Title:
METHODS TO ISOLATE EXTRACELLULAR VESICLES IN BIOFLUIDS FOR BIOMARKER DISCOVERY AND DISEASE DIAGNOSIS
Document Type and Number:
WIPO Patent Application WO/2017/062901
Kind Code:
A3
Abstract:
EVs are connected to onset and progression of numerous diseases and can be used for their diagnosis. Methods and platform technology to isolate EVs and detect intravesicle phosphoproteins from biofluids are discussed. Secreted extracellular vesicles in biofluids are effectively isolated and phosphoproteins are extracted for detection and identification as biomarkers for disease diagnosis using antibodies, mass spectrometry, or other like methods.
Inventors:
TAO ANDY (US)
ILYUK ANTON (US)
BAO NING (US)
ILYUK ANTON (US)
BAO NING (US)
Application Number:
PCT/US2016/056172
Publication Date:
May 26, 2017
Filing Date:
October 07, 2016
Export Citation:
Assignee:
TYMORA ANALYTICAL OPERATIONS LLC (US)
International Classes:
C12M1/42; C12N13/00; G01N27/00; G01N30/00; G01N33/50; H03K3/64
Domestic Patent References:
| WO2014107571A1 | 2014-07-10 | |||
| WO2010072410A2 | 2010-07-01 |
Foreign References:
| US20080160602A1 | 2008-07-03 | |||
| US20140315195A1 | 2014-10-23 | |||
| US20080231337A1 | 2008-09-25 |
Attorney, Agent or Firm:
D'HUE, Cedric (US)
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