTCAGTAGCTAA

TCCATCAATAGTTAGAAGTTTATTAGCTATTAATGCAAATGACTTAAGAATGGTAGA AAAAGCAAATA

ATAGTGTAGTTACTAAGTCTGACTTAAAATATATACGTAGAATAGAACGAATATTAA TTAGGGAAAAA

AGGGATCTATTAAAATTGCAAGCATACGTTATAAAGAAAAATAAATGAAAGAAGTGA AAATTTTTATG

GAATATAATGATGTATTTTTAGAATATTTAAATTCTGAAGAAGATAATATTGAAAAT ATGGAAGAATT

CCTATCAAGCTACATTGGAATTAAACCAAGATATCTTGAAATTAGACCTACTGTATT TAGTGAAACAA

GAATTACTAATGATGGTATTAGTGATGAAGAAGATAATAGCGAAGAATCTGATCGTA AAAGATCTACT

GATGAAGTAAAAAAGATTAGTAGAGAAGTAATGGAAAAAGATAAGAAAAAGAATCTT AATCCACAA

AATAAAGCAAAAATTGCAACTATTAAACGTGAAATGGAAAAATCGATTAAAATGGAT CCAAATAGTC

TTGGTAATGATACTAAACTTAAAAGACTTATGCGTGTAGGAATTACAATGTTAGTTT CTTTCGGGATTA

TTTTTGCTCCTGCAGTTGGTGTCTTAATAAAGATTATTGCTCTTATCGGAGTAGCTG CTACTGCAAAAC

ACGTTAATCGTAAAAAATTGGAAAATACTATTATATTACTAATGGATAAAATTAAAT ATATTGAAGAT

GAAATGGAAAAAGCATCAGACAATCCTAAAAAGAAATATGAATTAACAAGAGTAAAA CGAGAACTCC

AAAGAACACTTATGAAGTATCAGTCTAGACTTCGGAATTTCCATTAATATATGATTT GTATAAGCGATG

TTGCAAAGGAGGTACTATTATATTGAAAGATGATTTCTTTAATTATTTATTTGAAGC AGATGATCCAGA

AGAAATAAGTAATATTGATCCTAATGAAGATAATACTGAAAATAATAACGAGGATAC TCCTTCTAATG

AAGAAAGTTTACCAAACGAAAATAGTGATGAAAATGATTTAGAAAAGGATCCAGAAA TAGAAGAACC

TGATAATGAAGAAGAAATAGAACCTAATGAAAATGAAGACCCGAATAATAATTTACG TATAAAGGAA

ATATTATTTGAGAATTTCTCTGGACTTAAAAATGCAATTAAACGATTATTTACTGAC ATTGAATCGGTA

ATACATATCGTAAAATCATATGATTCTAATAATGATAATCATAATTTAGAAAATACT GTGGATGGAAT

ATCTGAAAAAGGATATGACATTTTAAATAAAATTCAAACATTACAAAATGGTGTAAT TCTTAATATAT

CAAACGATAAATTAAAAATCATATATAATGAATTAGAAAATCAAGTAAGTGATATTA TTAAGGAATAT

TCAAATAAAGTTGATGTAAAGTTGAAAAACAAGTATTAATAATATAAACAATTTAAT ATAAAAATTTT

AATTTATTTCTATGTAAGTTTCGTTTATTACTTTTTTAAAGTAAGAATGATGAACAA TTATATATAAATA

ATTTATAATATTATTTTTATAATCTATAATTTTATATAAGAAAAGGAGAGAAATTAA ATTATGCGTAAT TTTAAACGTATTACAAAGACTAATACAGATTCTTTTAGTACTCATCTAAGCGAAACTCAA GACTATTTC

GCTAATACTAAAGGAACAAATATTACTGGACAAGATATCGCTGCAATTATAGTGAAT GAACAATATTT

TGATGAGTATGCAACTCGTCTATTAGAAGGTTTCGATGCTGACCTTAGTGAAGAACT AGGTGTTCTTTT

AGAAAACACTCGTAGCAACATTATGGAATCCTTGGGTGGAATTACTCCATTTGCTTC ACTTTCAATGCC

TGTTTTGGTTAAACTTTGGGCTCGTTTGTCTATGGTAAATGCTATTCCTACTACTCC TGTTACTACTCCT

GCATTTGTAGTACCAACTATCAAACCATATACTATTGGTCCAGATGGTGAAAAATAC TACCTACCAGA

AGCTATTAATACTATTCCTGAACACTTTGTAAGTCTTCGTCAACTTAAAGAAGATAT CACTATTACTGG

TGGTCGTCTTTCTGACTATGATCTATTTACAGGTGTATCAACTGCTGACCGTGCTAA AGGTGATCAAGT

AGACCGTAAATTCCAAATTGTTGCAGGAACATGGTCTGATTCTTATAATGTCGCTGA TGCTGCTCTTGG

CGAATATGAACTTAAAGGTCAAGCTCTTAAAATGGATATTCATGGTAATATCTTTGG TAAAGTAACAT

ATACTACTGATGGTAATGGTGCTACTAATGAAGATACTATTATGGGACATGTTGATG TTGAAAAAGGT

CGTTTAGATTTAACTTCTCTTTCTGGTAAATTGACTGAGTTCAAAATTCAAGGTTTC GTTTCTTCTGAAA

TGCATACTGGTACAACTCAAGTTGGTTTTGATGTTGATGATCGTACAATCAACATTG GTACTGCTCCAC

ATATCGAAGGTATCCTACCTATCGAATCCGTACAAGATAGTAAAGCTATGTATGATA TTGATGCAGCA

GCTGTTATTGTTGATACAATGTCTGCTACTTCTGCACAAAAAGTTGATACTGACTTG ATTGAATTCTTG

TTACGTTCTTATGAAGGTACTAATGCTGCTTATCATAAAACTTTCGATGTACATCCA AATGGTGGATAC

AACATGCATCCGCATGAATGGCGCCGTGGTATTCGTGACGTTATTGACTGGATGTCT CAAGCAATGAA

AAATGATTACAAAACTTATGATGCTTACTTTGTAATTGTTGGTAATCCAATTGACAC TCAATTGATTCC

TGACATTGAATGGGAATTCCAAGGAGCTACTGATGAAGTTGCGGGAATTAACGTTTC TTATAGCGTTG

GTGCTTCTTCTACAGTTAACCGTTATAAAGTTGTTTCTTCTGACTTAGTACCTGCTG GAGATCTATTAAT

CTTTGCAGTTCCTACTCGTGAAGACTTCAAAACTTACGAATACTACCCATACACTTT CAATATCGTTAA

TAATTACAACAATGCTGTTAACCAAAGCGTTCCTAACATTATGCTTTCTCGCCGTTA TACAGTTGAAGA

ATTTGTTCCAATTATCGGTAAAGTTACAATTAAAAACAACGATGCAACTCAATACGC TCGTTAAATAG

AGTATAAATTCTATTCAGTTTCGTATATTAATACTAGTAGATAGGAGGTGTTTCGAA TGGTCTTCACAC

TCGAAGATTTCGTTGGGGACTGGCGACAGACAGCCGGCTACAACCTGGACCAAGTCC TTGAACAGGG

AGGTGTGTCCAGTTTGTTTCAGAATCTCGGGGTGTCCGTAACTCCGATCCAAAGGAT TGTCCTGAGCGG

TGAAAATGGGCTGAAGATCGACATCCATGTCATCATCCCGTATGAAGGTCTGAGCGG CGACCAAATGG

GCCAGATCGAAAAAATTTTTAAGGTGGTGTACCCTGTGGATGATCATCACTTTAAGG TGATCCTGCACT

ATGGCACACTGGTAATCGACGGGGTTACGCCGAACATGATCGACTATTTCGGACGGC CGTATGAAGGC

ATCGCCGTGTTCGACGGCAAAAAGATCACTGTAACAGGGACCCTGTGGAACGGCAAC AAAATTATCG

ACGAGCGCCTGATCAACCCCGACGGCTCCCTGCTGTTCCGAGTAACCATCAACGGAG TGACCGGCTGG

CGGCTGTGCGAACGCATTCTGGCGTAATAAATATTATGAACCTTTCAGAGACCTTTT GGTTTCTGAAAG

GTTATTATTTATAAAAATTTAAATTGGCGGTGCAACCATGCATATTGATTATGGTAT TGAAAAGAATAT

ATCAAAGTACTTACATGAAGAATTACTAACTGAAGATATCTATAATCATCCTTTATT AAAAAAGATTG

ATGATGAATTTCAGAAAATATTAGATGAAGATAATATTAATGATACTAAACTACCAG TAACATCATAT

AAAAAAATTCAAAATATAATTAAATATGTCTCAACTATATTTAATATAAATTTAATT ATAACGATTGAT

AACGATAATATCCTTACTTATGGAATGATGACATTTATTCCGGTTAAAAATCTAACA AAGATATCTAAT AATATAAAGAAGATTGTACTTCAACCAAAAACTGGTTTTGAATATATTAAAACTGAAGTT ATTGAAAT

TAAAATACAGAAAAAATTAATATCTTTCATTAAGGATCCAAACTTACTTATAAGAAA TAATAAAGTTC

CAAAAAATTATACTCCTAGTGGAAGAATATTGACCAGTATACTTCTTCATGAAGTAG GTCATCATATAT

TCATTGGATTTGAAATTAAGAAATCTATTAAAAATGATAAACTTTTTTCAATTAACG GTGGTAATGGTA

AAGAAATAACTATACCTAGTAATGTTAATAATAATAAATATGTATTAACAAGCACTA TATTATCTATAT

TAACGTTAAGTATTTCTATGCATAGTTATATGAGAAGTGAATACAATGCGGATAACC TACCAATACAA

TATGGTTATGGTAAAGAAGTATTTTATTTTTCAGAATTAATGGAAATATTAGAAAAA CAAAAAAGAAA

TTCAATTCTATTAAAGATTAAAGGATTTCTAATGTTTGGTAAAGATAATTATTATAA TCGTAAAATAAA

GAATCAAGTAATTATTATGATGAAAAAAGAATTAAATAATGATAATAATAGTCCTAA AGATAAGGAA

ATTATTATAGATAATTTAAAAACTATAGAAAATCTTGAATAGATAATGTGGTATAAC TTATTAATTAAT

AAGTTATACCATTAATACGCAAGTAACTATTAATTATAATAAAATAAAGAAATTGTG GTGATAAAAGT

ATGCTTAAGATTAATATTAAAGATAATCCTGAACTTAAAAAGAATATTACTTCAAAA AATAAAAAACT

CTTTTATGATTTCAATACAAATAATCAATCTTTCCTAGAATTAGCTATTGAATTAAA AAGATTGGGAAT

CAGAAATAATAAGTTACATTTAGTTTTATATGATAAGAGTCTTTCCGGAGTAGATCC GTATGACCCGA

ACTTAACTGATAACGTAAAGGCAAGAATTGTTAAAGAGAGCATTATTAATTTTTGGT ACTTTATTAGG

GAAGTAGTTCGTATTCCAGTTCCAGGATCTTCAGTCCATTTTGCTATTCATAGAGGG AACCTTGCAATG

TGTTTCTGTTTATTAAATAATTTAAATACCGTATTAATGTTACCTCGACAACATTAT AAGACATATAGT

GCTGTAGGTTTTTATTTATGGATTGAATTATTAGTAGGTAGAAACTATCAAATGATC TTTTCACATAAA

TCATTAACGGATAGTATTGCCAATCTAAAAAGATTGACGGCTCTATTTGAACTATTA CCGACATATATG

ACTGAACCTATCTTAAATAGTAAGAATGATAAGAATGCTGAAACTATTTTAACAATT GACTCAATAAA

TAATACCATTAGGACAATTGGTCCAAGCACAGATATTGCTTCAGCAGATAAGTCAGG TTAACTTAATT

TTTCGGCTTGACTATAAAACTTTTTTAATTGCTGGAACATCCTTAAGTCTATTAAAC TACAACGTAACT

GGTAACGGTAAGCGTGAATGTTTGAAAATTAATAGAATTGGACAATCAGCAGCCAAG CTTCCAATGAT

TATTGGATGAAGGTTCAACGACTATCGAAAGGGTAAATTTATATTTTAAATTTAGAA CTGAGTAGAGT

AGAGCCAAGACAAAAATTTGCAAGTTTACTTGGTTAGTAATTAAGTGACATTAACTT AATGTAATTCT

ATTAAATCGAAACGGAAAGTATAGAATAAAAATAAATATATATTATAATAATGATGA GATAATTTATA

TCTTCTTTAATTAAGATTATTAAAGAGGTGATTATTATGGTAAGAAAAAACACAGAA TTTGATCTAGTT

AATAGAATATCACAAAAATTCAGTAATAATGAATTTACCTATATTGAAGGGTTTAAT AGAATGATAGA

TAAATGTAGATTTAAATGTAATAATTGTGGAAATGATAATTATTATACTTCGCCATC CATATTATTGGA

TAAAAATAAATCTATATACTGTAATCTATGTAATCCTGCAACTTTACGAAAAAATTC ATTTATGGATAA

TGTTAATAAAAATTACACTGTTTTAGAAAAACCTAAAAATAATAAACAAAATATATC TGTAAAGTGTA

ATTTATGTGATTTCATATTTAAAACAAGGTCACAATATTTAACAGCTATGGACAAAC CTAGTAAAACTC

GAAATTTGTGTCCTAAATGTAATGCATCAAATTCTGAAAAAATATTTGCAAAATTTC TTGATTCTCAAA

ATATTAATTATGAAATGCAGAAAAAGTTTAAAGAATGTATCGGTATTAATAATAGAG TCACTCCATTT

GATTTTTATATAGATTCAATGAATCTAATTGTTGAAATTGATGGAAAACAACACGAT TCATTAAAATAT

GCATTCCATAGAGATATTAAAGAATATGAAAGAACTGTTGCTAATGACAATATTAAA AATAATTTTTG

TAGTGAAAATAATATTGGATTAATACGTTTAAGATATAATTGCAAAAGTAAAGAAAT TGAATTCATGG AATCAATTATTGATGCAAAATATATTCCAAACGTAAAATTATCCATAAATGCAAATCTTA TTAAATATT

AGATATAAATCTCATCAATTTATAATTCTGACTCTTCAAATAAAATTTGGAGAGTTT ATTTTTTTTTTTT

TTCTATAAAGATATAGTCTATGGGGAGAGAAATCTCTTAAACTTGTTATATTCTAAG CGAGGAATGAC

CGTTGTATGCGCCGTAATGAGTTTATAAAAACTCTAATCAATTTTGAGAATAACGGA ATGATAGATAG

CAAATAATCTTGAAACGTTATATCTAATACTCCTACATGCATATATTTATTAAACGG ACTATATGTGTG

AAGTTAGGTGAAGTCAGTTGAACCACTCCCCTATAACGGGAAACTTAAGTATTATAT ACTAAGAGTGT

ATAGACTGGGATGCGTTATAATATGGTAAGGATATTCTTTAAAAGAATTAGACGAAT CAATGAATTAA

AACCGTTAAAAATTAATCTAACAGGTTAATGAATACTAATAGGGATGAGTAAGTGAG CGGTTATGAAA

ATCCTATTTAAGTTATGCTCTTAAATTATTATTAGTGCGGTAGAGTTGGTACCTAAG TTATAACTATGC

TATCAAAATTGAAAAGGTGGAAACTAGGAAGATCGTAAAGATGTTTAATGTCTGATC TAATAAATAGG

AAATGATTTATGAATCTTAGTGGCAGCAGCCTGTAGTAGTGATGAAGCTCTTGTAAT GAGAGTGGAGT

GAAGGGGCATAGTCAGAGATTATATTAACCAAATAATCTTTGATGGAACGCTGTATA CGATGAAAGTC

GTACGTACAGTGTGAAGTGGGGGAAAATCCGGAGATAATTTCAAAGGATTACCTATC ACTATCCGTTA

ATATGGTTAGATGAATATGCGTTTTTAAAATATAATGATACGGTATTTAAAGCAATG CGCCCTGCTTTT

ACAGAAGCAAGTAAAGCTGCAAGCATGAATGATACTCCGTATTCAATACTTATTACA ACAACGCCTAG

TAATTTAGATTCCGATGAAGGAAATTCATGTTATAATCTTATACAAAATGCAGCTAG GTTTGATGAAA

AGATGTATGATTGGTACTATCAGTTTGGTCCAGAATACCTTCAATCATACTTGGATA AAAACTCTGGTA

ATGATTTTATATATATTGAATTTAGTTATAAAGAATTAGGTAAAGATGATGAATGGT TAGAGAGTCAG

ATTCGGGCAATGTTAGGTGATAGACTTAAGGTTAAGATTGAATTATTATTAGAATGG GTTTCTAGTAGT

GAAGATTCAATCTTTAGTGAAGATATTATTGAATCTCTTGAAGGTAATATTATAAAA AGGGAAAATTA

TGCAGGATCCATATATTTATGTGATGGAACATATAAACTAGATGTTATTAAAAATCC TATAAACTTATT

AACTAAAACATACGTTATATCAATAGATATTGCCGGAGGATTAGGTAAAGATAATAC CGTTGTAACCG

TTATTGATCCAGTAGACCTTAATACGGTAATGGTATTTCAAAATAATAAAATTACTG TTCCGGAATTAG

AAGATCTTGTTACTGATCTAGTGTTAAATTATATTCCAAACGCAGTAGTTATTCCAG AACGAAACTATG

GTGGGGAACAACTGATTGATTATATTATTAAACATAATTTAATATCTAAAAATCTTT TTTATGTAACAA

AACAAATAACTACTGAAAAGACAATCTTACAAGAAAATAATGTTTTTAGAAAAAGAA GTAATAAAGT

TAGAAAAGAAAAAAGGGTATATGGTATATATACAACAACTAAGACTCGTGATATAAT GATTAATACTA

TCCTTCCAATGATTGTTTATGAAAGACCCGAATTGGTAAATAATGCTTCCTTATTTA ATGATATTAAAA

CGCTAGAAAGAAAAAGAAATGGTAAGATTGAACATAAGTCAAATCGCCATGATGATA ATTTATTTTCA

TATCTGGTAGGATTATATGCACTATTATATGAACACTCGATCAGTAGGTTTGTGGAT ATTATTGATAAA

CCCGAGTTAAATAAGGAAGATGAATTAGTTGATAGCGGTAATAATACGGGTCAACAT CGTTTAACTAG

TTCTCAAAAAGCATCAAGAACTATTAATAATTTAAGAAAAGTTAGTAAAAAACCAAC AAGCAAATCA

ATTATTAATGCATCAATGAATATAAATAACGAAGATTCTAGTATTAATAATTCTATG AGTAAAAAACC

ACGAAGAGGACTAAATTTAGTCCGAAAATATAATAAAAAATAAATTAATTTTTTATA TACTATCCTAA

AAAATATTATATAATAATTAAATATAATTGATTGGAAGTGGAAATTTTATTATGGTT ATGTTAAATGCA

ACTGTAAATGAAGAATATAAACGTGAAAACGTAAATGAAATTATTACAAATATTAGT GAGGATATTAT

GATTGATAATATCTTATCTCAAATAAATGATACTGATATTCAGGATCTTTCTGAAGT AAGAAAATCATT CTTTGAATACTTTGAAGAACGTTATAACTTTGTTAAGAAAAATTATAACGATGATGATGA AGCAATGC

AAAATTGCCGAGAAGTCTTTGATGATATTTTAAATCAAATTATTAAAGCAATCTCTG AAAAATACAGT

TTTGATCTTTTCTTTTCAGATATCCTATTATTCGATACAAAAGTAGAAATTACTAAA AGTCTATATTATT

TCTTTGTCATCAATATTCGGGAAAATATTGAAAATATGATTTATTATTTTATCATGA AAAATAGAAAAA

CATTAGTAAAAATGTTTAACACTATTAGTAAAGAAGAAAGAAAGAATTTAAGCTATA TTAATCTTAGT

TCTGCAATCAATAATGATTATACGACAATGATATATCATTTAAGCATGATTATTGAT AATATTGAAATT

CCTACTAATGAAGATATTATTGAATTAATGGTTGAAGATAATTCATATGAACTTTAT AACTACGTAACT

GTTAATACATTAGTTCTTACAAATTTCTGCGAAGTAAATTATAATGAAAACTTTTAC TCAATCTTTCTA

GATATTATTAAGAATTCTCCAATTATTGTAAGAAATGTTAGAAACTCACTTATTGAC TCATTAAAATAA

TATTAATTACCCTATCCTTAAATAATTTAAGGATAGGGTTTTATTTAAACAATTTTT TATAAGAAATATT

TAAAGAAGGGAGACGTTAATGGTTGACTAAAAAGATGAGCAGTTTAGACCGAATTAA AGATTCACTT

_{ATTTTTAAAGGTGAAATATTAGATATATACTTACCAAAATCTAATTTTGATAAAA ATCTATCAACGTAT}

AATGGTGAATATATAAATACTATGGGTATCTTTTCATTCATTGAAAAGAAAGCTGGA CCTGAAGATAA

AACAACTAAAGGAACTTTACGTAAACTAGAATTACCTAATATGATTGACTTTCAATA CGATTCAAGTT

ATTCTTTTAAGGGAAAATTATCGGATGAATTACCCTCTGACACATACGAAGTTTTTC GACTTACTACAG

GAAATCAATTTATTGCAAATGTATTTACAGAACAAAATGCTTCTAATGTTAAAAAAT TTATATCGGCTC

TTCATGGTGGTAATATTCCGAGTTCAGTATCTTATGATAATATTATTAAACTATACT TAGATACTTTATC

AATTAATAAAGTTAGTTTACGTAGTCCATCAGTAATTTATGAATTGATTATCTCCGA ATTATGTAGGTA

TAGTAAAGATATTAATGAACCTTTTAGAAAGATTATTGCTTCAAAAAATAATATTAG TCCCTATATGTA

TACAAATATTAATCTTAAGAAATTACCATCAATCAATTCTACTTTTGCGGCACTTAG TTTTGAAAATCC

AAATCAAGCAATTATTGACAGTATTAATAAGAATATCAATGGTGAAAAAGAGAATGA ATCTCCTATTG

AAAGGACTATTAAATACTAATATTTTAAAACAATAAAATATAATCTTAATAAGATGA TTTATTTTTATG

TTTATTAAGTTTTTTATAAAAAAGATTATAATGAAAGGAATGAATTATAAATATGGC TAATGATGCAA

GTTTGACACAACTACATCCATCAGTTTCATCCGTTATCAATGCAAATCAGTCTAATT TTCTTACATCTA

ATGGTGTAGTTACTCTATTTGCTGCAGACACCTTTGCTAAAGGTAAAGATGGTGCAA TTGATTTTGTTA

GTACTAAAGATGAATTTATTTTTAAATACGGTACTCCAGATTATTCCAAATACGGTC AATCAGCTTATA

ATATTGTAGAGTGGTTAGAAAATGGAGGTCAAGCATTTGTCCTACGTCTTCTTCCTG ATGATGCTACCT

TCTCTCATGCAATTCTGAATGTACAAAGTAAAGTTGTATCTCAAGGTAAAAATGTTT TAACTACTGCAG

GAGAATTGGTTAAATTAGATGATGTTCATCTACGTCCTACTACTGCTTTTATTAAGA AAAATAATCGTG

ATAAGAATATGTTGATGTCTGAATTGACAAAAACTCGTTCTGATGAGAATACTGTTG ATGGTTATACA

AATAACTTTGTATTGCTAGTATATCCAGAAGGTCGTGGAGAAGCTTACAATAATTTA GGTTTCCGTATG

ACTCTTAATGGTTCTTTCGATTCAGCAGTAAATAGTTCTCGTGTTTATAACTTCGAA GTAATTCAATAT

GATTCTGAATCTAATATGACTGTAGTTGAAGGACCATTTTATGTATCTTTCGATCGT ACTGCAATCTCA

GCTTCTGGGGAATCTATGTTTATTGAAGATGTTATTAATCGCTATTCTAAACACGTT AATTGTGAATTT

AATGAAGAAAACTTTAACCGTTTGACTAAATCTATTAATCCTAATGTTAACCCAGGA CATATTGATATT

CTTACTGGTAAATCTAAAGTTCTTCCTTCTGGTAAAGCTGAAACAGTTTATTCCGAA ATTACTCGTGAT

AACGAAGATATTCATATTTCATTACAAAAATATAATGCTCGTGGAGAACTAGTAACT CAGAATGGTAA TGCTGTGCTTAATATTCCAGACCCTACGGATACTGTTGAAGCAGCATTGATTAGTTTAGA TAATGGATT

ACGTGAAAATATTTACAATCTAGACTCTAATAAACTTGCTTACATGAAAGAACAATT CCCTAAACTAA

AAACTGATAGTTCTAGCGAATTTAAATTGGCTATGAATCAAATTATCAATGTTCCAG GAGATGATTCTC

AACCTAAAACAGGTGAAGTGGTTACGCTTATTAATAATAACTTTGATTCATCTAATC CTAGCAGTCTTT

ATAGTAAATACCTTATTGCTAAAGAAGCTTATATTAGTGAAGATAGTGATGAAAATC TTTCTGCAGTAT

TATCATACGTAGATCGTTTGTCTGAAGTATTGAAGTCTCAATTTATTGATTATTCTA CTAAAATGAATG

CTTCTTATACATTAACTCTTCATAATTCACCAAATCCTCAACTTCCGGCACAATATG CGCTTGAACTTA

ACTCTTTGACTGATCTTCTTAATAAGAAAGATCAAATCAATATCTTTACAGTTGAGC ATCAAGGTAAAC

TATTTGATATTCAAGAAACAATCACTAAATATCGTTTAGGTACTGTTAGTGGAAGTT ATTTGGAAGGAT

TGTCATTAATCCTAAACAATGTTGAGAATGAAATTAAATATGTATATGAAAGCTTAC TTCCAGTAGCAT

ACAATGGTTATCAAAATGTACCTGTAGAGATTTCTGATAAATTTGATTCATCAAAAC CAGAAAGCATT

ACAAGTCGTTATAACCGTATCTTAGATCTTCAAAGTGATATGCAATCAGGAATTATT GACAATACAGC

AACTAATCGTGATGAAATCACTTCAGTAGCTAATGATATTACTATTGATCTATTGGA TGTTATTAATGA

AGTTACATTCACTTCTAGCACTACAAATATTGAAAGTGCATGTACAACTTCAGTATC TCATATTCTAGA

TAATATCGTTTCTTTCCATTCTGCAGTTCTTACAATGATTACACCTCAAGGTACTTA TGACTTTGATGCA

ATCATTTCTAATGCTAGAACTCAAATTGAAACTGAAATTTCTAAAGTTTCTACATCT AACTCTAAATTC

TTTAATACAAATCTAATTGACTTTTCTAATCCAATTAAACTTCTTTTGGGTTCTGAT GGTTCATTTACTT

ATGACCCAGATAATTTATCTGAAAGACGTGCTTCTATTAAACAATGGTTAATTAAAG CATATAGTGGA

TCAGTTGATTCTGATCTATTGAATAAAGATAAATATCCAATTGATATCATTTTGGAT GCAAAATATGAT

AGTGATGTAAAAGCCGCTATCGGTAGTTTGGCAGCCAATATTCGCCGAGATTTCCAA TTCTTTGCGGAT

GATGCGGGTGGTTCATTTAGTTCTTCTCCAGTAGATTCTCTATCATGGAGACAGACT TCTGCATTCAAT

ATTAGTTCTCTTAACGTTTCAATATTCTCTCAAGATTTAACTTACTATGATGAATAT ACTGGTAAAGAT

ATTCGCTTCACCGCTCCTTATCAACTAGCAAGTAAGATTCCTTACAACGCAGTACAA TACGGATTGCAA

TATCCTTTAGCTGGACCACGTAGAGGTCTAATTAGTGGTCATAAAGCTATTTCTTGG GTTCCTAATGAA

GCTGAAAAAGAAAAACTATATATTGCTAAAATCAATTATATTGAACAAGATACTAGA CGTACTAAATT

TGGTTCACAATCCACTACAGAAACTGGTTATGGTGCATTATCTAATATTAATAATGT ATTTACTATTCT

TAAAATGGAACGTGATGCTAAAGAACTTGTATCTAGTTACCAATTTGAATTCAATGA TGAAGAAACTA

AAGATTCTCTTTATACTGAATTGAATTCTTACCTATCTAAATATACAAGTGACCGTA GCTGTGAGTCTG

TTGTAGCTACTGTTAGTGCTTCTGACTATGATAAACAACAACGTATCATTAAAGTAA ATATTTCTGTTA

AGTTTAACGGAATTATTGAACGTGTTCAATTAAGCTTCGATGTAGCTAATTAATACT ACAATATTTCTA

ACTAGAGGTAAATAATTTATACTTATTTTATTTATCTCTAGTATTTATTATAAACAA TTATTACTTATAA

GAGAGGATGACAAACATAATGCTAAAACCGGGTTCTAGTGCTAGAGTCTTTGATAAT GACTTAGCTAA

AGGTAAAAGCTTTTTTACCGGATCAATGAATACACAAGAACTTCAGTTTGATCCATT TGTTACAGGATA

TGCATTTATCCTTTGGACTAAAGTTCCTACTTGGGTTGAAAAATCATTCCCAGGATT CCGTAGCCAAAC

TCAAAAGAATTTTAAAGAATTCTCAGGAATTTCAGATATGGAACTACAAACTGCTGA ATATACGCATA

CTTTTAATAACAATGCTTATCGTTTTAATAGTGGTATTACTAAAAACAATACTGAGT TTACTCTAAGAC

ATCAAGAATTCTCAGGTAATCCAATTACAAATATGTATAACTTATGGGTTTCTGGTA TCAGTGATCCAC AAACTGGTATTGCTACTTATCCTAAAGAATATAATATGGAGTATGCTGCTAAGAATCATA CAGGGGAA

