METHYLATION MARKERS FOR DIAGNOSING CANCER

CROSS-REFERENCE

[0001] This application claims the benefit of U.S. Provisional Application No. 62/569,459, filed October 6, 2017, and U.S. Provisional Application No. 62/673,593, filed May 18, 2018, which each of the applications is incorporated herein by reference in its entirety.

BACKGROUND OF THE DISCLOSURE

[0002] Cancer is a leading cause of deaths worldwide, with annual cases expected to increase from 14 million in 2012 to 22 million during the next two decades (WHO). Diagnostic procedures for liver cancer, in some cases, begin only after a patient is already present with symptoms, leading to costly, invasive, and sometimes time-consuming procedures. In addition, inaccessible areas sometimes prevent an accurate diagnosis. Further, high cancer morbidities and mortalities are associated with late diagnosis.

SUMMARY OF THE DISCLOSURE

[0003] In certain embodiments, disclosed herein is a method of selecting a subject suspected of having cancer for treatment, comprising: (a) contacting treated DNA with at least one probe from a probe panel to generate an amplified product, wherein the at least one probe hybridizes under high stringency condition to a target sequence of a eg marker selected from Table 1, Table 2, Table 7, Table 8, or Table 13, and wherein the treated DNA is processed from a biological sample obtained from the subject; (b) analyzing the amplified product to generate a methylation profile of the eg marker; (c) comparing the methylation profile to a reference model relating methylation profiles of eg markers from Tables 1, 2, 7, 8, and 13 to a set of cancers; (d) based on the comparison of step c), determining: (i) whether the subject has cancer; and (ii) which cancer type the subject has; and (e) administering an effective amount of a therapeutic agent to the subject if the subject is determined to have cancer and the cancer type is determined.

[0004] In certain embodiments, disclosed herein is a method of detecting the methylation status of a set of eg markers, comprising: (a) processing a biological sample obtained from a subject with a deaminating agent to generate treated DNA comprising deaminated nucleotides; (b) contacting the treated DNA with at least one probe that hybridizes under high stringency condition to a target sequence of a eg marker from Table 1, Table 2, Table 7, Table 8, Table 13, Table 14, or Table 20; and (c) quantitatively detecting the methylation status of the eg marker, wherein said detection comprises a real-time quantitative probe-based PCR or a digital probe- based PCR. [0005] Disclosed herein, in certain embodiments, is a method of detecting a methylation pattern of a set of biomarkers in a subject suspected of having a cancer, the method comprising: (a) processing an extracted genomic DNA with a deaminating agent to generate a genomic DNA sample comprising deaminated nucleotides, wherein the extracted genomic DNA is obtained from a biological sample from the subject suspected of having a cancer; and (b) detecting the methylation pattern of one or more biomarkers selected from Table 1, Table 2, Table 7, Table 8, Table 13, Table 14, or Table 20 from the extracted genomic DNA by contacting the extracted genomic DNA with a set of probes, wherein the set of probes hybridizes to the one or more biomarkers, and perform a DNA sequencing analysis to determine the methylation pattern of the one or more biomarkers. In some embodiments, said detecting comprises a real-time quantitative probe-based PCR or a digital probe-based PCR. In some embodiments, the digital probe-based PCR is a digital droplet PCR. In some embodiments, the set of probes comprises a set of padlock probes. In some embodiments, step b) comprises detecting the methylation pattern of one or more biomarkers selected from Table 2, Table 13, Table 14, or Table 20. In some embodiments, step b) comprises detecting the methylation pattern of one or more biomarkers selected from

cgl9516279, cg06100368, cg25945732, cgl9155007, cgl7952661, cg04072843, cg01250961, cg08131100, cg03788131, cgl7528648 , cg07784526, cgl 8948743, cg23986470, cg00846300, cg01029638, cg08350814, cg05098590, cgl 8085998, cg06532037, cgl 5313226, cgl6232979, cg26149167, cg01237565, cgl6561543, cgl3771313, cgl3771313, cg08169020, cg08169020, cg21153697, cg07326648, cgl4309384, cg20923716, cg09095222, cg22220310,

cg21950459, cgl3332729, cgl0802543, cg20707333, cgl3169641, cg25352342,

cg09921682, cg02504622, cgl7373759, cg06547203, cg06826710, cg00902147, cgl7609887, cgl 5721142, cg08116711, cg00736681, cgl 8834029, cg06969479, cg24630516, cgl6901821, cg20349803, cg23610994, cgl9313373, cgl6508600, cg24096323, cg24746106, cgl2288267, cgl0430690, cg24408776, cg05630192, cgl2028674, cg24820270, cgl2028674, cg26718707, cgl0349880, cg09921682, cg25934700, cgl4164596, cg24461337, cg23041410, cg07366553, cg26859666, cg06405341, cg08557188, cg00690392, cg03421440, cg07077277, or cg20702527. In some embodiments, the subject is suspected of having a breast cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cgl 9516279, cg06100368, cg20349803, cg23610994, cgl9313373, cgl6508600, and cg24096323. In some embodiments, the subject is determined to have a breast cancer if: at least one of the eg markers cgl9516279 and cg06100368 is hypermethylated; at least one of the eg markers cg20349803, cg23610994, cgl9313373, cgl6508600, and cg24096323 is hypomethylated; or a combination thereof. In some embodiments, the subject is suspected of having a liver cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from

cg25945732, cgl9155007, cgl7952661, cg25934700, cgl4164596, cg24461337, cg23041410, cg07366553, and cg26859666, or cg00456086. In some embodiments, the subject is determined to have a liver cancer if: at least one of the eg markers cg25945732, cgl9155007, or cgl7952661 is hypermethylated; at least one of the eg markers cg25934700, cgl4164596, cg24461337, cg23041410, cg07366553, cg26859666, or cg00456086 is hypomethylated; or a combination thereof. In some embodiments, the subject is suspected of having a liver cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from 3- 49757316, 8-27183116, 8-141607252, 17-29297711, 3-49757306, 19-43979341, 8-141607236,

5- 176829755, 18-13382140, 15-65341965, 3-13152305, 17-29297770, 8-27183316, 5- 176829740, 19-41316693, 18-43830649, 15-65341957, 20-44539531, 7-30265625, 2- 131129567, 5-176829665, 3-13152273, 8-27183348, 3-49757302, 19-41316697, 8-61821442, 20-44539525, 10-102883105, 11-65849129, 5-176829639, 15-91129457, 2-1625431, 6- 151373292, 6-151373294, 20-25027093, 6-14284198, 10-4049295, 19-59023222, 1-184197132, 2-131004117, 2-8995417, 12-10782319, 20-25027033, 6-151373256, 8-86100970, 9-4839459, 17-41221574, 1-153926715, 20-25027044, 20-20177325, 2-1625443, 20-25027085, 11- 69420728, 1-229234865, 6-13408877, 22-50643735, 6-151373308, 1-232119750, 8-134361508, or 6-13408858. In some embodiments, the subject is determined to have a liver cancer if: at least one of the markers 3-49757316, 8-27183116, 8-141607252, 17-29297711, 3-49757306, 19- 43979341, 8-141607236, 5-176829755, 18-13382140, 15-65341965, 3-13152305, 17-29297770, 8-27183316, 5-176829740, 19-41316693, 18-43830649, 15-65341957, 20-44539531, 7- 30265625, 2-131129567, 5-176829665, 3-13152273, 8-27183348, 3-49757302, 19-41316697, 8- 61821442, 20-44539525, 10-102883105, 11-65849129, or 5-176829639 is hypermethylated; at least one of the markers 15-91129457, 2-1625431, 6-151373292, 6-151373294, 20-25027093, 6- 14284198, 10-4049295, 19-59023222, 1-184197132, 2-131004117, 2-8995417, 12-10782319, 20-25027033, 6-151373256, 8-86100970, 9-4839459, 17-41221574, 1-153926715, 20-25027044, 20-20177325, 2-1625443, 20-25027085, 11-69420728, 1-229234865, 6-13408877, 22-50643735,

6- 151373308, 1-232119750, 8-134361508, or 6-13408858 is hypomethylated; or a combination thereof. In some embodiments, the subject is suspected of having an ovarian cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from

cg04072843, cg01250961, cg24746106, cgl2288267, and cgl0430690. In some embodiments, the subject is determined to have an ovarian cancer if: at least one of the eg markers cg04072843 and cg01250961 is hypermethylated; at least one of the eg markers

cg24746106, cgl2288267, and cgl0430690 is hypomethylated; or a combination thereof. In some embodiments, the subject is suspected of having a colorectal cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cg08131100, cg03788131, cgl7528648 , cg07784526, cgl8948743, cg23986470, cg00846300,

cg25352342, cg09921682, cg02504622, cgl7373759, cgl2028674, cg24820270, cgl2028674, cg26718707, cgl0349880, and cg09921682. In some embodiments, the subject is determined to have a colorectal cancer if: at least one of the eg markers cg08131100, cg03788131, cgl7528648, cg07784526, cgl 8948743, cg23986470, or cg00846300 is hypermethylated; at least one of the eg markers cg25352342, cg09921682, cg02504622, cgl7373759, cgl2028674, cg24820270, cgl2028674, cg26718707, cgl0349880, or cg09921682 is hypomethylated; or a combination thereof. In some embodiments, the subject is suspected of having a colorectal cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from

cgl0673833, cgl0493436, cgl0428836, cg27284288, cgl6959747, cgl7494199, cg23678254, cg24067911, or cg25459300. In some embodiments, the subject is suspected of having a colorectal cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cg05205843, cgl l841704, cg06699564, cg08924619, cgl l959316, cg08924619, cg06699564, cg01824933, cg08924619, cg05205842, cg08924619, cg04049981, cg09026722, cg03616722, cg08924619, cg05928904, cg08704934, cg09776772, cgl7494199, cg01824933, cgl6296417, cg09776772, cg09776772, cg05338167, cgl0493436, cgOl 1251410, cgl6391792, cg06393830, cg09366118, cg22513455, cgl7583432, cg23881926, cg09638208, cgl2441066, cg27284288, cg04441857, cgl7583432, cgl0673833, cgl9757176, cg08670281, cgl7583432, cg04460364, cgl6959747, cgl5011734, or cg25754195. In some embodiments, the subject is determined to have a colorectal cancer if: at least one of the eg markers cg06393830, cg09366118, cg22513455, cgl7583432, cg23881926, cg09638208, cgl2441066, cg27284288, _C g04441857, cgl7583432, cgl0673833, cgl9757176, cg08670281, cgl7583432, cg04460364, cgl6959747, cgl5011734, or cg25754195 is hypermethylated; at least one of the eg markers cg05205843, cgl l841704, cg06699564, cg08924619, cgl l959316, cg08924619, cg06699564, cgO 1824933, cg08924619, cg05205842, cg08924619, cg04049981, cg09026722, cg03616722, cg08924619, cg05928904, cg08704934, cg09776772, cgl7494199, cg01824933, cgl6296417, cg09776772, cg09776772, cg05338167, cgl0493436, cgOl 1251410, or cgl6391792 is hypomethylated; or a combination thereof. In some embodiments, the subject is suspected of having a prostate cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cg01029638, cg08350814, cg05098590, cgl8085998, cg06532037, cgl5313226, cgl6232979, cg26149167, cg06547203,

cg06826710, cg00902147, cgl7609887, and cgl5721142. In some embodiments, the subject is determined to have a prostate cancer if: at least one of the eg markers cg01029638, cg08350814, cg05098590, cgl8085998, cg06532037, cgl5313226, cgl6232979, or cg26149167 is

hypermethylated; at least one of the eg markers cg06547203, cg06826710, cg00902147, cgl7609887, or cgl5721142 is hypomethylated; or a combination thereof. In some embodiments, the subject is suspected of having a pancreatic cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cg01237565, cgl6561543, and cg08116711. In some embodiments, the subject is determined to have a pancreatic cancer if: at least one of the eg markers cg01237565 or cgl6561543 is hypermethylated; eg marker cg08116711 is hypomethylated; or a combination thereof. In some embodiments, the subject is suspected of having acute myeloid leukemia and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cgl3771313, cgl3771313, and cg08169020. In some embodiments, the subject is suspected of having cervical cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cg08169020, cg21153697, cg07326648, cgl4309384, cg20923716, cg22220310, cg21950459, cgl3332729, cgl0802543, cg20707333, and cgl3169641. In some embodiments, the subject is determined to have cervical cancer if: at least one of the eg markers cg08169020, cg21153697, cg07326648, cgl4309384, or cg20923716 is hypermethylated; at least one of the eg markers cg22220310, cg21950459, cgl3332729, cgl0802543, cg20707333, or cgl3169641 is hypomethylated; or a combination thereof. In some embodiments, the subject is suspected of having sarcoma and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cg09095222. In some embodiments, the subject is determined to have sarcoma if at least eg marker cg09095222 is hypermethylated. In some embodiments, the subject is suspected of having stomach cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cg00736681 and cgl8834029. In some embodiments, the subject is determined to have stomach cancer if at least one of the eg markers cg00736681 or cgl8834029 is hypomethylated. In some embodiments, the subject is suspected of having thyroid cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cg06969479, cg24630516, and cgl6901821. In some embodiments, the subject is determined to have thyroid cancer if at least one of the eg markers cg06969479, cg24630516, or cgl6901821 is hypomethylated. In some embodiments, the subject is suspected of having mesothelioma and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cg05630192. In some embodiments, the subject is determined to have mesothelioma if eg marker cg05630192 is hypomethylated. In some embodiments, the subject is suspected of having glioblastoma and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cg06405341. In some embodiments, the subject is suspected of having lung cancer and step b) comprises detecting the methylation pattern of one or more biomarkers selected from cg08557188, cg00690392, cg03421440, and cg07077277. In some embodiments, the subject is determined to have lung cancer if at least one of the eg markers cg08557188,

