Title:
METHODS OF TREATING DISEASE THROUGH THE ADMINISTRATION OF A MANZAMINE ANALOG OR DERIVATIVE
Document Type and Number:
WIPO Patent Application WO2005084157
Kind Code:
A3
Abstract:
A method of treating cancer, inflammatory disease or an infectious disease or condition in a subject in need of such treatment is disclosed. The method comprises administering to a subject an effective amount of a manzamine, or a rationally modified manzamine derivative or analog or an optical isomer or racemate or tautomer thereof or a pharmaceutically acceptable salt or prodrug thereof generated through optimized fermentation of a Micromonospora sp., extraction from sponges and then modified through semisynthesis.
Inventors:
HAMANN MARK T (US)
RAO KARUMANCHI VENKATESWARA (US)
PENG JIANGNAN (US)
RAO KARUMANCHI VENKATESWARA (US)
PENG JIANGNAN (US)
Application Number:
PCT/US2004/020742
Publication Date:
April 13, 2006
Filing Date:
June 28, 2004
Export Citation:
Assignee:
UNIV MISSISSIPPI (US)
International Classes:
A01N43/42; A61K31/44; A61K31/47
Domestic Patent References:
| WO1999059592A1 | 1999-11-25 | |||
| WO2002017917A1 | 2002-03-07 |
Foreign References:
| US6143756A | 2000-11-07 | |||
| US0485852A | 1892-11-08 | |||
| US4895854A | 1990-01-23 | |||
| US4895853A | 1990-01-23 | |||
| US6387916B1 | 2002-05-14 | |||
| US20020187999A1 | 2002-12-12 |
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