CTTCTATATATTGTTACTCGTCCTGACGTAAATAACGTAGAACGTAATAATATTGAA AAAGCATTCTTC

TATACAGCAGTTATGCCTACTCGTATTGCATTAAATCATTTTAACTATACTTTAGGT ACTCATGATGGT

GCTGAAGTTGAAATGCCATTTGCAGGAAACTTGCATATTGGTCCATTAGTTGATGAT TATGCTAAAGA

AATGTTACGTAAAACATACTCCTTTAACGCTCAAGGTATGTTTAACCCTCAAGATGG TTCAATTGCTGG

TGAAAATATTGCTGTATTTAATGATAATGCAGGAGTTACTGGTTCTGGTCTAGGAGA TATCTAATTAAA

TTAAATACCTATCACTATATTAATTTATGGTGATAGGTATTTTATATTTTAATTTTT TAGAGAAATTATA

GATATCTAACAATAATATATAAATGTATTTGGTTGTGAATCTTTATTATTTAAAATA ATTTTTTAAATAT

TAGAATAACAATATAATATAATTTTACTTCTACGTGTCGGTATGCAAGCTGGTTAAA GCAGACGGACT

GTAACTCCGTTTCGAAAGATTCGAAGGTTCAAATCCTTCCCGGCACATCTTTATGGA AAGTTGTCTGAG

TGGTTTAAGGTCTCGGTCTTGAAAACCGATGAACGTTTATAGCGTTCCGTGGGTTCG AATCCCACACTT

TCCTCTTTTATATTATGGACTTTTAAAGTTTAGTGGCTTTAAGAGTCAGCCAATTGT TTGTTTTTCTTTCT

TTATTCCATATTTACTTTAGGGATATATCTTAAGGGGTTTTTGATATATCCCACTCC TTTTGACGTGTAG

CTCAATGGTAGAGCATCTGACTGTTAATCAGACGGTTGCAAGTTCGAGTCTTGCCAC GTCAGCTTATTT

TATTAATACCTTATAATTAATTAATACCTTATAATTAATTAATATAAGGTATTAATA ATCCTAATACGG

TTCTTTAGCTCAGTTGGTTAGAGCAGACGGCTCATAACCGTCCGGTCGATGGTTCGA GTCCATCAAGA

ACCATTTCTCTAAAAAAGATTATATAGAGAACAGTAATATTAAATTCAGTAATCTTA TTCTAAGTTAAT

ATGTATATATTAATAAGATGATAATTAAAGAAATTAATTATTGCTGAATAATATTAA ATTTCTTAATAA

ATAGATCAATTAACTTAAAAAATATCATAACGATCCTTTTTAAAACCACACCTTCAA AAACCATGTAT

ATGATTGATCTATTTAATGAAGTCAAAAGTATTCTTGTATCCTCCTAATATATGAAT ATTTAACCATTTT

_{TTTTTTTTTTTTTGCAAGTTTATATTGGTTCTTGCAAACTCTTTTTTCACGTATT ATCTCTTAAATGAGGT}

AATACGTGTTTTTATTATAAAAATAAATATATATTATAATGATGATTAAAATAATAT ATAGATTGGATT

GATGAGACGATGGCATACAATATTGATAACGTAAGGGAAACTAAGGCAAAGGTATTA AGAACGGCAA

TTAATTCTCTGATTGCTAGATATTATGAATCTAATGATCCAAATACTGCACTAGAGT ATTTGGAGACAG

CTGCTAAAATGGAGGAATTTGTTGAGAATGACAATTATAATTATTTATTAGATTATA ATATGAAGAGT

ACCCATCTAGTTAGACGAGTGACTAGTATTGATACAAATCTCAATAAATCAGAAACA AATGTTGGAAA

ACAAAAGATTAGATGTATGTATGAAAGAGAAAAGTCTGCATATATTTATAATATCAA AAACAAGAAA

GTTGAAAGTGTTTATAGAAATAATAAGAATATTTCTAAGATCAATAAACCAAACTTT AATGAAGATGA

TATTGCATTAATGCGTAAGATTCTTGATTCCGAAGAGGGTAGTGCTATACATAGAAA TCTTATTGGTTC

TTATGTATACAATCATCGAATTGGTAAATGTGGAGTGATTGTCGGAATTACTAAAGC GCATATGTATTA

TACACTTAGTGATAAGCATAATAATACTAAAACTAATGATACCAAGTTTGTTGTGAG ATATCTAGACA

ATACTATGAACAACAAACAAACATCTATTGGTATCTGGCGTGCTACTAAATGTTCAT TTAGTAAAGAA

ATTTCGGACTTTGCAACATATTATACTAGTTCAGAAAGTACGGAAGAGTATGATAAA GAATATGTTAT

TAATTCAATGAATCGTCTATATGAAATTGAGAAGAATTATACTCATAAATTCTTTGA TACAGGACTAA

AGATTTAAAGAATATTAACGCTAATCATCCAATAATAAGGATGATTAGCGTTATTTT TTTTTTTTTTAAT

TTTTTCTAGATACGTTTATTGCCTTCATAACTATCTTATAGGAATCATATGCTATCT TTTCAGGAATTAC

GTTTGAATATTTATTATGGACATCCACTAATTTCTTACGTAGTTCTTCATCGCTAGT ATTAATAATTAGC TTCTGAAACATTCCAAAGATACTCATATGTTCTCGTAATCCACTATTACTAGAATTATAT ATTACCTTAT

TAAATTCGATCTTTTTTACTTTATTAGATCGGCAATATTCATTATCAATATTTTCTA ATAGTTTATTAAG

GTCACTAATAGTCTTTATACCTTTTATTTTACTAATATCTTTATGATATTCAGATAT AGATGCGTATATA

TTATTTTTAGAAAATATACTTATCTCATCTTTATTAAAATGTTTGTTTAAACCATCT TGATTTATAATAT

TAATTCCATTCCGAATATTTTCTTTATTTCGACTAATAATTTCAGTAATAGTACTTT GTCTATCTTTATGT

TTCTCAATAAGATTTTTTACTTTACGTAATATTGATTCATTAATTTGTGATTCTAAT AAATCTTTAATAT

AATTATTATCCATATCTATATATCACCTTTGTCTTTACGATTATATTTATAGAATTC TATCAATTCAAGA

GAAAGATCACCAAAAATAGCTTGCATTGAAATTCCACCATTGATATTTACATTTTCC ATATCCTTAAAG

TTTATTAGTGGGTTAAGGTAATCATAATTATTATTATTATCTGCAATAAATACTCGA ATTCTATTATTTT

TTTTAATAACCTTAATTAATTTACTATCAAAGTTATAATCATAGGTATCTATAGTTT TAATATATAACGT

AGGATCATCTTTAAATATATTACGTTTAGTTCCATAGAATTGATCTATTTCTTTAAA TCCGTTCGAAGC

AATATTTCCTACAGCTACAGAAACGCTATTATATGGTGGTAGATTACTATTTGTACT ATCACTTTTAAT

AAAGAATCCATAACCAGAATTATCATTCTTATTGTAGTCGAGAGCAAATAATATCGC TCCGCCCTTAG

ATGGTGAAGTATGTTTTAGTTTAAATGTGATAATATATTCGTCTGGTAAAGTTAAAT TTGTACTATACA

TATTTTTCCAAATATTATTCTTTGTTTCGTTATCCCTTGAACTTTTAATAATCACTG GATTAGATTTAATT

TTAACATTATTTTGAATTGTTTCTATAATTCTACCATTATTATATGATGGATTATTT GTGATAATTTCAC

TACCGTTTATTTCTTGTATGGTTGGATGAAAATATATTCCTTCAAAAGAATCTTTAG GGAAAATTTTAA

CACCTTTATCATCTATTGTCTTATAATTATATAATAGGTTTATATTATACCATCCAG AGGAAGGAACTG

TGAAACTAGTATATGAATCATTATTTGAATAGCTCTTAATATTAATAGATTTTGTTT TGATATATGCAG

TAGTATCCTTTTTTGCATTAATTATAACATTAACCGTAATTTTTTCAATACTTATTG ATTTACTTTTAATA

ATACCCAACTTAAGGTAACTATTCTTTTTATTAGTATTAAAAATATCTGATCTTGGA TGTAATGTAGTT

ACGCTTTCAGTAGTACTGTCTGTATAAGTAATAATCATTTCATAACCCATACTATCA ATATCATCATTA

TTAAAACTACTTGAGTACTCTAAATTTGTAAAGAATAATCTATTATCTTTAATACGA TTAATATCTCGA

TAGTTATTTACTGAGTCAGCAGTAAAATTTACCGATATAATATTATTCTTTCCTTTT TTTATTGTACTAT

CAAGAACATGCACATACCTACCTTGATCTTCATCATAAGAAACAAATGTTCCATTAT ACGAATTTACA

AACTTATCAAGATTATCATCTCTAAAATCGCTTAATAATTCCATTTCATTAGGATTA AAATCTTTATTA

ATATTTACAATATTTTTTGCAGTATCAAGGTTATTTATCATTAATCGTACATTTCCA CTAAAGTTGTTGG

TCAATCCATATTTTTTACTTTTATCTAAGTATATTTTACCTGTAAATGATTTAGTAT AACCTTTTTTAAA

ATAGTATGATGGTATACTAGTTAGACCTTTATCATCTAACGTAAAAGGATCTACATA TCGACCATCATT

ATCTGTAACTTTACCCATTTCAACATCTATTGATGCTAGATTATAGTTTGCATTTAA TATTTCATCTTTA

TTATCTGAAAAATCAGGAACTGTATGCCATGGAATTGTTTCATTGATATCAGTACCT AATAAATCTTTT

GATTTTTCATTTAATGGATGTAACATATGTTTTTTTACATATCTTGGACTTTGTACG GTTGATTTCATAT

_{TTTTTTCCTGATTAATAATTTTATTGATTGTATTTAGAATAGTATCAGGGAATAC TTTAATTGTTTTCTT}

ATTAAATTTTTCAACAGTATCCATATCATTAACAAACATTAATAAGTACCATAAGTC AGTTGTTTCATA

TAATTCCTCAGATACATATTCCGGTCTATAAAATTGGTTTTCCGATATATCATAATC AATTAAGTTTGA

TTTAAAAATATTTTCATACTTTTTTAACAATGGAAAACCTAATACTATCTTTCCTTC TAATAAATAAAA

GTTAGATATATTACTAAGCAATATTTTATTAACGTTTATTGAATTTATTCCACCAAC TAAGTCAACAAA TCTTGAACTATCTAAACTATTTCTAGAATTATCTACTACTACCAAAATATATTCACCACT TTTCAAATTT

CATTATATAATTATATGTTACTATATTCTTTTTTATCAAAAAAAAAAAAAAATGCCA TAGTATATTATG

TAATATACTATGGCATAATAAATGTTACATCATTGGATCATTATTATCTTCAGAACT ATTTTTAATATTA

GATATATTTAACTTATCTTTAGTTAAATCTTGATTTGTTTCGTTAAATAATGTATCA AACTTAGTCCAAT

CAAGAGTAGACATATATATTTCTGAAGCTAATTTTTTCCTAAACAATCTTTTCTTAT TATCGGTATCCTC

ATTTTGTTCTGACTCTGTGAAATAATTACCTACAATAAAATCTATTGTCTGTGAAAT ATTATTAATTTGT

TCATTAACATTAGCAATATTCATAAATACTGGTGTAGGGAAATTAATAGTGATTTCT TCAATTTTTACT

TCATCTTGGTTTTCGTTATAATCTTTTTCATCATTTGTTTTGTTCTTATCTTTACGA TCTCGTTCACCATA

CTCATAACGATATAGCTCTTGAATTATCTTAGTAAAGAATTTACTAAACGTTTCTTG ATATCCAATAAC

TCTTCGAACAAAATTACTATTCTGCATTGATAGATTTCTTGCAAAATCAACTTCATT AGTAGCATCAAT

ATAATTAATTGGAACACCTGTTCCATTAACTGCCGATTTCTGTAAGAATTCTAAGAA ATCATCATTAAT

ATCAGCTTGTATACCTGGAATAACATCAATATCGAAAGGCTTATCTCCATTAACTGT TGGAATAAATGC

TTCTTCTGTAGCACCTAAAGTTTTAAGCATAGTAGATACACTATTTCCGGGACCAAT ACTATCCATTGA

AAATTCAGTAGTCTTTAAATCTCGGATAAGTTCTTCAATAGTTCCCTCAATATCAGA ATCCATATCAGA

CTCTACGTAATATACTCTTCTATCTCTACCTTGATTAATTTTTACCATTAAATTTGT AATTAATGTAGAA

AGATACATTTTAGCAAAAAATAGACTATTATTTAATCTAGATACACCATACTCGCTA GTGCTATCTAAA

GGTAGATGATACACCTGATTTGGTTCTAAGAATGTTATAGATATATCTTTATTGATA ATATAGTCTTCT

CTGACCAATCTATATATTACATCTTTAAAATCTTGGTTATCTTCTAAAAAGTCTTTA GATATTTTATCAC

TAATTCCTTTTACAAATATATCAGTAATTATCTTGTATTTTTCATTACTAGTCACTC CTGAACCACTCTG

ATTTGATCTAGAGTTATAATACATTGTAATATCTCCATTAACACTAGAAGATCCTTG TGGGGCATTACC

GTTAAGAGTTCCTGCAATAGTACCTAATATTGAACTACCTTTAAATGAATTATTGCT ACCATTCTTTTC

AATATACACGTATCCTAAACATACTCCATCAATAGATATTTTAATGATATCTTCCGG ACTAAATATTTT

TAAGTAAGATCCGGTAATATTTAGATTTTGAATGTCTTTAGATTTTTTACTTGCTTT TCGAGATTCAGAT

ACAAGATTTAGAGGGTCTTTATAATATTTTACATTTTTAGATATAGACTCATATACC TCATTAGCAGTA

CTTTCTACTAAAATCTTTTCAATATCTTTAGGATTACTTTTAGAAAATCTTTTTCCA TTTTTAATATTAG

ATGATTTAAATTCAATATTTTCATCATTCATAACACTTTCAATAAGATTTTCAATAT TTCTATGATCCAC

GTTAAAAGATTCATTTAGATCATCTTCTTCAGAATCAATAAAGAGATTATTGGTATC TAATTCATTAAA

TTCATCTTCAGAAAGAATACTTTTAAATTGGCTTTCTAGATCGGTAACCATGATAAA CAGATCACCCTC

AATTAATGTATTCCGAATAGAATTTCGAATAACTGTATTTAGATTATATTTATCAAT CAACTTAGACAT

ATTACCATTGAATTCTTTTTTATCCGTCTCCCCTAAGGTAGTATTTTCATTATTATA ATAGTATGATATT

GATTGTTTTGTTACATCGTCTGGAGACATAATAGAATCTACATACGTATCAATAGCT GTACCCAATTCC

GGAAAATACTGAGATATTAGTCTAAAATCATCATATCTTTGCCATCTTAGTTTTTCT TCAGCAAACTCT

CCTGATGAGAAACTACTTTCAACTTTTTCCTTAAAATAATTGTTGTATATATCAGAA CTTTTTTTATTTT

TCGTATTTTTCATTCCAGTATTCTTAACTTTATCTCTCTGTATGTCGGAGATAATAT CAATTATACTTCTT

CCTGAACTGTTATTATTACCGTTTCTTCGTTTAATCTTATTTAACATATCATGAAGA TTACTTAATTTAT

CTTTTGGTATATCTTTCTGGTTCATAATACCGTATAGATTTTTATTAACGTTTGCAT TATCTGCCATTAA

ACTTATCCACCTTTCTAAATTGATGAAAAAAAAAAATATCATAGGAAAAAATTTCCC TATGATATTCA CTAATATTTATTTCATATCTACGAATATATATGATTGTTCCATAATATAAGTATCATTAC AAACTTCAAT

TACAAGCATTTTTAATGATGAATCCTTGTTATGATTAAAGCATAATATATTTATAGA TGGATGTTTACT

ATATACTACTGGAATATAATCACTAAATTTTTCTTCTTTATATTTTTCATATGCTTC ATTAATATCTTTTG

GATAGTTCAATGATCCGAGATTATCCTTAATATTTGTAAAATAAGGTATTTCAGTAA ATTGGTCTATAT

CGACAATTAATGGTTCAGGATTCTTTTTACGAATATACTTAAAGCCTTTGATAAATT TAGTTGATACGG

TAACACTAATATAATCATCTAATTCAGGTTTAATCATATCATCATGGATAATAATAT TATTATTATCAT

TTTTATCAATAACTATTGAGAATGTATATTTATTGTCAAATTCAAGTAATTTTATTA CATCATCATCACT

AAGCGTTATCTTTGGAATATTTAATGAATTTTCACTAAAAGAATCTAATACAGGAAC AATATGATCATT

ATACGCATTAATATCTTTTTCTTCTAAATACCATTTAATAAAAAAGTCTGATTGTCT AATAAACTTTATA

TAGTTATCGTTATAGTCTATTTCTATAGAGACAATTTTATCTGATTTATTTTTACGC ATTTCAAAAAATT

CTATCATATGAATAGAAAATGTATTCTTTTGCATAAAATCATTTACTGTTTTCATTA TACCTTTTTTATC

TAGTTTTCTTTCAATAAAAGTAGCATTGATATACTTTGGTAGTTGTTTTAGTAGTGC GTCATCGTTTAGT

GAGGGAAATGCAAAACCATTATTAAAAATCAACCTATCCCCAACATTAAGTACATTC CTAAATTGATC

TACCATTTCTTCAATAGAAACTACAATTTTTTGAGCTTCATTAGGATCATCTACAAT AACTTTATTATTT

TCTTCAATATACAACTATAATTCACCTACTTCTTGCATACTTTCAGAATCTATTGAT TCTCGAATCATAC

CCAAAGCATCTTTAATATTTGGTAGATTATAATATTTAATGCAAAATTGTAAAGGGT TATTACTATTAT

AATCATCAATAAATGATTCTGTAATATTCTTATTACCTTGTTTAAAAGTAATATTTC CGATAAGACTTTC

AGGACTAATATTTAACGCCATAATAATATGAGGGTATAGTGCAGTTAAGTCAATATC GGTTACATTAT

CGAAAATCATATTTGATTTTTTACCCATAATATCAATACCGATTGGATGAACTTTTG ATGAGTCTGCTA

CAAACGCACCTTTAATTTTTCCATCAATCTTAGGATATAATGAACTATGATTATTAC TAATTACAAACC

CACCATTATTATAAAAGATTTCTGTAAGGTTTCTTAAGCATATTGTTTTCTTAAGTG CTTTTGTTATTCG

AGTATGTGTTAACGAACTAATTTGATAAATTAGATCTAAGAATTTAGTTGCTTTTTC GATCATCATTAA

GAGAACTGTATCCTGAATGTTATATAGAATGAATTTATAGTAGTTTTTAATATATAC GTTAGTGATGTC

TCCGTCACCCTCTTCAAACTCATCCTTTTGCATCCCTACTTCTTTTTCACCTATGTC GTTCAATTTGTAAG

AGTCTAAGACTCCCATAGATAGCGATAGGTAAGTATTTGATATTATCTCCAACTTTT CCCCCGCTTCAC

ACCGTACGTGAGACTTTCACCTCATACGGCGTTCCATCACTCAGTTTATATTGTCAC CGATATATTAAT

GACAATAACTAGTCGTTAACTAAGTTTCTTAATTTAGTTAGTTGTGTTTTATTTACC CCGGTAGGAAAA

TCAGTACTATAGTGAATTAGATTATGTGAATAAACAGACAGTAATACAAGATTATCA AAACTATTTGA

CCCACCTTTTGATCTCGGCTTTTTATGATGTATAACTAAGTTATCTATTCCTATTTT ATATAATGGTATA

TTAGTGATAGGATCCTTCTTCTGTTTTTTAACCAGACCGGGAAGATACATTTTATAC CTTATATTGGGA

AAATTAGAACTATTTGTAAGCATATTAATAAATTTTAATATTAACTCATCGTTGTTC TTAGTTTTCATAA

TAGGCGTCCAATACTGTTTATTTATGAGATAATCTTTAGTATTTTTACTGGATTGTT TCCGCCACATCCA

TGTATTAAATATAATGTCTTTATACTTATAAATTTCAGTATCAGGTTTCTTATACAT TTGACTTTGTCGA

CTCCAACTATATAAAATTCCGTTAACTAAGTTAATATAAGCTTGCATATTAGTAACT AAATTAAAATTA

TATATAGTTCCCAATATAATAGACATTACCTTTTGATAATGACCTTTTCTCAGTTCA GACCTTAATAATT

TTTTCTGATTATACCAAAACTTACTAAGATTTTTAAATGAGATCATCACATGTCCAC TTGCAAATCGCA

TATACTTAAAACCTACAAAGTTAATTACAAAGTCCTGACCTTCTTTGATAATGATTT CACTAGTTTTATT CCAGTTTAAAGAAACTTGATGTTTTGTACACCAAGAATCTAAAACAGGTTTAAATCTTTC TACATCCCA

AGGATTCGGACTAATTATTATAAAATCATCAGCATAACGAATCATTCTTATCTGCAT TCGATTACCAAC

GGTTTTCAAATATTGATCTTTACCTTTTCGCCTATAATATGACATATTATAAAACTT ATTATAAGGATGT

GTTTTGTGAAATTCAGATCCATTAGAAATAGCCTCATTATACATGTTTAAGTCATTG ACTAAGATTTCT

AGATCATGTAATAAAACGTTAGCTAGTATAGGACCAAGTATAGAACCTTGAGCTAAA CCAATCCCTTG

ATACTTTGTGTCTTTAGTATCTATAGACATAAGAAACTTTATAGATCTTAGTAGTTG CGTATCTCTAATT

TTGTGATTATACCTTAATTTATCAAGTACTATATCTAAATTAATAGTATCAAAATAC TTAGATAAATCA

CAATCTAGTACTGATCCATTCTTTATTTCTTTAGTGTTATTTACTAAAGCTGACATG GCATGTTGAGTTG

AGAGATTACGTCTAAAACCATAAGAATCAGGATAAAATTGATATTCCAAAATAGGTT CTAAAATATTA

AGAATACATTGTTGTGCTATTCGATCTAATATATTAGTTATTCCAAGAGTTCTAAAC GAACCATCCTCT

TTTGGAATGTCAACAAGTCTTGAATATGGTTTTATATCACCTTTTATTCGTTTCAAT AATAGGCTTTTAA

TATCTTTGTAATCTTGTTTTAGTAAATCATCTAAAGTTTGACCATCTGGTCCCGGAG TATTTCTTCCATC

ATTAGACATTATCCGTTTAATAGCATATTGAATATTACTATCTTTAATAATATATCT AGATAAATGCGT

AAAAGATGGTTTACCATTTAAAACATCATTATACAATTTTATTTGGATTTTATTGAA ATCAAAATATAT

AGAATGTAAACTTTTTGTGTCTATATTAACACACCTTCTTACAAAATCAAGCTCTGA ATATAAATCAGG

CAATTATATATCATTGTTTTGAGTGACTTTGGGCTTTCCCATTAATGATACATTACA TATCATATTATCG

GTTTCTACCCAAACTTTCAGTCTGTATTCATTTAACTTCACCGTGACTAGCAGCTAA ACCGTTAAATTA

ATAATATAAAATTATCTACAGACCTTCCCACGTTCCCTACATCATAGAATATAGTAT ACTTAGGTTCTT

CCTCTAGGCTCTGTGTGATTATAGAAATAATCTGGTTCCCATTATATACCATCCATC TACGCAACAAAC

AATACGTATTTGGAACACAAGTTTACTAGCATTTCTACTAGCACATACCTGTACATT CAGAAGTTCGTC

AGTCTTAAAAGACATACTAACCATATATACCTCCACCCGACCCATTTGAGAGGATTG TTTACCCTTTCG

TCAACTTAATGTTACGCTCTAAGTTAGCCGTCTTCACCCAGCTTCACACATAAATAT CACTACTTATGC

ATGTGGGAGTATTAGTGTACATCTGATATAACTTTAGGGAGTTATATAGTGTATTTG ATGTAGAGTTAT

TCAATATTATTATAATACTGAACTTTAGACACGCCTATGTGTATCATAGACTTTCTC TAAAAACATGTC

GCACGCTTATTGATATTGGCATATAACGCCATTTGATCTAAATATGTTGTATATCCA GCTACTTCATAT

ATGGAAGACTTATCTGCAGGATTATTGTGTTTTTCATCCATTTTATGATATACATAT TTATATTTAAAAT

CATCAGGACACATTAATTCTTCAGGAATCGCATTATTCTTTAGAATTCGATTATATA TTGTGATAAAGT

CAAAATCAGCATTCCACGCACTAGCAAAGTCAGGTCGATGAACTTCATTGATATAAT GAAAGAAATCA

CTAATTAAATCAATTTCTTTATCATATTCATAAATATTAAACGTTAAGTCTAAATTA TATTCTTTATATT

TGTTTTTTAGTTCATCCAATAATTTAGTTTTATCCAACATTGCGTCTTTATAACCAT CATGATCATATTT

TAATGCAAAAGTTTCAACAGTAAGATTCCATTCATTTACAAGTGTAATAATATTAAT CGGAGCTTCTGC

TTTCTTTTGATCTGGAAATCCAATAATATTTTGAGTATCTACTTCGATATCGTAAAA AGATTTCTTTAGT

CCAAAAAGATTATTATCAGGAGCATGTTTTTCTAAATAACGATGAATATAATTATCT TCAATATTCTTA

TCAGAACCATGAATTCGATAATCTAAATGCATTTTTTTAAGATTTCTTCTATCACGA AAATCTTCAGAC

TTCATAATATTATCATAGAATATTTTTACGCTAGGATCTTTTAACTCTGTAGCAATA CTTTTAAATATAT

CTCTGTTATAACATCTTACTTGCCTTACTTTTTCTTTATCAATATAGTTTCTTACAA CATTATCTTGAAAT

TCCGGTTTAGTAATATAATAATCCATCATTGGTTTTTCAATAATATGATGTTTTTTT GTACCGTCCTCTT CTTTAGTGACCATAATAAGTTTATCAAAATTATCTACTGCACCAGAATTTCTTGCATCTT TCTGGTTTAA

ATATGTTGTCTTAATTAGTTGACCCAAAATATACACCACCATCTAAATTTATATAAT TCCTTGTTATTTT

TATTTTATAAAATTATATTCTAGTAAGATTAATGATATCAATAACTTTGTTATATCC ATCGAATTTAAAT

AAATCTTTTCTACTTATAATAATATCTTTATCTAGATTTTTAGCATATTTAAGAAAG AATCTCATATCCA

TATCATGATAAGTACTAATCATTTCCCATTTTTTAGAATAATTTTTAGGATTATTCT TCATATGCCTATC

AATAAATTTAGTGGATAATTTTTTTCTTTTAAACATGTTTAAATTAAAATTATTACT TTTTCTACCGTTT

ATTATTGATAACAGTTTTTCTTCACTAATATTATTATTTTCCGCCATTACTTCTTTT TTGTCTAACGGTAC

_{ATTTTTGAAATCTAATTTATCTTTATTATAAGCCAATAATTTACTATTTTTACTA ATAAGATCAATATAT}

TCATCATCCATGAAAACTGATGCGTTTGTTATAAAGTTTACAGTATCGTTAAATACA TATATTTTTTCTT

TATTAGATGTATCACTACTACTATTATATTTACATATAGTATTTATTAGATACTTAA TAGATTTAATACT

ATTAAGAGTATCATATTCCGCAATACGGAACATATATTTAAATACATAGGAAATATA ACCAATACTAA

GATAATCAATATTTAACATTAACGTATCTATGAAACTGCATAAGACTTTATTAATAT TCATATTATTTTT

CATATGACTTGACTTGATCATTAGATTAAGATGAATAATAGGTTCCACATCTTCGCT TTTATATGATTT

ATAATATTCAAAAATTTGCGGTATAATATAATCGCATAAAAATTCTTCATCTATATT CGAATTAGATAA

AATAAAATTTATATTATCGTATGAATATTCCATATAGTCACGAAATAATATTCTAAT TATAGAACTATT

AAATTCCATAACTGACCGCACTGAAAGATAAGAATTTTTACTATTTACTATCTTATC AATATTCTTTAT

AAATATATGATTAGGTATTTTCATTTCATAATAATCTATATTATCAAAATTTTTTAT AATAAAGTCAATC

ATCTTATCAGATATTCGGTGTCCGTAAAATGATACTAAATCTTTGATAAATTCTTCG CTGTATTCATAC

ATATATTTATCTAATTCTTCGTTCGGTATACTTATATAATTATCTGTAAATCTTAAT AGTTTATCACCCA

AATTCCCATTACTAGGATCAATTTCTATTGTAAGTTTCTTCAATATACTTACCAACC TTTCTATAATTAT

ACTAGCTTTAGATCAATTACGCTTTTTTCAAATTCATTTAAATGTTTAGACCAATTG AATGATACTTCTT

TATACCTATTAATTTCATCAATAGTCATTAAGTTTATTGTATTAAAATCCAGCGATA TCAATGAAAATA

CTTTATTCTTTAATGAACCGATAACATTTGTATTTATAAGTATATTATAAATTTCAT AATATTTTTTAGA

TATATCTTTATTCATTTGTAATGAATTTTCACTAATAAAATTTCCACTATCTGATAT CACATAATCAATA

AATACTGTATCATTTATTATATTAAATATACTAACCGGATCAGATATGTCACGCATT ATATTAGTCAAT

ATAGATTCAATATGTGAATTATCATTATTACCTTTATTATACTGATATAATAAAGGT AATATTTCTAAA

ACAAATATAGTTCTCTTAGACTTCCATAATGGAGGCTTATTTAAGTATAATGATACT TGGAATTTATCA

TCGATATCATAATAATTCTTTTTTAGTAAATCTATAAATGATATAATGAATTCATCA TTATCAATAATCT

TTAGTGATTTAATTATATTATCATATAAGTTTAATTTTTTAATTATCTTCATGCTTA ATTCAATATTTTTA

ATTCTAAGTATGTTCATTATAATATTGTCTGAATTTGATTTAAATATACATAGACTT AGAATTTTTATAT

AATGGAATATATACATATAATATCACGCTTCCTAATCATTCTTGCTTTTCATTATCG ATTACTAAACTAT

GATTTTCTAAAGAACTTAGCCATGGATCATAGATATTATTGAATCTTTCTTTATCGC TAATATCTTTAGT

AAATATATTTAAGAATGATTTTTGATATTTCTTATCATTATCAAACCATGAAGATAT AAACTCTTTTCC

ACTTTCTTTACTTAATTCAGTTAATGTAGTATATACTTGGATTGCAAAGAAAGAACT TAATCCTACTGC

ATCAACATCTAAATCATTATGTGAATCGTTATCAATAATAATATAGCGATTATCATC AACAGGAGTAT

ACTTATTCAGTGCAATCTTTTGAAACTCAATTTTAATATTACCATTAAAACTATATT CACCATCAATAT

AATTGTTAATAATATAAAAACTATTTGTAATAAGTTCCTCAATACATTTATCAGCTT CAGCAATAATTA ATTCATTACTATATTTTTGTAAATCTTCATAGTTTTGAATTCCTAAGGATTTAAGTCTTA CAGCAATAAA