cg00690392, cg03421440, or cg07077277 is hypomethylated. In some embodiments, the biological sample is a blood sample, a urine sample, a saliva sample, a sweat sample, or a tear sample. In some embodiments, the biological sample is a cell-free DNA sample. In some embodiments, the biological sample comprises circulating tumor cells. [0006] In certain embodiments, disclosed herein is a kit comprising a set of nucleic acid probes that hybridizes to target sequences of eg markers illustrated in Table 1, Table 2, Table 7, Table 8, Table 13, Table 14, Table 20, or a combination thereof. In some embodiments, the set of nucleic acid probes hybridizes to target sequences of eg markers selected from Table 1. In some embodiments, the set of nucleic acid probes hybridizes to target sequences of eg markers selected from Table 2. In some embodiments, the set of nucleic acid probes hybridizes to target sequences of eg markers selected from Table 7. In some embodiments, the set of nucleic acid probes hybridizes to target sequences of eg markers selected from Table 8. In some embodiments, the set of nucleic acid probes hybridizes to target sequences of eg markers selected from Table 13. In some embodiments, the set of nucleic acid probes hybridizes to target sequences of eg markers selected from Table 14. In some embodiments, the set of nucleic acid probes hybridizes to target sequences of eg markers selected from Table 20. In some embodiments, the set of nucleic acid probes hybridizes to target sequences of eg markers selected from egl 9516279, cg06100368, cg25945732, cgl9155007, cgl7952661, cg04072843, cg01250961, cg08131100, cg03788131, cgl7528648 , cg07784526, cgl 8948743, cg23986470, cg00846300, cg01029638, cg08350814, cg05098590, cgl 8085998, cg06532037, cgl 5313226, cgl6232979, cg26149167, cg01237565, cgl6561543, cgl3771313, cgl3771313, cg08169020, cg08169020, cg21153697, cg07326648, cgl4309384, cg20923716, cg09095222, cg22220310, cg21950459, cgl3332729, cgl0802543, cg20707333, cgl3169641, cg25352342, cg09921682, cg02504622, cgl7373759, cg06547203, cg06826710, cg00902147, cgl7609887, cgl 5721142, cg08116711, cg00736681, cgl 8834029, cg06969479, cg24630516, cgl6901821, cg20349803, cg23610994, cgl9313373, cgl6508600, cg24096323, cg24746106, cgl2288267, cgl0430690, cg24408776, cg05630192, cgl2028674, cg24820270, cgl2028674, cg26718707, cgl0349880, cg09921682, cg25934700, cgl4164596, cg24461337, cg23041410, cg07366553, cg26859666, cg06405341, cg08557188, cg00690392, cg03421440, cg07077277, cg00456086, and cg20702527. In some embodiments, the set of nucleic acid probes hybridizes to target sequences of cgl0673833, cgl0493436, cgl0428836, cg27284288, cgl6959747, cgl7494199, cg23678254, cg24067911, or cg25459300. In some embodiments, the set of nucleic acid probes hybridizes to target sequences of cgl0673833 or cg25462303. In some embodiments, the set of nucleic acid probes hybridizes to target sequences of cg05205843, cgl l 841704, cg06699564, cg08924619, cgl l959316, cg08924619, cg06699564, cgO 1824933, cg08924619, cg05205842, cg08924619, cg04049981, cg09026722, cg03616722, cg08924619, cg05928904, cg08704934, cg09776772, cgl7494199, cg01824933, cgl6296417, cg09776772, cg09776772, cg05338167, cgl0493436, cgOl 1251410, or cgl6391792. In some embodiments, the set of nucleic acid probes hybridizes to target sequences of cg06393830, cg09366118, cg22513455, cgl7583432, cg23881926, cg09638208, cgl2441066, cg27284288, _C g04441857, cgl7583432, cgl0673833, cgl9757176, cg08670281, cgl7583432, cg04460364, cgl6959747, cgl5011734, or cg25754195. In some embodiments, the set of nucleic acid probes comprises a set of padlock probes.

BRIEF DESCRIPTION OF THE DRAWINGS

[0007] Various aspects of the disclosure are set forth with particularity in the appended claims. The file of this patent contains at least one drawing/photograph executed in color. Copies of this patent with color drawing(s)/photograph(s) will be provided by the Office upon request and payment of the necessary fee. A better understanding of the features and advantages of the present disclosure will be obtained by reference to the following detailed description that sets forth illustrative embodiments, in which the principles of the disclosure are utilized, and the accompanying drawings of which:

[0008] Fig. 1 illustrates the methylation status of biomarker 7-1577016.

[0009] Fig. 2 illustrates the methylation status of biomarker 11-67177103.

[0010] Fig. 3 illustrates the methylation status of biomarker 19-10445516 (cgl7126555).

[0011] Fig. 4 illustrates the methylation status of biomarker 12-122277360.

[0012] Fig. 5 illustrates the methylation status of biomarker 6-72130742 (cg24772267).

[0013] Fig. 6 illustrates the methylation status of biomarker 3-15369681.

[0014] Fig. 7 illustrates the methylation status of biomarker 3-131081177.

[0015] Fig. 8 illustrates workflow chart of data generation and analysis. Whole genome methylation data on HCC and normal lymphocytes were used to identify 401 candidate markers.

Diagnostic marker selection: Lasso and Random-forest analyses were applied to a training cohort of 715 HCC and 560 normal patients to identify a final selection of 10 markers. These ten markers were applied to a validation cohort of 383 HCC and 275 normal patients. Prognostic marker selection: univariant-cox and LASSO-Cox were applied to a training cohort of 680 HCC patients with survival data to identify a final selection of eight markers. These eight markers were applied to a validation cohort of 369 HCC with survival data.

[0016] Fig. 9A-Fig. 9H illustrate cfDNA methylation analysis for diagnosis of HCC. Fig. 9A shows the heatmap of methylation of 28 pairs of matched HCC tumor DNA and plasma cfDNA, with a mean methylation value threshold of 0.1 as a cutoff. Fig. 9B shows the methylation values and standard deviations of ten diagnostic markers in normal plasma, HCC tumor DNA, and HCC patient cfDNA. Fig. 9C and Fig. 9D show the confusion tables of binary results of the diagnostic prediction model in the training (Fig. 9C) and validation datasets (Fig. 9D). Fig. 9E and Fig. 9F illustrate ROC of the diagnostic prediction model with methylation markers in the training (Fig. 9E) and validation datasets (Fig. 9F). Fig. 9G and Fig. 9H show the unsupervised hierarchical clustering of ten methylation markers selected for use in the diagnostic prediction model in the training (Fig. 9G) and validation datasets (Fig. 9H). [0017] Fig. 1 OA-Fig. 10K illustrate cfDNA methylation analysis and tumor burden, treatment response, and staging. The combined diagnosis score (cd-score) (Fig. 10A) and AFP (Fig. 10B) in healthy controls, individuals with liver diseases (HBV/HCV infection, cirrhosis, and fatty liver) and HCC patients. Fig. IOC shows the cd-score in normal controls and HCC patients with and without detectable tumor burden. Fig. 10D shows the cd-score in normal controls, HCC patients before treatment, with treatment response, and with progression. Fig. 10E shows the cd-score in normal controls and HCC patients before surgery, after surgery, and with recurrence. Fig. 10F shows the cd-score in normal controls and HCC patients from stage I-IV. Fig. 10G shows the ROC of cd-score and AFP for HCC diagnosis in whole HCC cohort, cd-score (Fig. 10H) and AFP (Fig. 101) in HCC patients with initial diagnosis (before surgery or other treatment), with treatment response, with progression, and with recurrence, cd-score (Fig. 10 J) and AFP (Fig. 10K) in HCC patients from stage I-TV.

[0018] Fig. 11 A-Fig. 11 G illustrate cfDNA methylation analysis for prognostic prediction HCC survival. Fig. 11 A and Fig. 1 IB show the overall survival curves of HCC patients with low or high risk of death at 6 months, according to the combined prognosis score (cp-score) in the training (Fig. 11 A) and validation datasets (Fig. 11B). Survival curves of HCC patients with stage I/II and stage III/IV in the training (Fig. 11C) and validation datasets (Fig. 1 ID). The ROC for the cp-score, stage, and cp-score combined with stage in the training (Fig. 1 IE) and validation datasets (Fig. 1 IF). Fig. 11G shows the survival curves of HCC patients with combinations of cp- score risk and stage in the whole HCC cohort.

[0019] Fig. 12 illustrates an unsupervised hierarchical clustering of top 1000 methylation markers differentially methylated between HCC tumor DNA and normal blood. Each column represents an individual patient and each row represents a CpG marker.

[0020] Fig. 13 A-Fig. 13B illustrate an exemplary region encompassing two Blocks of

Correlated Methylation (BCM) in cfDNA samples of from HCC and normal controls. Fig. 13 A shows a genomic neighborhood of the BCM displayed within UCSC genome browser (Pearson correlation track showed correlation data by summing r values for a marker within a BCM. Cg marker names below the Pearson correlation graph (cgl4999168, cgl4088196, cg25574765) were methylation markers from TCGA. Gene name and common SNPs were also listed. Fig. 13B shows a not-to-scale representation of a set of analyzed cg markers belonging to two BCMs in this region. Boundaries between blocks are indicated by a black rectangle, whereas red squares indicate correlated methylation (r>0.5) between two nearby markers. Correlation between any two markers is represented by a square at the intersection of (virtual) perpendicular lines originating from these two markers. White color indicates no significant correlation. 10 newly identified methylation markers in the left MCB anchored by marker cgl4999168 or 11 newly identified methylation markers in the right MCB anchored by cgl4088196/cg 25574765 were highly consistent and correlated among HCC ctDNA, normal cfDNA, and HCC tissue DNA. Using markers within the same MCB can significantly enhanced allele calling accuracy. Vertical lines at the bottom of panel b were genomic coordinates of boundaries of two MCBs.

[0021] Fig. 14 illustrates an unsupervised hierarchical clustering of exemplary methylation markers for Stage I-Stage IV HCC tumor.

[0022] Fig. 15 shows methylation values correlated with treatment outcomes in HCC patients with serial plasma samples. Fig. 15A shows a change in cd-score comparing patients after surgery, with clinical response, and with disease progression (*** p<0.00\). Fig. 15B shows cd- score trends in individual patients after complete surgical resection with treatment response, and with disease progression. PRE: pre-treatment; POST: after-treatment.

[0023] Fig. 16 illustrates a dynamic monitoring of treatment outcomes in individual patients with cd-score and AFP. Dates of treatments are indicated by vertical blue arrows. PD, progressive disease; PR partial response; SD, stable disease; TACE, trans-catheter arterial

chemoembolization.

[0024] Fig. 17A-Fig. 17C illustrates data analysis of an exemplary marker cgl0673833.

[0025] Fig. 18 illustrates a workflow for building the diagnostic and prognostic models. Whole genome methylation data on HCC, LUNC and normal blood were used to identify candidate markers for probe design. Left panel: diagnostic marker selection: LASSO analysis was applied to a training cohort of 444 HCC, 299 LUNC, and 1123 normal patients to identify a final selection of 77 markers. These 77 markers were applied to a validation cohort of 445 HCC, 300 LUNC, and 1124 normal patients. Right panel: prognostic marker selection: LASSO-Cox were applied to a training cohort of 433 HCC and 299 LUNC patients with survival data to identify a final selection of 20 markers. These 20 markers were applied to a validation cohort of 434 HCC and 300 LUNC with survival data.

[0026] Fig. 19A-Fig. 19D illustrates cfDNA methylation analysis for diagnosis of LUNC and HCC. Fig. 19A shows receiver operating characteristic (ROC) curves and the associated Area Under Curves (AUCs) of the diagnostic prediction model (cd-score) using cfDNA methylation analysis in the validation cohort. Fig. 19B shows box plot of composite scores used to classify normal and cancer patients (left), and LUNC and HCC patients (right). Unsupervised hierarchical clustering of methylation markers differentially methylated between cancer (HCC and LUNC) and normal (Fig. 19C) and between HCC and LUNC (Fig. 19D). Each row represents an individual patient and each column represents a MCB marker.

[0027] Fig. 20A-Fig. 20D illustrates methylation profiling in healthy control, high-risk patients and cancer patients. Fig. 20A shows methylation profiling differentiates HCC from high risk liver disease patients or normal controls. High risk liver diseases were defined as hepatitis, liver cirrhosis and fatty liver disease. Fig. 20B shows serum AFP differentiates HCC from high risk liver disease patients or normal controls. Fig. 20C shows methylation profiling differentiates LUNC from patients who smoke and normal controls. Fig. 20D shows serum CEA differentiates LUNC from high risk (smoking) patients.

[0028] Fig. 21 A-Fig. 21R illustrates cfDNA methylation analysis could predict tumor burden, staging, and treatment response using a composite diagnosis score in LUNC and HCC patients, cd-score in patients with and without detectable tumor burden in LUNC (Fig. 21 A) when compared to CEA (Fig. 211) and HCC (Fig. 21E) when compared to AFP (Fig. 21M); cd-score of patients with stage I/II and stage III/TV disease in LUNC (Fig. 2 IB) when compared to CEA (Fig. 21 J) and HCC (Fig. 21F) patients when compared to AFP (Fig. 21N); cd-score in patients before intervention, after surgery, and with recurrence in LUNC (Fig. 21C) when compared to CEA (Fig. 21K) and HCC (Fig. 21G) when compared to AFP (Fig. 210); cd-score in patients before intervention, with treatment response, and with worsening progression in LUNC (Fig. 2 ID) when compared to CEA (Fig. 21L) and HCC (Fig. 21H) when compared to AFP (Fig. 21P); Fig. 21Q: The ROC curve and the AUC of cd-score and AFP for LUNC diagnosis in the entire LUNC cohort. Fig. 21R: The ROC curve and the AUC of cd-score and AFP for HCC diagnosis in the entire HCC cohort.

[0029] Fig. 22A-Fig. 22F illustrates prognostic prediction in HCC and LUNC survival based on cfDNA methylation profiling. Fig. 22A shows the overall survival curves of HCC patients with low or high risk of death, according to the combined prognosis score (cp-score) in the validation cohort. Fig. 22B shows the overall survival curves of LUNC patients with low or high risk of death, according to the combined prognosis score (cp-score) in the validation dataset. Fig. 22C shows the survival curves of HCC patients with stage I/II and stage III/TV in the validation cohort. Fig. 22D shows the survival curves of patients with stage Ι/Π and stage HI/TV LUNC in the validation cohort. The ROC for 12 months survival predicted by cp-score, CEA, AFP, stage, and cp-score combined with stage of HCC (Fig. 22E) and LUNC (Fig. 22F) in the validation cohort.

