Title:
METHODS OF TREATING COCHLEAR SYNAPTOPATHY
Document Type and Number:
WIPO Patent Application WO/2018/111926
Kind Code:
A3
Abstract:
The present application describes the use of gamma secretase inhibitors and gamma secretase modulators for the treatment of cochlear synaptopathy.
Inventors:
LORRAIN DANIEL (US)
POON MICHAEL (US)
STEBBINS KARIN (US)
POON MICHAEL (US)
STEBBINS KARIN (US)
Application Number:
PCT/US2017/065892
Publication Date:
July 26, 2018
Filing Date:
December 12, 2017
Export Citation:
Assignee:
SIROCCO THERAPEUTICS INC (US)
International Classes:
A61K31/427; A61K31/195; A61K31/4985; A61K31/55
Foreign References:
| US20150209367A1 | 2015-07-30 | |||
| US20150209406A1 | 2015-07-30 | |||
| US20110305674A1 | 2011-12-15 | |||
| US20120289558A1 | 2012-11-15 |
Other References:
RUOLUN QIU ET AL.: "A novel gamma secretase modulator: safety, tolerability, pharmacokinetics, and effects on plasma amyloid-b levels following single oral ascending doses in healthy volunteers, Poster Presentations", ALZHEIMER'S & DEMENTIA: THE JOURNAL OF THE ALZHEIMER'S ASSOCIATION, vol. 12, no. 7, July 2016 (2016-07-01), pages 611 - 612, XP029769821
Attorney, Agent or Firm:
MALLON, Joseph, J. (US)
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