TCCTTCAGTAATTCCAGATAAAGAGATTAAAAATTTTGCAGGATTCAATGAATATAC TAATTTATTAGT

ATTATTCTCAGTAATAATTTCAATACTATATGGAATTTCCATATATCGTTCAGAATT TTCAGTATATGTG

TTACTGTCTTCATCAGTAACCACCCATTTTTTTCTAGTTCTTCTATTAATTCTAGAA ATTTTATTTTTCAT

TTCACCTACATTATTGCTGTTATTTAAGCTGATATTTACTAAGATAGTTTTTTCATT ATCGTGAGAATTA

ATAATTCTAAAGTCATAATTATTTTTTCGAAGATCACTTGTAACTTTCGGTAATTCA TTATTTTTAACAT

CTAATTTTACGCTAAACATTTTTATCATCCATTCTATTTTTATTTTAACAATAATTC GACTACTAATATT

AATATTAGTAGTCGATATAATTTATTTTTCTGCATTAAAAATAATAGTTTTATTTTC CATAAATACAGTA

TCTTCAATATCAATGCTTGGATTCTTCGTTAAAATTAAATCCACGTCAGAAGTATGG AATTCATCATTA

TGGCTAATCACAAATATTTGTTCCATATTTAAATAATCTGTTTGTAGATCCAATACT TCCATAAACTTA

CGTCTATTATTTGTATCTAATGTAGCATCAACTTCGTCTAAATATATAATGTTATAC CCTGAAGATACG

GTTTCAATCATTGACAATGATAATGATAAACTAGTGATTGCAGTTTCACCTTGAGAA CTTAACTTAATA

TCTGAAAGATCAGTTCCGTTATCTTTAAAGACCCTTATAAAGAAATCTTTTTCAGTG ATATCAAAACGT

ATACTAAATGATTCACCGTAAGCAACTTTTAATAAGTTATTTGTATCAGACGCAATC TTTTTAAGATAA

TTATCAATAAATATTAATGGAATACCTTTCTTAGGATCTAATGATTCTTTAATAGTT TTAAAGTCATCAT

ATACTTTTTCAATACTAGATAGTTTATCGGTAATATTTGTTGCAATATTAAGTCTTT TTTCATTATCTTCT

AATTTATTCTTAACTTCAGATAATGCGTTATTATTAATATTGATAGACGTTTCAGTA TTATTTAATAGAT

CATTATTATTTTCTAATGTTTTTAGTCTGGATGTAATATCATTATAAACTGAATCGT ATACTTCTTTTTT

ATTAAGAATACTTTCATAGTTTGATCTCAGATCTTTAAGAATATTCAGTATATCCAA TCGTTTAGATAC

TGTTTTAATATTCTTATCATATTGATCTATTGATTCATTATTATCTTTAATACTTGA AGATAATTTTTCTT

CTTCCAAAGTACTAGATTTCAATAGTTCTTCATACTCATTATATGATTCACGCATGA TATTGTAATTTTC

AATAGACCCTTTAATATTATCAATAAGATTGGATACTTTGTCTCGGTTGTTGATATT ATTAATTAGATC

AATATATAAATTAGGTAGTTTTACAAGACTATTTTCAATATGATCACGGTTTGGTAA AAATAAGTCATC

CTCATTTAAATTAATAATGCTTGCAATATTACGAATATTATTAAATTTAGGTAGAAC TTCTTGACGATA

TTTATCAAAATATTTAATAATATTTGACAAATTACTGATATTATTATTAGTTTCTAT TCGATCTTTTTCT

AAATTACTTAAGGTATTTTCTAATTCATCCAACTTAGGATATTCATTCTCTTTATAT TCTAAAGCAATTT

GAATAAAAGGACAACTATCAATATTACATGCTTCAGGTCTTCTATCTAGTGTTGTTA GTAAATTAGATC

TACTATTAATATCACTAATATTTTTATTGACTTCCAGAATTTGAGATTCGATATCAT TCATTTTGGAATC

ATTAGATTTAAACATACTTAGATAATATTCGTAGTTGTCAAAAGTAATATTATCGTC TTCAAAGTAAGT

ACTTTCATCCATACTCATAAGATTTCTTAGAGAGTCCAGAAGATTACCAGTTTGATG AATACTATTATA

CATATTATTGTCATTCATAATAGATTCAACATTTTCCATACTAGTTTCATTCAATAA AGAATTTATATTC

TTATTAACTTCAGTCAGATATTCTTCATTTTTTTCTAATTCGTCATAATACTTTTCA GGATTAAATTCTTT

AAACGAAGATATTTTATTACGGTAAAGACTAATATTTTCCCTAATTTTCTTTAATCG GTCTTCAGAATC

AGTATTTTTTTCCTTTAATGAATTTCTCGATGTTTCTTCTTTGATTAATTTTTCTGT AAATTGTTGATGTT

TATTATAAATATCATCACTTGTATATTTTTCTAATGCTGGAAATTGAGAATATATAT TCTGTAATCCTTG

GTAAGATTCATCAAGACTCGTATTAATTGTATTAATAGTATTATTAAATTGGTCAAT CGATTTATTAAT

ATCTATTTCATCAATAGGTAGATTTAGTTCATTTAATTTTTCTTTAATAAAAGAACT ATCCATATCAATA TTATATTTAGTAATTGTTCTTTGTTCGTTTAAACGTTCTTTTTCAGATTCTAATGATTTA ATATTATTGGT

TAATTCTTCTTTATTTTCTTTTATAGTATTAATATCATCATACTTAGAAAGATCAGA ATTTAATGTCTTA

AGATTTTTATCTAAAAAAGATAATTTATCTTTAATAACATTAAATCTTTCTAAATAA TCATCCATAGAA

GGTATAAACTTATATAAATAATCCTTACGTTCGGCAGTTTTATAATCAATAAAGTTA TTCATATTATTA

CCTAATCTAGCAACTGTCATATAATCTTTAGTAATTCCAAGCTCAGTACTTACAATT TCTTCAAAACCA

CGAATTCCACCATTTTCATTTAATTCCGTACCATTCTTAGAAATAAATGACTTATTA TGAGAAGAATTA

TCACCATAATAATGTTTAATAATATACTTATCATTATAATTAATATAATGAATTTCT TTATATCCTTTAG

TATCTGGAATAATAATGTTATTTCTAGAGTCATTTGTACCACGGTAAGGATTCAATG CGGAAAGAATA

ACTGTTTTACCAGAACCATTAGAACCAATTAACATAATTATTTTATTTTTAGAATGG GAGAAATCAATT

TCAATTGACTCTTTTCCCATTCCAGCATATATTCCGATAAAGTTTACTAATTTTAAA TATGTTATTTTCA

AGATATCACATCTTTCTAATTATTTAATCTTTTCTAGACAAACTAAAACTAAATTTA ATCTTATTACTAG

CGGCATTATAAATAAAGTTTGTAATTACATCGTTAGGAGATTCATTATTCTTTTTAC ATGACTTAACAA

AATCTTCATAAATATCATATCTACAATTTAGTAATAGCGTTTCAGGAATGAAATCAA TGATTTCCATAT

TCTGAATATTCATTTCTTCAGTAATACCATTATTATCAATATAATTTAGTATAAATA ATTCAATAAGATT

ATAATCAGAGTTATTTAAGATTCCTGAATAAATTAGATCTTTTTCACGATTAGTATA ATTATCAATATA

CTTCTTAGGAATAATAACCCTAATATTTTTTCTAGGTTTATCAAAAATAACTAAATT GATCTTTGTATTA

TCATGACCAAAAAGATTATTAGATTTTTCATAATCTACAACTTCTGTAAATTGCTGA TATGACTTACAA

TGATAACAGTTAATTGTTTTGATATGATCAACCGCTTTATTGATCGATACTTTTCTT TGAATCATTACTT

TATTACCACAATTGTTACATATTAGAGTACATGGTTTTGTATTATATAATGAATTTG CGTTATTTTTTGT

CATGAGAAATCACCCATTCATCCATAACACTAATATAATCTTTATTCTTAATATCTA GAAATTCATTAT

ATAATTTATCAAAATCTGGATAAAATTCTTCTTTTTTACTTTTAACACGATTAATAA CATCATTATAATT

TGGTGAAAATAATAGATCTCGAATATCCCTAAGACTATGATACGGCAAATTTTCTTT CTTTACGCTATT

ATACATTACTTGTGCCATGTTCATACTTCTTTCATGATTATAATCAATTTTTCGAAT AATTCCAAATTTT

CTAGTCTTCAAATCAAAGCAAACCATATTTCGAATATGATTATTGTACTTAGTACTA TATAACATATCT

TCTTTAACTTGTTCTGAAATAAAATCATTAGTTGTTAGTTTAATAGGTGCTTCTAAA TCTTTTCTATCCA

CTACAATTTTATTTTTTTCAGATTGATAATAATTATATACGCCATAAGAATCATTTT TACCATAATTCGA

GATAGTTCTAATATTAAAAACCGCTCTTAATAATAAATTATCAGTACTGCTAAATTC ATATGATAACTG

TAAATTGAAATCTCTTGCATTTTTTTCCACATCTGAAGCAAACTTTAAAAATTTTAG AGCTTCACCACT

AATATATGATGTAGTAGTTTTATCTCTAGCTTCATTATATCTATTTAAGTTTGCATT AATTGTGGATCTA

ATTATCTTTGATAATGTACCATTTACATCATTTACATTAAAATTTTTCATGAAAATC TCTCCATTCTATT

TTTTATAAATATTCATAATTGAGAATAATTCTTTTATTTCTTAAATCACTAATACGA TCAATATTGATTC

CTAATCGGTTACAGTGTTCTAAGCTTGAAAGAATTCTAATATCTTTATTGATTGATT CGATATCTTTTAT

TGTAGTATTTTCTTTTCTGGAAGCATATAATAAAATTGATTCAGGGTCATTTGAAAA GATATTTTGATT

GATCCATCTATTATATCGATTATTAATAATATTGGACGTTGTATTCACAGTAGTAAT AGATTCTTTGGA

ATCAATATTTCTTACAATACCTACTCTTTTTTGCGGAGAATTATAAGTAAAAACAAT ATCGTTACTAAT

ACTTTCTGGAGAAACTATTCTGCTATTATTAACAGTAAATTTACTATTAGTTCTACG TGTTAATAATTTA

TAACTATTCCGTTTATTTACGTTAGAATCTAAATCATCACTAATCTGAAATGATACA TATGAAATTAAT CCACCAATATTATTAAACGCAGGAATTAATAAGAGATCACTATATTCAGATGAAATCTTT CTTACGTTA

TTATCAATACGTCTTTTAATTGTTTCTAATGCTGAAATCGTTTCCCCTTTAGCGTAT AATTTATAATACT

GCTTAATAAGAATGTTAATAAATTTGATTGTTTCTTTAATTTCAGTTGTAGGAATTA ATAAATTATGAT

AATTATTATTCCTATAAGTTTTTCTTTCTTTAATACTAGTTGACATTAAAAATCATC CTTTCAAAATTAT

TATTATAATGACTATGTAATATTGACATAAATTAATTCTCATGTCATTACATAGTCA TTATAATAATAT

ATAAATATAGTTAAAGTTGAAAGGTAATTTTTTATTCTTCTATTTCTACATAACTGA ATTCTGAATTATC

AGAGAATATTACGCCTACTTCATTATCGTCTTCATCATAAAGAGATTCAATTATTCG GTTATTAGCTAA

ATATGAATCAATTACTTCATTATTCATTTCATTAGAAGAGTATACTGTTTGATCTTC ATCTAAGAATATT

GGTTCTGAAGTATTAATATCTACGCACATTACATATCCAATACTTTCTAAATAGTCC GCAAAGTTCTCG

GAATCATCTTCAACAATTACCACAGATTCAGTCTTTTTCCCTTTTTCGTTAACCGAT TTTTTAGCATCAT

TATTCTTAATAGCATTTAGTCTTTCTTCAATGAGTTTATCATAATCTTGTTCTTCAA CTTCATTTTCATTA

TCTTCGTTATTATCATTTTCTAAGTTTTCATCTACAACTTTTTGAAGGTCTTTTCGG TTTGTATTTAATAA

TTCATTTACAATTCCTTTAATAATTAAACTTTGATCCCCATTAATATCGCTGTCTTT ATTATTAATATTG

TATTCTTTAATCTTAATATCTGCCATTTTAACTTTAAGATCCGACATTGCTTTAATT AATTGCATCTTCA

TTGTCTTAAGACTAATCAGGTTAGATGTCTGGTCCGTAACAAACCTTGGGTCTGTCT TCATTCTAGAAT

TTTGTGCCTTACTTCCCCTATCAAAATAACCTTCAGAATAAGTATATAATTCATCAA TAGATGATAATT

_{CTTTTTTAAGCATATTATATTCATCAATAAGTTCTGGATCTATTGAAAATTTAGG TTTATTTTGTTCTTC}

CATATATTTAATTTCACCTACCTATTTTGTAAGAGTATATAGTGATAATACTGCTTC ATTACCAACTTTA

CGTATCGATTCACCTTGTTGGGATAATATATTTGTTTTTGCATTAATCAATTGATCT GCTTCTTTATTTG

CTTCAGCACTGAATACCCCACGAATTGAAAGCGTATCCCCATCATAATCAGCACCTA GAGCAGCAGTT

AATGAGTTATTAATAACTAATGAATCAGTAAAATAATTTTCTGCTACTGGATAGTCT GGAAAAATGAT

TGGATAGTTTTCCAGATATCTATCTTCAATTTTTCGATATTCAGTATCATTAGTGCT TAGCACAACAATC

TTTGAAGGGAAGATGCTTTGATAATTATCTACTGGATATCGAGTACAATACACATGT TTATCAGAAGT

AATATCAATAGCTGCAATATACAATAAATCTGTTATTGTAAAGTTTCTATCAAGATC AGTATGAAATAC

TTCTACTGGATATTCATTACCTTTGTCGTCTTTAACCGTAATTGCTTTAAATCTAGC AGGTATATTCTTA

ATAAAGTTACTTACTAACTTATTAATATCTTTATCGGTAAATTGATTTTTTACATTA TCAATAAAGACAT

CTTCACCTTTTTTATTCTTTACATTTGAAAATTCTTCAATATGGATATCAATAAAGT CATTAATATATTT

TACAAAGAATGGAAAGAATAATGCACATACCTGACTTAATGGAATGCCTACGGTCCC AAATTTTATTT

CTGTATCGTCCCATCTATTTGTGTTTGATCTAGGAGCAGAGATTACTGATCTAGTTG CATAATCAATGG

ATTTTCCTAATAGACCCCTATGCACTAAGCCGTTCTTACCAGAAATATAGTCGATAA ATGTTTTATATA

CGTCATATATAATTGTCTGCATTTGAGATTCGGTATTTGTTCGGACAAAGCTAAACG ATGATTCACCAT

CTAGACTAGAACCAAAACGAATTAGTTTAGCGTATAGATCATTAATCTCATCTACGT CTGCTATTCTTC

CGGCTTTTGATGTGTTTGGATTGAAGTCTCTTAAGAATGGGGGAATAACGATAAATT TATTTATAAATA

ATGTATCTTTATCAAATTTTTCAATAATATTTAGTTTACTATCACGTTGTAAACTTT CTGTTTTTTTGAAT

GATAATTTTTCAAAATTATTGTATAAGAAACTTACACCGGTTTCTCCGTTTACATCA TCCTCAACTAGTT

GACCATCTTTAATGGTAAAATATTTTAAACCACTAATACATTCTTCAATTCTTTTAT CTAAAGATATGA

TTAATTTATATACTACTGGGTGAAATATTCTGGTATTTAAATCAATATATGCAAACT GATTTGATCTCG ATTTAGACCCGATTTCTCCAAATATTTCATAACTAAACAATCCATCTTCAGTAGGATAAT TCGATTGAT

TAAAAAATATTGGGTTTGTTATTTTTGGTAAGTTATTTTGTTTTACTACATTATCGA TATCTAACAAATT

TATTTTCAAAGATAAACAACCACCTTTCTTTTTTAGGTATCACATTTTAAGATATAA TAAATATTTGTTT

AATAATAGTATAAGTATTTAATTAAATGCAAGGATCTTAGAAAAAAAAAAATAAGAG AATAATATGT

CATTATATTATTCTCTTATATACTGATTTGTCTAGTGAATCAATATTCTTTAATGAT ATTATTATTTATA

AGATAACTTACAATAATATCGATATCAATGGCAAAATTTTCTTTATCATAAATATCT TTATTTAAAGAT

GTATATTCAATACATTTACTGATGATATCATCTTTACTGTATAATGATTTATCCTTA TTCATTACAATCC

AGATGATATCTACATTATTTGAAGTATTTTCAAAATTTCCATTATTATTCAAATCAA TTAACATTTTAAG

AATAATAACAATGTATTTAATAAATTCATTTACAATGTGACCATTAGTAATAATATC ATTATTATAATA

ATGTTGTTCGTATATTTCATAACTTTCATTAGATTCAATTTCATTAATAACAATCTT TCTAGGGTTTAGT

ACTTCTAGTGAAAATACATCCAATAAAAATTCTAGTCTTTTATTTAATACATGCCGA TTAATTCTTGAA

TTCTGTTGTTGATGATTCTGAAGATCAATATTATAATATTGTTTTATCAAGTTATAA ATAATATCTACAG

AGGTAGTATGAATTTTATTTCTTGAAAATTTTTCATTTTTTCGATATTTATATAGGT AACTTAAAACTTT

TGCATAACTGTCATCAACACCAGTCTTATTTTTACATACAATATCTTTTAATTCAGA TGAGCTAATTGTT

AACGATAACATATAATATACCCCTTTTCTTTATAGTTTTATTTTAATCAATACAAAA CACTTAGACATA

TCTAAATGGATATCATGAATATTATACTCAGATAAGGATTTTACAATATGATCTACA ATAATGTGCATT

TCATTATCACTTAAGTATTTTTTATTATTTTTTCTAGATAATAGATTAATCTTTAAT GTAAATAAATTTTT

ATAGAAATATTTTGAAGATTTAAATAATTCTGTATTAATTGATTCTTCTAAATATTG CACATAACTATT

ATTTAATAATTTTTTAGTATTAACTGTCATATATATTTGATCTTTATTAAAATTAAT TTTATTTTTAAAAT

CTTTAAGTTTCATAATCATAGAATAATAAATCCATCCATTCGTATTTTTATTTAATG AATAAAATACTC

AACTAACATAAGAGTTAGTTGAGTATATATCCTAGTTATTTAGTAAATATGCAGCTT GTAAAGTATCTT

TATCAAGACCATAATCCCTATTAAAGTCTCCATTATTAACACTAATTATTAAATTAG AAGGTTTTATCT

TTTCAAATTCTTTAACTTGTTCTTTTGAAAATAATGCAATAATATTTAATACGTCAC CATCATAGTCTCC

ACCTAATCCGGCAAGAACATTATTACATAGGCTTAGTGTTTTATCCGAAATATCCTT TTTAACTTTGGC

AATATTCATTAATAAGATACTTGAAGTGGATATTGAAGGATTTCGATTTAGTATAAT ATATAAACCACC

TTCAGTTTTATTAATCAATTCTTCCATATAACGATACATTTTTTTATTAAATGTATT TTTAGTATCTATAT

GGAATTTTTCAGCTTCCACTAAAGAAATATTCTCTGAAGTTGAAATAAGATTAATTA ATGGACCCTTAT

ATAATTCGTGAAAAGTAATATAATTCATATATACTTCATCCATTTTACATAATGGGT CTGGAGATATAA

CGTTTCTTGCAGAGTAGTTAATTCGAGTACCTAAAATCTGTTTACGAATTGTTCCTC TTTTACCTTTAAT

ATTATTTTTAATAATACTATCTACAATTTTTAACACGTCAATCTGTACTCGATACTG TAATTTTAACTTC

TGAATTTTAATATCTTCATAGATTTCTTCATCACTATTGACAATATCTTTTAACATA TTTGTATGATTGA

TTAAGAAATTGTAGTCATTATTTATTTCAGAAAGCCGAAATAGATTTTCTGAAGCAA TTAACTGAGCCG

GTCTCAATTTAGGACTAAATATTGGTAAGCAGTCAATAAACAATAATCCTTCAAAAT ACCAACGGATA

ATACGTTTATATTCTAATGAATTTTTCTGTTTTGGATCAACATACTTTTGGAGTAAT TCAATAAATCTTT

CTTTAAATTCATCCAAACCGATATTCCGATCCTCAAATTCTTCATGCTCACTACCTT CTTCATCTTCTAA

ATCAACAATATTTCCATTTGCATCAATACGCTTATTATACATAATCATATCAATAAA TTTAGTACCATC

AAATAATTTGATTAATCGATCAAACATAATAGGATTAACTACATAGTTATTCTTAAA ATCTACATAACC GAAGTTATCAATATTATCCCTTTCAACTTCAGGACCATAGATTTCTTCAGAAAATATTCC ATCAATAGA

ATATTTCTTTTCTTTTTTTGTTACTGGTTCATGGTTAGTAATAATTTTATCTTGTTC AATTAATTCCCTAA

AATCGATAATCCGTACTCTAGTCAAAAGTAATCAAGCATCCTTTCTAACACCTTTTA GGCTTTTATCAT

ATTCACGATTAATCATTACATCCACATATGAATAATTCTTAGCTTCCGCTTCAGATA TCTCTTCTTCTGA

GAATCCTGAGTTGTAGATTGTTCTTTCTTCAACAATATTATCAATAATATCCTTTTT CTTTTTATTAAAT

TTTGTAATAATCTTCTGATAGAAGGAGGTTTTACTGATAAATGCAGAGATCACTGTA AAAACAATTATT

GTAATCATAATACATTCAAAAATAATAGTAAACATTTCCATCACCATTCTTTATTTA TTTTTTTATTAAT

CATCATAATCAGTTAAGAAACCTTCAATATCAGGTTTCTTTTCAAAGAAGAATGTTC CTGAATTATTTG

GATCATATTTCTTACAGAAAGGTACTACGGTAAAAGAACTTCCAGGGTCTCCTGAAC TAGTACTTACT

AAATCGATCTTTCCAACAAAGCTTGGATAAATACCCCTAGCGCTTACTGATAATCCA TTAGCTGTTGCA

GATTGTGGACCCTTTACAGAACCTTTTAGATAACGAGTAAATAGATCCATAGAATTA ACATTATTTGA

GAATCTTACTAATTCGCTGTTAGGAATATTATTTACTAAGTAATCTTCTTTAATATT GCTAAATAGTGTT

TTTAATTTACTTACATTATTATTTTTTGGTCCAACTAAGCGATATCCGCCTTTGGAT AATTTTTGAGTTA

GATCATAAAATAGATATTCATTAACCCTTAAACGTTTATTGGATAAAGAGTGATTAT CTACTTTTAAAA

TATTGTAATAGTTTGTAATCATATTTCTAACAATCGCATAAATATCTTCTTTATCTT CTGAACGTAATCT

TAAATTGGATCGAGTTGTATTATCTAGTAAACGTTCAAAGGAGGATAAGATAGATAT AGCTTTATCAA

AAGTCATTGAATTATTATTTGTAAATACCGAACCTAGTTTTCTCTTCCAATAATCAG AATCAAAAGATT

TTTCATAATCAATTCGATTATATTTAAATAGATCTACTAAGGTTGCAATTAATGTTG CATTAGATTTTTG

ATCGCTTTCAATCCATTCTCGATTAACTTTTAATGCAATACTTTTTGTCAACTGGAA GAAGTAATATTCT

GGACTAGTAATATCATGATCTTCAGTTTTAACGATTTCTACATAATTATGAATATTA AAGTATCTTAGA

GTTTCAACTACACCTTTTCCTGCAAAATAGTAGTTCATTACATTTACAGTTTTCTTA AATAATAGTGTCA

TTAACGCTCTAGTTTTTAATGGTTCACCATTATTAAAACGTTCATCAATATCAGATA GTACAACCTTTTT

ACCCTTAATCTTGATTGGCATAAACATTGTTTTCAATACAATAATTCCATCATTAGT ACGATAATACTC

GGAGTCATTCATTTGGAATACTGGGAAAAATTCATTTCCGTTAATTAAGAAGTATTG TTGATCTAATAA

TTCAGGGAATAATAGTTTAATTTCTTTTTGGATTGTTTCTTTTCCATCAGAAAGTTC CATTGTAACTTTA

ATTCTAATAAATCTAGATTCCTCGATATTAACGGTTGGATGGTTAATCTTTCTAGCT TTACCTTTTTTAT

TTTCTTTCTTTTCTTCAGTAACTTGTTTTCTTTCCTTATAGATTTTCCGATCTGTAT CAATTTCACATTTA

ACAAAACGAATACCTTCTACAAATTCAAGTCCTTTAAAAACATCTTCAACTAATTTT GGTAAGTTTTCT

TTAGATCTAAAGAAGATCACTTCCTCATTAAATGGAGCTTTTTCTTCCATTTTATTT TGAAGATCATTAA

AGAGTTTTCTTGACAAGTTTGGCACAAACAAACAACTCCAATCAAAATTTATTTTAT AAATTTTTATAT

CGTATAAAAACAATTAACTATTATTAGATAAAAATTTGTTTTTATATAAAAATAAAA ATTTAAGGATGT

GTATATACTATGTTGAGAAACGGTGAAGAATTTTTTAATGAATGGTCTGAAAGATCA GGAATACCTAA

ATATGAATTAAAACGTCAATGGAATATTATGGTAGAAATGGTTATGGATAGCATCAT GGAAGAAGATT

TTACCAAAACAGTATTACCAAGCATAGGCGCTTTTGAAACTATTGTTAAACCTCCAT ATATTGCTAGAG

ATCCTAGAAATGAAAAAGTTGTTATTGCACAAGTTAGGAAGCGAATTAATTTTAGAA TATATCGCAGA

TTTAAAAAAATAGTAACAGGATTGTTATAATTTTCGTAATACAGATATTTATTTCTG TATTACGAAAAT

_{CTTTTTAATTGTTATTTCTTTTAATAATCTGTTTTTCAATATAAATTCTATCTTC TTGAGATAGTCCATTA} TATATTTCTTCTAAAGATTCAATATCTTCATTATCATTAATTAATACATCAATATACCTA TCTAAGATTT

CTTTAGGTACATTAGTTTTTAAATTATTGATATTATATGATAAATTGATCTTAGAAT TAGTAAATTTATT

ATCAACAATCTTTACACTTAACTGATTTCCATCATTACTAATATTGATGCTTGAATT AGTACTTTCACTT

GTAATATTAAGTTCAATACTTTTTAATATTTTGTTAATTATATTTAAATCCAAGTTA AAACATCCTTTCT

ATTCTTATATATTGTACATTTATATAATATATAAGAATAATATTAGTTGATGAATCG AGATTTAGCTTC

TTCGATAGTCATAATTTCTTTTTGCATTTCCTTAGCTTTAACAATTTTTGAAGAAGT GGATTCTTTATCT

TTACAAACTACAATATCAGTTTTTGAAGATACGCTACCTGTAACTTTATGACCGAGT AATTCTAATTTC

TGTTTAAATTCATTATCCCGAATTCCTGTAAAAACAATAACTTTAGATTCTTCAGAA GCATTATTAGAT

AATTCTTGTTTAATAGATTTTAGTTTAAATTCATTAATCAAGAATATCAATTCTTCT TCATTATTCGAGA

TACCGTTTAGTAATTTTTCTGCCTTAATATCTGAAAATCCTTCAATATTAATAATAT CTTCTTTCTTAGG

TAAAGATCCATTTACAAAGAATTCGTTAATTACTTCTTCCAAGATATATTCCTTACA GAATAGTTTAGA

GTTTTCAATACCTAATCCTTCAATACCTAATGAACCAAGAATTTGATAATCATATAG ATCACGTTTGTT

ATTAATTGCATTCTTGATATTATCTAGTGATTTTCTACCTAACCCTTCAATAAAGTT ATCATCAATACTA

TCATAATCTATACTATATAAGTCTGTGATTGAAGTCCATAATTTATTTTCATATAAT TTACTAATAGTAG

ATTTGTCAATACCTTTAATGGCTAGTTTATCAAGATAGTTAGATATCTTTCCAATAA CGTTTCCAGAAC

ATTCTGGATTATTACAGTATGCAAAGGTTTGATTATCATTAATAACTACACTTTCTT GCTGACATACGG

GACAATATTTGGTAAATTTGTCAGGAATAATATCTTTGTTATGATCACTATCTACTT TATCAATATATGT

TAGTGTATCATTCCTATATTGTACTAAAATTTCTGAACCAATACCTAAACCTAATTC TTCCGCTCTTGCA

AAATTATGGAGACTTTGTTTTGTATGCGTACTTCCATTTGAAAATGTAACTGGTTCA AAATGTACTAAT

TTAGTAATTCGTGAAAAATCACCTAATTGATAGCTAAAATCAGTAATAACACTTTTT TTCTGTTCATAG

GGTAGTTTAACTGCAATCGAATAATGTGGAGTACCTTTAGGAGTCATTCCTAGTTTT TCACGATAATCG

TCATCTAAAATTTCAACGACAATACCATCAATCATAAATCCATAGTTATATCGATTA TTAATAACTTCA

TTATAGAAATCATTAAATTCTTCAATGACTTTTTCTACTGAATTACTTTCACTAGTA ATACTGAATTCTG

AACCGATTAAACTATTTGATCCTAAGATATTAAAACTATTATCTCGTTTAGATAATG TAATTTCGAATG

GATAATTATCTTCATCGAGGAATTTAATATCTAGAGGGACAAGAGTTAAGAATTTAG AGAATTTATGA

GCATCGTCCCTACCTAATATTCCAGAGGTTGCGGATCGTGGATTAACATAATTATTC TTTGTATAATCA

TTTAACTTTTCTAAATTATCATACGTAATAATAACTTCATTTCTAATTGCGAAAGGT AGTTTGATATCAT

ATTCTTGTAAAGGATCTTTAGCGATGCTCTTAAATACATTAGTGAGATCTAACCCGA TACCGTCTTTTC

CACGAGTATACGCCTTATCAAACTTTCCATCTTTAAAAGTAGTAACTACTGAATTCC CATCAAACTTTA

ATGTAAATAGGAATGTCGGGAACTTAGAAAAAGGTTTAAGCTTATTAATCATTCCTT GAATTACTTTTG

GAAAATCATTAATATCTTTACATTTAAATAATGTTCCTGTCAGATTTTTATATTCAT GCTTCATATTAAG

AATACCTTTATCCGTTTTCGGTAATGATCCTACAATTTCTTCACCAGTTAATTGTAA GTATTGTTGATAT

AATTGGTCATATTCAAGATCAGACATAATTACTGTATCTGTATTATAATACATGCTT GATGCATTTTCT

AAATATTCTTTTACTAAATTATATTTATCATGTTCTTTACTGTCTAAAATTCTTTTT GATTCTGTATAATC

CACATTTTTCAATATCCACACTTCTTTCTATATTATTATTTAATATTAATCTTTTTT CCATTAATGGTAAT

ATAGTTATATTCACTGTTATAAGATACATTTATAATGTCCATATCAGCATCATATAC TTCATCTATTTCT

TTTTCATTAACATATATTTTTCCATTGTCTAATTTTATTTCATATAATCCATCACTT ATAACTATAACATT ATCTATCTTTTTATTATAAGTTTTAGATTTCTTACCATCAATATATATTTCACCATCTTT TAATAACACA