[0030] Fig. 23 A-Fig. 23B illustrates early detection of LUNC using a cfDNA methylation panel. 208 smoker patients was enrolled with lung nodules betweenlO mm and 30 mm in size in a prospective trial and measured a cfDNA LUNC methylation panel. Patients were divided into a training and a testing cohort (Fig. 23 A); Receiver operating characteristic (ROC) curves and the associated Area Under Curves (AUCs) of the prediction of Stage I LUNC versus benign lung nodules in the validation cohort with 91.4% accuracy (Fig. 23B); table showing prediction results between Stage I LUNC versus benign lung nodules showing high sensitivity and specificity in the validation cohort.

[0031] Fig. 24A-Fig. 24D illustrates methylation markers can differentiate between HCC and liver cirrhosis and Detect progression from liver cirrhosis to HCC. A prediction model was first built using 217 HCC and 241 cirrhosis patients and divided patients into a training and a testing cohort (Fig. 24A); Receiver operating characteristic (ROC) curves and the associated Area Under Curves (AUCs) of the prediction of Stage I HCC versus liver cirrhosis in the validation cohort with 89.9% accuracy (Fig. 24B); table showing prediction results between Stage I HCC and liver cirrhosis in a validation cohort (Fig. 24C); table showing prediction results on progression from liver cirrhosis to stage 1HCC with high sensitivity (89.5%) and specificity (98%) (Fig. 24D).

[0032] Fig. 25 A illustrates unsupervised hierarchical clustering of top 1000 methylation markers differentially methylated in DNA in HCC and LUNC primary tissues versus normal blood.

[0033] Fig. 25B shows unsupervised hierarchical clustering of the top 1000 methylation markers differentially methylated between HCC and LUNC tissue DNA. Each column represents an individual patient and each row represents a CpG marker.

[0034] Fig. 25C shows global view of supervised hierarchical clustering of all 888 MCBs in the entire cfDNA dataset.

[0035] Fig. 26 illustrates Boxplots showing the features of MCBs in cohorts. Top plot: Mean values and deviations of Lasso MCBs in each one versus rest comparison.

[0036] Fig. 27 illustrates methylation values correlated with treatment outcomes in HCC and LUNC patients with serial plasma samples. Summary graphs of change in methylation value comparing patients after surgery, with clinical response (Partial Remission (PR) or Stable Disease (SD), or with disease progression/recurrent (PD).

[0037] Fig. 28A shows dynamic monitoring of treatment outcomes using the total methylation copy numbers of an MCB in LUNC patients.

[0038] Fig. 28B shows dynamic monitoring of treatment outcomes with the methylation value of an MCB in LUNC patients. PD, progressive disease; PR partial response; SD, stable disease; chemo, chemotherapy.

[0039] Fig. 29 illustrates dynamic monitoring of treatment outcomes using the total methylation copy numbers of an MCB and CEA in HCC patients.

[0040] Fig. 30 shows dynamic monitoring of treatment outcomes with the methylation rate of an MCB in HCC patients. Dates of treatments are indicated in the figure. PD, progressive disease; PR partial response; SD, stable disease; chemo, chemotherapy, TACE, trans-catheter arterial chemoembolization.

[0041] Fig. 31 A-Fig. 3 IB illustrate workflow chart described in Example 5. Fig. 31 A illustrates an exemplary workflow for building the diagnostic model, prognostic model, and generating the subtype based ctDNA methylation. Fig. 3 IB shows the enrollment and outcomes of the prospective screening cohort study. [0042] Fig. 32A-Fig. 32H illustrate cfDNA methylation analysis for diagnosis of CRC. Fig. 32A: exemplary workflow for building the diagnostic models. Fig. 32B: Unsupervised hierarchical clustering of methylation markers differentially methylated between cancer (CRC) and normal in the training and the validation (Fig. 32C) testing cohort. Each row represents an individual patient and each column represents a CpG marker. Fig. 32D: Receiver operating characteristic (ROC) curves and the associated Area Under Curves (AUCs) of the diagnostic prediction model (cd-score) using cfDNA methylation analysis in the training and the validation (Fig. 32E) testing cohort. Fig. 32F: ROC curves and corresponding Area Under the Curve (AUCs) of cd-score and CEA for CRC diagnosis. Fig. 32G: Confusion matrices built from diagnostic model prediction in the training and the validation (H) testing cohort.

[0043] Fig. 33A-Fig. 33E illustrate prognostic prediction in CRC survival based on cfDNA methylation profiling. Fig. 33A: an exemplary workflow for building the prognostic models. Fig. 33B: Overall survival curves of CRC patients with low or high risk of death, according to the combined prognosis score (cp-score) in the training testing cohort. Fig. 33C: Overall survival curves of HCC patients with low or high risk of death, according to the combined prognosis score (cp-score) in the validation testing cohort. The ROC and corresponding AUCs for 12 months survival predicted by cp-score, Primary tumor location, TNM stage, CEA status and combined all in the training (Fig. 33D) and validation (Fig. 33E) testing cohort.

[0044] Fig. 34A illustrates a nomogram for predicting one year overall survival of CRC patients using cp-score and other clinical factors.

[0045] Fig. 34B illustrates a calibration plot of nomogram in external validation.

[0046] Fig. 35A-Fig. 35E cfDNA methylation subtyping analysis in 801 patients with CRC. Fig. 35 A: A schematic diagram shown that the core algorithm utilized in the sample clustering. Fig. 35B: Iteratively unsupervised clustering of cfDNA methylation markers identified two subtypes/clusters in training data. Clinical and molecular features are indicated by the annotation bars above the heatmap. Patients without such information were colored in white. Mutation status was defined by the mutation detected in one of the following genes: BRAF, KRAS, NRAS and PIK3CA. Fig. 35C: Silhouette analysis of the clusters in the last iteration. Fig. 35D: Predicted subtypes/clusters of validation using the 45 makers. Fig. 35E: upper panel: overall survival for each of the cfDNA methylation in each subtypes, (log rank test p<0.05). lower panel: proportion of III-IV stage CRC patients in two subtypes (Chi-squared test, **P<0.01, *P<0.05. left, training cohort; right, validation cohort).

[0047] Fig. 36A-Fig. 36B presents a list of Methylation Correlated Blocks (MCBs) used for cd-score generation. Fig. 36A: MCBs markers selected by muti-class LASSO. Fig. 36B:

Diagnostic marker selection: LASSO-based feature selection identified 13 markers and Random Forest-based feature selection identified 22 markers for discriminating cancer versus normal. There were 9 overlapping markers between these two methods.

[0048] Fig. 37A-Fig. 37F show cfDNA methylation analysis could predict tumor burden, staging, and treatment response using a cd-score in CRC patients. Fig. 37A: cfDNA methylation analysis cd-score in patients with and without detectable tumor burden; Fig. 37B: cd-score of patients with stage I/II and stage III/TV disease; Fig. 37C: cd-score in patients with primary tumor location on left or on right; Fig. 37D: CEA in patients with stage I/II and stage III/TV CRC; Fig. 37E: cd-score in patients before treatment, after surgery ,and with tumor recurrence; Fig. 37F: CEA in CRC patients before treatment, after surgery ,and with tumor recurrence; Recurrence was defined as tumor initially disappeared after treatment/surgery but recurred after a defined period.

[0049] Fig. 38A-Fig. 38C illustrate comparison of subtype markers, diagnosis markers and prognosis markers. Fig. 38A: Venn diagram shows the intersects of the three marker lists.

Patients in cluster 2 had higher cpscores than those in cluster 1 from the both training cohort (Fig. 38B) and validation cohort (Fig. 38C).

[0050] Fig. 39 illustrates patient treatment monitoring with marker methylation level. Dynamic monitoring of treatment outcomes with the methylation value of CpG site cgl0673833 (upper panel) and CEA (lower panel) in CRC patients #1-6. Dates of treatments are indicated in the figure. PD, progressive disease; PR partial response; SD, stable disease; chemo, chemotherapy.

[0051] Fig. 40A-Fig. 40B illustrates methylation values correlated with treatment outcomes in CRC patients with serial plasma samples. Fig. 40A: Summary graphs of change in methylation value comparing patients after surgery, with clinical response (Partial Remission (PR) or Stable Disease (SD), or with disease progression/recurrent (PD). Fig. 40B: Methylation value trends in individual patients after complete surgical resection, with treatment response, and with disease progression. Delta methylation rate denotes the methylation value difference before treatment and after treatment. PRE: pre-treatment; POST: after-treatment.

[0052] Fig. 41 illustrates the methylation status of CpG marker cg00456086.

[0053] Fig. 42 illustrates the methylation status of biomarker 3-49757316, 8-27183116, 8- 141607252, 17-29297711, and 3-49757306.

[0054] Fig. 43 illustrates the methylation status of biomarker 19-43979341, 8-141607236, 5- 176829755, 18-13382140, and 15-65341965.

[0055] Fig. 44 illustrates the methylation status of biomarker 15-91129457, 2-1625431, 6- 151373292, 6-151373294, and 20-25027093.

[0056] Fig. 45 illustrates the methylation status of biomarker 6-14284198, 10-4049295, 19- 59023222, 1-184197132, and 2-131004117.

[0057] Fig. 46 illustrates the methylation status of biomarker 3-13152305, 17-29297770, 8- 27183316, 5-176829740, and 19-41316693. [0058] Fig. 47 illustrates the methylation status of biomarker 18-43830649, 15-65341957, 20- 44539531, 7-30265625, and 2-131129567.

[0059] Fig. 48 illustrates the methylation status of biomarker 2-8995417, 12-10782319, 20- 25027033, 6-151373256, and 8-86100970.

[0060] Fig. 49 illustrates the methylation status of biomarker 9-4839459, 17-41221574, 1- 153926715, 20-25027044, and 20-20177325.

[0061] Fig. 50 illustrates the methylation status of biomarker 176829665, 3-13152273, 8- 27183348, 3-49757302, and 19-41316697.

[0062] Fig. 51 illustrates the methylation status of biomarker 8-61821442, 20-44539525, 10- 102883105, 11-65849129, and 5-176829639.

[0063] Fig. 52 illustrates the methylation status of biomarker 2-1625443, 20-25027085, 11- 69420728, 1-229234865, and 6-13408877.

[0064] Fig. 53 illustrates the methylation status of biomarker 22-50643735, 6-151373308, 1- 232119750, 8-134361508, and 6-13408858.

DETAILED DESCRIPTION OF THE DISCLOSURE

[0065] Cancer is characterized by an abnormal growth of a cell caused by one or more mutations or modifications of a gene leading to dysregulated balance of cell proliferation and cell death. DNA methylation silences expression of tumor suppression genes, and presents itself as one of the first neoplastic changes. Methylation patterns found in neoplastic tissue and plasma demonstrate homogeneity, and in some instances are utilized as a sensitive diagnostic marker. For example, cMethDNA assay has been shown in one study to be about 91% sensitive and about 96% specific when used to diagnose metastatic breast cancer. In another study, circulating tumor DNA (ctDNA) was about 87.2% sensitive and about 99.2% specific when it was used to identify KRAS gene mutation in a large cohort of patients with metastatic colon cancer (Bettegowda et al, Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies. Sci. Transl. Med, 6(224):ra24. 2014). The same study further demonstrated that ctDNA is detectable in >75% of patients with advanced pancreatic, ovarian, colorectal, bladder, gastroesophageal, breast, melanoma, hepatocellular, and head and neck cancers (Bettegowda et al).

[0066] Additional studies have demonstrated that CpG methylation pattern correlates with neoplastic progression. For example, in one study of breast cancer methylation patterns, PI 6 hypermethylation has been found to correlate with early stage breast cancer, while TIMP3 promoter hypermethylation has been correlated with late stage breast cancer. In addition, BMP6, CST6 and TIMP3 promoter hypermethylation have been shown to associate with metastasis into lymph nodes in breast cancer. [0067] In some embodiments, DNA methylation profiling provides higher clinical sensitivity and dynamic range compared to somatic mutation analysis for cancer detection. In other instances, altered DNA methylation signature has been shown to correlate with the prognosis of treatment response for certain cancers. For example, one study illustrated that in a group of patients with advanced rectal cancer, ten differentially methylated regions were used to predict patients' prognosis. Likewise, RASSF1 A DNA methylation measurement in serum was used to predict a poor outcome in patients undergoing adjuvant therapy in breast cancer patients in a different study. In addition, SRBC gene hypermethylation was associated with poor outcome in patients with colorectal cancer treated with oxaliplatin in a different study. Another study has demonstrated that ESR1 gene methylation correlates with clinical response in breast cancer patients receiving tamoxifen. Additionally, ARFII gene promoter hypermethylation was shown to be a predictor of long-term survival in breast cancer patients not treated with tamoxifen.

[0068] In some embodiments, disclosed herein include methods, probes, and kits for diagnosing the presence of cancer and/or a cancer type. In some instances, described herein is a method of profiling the methylation status of a set of CpG markers (or eg markers). In other instances, described herein is a method for selecting a patient based on the methylation status of a set of CpG markers (or eg markers) for treatment.

Methods of Use

[0069] DNA methylation is the attachment of a methyl group at the C5 -position of the nucleotide base cytosine and the N6-position of adenine. Methylation of adenine primarily occurs in prokaryotes, while methylation of cytosine occurs in both prokaryotes and eukaryotes. In some instances, methylation of cytosine occurs in the CpG dinucleotides motif. In other instances, cytosine methylation occurs in, for example CHG and CHH motifs, where H is adenine, cytosine or thymine. In some instances, one or more CpG dinucleotide motif or CpG site forms a CpG island, a short DNA sequence rich in CpG dinucleotide. In some instances, a CpG island is present in the 5' region of about one half of all human genes. CpG islands are typically, but not always, between about 0.2 to about 1 kb in length. Cytosine methylation further comprises 5 -methyl cytosine (5-mCyt) and 5-hydroxymethylcytosine.

