Title:
METHODS AND USES FOR REDUCING AN ALLERGIC RESPONSE IN A SUBJECT
Document Type and Number:
WIPO Patent Application WO/2015/054217
Kind Code:
A3
Abstract:
The present invention relates to the therapeutic use of antigens derived from grass pollen that have shown to down regulate the specific IL-5 response in grass allergic patients while undergoing specific immunotherapy. Specific antigens, such as proteins, peptides and peptide combinations have been identified with high IL-5 modulating activity.
Inventors:
SETTE ALESSANDRO (US)
PETERS BJOERN (US)
SCHULTEN VÉRONIQUE (US)
PETERS BJOERN (US)
SCHULTEN VÉRONIQUE (US)
Application Number:
PCT/US2014/059449
Publication Date:
October 08, 2015
Filing Date:
October 07, 2014
Export Citation:
Assignee:
JOLLA INST ALLERGY IMMUNOLOG (US)
International Classes:
A61K39/36
Domestic Patent References:
| WO2013119863A1 | 2013-08-15 |
Other References:
VRTALA SUSANNE ET AL: "CDNA cloning of a major allergen from Timothy grass (Phleum pratense) pollen: Characterization of the recombinant PhI p V allergen", THE JOURNAL OF IMMUNOLOGY, THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, vol. 151, no. 9, 1 November 1993 (1993-11-01), pages 4773 - 4781, XP002563140, ISSN: 0022-1767
V. SCHULTEN ET AL: "Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 110, no. 9, 26 February 2013 (2013-02-26), pages 3459 - 3464, XP055164674, ISSN: 0027-8424, DOI: 10.1073/pnas.1300512110
V. SCHULTEN ET AL: "Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 110, no. 9, 26 February 2013 (2013-02-26), pages 3459 - 3464, XP055164674, ISSN: 0027-8424, DOI: 10.1073/pnas.1300512110
Attorney, Agent or Firm:
BUCK, B., Logan et al. (Bank of America Plaza101 South Tryon Street, Suite 400, Charlotte North Carolina, US)
Download PDF:
Previous Patent: LUMINAIRES HAVING BATWING PHOTOMETRIC DISTRIBUTION
Next Patent: CONTEXTUAL INSIGHTS AND EXPLORATION
Next Patent: CONTEXTUAL INSIGHTS AND EXPLORATION