TTTAAACCATTATTATATATATTGGCATTTCTATTTTGAGGAAGAGTTTTATGTTGA TGAAAAATATTAT

TATATACTTTTTTAATTTTATTTATCACATCATCACAACCTTATTTAATCTTAAGAT ATATCCTATCACA

CTATAAAAATGTGATAGGATACTTTTTATTTATTTTTATACTTATTAATATCAAACG AGTCTTTATTATT

GGTATATTCATTAAGCATGGATTCAATATCTTCATCACTTAATTTTTCGATATTATC AAAATCATTTTTA

TAATCTGGATCAGTATTAATTTCAACACCTATAGATTTAAAATATGAATTGATAATT TTATTATTATTA

CTAATAGTGTCTGATTTCTTAGGTAATTTAATGTCAAAAGGATTTCCGAGAAGTTGA GCTTTTACTAAA

TTACTTCTATCTTCAGTATTATTTGAATAAGCATCAGTTAATCTTTCAATAGGTTCT AAAGATCCTACTA

ATCCTGAATTGGTATATTCCATTTCCAATTACCTTCACATAGATTCGCAATTTCTAT GCAGTTCTCTTAT

GAACTTCTCTAAGTTTCCTTAGAAGTTGAGACTATATCTTTATCTTATTTAAAATTT CTTTTTGTTTTAA

GATACTTCCCATTTCGCCTGTCATTTGCTTACAGACTACATCAATAGTCGTTGAACT TTCTTCCAATAAT

TGTTGGAAGCTTAGCTGCTGATTATCCATTATAATTGATACTTAGGAATATTATATT TATACCAGAATA

TAATATCTTTTTATCTCACCATATATCATTCCAATTATTTTTTCTATCTTTCGATAA CATTCACGCTTATC

ATTACTGATTGCGTTTTAGTTAATTGGACTTTAGGAGTTTCCAGCAATTAAAGAAAT TTTCATCATATA

TCACTATATAATGCGGCAAAATTTACCGACTCTAATTGGAGTATTATTAGTAACATT ATCAGAATTTTT

CATATCTTTAGTTTTTGTTGGAAGATTCTGGAAGTTAGTATTACCTTCACTACGAAT AGATGTTTTTTCA

ATAGGCTCATGTTTAAGTCTAAGCATATATAGTTGACCCATTTCAATAGGCTTACTA ATTCCACTTAGT

TTATAACGATCGATATTGAATTTATCACGAATATCTTTAAGTTTAAAAATATCCATA TCATTCCAGAAT

GGTGTAAATTGAATATAAATTCCATTCTTTATAGTATCTTCTAGATAATGATCCTTA TCGCTATCACTTA

ATTGATCATATATACTGATTAATGATTTATACATATTTTCATCAATAGACTTAATAT ATTCAGATAATA

AATTAAACTTTTCTTCACGACTATCCATATGTTCCATTCGATATCGAATAACTTGAG ACATCATATTGA

ATGTATGTTCAAATGATTGTGAAGGATTTAATCGGTTATTAACGCCAAAAGGATTAA GAATAATATCC

GCTCTATTTTCTAGGCAAGAATCTTTATCAAACTCCTCACCATCAATAGTTTCAATT ACAGGCATTTCTT

CGTCCGGAAGAATTAATCCAATAATTCCTTTATTACCATATCGACCAGTTAGTTTTG AACCTTTCACAA

GAGGAATTCTTTCTAAGATTGTAAATACCGCTACAATACGGTCAAACACTCTTCCCT CAGACTGAAATT

TATTTGCAGGATCATTAAATGCTGCAATCTTATTATAAAATGCAGATAAATCACTAC TGATATTATTTC

TTTTACTAGATACAATAGGTTTTAAATATTCTACAACTTCAGAGTAATATTTTGAGA TAGAAATATATT

CATTGTACATCTGATGATTATATTTTTGAGATCGTAACTTATCAAGACTTTCGTTAT TATAAATATCAAT

GTCAATAACAATACCTTCAGCATGTTTTACTGTGTCAGTAGCAAAGATCTTTCTTAA ATTGACATCTTT

CATACTGAATCCCATATCATTATAATTAATTCGACGAATTCCCATTAACTTACCATC TTTAATTTCTTCA

CCAATACTAGGAAAAGTTCTATATGATTCATCATCGCCATATAGATTTAATAGTACA TCATTGGTATTT

AGATTGATCTTAACTTTCTTTATTAAATAGGAAGCCATCTTTTGAGCAGTACTCTCA GAAACAACAATA

GAGTCTTCATTTGTGAATCCTTTGTATGGAATATATACCGCATTGAGATTTTTACCA TACTGAAAGTTC

ATATCTTCGTCATAATTTTGATCTCGATAAATTACTTTGTTTTCAAATTCTTCATTT TCATTGATATTATC

AATTACTTCATTATTGAATTTTAGTCCAAAGTGTTCTGTTAAATGTTTTGCTTCTTT TCGTTCTACAATA

TGATAGAGTTCTTCTTCTTCATTAAATAATATTGCCGTGTAATTAAATTTATTCTTG TAAAATTTTTTAA

GAAGTTTCCATCTACCATCAAGCTTTTTATATCCAGTAGAATATTTACCTACTTGAT TTTCAAAACCAG TAAAAACTAATGGTGGATCAGCTTGTTCCAATTGAATATTTTGACTTAAATGAGAAGTAA ACATTTGTG

ACCTATTAGAGTTAGTCTTATCTAAGTTTGGAATGAGTAATGTTTCGGCTAAGAAAT CAAATTTACCTT

TATATTTTTCATCATTAATCTCTGTTAAATCCAAAGTATAACCACACTTTCTTTTTT TTTTTAATATACTA

ATCTATCCATTATATAAGAGTTATTATATTATACGCTTATTGGATAGATTAGTACTT GTAATTATTAAG

ATTTATTTATCATTTTCTTTTTCGATTTCAATTAAATTCATGTCAGAGTCATAGTAT CTTCCATCTGAAC

CAACCCAAATATCTTCATCTTTATTAACGCAGTCAATAAGAGTAACAATATTATCAT TCTTGGTAGATT

TTGGAATTGTTTTAAACACTTGATTTTCACCATAAGCGTCAAAAGCATTTCTAAATT CTTCATTAGTATT

ATATAGTGTAACAAAATCTTTACGTTTAAATTTAACGTCTGGAAGAGTAGGAATAGA GTATCCTCCTTG

CGGTGAACCATCTAATAGTTTATTATCTTTAAGATAAGCAAACAGTGAAATACCGTT AGAGAATCCAT

TAAGTTGATCAAAAACAGAATTAAATGAGTATCCTGAAGCCGAAATACGGGACTTAA CAATTAGTCCA

TCAACTTCTAAACCTTTATATCCAGTTTCCTCTTCCTTAACATTTTTACCCGGATTC AATTTAACAAATG

TATTAGATAAATATCCAAAGGCAGAACCACCTGGAATAGCTTCATCAATCTTTAGAT GATTCAGCGAA

GCTTTAGTCTTAACTACTGGATTAATTTCAATCTTAGTAGTAATATGATTAATCGCA AATAACATGATA

TTTGCTTTTTCTAATGCACTTGAGCCAATTAATCGTTTAATCATCTGATTATTGTAT TTTGCTTGTGCTGT

TGCAGACATCTGTCCACTCATCTTTTCTTCTTCACTGATGTCTTTAGTATACATAGC AGCAATAGAATCT

AAGATAATAATTGTCGGATCGAACTCATAAATTGGTTTACCTGTAATTGGATCTAAT TTACCTGTATCA

TGTTTAAGTTTATCGCCCCTGCTAAGTTTCTCTTTTTCAATAATTTTTACTAAACCA TAAAGAGTTTCTG

CCGATATTCCTGAATTAAGAAGATTATACTTTTCAAGAATCTTTTCATCAGCCCACC CAGTAATATTTT

TAATACGAGCTAATGATCCGGCATGCTCATAATCTAGATGATAAATTTCAGAATTTT CATAACGATCA

ACAATATTACATGCAATTTGTTGAATTAATGTTGATTTACCAGACCCGGATTTACCT ACAATGGTAAAT

AATTTACCGGCATCTAATCCCATCATTAATTCTCCCTTACTATCATAACTTGCTAAC TTTGCATCAATCT

GACTGAAACCCGTTCTATAAGTTTCAGTAAAATTTTTGGATTCACCTAATCCATCTT TCAATAACTCTTT

TTTAACTTCATCTGTAATTAATCCCATACATTTACTTCCTCCTTAGATATCATACAT TATAAATCATTGT

TATTACAATAAAATAATTTTTTATTTATAATAACATCATACTACAACATTCCCTTCA GTATTTTTATTTT

AACATATTTTTGACGTAAAGTGGAGATAATTTTTTACATCATAATTTATTATAAAAT GCTATAATGAAG

ATTATACTTCTTCATTATAGCATCATTAATTCTAATACTTAGATAATATTAATTTAA CAACATCGTCAGT

ATTTATCATTTCAAATTTTGACATATTATCAATATAATCACGTAGTTTATCAGTATC AATCAAATTACA

ATAATCATTTCTTTTTACAATGTCTGTAACTATTTGTCTAAATCTAGTGTCTGATAT GATTACATTTACA

TCTTTTATAAATGTATCAATGAAAATTTTTATTGTATTTTTTGCAATATTAGCTTTA TCAACATCAAATA

TTTTATCGATAATTTTATCAATCTTGAATGCATAAAAAAGTAACATTTCATAGTTCA TATCAGGTAATT

TATTTTTTGCATACATAATAAATACTTCGATAGGGTCTCGCTCAATTTCTTCAGTTT TTAATAATAATTC

ATAAATATAGTCTCGGATAGATATTCGAGATAAAGCTTCTTGCATTTGATTAATAAA GACTGAAGTGTT

ATCTAATGATATTTTTTCTAATATTGTGATTAGTTCACTTGCCTGTTCATCAACTAA TCTTTTATAAATA

GTATTATCACGCATATTATCTTCCTGAATTATCTTAAATTCATTTACAAAAGTCAAA AATATTCCTCCTT

TCTTCAATAGTAAATAATCACAAATATATAATATATATTTATTATTGAATTTTAAGA TCGTTTATATTTG

AGATGTTTTCTTCTTTAACATCAGCAAAATCTAAATTAAATGTATCGGAATCATCTA GTAAATCATTAT

CAATTCCTGCACCAGTAAGAAATTGGGATACGGTATTTAACGTACGCTTATCATTAA TGCTTCCCGGTA AATCTTGTAATGAAGTATATCCATACATTGCAATATTTTTATACATTGTAGATTTTGCGT CTTGTGAGTC

CGCTCTAGGGCTTAAGAATTCTTTTAATGCATATTTAGCGTCAATAGCACTTAATGC AATAGTTTCTAA

GTCACTGATCCGTGCAATCTTATCTTCGTTTGTTACTTGGTTGGTTCTTAAACTACG TTTACTAATATCT

AATGAGTAGGTATTCTTTTTCGATAAGGTTTGTTATACTGATAGGTAAAGATATACT ATAAACGTATTC

TTTTTCCCCCAGTCCAAACCGTACGTGAGACTTTCATCTCATACGGCTTTCCATCAA ATTTATTTCATTA

CTTAGAATAAATACTTAATAAATAACTATTCTAATTAATGAAAATTAGATTTGACTA AGAACTTTCTCT

CCACTATTTATTATCATAGCTTCATCGATACTTCATTCTCTCTTACTCCCTATAAAT AGGGTATCAAACG

TTCCCTTTAAATTAGGTATATAAATGTACTTAGGATCCACCTGTTATTTATAACAAT ACTTACATATAA

GTATAATATGACAACCTATTAGTCATATTAGCTAATAAAGACTACAATTTTATTTCG CCTATTATAAAT

CATTAAAGTGATTCGTATTCCTATCCATATACATCTACCCTAACCGCTATAAGTATT ATTAGCGACTTC

ATCCAGCTTCACACATATTAATTACTCAATATGCATGTGGAATATCATTAATAGCAA TTCATGACTATT

ATTTAGGTTAGTCACAGCTTATTCATTTAAAGAGTTAATTATATACGCATATATAAT CATGCAATCCTC

AATATTTTTACATATCTTTCTGCATAACGTTTCGCACGTAGTCTCCTTACGGGAAGA TAACCTAATGGT

ACTGGATATCTAGTTCTTAATGGATTATCTTTATTTCCATCATGACGATAATAGATA TATTCTTCTAATG

GTACATTCATAAAGTCTAGTGTTTCTTTAATATCTATCAGTTTTGGTTCATTTTTAT TCGGTAATACTTC

TAAATAGAAATTATCATCACCATTAGTAAATTTTTTCATATACGATAAAAATTGTTC GTCACTCATTTT

ATCGTAAATATCTTTATACTTTTTAGCATTAGAACCAGTTTTATCTAATTTATTGAA TACGTCAATAATA

TACTTTTGAATTTTATTTCTTTTTTGTTTATTATTAGATACTTCTTCATTTAATTCT ACCGATTCATTGAG

ATTATCTTTTGTATCCATATAATATACTGATAATATTTTAAATAAATTAATCGAATT ATCTTCAGAAAT

ATCATACTTCTTAATGTTTTTATCTTTAAAAGGAAACTTGTCAATACTGAATTCAAT AATCTTTAGACC

ATCTAGATCACGGTTATCGTACTTATCAGTATATAACTTAGAAAGATAATTTGAACT AATTTCCCTAAT

TTGAGAAGTATTTGATAATCTAATAGATTCAGGATAACCAAACTCAGGATAATAATT AAATAATACAT

AACTATCATTTTCTTTGTAATAAGGAAGACTAATATAATCTATTAATTCTTTATTTT TTTCATTATATAG

ACCCATTATCATAAGTTTTGTAAAAGGTTGAATGTTTCTTAGTATTAAGTAAATAAT AGTATTAATAAC

ATTACTATTCAACTTGTGATAATCAGTAAGAGTATCACTATACTTGATGATATTGAA TAGACTCATTTT

TATACTACTATTATAACTTCGATTATTATCATTAAGTATAGATTCAATATACTTAAT GATATCTTCTTTA

TTATTAATATCATTTCTAAATATAATATCCATTATATAATCATTAAAATCAATTTTT GTAATATCAATAA

CCGAATCCTCATCAATAGATATTACTCTTTTATATAATGATGATAATGGGTATCTTA CAATACCAGAAC

GGGTATATTTAGTAATTGATAATAATGAGGGATGAGATATTAACTGATCTAATTTTA TAGATGGATAT

AATTTACTTTCTGAATCCCTGAGTTTAAATAATTCAATACCATAAGTTCTCATAATG GTCATAAATACG

CTTACTAATTGAATTTCTCTTATAGTTGTTTTATTTCCTTCTGCACTTCTAATTATT AGATCATTATCCAA

GTATTGATTATAATCTTTAATCTTATCAGAGAAAGTATTAAACTGATCTATAATATT AATATTATTTTTA

TCATAATATATAGGAAACTCAATTACCTCTGTAAACATATCAATATTCTTTAACTTC TTTTCAAAATTG

GATGTAAACTCAGATACTTCCATTTTTTCATCGTTATAATCAATTCCAAATATTCTA GAATTATCATGA

CTATCTATTAACGCAATTTTACTTAGTCTATCTTTAGCAGAACCTATTACCCTATCA ATAATTAATGTAA

CTTCTAATTTACATTTATCCTCTGAAGGACTATTATCAAAAGGTATATATTCATTAT TATCTAGCATTAA

TGCATTATCTGTAAATTTTCTTTCATTCCCTAGGTACTCATTATATTTTTTATTCAT ATAATTATCCAACT ATAATTCACTTCCTTTATATTATTCACTGGTATATCTATATGTTTATATTACTAGTTATT AAAATCTTTTA

TCAAAAAAAAAAAAAATATTAATTATTAAATACATAGTATATAACAATTTATTTGTT ATATACTATGTA

TCTTTTTTTCCTTACATTATATTGATTAGAAATTTAAACCTAACCAGTATCTAGCAA ACATAGATTTATA

TGAAACTAAATCTACAATAAATATTGATACGAAAATAACCAATGATAAAGCAATTAC CCAAGATAAG

AATACAATTACTTTCTTAGATAAATTAAGATTAAGTAATCTTTCTTCAAATCTTTTT AGTGTAAAATTTT

TCATGTTATCTTCTAAGAATAATAAGATTGTAATGCATTTTAATAGTTCATTAAAGA TTCCCACAATTT

TGTTACTACCATTATTTTTATTTACTATTACTGTTTGTTTTTCCACTTTCTCCACAC TCCTAATATTATTA

TTTTCATTTTATAAATTAAAAAGTTAACCTATCATCAGGATAATAAAAATATCCAAT GATAGGTTAACT

CGTTTTTCTCTATATTTAAATAATATTTAAACTATTAAAAATTATAATCAATCTCAG ACTTTTGAAATTC

AGCTTTCATTCGTTTTAGTTCTTCTTTATCAATATTTTTTTCTGACCTAATAGTAGT ACCTGTTGGCACTT

TTATATTAGTAATCATTTTGCCTTGAACTGTTAGGATAATATTTAAAGTAATCAATA TAAGAGCCAAGA

GCAATAATGAACCAATAATAAAAGATGAAATATATCTATCTACTTTCTTTACATCTT CTTTATGTTTAC

TCTGGTTGGATTTATATTTCGTACTAAGATTATCCATTCTTATTTTCACTTCCATTC ATTTTATATTAGTA

ATATAATTTATCTATATTACATAATGATAATATATAAACAAAATATGGGTTATTACG CTTTTATAAAAA

TTTATAGTTAATGTATAATAATATTATATATTTTGGATCATAGAAAAATATATATGC TTTATAAGTATA

TATTATAAATTTGTAGTAAAATAATTAATTATGGAGGATTAATATGAAAGAATCTTT AAAGTTTAATGT

CAAGGAAGTAAGAATTCTTAGCAAAATCGCATCTAATGAATATGCTAATGAGGAAAG TCGGTATGAA

AGCTTTTTATCTAAATTGGAAACATTTAATAACTTTCGTTCAGGATTTTTATATCTG TATCTAAAGAATC

TTTCAGAAAGTGGATTAACTAAACAAGAATCTTTAAATAAGGCTATTGATAAATATG TCAAATAATTC

AATAAGATTTAGAATAATGGCAGATATTTATTGTAATAATAAATTTATCAATGTTGA AGAATTAGAGT

TCACTGGAACGAACGAAAGTAACGCAAGGAAACAATTAACTGGTTACCTTAATAGAC TAACAAGAGA

AAATAATAATGGTAGATATACAGCTAAGAATATTAATATAATACCCATTAAATCCCA ATTTCAAAACA

ATATTGAAAATCAAGAACAACTAAATCTTTTTAGTAATGATATTAATGATGATTTAT AATCTAAGTAAA

TCATCATTAATTATCTTTAATAAATTATGAAAGTAGTGATATTTTTTTGGCTAAATT AAAGAAAAGCAA

AAGACGAGTATCCTTTGAAACAATTGTTAAAAGGGTTATTGAAAAACATTTTCTTGA AAAGTATGATA

AAGCAGAACTAGATTTAGATAACGAGGAAACGTATCAAATCGGGTTAGGTTCTATTG ATATTGATAAA

TACAATATCAATCCTGATGATTTCGAAACCTCTGGAATTTATTATTACAGTAAAGGG AAAATATCTTTA

GATAAAGATTCATCTCCTTTACGAACAATGAATGTTAATGTAGGAACTGTTAAGCCT TTATATGACGTA

ATATATGAAATTGAAATTATTTCAAGGGTAGAACCAGAAATTAATAATTTAACAGTA TTAGGATATTT

TATTAAAGAATAGATATGGATGGTGAAATAACATTGACAAGAACTTATTCTGGTGAA GATATTGATGT

TTTAGAGGGTCTAGAGGCTATTCAGGTTAGACCGGATATGTATGTAGGAAGTTCAGA TGAAACAGTCA

ATCATCTTGTTAAAGAAGCAATTGATAATGGTGTAGATGAATTTCTTAATAATTTTG GAACAAAGGTTA

TTGTTGACTTAGATACTGACGAAAATATTATTACAGTTATTGATGATGGTCGAGGAT TACCTACTGACA

TTCATCCTAAAAAGAAAATTCCAACAATGCAAGTATTGTTATCAGAAGTACATTCTG GTGCAAAATTC

CGTAAAGATTCTTTTAAAGTTTCTAGTGGTAAGAATGGCGTTGGTATTAAAGCTGTT AATGCATTGTCT

GAATATCTCCGAGTAATTTCTATTAGGGAAGGATACCAATATTCAATGGAATTCTCT AATGGTAAAGTT

ACTAAAGAATTTAAGAAAGAAAAGCAAAAAGAATACAAAGATATCAAGCATGGAACA ATTATTGCAT TTAAGCCTAATGGAGAATTTATCGATAATTATGACAAATTTGATCCCGAATTCATTAAAG ATAATTTAG

AAAAGCGTGCATACAGTAATGCTAATCTTAAATTAATCTATAAAGAAAAAGGTAAAG AAGTAGCTAC

GTATCATCATGAGAATGGTATTCGAGACTATATCACAATTCTTAATAATAATCCTTT TACTAGTAATCA

TTATTATAAAGAAGAATTAGAAAACGGCGACTTATACGAAGTAACTTTTGGATATAG TAACTCTTCAG

ACGAAAATATCTATAGTTTTGTTAATGGATTGAAAACTGCTCGTGGTACGCATGAAA CCGGATTCAAA

ATGGCACTTACAAACTTAATGACTAATTATATTAAGAATAATAAAATGTTGCCAAAA AATATGCAAGC

TAAGGCTATTACGGGTGAAGATATTCGTTCTGGATTAGTATGCGTTATTAATCTTAA GTTGCAAAAAAC

ATCATACAGGTCACAAACTAAAGATGAATTATCAAACCCTGAAGTTTCTGGTATTAT TAAGCGGATTA

CAAATTCAGCAGTAAAAGATATTATGGATACAAACCCTAGTGAATTTAAAAAGGTAT GTAGTCGTATT

ATTGATTTTGCTAAAGGAAGAATTAATGCTTCTAAATATCGTGAAAAGATTGTTAAA GATACGAATAA

TCTTACATTAAGTTCTAAATTTTCAGATTGCCTTTCTAAGGATCCTTCTGAAAGAGA AATCTTTCTATGT

GAAGGAGACTCTGCAAGCTCTGGAATTAAAGAATTCAGAATCTCTCAAACTCAGGCA GTATTCCCATT

AAAAGGTAAACCTAAGAACTCTTATGGTCTTTCTAGTAAAAGTTTATTAGGTAATGA TGAATTTAATA

ATATCATTAAGATTATTTTTGGTACTAATGATATTAAAAATATTGATTATGATAAAG TCCGATATCATA

AAATCATCTTTACTGCAGACGCAGATACTGATGGATTACACATTAATTCATTATTAG GGTTATTCTTTT

ATACGCATTTTAAAGAATTATTTGATAGAGGATATATTTATATCGCAATGCCACCTA AATATAGTACTT

ATGATAATGTTTCTAAGAAATTTATTTACTTTAAGAATGATAAAGAATTAAATACTT TTAAATTCAATA

ACATTAAGAAACGTATTAAGCTTAGTGATGATAGTGAATTTAAATTAAAAGACTTTA TTAATAATATG

AGCGAATATCAAAATCAGTACAATATTGTTAAACAGAATAATAATAATATTTCCGAT AGCGTTATTGA

TACATTCTTATTACATGGTCATGAAAGTAATTCCTTTATTGAAAAGATCCTTCTAGA TAGGAATAACTA

CAGATTCAGTAAGAATAAAAACGGAAATATTATTGGAATGCACGATAATGCTTGGCA TGATATTAATA

TTGACTTATTAAATAATGATATTAGTCGTATTAAGAAAGTTATGAGCATTAGCGACT TGTTTGAATTTA

CAGATACCAAAACAAATGAAATTTATAGTAATGTAACATTAAAATTTCTTATGGATT ATATCAATAGT

AAATTTACGTATAAACTTAACTATTTTAAGGGTCTTGGTGAAGCAAATCCTGAAGAA TTGTTTGATACT

ACCATTGATCCTGAAAAACGTGATTTAATTCAGGTTAGGATTGATCCTGAAAATGAA GAATCAACCCA

AGAAATTACAGATATATTCTTTAAAAATAATTCAACTCAAAGAAAAGAATATGTAAA TAGTTGGTTTA

ATATTAAATAAAATTTTATACAATTCGGGTATTACTTAGAGTTAATCCCGAATTGTA TAATTAAATTAA

AATAAAGGTGGTTCATACTTTTGGCTATTATTCAAAAACAACTTGTAAATATTCATG AAGAAAATATG

GAAGAATACTTTGTTGAAATACTTACTAGTCGTTCAATTCCAGATATTAATGATTCA TTAAAACCCAGT

CAACGAAGAATTATTTATTCTATGAATAAAGATCGAAGATTTAGTAATTTACCATTT ACTAAATCTGCA

ATGATCGTAGGTTCTGCATTAATGATTCATGCCCATGGTGACGCATCATTATACAAT ACTGCAGTAAAT

TTAACTCGTAAATTTTCTAACATGCAACCATTAGTTGAAGGTCACGGATCTTTTGGT AACGTATATGAT

CCTAGACCTGCTCAAATGAGATATACTCAAATGCGACTAAATAAGTTTAGTGAAGAA GTTTTACTAGA

TAATATTAATGATAACTGCGTTGATTTCGTACCATCTTATGATGAATCTGAATTAGA ACCTGTCGTTCT

CCCATCAAAAATTCCAATGATTCTTATCAATGGTTCTTTTGGTATTGGTGGAGCATA TCGTTCATTTATT

CCCCCTCATAATCCAAAAAATGTTATTAATTATACAATTGATTATATCAAAAATCCA AATAAATCTGAA

GAATCATTAATTAAAGATAATGAATTATATCCGAGTTTCCCTCTAGGTGGTATTTTA GATAATAAAGAT ATTATTAAAAAATATACGACTGGTGAAGGAAAATTGGTTCTACGTGCAAAGATTATTAAG GATGAAAA

TAAATCTACTCTTACCATTGTACAATTACCATACATGAAAACTCAAGATATCATTAT TGAAAATATACA

AGAAGCAGTTAAAAAAGAATACATTAAAGATATTAAAGGTATTGATAATGGTTCTGA GCGTGGTAAG

ATTAAACTTATTATTAAATGTTTTAAGGGAACAGACCTAAACGTAGTAGAAAGTCAA TTATATAAGCA

TACCGGATTGCAAAGTACGTTACCATTAAGCTTTGTATTAGTAGATCAAGGTGACTT TAAAAAATATA

ATGGAATTAAACATATTATTTCTGATTGGGTTGAATTTAGAAGAACAACTATTCGAA GAATTAAAACG

AACCTTATTAGTAAACTTGAAAGAAGGATTCATATATTAGAAGGATTACTAAAAGTA TTAGATCCAAA

AGTATTAACAAAACTTATTAAATTAATTCGTGAAGGAAATAGTCGTGATGGAATTAA ACTAAGTATTC

AAGATAAGTTTGATTTATCTGTAGAACAAGCTGAATATATTGTTGAAATGAAGATCT ATCGACTAAGT

AATATTGGTATTAATGATACAAAAAATGAATTAGCTGATAAAATGAGGGAATTTGAC GATCAATCCGA

ATTTATGAAAGATCCTAGTCGTATCGATAAATATATTATTGATGAACTACAATCAAT CAGTAAATCTAA

AAATCTTCGTAATGACTTTGAAATAACTACTTATGATGATAATATGAATGAATTGGA TATCGAATCCCT

GATTCCAGACGAAAATTATACGATTGTTGCTACAAAGGGAAACTATATCAAGAAATT CATTTCAGAAA

TGAAAGTACAAAAACGTGGCGGTAAAGGAATTAATATCGGCAAACTTAAAGATAATG ATATTCCTTTA

GGAATTATCTCTGCTAATAGTAAAGACAATATTTTATTTATTACAGATAAAGGTAAG ATTTATAACTAT

AAATGTTATAAATTACCAAACGCTTCTAGTATTAAGACGCTAGGTAATAATATTTCT AATCTTATTAAA

AAGGAAAAGTTAGTATCGATTATTAGCGTTACTGATGATCAATTAAATAATGATAAA AATTGCTTATT

AGTAAGTACTATTGGTAATAATATTAAGTTAGTATCAATGACCGAACTAAAAAGTAT GAATGAATCTG

GATTAATTTTATCTAAACTTAAAGATAATGATGAAGTAACAAGTGTTAAATTAGTAG ACATTACTGAA

TCTAGTAATGTAATTGGTATCACTTCTGAAGGTATGGTTATTCGTACAGACATCTCA AATATTCCAGTT

ATTAAAAGAACTACACAAGGTAGTAACCTATTTAATAATAAATATATTACAGAAAGT AATAAACTTGT

ATCGGTATCTCTAGAAACAAAAAATACTACTGGTCTGTATATTATTACTAAATCAGG ATTATCTAAACG

TGTAAAGATTGATGAATTCAGTAAATATCCTAGAAGGGTAAAAGGTGTAATGGGGAT TAATCTAAAAG

ATACTGATGATAAAGTTGTATCTATGGAAACTTATGAAAATGTAGATGACCATAATC TTATCATTATCT

CAAATCAGAAAGCAATTTCCATACCTCTTAGTGATATTTCTGAGTATAAGAGACCTG CAAAAGGACTA

ACACTTCAGAAGCTTGAAGATGACAACTATATTATTGATTCATGCTTAATTTAGTAT TAGAGGGTAAGC

CATTGTTTATTGATGGCTTATCTTTTTTTTTTTTTCATTTATATATAAAAATTAACC TTTTATATAACAAT

ATTATATACTATTGAAAGGTTGTGGAAAATAAATGGCAAAAGAACTTATTTTAGATG TTTCTCATCATC

AAGATCCCAATAACTTTAACTGGGCTAAACTTAAAGATGAAATCGATCTAATACTAA TTCGTGTACAA

TATGGATCAAATACTATTGACCGTCAATACAAGAAATTTGTTGAGCTTGCTAAAAAA CATAAAATTCC

TTTTGGTCACTATGCTTATGGTGTATTTGTTAGTTCTAAAGATGCAGTAGTTGAAGC TAATAACTTTTTA

AAACGTGGTGATAGTGAAGCTACTGTATGGATTTTAGATGTAGAATCCGACACTATT GAGTCATGTAA

AAATTCTCCTCTAGGTGAAGCTTCTCAAGCATTTATCGATACTCTTAGCAAAGCCGG AAAGAAAACTG

_{GTTTTTACTATGAACATCGTTATATTGGAAAATATGGTTTAGATAATGTTAAAGC TGATTTCCGCTGGA}

TGCCACGCTATGGAAAAAATGATGGTACTTTATCAGGAAGTGCTAAACCTGATATTT CTTGTGATTTAT

GGCAATATACTAGTACTGGTAAGCTAAAATCATATTCCGGTAGTGCTTTAGACTTAA GTATTCTTAATG

GTAAGAAGGATATTAAATACTTTACAGGTAAAGCATCATCAAATAAACCATCCACTG TTAAACCATCT AAGCCTTCTAAACCTAGTGATTCAAAAGATACTGTAAAAACTACTAGTTATTATGTTACT GCAACTAA