[0070] The CpG (cytosine-phosphate-guanine) or CG motif refers to regions of a DNA molecule where a cytosine nucleotide occurs next to a guanine nucleotide in the linear strand. In some instances, a cytosine in a CpG dinucleotide is methylated to form 5 -methyl cytosine. In some instances, a cytosine in a CpG dinucleotide is methylated to form 5-hydroxymethylcytosine.

[0071] In some instances, one or more DNA regions are hypermethylated. In such cases, hypermethylation refers to an increase in methylation event of a region relative to a reference region. In some cases, hypermethylation is observed in one or more cancer types, and is useful, for example, as a diagnostic marker and/or a prognostic marker.

[0072] In some instances, one or more DNA regions are hypomethylated. In some cases, hypomethylation refers to a loss of the methyl group in the 5 -methyl cytosine nucleotide in a first region relative to a reference region. In some cases, hypomethylation is observed in one or cancer types, and is useful, for example, as a diagnostic marker and/or a prognostic marker.

[0073] In some embodiments, disclosed herein are CpG methylation markers for diagnosis of a cancer in a subject. In some instances, also disclosed herein is a method of selecting a subject suspected of having cancer for treatment. In some instances, the method comprises (a) contacting treated DNA with at least one probe from a probe panel to generate an amplified product, wherein the at least one probe hybridizes under high stringency condition to a target sequence of a eg marker selected from Table 1, Table 2, Table 7, Table 8, or Table 13, and wherein the treated DNA is processed from a biological sample obtained from the subject; (b) analyzing the amplified product to generate a methylation profile of the eg marker; (c) comparing the methylation profile to a reference model relating methylation profiles of eg markers from Tables 1, 2, 7, 8, and 13 to a set of cancers; (d) based on the comparison of step c), determining: (i) whether the subject has cancer; and (ii) which cancer type the subject has; and (e) administering an effective amount of a therapeutic agent to the subject if the subject is determined to have cancer and the cancer type is determined.

[0074] In some instances, the method comprises (a) contacting treated DNA with the probe panel to generate amplified products, wherein each probe of the probe panel hybridizes under high stringency condition to a target sequence of a eg marker selected from Table 1 , Table 2, Table 7, or Table 8; (b) analyzing the amplified products to generate a methylation profile of the eg markers targeted by the probe panel; (c) comparing the methylation profile to the reference model relating methylation profiles of eg markers from Tables 1, 2, 7, and 8 to a set of cancers; (d) evaluating an output from the model to determine: (i) whether the subject has cancer; and (ii) which cancer type the subject has; and (e) administering an effective amount of a therapeutic agent to the subject if the subject is determined to have cancer and the cancer type is determined.

[0075] In some cases, the biological sample is treated with a deaminating agent to generate the treated DNA.

[0076] In some cases, the at least one probe from the probe panel is a padlock probe.

[0077] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 1.

[0078] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 2. [0079] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 4.

[0080] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 5.

[0081] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 7.

[0082] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 8.

[0083] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 13.

[0084] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cgl9516279, cg06100368, cg25945732, cgl9155007, cgl7952661, cg04072843, cg01250961, cg08131100, cg03788131, cgl7528648, cg07784526, cgl 8948743, cg23986470, cg00846300, cg01029638, cg08350814, cg05098590, cgl 8085998, cg06532037, cgl 5313226, cgl6232979, cg26149167, cg01237565, cgl6561543, cgl3771313, cgl3771313, cg08169020, cg08169020, cg21153697, cg07326648, cgl4309384, cg20923716, cg09095222, cg22220310, cg21950459, cgl3332729, cgl0802543, cg20707333, cgl3169641, cg25352342, cg09921682, cg02504622, cgl7373759, cg06547203, cg06826710, cg00902147, cgl7609887, cgl 5721142, cg08116711, cg00736681, cgl 8834029, cg06969479, cg24630516, cgl6901821, cg20349803, cg23610994, cgl9313373, cgl6508600, cg24096323, cg24746106, cgl2288267, cgl0430690, cg24408776, cg05630192, cgl2028674, cg24820270, cgl2028674, cg26718707, cgl0349880, cg09921682, cg25934700, cgl4164596, cg24461337, cg23041410, cg07366553, cg26859666, cg06405341, cg08557188, cg00690392, cg03421440, cg07077277, cg00456086, or cg20702527. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from egl 9516279, cg06100368, cg20349803, cg23610994, cgl9313373, cgl6508600, or cg24096323. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg25945732, cgl9155007, cgl7952661, cg25934700, cgl4164596, cg24461337, cg23041410, cg07366553, cg26859666, or cg00456086. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg04072843, cg01250961, cg24746106, cgl2288267, or cgl0430690. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg08131100, cg03788131, cgl7528648 , cg07784526, cgl 8948743, cg23986470, cg00846300, cg25352342, cg09921682, cg02504622, cgl7373759, cgl2028674, cg24820270, cgl2028674, cg26718707, cgl0349880, or cg09921682. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg01029638, cg08350814, cg05098590, cgl 8085998, cg06532037, cgl 5313226, cgl6232979, cg26149167, cg06547203, cg06826710, cg00902147, cgl7609887, or cgl 5721142. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg01237565, cgl6561543, or cg08116711. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cgl3771313, cgl3771313, or cg08169020. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg08169020, cg21153697, cg07326648, cgl4309384, cg20923716, cg22220310, cg21950459, cgl3332729, cgl0802543, cg20707333, or cgl3169641. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker cg09095222. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg00736681 or cgl 8834029. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg06969479, cg24630516, or egl 6901821. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker cg24408776. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker cg05630192. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker cg06405341. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg08557188, cg00690392, cg03421440, or cg07077277. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cgl0673833,

cgl0493436, cgl0428836, cg27284288, cgl6959747, cgl7494199, cg23678254, cg24067911, or cg25459300.

[0085] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a gene selected from a gene panel consisting of BMPRIA, PSD, ARHGAP25, KLF3, PLAC8, ATXN1, Chromosome 6: 170, Chromosome 6:3, ATAD2, and Chromosome 8:20.

[0086] some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a gene selected from a gene panel consisting of MYOIG, ADAMTS4,

BMPRIA, CD6, RBP5, Chr 13 : 10, LGAP5, ATXN1, and Chr 8:20.

[0087] In some instances, the reference model comprises methylation profiles of eg markers from Tables 1 and 2 generated from samples of known cancer types. In some cases, the reference model further comprises methylation profiles of eg markers from Tables 1 and 2 generated from normal samples. In some cases, the reference model comprises methylation profiles of eg markers from Tables 1 and 2 generated from tissue samples. [0088] In some instances, the reference model comprises methylation profiles of eg markers from Tables 7 and 8 generated from samples of known cancer types. In some cases, the reference model further comprises methylation profiles of eg markers from Tables 7 and 8 generated from normal samples. In some cases, the reference model comprises methylation profiles of eg markers from Tables 7 and 8 generated from tissue samples.

[0089] In some instances, the reference model comprises methylation profiles of eg markers from Table 13 generated from samples of known cancer types. In some cases, the reference model further comprises methylation profiles of eg markers from Table 13 generated from normal samples. In some cases, the reference model comprises methylation profiles of eg markers from Table 13 generated from tissue samples.

[0090] In some cases, the reference model is developed using an algorithm selected from one or more of the following: a principal component analysis, a logistic regression analysis, a nearest neighbor analysis, a support vector machine, and a neural network model.

[0091] In some embodiments, the analyzing described above comprises quantitatively detecting the methylation status of the amplified product. In some cases, the detection comprises a real-time quantitative probe-based PCR or a digital probe-based PCR. In some cases, the detection comprises a real-time quantitative probe-based PCR. In other cases, the detection comprises a digital probe-based PCR, optionally, a digital droplet PCR.

[0092] In some embodiments, the treatment comprises a chemotherapeutic agent or an agent for a targeted therapy. Exemplary chemotherapeutic agents include, but are not limited to, cisplatin, doxorubicin, fluoropyrimidine, gemcitabine, irinotecan, mitoxantrone, oxaliplatin, thalidomide, or a combination thereof. In some cases, the chemotherapeutic agent comprises cisplatin, doxorubicin, fluoropyrimidine, gemcitabine, irinotecan, mitoxantrone, oxaliplatin, thalidomide, or a combination thereof. In some instances, the treatment comprises an agent for a targeted therapy. In additional instances, the treatment comprises surgery.

[0093] In some instances, the biological sample is a blood sample, an urine sample, a saliva sample, a sweat sample, or a tear sample. In some cases, the biological sample is a blood sample or an urine sample. In some cases, the biological sample is a tissue biopsy sample. In some cases, the biological sample is a cell-free DNA sample. In some cases, the biological sample comprises circulating tumor cells.

[0094] In some embodiments, also disclosed herein is a method of detecting the methylation status of a set of eg markers. In some embodiments, the method comprises (a) processing a biological sample obtained from a subject with a deaminating agent to generate treated DNA comprising deaminated nucleotides; (b) contacting the treated DNA with at least one probe that hybridizes under high stringency condition to a target sequence of a eg marker from Table 1, Table 2, Table 7, Table 8, Table 13, Table 14, or Table 20; and (c) quantitatively detecting the methylation status of the eg marker, wherein said detection comprises a real-time quantitative probe-based PCR or a digital probe-based PCR.

[0095] In some embodiments, the method of detecting the methylation status of a set of eg markers comprises(a) processing a biological sample obtained from a subject with a deaminating agent to generate treated DNA comprising deaminated nucleotides; (b) contacting the treated DNA with at least one probe that hybridizes under high stringency condition to a target sequence of a eg marker from Table 1 or Table 2; and (c) quantitatively detecting the methylation status of the eg marker, wherein said detection comprises a real-time quantitative probe-based PCR or a digital probe-based PCR.

[0096] In some cases, the detection comprises a real-time quantitative probe-based PCR or a digital probe-based PCR. In some cases, the detection comprises a real-time quantitative probe- based PCR. In other cases, the detection comprises a digital probe-based PCR, optionally, a digital droplet PCR.

[0097] In some cases, the at least one probe from the probe panel is a padlock probe.

[0098] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 1.

[0099] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 2.

[0100] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 4.

[0101] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 5.

[0102] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 7.

[0103] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 8.

[0104] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 13.

[0105] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 14.

[0106] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from Table 20.

[0107] In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cgl9516279, cg06100368, cg25945732, cgl9155007, cgl7952661, cg04072843, cg01250961, cg08131100, cg03788131, cgl7528648, cg07784526, cgl 8948743, cg23986470, cg00846300, cg01029638, cg08350814, cg05098590, cgl8085998, cg06532037, cgl5313226, cgl6232979, cg26149167, cg01237565, cgl6561543, cgl3771313, cgl3771313, cg08169020, cg08169020, cg21153697, cg07326648, cgl4309384, cg20923716, cg09095222, cg22220310, cg21950459, cgl3332729, cgl0802543, cg20707333, cgl3169641, cg25352342, cg09921682, cg02504622, cgl7373759, cg06547203, cg06826710, cg00902147, cgl7609887, cgl5721142, cg08116711, cg00736681, cgl8834029, cg06969479, cg24630516, cgl6901821, cg20349803, cg23610994, cgl9313373, cgl6508600, cg24096323, cg24746106, cgl2288267, cgl0430690, cg24408776, cg05630192, cgl2028674, cg24820270, cgl2028674, cg26718707, cgl0349880, cg09921682, cg25934700, cgl4164596, cg24461337, cg23041410, cg07366553, cg26859666, cg06405341, cg08557188, cg00690392, cg03421440, cg07077277, cg00456086, or cg20702527. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cgl 9516279, cg06100368, cg20349803, cg23610994, cgl9313373, cgl6508600, or cg24096323. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg25945732, cgl9155007, cgl7952661, cg25934700, cgl4164596, cg24461337, cg23041410, cg07366553, cg26859666, or cg00456086. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg04072843, cg01250961, cg24746106, cgl2288267, or cgl0430690. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg08131100, cg03788131, cgl7528648 , cg07784526, cgl8948743, cg23986470, cg00846300, cg25352342, cg09921682, cg02504622, cgl7373759, cgl2028674, cg24820270, cgl2028674, cg26718707, cgl0349880, or cg09921682. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg01029638, cg08350814, cg05098590, cgl8085998, cg06532037, cgl5313226, cgl6232979, cg26149167, cg06547203, cg06826710, cg00902147, cgl7609887, or cgl5721142. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg01237565, cgl6561543, or cg08116711. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cgl3771313, cgl3771313, or cg08169020. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg08169020, cg21153697, cg07326648, cgl4309384, cg20923716, cg22220310, cg21950459, cgl3332729, cgl0802543, cg20707333, or cgl3169641. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker cg09095222. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg00736681 or cgl8834029. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg06969479, cg24630516, or cgl 6901821. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker cg24408776. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker cg05630192. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker cg06405341. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg08557188, cg00690392, cg03421440, or cg07077277. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cgl0673833,

cgl0493436, cgl0428836, cg27284288, cgl6959747, cgl7494199, cg23678254, cg24067911, or cg25459300. In some instances, the at least one probe hybridizes under high stringency conditions to a target sequence of a eg marker selected from cg05205843, egl 1841704, cg06699564, cg08924619, cgl l959316, cg08924619, cg06699564, cg01824933, cg08924619, cg05205842, cg08924619, cg04049981, cg09026722, cg03616722, cg08924619, cg05928904, cg08704934, cg09776772, cgl7494199, cg01824933, cgl6296417, cg09776772, cg09776772, cg05338167, cgl0493436, cgOl 1251410, cgl6391792, cg06393830, cg09366118, cg22513455, cgl7583432, cg23881926, cg09638208, cgl2441066, cg27284288, cg04441857, cgl7583432, cgl0673833, cgl9757176, cg08670281, cgl7583432, cg04460364, cgl6959747, cgl 5011734, or cg25754195.

