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Title:
METHODS TO FABRICATE, MODIFY, REMOVE AND UTILIZE FLUID MEMBRANES
Document Type and Number:
WIPO Patent Application WO/2014/132139
Kind Code:
A3
Abstract:
One aspect of the invention provides a method for fabrication of a membrane on a surface. The method includes: providing a surface interfacing two environments, wherein one of the environments is a liquid; providing a flow-recirculating fluidic device having channel exits in the liquid environment in proximity of the surface; and delivering locally one or more processing solutions. The one or more processing sources including one or more membrane sources adapated and configured to form a membrane on the surface.

Inventors:
AINLA ALAR (SE)
GOZEN IREP (SE)
JESORKA ALDO (SE)
SHAALI MEHRNAZ (SE)
Application Number:
PCT/IB2014/001089
Publication Date:
April 02, 2015
Filing Date:
January 19, 2014
Export Citation:
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Assignee:
AVALANCE BIOTECH AB (SE)
International Classes:
B01L3/02; B01L3/00; G01N33/543; G01N33/544; G01N35/10
Other References:
SMITH KATHRYN ET AL: "Micropatterned fluid lipid bilayer arrays created using a continuous flow microspotter", ABSTRACTS OF PAPERS AMERICAN CHEMICAL SOCIETY, vol. 237, March 2009 (2009-03-01), & 237TH NATIONAL MEETING OF THE AMERICAN-CHEMICAL-SOCIETY; SALT LAKE CITY, UT, USA; MARCH 22 -26, 2009, pages 408 - COLL, XP002733838, ISSN: 0065-7727
ROBERT D LOVCHIK ET AL: "Multilayered microfluidic probe heads", JOURNAL OF MICROMECHANICS & MICROENGINEERING, INSTITUTE OF PHYSICS PUBLISHING, BRISTOL, GB, vol. 19, no. 11, 1 November 2009 (2009-11-01), pages 115006, XP020168801, ISSN: 0960-1317
AINLA A ET AL: "Hydrodynamic flow confinement technology in microfluidic perfusion devices", MICROMACHINES 2012 MDPI AG CHE, vol. 3, no. 2, 2012, pages 442 - 461, XP002733839, DOI: 10.3390/MI3020442
KAIGALA G V ET AL: "Microfluidics in the "open Space" for performing localized chemistry on biological interfaces", ANGEWANDTE CHEMIE - INTERNATIONAL EDITION 20121105 WILEY-VCH VERLAG DEU, vol. 51, no. 45, 5 November 2012 (2012-11-05), pages 11224 - 11240, XP002733840, DOI: 10.1002/ANIE.201201798
AINLA A ET AL: "A microfluidic pipette for single-cell pharmacology", ANALYTICAL CHEMISTRY 20100601 AMERICAN CHEMICAL SOCIETY USA, vol. 82, no. 11, 1 June 2010 (2010-06-01), pages 4529 - 4536, XP002733841, DOI: 10.1021/AC100480F
Attorney, Agent or Firm:
LANDRY, Brian, R. et al. (Center Square West1500 Market Street, 38th Floo, Philadelphia PA, US)
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