ACTTAATATTCGTCAAAAACCTGATGCTGATAGTAAATCTTTAGGAACATTGGATCA TAATGATCGTGT

TCAAGTTATTTCAATTAGTAAAGGTTGGGCAAAATTAAAATCCGGTAGTAAAGAAGT ATATGTTTCTG

AAAAATATATTTCTAAAAAAGCAAAATCAAATAAACCGAAACCAGTAACCACTAAGA CTTATACAGT

CGTAAAAGGGGATACTCTTTCTGGTATTGGCAAAAAACTTGGAAAAGATTGGAAAGC ATTAGCTTCTA

AAAATAATATTAAAGGTCCAGCTTACGTAATTAAACCAGGACAAAAAATTAAATATT AAATATTTTAT

TCACCATACAAACAGATCATTATATTTAGTGATCACATATGTTTGTATGGTGATCTT TTTAAGAAAGAG

GGTTTGAAAAGTTGACTAAACAATCAATATTATTAAATAGTTTTGAAGAAAAAATTG AACAGGCATTT

AAAAATAGTAGTAATGTAAATAAATTAGTAAAAATTGTAAGTCAATATATTGATAAA AATAGTGATAT

ATTAAATCATAATACACCTACATATCGACTAGTGTTTGCTCGTGAAGGATATGATGC TGAAGTTATATA

TGATATAGTTAATATATATCCTGAAGAAATTAAAGAAGTTATTTCACAACTAACATT TATTCGAAAAG

AATGGAAAGTAACCAATGAACCCTTTTCGGTATTAATGACTTTAATTATTCGATATT TTCATTTAAAAA

ATAATCGTAGAGCATTGCAATCTGCAATAATGTATCTTTCATTATCATTTTATTCAT CGTTACATTTTAG

ATCATTTAGATATGAACCGAACGATAATATTATGCAGTATACAATTAACCGTGTAAG TAATAAATTCT

ACTTTAAACAGTACGGTACAGTATTTAAAGCACTTAATGCTACTGCTGACAAAGCAG ATATGAATCTT

AAAAACTCTTTAAAAAAGAATGATGACGAATTAATTATTGCATATATGACATCCCTA AGAAGTCGTCT

TGCAAACCAATTAACTACTTTTGCCCAAGAGTTTTATAAAGACCATGCAGCTAATAA TTATTTAAATAA

GGTATCGGATGTTTATGATGACGAAAACCATATTGAAAATACAAATGTTTCTGGAAT TGTGATGTCAC

AAACTAGTAAAGTATCTCTTAACTTTTATCAATCTAGACTTAATGAAAAATATATTA TGATATCTGCAT

CTACTTCTAAAGTTACGGCTAATGCAGTAAGAAATACATTAGAAGATGTTAAGGAAC ATGAACGAGA

AAAAGTGGAAACGATTATTCGTAATACAATATCAATATATTTAAATGATCGAAAAAA TTCGGTAAACT

CAATCGGATCACAGAAATTTATCAATTATTGTATTGGAATATATACAAAAAGTAATA CAAAAGAAAAA

TTGGTATTAGAAATAAAATCAATATTAAACTATTTCTTAAAAGAATACTGTGATAAA TATAACAGTAC

TGATAGGGAAGCTACTAAGAATAATTATCGTAAAGCTGTATTTCTTTACTTTATATT CTTAATCAGTGC

AAATAACTAAAAAAAAAAAATATTAAAGAATATATCCATATAACCAATAATAGGTTA TATGGATATAT

TTTTATTGCTTATTTAAATTTCTTCAGTATCCCTTTTTATTAATTCATTTACTTTTT CTGATATAAATATA

GTGGATATTCCCATTGAAATCATTGTAATCAGCATAAGTGTTAATAACGCTAAAATT AAAATTTGCATA

ATAATCATTATAACCATCCTTTTAAATTTTATTTTTCAATTACAGTACTTGTAATAT TACCATCAGTATC

GACTCCAGTCATTACAGTGTATGTATTAACTACAGCACCCTCTGCAAATACGCCATC AGTTCCTTTAGA

TTTTACAAATACAATGTATGTATGTTCCCCATGAGGACCCATTTGTTCATTGTCTTC TGTAATATCATAA

TATAAATTACTAGTATTAATATTTCCATATTTTTTAGATACAATTGAAGCTAGATCT TCATTAGATAAT

GTTGTTGACATATATACTTGTTGATAATTATTTAGATCAACTTTTTTACTATTTTTT ACTTGTTCTTTCAT

TTCGCTTAATTTACTTTGTTTATAATCTACTTTATCAATAGATAATGTTTTTGATTT AGTGTTATATTTAA

CCGTTTTATCTTTAATATTGAAAATAAGATTTCCATTTTTATCATCTTTAGATTGAT ATTTGTCAAATTT

ATCATTCAATACTACATTATCATCTACATGACCGATTTCAACGCTAGTATAACTACC TAATACTAAATG

ATCTTTAGTTAATTTTACATATCCTTGAGTATCTTCATTATAATATTCCCCAGTAAC TGTATTGATATCT

GGAGTCTTTTCTTTTTTAATTGTTACTTTCTTTTCTTTTTTCTTATTTTCTTTAGAA GGAGTTTTAGTTTCA ATTTTCTTAACGTCATTATCTTTCTTTACAAAAGTATAATTGGTTGACACAATCCCAACA AATATTCCA

AGGGCAATAGCTACAGTAATAATTCCAGTTAGTATTAATTTCTTTTTCATGTTGATC CATCCTTTTCTTT

_{TTTTTTTTATTTAAATGTCTAATACCGAATAGCTAATCGATATTAGACATAATTG AAAATTTATTATTTT}

TATTAATTTTTTTATTAATTAAATTTTGAATTTTAATAACTTCTTTTTTAAATTCTA AGTTTCTATCATCT

ATACCTTGGATAACTTTATCAAATTGATTATATCCAATAATATTTACATATCCTTCT AGACCAGAACCT

TTTATATCCTTATAACTGGATATAATAAATGATTTTGCATTACTTTTTACATATAAA TTTGAATTATATG

AATTATTAGTTTTTCTAATTTTAATATATGATGATACCATTTTCTTAACTTGTTTTT CATTCACAAATAA

TACTTTATATTTATCATTGATATATACTTCTTCAGGAATAATTCTTCTTTCTAACAT GTATGGAACACTT

TTATTAAATGTAATTTCTGATGTATCATTATTATAAATAATATTATCATCTTTACGA ATATTAATATATT

TATCAATATCTTTTACAGTATGAACTGCAGATAACTTATCGAAATTAATATCAAATT TTTCCATATAAA

TATAAATATCTAGTTCACCGCTAATATATTTACCGTTATCATATGTGATTATAGATA CGGTAGTTTTCGT

AGTTCCATTAAATTCAGATGTTTCGATATTATGCGTATTAAGAATTATATACTTAAG ATTATTATTATAT

AATTTTTTGATCTGTAAAAATAAGTCATTTACACTATACATTAGCATAATAGTTAAT ACCAACTTCCAT

TATTAATTTTTAATACTAGGATAATATCTATTAATTTAGATATTATCCTAGTGATAT TTTATTAATCTTC

AAATACAACGAATCCGTAGATATTAATTGGATCTTCTACTTCAGTAATTACACTAAA TGTATTTCCATT

AGCACCACCATTATCTTCTACTACATAACCACTGTGACCCATCACTTCAGTAATATT ATTATCCTGTAG

TTCTTTCATCTTACCATCATCAAAAAAGTCAGGATCAATTTCATCCACCCCTAATGT ATAACTTTCTGA

AATGACTACATCTACACCATACACTTTTTTAATTTTTTCCGTTAATTTACTTACGTC TAATGACATAATA

AACACTTCCTTATTATTTATTTTATTTCATGATTATAATATATATTTGTAAATGTCT TTATTACGGATTA

ATCGATATTCTTTTCCTTCAATAGTATTTATATTTAATGACATAGGATTAATATGTG GATGTAATACTAC

ACGTTTATAACTGAATACCTGATTCATAAGTTCAATAATATTGTCAGCATCAAAATT ATCGTTTATATA

TTCAATACTGTATATAATATTTTTATGCATTGAAACATTTAAACCAACATCAATATT ATTCTTATCTAAA

TATTCTTTGATTAGATTAAGTCTATTTACGATATCATATTGGTCTGGAAAACAGTTC ATTAAATGGCTT

GCCCTTCCTTGAATATTTTCTTCAATTATCATAATTTCTTTTATTTGTTCTATTATA TTATCCAACTAATT

CACTACCTTCTTTTAATATATTTGATAATTCTTTATAATATTTTCCTTCCAATGTAG TAATAATATTATC

ATCATTGTCTAGAAATATTAATGAGAATATCTGGCAACTATTTCTTGCAATAAATAA TTTATTAACTTT

TTCACCTTTTTCTAAGAATGTATTAAGTTTAATATCATAATACTTATAATAAAGACT TCGCATAATCCA

ACCAATATCACGTTCTTCTTGAATATATAATGTATCGTCATAATCTGGAATAATATC TAATTCATATAT

TTTTTCTGAATCATCATAATTGTATGAACTAAACTTATGTTCACTATTAATTAAGGT ATGTGGTCTATCA

AAATAACATTTATCCTCTAGTATTGTACGATTAATATCATTACGTAAATATCCTAAG AATATCTTTTTAT

AATGAGTATTATTAGTAATCCAATCCGAAATAATACTAAAATCATTATTATTTAATA ACTGGTTTGATT

CAATATTATCCATTATTAAACAAATATCTATAGTTTTTGTTTCTTGATTGAATATTC CAATTTCCCATAC

AAAACTAAACCAGATCTTTTTACCCATATATCCAGTCAATATTCCTGCAAGAGGATT CTCTAGAGATAT

TTTTACTAAAGGTGCAGCCAATCCATTAGGAGTGAAACAACATTTTGTTTTAACGCC AATATTCATTAT

TTCATCAACATCTTTAGAAAAGTAAATAAATTTATTACTATGATTATTGGATATATT CATTTTAGATTC

AGATACATTATATTTTGTACCTGCACGAGCCAATAATACATTATTGATATATTTATT CATTTCCTTATAA

TTTAGGTCAGATTTTCGAATTACTTCATAATTCATAAAAGGTAATAATTTAATAAAC TTATCATTATTA TATTTAGATAATGAACTTTGAAGAAAATTATATGCTTCATCAATATAATTACTATTTACT TTTTTATTTG

TAATATATTTATTAGTAACTTTATTAGGAAATTCACTAACAAATCGATGAATGGATA TATTATTGACTA

CGCATTTATTTAAAATATTCATTAACTGTTCATATGAAAATAAATTAAACATACGAT ATAAACCATTTT

TCTTTTTATATTTAACAAATTGTATGTCAAATAATTCAGGTTCTAATTTATTATCAA GATTATTATTGTA

CCAGTCCTTAATAAGCTTTATCATCTTATACATTCTTTTTTTACCAAACTTATCATG CAAAAACAGTATT

TCATGTTCTAATTTAAAATCAGTAATTGAAGCACCAATACCAATATTTAATTGATGT AATTTTTCAATT

ATTTTAATTTCATTATAGATTTCACTGTCAATTTGAGAAAGTGAAAGTACATCTTTA TATAAGGATGCA

ATATATTCTTCATATAGTACATTATTATTCTTCAATTTTTTCATCACCACGCTTTAT AGATTCAAATATA

TTAATATACTTATCATATAATTTTCTAAATTTTCCAGTTTCATCAATATGCAAATAG TATGACATCTTAC

CAAGTAATTCATAATCATCATAATAACAAGATCCGGTTTTCATATATGAATATAAGT TATTACGCATAT

CATCATACTTTTCTGAACTTAATGTTAATTGATTTTTATGATTTATCGTAATCCCAG TAATATTACGCAT

ATTCCCTTTAAGATAGACAGTTTTACTATCATTAATTTTAAATTTATCATTATATAT CTTGAATGCCTGA

TTACATATCTTAATGATAAATTTTTTATTAAATAGTTTATTATTGTCAATATTTGTT GAAAAAGTAATAT

CATCCGAATATGAAGAACAAATTATTCCATATTTATGGAATATGGTTTGTATATGAT TAATAATATCTA

CCATAATAATATTCGATATTACGCCAGAAACTGGATTACCTAGAAACATTTTATCAT TTTCATCAACAA

AACCTTTCTTTATAGTATCCATATATTTATCAGTAACGCCATGGAATAATAGTAATA TGAATCTACTAT

TAATTAATTTCCAATCAATACTAGGAAAATAATTAGATATATCTACTTTAATAATAT ATTTATTATTAA

GGTGCATTAATGCATTATCTTTTATAGATACATTTTTTCGATAAGCCATAATATTTG GATATTTCAAGTT

TGATATTTTTCTATCTAATCTTTTATCGAGGATCTTAGAAATTTCTTTTAATGTATT TTTAATTTTTATAT

TTGGATCAATAACTTCACGTTCTTTACCATTTTTTTCTATCTTGATTTTCTTAAATA ATTCAATATTATTG

TCCTCTAAGTCTTTAATGATACAATATAACTGAATTATTTCTAGAGACATTCTTCTT TTTAATAATAATT

TTATATCACTGGCATATTTACTTTTAAGTTTATAAATTAGATATTTACTATTACTAA TTTTAGAGTTGGG

ATATAATAATATATATCCTTTACTTACTGATACAAGAGGTGTAGATGAAAAAGATCT ATACATACTAA

AGAATTCACTATATTCCCTCAGCTCAATAGAATTCTCTAATAAATATTTTTTACTAT AGTTAAAATCTAT

ACTGTTGGATGTCTTATAATAATTCATAATCTTAATTAATAAGTCATAACTATCCTT AAATAGTATATT

ATTTAGCTGAACTAACTTTTTTTCTGAATTATCAAATCTTGATATTATTTTAATATC TTTATCATATGGA

TAAAAGATCCCTTTATTAGTTAAAATTCTTAATGGATTCTTACTAATTATTAATAAA TCATTCAATATTT

ATCTTCACCTTTCTTTTTATTGTTTTCAAAAAAATTTAAAATGACCGAACATTCTTT ATACTAATAATGT

ATAAAGAATGTTCGGCTAGTATATTTTAGATAGATGTATACTTTTACTACTCAAATA TAATAATACAAA

TTACGTTAGTACGAATATACAGTATACCGCACGCGCTGAGTGCGGTATACTAACACG CAACCGAAATC

TATGAGGTGCGTGTTAGTATAATTAATATTACAGAGAATAGTGTTAAGTGTTTGAAT GCATATTAACG

ATACGTTAATGCTTCTCAAATATTAAATGATATATTGAGAAAAACTAATATTATATT GATAGCTTAATA

TACATCTATTAAAACCAAAATTATATTATATTATTTACATAAAATAATAATTTTTTA TTATATATAAAA

TCAAAAAACAGGAATTTATTGACCGGGGTCCGAATAATGTCGATTTATCGCATGAAT GGACCCGAAGC

AATAAATTGCATGTATAATGGAAATAATTTTTTGACTAGTGACGATTACATCACATA TTAATCATTTTA

TATATAATATATTAACTTATAAATTGTAAAATCCAAGAAATTTATGAAACCGCAGCT CACGTCCCGAG

TAATTTATAACTCGGAAATGTGAGCTGCTGGTTTTACTAAATGATAATGATAGAGAC TTTTTTGATTAG TGACGATTACATCACATATTAATCATTTTACAATTTATAATTACGTAAATTAAATAATAT TTTGATTTAC

TGATTATTAATCAGTCTAAAATATTCCTTCAATATAATGATATATACTTAAAATTTA AGTAAACTTTAA

AAGCATATATTTGAGAAGGATACTTATAATTAATAGTAAATTGTAGAATCTAAACAA AAGAATTCAGC

ACTTCATTCGTACCTGACGTAACTAGTAAGGCAGGTACGGAAAGGATGTGGAATTAC TTTAATAATGA

TAGAAACTTTTTTGATTAGTGACGATTACATCACATATTAATCATTCTACAATATAC AATAAATATTAA

AATTTAAGTAAGATTTAAAATCAGTGAAAAGATTTGTGAGATGTCGGATCGGATCGA GAAATACTTGT

ATGAAGCGATCAGATACTCTGATATCAAACAATCAATAAAATACGACATATATTGAT TAGTGACGATT

ACATCACATATTAATCATTTTATATCTACTTAAATTTATAAATTAATAATAATTTTT GCATCTTCTTTAA

TATTAACACTTTCCGGTCTAGAAGTTTTTAGAGAAGTTCTATCATTAAATCGAGTAT CTTTAATAAATT

CTAATCCATCAATATTAATTCTTTTCATAAACTGTTTAGAATTTTCATTAAATGATG ATGAAATATATTT

AATGTCATTATCAATAATAAATTTCTTTAGATCTTCAAAAATATACTTAATACTTGA GGTAATTTTTTTA

TTAAATGGAATTACAATGTCTTCAATATACAATAATTTACTATGGGTATCCGTATTA AAGCTTCTATTG

TTAAATTGAACGCTCTCATTTTCCGGATCATAACCATAAATATTAGATATTAAATAT CCATAAATATCA

TTGTTATCATTACGAATAATATATGATGGAGACTTCATTTTCCTAGCAATTTTCTTT AATTCAGAAATAT

CGCTATCTTGTTTCCAAACATTCTTTTCAACGTATAACATTCTATTGAACCAACCCG GTGATGCCTTTTC

AATAATAACTTCACTATATGGAGAATATTTTTTAATAATATCTTTATTATCAGAACC AATATATTTAAT

ATTATTTTTACGATCTAATACCGTAAATACATATCTTGAGTCGTCAAATGATGAATA TCTATTGAAGTT

ATTTTCATAACAAATTAGCCCTTCACTAGAAGATCTTAATCTCTGAGTATATGAAAC TTTATAATTACT

ATTAATATCATTACGTAAATATCCTAAATATATTTTATTGTAGTCTGAATTAATATC AAGCCAGTTAAT

AATATATTCATATTCATTCATGTCTAAACTTTTTGACGATTCAATATTATCTAGAAT TAAATTGGTTTCA

TATGATTTAGTATCTTCATTATATTCAACAATCTCCCATACAAAACTAAACCACGTT TTAGTATCAAAA

ACGCCCTCAAGAATCCCTGCGATTGGACTTTCAATAGCGGGTTTTAATAATGATTTT GCAGCACCGTCT

GGTCTGAAACAACATAATGTACGGAAACCAATTGAATTAATGTCTACTTTTTCTTTA GTAAATTTAATC

ATATCATTATATTTACTATCGTCAAATAGCATTTCACCATTAGAAGTTTCCCCATAG GATAATCCTTTTT

TTGCGTTATCAATAATATTAACATACTTTCTTAGATCACTAATATTTTTAGATTCCC TAACACCTTGATA

ATTAATATAGTTTAATAGCTTAAGAAAGTCTTTACTTTTATAAATTCTTTTAATATA TGCTAATATCGTA

TCAATATATGTTTCATCATCATCCAGTCTTTCTATTGCAGTCTTTGGAAAATTCTCG ATAAAGTTATGAA

GATCTATTTTATTTTCAGAATTACCCTTATTATATGCATATGAGACAAAATTAAGAA GTTTAGTTGCAT

TATCATATGAGATTCGAATTAATAATGAATTTAATTTACTTCCATAATTACTATTTT TTTCTTTAAGATT

TGATATAGTAAAGTTACTAGTATACTTATCCTTAAACATTTTTGGATTAATACCTAA ATGTGACTCAGA

TATAAGATCTGTAATTTGGTAAACATCCTTTAATTGTTTAACAGGTTCTACTAGATT GATATTACTTCTT

AAATCATTATTTAATTTATTTGTTATTTCTAAATCCATATTAAATTCATACTTATTA ATGCGATCACTGA

GAATACTATCTTCGCATGATAACATTAGCTTCATAATATTGATTGCTTTTTTCTGAC TGTTATATAATGC

GGATAGATATATTAATGCACTAGTAAGTCTTTCACTATTGATTAATAAAAATTCTGG AGGAATAACTCT

AAATCTTCCAATGTCATGTAAAGAAGTAATATTATTTATTACCTGTAATAGATCAGA ATTATCCATTGT

ATAGTTAAATTTAGAACAATAGTCTAGAAAATTAGAGAATATTTCATTTATTCGTTT AGATAATTTTTC

ATCATCTATATTATTGTAGTTGTCATATAAATACATATTATGATTCACTTCCTTATT TATTAATCAACTT TAGGTTCATTAATTAATTTTAATTTAATTAACGTATTTTGATATTCATTTACGAGATTTT CCATTTTATT

AGTATTATCGATATAACGATAATAACTAATTCTACCTTTAAGTTCATTAAATGTCAT TGAAATATTATT

AATATTATTTTTATTCTTAGATAATTTAAAGAAAATAGTCTTTAGTAGTCTATACAT TTTCCTATCTAAT

GTACATTGATCATTGTGATTAATTCGAATCCCTGTAATTCTTCTTTTGTTATTCGAC ATTTTAATAGTTT

TTTCATCTTTAATAGATAAATTACTATAATTATATACTTCAAATGCCTTATTAAGAA TGAACTTCAAAT

ATTTTCTATTAAAGAATTCACTTTTCTCGTTTGATGAAAAAGTAATATCATCTGCAT AAATAGAGAATG

TAATACCACTATCAATTAATACATTTTTAAGATATTTTGCCACATTACTCATTAACA AGTTTGATAATG

ATCCAGAAGCAGGATTCCCCTGATATAATCCACCAGTCTCTGGATTAATAAAGATTT CTTTGAATAACG

TATCCATTACTGAATCTTTATTATTCTTCTTCTTAAAATTTTCTTTACCTAACACTA ATAATTTAAAGTA

CTTACTAATATCTTCATATCTACAATTATCAAAGAATGAAGCAATATCCATTTTAAT AATATATTTATT

_{ATTTTTATGAACTAATGCGTTATCTAGTATACCTTTTTTCTTTTGATAAGCAAAT AAATGTTTTTCAACA}

CCTTTATTAGATAATTGAGTTTCTAACATTCCATTAAAGATATTATTAAATTTTCTA CTAATATCTTTAA

TATCATTATGTGGAGCATAGATATCTCTAATTTTTGTACCTTGATTAATCTTGAAAT GTTGATATAATTT

TTCATTATTATTCTGAATTAATATTCTGGTTAATAGTAACTCTAGTAATAATGGTTT ATTATTTGGTTGA

TCTGGCGATATACTTATATCTAATAAATATTTAATCATTTTAATCATTTCTTTATCA TCTGTGATTTTAT

AAATATTATATTTATTGTATATATCATTTGTATTTGTAATAATATAGAGATAACCAT CATTCATTTCAAT

ATATCTATGAGATATATTGAGATTTCTATAGGATAATTTTATACTGATATTATTAAT AAACTCTGTAAT

TAAAGTTTTATCATAAGTAACAACTGGTAAATCGGGATATCCTTCATTAATACAAAT TTCATCATTTGA

GAGCAGATCATAAGTCTTAATAATTTTTTCTATATTTTCTAGATGAATGTCATTAAA TTCCTCGTTATTT

TCAAATTTATTATTTTCTTCTAGATATGATATATCTTTTATTGATTGAATCAATTTA TTACGGATATTAT

ATTTAACTAATTTAGCTAATACCTTTTTATCAGAAATAATATTCTTTTTCATTCGAA TATCTATTTCTGA

TACAATCTCTCCATTTATATCGATTAATACATTATCGATTAATATTAGTGATAGCAA ATACTGTCACAC

CTTTCCTTTAATTATTAAATTATTACTACATAAATTTACTATTTAATATTCATTATA TGATCCCACCTAT

TTATTTTATTTTACATTTTAATAATATATAAATAAAATTTAAATAAATATTCCCGAT ATCTCTATAATAG

GAGATATCGGGAATATATTTTATTTAGTTACAGTTACGTTAATTTTTCTTTTCATGG AAGTAAAAGATT

CAGGAACAACGGTAATAATTGTTTCACCTTCACTTACGCCAATAAGTTTAGATGGAT TATTCTCATCCA

CTTTAACGAGTTCTTCACCTTTTTCTAGAATTATCAGAACCTTATCACTAACGAGAT TATCAGGAGTCA

TAGTTCCGATAATATCTTTACTTTCGCCTTCTTTTATAGTAAGATCTTCATCTACGC TAAAACTTTCTGG

TTTGGTAATTCTATCGTTAATTACAGATATTACGTCTATAGTATCAATAGGTGTATA CCACGAAGAAAC

TTGTCCTGCAATACCTCTTGATTCATCTACTACTTCATCATAAATGATACAACCGCT TACATCATCATAC

GTAAGTCGATGTCCAAAAGCTCTTGATGGAAAAATTTGAGATTGGGATGTTGTTACA ATTGTGGAGAT

TAATAGTGGATCAGATAAATCATTATGACGATCGATAAATCCTTTTACAGTTTCAAT AGCTATCATTTT

TATTATTCATTCCTCTCTATTTTAACGAATATTTTTTCTGCGATTAAATTCAGCTTC CTCTTTCTTTTCAT

TAAGGATTGTTAGATGAGTATCTATTCTATCTTGCTTTGCTTCCTTATCACTTTTAA AAGTATTATTGTT

AATAATACTTTCACTAAATACGTTTGGATGAGATATATTGCTTTTTTCATTAAATCC ATCATTGAAGAA

AATACTTTCATCAATATTTTTATTATCCATATTTATAAACATCCTTTCCTACATGAT TATAAACCTTCAA

AGAACTTCCACATATTCTCATCAACTTCTCCAGTAATAACCATATTAGATACCATTT GTATTTTTCTTAC ATTATTATAAGTATCCTTATCATATATTCCTGAAACACTAGTTGTTGTAATTGCAAATTT ACGTTTATTA

TCATTTATCTTTGTTTGAATAAATAATACGTCTGGTCCTTCCATAAGAGGATTACTA TATTTAAGAACT

CTTGTAAATTCAACAATAAGCGTATCAATAATATTTTTCCATGTTATGGGTCCAACA ATTCCATCTTCA

GTAAGATTATTTGAATGTTGAAATGATTTAACAATAGTTTCAGTAGAACTATCATAA GAACCAGTAAC

CTCAATATCATATCTTAGTTTTGAAAGTTTATTTTGAAGCGTAATAATATCGTCACC TATCATCATTGGT

GATTTATAACTAAGCATTCGATGATAGTTTGAATAGTCTTTAATATCATTTAATGCA ATTATCAATTCA

TTAATTTTATCAAAGTCTTCTTTCTTCATTCTACCATCAACTTCTAGATTAAATGTT TTTTGGAATATTCT

TACCGAGTTATATGTGTATAAATCATAGATACCATTACGAATAGTGATTGGGATATT AATCATAGATA

AATATATTTGTAATAATTTAACGTCATTACCGATAACTGGTTTTTCTGGATCATAGT AGAATTCCCTTTT

ACCAAAACTATAAGAAACAGTTCCTGCAGGATTGTCTACATACATCGGTACAATAAT AGAAAGAATTT

GGGAACGAAGAACATTCATATCAACTAATGATCCTAGATTACTATATTTTGCATAAT ATTCATTTAATG

AATGAATGTTTCTAATATTTCGATATCGACCACTAATATTAGCACATAGATTCTCTA GAGATACATATT

GGCTTTGAGTTAGGTCTTTAATCTCCGTATTTCCTTCAAGACATATAAAGATTTTAC TAGAAGATACTG

GATCAGTATTATCAATGAGTTCAATATCTTTTCCAGCAATATTTTCATTAAGATACA TTTTCCGCATTAG

TAAGTCAATATTACAAGGTAATGCTCTTTCGGGTCTACCTGAAATAATATCCCCTTT TTTAGTAATATA

ATAATGGAATGCAAACATCTTTAATCCTAACCCTTTATGAATTGATTCTAATGTATC ATAATCCATACT

AATATTACGACAATCTAAAATAACTATATTTGATGGATTATTCTTGTATATAAGATC TTTTACCGGGTC

AGGAGTTGTATCTACATAGTTCTCATCAGTATTAGCATCCAGTAAAGATAACATGTA TGATATATGACT

TCCCCACATATTATTCCATTGTTTTCCATCTACTGAAAAAGTTCCCGCTAAATCATT TTGATCATAAGA

ACCGCTTCTTGTAAATTTATTTAAGTATCTTAAACAACGGTTTAATAATGAATACGT AGTAGATATTTC

AATAGTGTCATTTATGATATTTAAATAACGGATACACGACTCTGCAAGAATGCTTGC ATAATAGGTATT

ATCTCTAGCACTGTTTGGTTCATATACACTATTAAATTTTGTGATTATCCCTTTATT TTCAGAGTTCCAT

ATAGTATTAATAGATTTTATAAATTTCATAATGATATTATTTACATTATTATTTACG TAACCTTTTTCAA

GAAGTCTAATTAATGAATTAATGATATTATATTGAAACTCTCCCCAATCTCCTCTTT GATCTAAACCTT

CCCACCTAAAACTATTAGATGAAATATCAAAGATAGGTTTAAAGAAACCTTCTACAC CTTTTTCATTAT

AATATTCTTTTTGAGATCGATCTAAAATATCAATAAGTTTAGTTAATTCATTAATCA TTCCAAGGTCAT

ATAATACTTCTGGTTTTTGATAACCTAGATATATGTCATCGTTCCAACTATCAAGCT TATTATTAATAGT

TGTTATTGAGTTAGGTAGCATTATATTTTTCATATTATTAGAATAATTATCAACGCT TTCGATATAATCG

ATATTTATAATACTAGGAATATCTTTTTCCTTTTCAATATAAAACTTATTAAATGTA CGATCTAATGAAT

AATTTAATAATGATCCGATATATTGAAGCTCAATGAAAGAAGAAGTAACCTTACTTT TAAATATTGCTT

TGGTTAATGGAAATTTAACAGATTTTCCATCAGTATTAAAATTAACTTTAATACTAT TAAATAAATCAA

CTGATTTAGGAAGATTTAATTTCCATTCTACATTATTACTATCATAGATATATAAAT CAATTCCATCACT

AGCACGATAGCGAATTGTAGGGTTTGTTTTTGTATTTCGACTAAAAGGAATAACCAT GTTTGACCAACC

ATCATAAGAACCATTATCATTACTTTCTTCATTAATCGTAAAGGTAGCTTTAATACT ATTCCGAGTTTC

ATCATCAGTAGATTTCACTTCAATAATTTCAGAAATACTATTCGGAGAACTCTCTGC AATATATAATGA

TTCTTCAGGAAGATTAAAATTATCCCAGATTACTTCACGGTAATCTTTTAACATTTC AGGAGTCAATCG

ATATTTATTAAATTCATTATCTTTTACATTCGTCTTATAGAATCCAATATTATGATC TTTATCTTCAATA ATAAATTTTAATACTTTATCATTATCGGTTTTAATTCTAGATTCTATATATGAAATATCT TTAAGCGTAA