[0108] In some embodiments, the methylation status or pattern of a set of eg markers is further used to determine whether the subject has a cancer. For example, the methylation status or pattern of at least one eg marker selected from cgl9516279, cg06100368, cg20349803, cg23610994, cgl9313373, cgl6508600, and cg24096323 is used to determine whether the subject has a breast cancer. In some cases, the subject is determined to have a breast cancer if at least one of the eg markers egl 9516279 and cg06100368 is hypermethylated. In other cases, the subject is determined to have a breast cancer if at least one of the eg markers cg20349803, cg23610994, cgl9313373, cgl6508600, and cg24096323 is hypomethylated.

[0109] In some instances, the methylation status or pattern of at least one eg marker selected from cg25945732, cgl9155007, cgl7952661, cg25934700, cgl4164596, cg24461337, cg23041410, cg07366553, cg00456086, and cg26859666 is used to determine whether the subject has a liver cancer. In some cases, the subject is determined to have a liver cancer if at least one of the eg markers cg25945732, cgl9155007, or cgl7952661 is hypermethylated. In other cases, the subject is determined to have a liver cancer if at least one of the eg markers cg25934700, cgl4164596, cg24461337, cg23041410, cg07366553, cg26859666, or cg00456086 is hypomethylated.

[0110] In some instances, the methylation status or pattern of at least one marker selected from 3-49757316, 8-27183116, 8-141607252, 17-29297711, 3-49757306, 19-43979341, 8-141607236, 5- 176829755, 18-13382140, 15-65341965, 3-13152305, 17-29297770, 8-27183316, 5-

176829740. 19- 41316693, 18-43830649, 15-65341957, 20-44539531, 7-30265625, 2- 131129567, 5-176829665, 3-13152273, 8-27183348, 3-49757302, 19-41316697, 8-61821442, 20-44539525, 10-102883105, 11-65849129, 5-176829639, 15-91129457, 2-1625431, 6- 151373292, 6-151373294, 20-25027093, 6-14284198, 10-4049295, 19-59023222, 1-184197132,

2- 131004117, 2-8995417, 12-10782319, 20-25027033, 6-151373256, 8-86100970, 9-4839459,

17- 41221574, 1-153926715, 20-25027044, 20-20177325, 2-1625443, 20-25027085, 11- 69420728, 1-229234865, 6-13408877, 22-50643735, 6-151373308, 1-232119750, 8-134361508, or 6-13408858 is used to determine whether the subject has a liver cancer. In some instances, the subject is determined to have a liver cancer if at least one of the markers 3-49757316, 8- 27183116, 8-141607252, 17-29297711, 3-49757306, 19-43979341, 8-141607236, 5-176829755,

18- 13382140, 15-65341965, 3-13152305, 17-29297770, 8-27183316, 5-176829740, 19- 41316693, 18-43830649, 15-65341957, 20-44539531, 7-30265625, 2-131129567, 5-176829665,

3- 13152273, 8-27183348, 3-49757302, 19-41316697, 8-61821442, 20-44539525, 10-102883105, 11-65849129, or 5-176829639 is hypermethylated. In some cases, the subject is determined to have a liver cancer if at least one of the markers 15-91129457, 2-1625431, 6-151373292, 6-

151373294. 20- 25027093, 6-14284198, 10-4049295, 19-59023222, 1-184197132, 2-131004117, 2-8995417, 12-10782319, 20-25027033, 6-151373256, 8-86100970, 9-4839459, 17-41221574, 1 - 153926715, 20-25027044, 20-20177325, 2-1625443, 20-25027085, 11-69420728, 1-229234865,

6- 13408877, 22-50643735, 6-151373308, 1-232119750, 8-134361508, or 6-13408858 is hypomethylated.

[0111] In some instances, the methylation status or pattern of at least one eg marker selected from cg04072843, cg01250961, cg24746106, cgl2288267, and cgl0430690 is used to determine whether the subject has an ovarian cancer. In some cases, the subject is determined to have an ovarian cancer if at least one of the eg markers cg04072843 and cg01250961 is hypermethylated. In other cases, the subject is determined to have an ovarian cancer if at least one of the eg markers cg24746106, cgl2288267, and cgl0430690 is hypomethylated.

[0112] In some instances, the methylation status or pattern of at least one eg marker selected from cg08131100, cg03788131, cgl7528648, cg07784526, cgl 8948743, cg23986470, cg00846300, cg25352342, cg09921682, cg02504622, cgl7373759, cgl2028674, cg24820270, cgl2028674, cg26718707, cgl0349880, and cg09921682 is used to determine whether the subject has a colorectal cancer. In some cases, the subject is determined to have a colorectal cancer if at least one of the eg markers cg08131100, cg03788131, cgl7528648, cg07784526, egl 8948743, cg23986470, or cg00846300 is hypermethylated. In other cases, the subject is determined to have a colorectal cancer if at least one of the eg markers cg25352342, cg09921682, cg02504622, cgl7373759, cgl2028674, cg24820270, cgl2028674, cg26718707, cgl0349880, or cg09921682 is hypomethylated.

[0113] In some instances, the methylation status or pattern of at least one eg marker selected from cgl0673833, cgl0493436, cgl0428836, cg27284288, cgl6959747, cgl7494199, cg23678254, cg24067911, or cg25459300 is used to determine whether the subject has a colorectal cancer.

[0114] In some instances, the methylation status or pattern of at least one eg marker selected from cg05205843, cgl l 841704, cg06699564, cg08924619, cgl l959316, cg08924619, cg06699564, cg01824933, cg08924619, cg05205842, cg08924619, cg04049981, cg09026722, cg03616722, cg08924619, cg05928904, cg08704934, cg09776772, cgl7494199, cg01824933, cgl6296417, cg09776772, cg09776772, cg05338167, cgl0493436, cgOl 1251410, cgl6391792, cg06393830, cg09366118, cg22513455, cgl7583432, cg23881926, cg09638208, cgl2441066, cg27284288, cg04441857, cgl7583432, cgl0673833, cgl9757176, cg08670281, cgl7583432, cg04460364, cgl6959747, cgl 5011734, or cg25754195 is used to determine whether the subject has a colorectal cancer. In some cases, the subject is determined to have a colorectal cancer if at least one of the eg markers cg06393830, cg09366118, cg22513455, cgl7583432, cg23881926, cg09638208, cgl2441066, cg27284288, cg04441857, cgl7583432, cgl0673833, cgl9757176, cg08670281, cgl7583432, cg04460364, cgl6959747, cgl 5011734, or cg25754195 is hypermethylated. In other cases, the subject is determined to have a colorectal cancer if at least one of the eg markers cg05205843, cgl l 841704, cg06699564, cg08924619, cgl l959316, cg08924619, cg06699564, cg01824933, cg08924619, cg05205842, cg08924619, cg04049981, cg09026722, cg03616722, cg08924619, cg05928904, cg08704934, cg09776772, cgl7494199, cg01824933, cgl6296417, cg09776772, cg09776772, cg05338167, cgl0493436, cgOl 1251410, or cgl6391792 is hypomethylated.

[0115] In some instances, the methylation status or pattern of at least one eg marker selected from cg01029638, cg08350814, cg05098590, cgl 8085998, cg06532037, cgl 5313226, cgl6232979, cg26149167, cg06547203, cg06826710, cg00902147, cgl7609887, and cgl 5721142 is used to determine whether the subject has a prostate cancer. In some cases, the subject is determined to have a prostate cancer if at least one of the eg markers cgO 1029638, cg08350814, cg05098590, cgl 8085998, cg06532037, cgl 5313226, cgl6232979, or cg26149167 is hypermethylated. In other cases, the subject is determined to have a prostate cancer if at least one of the eg markers cg06547203, cg06826710, cg00902147, cgl7609887, or cgl 5721142 is hypomethylated.

[0116] In some instances, the methylation status or pattern of at least one eg marker selected from cg01237565, cgl6561543, and cg08116711 is used to determine whether the subject has a pancreatic cancer. In some cases, the subject is determined to have a pancreatic cancer if at least one of the eg markers cg01237565 or cgl6561543 is hypermethylated. In other cases, the subject is determined to have a pancreatic cancer if eg marker cg08116711 is hypomethylated.

[0117] In some instances, the methylation status or pattern of at least one eg marker selected from cgl3771313, cgl3771313, and cg08169020 is used to determine whether the subject has acute myeloid leukemia.

[0118] In some instances, the methylation status or pattern of at least one eg marker selected from cg08169020, cg21153697, cg07326648, cgl4309384, cg20923716, cg22220310, cg21950459, cgl3332729, cgl0802543, cg20707333, and cgl3169641 is used to determine whether the subject has cervical cancer. In some instances, the subject is determined to have cervical cancer if at least one of the eg markers cg08169020, cg21153697, cg07326648, cgl4309384, or cg20923716 is hypermethylated. In other instances, the subject is determined to have cervical cancer if at least one of the eg markers cg22220310, cg21950459, cgl3332729, egl 0802543, cg20707333, or egl 3169641 is hypomethylated.

[0119] In some instances, the methylation status or pattern of one eg marker cg09095222 is used to determine whether the subject has sarcoma. In some cases, the subject is determined to have sarcoma if at least eg marker cg09095222 is hypermethylated.

[0120] In some instances, the methylation status or pattern of at least one eg marker selected from cg00736681 and cgl 8834029 is used to determine whether the subject has stomach cancer. In some cases, the subject is determined to have stomach cancer if at least one of the eg markers cg00736681 or cgl 8834029 is hypomethylated.

[0121] In some instances, the methylation status or pattern of at least one eg marker selected from cg06969479, cg24630516, and egl 6901821 is used to determine if the subject has thyroid cancer. In some cases, the subject is determined to have thyroid cancer if at least one of the eg markers cg06969479, cg24630516, or cgl6901821 is hypomethylated.

[0122] In some instances, the methylation status or pattern of eg marker cg05630192 is used to determine whether the subject has mesothelioma. In some cases, the subject is determined to have mesothelioma if eg marker cg05630192 is hypomethylated.

[0123] In some instances, the methylation status or pattern of eg marker cg06405341 is used to determine whether the subject has glioblastoma.

[0124] In some instances, the methylation status or pattern of at least one eg marker selected from cg08557188, cg00690392, cg03421440, and cg07077277 is used to determine whether the subject has lung cancer. In some cases, the subject is determined to have lung cancer if at least one of the eg markers cg08557188, cg00690392, cg03421440, or cg07077277 is hypomethylated.

[0125] In some embodiments, the methylation status or pattern of one or more genes selected from MYOIG, ADAMTS4, BMPR1A, CD6, RBP5, Chr 13 : 10, LGAP5, ATXN1, Chr 8:20, or a combination thereof is further used to determine whether the subject has a cancer. In some instances, the methylation status of one or more genes selected from MYOIG, ADAMTS4, BMPR1A, CD6, RBP5, Chr 13: 10, LGAP5, ATXN1, Chr 8:20, or a combination thereof is further used to determine whether the subject has a colorectal cancer.

[0126] In some embodiments, also disclosed herein is a method of determining the prognosis of a cancer in a subject in need thereof based on the methylation status of a set of eg markers. In some embodiments, the method comprises (a) processing a biological sample obtained from a subject with a deaminating agent to generate treated DNA comprising deaminated nucleotides; (b) contacting the treated DNA with at least one probe that hybridizes under high stringency condition to a target sequence of cgl0673833 or cg25462303; and (c) quantitatively detecting the methylation status of the eg marker, wherein said detection comprises a real-time quantitative probe-based PCR or a digital probe-based PCR. In some instances, the cancer is a colorectal cancer. In some cases, the method of determining the prognosis of a colorectal cancer a subject in need thereof comprises (a) processing a biological sample obtained from a subject with a deaminating agent to generate treated DNA comprising deaminated nucleotides; (b) contacting the treated DNA with at least one probe that hybridizes under high stringency condition to a target sequence of cgl0673833 or cg25462303; and (c) quantitatively detecting the methylation status of the eg marker, wherein said detection comprises a real-time quantitative probe-based PCR or a digital probe-based PCR. In some cases, the methylation status of cgl0673833, cg25462303, or a combination thereof is used for monitoring a treatment progression of a subject in need thereof. In additional cases, the methylation status of cgl0673833, cg25462303, or a combination thereof is used as an early predictor of developing a cancer (e.g., CRC) of a subject in need thereof.

[0127] In some embodiments, additional disclosed herein is a method of determining the prognosis of a cancer in a subject in need thereof, comprising (a) processing a biological sample obtained from a subject with a deaminating agent to generate treated DNA comprising deaminated nucleotides; (b) contacting the treated DNA with at least one probe that hybridizes under high stringency condition to a target sequence of cg05205843, egl 1841704, cg06699564, cg08924619, cgl l959316, cg08924619, cg06699564, cg01824933, cg08924619, cg05205842, cg08924619, cg04049981, cg09026722, cg03616722, cg08924619, cg05928904, cg08704934, cg09776772, cgl7494199, cg01824933, cgl6296417, cg09776772, cg09776772, cg05338167, cgl0493436, cgOl 1251410, cgl6391792, cg06393830, cg09366118, cg22513455, cgl7583432, cg23881926, cg09638208, cgl2441066, cg27284288, cg04441857, cgl7583432, cgl0673833, cgl9757176, cg08670281, cgl7583432, cg04460364, cgl6959747, cgl5011734, or cg25754195; and (c) quantitatively detecting the methylation status of the eg marker, wherein said detection comprises a real-time quantitative probe-based PCR or a digital probe-based PCR. In some instances, the cancer is a colorectal cancer. In some cases, the method of determining the prognosis of a colorectal cancer a subject in need thereof comprises (a) processing a biological sample obtained from a subject with a deaminating agent to generate treated DNA comprising deaminated nucleotides; (b) contacting the treated DNA with at least one probe that hybridizes under high stringency condition to a target sequence of cg05205843, cgl 1841704, cg06699564, cg08924619, cgl l959316, cg08924619, cg06699564, cg01824933, cg08924619, cg05205842, cg08924619, cg04049981, cg09026722, cg03616722, cg08924619, cg05928904, cg08704934, cg09776772, cgl7494199, cg01824933, cgl6296417, cg09776772, cg09776772, cg05338167, cgl0493436, cgOl 1251410, cgl6391792, cg06393830, cg09366118, cg22513455, cgl7583432, cg23881926, cg09638208, cgl2441066, cg27284288, cg04441857, cgl7583432, cgl0673833, cgl9757176, cg08670281, cgl7583432, cg04460364, cgl6959747, cgl5011734, or cg25754195; and (c) quantitatively detecting the methylation status of the eg marker, wherein said detection comprises a real-time quantitative probe-based PCR or a digital probe-based PCR.

