Title:
METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS
Document Type and Number:
WIPO Patent Application WO/2014/121343
Kind Code:
A1
Abstract:
The invention includes methods and compositions for treating mastitis in a subject. The method includes the step of administering, by intramammary delivery, a therapeutically effective amount of a polyether ionophore, or a therapeutically acceptable salt thereof, to the mammary gland of the subject.
Inventors:
PAGE STEPHEN (AU)
GARG SANJAY (AU)
GARG SANJAY (AU)
Application Number:
PCT/AU2014/000102
Publication Date:
August 14, 2014
Filing Date:
February 10, 2014
Export Citation:
Assignee:
LUODA PHARMA PTY LTD (AU)
PAGE STEPHEN (AU)
GARG SANJAY (AU)
PAGE STEPHEN (AU)
GARG SANJAY (AU)
International Classes:
A61K31/35; A61M5/178; A61P31/04
Domestic Patent References:
| WO2011150481A1 | 2011-12-08 |
Other References:
HEUER. C. ET AL.: "Effect of monensin on Blood Ketone Bodies, Incidence and Recurrence of Disease and Fertility in Dairy Cows", JOURNAL OF DAILY SCIENCE, vol. 84, no. 5, May 2001 (2001-05-01), pages 1085 - 1097, XP026990355
MCDOUGALL, S. ET AL.: "Production and Health of Pasture-Ped Dairy Cattle Following Oral Treatment with the Ionophore Lasalocid", JOURNAL OF DAIRY SCIENCE, vol. 87, no. 9, September 2004 (2004-09-01), pages 2967 - 2976, XP026970147
DUFFIELD, T. F. ET AL.: "A Meta-Analysis of the Impact of Monensin in Lactating Dairy Cattle. Part 3. Health and Reproduction", JOURNAL OF DAIRY SCIENCE, vol. 91, no. 6, June 2008 (2008-06-01), pages 2328 - 2341, XP026956588
ROGER BLOWEY; PETER EDMONDSON: "Mastitis control in dairy herds", 2010
"Treatment and Dry Cow Therapy", 2010, CAB INTERNATIONAL, pages: 196 - 197
MEANEY, W. J.: "Dry period teat seal.", VET REC., vol. 99, no. 2, 1976, pages 30
SMITH, A.; F. K. NEAVE ET AL., JOURNAL OF DAIRY RESEARCH, vol. 34, no. 01, 1967, pages 47 - 57
NAUJOKAT; STEINHART, J BIOMED BIOTECHNOL, 2012, pages 950658
LIU; J. W. WESTLEY: "Biology", vol. 1, 1982, MARCEL DEKKER INC, article "Polyether Antibiotics. Naturally Occurring Acid lonophores", pages: 43 - 102
GILBERT ET AL., CLINICAL INFECTIOUS DISEASES, vol. 50, no. 8, 2010, pages 1081 - 1083
HEUER ET AL., J. DAIRY SCI., vol. 84, no. 5, 2001, pages 1085 - 97
MCDOUGALL ET AL., J. DAIRY SCI., vol. 87, no. 9, 2004, pages 2967 - 76
DUFFIELD ET AL., J. DAIRY SCI., vol. 91, no. 6, 2008, pages 2328 - 41
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 25999-31-9
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 17090-79-8
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 53003-10-4
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 55134-13-9
"Remington's Pharmaceutical Sciences", 1985, MACK PUBLISHING COMPANY, pages: 1418
LAVEN, R.: "Clinical forum: choosing mastitis treatment in the lactating cow: selling or science?", UK VET: LIVESTOCK, vol. 13, no. 4, 2008, pages 29 - 36
MCDOUGALL, S.: "Efficacy of two antibiotic treatments in curing clinical and subclinical mastitis in lactating dairy cows", N. Z. VET. J., vol. 46, no. 6, 1998, pages 226 - 232
MCDOUGALL, S.: "Prevalence of clinical mastitis in 38 Waikato dairy herds in early lactation", N. Z. VET. J., vol. 47, no. 4, 1999, pages 143 - 149
MCDOUGALL, S.; K. E. AGNEW; R. CURSONS; X. X. HOU; C. R. COMPTON: "Parenteral treatment of clinical mastitis with tylosin base or penethamate hydriodide in dairy cattle", J. DAIRY SCI., vol. 90, no. 2, 2007, pages 779 - 789, XP026955731
MCDOUGALL, S.; D. G. ARTHUR; M. A. BRYAN; J. J. VERMUNT; A. M. WEIR: "Clinical and bacteriological response to treatment of clinical mastitis with one of three intramammary antibiotics", N. Z. VET. J., vol. 55, no. 4, 2007, pages 161 - 170