ATAATTTATTTACGCCAAAATGAATATCTTGATTAATTGAGATTGAATTTAGTATAA CATTTCCATTAG

TATCATCACGATAAATTAATACAGAATCTGAACTATCTTTATTAATAAAAGAGCCAC TATCAGATAAT

GGATCCAAATTATTTATTTCAGAAGTGATCCATCTAGGTTTAATTGGCATATCTAAT ATAAATTTAATA

GTATCTTTTGTAATATCCCTTGCCCTCATCCATTTACTATTCGGTAAAATATCATAA AGATTACTATAAC

ATTCATAAGAAAGCAATAAACTTTCAATACTGCATATATTTTTATTAGGATCCAGAG TATGCCAATAAT

TTGTAGGATCATATTTCTGATTAGATTTAATAAAGTTATCATTATCTAATTGAGTAT ATACTAGTAATA

GCGTGCTGTTAACATCTTTATCTTCTAATACAATCCTTACAGTATTATCTTTACGGA TATAATACTCTTC

AATATCATAGCTTATACCTATAATATTAGAAGCCGGATTATTTTCATCACTTAATTT AGAACCAAAATC

TCTAACACTAAATAATTTTTTAAAATTGCTATCCGTACTAAAAATTGCAATACCATT AACAAATTCTGC

CGATTCATTCAATATTAATTTTTCAGAATTAAAGGGTTCCGATGCATTATATGTAAA ATGAGGAACCCA

TAAATTATCTTGAGAAAAACTAGTTGGAACATCATTTGGATATAAGGTATCAATGGT TGCATTCATCGT

AGATTCTATTAATTCTAAGGATATACTTACGCCAGAATTATACTGATATATAAGTGA ATTAATATATTG

AAACTGCGAAGTAGATGTTCCTGAATTAATATTAATATAATCAAATAAGTAATCTTC TTTTATATAATT

TAATCTAGACATTGAATTAAGATTTATAGATAATGGACTAGTGTTTTTTGTATTTGC ACTTACAAATTT

ATTATATTCAGATATCCATTTTCTAATATCTTTTAAATGAACATCTAATTTCTTTTC AGAAAGATATTTT

GTCAAATTTATCACCGCCATTCATATTATAACATTTTGTTTAATATCAATTTAACTT TTTACCCAACCTT

TAGTATTATTATATTTATATTTAACTGTAGTAATTTTAGTTTCATTAATAACTTTCT TAAGACCTAATCT

TAATACAAGTGAATCCCTATTAATAATATTCCGTGCAGAAACATATCTAACTTGTTT TGTAATGAATGG

AATTGTTCGTTGAACTGTAGAGAATGGACTACTTGAGTTGTCTCTACTCTTTGGTAA TCTTTGAAGATT

ATCAGAGTTAAGCGTAGATATTCGATTAAGACCAGTAGGATCGATCTTCCATTTTTT ACTTTTACCACC

AAGATTAACTTTTTGTCGCCACGTTGCAGATCCTCCACCATACTTAACGCTCGGGTT AGGTGAAAATCC

ATTAGACGATGTAGTAAATGTAGTTTTAGACGCAAATCCTGAAGGACTTTCATATAA TGGCATTAGTA

AATTAGATGGACTTCTAATGTATCCAATAGTATTTGCAGGACTGCTTGTTGTTCCAG TTAATGGCAATC

CTTCAAACATATCCCATGATAAATATCTATTCGATATTCTAGTTCCAGTAGTTTTAT TTACTTTATTATA

GAATCCTCGATAAAATACACCAGTACCTTCAGTAACACTATATTTTTCACGAGTTAG AGGATCAATTGC

CGAACCTTGATAGAACCAATCAGAAAATCTAGATCTTAATCCAACACAAGCATCTAC ATATTGGCTTT

CTGAAGTATAATTCGAACTAGAGTAGTTAAATAATCTTCGATCCCAACGACAATCAT ATGCAGTTTTTT

CATATGATACACTTTTTTGTAATTGCATTGTTCCTGAAAAACTTCCCATTTTAATTA ATTTCTGATTTAC

TTCATCCATAAGTGTTTTAATATTATTCCATATCTGTAATAATTCAGTATTCTTACT ATTCGCATCATTA

CTAAATGCTTCAGTCAATGAATTATTACTAAGGTTATTGAATATATCAATCTGACTT TGTATTAAGTCA

TTATATTGTCCTAAGTCTAGTCCGTCTAATTGTAATGATATATCACCTAATTGGTTT ACATTATTCTTAC

TTATTTTACCTAGATATACTGTTTTGAGTCGGGCAGACTCCATATCAGAAAAAATAT CTAAACTTGTAT

CAAATATTTCTTCTTGTTTATTATATATTTCATTATATATATTATATAAATTATTAA TCTTTCCAGGTATT

ACATTCTTTCTTAATTTTATACCTTCCATATCATTCTCTAGGAAATCAATAATATTT TCTCTAAGAACTT

TAGTAATTGGTATTGGTAAGTTAATACCTTCCTCTGTAACGTATATGTCATGTTCTA CTAGATCAACTA

ATAACTCTCCAGTCTTCAGAGTATTAAAATATTTTTGAAGATAGTCTTGATACGACA TTGGTATATAAA TATATCTTGACATTAAAATTACACCACCATTATTATATAATATGTTTAAATGTTATTGAT TTAACCTTTT

TATTACTTATCTTCCCTTTAGTCTTATTTACTAATGAAGTTACCCATGAATCATATG TTGATTGAAATGC

ACGAGAATCTACATTTTTCTCAACAGTAGTATATCTTGATCTCATATTAGTTAAATC AGTTCCAGTTTTA

GTCTTATAACCTTTTATAAAGTTGTATAGATATGTTAATTCAGATAATCTTCTTTGT ATTGAAAATATTC

CAGGAAGCTTTTCTACTACTTTTGGAATAATTGTTGCGATAATATCTACAAAACTCC ATATATCTACGG

TATTTTGTCTGATTTGATTTTCCAATGTATTTAATATTGCAATGATCTGAGCTAATA ATTCTTTAAGACC

GTTCATTCGATTATATAAATCATTTGTTTCAGATAATTTTGTCTGATAGAGTGCTTC CAAATTAGATATC

TCTGTTTCTAATAGAGTAATAATGCTCTTAAGAGTAGAGACTAGGTACTTCTGTGAA AATAACTCACCT

TCAATATCCTTTGTAGCTGATTGATCATTAACAATTAAATGACCAGTACGAGTATTT ACTAAAAGTTCT

GAATCTTTCGATTCCAGTTTAGTTTTTTCAGTTAATGGCTGAACGTACAATCTATAT GTCATAACTTATT

ATCACTTCCATATCATTTTTAAATTTAAGTTAGCAGTTGATATATTAATTATACCAA CTGCTAACTATAT

TAGAAACTTGTAATAATATTTACAAGCTTAGTATAGAATCCTTCATGTTTATCTTTG AATGCATTATATT

TAGTTGTTAATATCTTTTTATTAGCTTCGATTTCAACGCTTCGTAGATTGTAATAGT TTCTACCAAGATT

ATCAATTACTGTAGTATATAGATCGGCATAATCTAATAAATCATTTCTTAATTTAGT AATATTAGTACT

TAGATTCATTAGCTTATTATAGTTTGTTAAGAAAGACCCATCTACATTATTTGTAAT ACTTGTTATCTTA

TTACGAATATCAGTAATATCGGAAGTAGTTTTATCAACTTCAGCTTTTAATGCATCA ACCTGAGTTTTT

AAATTATTTATTCCACCAACAACTGCGTCTACAAAAGGTTTTAATAGATCATTATTA CTGTCAATTTCA

GATAAATTATCTCTTAACCAAGATAATTGATTTTTATATAGATTTGTTACTTTAAAT ATATCATATATAA

CTGTTGAGTTTAATGATAATAAGTTATTTAATTCTTTTGTAATTTCAATAATTTCAT AACTACCAGTATC

AGAATTTTTCGTATTAGATACAACGGATATATTTCCAGTATGTTCATCAATAATCAG TTCTCCAGGAAA

TCTAAATAGATCATTTTCTCGACTAAACGGAATTAATACATTTCGATCAAGATCTAC TGGAAGATTATA

ATTCTCAGTAACATTATTATCATGATCAATAATTCCGCTAGAGTAATTATTTACATC AATATAATAATA

AGAACTATTATACATATTATTTGACTGTTTTCTAGCGGTAATGATTAGTCGATATAT ACCATTTACACT

ACTGATATTCTTTAATAATGGGTCACCTATATTGATGATTGAATTATTAAGTGAAGC AGTATATACAAC

TCCCGGTTCTTTATTAATAATATCCAATACAAAAGTTGAATCAATATTAATAATTTT TCCATGACTAAT

ATTCTTAGCAATTGGTTTTGAAGGAGGTATGGTATCAATAGTGATAGTTTTAGATGA AGATGAACTTTT

ACCATTTAACTTACTAGTAGCTTTTACATTTAATGTAAATTTTCTAATAGATTTAAC GTAATTATAGTTC

GTAATAGGATCACCTAGAGTATACGGTAAACCATTTATTGTAATTTCATAGGTACAC ATTGGGATTCTT

ACAATATTAGGAATGATCAAACTATTTGTAAGGTTTCCTGAATTATCTGGAATATTA ATTACTGGTAAG

TCTGGTACTGTAACATTTAACATGTCTGACGTAATTTCTAAATTATTTTCAAGAATC ATATCATTATCCA

TTATTTTTCTAGCAGTGATGATGCAGGGTTCAGTAATTATAAATGGACCAGTATACT CTTTCCAAGAAT

TGTTAATAGAAGTCTTATACAGTTTACTTTTAATGTGTTCTCTTTCAGACTCAATAA ATACATATTCAAT

AGAAATATTATATGACTCGGAATAATATTTTTTATCATTATAATCTATTCTTGGTGG AGTATAAATATA

ATTCTTAACAATATTAAATTTAAATGTAGTATAACTTAACGTATAATTATGTCTATC TGTAAATACTGC

TAAGAATTCATGAGTCCCTCCCGAAGTGAATGTTGAACCAGAAGTATAATTGTTTCC ATCAATATAAC

AATTAAGCGTATAATTTGAATTATTATTCATTACAGTGATTGTTATATCATCAGCAC ACTGAGATATAT

CTGCAGAACTCACATCAAAAGGAGTTAATGGTTTAGATGATGATATTGATATTGACG GATTAACTGGA ACTGTAGTTTGATCCATTCCAGTAGTATTAATAGTCTGAGTTGCCATTAATTTATGTGAA GAATCAGAA

ACATTAGTGATATTACTTCCAGAAACTCCGCTAATCGTAACATCATCATGTAAATGG TTTCTCGTTGAT

GTAGCATATCTGTATAATTTAATAGTAGAATCAAAAAATATCGGCATATTATAGTTA GGCATAATAAA

TTTTTTCTTACCATTATAATCCATAACATACATACTATTATCTTTATCAATTTTACT ATCAGGCTTAAGA

ACAATATCATTAAATAATGGATTAGTATCACTAGATACTGAATCATGATATATAACA GTACTAATAAT

ATCTCCAACTTGTTCTGGTATAATAACTACGTTTACGGAAATCTGTACTACATCTGA ATCTACGCCATT

GCTAACATTAATATCTAGATTATAATCTCCTTCATCTTTAAATGATAATTTTAGTTT TGGATCATTCGTA

TTAGTGTCTAATGGTGTAGCGGTATATGTTTTTGAAGGATCATCAGTATCTGTAACA CTATAGGTATAC

GATGAATCTTTTTCAATATGAATTATAATATCAATTGATCCATCCCCATTAGTAATA CTATCTACTATA

GGTAAGATTAATGTTGCATTATCATCAGCAATAACTGAGAAAATTAAATCTTCAGGG GGATTAATCGT

ATTTATAAAATTAACAATCATTAATTCGTCTGAATTGAATAGTTTATTTATATCGAT TTTTCGATAAATA

TTAATCTCAGTATCAGTCTCATATAGCCCTAGATATGTGAGCATTGTATCTGAAACG TAATCGTTAACC

TCTATAACGTCACCATCATCATTAGTTACCGTTATATTAGTAGATTCCTGTAAGTCA TTTACTAATTCAT

TCACATATACTTTAAACGTATACTGATCGGTACCTTTAGTTAGTTTAATATATACGT CATTATCTTCTGC

AATTGTTATTGAAGTTGGTAATGATATACTAAACATGTTATAATTATTTGAGTCTAT TGTAATGTCATT

ATCAGTACCATTAATATTTAGTTTACCATTATAAATTCCAGTACCTTCAACGTGATA TACTCCAGTAAT

ATTAGAATCGCCAATATTAAATGTATCAATAGATAATTGTATATTTTCACTTCTAAC TACTAGTACTTT

CTGATTATCTGCAACTAATATACCCTTTGAGTTGTATATCTTAAATGATATCTCATC CGTATCTGAAGA

TATTCCTGTACTAGATGTTATTTTCATCATTTTATCATTTTTCGTATTACTAAATTT AGTAACAGTTGAT

GTAGTTTCAACACCATTAATATACATAATAATATTATCTAATTCACCCTTATACTTA GCAATAATCTCA

GTTGGATTATTTCCATTAAAGAAGAAAGGATAAAAGTCTACTGCAGTATAATCAATA TTTATTGCAAC

CTTATCATTAAATGTATCTACACTGTCTGGATCATCTGAGTCTTTTGGTATAGAGGG TTCATATGTGTC

ACTATATTTTACAATAGGATCTATAAAGTTGGTATATAATCCTGCAATTGAATCATT CTTGACAATAGG

TATATTTTCATTTCTGATTGATGTGTATGTTGATGGAATATCTACTCTATAAACATC AATATTAGTACCA

TACGCAGAAGTATGTCTAATCGAGTCTGAATTGTAAAGATATTTATTAATATTCGAT TTATCGATATAT

CCACTGAAAACATATATATCTGAAAATTCATCCATATTGAGAGTATATTCCGTTACC GTATCACTAATA

AAATCTTCATCTTCTGATATTGATTGAAATGATTCAATTAAGCTTTCTTGAAGATCA TTAATAAAATCT

TCGTTAGATAGATCATCGTCATCGCCAATAGTTGAAGCACTTAACATAGTGATATTA TTCTTACCAATA

GAACCTTTTACAACTGAACCATTACCTCCGCCAATAATCTGCGATATATTATTATTT ACATTAAATGAT

AAATTACTTACATCTTTTGGTAATCTAATTGCTTTATATAGGAAATTATCATTTATT CCTTGAGTTAGTA

TAAATAGTTGATATAATATACTAGAATCATCAGAATAATCAGAAGTTCCTCCAAAAT CATTTTCAATA

ATAACCCTAAATTTCAGTTGAGTTAATCCATTATACGCATTTGTACTATTATTAAAA TCTTCGTCTCCAG

TAATAAATCTTACTCTACTACCGTTACCGCCTGTGGGTGCTGTACTTTGTAATGTAA AGACTTTATTGG

TAGTACTCCAATTACTCCATTGATCCGATCTTTCATCTTTAACCGAATATTCTAGAT ATACTTTGTTAGC

CCCAAATGATGGAATTGAACTTATAAAATCTTTATAATACTTTCCATAATTACTAAA GTATGTTATATC

TGCAGGTCTAGAATATAATGGATTAATACCGTTATCAATAAAGAAAGGATTTACATT ATCTATCTTAAT

TGGATTTGGTTTAATCCCTTTCATATCATAATTCATTTTAAAATAAAATTTACGTGG ATCAACTAATGA TTTATTAGTTAAATCGTTAAACGCTTCTATTGTTAATTCAAATACTTTATTATGATAATT ATTATATACT

GCGTTTGGATTATCGCTTGCCAATGACAAAGTATATCCTGACGTATTCTCTTTATAA AACTTCTTAAGA

TCTGGATTATTAAGTGCTTTTATATTATATCGATAAATTACTGGTCGACCAGTTGAA TCATTTACCCCTG

AAAAACTAAAGGTATAATTAAGCTTATTTGCTTCACTAGTGTTTGCAGGAATCACTG TAGGATTATTTG

GATCATTACTCATAAATGTTAAAAATGATCGATCTTCATTTAACATACTAGCAGTAG TAACTATCCCCG

GTGCGCTCTTACTAATATTTATTACGTTTGGCATATTAGAAAGATTATTAAACACTT CAGTATTATCCG

GATCAATATTATCACTATATGATAGTACTGTATTAATTTTAGTTTCATCTGAAAAAT AAAATGGATCAA

TATCAAGATAATATAAATCTCCAACTTTAGTATCATAGTTATCTTTAGATAATCTAA ATTCGTGTAAAC

TACTCTGCGTTGTTACTTGGAAAATAATATCGACAAAAGCAGAATCTTCCGTACCAT TAATATTTTTAT

TTTCTAATTTTCCAAAAATAGAGAAACCGTTCTGATCTCCAACTATAGACTCATTTC CTTCCGTACCGG

ACTCAACTTCTATATTTGTGTATGTTAATGCTTCTCCATATGGATTCTCTACAAAGA ATGTTCTAGCAAT

TCCATAATCTGCAGGAGTCCAACTTTGTATGAATTGTATTAATTGTTCTCTAGTATG TGCTATTACTGTC

AAGAAATTTCACCACCTATATTTATAACTTCTTATAATTAATAGTTTAAAAATCCAT ACTAAGAAATAT

TTAATTCCTTAGTATGGACGATATTTTTATATTATCGGATCAATAATATCCGCTTCA GGATCATAGATTT

TTTGAGGATTCATATCCAAAATAATATTCTGACTAATATATTTGTTATTTATTTCTT CAGAATCTAATGA

AATATCCCAACTTAATAGATCATTATTATTACAATTAATAATAGTTTTTCCACGTTG ACGCATATAGTC

CATTAGAATTAATTTCCGGATACTACCTCTAGAATTATCATTTGTTATTCCAGTCAA TATATCAAAATT

ACTAGTTTGTCTTACGTTATAGTATGAATGATAGTAATTATCGTTTAAATTCATTTT ATCATACTTATAC

CAATCTAATATTAATTTAAGTTGAGTATGATCATCGTAGCTAAATCTAATCATTACA TTTATTAATGGA

TCAGCATAATCAATAATTTGAATACTTTTACCATTAAGTATTTTTACTTTACTAGAA TCTATTCTTAAAT

TATTAACGTAAACTGTAAATGTGCCTTTAATAAATATTACTGAATCGTCATCTAAAC TGAATACATCTG

TTGTTCCTTCAGCCGGCTTACTAAAAGTTCTTATATAGTTGGAGTTTTCATTAAGAA GATTTATTTCGAT

AGTAGATGTTTTAGGTACAATGCTTTTAAAAACAATTAATGACGGAATAGATTCAAA GTCAGGATCAA

TAATGGTATAATCAATTCCAGGATATAATGTTAATCCATCGATATTAATATCGATAT CTTCAGGATTAC

TATTAATGTTTGTAAAAATATTTGAATCATCATCTAACGTAGCAAATGGTAAACAAT CAATATCATATT

CATTTAAGTCTAATTGATTGTAGTATAACGAGCCACTATTTGTACCACTAGTCAAAA GATGTATTTCGG

TACCTTCATCCATATAAGATGAACCATATACGATAAGTCTTACTGTATTATATTCAG GTTCAATCTTAA

TATAATAATTGTATGGGTTAATTCTTCTAAAGAAATTCCAAGTTTTCTTCTTAATAA AGACTCTTAATTG

TGAAGGAGTAATTCCCGTTGGTAATGCAACATCCGTTAATAGTATACCAGTAGTTCC TAACATATTAGT

TTGATCTTCAAACGTATTATCAATTATATGAGTCTTAATTGTTTTCTCGGATTCAAC AATCTTACGTTTA

TTACCAGAGACAATTACTTCATATTTATCCGGAAGACTAGAATTCCCATCTAAAACA TCATTAGCATCA

TTCACATCAATATATTCTTTAATAAATCTTGAAGGCATGTATGCATATATTTTTCCA TCTAAACTATCTT

GTTGCTTAATCGATTTACGGAAAATATGTTTACCATTAATAAATATATCAGATATTA ATGAATTTTGTT

TCTTTTCATATGAACCATATTCCGAAGTAAAATCAATATAACCATACTGAGATTCAT CATTAATAAAAT

TATTTATAAACGGATCTTTTGTAACTTTTATTTTAGAGTTATCCAACTTAGTTTCAA ATGAATTATGTCC

CATTGTCTCTATAAATAATGTTTTATTACCTTGTTCTAATTCATTAACTAATGATTT TTCAATCATCCGA

ATATCATTGTCTGTATTCTTATATAAGATATCAGTAACATTTCTTGGATCAATATCC ATTTGGAATGTTT TAGTCTCTATAAGTTGTTCTGAATTAGTATTAAATATACTAAAGGTTATATCTTTATTGG GGGTGAAAT

TAAGTTCATCAATCTGTAATCGATAGTACTTTTCTTCTAATTCTGGAAGATCGTCTG GTTTATAATATAC

ACGTTGATAATTATCATTACCAATGATATTAATTAAGTCGCTTGAAACATCATCATT ACTCTCAGAAGA

AGAGAATATCATATTTTTAATCTTTACAGTAAGCTTATAATAATCTTCGATTCTTTT AAAATTATTAATG

ATGATAGTCTTTCCATCAATAGTTATTGTCATTATATATTCGGATGATAATAAATAT CTTAGTCTAAAA

TAGATTGATCCGTTCAGATAGTATGCATTCTTATATAGAATTTTATATATAATGTCT TCTGGAGTGGCTT

GAATATTTTTATTAGAATATCTAACATCTAAATCTTCATTAAGAACAGTATATCTAA TCATATCATTTC

CTAAAGGTAGCATTAATTCTGATAATACTGTTTCTTTATCATCAAAAGGAATATACA TATTGGCACTTT

GGTTTGCTTCAGGAAATATCCTACTAATAGAGTTCGATCTATAGTTTAGAGAAACAT TATAGTTACTTT

TATCTACAATATCTAAACTATGCATTAAATTAACATGAACATTTAAGAAAAATTTAC TATTTGTACTAT

TATTAAAACTGCGTTTTTCTATCCATGTATAATCAATACTTAAATCAGGAAGATATT CTAATTTATAGA

ATGTGGTATCTCTACTAGAATTATTAACAATAACAAATAGATTGGTTGCTACAATAT TTTCTGGATAGT

TATCTAACTGAATATTTTCAATAATATTTCGCTTAGTATTAATTAATACTAATTGAT TCATACTATCCAT

AAGAATAATATAATTTTTAACCAGTACTACTTTATCAATATTATTTCTAACGTTTGC TAACCATGTTTTA

TTCGTCAAGTTATTATTAGCATACTTAAAACTATATATATTTCCACTATATGATGAT ACGTATAATGTA

GATTTATCACTATCATATATCATAAAATTATTTGTCGATAATATTTTATCATTATAA TCTGTCTGACTTA

ATGATACTTTTTCTACAATAGAGTTATCTACAGACTTAATAATATTAATATTAAAAC TATCTTTTAATTC

TAGTCCTATAAATATTGTAAAGTCGATATTATTCGATTCAGGAATGATTTCAAAACC AGAAATAAAAT

ATGAAGCGGTATACAACACTTTTGTTGTATTCGTTATAGTATTTACTAGTATAATAT GTTGATACGTGG

AGTAGTATATAAAATCATTAACAATCCTTAATTGATTTACTAATTCATACTCATATG GAGAAGTATTAG

TTATTTTATTTATAGTTCCTGAGATATTATACATTCCAGTAGTTGTATTTCTACTAA AAGATACATAACT

GATACCATTCTTATGAAACATATATATCTTATTATCGATAACTGTAAAATCGATTAC TTCCTCATTAAT

ATCAAATGAACCTACTTTTTCTCCAGTACCAAAGTCTTTTATAATATCAATTCGATT CTTAATAGAACC

GGTAGGATATTTATATAATCTGAATAGTTCTTCTAAATATATACACATTGCAGGCAT ATATCCTGAATT

AGCATATGATATAGAATGAAATAAGTCTAACCTATTACGTTTTTGATATTTATCTAA TATATTCCCATT

CAATGTTATAGTCAATACTTTCACCATCTTTCTTTTACAATTATAAGGAATCGAGAA TAAAATATCCCG

ATTCCCAATTTATTTAAATAAGACTTGAAAAACTTGTAAATGTTTTTAGAGAGAATT TACCTAATGTAT

TTTCGATAATTGCTTCTCGATTAAGGTTAGCGCTTATAGATGATGACATTACCATAT GCATAAATGCAG

GAAGGTAATCAATAGCTAATACAGTAGAGTCTCCATACATTCTTACATAATTCTCTA AATAAGAGCGT

ACTTGTAATTTCTCTAAACCTTTTATTTTCTTGAGGTTATCAAAAAGTGTAAAGATG TCTTTATATAGTT

CCTTCTCGCTTAGATTAAATCCTTCTTCCATTTCTTTAATTAAAGATAATGAAGAAC CATTAAAGCAAG

CTTTATAGGCAATATCGTCTATTGTATTATTATAATTCTTTTTAGCCATTGCTAATA GATAAAACTTTGA

TAGAATAAAGGATACAAAGTCTGATTTAAAATCATTTAGGTTTAATGAAAACATTTT ATCAAATATCTT

TGAACCTAGTCTAGAATATGCAATAGATGAATTTTTCATTAATTCAGTATTACTTGT AAATCGATTCCA

ATTTCCATTTAATTCATAAGTAATCATTGCTTGTTGCATTAGTCCGAATAATGTTTT TGGTTGGATTTCT

CCACCTGCATTAGTGTATCGTGAAACATCAACTAATACGTCACGTTGATTGTTATAT CTTCTTTCAAAT

ACAATCAAGTATGATGGAAATTTATTTGATTTATTTGATATAGGAATGATTTTTCCA GAGTTATATAAC CCAACAACTTTATTTTTAGTAGGATAATTAATTCGTCTATTAATAATATTTATATTTTGA TCTAATACAT

CTTTAGATAAAACATCTTTACTAGTGTTTATTTTATTAAGTTTTATTTTAAGATCAT GCTGAAAATTAGA

TGTATTGAAAATGGCGGAATCACTTAATTGTACCATTATTTCACTTTCCCTTCAATT AATTTATATGATA

TTAATTTGTTCAATATATTAACATTTTTTACATTTATATATTATAAATTCGTATAAT GGAAATATAATAA

AATTTTCAGTTTATCGGTTAAAATATTATTATATTATAAAATAAATGTGATAAGGAT GGATTATATTAT

GAGTGATAAAAAAATGCTTAAAGTAGGATTTCTTAGCCCAAATGATGATAGGATTCG TTTTAAAGAAG

TAGATTTTTCGAATAGTGAATCTTATGATAAAGAAATTGTGAGTGTTATTAGTCCTA CCGGAAATATTG

ATGCAGGAATCATGAATCTTAATGAAGATTTAGAAATTCGTAACTTCTTAATTTTAT TTGATAATGAAA

TGTCAACAAATAAAGGAGAATATAATTTTACACATTCAATTAGTCCTCTTTTTGGTG AAGTTGCTTTTG

TAAAATTCGGTTATACTGGGGATAATATGGAACCAGTAAGCATGTTAGATGATGAAG CTGAGGTTCTC

AGTGATATTATTTATCAAGAAAAAACTTCTGATCGAGCAATTGAATTTAAAGAAAAA ATTCTTGAAGA

AGTAAGAATTTACGGTAAAGATGGATTTTTACGTAAATATAATGAAAGTATTGAAGA GGCGCAAAAA

ATGTATGAAGATAATTTTTCAGAAGAAGAAGAAAAATAATTAAGAATGGATGGTGGA TTATAATTGTC

TAATATAAACGTAGTTAGTATTGCAGATTTACATTTTGGTAAGAAAGATGATAGTCG ACTAATGAATG

AATTAACAACAATATTTATTCCACAGATTAAGAATATTCATGAATCTGATAAAATTG ATTTGATTGTTA

TTGCTGGAGATCTATTTGACCGTATTCTTAAGTTTGATGAAGTTGGTGGAAAATTAG TATTGAATTTTA

TGCAAGAACTTATTGAATGGACAAATAAAAATAATATTTATTTTCGAATTATTCAGG GAACTAAAACT

CATGACTATAATCAATTAGCTGTGTTTAGAAAAGCAGAAGTTGATAATTATAATTTT AAAATTTATGAA

ACGGTATATAATGAAAAATTGACTATCAATGAAAAAGAATTTAATATTTTATATTTA CCTGAAGAATA

TCCTGAAGATATGAATGATTATTATAAAGAATTCTTTGATGTTCAAGAAAATACGTA TGATATGATTTT

CGGTCATGGAATGATCGATTTTGTAGCTTTCACTGGTTATGAAGATGATACTGAAAA AATTGTAAAGA

AAGCACCAGTATTTGTTGCGGATGACTTAATTAAAATTACAAAAGGACCAATATGTT TTGGACATATT

CACGACTATCATGAATATAAAAAACAAATATATTATTCAGGTTCATTCTCCAGATAT TCTCATGGCGAT

ACTATGGATAAAGGATATTTATATATTAAGTTAAACAGTGAAGATACTTCTGAATAT GAAATTAGTTTC

TATGTTAATGAATTAGCTCCAACATATGCCACTATTGATTTAGATAAAATCAAATAT GATAATATGGA

AGATTTAGCATCATTAATTAATGATATTCGTGAAGAATATGACTTCATTCGAATTAA ATCAACAAATA

ATAATGATAGTTCTATTGTAAGAAAAGTTATTGAAAATAGTCCTAATATTAAAGTTA CTTTAAAGAAT

AAGAATAACGAAGAACAACAAGTTGATTCTAAATGGAACTTCATTCTTGATAGAGAG CTTGATACTGA

CGACTCTATAAAGAAATTTATTAAAATTAAATATGATAAAGATATCGATATTAGTAA GATTAAAGCAA

TTCTTAATCCAGAGATTGAAGATATTGATGATATTATTAAGAATATTTATGATAAGA AAAAATAATTA

ATAATCTTTATTAAGAAGTGAATTATGAAAGGAATGTTTCATTGTGCCATTTATGGA TAATAGCGAAC

GTACAAGAGTCTTTAGATCTAGAATGGATGAATCTTCTCAACAAGAATTTCCATTAA AGATTTCCGTAT

CATACTTATTTAGTTTAGCAAGATATGTGGTATATCCAAGTAAACTTATCACTAGAA CTAATTTACGGA

ATTTAGATACATTATTATCAGCAGTCGATATTGATAGATCTTATTTAGAAAATGAAG TAATGGAAAAG

AATGCATTTATATTCTTAAGAGAAATTAACCGTGTATTATTACATCAACAATCAACA ATAGAAACATT

GTTTGATTATATTGATGATGAATTAAAAGATAGAGAAATCTCTGAAGATGCTCTTCA AGAATGTGTAA

ACAATATTGCAATGGTGTTTGATGATAATTTCATTCTTGATGATAGTGAAATATTAA GCTTAACAAACT ATGTAGAATCCAGATTAAAGATTATGGCACTATATCGTCAACGTGATAGAATGGAAGGTA TTTTAGAA