[0128] In some instances, if one or more eg markers cg06393830, cg09366118, cg22513455, cgl7583432, cg23881926, cg09638208, cgl2441066, cg27284288, cg04441857, cgl7583432, cgl0673833, cgl9757176, cg08670281, cgl7583432, cg04460364, cgl6959747, cgl5011734, or cg25754195 are hypermethylated, the prognosis of the cancer is correlated with an advanced tumor stage and poor survival.

[0129] In some cases, the methylation status or pattern of cg05205843, cgl 1841704, cg06699564, cg08924619, cgl l959316, cg08924619, cg06699564, cg01824933, cg08924619, cg05205842, cg08924619, cg04049981, cg09026722, cg03616722, cg08924619, cg05928904, cg08704934, cg09776772, cgl7494199, cg01824933, cgl6296417, cg09776772, cg09776772, cg05338167, cgl0493436, cgOl 1251410, cgl6391792, cg06393830, cg09366118, cg22513455, cgl7583432, cg23881926, cg09638208, cgl2441066, cg27284288, cg04441857, cgl7583432, cgl0673833, cgl9757176, cg08670281, cgl7583432, cg04460364, cgl6959747, cgl5011734, cg25754195, or a combination thereof is used for monitoring a treatment progression of a subject in need thereof. In additional cases, the methylation status of cg05205843, cgl 1841704, cg06699564, cg08924619, cgl l959316, cg08924619, cg06699564, cg01824933, cg08924619, cg05205842, cg08924619, cg04049981, cg09026722, cg03616722, cg08924619, cg05928904, cg08704934, cg09776772, cgl7494199, cg01824933, cgl6296417, cg09776772, cg09776772, cg05338167, cgl0493436, cgOl 1251410, cgl6391792, cg06393830, cg09366118, cg22513455, cgl7583432, cg23881926, cg09638208, cgl2441066, cg27284288, cg04441857, cgl7583432, cgl0673833, cgl9757176, cg08670281, cgl7583432, cg04460364, cgl6959747, cgl5011734, cg25754195, or a combination thereof is used as an early predictor of developing a cancer (e.g., CRC) of a subject in need thereof.

[0130] In some embodiments, the methylation status or pattern of one or more biomarkers selected from 3-49757316, 8-27183116, 8-141607252, 17-29297711, 3-49757306, 19-43979341, 8-141607236, 5-176829755, 18-13382140, 15-65341965, 3-13152305, 17-29297770, 8- 27183316, 5-176829740, 19-41316693, 18-43830649, 15-65341957, 20-44539531, 7-30265625, 2-131129567, 5-176829665, 3-13152273, 8-27183348, 3-49757302, 19-41316697, 8-61821442, 20-44539525, 10-102883105, 11-65849129, 5-176829639, 15-91129457, 2-1625431, 6- 151373292, 6-151373294, 20-25027093, 6-14284198, 10-4049295, 19-59023222, 1-184197132, 2-131004117, 2-8995417, 12-10782319, 20-25027033, 6-151373256, 8-86100970, 9-4839459, 17-41221574, 1-153926715, 20-25027044, 20-20177325, 2-1625443, 20-25027085, 11- 69420728, 1-229234865, 6-13408877, 22-50643735, 6-151373308, 1-232119750, 8-134361508, or 6-13408858 is used for determining the prognosis of a subject having a liver cancer. In additional cases, the methylation status or pattern of one or more biomarkers selected from 3- 49757316, 8-27183116, 8-141607252, 17-29297711, 3-49757306, 19-43979341, 8-141607236, 5-176829755, 18-13382140, 15-65341965, 3-13152305, 17-29297770, 8-27183316, 5- 176829740, 19-41316693, 18-43830649, 15-65341957, 20-44539531, 7-30265625, 2- 131129567, 5-176829665, 3-13152273, 8-27183348, 3-49757302, 19-41316697, 8-61821442, 20-44539525, 10-102883105, 11-65849129, 5-176829639, 15-91129457, 2-1625431, 6- 151373292, 6-151373294, 20-25027093, 6-14284198, 10-4049295, 19-59023222, 1-184197132, 2-131004117, 2-8995417, 12-10782319, 20-25027033, 6-151373256, 8-86100970, 9-4839459, 17-41221574, 1-153926715, 20-25027044, 20-20177325, 2-1625443, 20-25027085, 11- 69420728, 1-229234865, 6-13408877, 22-50643735, 6-151373308, 1-232119750, 8-134361508, or 6-13408858 is used for monitoring a treatment progression of a subject having a liver cancer.

[0131] In some instances, the biological sample is a blood sample, a urine sample, a saliva sample, a sweat sample, or a tear sample. In some cases, the biological sample is a blood sample or a urine sample. In some cases, the biological sample is a tissue biopsy sample. In some cases, the biological sample is a cell-free DNA sample. In some cases, the biological sample comprises circulating tumor cells.

Detection Methods

[0132] In some embodiments, a number of methods are utilized to measure, detect, determine, identify, and characterize the methylation status/level of a gene or a biomarker (e.g., CpG island- containing region/fragment) in identifying a subject as having liver cancer, determining the liver cancer subtype, the prognosis of a subject having liver cancer, and the progression or regression of liver cancer in subject in the presence of a therapeutic agent.

[0133] In some instances, the methylation profile is generated from a biological sample isolated from an individual. In some embodiments, the biological sample is a biopsy. In some instances, the biological sample is a tissue sample. In some instances, the biological sample is a tissue biopsy sample. In some instances, the biological sample is a blood sample. In other instances, the biological sample is a cell-free biological sample. In other instances, the biological sample is a circulating tumor DNA sample. In one embodiment, the biological sample is a cell free biological sample containing circulating tumor DNA.

[0134] In some embodiments, a biomarker (or an epigenetic marker) is obtained from a liquid sample. In some embodiments, the liquid sample comprises blood and other liquid samples of biological origin (including, but not limited to, peripheral blood, sera, plasma, ascites, urine, cerebrospinal fluid (CSF), sputum, saliva, bone marrow, synovial fluid, aqueous humor, amniotic fluid, cerumen, breast milk, broncheoalveolar lavage fluid, semen, prostatic fluid, cowper's fluid or pre-ejaculatory fluid, female ejaculate, sweat, tears, cyst fluid, pleural and peritoneal fluid, pericardial fluid, ascites, lymph, chyme, chyle, bile, interstitial fluid, menses, pus, sebum, vomit, vaginal secretions/flushing, synovial fluid, mucosal secretion, stool water, pancreatic juice, lavage fluids from sinus cavities, bronchopulmonary aspirates, blastocyl cavity fluid, or umbilical cord blood. In some embodiments, the biological fluid is blood, a blood derivative or a blood fraction, e.g., serum or plasma. In a specific embodiment, a sample comprises a blood sample. In another embodiment, a serum sample is used. In another embodiment, a sample comprises urine. In some embodiments, the liquid sample also encompasses a sample that has been manipulated in any way after their procurement, such as by centrifugation, filtration,

precipitation, dialysis, chromatography, treatment with reagents, washed, or enriched for certain cell populations.

[0135] In some embodiments, a biomarker (or an epigenetic marker) is obtained from a tissue sample. In some instances, a tissue corresponds to any cell(s). Different types of tissue correspond to different types of cells (e.g., liver, lung, blood, connective tissue, and the like), but also healthy cells vs. tumor cells or to tumor cells at various stages of neoplasia, or to displaced malignant tumor cells. In some embodiments, a tissue sample further encompasses a clinical sample, and also includes cells in culture, cell supematants, organs, and the like. Samples also comprise fresh-frozen and/or formalin- fixed, paraffin-embedded tissue blocks, such as blocks prepared from clinical or pathological biopsies, prepared for pathological analysis or study by immunohistochemistry.

[0136] In some embodiments, a biomarker (or an epigenetic marker) is methylated or unmethylated in a normal sample (e.g., normal or control tissue without disease, or normal or control body fluid, stool, blood, serum, amniotic fluid), most importantly in healthy stool, blood, serum, amniotic fluid or other body fluid. In other embodiments, a biomarker (or an epigenetic marker) is hypomethylated or hypermethylated in a sample from a patient having or at risk of a disease (e.g., one or more indications described herein); for example, at a decreased or increased (respectively) methylation frequency of at least about 50%, at least about 60%, at least about 70%, at least about 75%, at least about 80%, at least about 85%, at least about 90%, at least about 95%, or about 100% in comparison to a normal sample. In one embodiment, a sample is also hypomethylated or hypermethylated in comparison to a previously obtained sample analysis of the same patient having or at risk of a disease (e.g., one or more indications described herein), particularly to compare progression of a disease.

[0137] In some embodiments, a methylome comprises a set of epigenetic markers or biomarkers, such as a biomarker described above. In some instances, a methylome that corresponds to the methylome of a tumor of an organism (e.g., a human) is classified as a tumor methylome. In some cases, a tumor methylome is determined using tumor tissue or cell-free (or protein-free) tumor DNA in a biological sample. Other examples of methylomes of interest include the methylomes of organs that contribute DNA into a bodily fluid (e.g. methylomes of tissue such as brain, breast, lung, the prostrate and the kidneys, plasma, etc.).

[0138] In some embodiments, a plasma methylome is the methylome determined from the plasma or serum of an animal (e.g., a human). In some instances, the plasma methylome is an example of a cell-free or protein-free methylome since plasma and serum include cell-free DNA. The plasma methylome is also an example of a mixed methylome since it is a mixture of tumor and other methylomes of interest. In some instances, the urine methylome is determined from the urine sample of a subject. In some cases, a cellular methylome corresponds to the methylome determined from cells (e.g., blood cells) of the patient. The methylome of the blood cells is called the blood cell methylome (or blood methylome).

[0139] In some embodiments, DNA (e.g., genomic DNA such as extracted genomic DNA or treated genomic DNA) is isolated by any means standard in the art, including the use of commercially available kits. Briefly, wherein the DNA of interest is encapsulated in by a cellular membrane the biological sample is disrupted and lysed by enzymatic, chemical or mechanical means. In some cases, the DNA solution is then cleared of proteins and other contaminants e.g. by digestion with proteinase K. The DNA is then recovered from the solution. In such cases, this is carried out by means of a variety of methods including salting out, organic extraction or binding of the DNA to a solid phase support. In some instances, the choice of method is affected by several factors including time, expense and required quantity of DNA.

[0140] Wherein the sample DNA is not enclosed in a membrane (e.g. circulating DNA from a cell free sample such as blood or urine) methods standard in the art for the isolation and/or purification of DNA are optionally employed (See, for example, Bettegowda et al. Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies. Sci. Transl. Med, 6(224): ra24. 2014). Such methods include the use of a protein degenerating reagent e.g.

chaotropic salt e.g. guanidine hydrochloride or urea; or a detergent e.g. sodium dodecyl sulphate (SDS), cyanogen bromide. Alternative methods include but are not limited to ethanol precipitation or propanol precipitation, vacuum concentration amongst others by means of a centrifuge. In some cases, the person skilled in the art also make use of devices such as filter devices e.g. ultrafiltration, silica surfaces or membranes, magnetic particles, polystyrol particles, polystyrol surfaces, positively charged surfaces, and positively charged membranes, charged membranes, charged surfaces, charged switch membranes, and charged switched surfaces.

[0141] In some instances, once the nucleic acids have been extracted, methylation analysis is carried out by any means known in the art. A variety of methylation analysis procedures is known in the art and may be used to practice the methods disclosed herein. These assays allow for determination of the methylation state of one or a plurality of CpG sites within a tissue sample. In addition, these methods may be used for absolute or relative quantification of methylated nucleic acids. Such methylation assays involve, among other techniques, two major steps. The first step is a methylation specific reaction or separation, such as (i) bisulfite treatment, (ii) methylation specific binding, or (iii) methylation specific restriction enzymes. The second major step involves (i) amplification and detection, or (ii) direct detection, by a variety of methods such as (a) PCR (sequence-specific amplification) such as Taqman(R), (b) DNA sequencing of untreated and bisulfite-treated DNA, (c) sequencing by ligation of dye-modified probes (including cyclic ligation and cleavage), (d) pyrosequencing, (e) single-molecule sequencing, (f) mass spectroscopy, or (g) Southern blot analysis.

[0142] Additionally, restriction enzyme digestion of PCR products amplified from bisulfite - converted DNA may be used, e.g., the method described by Sadri and Hornsby (1996, Nucl. Acids Res. 24:5058- 5059), or COBRA (Combined Bisulfite Restriction Analysis) (Xiong and Laird, 1997, Nucleic Acids Res. 25:2532- 2534). COBRA analysis is a quantitative methylation assay useful for determining DNA methylation levels at specific gene loci in small amounts of genomic DNA. Briefly, restriction enzyme digestion is used to reveal methylation-dependent sequence differences in PCR products of sodium bisulfite- treated DNA. Methylation-dependent sequence differences are first introduced into the genomic DNA by standard bisulfite treatment according to the procedure described by Frommer et al. (Frommer et al, 1992, Proc. Nat. Acad. Sci. USA, 89, 1827-1831). PCR amplification of the bisulfite converted DNA is then performed using primers specific for the CpG sites of interest, followed by restriction endonuclease digestion, gel electrophoresis, and detection using specific, labeled hybridization probes.

Methylation levels in the original DNA sample are represented by the relative amounts of digested and undigested PCR product in a linearly quantitative fashion across a wide spectrum of DNA methylation levels. In addition, this technique can be reliably applied to DNA obtained from micro-dissected paraffin- embedded tissue samples. Typical reagents (e.g., as might be found in a typical COBRA- based kit) for COBRA analysis may include, but are not limited to: PCR primers for specific gene (or methylation-altered DNA sequence or CpG island); restriction enzyme and appropriate buffer; gene-hybridization oligo; control hybridization oligo; kinase labeling kit for oligo probe; and radioactive nucleotides. Additionally, bisulfite conversion reagents may include: DNA denaturation buffer; sulfo nation buffer; DNA recovery reagents or kits (e.g., precipitation, ultrafiltration, affinity column); desulfonation buffer; and DNA recovery components.