PETROVSKI, K.; C. HEUER; T. PARKINSON; N. WILLIAMSON: "The incidence and aetiology of clinical bovine mastitis on 14 farms in Northland, New Zealand", N. Z. VET. J., vol. 57, no. 2, 2009, pages 109 - 115
SHUM, L. W. C.; C. S. MCCONNEL; A. A. GUNN; J. K. HOUSE: "Environmental mastitis in intensive high-producing dairy herds in New South Wales", AUST. VET. J., vol. 87, no. 12, 2009, pages 469 - 475
See also references of EP 2953624A4
MCDOUGALL, S. ET AL.: "Production and Health of Pasture-Ped Dairy Cattle Following Oral Treatment with the Ionophore Lasalocid", JOURNAL OF DAIRY SCIENCE, vol. 87, no. 9, September 2004 (2004-09-01), pages 2967 - 2976, XP026970147
DUFFIELD, T. F. ET AL.: "A Meta-Analysis of the Impact of Monensin in Lactating Dairy Cattle. Part 3. Health and Reproduction", JOURNAL OF DAIRY SCIENCE, vol. 91, no. 6, June 2008 (2008-06-01), pages 2328 - 2341, XP026956588
ROGER BLOWEY; PETER EDMONDSON: "Mastitis control in dairy herds", 2010
"Treatment and Dry Cow Therapy", 2010, CAB INTERNATIONAL, pages: 196 - 197
MEANEY, W. J.: "Dry period teat seal.", VET REC., vol. 99, no. 2, 1976, pages 30
SMITH, A.; F. K. NEAVE ET AL., JOURNAL OF DAIRY RESEARCH, vol. 34, no. 01, 1967, pages 47 - 57
NAUJOKAT; STEINHART, J BIOMED BIOTECHNOL, 2012, pages 950658
LIU; J. W. WESTLEY: "Biology", vol. 1, 1982, MARCEL DEKKER INC, article "Polyether Antibiotics. Naturally Occurring Acid lonophores", pages: 43 - 102
GILBERT ET AL., CLINICAL INFECTIOUS DISEASES, vol. 50, no. 8, 2010, pages 1081 - 1083
HEUER ET AL., J. DAIRY SCI., vol. 84, no. 5, 2001, pages 1085 - 97
MCDOUGALL ET AL., J. DAIRY SCI., vol. 87, no. 9, 2004, pages 2967 - 76
DUFFIELD ET AL., J. DAIRY SCI., vol. 91, no. 6, 2008, pages 2328 - 41
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 25999-31-9
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 17090-79-8
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 53003-10-4
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 55134-13-9
"Remington's Pharmaceutical Sciences", 1985, MACK PUBLISHING COMPANY, pages: 1418
LAVEN, R.: "Clinical forum: choosing mastitis treatment in the lactating cow: selling or science?", UK VET: LIVESTOCK, vol. 13, no. 4, 2008, pages 29 - 36
MCDOUGALL, S.: "Efficacy of two antibiotic treatments in curing clinical and subclinical mastitis in lactating dairy cows", N. Z. VET. J., vol. 46, no. 6, 1998, pages 226 - 232
MCDOUGALL, S.: "Prevalence of clinical mastitis in 38 Waikato dairy herds in early lactation", N. Z. VET. J., vol. 47, no. 4, 1999, pages 143 - 149
MCDOUGALL, S.; K. E. AGNEW; R. CURSONS; X. X. HOU; C. R. COMPTON: "Parenteral treatment of clinical mastitis with tylosin base or penethamate hydriodide in dairy cattle", J. DAIRY SCI., vol. 90, no. 2, 2007, pages 779 - 789, XP026955731
MCDOUGALL, S.; D. G. ARTHUR; M. A. BRYAN; J. J. VERMUNT; A. M. WEIR: "Clinical and bacteriological response to treatment of clinical mastitis with one of three intramammary antibiotics", N. Z. VET. J., vol. 55, no. 4, 2007, pages 161 - 170
PETROVSKI, K.; C. HEUER; T. PARKINSON; N. WILLIAMSON: "The incidence and aetiology of clinical bovine mastitis on 14 farms in Northland, New Zealand", N. Z. VET. J., vol. 57, no. 2, 2009, pages 109 - 115
SHUM, L. W. C.; C. S. MCCONNEL; A. A. GUNN; J. K. HOUSE: "Environmental mastitis in intensive high-producing dairy herds in New South Wales", AUST. VET. J., vol. 87, no. 12, 2009, pages 469 - 475
See also references of EP 2953624A4
Attorney, Agent or Firm:
WRAYS (West Perth, Western Australia 6005, AU)
Download PDF:
Previous Patent: METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS
Next Patent: STAIR MODULES WHICH CO OPERATE TO FORM A TEMPORARY STAIR CASE
Next Patent: STAIR MODULES WHICH CO OPERATE TO FORM A TEMPORARY STAIR CASE