TTAATCAAAATGAATAAATCTCCAAACGAAATTAATACTGAATTTAAAGATTTTGTT ACGCAGAATGC

ATTACAATTAAGAAAGATTGAAACGAATAATCGAAGTTCAATGGACGATATTATGTT TAGCAGAGATA

ATGATCGATCAGTAGATTCACTAGACTCTACTATTAGACAATTAAGAAGTCCTAGTA ATAAATTATTA

ACAGGATATAGTAAGTTTAATGAAATGATTAATGGTGGTTTAGAGGATGGTCGACTT TATTTACTCTTC

GGCGTTCCTAAATCATTTAAGTCTGGTGTTATGTTAAATATTGGAATGTCAGTATGT CATAATAACGCA

GGATTTAAGACAAAAGATCCTAATAAAGAACCAACCGTTGTTTATTTATCTCAAGAA AATACAATTAT

AGAAACAGTAGAACGATTATATGAATATATTACTGGTACTAGTATTAATGAATCACA AGCTACTACGC

AAGATGTTTTAGAATTAATCATGCAATATACGTATGATTGTACTGGTATTTATTTAA AAATTATGTATA

GACCAAATAAAAGTATTGATACAAGTTATCTATATAATATTTATGATGAGCTTAATG AAGAAGGTAAA

GAATGCATCTTTATGATTCAAGATTATACTCGAAGAATTAGACCTTCTGAAGGGCAA AATCAAGATAT

TCGGATACAACTCGGTAATATATCTGATGAGTTCTGTACGTTTGCTAAGGAAAAAGG TATCCCTGTAAT

GTCGGCGGGACAATTAAACCGTAATGCAAATGAAATTGTAGAGGATGCTCTTGTTAA GAATCGTTCAG

ACTTTATTAATAAGTTAGGTCGCCATCATATTGCAGAGTCTGCAATGTTACTTGAAA ATGCTGATTATG

GAATTATCATTGGTCGACAAGATTATCTTCCAGAGGGTGAAGACGAAATTAATCGCA AAAGTTATATG

TCATTTAAACTTATTGCTTCTCGTGGGAAAAATAAGGATAAAGATAGCAATATGTTC TCTCAACCTTTT

GAAAATGGATTTAAAATTGCAGAAGATATTAATCTAGCTGAACCATTAGCAAAATTA AGAATTAATGA

ACAACAGTCTCAACAAGATATGGAAAATAGTGCTGACGAAGTAATTACTTCAAGAAC TCCTAGATATA

ACAGTACTAGTAAATCTAGTAGTATAGTTCCGGGAATCAATACTGGTAAGAGACGAA CAAATCTTTCA

TCAACAGCATTATTACAAGAAGATGATATTCCGTTCTAAATAATATTAATAACCTAA CATCCTTTTTTA

TAGGGATGTTAGGTTAATTTTTTTTTTTTAGATAGATTCGGCTTTTTGACGTAATTT ACTAAAATCGATA

TTAAACATTTTAAGTGTATTCATACTTTCTAGTATAGTATAAGATATAATAGATTCT ACAATTGTCATTT

CTGCAATATCTTCTTTTTTAGATTCTGATAGATCCATATTTTCCATTACGTATGATA AGCGTTCTTCACT

AATTTTCATATATAATGATTTTTCATCTTTAACTTCTACATTATTTTCATTGCATTT ATCAACAAAGTTTT

TGTATTTCTTCTCATAATCAATTACATTGATAACTTTATCTTCAATTACGTTTACTG CAGATTCAATTAA

TGATTTCTCCTCATCATGGATAGAAGATACAATATCTCCAACTTGGTCAAATGATAA TTTCTCTTCATTT

ACATAATGACTGACTTTTGTCTTAACAAGACTTAATAAGTCACCAAAGGCACCATGC TCTTGAATATTG

ATTGATTTATTTTCTACAATAGTATTAAAAGCATTAATACATTCATTATAAATATAA TCAACATTCCCTT

_{GTTTTTGAACTTCATCAATAGGAATAGCTCGGTATACAATACTTCCAAATAATGT TGGAGCTACTTCTT}

CAGCATGTTCATTAATTCGATTTTCCTTTTGAACCATCTTTTCACGTTCTTCAGCTT CACGCTGAACCGT

AATAGACGTTGTTCGTAGTAATTTACTCTTGTTTTCCATATCTAAATTTTCTTGTAA TGCTTTTTCTTCTT

CTTTCTTTTTACGGAAATATTCAGTACGTGCATTATTTTCTTCTCTAAGATTTCTTG AACTTTCACCAAA

GATACTAAGTCTTGACATTAATTTTCACTCTCCTATAATTTTTGCTATATTAATTTG TTTGATAAGTTAT

ATTAGCTACATGCTCATATTTTTTACCTAGATTGATAGTAGTGACTTTACCATTACT ATCTGTCGTTTCT

ACAATATTATCAGAAAGTGTTTTCTTAATATTGATATATTCAGGAACATATTCAATG ATTTCTTGTTTTG

AGAGATCATTAATATTTCTTGCATTGTTAAGGATTTTTTGATATTTATTAGATATCT TTTCATCATAATT

ACCACTTAAACCGTTATATTCAATATAGCTAATGATCGCAAATTCTTCTTCTAACAA TCTTAATAGATT AGATATAGGTACGATTCCATCAGTATTACAGGCTTCAATAAAGTCGGAAATAAATTTCTT AATTGATA

AGTCATCATTATCATTAACGGCTTCATATGTGTGAATAGTTAAATCAATTAGCATGT CAATGCGAGTAA

TAAGATCATACTTAACACTATCTCCATCCACTTCAGTATTTAAGTAATAATATTTAG ATGGTCCCCAAC

TATTATAAAATTTCATATCAATTGTAGTATTATTTTCCAGTTTAGGAATAACATTGC TTAATATAGTGAT

ATACGATTCAATTAATGTATATAAATAACTATATTCATATATAAAATATTGTAAACT AATGAGCGGTAT

CATTTCAACTTTAAAATCCTTATTTGCGTCACTAACGTTTGAAGCACCTACTCTAGT TACTGTACTTGTC

ATAATACTAGAAAGATTACGATATAACTTTACGGTAGAATTAGTAGTTACTGATAAT GCCAATACATA

ATTATCAATATTTCTATTAGCATCTGGAAACTCATCATCAAACAATTCAATTTCATT ATTATTCTTTGTA

CCAACAGTCTTATATGAATTATCTTTATAAAGAATTCCGATCTTAATATATAGATCT TCATCAATAAAT

ACATTATCTAGAACATCACCATTTTCATCATATAGCGAGTTTGATAATGATAATAAT CCTTTATTAAAT

TTACGATTAGTTGATAATTTTGCAGTATAAGTAGACTCTGCTTGTTCTGGATTTTCA CGTTCAAATTCAA

AGTAACCATACTTCTTATTAGAGTTTTTTGACATTAAGATACCTCGTACGCAAATAC GTTTATCTAAGT

CGCCTATCGTTTCATTACTGTTTAGATCAAACTTAATAGTATACGTATCGGAATCCA AAGTAGATTCAA

AATCATGAATTTTTGTTATATTAAGTTTATTGATAATCATTGTTGTAGGAATTAAGT TATTAAGATAAC

TGTATGATGTATCGAATGTTTCATCAATATCCAGTTTATAATATTTAGCACTTAATA CAGGATCAATAT

CTATTTTAACTAAGAATGGATTAGTATATACAAGCGTATTTTTATCATTAATAGATT TTTTAATATCATC

AGTATATCCATCGGGAAGATGTTTATATTTTTTATCAATATAATCATACTGAATTAA TGAATGTTCCGG

AATTACATATCCATTAATATCGTCACCTAACAGTTGATCTGTAAAATATTTCTTAGA GAAAGTTACACT

ACTTGCAGTATTTGTAGGAATAACCTTTTTATCATTATCACGTAATAATAAAAATGC ATTATATAAACG

CTGAAGAACATCATTTCGCTTTTTCATAAAGTTTATTGATGAGTCATTTAAGCTTGA TGCTCGATCAAT

ATTTCGGAAATAGATATCTAAGTCAGTATCCATAATTAAATTATCTCTACCGAGAGC AGTTTCAATAAT

TTTGTCTTTCATACCGCTAGTACTTAGTTTATCATTACCTCCTGAAGCAGAGGTAAT AGGAACTACTGT

TGTGAGCATCTTTGAAAAGTTATTACTTGCTGAATTAGTAAAGTTAAATAATACTTC TCCATCAAAAGT

AAAGTTTCCTTCAGAACCTTTTGTAGTTAATATCTCAATGGTTATCTTACTATTATA TCTAGGTCTAAAG

TTATTAACTAATGAAGAAAAAGATATCTGTAATTTATTATCATCAACAAACGTATAA TAACAGAATTT

CTCATCAGGATTAGAAGGATTAAAGGTATTATTAAAGTATGCGTTTAATTTTACTTT TTCGCCCATATA

CGTATAATATATATTGAATCCTGCCAATTGATCGTCAAACTCTGCAGTATAGAATAA ATTATCACTAAT

ATCTTCAGACAATATATCAAAGTCAAAAGAACTACTTTGAACTTGGTAAATATCTAA ATTTAGATACA

TATACTTTTCACCATCAAAGATAGATTGATAAACTTTTATCTCAGGAGTACTAAGTT CAATATATGGGA

ATGTACTTACTTCATCAATAAGATATCTAGCTGTAATCGTATAATCATTATTCTGAT TTTGTTTCATTAA

TATTTGTACGTCATAAGGTAACTGGAATTTAAATTTACCCACAGAAAATTCAAATTC TCGATCTAATAT

GATCTGATAAGTTTTAAGAGCTTTAACTTCGATATATTGATCTTCGATAATTTCTTC CCTTAATGGAGA

ATTTATTAAATCCTCTTTACGTATAACCATATTAACTAACATATGAGAAGGGTTTGA TAGTACTAATGG

TACGTTATATAATTTTGCATAATTGAAGATACTATCTGGGAATGATGCACTATTTAA GAAGTGTTCATC

ATACAGTACATTACGATGATATACCGAGTTTTTAACCTCATGGGCTGCAATTTCATT AAAGTATCCAAA

GAAACCAGTTTTTAATAAGTTTAATGCAGCATTATTTCCTTCAGAACCAGTAGCAAT ATTTGTATCATC

AATATTAAAATATGTGCTTGCCATTTTAAGCCAATGTTCATGTACGTCATATGACGT TTGATTTACTTTA ACTACTGAACTTGTATCTTCTTTAGCATTCTTCATAAAAGAAGGTACATCTGTTATATCG TTTGGATTAT

TTTTATTTGCCATTTATTCTCACGCCCAATCACTATTTAATTATCCAATACAAATTT GAGTTTATATTTTT

TCTTTTCATTATCACCATAGTTTTCAAGAACTACTGCAGGTCTATCTAATTTTGTTA GGTCTAAGTCTGT

AAAAAAGTCATTATATTTCTTAGCAGATCCCGGAGAAGTACTATATATAATACTTTC TGAATCTTTACT

AGACGCTAATACTGGAGAGTCTAATGATACTGAATTAAAGTCCATTAATATTGCGGG ATCCATATCTT

CTTTATATGAATACGCATAGTTAAAACTTAACTGAGCGATATCTTTTGAACCTCCAA TATCACTATTCA

TTACGTCATATGGAACATTTGTTGGTGAACATCCAGTGTATTTAGTATAGTATAATA TCGTTTCCATAT

CAAAATCTAATAAAAAGTAATATATGGAACTTGTATAATCAATATATCGATTCATAA ATACTTGTGGA

TTAGGTTTCATTTGTCCTCTAGATACTGCTTCAATATAGTCAGTCCATAATTTATGA ATCTGTAGTATTG

TACTATTTTTATCTTCTTCAAAAGTTACGCTAGTTTCATCAGCTACTACACTATTAA TAAATGGTCCAGG

AAGTAATTGCTTGTGACCATAAAACGTTTCATTAACTTCTTTAGTAATAGTAGATAT TCCTTTAAGTGA

CATGTTAATAAATCTATTAGTTAACGGTTTTATGAAAGAACTATTTGAACCATATAT AGATCCTCCGCC

AGTCTTACTGGTTGCGTTCCCACCATAATTAAGCATATTTAATATTTCAGGGCGATT ATCCCTCATATA

TTGAAAAAAAGAATTCACATTTATATTTTCATCCGTTAAGTTAAGTTTTGGAGTAGT AACAAATACCAT

AGGGAATGCTTTAACCATCGGTTCATTTCTTAAGCTATTTTCCAATCTATATGGATT AAAATATTTATTC

TCATTTATATTATAATTCCCTATAATCTTTTTTCTAATTTCGTCTGACTTTGACAAA AGTTTTCACCAAC

TTTCATATTAAGATCCTAGTATGTTATAAATTATTGTTAATGTATGCATGAAAATAT TAATTTATATTTT

ATTTATATATTATAAATTCGTAATAGATATAGTGATCATCCTTATAGAGTAAGTTTA ATAATTAATATT

AAGAAAAATGATTTATATTACTGTCCATATTAAATAAAATATGACCTCACACCAGTA ATATAAATTCT

GTAAAATTATTTGGCTTAACTCTATCAGCGCTATATAAATTGAAATCATGCATATCG GAGAATATTAAA

TAATTCTTAGGGTTAGTCGATACAGTGAGAAACTATATCTATTAAAAAATATTATTG TCTTACATGGGG

GCGTTCTTATGTGCTATATGATTGAATAAAAAGAAAAAATATGATTTAGAAAAAACA GTAATAATACT

TCTTAGTATTATTAATAAGATCCTATACTGAATAAAATTGAGGTATATGAAAGCGCT CATAGGATTATT

TATTAAAGATTATTAGAGTCACATTTCATTAATTGATCTGTGACTCTAATAATCTTT ATTTAATTTTTTT

TTTTTATAACGCTTCCTATGATAAAACAATAAAATATAAAGTAATATTAATTAGGTC ATCTAAATTGAA

AAGGAGAGAGCGTAAATGTCAAAAAGCGTATTGCTAAATTTGACTTCACTCTTTGGT GAAGTAGTTCT

TAGTAAAAAAGGACAATCTGAATTAGATAAAAGTTATAAAGAATTAGTTAAAAATAA ATCTGCTCGTA

ATAGTTATCTAAATACAATTAAAGGAAAAGCAGAATCTGCTATTATGCAATTTCCTT TAGTAATTTCTA

ATAATATATCTATCGGAGTTTTAGATGGTATTCGTAGAAATATTGAAATTGAACGTG CTACGGAGTTCG

GATTAGTATTGTCTAACGAACCAGTACAAAATGTTACAACTAATGCGGAATTCATGA ATAAATATCAC

ACTAACTTTAGTCTTGGAGAAGATATTTCTTCAGCACATAATGAATTCAATCAAGAG TCTAAATATATG

GAAGAAAAATTAGAAATGCGTTCACTTAATGATTTTACAAGATCTCGTCAATATCTT AGAGAAGAAGG

CGAACAAGATTTTGTTAATGCTAAGATTGATAAGGATAAAGAAGAAATGAGTAGAGT TGAAAGAAGA

ATTCAGAATTCTCGTATAGTTTCTGATCGAAATGCAATCTCTCCATTAATTGTAAAC AGTCCTATTACTT

ATAGTATTTCTAAAGTCTTTAATAATGATGGAAAAGAAATTAAGGTTGATCCTCCAA AAATTATTGAA

GGTCAAATTCGTTTTGGAATTAAAGCGGTATCTCATTTAGTTAATAGCGAAGATATT GTATTTTATCTT

GGCGATGCCGCTAGACGTAGTAATTTCTTAGCAAAAGTAGTTCGGTTTACTTCTGGC GAGCTTAAGTTT GGTAAGGATTTAATTCTAGCAAGCGAACGTAATAAACGTTTAGTACATGACCGTAAAGGT TCTGGTGC

TATTTGGAGAAACATGAATTATATTTCTGAACTGAATAATATTCGTGCCAATGTAGG CAATGTAAATA

AAATGCAAGTACCTACTATTACTTTAGCAATTAGTAAAGAAGAAGTAGATTCTATTG CAGAAAAGACA

GGAATCAATTTTATCGATAATCCTAACGCTACAGAACGTTTGTTTAAAGAATTTTAC TTATTAGACTTC

ATGATCATTGATGAACTAAATGAAGTAGCATACAAATTTAATCGTACTGGAAAAACA TATGACCGTTT

TAGCCTACGTTCTTTAGAGATTTCAGGATCTACTGAAAGTCAGTTAAAGAAACCTAT GGAATTCAGTC

AATTAAATAAAATGATTAACTCTATGAGAAAATAAGAAAGGATAGGTGAATAATTCA ATGCGTGGATT

TAATAATCGTTTAAAAAATAAACCAACATCTTCTAAAGATGCCTTACAACAGTTATT AGTTGAGAGTG

GCGGATTAGAAATGAATAAATATAAATTACTTTCTGAAGAAGGTAAAATTGGTATTA GTGACCGAGTG

TTAATTACTCTTATGAAATCAATTAAACCAAAATTAGAAAAACCGGTATTTAAGGAT ATTACTAAGTCT

AAAGGTGATATTACTAAATATAAAGCTTATGATGATCTAGAAAAAGTATTAAATAAA GTTCGTTCCGT

TATTTCAAACAGTTCTAAACCTGTAGATAAAGACGTTAAAGAAAATATGTCAAGCTT AGATACTGTTT

ATGATTTTGTTATTCGTGAAAAAGATGCATTTATGCGTGGATTTAGTAATAAAGATT CTTTAGTAATGT

CATTATATGTATCTTGTGTTTCGGTTATTGCAGAAGGATCATTAGTAATGTTTACAG ATGCTTTAGAAC

CTACTTCCGATAACTTTGGAAATATTACAATTAATGTTAAAGATCGTCCGAAATCAA TGAATAAGAGT

TTATTTATTGGACTAAGACAATTTTCTGATATGGTTAATGCTAAAAAATTAAAAGAT ATTATTAAAGGT

GGACAAATTAACTTAGAAGAAGAACTAGGTGAAAGCTTTGTTGGATCTCTTTCAGTA TTGGGTAAATT

CTTTAATAAAGTAGCAGATAGTATGGATGATGCTAAAGAAAAAGCCCATGATGATGC AGATTCTCCAA

AAGGTGAAGATAGTGCAATGATTCGATTCTTCAAATCAAATAAATTTGATAAAGCAT CGGACGTTACT

CGTAAGATTGGTACTCGAGTAATTCTACCGATTGTTGCATTATTATTAGTATGTATG TTTATTCGCCTTG

TAGTATTTATTATTTATCGTACTCGTGTAAACGTTGCAGACAATCTTCGTAGTGCTG CTGAAGTTATTG

ATGAGAACTCTATTCGAATTCAAGATAAAAATGTACGTGAACGACAAGAAAAGTCTG CTAAACTATTC

CGTAAACTAGCGGATAAAGTAGATGTAGACTTTAATGTGGCAGACTCTGGTGCTGAT AAGGATATTCG

TCAACAAGATGAATTAATGGCTAAAGGTGCAGATGATATGATTAGTTCATATCAAAA TAATGCTAACG

AGTTTGGTATCTAAAAAAAAATATCCCTATACATTCTAAAATTGAATGTATAGGGAT ATATATTATGA

AATTTTACGTAATATAATTTGACCACCATTATCAGTAGTATTATTACTTTTAGTTGA AAATATTTCCGTC

ATTTTAAGAACCTGATAATCACCATTATATTTATTATAATATTCAGAATCAAACGTT ATAGTGAATTTT

TTAAAACAGTCATCGATATTTATATCCATATTATTAAAACTAAATCTTAGTATGGTA TTATTTTCAGTTA

TTCGTTTAGTATATTCCTGTAGATTTTTATTATCATATTTATTTTCATATACAATTG TTTTATTAATAGTA

CCATTTCTATCCTTAATACTATCTATTTGATAACTGTCTTTTTCTAAACCTATCATG TCACGATTAAAAA

TAATATTATTTGTACCATATAATTCTGCATACAACTCAGTCTGATCCATAATAACAA CACTATTAATCT

TAGTATTAATATACTTATCAGTTATTCCATTTAATTGATTAGTTTCACTATAAGTAC CCATGATATTCTG

GTCTTCAGGATTAGCATTAACTGGTATTTTAACGTCTATACGTATATTTCCGGACTC AACTATTTCCATA

GAAGACATTGGAGTAATTACTAATTTATTATATGACATAAACACTTTTAGACTATCA TTATATATTCCG

TAAGCATTATTAATGTGGCTAATATTAGTTAGAATATTTCCGGGTATTAAGGCTAAT TGATCGTATATT

TTTTGATTGTCTGGAGAAGATAGATATGTTCTTACTGGAAGAAGAGTTAATAATCTA GTAATGACTTCA

GTAACATTAGTATTTGAATATATACCGCTAGTATTATATTTATTAATAGATAGACAT ATTTCAGGGACG CATAAACATTCAAATTCTTCATACTGGTAATTTGTATCTGTTGTATCTTGGGTTAATCTA TCACTAATAT

TAATCGCCCTCTTATCAATAATAAGCGGCTTTAGAATAATATCTCCGAGAAATATAT CATTAATATATG

AGTTGGTAGTATCCGCATCAATGGATGAAGCTCCTAAACTTACTACAAATTTCTCAG AATCTTCTTGTA

AACTTACCATAACAGATACTGGTAATTTATAGACTAATGATATCAGTGGCATTTTAT AATTTTGAAAAT

CAATATCGATTTTAGTTAATCGAATATATTCAGAAGCATCAAACATATTTCCATCTG AGAATAAGAACT

TACTACGTAGATTAAAAGTTTTTTTAGTTATACGAGAATAATCCATTTATTATTTTT CACATCCATTTCA

TTCATTCAATATAGTAATATGTTTATTTATTAAAATAAATTTATAAGAATATATTAT AATAATAGATTA

TAATATATTTAGGGAGTTGTTTATATGGATTACGGAAATTATTTTGGCTATGATACA GAAAATATCGAA

AAGATTATGAACTCAAAGAAAGTTAAATATACAAAACTCATGTCAATGGTAAAGAAT TATGTAACGA

GGGAATCTATTGGCAAGAATGTAAATATCTATATTGATATGAATACTATTTTAAAGC AGATATATAAT

AAGGATAATATTGAAATCTTTAATCATTTAAAGAGTGATAAACGTTTATTTATTACT GCTGAAATTATA

AATATTATTGGTCACTATAGACATTTCTTTTCTTCAAGATTGAAAATGTATACTACG TTTTATTTATTTA

CTTCTTTTGAAAAATCATCATATCATACAAATATATATCCTGATTATCGTAAAGAAT ATTACGAAAAAA

GATTGGGTGATAGAGATTTTGTTTTTTCAAATATTAATAAGATTATTAAGGATAATA TGAATATCGTTA

AGAAGATTTTAAAGTATGTACCAAACGCATATTTGATTAATACAAAAGATAATGATC CTTCATTAGTA

CCTACTTATTTATTAAATGATAATCGTTTTACTTTAGATACCGACTTGAATATTATT ATTAGCAATGATA

AACTTTTCAGACAAGATTTATTATATAGGGATAATACGCTTATCTTAGAAATTAAAG GAAAAGATAAT

AAACGACTTATCGCTTATGAGGACGTTATCAATACTATTGTAGATAGTACTAAAGGT AAAAGGGTTTA

TTCAGACTATAACTTATTAACAGAATCCATTACACTTCTGGATCCTCTTGTAAAGAA TAAAGAATATAA

TATTAATTCAATTAAACGAACTAGTGAAATGAAAGCACTAGACATTATTGAAAAAGG TATTAATGATA

ATATTATTTCTTCACAAAGCTATTATGACGTAGATGAAGCATATAATGATTTAGCTT TTTATCTTGGTG

AAAATAATGAGGATGAATTTAAAAGAAATATGTCAATCGTTAATCATAAAATTGCAA TGTCACATACT

TTTAAAGATTTAGAACACGTTATACTTTCCCAAATAATTGATCTAGAGGATGATAGA GGATTAATGGA

ATTGAATGATAAGTTCTTTTCAAAATATCCTATTGTTATGGACTATCTTGGTGAAAG TTTCTATGATCC

GAGATAAAAAAAAAAATATCCCTAATGCTAATATTACTTAGCATTAGGGACTTATTA TATACTTATTTT

_{TTTTTTTTAGACTGATTTAATAAATTCAATAATTTCCATTGACATTAAAACTTTA TCCATATCTTCGATA}

AATACTTCATTATCATTTTCATCAATATACATAAAATCATAATTATATGAGGTTGAT AATGACATGATA

AAGTTTTCACGTTGAACTAGATCAATAATACTGTCATACTCAGTAAGAACTTCTCCA TAGCTTTCTGAT

GTTACGATCTTATTATTAATCTTATTACTAATGCGATTTCTTTTTCCAGAAGGAATA GTTTTACTTAGTA

GAACTTTGGGTAAAAGTTTATAGTTATTCTTTTCAAGTTCTCTAATCATCGCAACTA GTAATACTAGTA

CTCTGGGTTCACGGAAGTTCTTAATGGCAAATCTTTTTGCAAAGTACATATTCATAA GTGAAATTTGGA

ATTCGTTTAAATGTTTAACATTACTACTTAAACGTACAATTTCTTCATTAGTAATAT TATATTTTTCGAT

AGAGTCTCTCACATACTTATCGATAGATGCATCATTAATAACGCTTGACATTTCATT ATGTTTATGGTA

CTGAATTAAAGAAAATTTATCATTCTCATCTAGATCGTCATCTGAACTAGAAATCTT GATTACTTTGAA

TTGTAGTGCATAATTAGAACGGAAAGCATATTCAATCTTTCTTTTAATAACTACGTC TAAATACGATAT

TGATGATTTATTAATAGAAAGTTTGCATATAATTGTACGTATAATTTCATCGGTAAT TTTTTGGTTTAAT

ATGTCTTCATCTACAGATATATTTTGCAAGAAGTACCAGATAACTTTATCTTTGTAT AACGTCTTTTTAA TACGTGGTTCAACAATTTTGCTAATCTTAGTAAGAATATTAATCCCTTTTTGATTACTAA AATAGCGAT

TAATTAATTTAAAAGTCTTTAAGAATAGTTGTTCATTGTAAGGCTTATTTTTAGCAT TACCTGAAGTAA

TAAGATATTCACATATAGTAGGAATTAACAAACGTTGCATGATTGCAGAACGGATTA GTACTTTATTT

GATTCATCAGTTACTTGTAGTTCAGGAACAATTTTATCAGAGTTAGTTCTACTATAA TCATCTAATGAA

ATCGTATATGTAGAATCAACTACTGCATCAATAGCTTGTAATAACTTATCAAATTTA ATAAAATCTTCG

AAATCTTCAATAAATTTACTTTCAGTATAATCTTCATCCATAAACATGTTTACTTTA AAATTTAATAGTT

TATAGGCAATTTCAGGAACTTCATTTAAAAAGTAGTTTAAATCATTGTAAATAATAT GATAGATATTTG

AATAAATTGCTTGATGAATATTATATTCAAATAACTTTTCTTTACCCTCTAAATTAG CATTCTCTAAAAT

AGAAGCAAAGTCTACAACCATCTTTTTGGGATGAGCATAGTTATCTTCTGTAATATA AGTTGTAATGTC

TTTACGATGTTCAACTTTTTCAATAGTTACCATTTCGTTTGGATCATTCTCACTTTT AGGTAAAGATACA

GTTACTTCTTTTAATCCTTCAATAGATATATACTTATTTTTTAACTTAAACTCTTCC TTCACACTATTACC

CCTAACTTTTGTGTTATCAGACGTTATTGTCACTCAAAAACACCAACCATTCTCTTT TTATTTTTATTAA

TAATATAATTGGGATGAGATTAATTTTTCATCATATACATATCAACCTTTCTTATTT ATATATACTATAC

CACACTTATATATAATATATAATTGAAAAGTTATTAACGTTTATTAATAGATGTTCT ACGAGATTTAGA

_{TTTTTTATTACGATCAAAGATACTTTGTTTCTTAGGTTTATCGATATTTTTATTT TTAGGTTTTCCTTTAC}

TTCTAATATCTTTTATCTTCTTGTTATGAAGTCTTCTATTCTTATAACGCTCAATTT CAACAAGCTTTCTT

TCTGAAGCGGGTATATTTCTAGATACTTGTATTTTGTCAATAGGTTTTAATCTTTCT AATGAGGGAAAT

GTTAATAGATTATTCTTTTCTAGATATATAAGGGCAAAATAAACACTTTTTTCAAAT CCATAAATTTGG

TTTGGGTTTCTTACTTTAGGTTCATCTACTAAAGATTTAATACTCATTTTATTCTTA AGCCAATCAATAA

TCAAACCATCTCGATTATAAATATATCCATACGTAAACATAAAGTTAGGATTATTAC TATAGAAACTG

ATATGCGAGTTTAGAATAGAAACGTTTGTATTATTTTTGTCTATTTTAATTACTACG TCATAAACCATTT

TTTCTTCAATATACGTTTCAGAAGGAATTTTAAATACATAGTACAAACTATCTTCAT CTTTAAATACTTC

TACACTAAACAATCTTTTAGCTTTTTTATACAGAGTATTAAATCGGTCATACATATT GGCGATAATCAT

ATCCCGCCTAGCTAATCCTGCAGAACCTTTTCCTGAAGGGTTTTGCATAAACTGTTT TACAGTGATCAT

TTCTAATATACACCCCCTATTTATTAATTATAACATAATTTTTTGTTAAATTTAAAA TAAACTTTTTTAT

TTTAAAAAATTATTAACCCCTAACGTGAATGATAACTATCACGTTAGGGTCAACTTT ATTATAAGCTAA

TTCGAATATATTGATTACTTGTAACCAGTAATCCAATTACTGAAAATGATGCTCTCA TAATCTGAATAT

CCGTCATTACCGAGTTGATAATCTTTGTTTCAGAGTCAGGAACATATTTCTTTTCTT TAAGATCATAAAT

CATTTTATTGTTAATACAACTCTCAACAGTTTCATATACTTCTTCATCGCTAAATAA TTGAGAGTTCTTT

AATACAATTGCATATGTTTCTTTAAATGCAGAATATACTAGTTGTAACAATACTTTA TCTACTTCAGTT

AAACTTTCTTCATTATCAATAATATCTTTAATTACTTTTGGAATTGAAATATTTCCT CCCGGAATATAAC

CGTAATCTAAAGCAGATCTACATGCAAAGATAGAATCTTCCAAGAGATATTTACGAG TATCACGTTCC

AATTCAGATTTACCACCAATAAATAACGTAGCTACTTTAGAAAGTAATCTAGCTTTA CGATTCTCTAAT

TTAAAGATTTCAGAATCTACACCTTTTTGATATACGTCTAAATTCTTTAAATCTTGA ATATTAAGGTCA

ATTAATTCAATTCGAGCATCTAATTCTTCTTGATGATACTCTCCCTTAATAAATTGA GTTGATCCACCA

GTCATCGTTACTGTTTCACAACGACCAATATGTTCACCATAAAATTGAGCGTTATTT GTTTTACTTAAG

ATAAATAAGTCTTCAAAACCTTCTTTACCTTTTTTAGTATTAATCTGAGTTCCTAAG TATATTGCTAAGT CTTCGAATTCTTCTTTACGAGTTCTAGCGGGAAAGTCTGTAGCTGCAATTTCTAGGGATA CTCTGGTAT