[0143] In an embodiment, the methylation profile of selected CpG sites is determined using methylation-Specific PCR (MSP). MSP allows for assessing the methylation status of virtually any group of CpG sites within a CpG island, independent of the use of methylation- sensitive restriction enzymes (Herman et al, 1996, Proc. Nat. Acad. Sci. USA, 93, 9821- 9826; U.S. Pat. Nos. 5,786,146, 6,017,704, 6,200,756, 6,265,171 (Herman and Baylin); U.S. Pat. Pub. No.

2010/0144836 (Van Engeland et al); which are hereby incorporated by reference in their entirety). Briefly, DNA is modified by a deaminating agent such as sodium bisulfite to convert unmethylated, but not methylated cytosines to uracil, and subsequently amplified with primers specific for methylated versus unmethylated DNA. In some instances, typical reagents (e.g., as might be found in a typical MSP- based kit) for MSP analysis include, but are not limited to: methylated and unmethylated PCR primers for specific gene (or methylation- altered DNA sequence or CpG island), optimized PCR buffers and deoxynucleotides, and specific probes. One may use quantitative multiplexed methylation specific PCR (QM-PCR), as described by Fackler et al. Fackler et al, 2004, Cancer Res. 64(13) 4442-4452; or Fackler et al, 2006, Clin. Cancer Res. 12(11 Pt 1) 3306-3310.

[0144] In an embodiment, the methylation profile of selected CpG sites is determined using MethyLight and/or Heavy Methyl Methods. The MethyLight and Heavy Methyl assays are a high-throughput quantitative methylation assay that utilizes fluorescence- based real-time PCR (Taq Man(R)) technology that requires no further manipulations after the PCR step (Eads, C.A. et al, 2000, Nucleic Acid Res. 28, e 32; Cottrell et al, 2007, J. Urology 177, 1753, U.S. Pat. Nos. 6,331,393 (Laird et al), the contents of which are hereby incorporated by reference in their entirety). Briefly, the MethyLight process begins with a mixed sample of genomic DNA that is converted, in a sodium bisulfite reaction, to a mixed pool of methylation-dependent sequence differences according to standard procedures (the bisulfite process converts unmethylated cytosine residues to uracil). Fluorescence-based PCR is then performed either in an "unbiased" (with primers that do not overlap known CpG methylation sites) PCR reaction, or in a "biased" (with PCR primers that overlap known CpG dinucleotides) reaction. In some cases, sequence discrimination occurs either at the level of the amplification process or at the level of the fluorescence detection process, or both. In some cases, the MethyLight assay is used as a quantitative test for methylation patterns in the genomic DNA sample, wherein sequence discrimination occurs at the level of probe hybridization. In this quantitative version, the PCR reaction provides for unbiased amplification in the presence of a fluorescent probe that overlaps a particular putative methylation site. An unbiased control for the amount of input DNA is provided by a reaction in which neither the primers, nor the probe overlie any CpG dinucleotides. Alternatively, a qualitative test for genomic methylation is achieved by probing of the biased PCR pool with either control oligonucleotides that do not "cover" known methylation sites (a fluorescence- based version of the "MSP" technique), or with oligonucleotides covering potential methylation sites. Typical reagents (e.g., as might be found in a typical MethyLight- based kit) for MethyLight analysis may include, but are not limited to: PCR primers for specific gene (or methylation-altered DNA sequence or CpG island); TaqMan(R) probes; optimized PCR buffers and deoxynucleotides; and Taq polymerase.

[0145] Quantitative MethyLight uses bisulfite to convert genomic DNA and the methylated sites are amplified using PCR with methylation independent primers. Detection probes specific for the methylated and unmethylated sites with two different fluorophores provides simultaneous quantitative measurement of the methylation. The Heavy Methyl technique begins with bisulfate conversion of DNA. Next specific blockers prevent the amplification of unmethylated DNA. Methylated genomic DNA does not bind the blockers and their sequences will be amplified. The amplified sequences are detected with a methylation specific probe. (Cottrell et al, 2004, Nuc. Acids Res. 32:el0, the contents of which is hereby incorporated by reference in its entirety).

[0146] The Ms-SNuPE technique is a quantitative method for assessing methylation differences at specific CpG sites based on bisulfite treatment of DNA, followed by single- nucleotide primer extension (Gonzalgo and Jones, 1997, Nucleic Acids Res. 25, 2529-2531). Briefly, genomic DNA is reacted with sodium bisulfite to convert unmethylated cytosine to uracil while leaving 5 -methyl cytosine unchanged. Amplification of the desired target sequence is then performed using PCR primers specific for bisulfite-converted DNA, and the resulting product is isolated and used as a template for methylation analysis at the CpG site(s) of interest. In some cases, small amounts of DNA are analyzed (e.g., micro-dissected pathology sections), and the method avoids utilization of restriction enzymes for determining the methylation status at CpG sites. Typical reagents (e.g., as is found in a typical Ms-SNuPE-based kit) for Ms- SNuPE analysis include, but are not limited to: PCR primers for specific gene (or methylation-altered DNA sequence or CpG island); optimized PCR buffers and deoxynucleotides; gel extraction kit; positive control primers; Ms-SNuPE primers for specific gene; reaction buffer (for the Ms- SNuPE reaction); and radioactive nucleotides. Additionally, bisulfite conversion reagents may include: DNA denaturation buffer; sulfonation buffer; DNA recovery regents or kit (e.g., precipitation, ultrafiltration, affinity column); desulfonation buffer; and DNA recovery components.

[0147] In another embodiment, the methylation status of selected CpG sites is determined using differential Binding-based Methylation Detection Methods. For identification of differentially methylated regions, one approach is to capture methylated DNA. This approach uses a protein, in which the methyl binding domain of MBD2 is fused to the Fc fragment of an antibody (MBD-FC) (Gebhard et al, 2006, Cancer Res. 66:6118-6128; and PCT Pub. No. WO 2006/056480 A2 (Relhi), the contents of which are hereby incorporated by reference in their entirety). This fusion protein has several advantages over conventional methylation specific antibodies. The MBD FC has a higher affinity to methylated DNA and it binds double stranded DNA. Most importantly the two proteins differ in the way they bind DNA. Methylation specific antibodies bind DNA stochastically, which means that only a binary answer can be obtained. The methyl binding domain of MBD-FC, on the other hand, binds DNA molecules regardless of their methylation status. The strength of this protein - DNA interaction is defined by the level of DNA methylation. After binding genomic DNA, eluate solutions of increasing salt concentrations can be used to fractionate non- methylated and methylated DNA allowing for a more controlled separation (Gebhard et al, 2006, Nucleic Acids Res. 34: e82). Consequently this method, called Methyl-CpG immunoprecipitation (MCIP), not only enriches, but also fractionates genomic DNA according to methylation level, which is particularly helpful when the unmethylated DNA fraction should be investigated as well.

[0148] In an alternative embodiment, a 5 -methyl cytidine antibody to bind and precipitate methylated DNA. Antibodies are available from Abeam (Cambridge, MA), Diagenode (Sparta, NJ) or Eurogentec (c/o AnaSpec, Fremont, CA). Once the methylated fragments have been separated they may be sequenced using microarray based techniques such as methylated CpG- island recovery assay (MIRA) or methylated DNA immunoprecipitation (MeDIP) (Pelizzola et al, 2008, Genome Res. 18, 1652-1659; O'Geen et al, 2006, BioTechniques 41(5), 577-580, Weber et al, 2005, Nat. Genet. 37, 853-862; Horak and Snyder, 2002, Methods Enzymol, 350, 469-83; Lieb, 2003, Methods Mol Biol, 224, 99-109). Another technique is methyl-CpG binding domain column/segregation of partly melted molecules (MBD/SPM, Shiraishi et al, 1999, Proc. Natl. Acad. Sci. USA 96(6):2913-2918).

[0149] In some embodiments, methods for detecting methylation include randomly shearing or randomly fragmenting the genomic DNA, cutting the DNA with a methylation-dependent or methylation-sensitive restriction enzyme and subsequently selectively identifying and/or analyzing the cut or uncut DNA. Selective identification can include, for example, separating cut and uncut DNA (e.g., by size) and quantifying a sequence of interest that was cut or,

alternatively, that was not cut. See, e.g., U.S. Patent No. 7,186,512. Alternatively, the method can encompass amplifying intact DNA after restriction enzyme digestion, thereby only amplifying DNA that was not cleaved by the restriction enzyme in the area amplified. See, e.g., U.S. Patents No. 7,910,296; No. 7,901,880; and No. 7,459,274. In some embodiments, amplification can be performed using primers that are gene specific. [0150] For example, there are methyl-sensitive enzymes that preferentially or substantially cleave or digest at their DNA recognition sequence if it is non-methylated. Thus, an

unmethylated DNA sample is cut into smaller fragments than a methylated DNA sample.

Similarly, a hypermethylated DNA sample is not cleaved. In contrast, there are methyl- sensitive enzymes that cleave at their DNA recognition sequence only if it is methylated. Methyl - sensitive enzymes that digest unmethylated DNA suitable for use in methods of the technology include, but are not limited to, Hpall, Hhal, Maell, BstUI and Acil. In some instances, an enzyme that is used is Hpall that cuts only the unmethylated sequence CCGG. In other instances, another enzyme that is used is Hhal that cuts only the unmethylated sequence GCGC. Both enzymes are available from New England BioLabs(R), Inc. Combinations of two or more methyl-sensitive enzymes that digest only unmethylated DNA are also used. Suitable enzymes that digest only methylated DNA include, but are not limited to, Dpnl, which only cuts at fully methylated 5'- GATC sequences, and McrBC, an endonuclease, which cuts DNA containing modified cytosines (5 -methyl cytosine or 5-hydroxymethylcytosine or N4- methylcytosine) and cuts at recognition site 5'... PumC(N4o-3ooo) PumC... 3' (New England BioLabs, Inc., Beverly, MA). Cleavage methods and procedures for selected restriction enzymes for cutting DNA at specific sites are well known to the skilled artisan. For example, many suppliers of restriction enzymes provide information on conditions and types of DNA sequences cut by specific restriction enzymes, including New England BioLabs, Promega Biochems, Boehringer-Mannheim, and the like. Sambrook et al. (See Sambrook et al. Molecular Biology: A Laboratory Approach, Cold Spring Harbor, N.Y. 1989) provide a general description of methods for using restriction enzymes and other enzymes.

[0151] In some instances, a methylation-dependent restriction enzyme is a restriction enzyme that cleaves or digests DNA at or in proximity to a methylated recognition sequence, but does not cleave DNA at or near the same sequence when the recognition sequence is not methylated. Methylation-dependent restriction enzymes include those that cut at a methylated recognition sequence (e.g., Dpnl) and enzymes that cut at a sequence near but not at the recognition sequence (e.g., McrBC). For example, McrBC's recognition sequence is 5' RmC (N40-3000) RmC 3 ' where "R" is a purine and "mC" is a methylated cytosine and "N40-3000" indicates the distance between the two RmC half sites for which a restriction event has been observed. McrBC generally cuts close to one half-site or the other, but cleavage positions are typically distributed over several base pairs, approximately 30 base pairs from the methylated base. McrBC sometimes cuts 3' of both half sites, sometimes 5' of both half sites, and sometimes between the two sites. Exemplary methylation-dependent restriction enzymes include, e.g., McrBC, McrA, MrrA, Bisl, Glal and Dpnl. One of skill in the art will appreciate that any methylation-dependent restriction enzyme, including homologs and orthologs of the restriction enzymes described herein, is also suitable for use with one or more methods described herein.

[0152] In some cases, a methylation-sensitive restriction enzyme is a restriction enzyme that cleaves DNA at or in proximity to an unmethylated recognition sequence but does not cleave at or in proximity to the same sequence when the recognition sequence is methylated. Exemplary methylation-sensitive restriction enzymes are described in, e.g., McClelland et al, 22(17) NUCLEIC ACIDS RES. 3640-59 (1994). Suitable methylation-sensitive restriction enzymes that do not cleave DNA at or near their recognition sequence when a cytosine within the recognition sequence is methylated at position C5 include, e.g., Aat Π, Aci I, Acd I, Age I, Alu I, Asc I, Ase I, AsiS I, Bbe I, BsaA I, BsaH I, BsiE I, BsiW I, BsrF I, BssH II, BssK I, BstB I, BstN I, BstU I, Cla I, Eae I, Eag I, Fau I, Fse I, Hha I, HinPl I, HinC II, Hpa II, Hpy99 I, HpyCH4 IV, Kas I, Mbo I, Mlu I, MapAl I, Msp I, Nae I, Nar I, Not I, Pml I, Pst I, Pvu I, Rsr II, Sac Π, Sap I, Sau3A I, Sfl I, Sfo I, SgrA I, Sma I, SnaB I, Tsc I, Xma I, and Zra I. Suitable methylation-sensitive restriction enzymes that do not cleave DNA at or near their recognition sequence when an adenosine within the recognition sequence is methylated at position N6 include, e.g., Mbo I. One of skill in the art will appreciate that any methylation-sensitive restriction enzyme, including homologs and orthologs of the restriction enzymes described herein, is also suitable for use with one or more of the methods described herein. One of skill in the art will further appreciate that a methylation-sensitive restriction enzyme that fails to cut in the presence of methylation of a cytosine at or near its recognition sequence may be insensitive to the presence of methylation of an adenosine at or near its recognition sequence. Likewise, a methylation-sensitive restriction enzyme that fails to cut in the presence of methylation of an adenosine at or near its recognition sequence may be insensitive to the presence of methylation of a cytosine at or near its recognition sequence. For example, Sau3AI is sensitive (i.e., fails to cut) to the presence of a methylated cytosine at or near its recognition sequence, but is insensitive (i.e., cuts) to the presence of a methylated adenosine at or near its recognition sequence. One of skill in the art will also appreciate that some methylation-sensitive restriction enzymes are blocked by methylation of bases on one or both strands of DNA encompassing of their recognition sequence, while other methylation-sensitive restriction enzymes are blocked only by methylation on both strands, but can cut if a recognition site is hemi -methylated.