TATTGATCTTTTGAATCTTCATAAAGTCAATAAATTCCGGTCTATATTCCTTCGCAA CAATAACTAGAC

TTTTACCATTACCGCATACCTGACCAATAAGATGGGCAAAGAAATCAATATCCGTCT TATCTAAACAT

GAATCAGTAATAAATACATAAGGTTCTTTGAACATTGCTTCAATCTTATTTGGTTTA TTTGCAAAGATA

GGGTCAACATACCCACGACTAGTTTCAATACCATTTACAATTTCAAATGTATCCTCT TCAGAAGTAGAT

TTATCTAAATAAATAAATCCTCGTTTACCAATTTGTTTATAGATATTATAAATAATA TTTCCGTCTTTTT

CATCATTGTTGTTAGATACGGTTGCAATATTACGGAGAATCTCAAAGTTATCTTCAT TAATAGGAATTG

_{ATTTTTCTTTTAATTTCTTTTCAATCAGTTCACCAACATTATTTAATGAATTAAT GATTTCTTTCTTAGGA}

AGCTTACCTAAGAATTGTGAACGATCATTAACCATTGGTTCTAATTGATTATATAAT TCATTACTAACC

ACTACTGAAGAAGTTGATCCATCACCAACCTCTTGCACTAATGATCTTGAAATAGTC TTAATATTATTC

AGAAAAGTAGTACTAATAGTATTGTTAAAACGAATCTTGTCTAAAATTGTGAATCCA TCTTTAGAGAT

CTTAGAACCATATAAATTATCTTCTAGAATAGTTGTAGATCCATAATATCCTAAGGA TTTAGAAAGAAT

ATCACTAATACTATTAAGTGTTTCTTTAGCAATTTTTTGATATACTTCATCAGAAAT TACATTGCTTTCT

ACAATATCAATTTTTTCCTTAGGTTCAAGAATTCTTGAAATTTGATCTTTAATAATA TTGCTCATACACT

TTTCCACGCTGCTATATAAATTAGTGAATTTAATTTAATTCACAAGAATTTAATCAA CTTCGTCAACAA

GTTTCTTATAAATTCACAAAAAGTGAAAATACAGAGGAAAACTCTCTTAAGTTATAA TGGGTTTAGCC

AACCCTTTCTGCATATATTTTTAAATTACATGCAGAATTATAATCTCTATCCATCAC TTCATTACATTGA

TCACATGTATATAATCTATCCGAAAGTTTCATTTTTTTATCATTTTCTTTTTTATAT CCACAACAACTAC

AAATTTGAGTTGATGGAAACCATCTATCTGCAATAATTAAGGTATTTCCATATAAAA TACTTTTATATT

GTAATTGAACTTTAAAACGATAAAATAAAGACCGTGATATAGATTTAGATATTTTTC GGTTAGATAAC

ATTCCTTTAACATTTAAATCTTCTATACATATAGTGTGATAATTTTTAATAACGTAA GAAGTAAACTTA

TGCAGCCAATCATCTTGTATATTTTGTATTTTCAAATAAATATTTTGAAGTTTGATT TTCACTTTATTAT

ATTTATTCGAATTATTGACTTTTCTAGACAAGATTTTTTGGTATAAAGAAATTTTCT TATATAATGGAAT

TAAATTTTTTAAAGGACTATTAAATCGGTGATTTTCTTCACTTATATCAAAATGACC AATATTTGCATC

AATTCCAACTGTCGGAAGATTTTGATTTGAATGATACATACTATCATCAGTATCAAT ACAGAAAGAAG

CAAAATACTGATTTGCTCTTTTTGTAATTGTACATATTTTAATATCACCATTAAATC GTATCGATTCAGA

CATTTTTACACCATATTTAAATTTAGGTAAAAATAATCGATTATTAATAATCCTTAT TGTACTTTCGGCT

TTTCGATTAATCGTAAATGAACTTTTTGCTTTTCGTTTATTTTTGAATTTAGGTTTA CCTGAATTAGATG

TAAAAAATCTCTTCCAACCATATGCCATATTTTTACAAGCATTATCAAAAATATTTG GGGGAAAATTAT

CCCATTCAGGTTTCAATTTCCTTTTATATTCGTCTCGCACTTTTCGTTCATTAGGTT TATTGCCGTTAATG

TACATTTCATTCCATATATTCAAAGACACATTATATGAATATCTTGAATAATTGAAA AAATCTTTAAAT

TGTAACTGCATTGTTTTGTTAGGATAGATTCTGATTTTTTGACTTATTATCATCTAA ATCATCCCTTAAA

_{GTTTTTTTATATTTTCGTAATCCGTATAATCGGCTAGAAAATACATGAATAATTG TCATAAGATCATCA}

ACTAGTTCTTTTTCAGGAGAAGAACTTTCTAAATTAATTACAGTTAGTGTTGTTCCA TTAACTTTACATC

TTTCTTCAATAAGTTCAAAACCAAAACGAGTTAGTCGATCTTTATATGTTATAATAA GTTCTGATACTT

CTTGGTTTTCTATCATGTCAATTAATTTTAAAAAATTCTTTCGTTTAAAATTAATTC CGGATGCAATATC

TGAAAGATAAATATTAACAGGTTTTCCACTATTAACTGAAAATGTTTCAATAGATTG TCGTTGGTTTTC AAGTTCTTTCTTTTGGTTACTAGTTGAAACTCGATAATATGCTACAATTTTTCTTTTTTC TTCAGGTTTG ATATTATTAGTTAGTTCAAAATAATCATCAACCATTTCGTCAGTATAATACTTTAGGCGT CCTTTTCGA ATAGGTTTAATTATTTTTTCCTTTTCTAATGTTTCTAGTTTTTTCTTTGATATACGTAAT TTCATTCTAAA TTCATCAGAACGCATAACCATTTAAAACACACTCCTTTTTAATTTATATTATATTGTTAC ATTAAAATAT AAATTAAAGTGAAAAAGAGTGAAACTAGATGATATTCATAATAAGTCGGCTAAATTAAAT TCTTATTA TAATTCCCAATTTTGTGTTTCCACATTGGTTAAATAGCAGGACTATATCATAACCTATAA TATTATAGG TCCCTCGTACTTCCCTTTCGGTACTCTACTTGCTTCGTATAGATATCTCAATCTATCTTA TTCACCATAT AGGTGTTACATTTATTATTTGCTTTCGATAGTCTCTGAACGTTCACCCATCAAGTGGGAG CTTCGCTGC TAGATTTTCCATTAGTCCACCCTTAGCACTACGTTTTCTAAGGTTCACATTATTACTTCA CTTAGACACT GATAGGTTTTATTTCAGCTTAGGTAATCTTAAAGAGTTTTTTCTGTCTTTCGACTGCATT CACGCTTACC GTTACCAGTTACGTTGTAGCCCTTTAAGCTTTAGGAGTTTACAAGCAATTCACAAGGTTT CGCATACAT CTTTACAGATATATGGGAGTTTTGAATACAGGTTAATTTAATTTATATTTTAAACTAAAC TCATTTAAA ATCAATTAAACCATTACTGCTTCTTTTCTCCACTTTTTTATTTTATTATAATTGAAAGTA CATTGTCATTT TCAATAATACAATCGAATTCTTCGATAAAGGTATACATCTTAATATAATCTTTACATGAA TCAAGATCA ATATAATTATTAAATTTTAAGGATACTTTTTTAAATTGTCTAATTTCTTCATCTTTGGAA GTATTGTTAA ATCCTTTGATGATATTAAATGAAAATTTCTCTTCAAGATCATATAGTAGTAAATTAAGCT TTAATCCGA ATTCAGAATGCTTAAGTGAATCATAATAATTGTCTTCATCATAATCCCCATTCTTTTCGG TAAGTTTATT ATAAAATTTAAAATTATCGGTATTAATATTCATTAAACTTTCACCACGCTTTCTTAATTT GCCATAATA ACTCAACTGGACTATTAGTATTTACCATTTATCGGACTTAGATATCCATGGTCTGGTTTA CCTGTTGTAT TTTCATTAGGAGAAGAAGAGGTTCCTCCATTATAGAGATTTCTCAGTTCAGCTTCTTGCC TTTTATGTTT TTCAGCAATATCCTCTTCTTTAACTTCTCTAAGTCCTAATAATAGATACATTTCAGTGTT CATGATATCG TTTAGACTTAATTTACCTTCAAATAACTCTAATAAATATAGTATATCTTTAGAATCATTC AATACTTTCT TTTCGATAATCATTGAACCACTACTATTTTTCTCATCTACTGCTGAAGCTCCAGTTGAGT T

Example 10. Determining the Host Range of LPJP1.NL

[0209] The inclusivity of LPJP1.NL was determined using several commercially available L. grayi strains. Overnight cultures of each strain were diluted in BHI media to either a high burden (ODeoo of 0.2) or a low burden (1000 CFU/mL). 100 pL of each dilution was added to a well of a 96-well plate and infected with 10 pL of LPJP1.NL at 1.2 x 10 ⁷ pfu/mL. As done previously, infected wells were incubated for 4 h at 30 °C before the addition of 65 pL of luciferase detection solution. RLU values were obtained for each sample on the GloMax Navigator as described above. Samples were evaluated using a threshold of 190 RLU, which was approximately twice the signal from background (BHI media control). [0210] The exclusivity of LPJP1.NL was determined using both other Listeria species and a multitude of Gram -positive and Gram -negative genera. To assess the possibility of even minute signal production, a high bacterial burden was selected for testing. To this end, 100 pL of overnight culture was directly added to a 96-well plate and infected with 10 pL of LPJP1.NL at 1.2 x io ⁷ pfu/mL. As done previously, infected wells were incubated for 4 h at 30 °C before the addition of 65 pL of luciferase detection solution. Luminescence was measured and analyzed as described above for inclusivity assays.

Example 11. Inclusivity of LPJP1.NL Detection

[0211] Based upon plaque formation and the limit of detection, LPJP1.NL was clearly capable of infecting the L. grayi subsp. grayi strain ATCC 19120. However, it was not known whether or not this bacteriophage could broadly infect other L. grayi strains. Although the number of strains commercially available for testing is limited, four additional strains of L. grayi were obtained, including members of the only other subspecies L. grayi subsp. murrayi. Cultures of each strain were diluted to a low burden (approximately 100 CFU) or a high burden (ODeoo of 0.2) and infected with LPJP1.NL for 4 h. A cutoff of 190 RLU, approximately two times background, was chosen to distinguish between positive and negative detection for all inclusivity and exclusivity testing. Using this method, all five L. grayi strains were successfully detected at both low and high burdens, indicating infection and subsequent NANOLUC® production (Table 4). As expected, the use of stationary phase bacterial cells resulted in reduced signal compared to the limit of detection assay results for 100 CFU. Despite this decrease, LPJP1.NL was capable of infecting and detecting low burdens of all tested L. grayi strains, including representatives of both known subspecies.

Table 4. Inclusivity of LPJP1.NL Detection

¹ Strains were obtained from ATCC and each strains identification number is provided. ² Stationary phase cultures of each strain were diluted to the indicated colony forming unit (CFU) or optical density (ODeoo) prior to a 4 h infection at 30 °C with LPJP1.NL. ³ Detected luminometer signal as relative light units (RLU). Positive (Pos.) and negative (Neg.) detection was determined for each sample using a threshold of 190 RLU, approximately twice media background.

Example 12. Specificity of LPJP1.NL Detection Across Other Listeria Species

[0212] Many large characterized Listeria phage of the Myoviridae family, such as Pl 00 and A511, are capable of infecting multiple Listeria species, dependent on serovar (Klumpp, J.; et al., Bacteriophage 2013, 3, e26861; Habann, M., et al., Mol Microbiol 2014, 92, 84-99). While LPJP1.NL had demonstrated coverage across several L. grayi strains, the ability of this phage to infect other Listeria species was of significant interest. An exclusivity panel of 150 Listeria strains was assembled, consisting of 14 species and 12 different serovars. Due to commercial availability and the public health importance of L. monocytogenes, 106 strains of this species were included. In order to assess exclusivity, overnight stationary phase cultures of each strain were directly infected with LPJP1.NL for 4 h. This was expected to represent a significant bacterial burden and allow detection of even limited infection. Despite this burden, no strain in this Listeria panel yielded a positive result for NANOLUC® production, as defined by the 190 RLU threshold (Table 5). RLU data and source of each strain are provided (Table 6). The lack of any substantial signal over background from these strains suggests that LPJP1.NL is incapable of infecting other Listeria species besides L. grayi.

Table 5. Exclusivity of LPJP1.NL in Listeria Species Besides L. grayi

Bacteria ¹ Positives / Total Strains ²

Listeria aquatica 0/1

Listeria booriae 0/1

Listeria fleischmannii 0/1

Listeria floridensis 0/1

Listeria grandensis 0/1

Listeria innocua 0/21

Listeria ivanovii 0/6

Listeria marthii 0/2

Listeria monocytogenes 0/106

Listeria newyorkensis 0/1

Listeria riparia 0/1

Listeria seeligeri 0/4

Listeria welshimeri 0/4

Summary 0 / 150 ¹ Stationary phase overnight cultures were infected for 4 h at 30 °C with LPJP1.NL. ² Positive detection was determined for each sample using a threshold of 190 relative light units (RLU). Individual RLU values and strain information are provided in (Table 6).

Table 6. RLU for Exclusivity of LPJP1.NL in Listeria Species Besides L. grayi

Bacteria Strain Source ¹ Serovar ² RLU ³

Listeria aquatica FSL S10-1188 FSL 64

Listeria booriae FSL A5-0281 FSL 125

Listeria fleischmannii FSL F6-1016 FSL 98

Listeria floridensis FSL S10-1187 FSL 166

Listeria grandensis FSL F6-0971 FSL 67

Listeria innocua 33090 ATCC 6a 69

Listeria innocua BAA-680 ATCC 6a 49

Listeria innocua 33091 ATCC 6b 78

Listeria innocua 43547 ATCC 6b 84

Listeria innocua 51742 ATCC 50

Listeria innocua BAA-349 ATCC 37

Listeria innocua 9 UGA 73

Listeria innocua 15 UGA 61

Listeria innocua 16 UGA 69

Listeria innocua 18 UGA 54

Listeria innocua 72 UGA 56

Listeria innocua 80 UGA 60

Listeria innocua 92 UGA 81

Listeria innocua Silliker 9 UGA 90

Listeria innocua Silliker 9 NAR UGA 85

Listeria innocua Silliker 16 UGA 61

Listeria innocua Silliker 16 NAR UGA 58

Listeria innocua Silliker 23 NAR UGA 90

Listeria innocua Silliker 24 UGA 63

Listeria innocua Silliker 24 NAR UGA 72

Listeria innocua Sillikerl06 NAR UGA 56

Listeria ivanovii 19119 ATCC 80

Listeria ivanovii 49953 ATCC 87

Listeria ivanovii BAA-678 ATCC 5 92

Listeria ivanovii BAA-753 ATCC 65

Listeria ivanovii 700402 ATCC 66

Listeria ivanovii 49954 ATCC 59

Listeria marthii FSL S4-120 FSL 58

Listeria marthii FSL S4-965 FSL 54

Listeria monocytogenes 19111 ATCC l/2a 35

Listeria monocytogenes 51772 ATCC l/2a 67

Listeria monocytogenes 51774 ATCC l/2a 71

Listeria monocytogenes 51775 ATCC l/2a 77

Listeria monocytogenes BAA-679 ATCC l/2a 70

Listeria monocytogenes BAA-2657 ATCC l/2a 52

Listeria monocytogenes BAA-2659 ATCC l/2a 55

¹ Strains were obtained from either the American Type Culture Collection (ATCC, Manassas, VA, USA), the Food Safety Laboratory of Cornell University (FSL, Ithaca, NY, USA), the University of Georgia (UGA, Athens, GA, USA), or Q Laboratories (Q Labs, Cincinnati, OH, USA). ² Serovar of each strain is indicated when provided by source. ³ RL

Example 13. Specificity of LPJP1.NL Detection Across Other Genera

[0213] To evaluate the specificity of LPJP1.NL for Listeria, an exclusivity panel of 26 Gramnegative and 19 Gram-positive strains was assembled. Representatives of 19 unique genera and 42 species were included. As done with Listeria species, overnight stationary phase cultures of each strain were infected with LPJP1.NL for 4 h. Unsurprisingly, no positive signal was detected from any of the 45 members of the exclusivity panel (Table 7). The absence of NANOLUC® production in these strains further supports the notion that LPJP1.NL is highly specific for L. grayi. LPJP1.NL was highly specific for L. grayi demonstrating no cross-reactivity with other Listeria species or bacterial genera (Tables 5,7). The narrow host range of LPJP1 may indicate a receptor unique to L. grayi.

Table 7. Exclusivity of LPJP1NANOLUC® in other Genera (non-Listeria)

¹ Strains were obtained from ATCC and each strain’s identification number is provided. ² Stationary phase overnight cultures were infected for 4 h at 30 °C with LPJP1.NL. Detected luminometer signal as relative light units (RLU). Positive (Pos.) and negative (Neg.) detection was determined for each sample using a threshold of 190 RLU, approximately twice media background.

Example 15. Specificity of Listeria-Specific Phages

[0214] The inclusivity of A511-3A, LMA8, LP-ES1, and LPJP1 for Listeria was assessed using several commercially available Listeria strains. Overnight cultures of each strain were diluted in BHI media to either a high burden (OD60 of ~0.2) or a low burden (1000 CFU/mL). 100 pL of each dilution was added to a well of a 96-well plate and infected with 10 pL of either LMA8.NL, LP-ESl.NL, A511-3A.NL, or LPJPl.NL at 1.2 x 107 pfu/mL. As done previously, infected wells were incubated for 4 h at 30 °C before the addition of 65 pL of luciferase detection solution. RLU values were obtained for each sample on the GloMax Navigator as described above. Samples were evaluated using a threshold of 190 RLU, which was approximately twice the signal from background (BHI media control). The inclusivity data for LMA8.NL is shown in Table 8. The inclusivity data for LP-ESl.NL is shown in Table 9. The inclusivity data for LMA8.NL A511-3A.NL is shown in Table 10. The inclusivity data for

LPJP1.NL is shown in Table 11.

TABLE 8. LMA8NANOLUC® Inclusivity

TABLE 9. LP-ES1NANOLUC® Inclusivity

TABLE 10. A511 -3 ANANOLUC® Inclusivity

TABLE 11. LPJP1NANOLUC® Inclusivity

Example 16. Specificity of Listeria-Specific Phage Cocktail [0215] To evaluate the specificity of a phage cocktail (A511-3A, LMA8, LP-ES1, JP1) for Listeria spp., an exclusivity panel of 26 Gram-negative and 19 Gram-positive strains was assembled. Representatives of 19 unique genera and 42 species were included. As done with Listeria species, overnight stationary phase cultures of each strain were infected with the phage cocktail for 4 h. The results from the exclusivity panel are shown in Tables 12 and 13. A cutoff of 190 RLU, approximately two times background, was chosen to distinguish between positive and negative detection for all inclusivity and exclusivity testing.

Table 12. Gram Negative Exclusivity

Table 13. Gram Positive Exclusivity

Example 17. Specificity of Listeria-Specific Phage Cocktail

[0216] The Listeria assay was validated for the detection of Listeria spp. on glaze ceramic (4” x 4” test area) and stainless steel (4” x 4” test area) surfaces. The validation consisted of an inclusivity and exclusivity evaluation and a matrix study. The Listeria assay was compared to the 2017 U.S. Food and Drug Administration Bacteriological Analytical Manual, Chapter 10 “Detection of Listeria monocytogenes in Foods and Environmental samples, and Enumeration of Listeria monocytogenes in Foods’" using an unpaired study design for ceramic (4” x 4” test area) and stainless steel (4” x 4” test area) surfaces. Final confirmation was obtained by Bruker MALDI Biotyper following AOAC OMA 2017.09. An alternate confirmation was also performed for all samples. This was performed by allowing the samples to continue enriching for a total of 24-28 hours at 35 ± 1 °C. The samples were thoroughly mixed and 100 pL of the sample was struck onto RAPID L. mono Agar and allowed to incubate for 24-28 hours at 37 ± 1 °C. The inclusivity and exclusivity evaluation evaluated two strains of Listeria seeligeri, two strains of Listeria welshimeri, one strain of Enterococcus faecalis, one strain of Enterococcus faecium, and one strain of Streptococcus pyogenes.

[0217] In the inclusivity study, four out of the four Listeria spp. strains evaluated were correctly detected, and all three exclusivity strains were correctly excluded. In the matrix study, the Listeria assay demonstrated no significant differences between presumptive and confirmed results or between candidate and reference method results for ceramic (4” x 4” test area) and stainless steel (4” x 4” test area) surfaces. The Listeria assay allowed for fast, reliable detection of Listeria on ceramic (4” x 4” test area) and stainless steel (4” x 4” test area) surfaces with instrument run time taking less than 10 minutes. [0218] No statistical difference was detected between the Listeria assay and the reference culture method in the U.S. Food and Drug Administration Bacteriological Analytical Manual Chapter 10 “Detection of Listeria monocytogenes in Foods and Environmental samples, and Enumeration of Listeria monocytogenes in Foods” (FDA/BAM Chapter 10) for ceramic (4” x 4”) and stainless steel (4” x 4”) surfaces (1).

Sample Preparation

[0219] Ceramic (4” x 4” test area) and stainless steel (4” x 4” test area) environmental surfaces were swabbed with an EZ Reach Polyurethane Sponge Sample using firm and even pressure 10 times vertically and horizontally. The swabs were placed back into the sampler bag discarding the plastic handle and stored at room temperature (20 - 25 °C) for 2 hours. Following the 2 hour storage, the samples were enriched with 20 mL of pre-warmed (35 ± 1 °C) BLEB, massaged by hand for 10-20 seconds, and incubated at 35 ± 1 °C for 20 - 24 hours.

Sample Infection

[0220] Following incubation enriched samples were removed from the incubator and mixed thoroughly by massaging the sponge for 10 - 20 seconds. Using a single channel pipettor and clean tip for each sample, 150 pL of enriched sample was transferred into a well of the 96-well plate. One tube containing the recombinant phage solution was used for each 8 well strip. The tube was flicked or supun to collect all of the solution at the bottom of the tube. 10 pL of the recombinant phage solution was then added to each sample in the 96-well plate and mixed completely and gently by pipetting up and down. The plate was covered and sealed to prevent evaporation and placed in a 30 ± 1 °C incubator for 4 hours.

Sample Lysis and Signal Reading

[0221] The substrate solution was pprepared by transferring the entire contents of assay buffer (500 pL) and lysis buffer (150 pL) tubes to the substrate tube (10 pL) and mixing. 65 pL of freshly prepared lysis/ luciferase master mix solution to each sample well and mix thoroughly by pipetting up and down. Once all the samples received the lysis/ luciferase substrate master mix solution, the sample plate was placed in the luminometer and read.

Interpretation and Test Result Report [0222] Samples having a reading value of 300 RLU or greater were considered positive for detection of Listeria. For a negative Listeria result, the reading value was less than 300 RLU.

Confirmation

[0223] Confirmation was also performed for all samples. For each surface test portion, the samples were allowed to continue enriching for a total of 24-28 hours at 35 ± 1 °C. The samples were thoroughly mixed and 100 pL of the sample was struck onto RAPID L. mono Agar and allowed to incubate for 24-28 hours at 37 ± 1 °C.

Inclusivity and Exclusivity Data

[0224] The inclusivity and exclusivity study evaluated two strains of Listeria seeligeri, two strains of Listeria welshimeri, one strain of Enterococcus faecatis. and one strain of Enterococcus faecium. and one strain of Streptococcus pyogenes. All cultures evaluated were propagated from a stock culture stored at -70 °C to trypticase soy agar with 5% sheep blood (SB A) and incubated for 24 ± 2 hours at 35 ± 1°C. After incubation of the target organisms, a single colony from SB A was transferred to a 9 mL aliquot of BLEB for 20-24 hours at 35 ± 1 °C. After incubation, each Listeria spp. strain was then diluted to 100 times the LOD50 of the Listeria assay. After incubation of the exclusivity organisms, each strain was transferred to a non-selective media and incubated under conditions for optimal growth. After incubation, each exclusivity organism was analyzed undiluted. All inclusivity and exclusivity strains were blind coded, randomized and analyzed using the Listeria assay follow package instructions. Test results were decoded and reported as either positive or negative.

[0225] The matrix study consisted of evaluating a total of 30 unpaired sample replicates of ceramic (4” x 4”) and stainless steel (4” x 4”) surface test areas. Within each sample set, there were 5 uninoculated samples (0 CFU/test portion), 20 low level inoculated samples (0.2-2 CFU/test portion) targeted to obtain fractional results, and 5 high level inoculated samples (2-10 CFU/test portion). All samples were analyzed by the PhageDx Listeria Assay following enrichment with pre-warmed (35 ± 1 °C) BLEB and incubated for 20-24 hours at 35 ± 1 °C, analysis was conducted after 20 hours. Regardless of presumptive results, all samples were culturally confirmed by the FDA/BAM Chapter 10 reference method. In addition, all samples were confirmed following the alternative confirmation described previously in “Materials and Methods”, subsection “Confirmation”. Final confirmation for all samples were obtained by Bruker MALDI Biotyper following AO AC OMA 2017.10.

Organism Preparation and Inoculation

[0226] For ceramic surfaces, 4” x 4” areas were inoculated with 0.25 mL of diluted L. innocua ATCC 43547 culture and sampled using sampling sponges premoistened in letheen broth. For stainless steel surfaces, 4” x 4” areas were inoculated with 0.25 mL of diluted L. monocytogenes 4a CWD 1554. In addition to the L. monocytogenes culture, stainless steel surface was co-inoculated with a competitor organism, Enterococcus faecalis ATCC 29212, at 10 x the level of the target organism. All cultures utilized were propagated from a stock culture stored at -70 °C to SB A and incubated for 24 ± 2 hours at 35 ± 1°C. After incubation, a single colony from SB A was transferred to a 9 mL aliquot of BHI broth for 20-24 hours at 35 ± 1 °C. Each culture was then diluted to the target concentration by performing serial dilutions as 0.1% peptone water as the diluent. For the uninoculated test portions, sterile 0.1% peptone water was applied to the test area. Each surface was dried for 16-24 hours at room temperature (24 ± 2 oC) prior to sampling. To determine the inoculation level for the environmental surfaces, aliquots of each inoculum were plated onto Tryptic Soy agar (TSA) in triplicate.

[0227] For environmental samples, sponges were pre-moistened with 10 mL of DZE neutralizing broth. Following addition of DZE neutralizing broth surfaces were swabbed using firm and even pressure 10 times vertically and horizontally. All environmental samples were then stored at 22 ± 2 °C for 2 h ± 15 minutes. Swabs were enriched with 90 mL of BLEB, massaged by hand for 2 minutes and incubated at 30 ± 1 °C for 4 hours. Following 4 hours of incubation, selective supplements acriflavine (10 mg/L), sodium nalidixate (40 mg/L) and cycloheximide (50 mg/L) were added to each test portion and samples were re-incubated for 24- 48 hours.

[0228] After 24 hours of total incubation, the enriched samples were streaked to MOX agar plates and incubated at 35 ±1 °C for 24-48 hours. In addition to MOX, each enriched sample was streaked to the chromogenic selective agar Brilliance Listeria Agar (BLA) and incubated at 37 ± 1 °C for 24 ± 2 hours. The enriched samples were re-incubated for an additional 24 hours at 30 ± 1 °C and then streaked to a second MOX and BLA agar plate which was incubated for 24-48 hours at 35 ± loC and 37 ± 1 °C for 24 ± 2 hours, respectively. MOX and BLA agar plates were examined for suspect colonies, and if present, at least 5 colonies were streaked to Tryptic Soy Agar containing 0.6% yeast extract (TSA/YE). The TSA/YE plates were incubated at 35 ± 1°C for 24-48 hours and then examined for purity. Pure colonies were tested for catalase reactivity and a Gram stain was conducted. A pure Listeria monocytogenes colony was transferred to Trypticase Soy Broth containing 0.6% yeast extract (TSB/YE). The TSB/YE cultures were incubated at 25 ± 1 °C overnight, or until the broth was turbid, indicating sufficient growth. Catalase-positive organisms were stabbed into SB A plates and incubated at 35 ± 1°C for 24-48 hours. The TSB/YE tubes incubated at 25 ± 1 °C were used to prepare a wet mount slide to determine motility pattern. After incubation, the SBA plates were examined for hemolysis. Final confirmation was conducted using Bruker MALDI Biotyper following AO AC OMA 2017.10.

Listeria Assay

[0229] Ceramic (4” x 4” test area) and stainless steel (4” x 4” test area) surfaces were enriched and incubated according to the protocol described above. Following incubation, all samples were analyzed using the Listeria assay following product instructions. All sample regardless of presumptive results were culturally confirmed by the FDA/BAM Chapter 10 reference method. Final confirmation for all samples was obtained by Bruker MALDI Biotyper following AOAC OMA 2017.09.

For the inclusivity and exclusivity study of the four strains of Listeria spp. tested, all seven were correctly included, and for the three exclusivity strains all three were correctly excluded. A summary of the inclusivity exclusivity results are presented in Table 14. For ceramic (4” x 4” test area) and stainless steel (4” x 4” test area) environmental samples the inoculum recovered for the target L. innocua and L. monocytogenes stains fell withing the targeted levels, while the competitor organism was at a level at least 10 times higher.

Table 14. Results of the Inclusivity and Exclusivity Study-Listeria Assay