[0153] In alternative embodiments, adaptors are optionally added to the ends of the randomly fragmented DNA, the DNA is then digested with a methylation-dependent or methylation- sensitive restriction enzyme, and intact DNA is subsequently amplified using primers that hybridize to the adaptor sequences. In this case, a second step is performed to determine the presence, absence or quantity of a particular gene in an amplified pool of DNA. In some embodiments, the DNA is amplified using real-time, quantitative PCR. [0154] In other embodiments, the methods comprise quantifying the average methylation density in a target sequence within a population of genomic DNA. In some embodiments, the method comprises contacting genomic DNA with a methylation-dependent restriction enzyme or methylation-sensitive restriction enzyme under conditions that allow for at least some copies of potential restriction enzyme cleavage sites in the locus to remain uncleaved; quantifying intact copies of the locus; and comparing the quantity of amplified product to a control value representing the quantity of methylation of control DNA, thereby quantifying the average methylation density in the locus compared to the methylation density of the control DNA.

[0155] In some instances, the quantity of methylation of a locus of DNA is determined by providing a sample of genomic DNA comprising the locus, cleaving the DNA with a restriction enzyme that is either methylation-sensitive or methylation-dependent, and then quantifying the amount of intact DNA or quantifying the amount of cut DNA at the DNA locus of interest. The amount of intact or cut DNA will depend on the initial amount of genomic DNA containing the locus, the amount of methylation in the locus, and the number (i.e., the fraction) of nucleotides in the locus that are methylated in the genomic DNA. The amount of methylation in a DNA locus can be determined by comparing the quantity of intact DNA or cut DNA to a control value representing the quantity of intact DNA or cut DNA in a similarly -treated DNA sample. The control value can represent a known or predicted number of methylated nucleotides.

Alternatively, the control value can represent the quantity of intact or cut DNA from the same locus in another (e.g., normal, non-diseased) cell or a second locus.

[0156] By using at least one methylation-sensitive or methylation-dependent restriction enzyme under conditions that allow for at least some copies of potential restriction enzyme cleavage sites in the locus to remain uncleaved and subsequently quantifying the remaining intact copies and comparing the quantity to a control, average methylation density of a locus can be determined. If the methylation-sensitive restriction enzyme is contacted to copies of a DNA locus under conditions that allow for at least some copies of potential restriction enzyme cleavage sites in the locus to remain uncleaved, then the remaining intact DNA will be directly

proportional to the methylation density, and thus may be compared to a control to determine the relative methylation density of the locus in the sample. Similarly, if a methylation-dependent restriction enzyme is contacted to copies of a DNA locus under conditions that allow for at least some copies of potential restriction enzyme cleavage sites in the locus to remain uncleaved, then the remaining intact DNA will be inversely proportional to the methylation density, and thus may be compared to a control to determine the relative methylation density of the locus in the sample. Such assays are disclosed in, e.g., U.S. Patent No. 7,910,296.

[0157] The methylated CpG island amplification (MCA) technique is a method that can be used to screen for altered methylation patterns in genomic DNA, and to isolate specific sequences associated with these changes (Toyota et al, 1999, Cancer Res. 59, 2307-2312, U.S. Pat. No. 7,700,324 (Issa et al), the contents of which are hereby incorporated by reference in their entirety). Briefly, restriction enzymes with different sensitivities to cytosine methylation in their recognition sites are used to digest genomic DNAs from primary tumors, cell lines, and normal tissues prior to arbitrarily primed PCR amplification. Fragments that show differential methylation are cloned and sequenced after resolving the PCR products on high-resolution polyacrylamide gels. The cloned fragments are then used as probes for Southern analysis to confirm differential methylation of these regions. Typical reagents (e.g., as might be found in a typical MCA-based kit) for MCA analysis may include, but are not limited to: PCR primers for arbitrary priming Genomic DNA; PCR buffers and nucleotides, restriction enzymes and appropriate buffers; gene-hybridization oligos or probes; control hybridization oligos or probes.

[0158] Additional methylation detection methods include those methods described in, e.g., U.S. Patents No. 7,553,627; No. 6,331,393; U.S. Patent Serial No. 12/476,981; U.S. Patent Publication No. 2005/0069879; Rein, et al, 26(10) NUCLEIC ACIDS RES. 2255-64 (1998); and Olek et al, 17(3) NAT. GENET. 275-6 (1997).

[0159] In another embodiment, the methylation status of selected CpG sites is determined using Methylation- Sensitive High Resolution Melting (HRM). Recently, Wojdacz et al. reported methylation-sensitive high resolution melting as a technique to assess methylation. (Wojdacz and Dobrovic, 2007, Nuc. Acids Res. 35(6) e41; Wojdacz et al. 2008, Nat. Prot. 3(12) 1903-1908; Ba c et al, 2009 J. Mol. Diagn. 11 102- 108; and US Pat. Pub. No. 2009/0155791 (Wojdacz et al), the contents of which are hereby incorporated by reference in their entirety). A variety of commercially available real time PCR machines have HRM systems including the Roche LightCycler480, Corbett Research RotorGene6000, and the Applied Biosystems 7500. HRM may also be combined with other amplification techniques such as pyrosequencing as described by Candiloro et al. (Candiloro et al, 2011, Epigenetics 6(4) 500-507).

[0160] In another embodiment, the methylation status of selected CpG locus is determined using a primer extension assay, including an optimized PCR amplification reaction that produces amplified targets for analysis using mass spectrometry. The assay can also be done in multiplex. Mass spectrometry is a particularly effective method for the detection of polynucleotides associated with the differentially methylated regulatory elements. The presence of the polynucleotide sequence is verified by comparing the mass of the detected signal with the expected mass of the polynucleotide of interest. The relative signal strength, e.g., mass peak on a spectra, for a particular polynucleotide sequence indicates the relative population of a specific allele, thus enabling calculation of the allele ratio directly from the data. This method is described in detail in PCT Pub. No. WO 2005/012578A1 (Beaulieu et al), which is hereby incorporated by reference in its entirety. For methylation analysis, the assay can be adopted to detect bisulfite introduced methylation dependent C to T sequence changes. These methods are particularly useful for performing multiplexed amplification reactions and multiplexed primer extension reactions (e.g., multiplexed homogeneous primer mass extension (hME) assays) in a single well to further increase the throughput and reduce the cost per reaction for primer extension reactions.

[0161] Other methods for DNA methylation analysis include restriction landmark genomic scanning (RLGS, Costello et al, 2002, Meth. Mol Biol, 200, 53-70), methylation- sensitive- representational difference analysis (MS-RDA, Ushijima and Yamashita, 2009, Methods Mol Biol 507, 1 17-130). Comprehensive high-throughput arrays for relative methylation (CHARM) techniques are described in WO 2009/021141 (Feinberg and Irizarry). The Roche(R)

NimbleGen(R) microarrays including the Chromatin Immunoprecipitation-on- chip (ChlP-chip) or methylated DNA immunoprecipitation-on-chip (MeDIP-chip). These tools have been used for a variety of cancer applications including melanoma, liver cancer and lung cancer (Koga et al, 2009, Genome Res., 19, 1462-1470; Acevedo et al, 2008, Cancer Res., 68, 2641-2651; Rauch et al, 2008, Proc. Nat. Acad. Sci. USA, 105, 252-257). Others have reported bisulfate conversion, padlock probe hybridization, circularization, amplification and next generation or multiplexed sequencing for high throughput detection of methylation (Deng et al, 2009, Nat. Biotechnol 27, 353-360; Ball et al, 2009, Nat. Biotechnol 27, 361-368; U.S. Pat. No. 7,611,869 (Fan)). As an alternative to bisulfate oxidation, Bayeyt et al. have reported selective oxidants that oxidize 5- methylcytosine, without reacting with thymidine, which are followed by PCR or pyro sequencing (WO 2009/049916 (Bayeyt et al). These references for these techniques are hereby incorporated by reference in their entirety.

[0162] In some instances, quantitative amplification methods (e.g., quantitative PCR or quantitative linear amplification) are used to quantify the amount of intact DNA within a locus flanked by amplification primers following restriction digestion. Methods of quantitative amplification are disclosed in, e.g., U.S. Patents No. 6, 180,349; No. 6,033,854; and No.

5,972,602, as well as in, e.g., DeGraves, et al, 34(1) BIOTECHNIQUES 106-15 (2003); Deiman B, et al, 20(2) MOL. BIOTECHNOL. 163-79 (2002); and Gibson et al, 6 GENOME

RESEARCH 995-1001 (1996).

[0163] Following reaction or separation of nucleic acid in a methylation specific manner, the nucleic acid in some cases are subjected to sequence-based analysis. For example, once it is determined that one particular genomic sequence from a sample is hypermethylated or hypomethylated compared to its counterpart, the amount of this genomic sequence can be determined. Subsequently, this amount can be compared to a standard control value and used to determine the present of liver cancer in the sample. In many instances, it is desirable to amplify a nucleic acid sequence using any of several nucleic acid amplification procedures which are well known in the art. Specifically, nucleic acid amplification is the chemical or enzymatic synthesis of nucleic acid copies which contain a sequence that is complementary to a nucleic acid sequence being amplified (template). The methods and kits may use any nucleic acid amplification or detection methods known to one skilled in the art, such as those described in U.S. Pat. Nos.

5,525,462 (Takarada et al); 6,114,117 (Hepp et al); 6,127,120 (Graham et al); 6,344,317

(Urnovitz); 6,448,001 (Oku); 6,528,632 (Catanzariti et al); and PCT Pub. No. WO 2005/111209 (Nakajima et al); all of which are incorporated herein by reference in their entirety.

[0164] In some embodiments, the nucleic acids are amplified by PCR amplification using methodologies known to one skilled in the art. One skilled in the art will recognize, however, that amplification can be accomplished by any known method, such as ligase chain reaction (LCR), Q -replicas amplification, rolling circle amplification, transcription amplification, self- sustained sequence replication, nucleic acid sequence-based amplification (NASBA), each of which provides sufficient amplification. Branched-DNA technology is also optionally used to qualitatively demonstrate the presence of a sequence of the technology, which represents a particular methylation pattern, or to quantitatively determine the amount of this particular genomic sequence in a sample. Nolte reviews branched-DNA signal amplification for direct quantitation of nucleic acid sequences in clinical samples (Nolte, 1998, Adv. Clin. Chem. 33:201 - 235).

[0165] The PCR process is well known in the art and include, for example, reverse

transcription PCR, ligation mediated PCR, digital PCR (dPCR), or droplet digital PCR (ddPCR). For a review of PCR methods and protocols, see, e.g., Innis et al, eds., PCR Protocols, A Guide to Methods and Application, Academic Press, Inc., San Diego, Calif. 1990; U.S. Pat. No. 4,683,202 (Mullis). PCR reagents and protocols are also available from commercial vendors, such as Roche Molecular Systems. In some instances, PCR is carried out as an automated process with a thermostable enzyme. In this process, the temperature of the reaction mixture is cycled through a denaturing region, a primer annealing region, and an extension reaction region automatically. Machines specifically adapted for this purpose are commercially available.

[0166] In some embodiments, amplified sequences are also measured using invasive cleavage reactions such as the Invader(R) technology (Zou et al, 2010, Association of Clinical Chemistry (AACC) poster presentation on July 28, 2010, "Sensitive Quantification of Methylated Markers with a Novel Methylation Specific Technology; and U.S. Pat. No. 7,011,944 (Prudent et al)).

[0167] Suitable next generation sequencing technologies are widely available. Examples include the 454 Life Sciences platform (Roche, Branford, CT) (Margulies et al. 2005 Nature, 437, 376-380); lllumina's Genome Analyzer, GoldenGate Methylation Assay, or Infinium Methylation Assays, i.e., Infinium HumanMethylation 27K BeadArray or VeraCode GoldenGate methylation array (Illumina, San Diego, CA; Bibkova et al, 2006, Genome Res. 16, 383-393; U.S. Pat. Nos. 6,306,597 and 7,598,035 (Macevicz); 7,232,656 (Balasubramanian et al.)); QX200™ Droplet Digital™ PCR System from Bio-Rad; or DNA Sequencing by Ligation, SOLiD System (Applied Biosystems/Life Technologies; U.S. Pat. Nos. 6,797,470, 7,083,917, 7,166,434, 7,320,865, 7,332,285, 7,364,858, and 7,429,453 (Barany et al); the Helicos True Single Molecule DNA sequencing technology (Harris et al, 2008 Science, 320, 106-109; U.S. Pat. Nos. 7,037,687 and 7,645,596 (Williams et al); 7, 169,560 (Lapidus et al); 7,769,400 (Harris)), the single molecule, real-time (SMRT™) technology of Pacific Biosciences, and sequencing (Soni and Meller, 2007, Clin. Chem. 53, 1996-2001); semiconductor sequencing (Ion Torrent; Personal Genome

Machine); DNA nanoball sequencing; sequencing using technology from Dover Systems (Polonator), and technologies that do not require amplification or otherwise transform native DNA prior to sequencing (e.g., Pacific Biosciences and Helicos), such as nanopore-based strategies (e.g., Oxford Nanopore, Genia Technologies, and Nabsys). These systems allow the sequencing of many nucleic acid molecules isolated from a specimen at high orders of multiplexing in a parallel fashion. Each of these platforms allows sequencing of clonally expanded or non-amplified single molecules of nucleic acid fragments. Certain platforms involve, for example, (i) sequencing by ligation of dye- modified probes (including cyclic ligation and cleavage), (ii) pyrosequencing, and (iii) single-molecule sequencing.

[0168] Pyrosequencing is a nucleic acid sequencing method based on sequencing by synthesis, which relies on detection of a pyrophosphate released on nucleotide incorporation. Generally, sequencing by synthesis involves synthesizing, one nucleotide at a time, a DNA strand complimentary to the strand whose sequence is being sought. Study nucleic acids may be immobilized to a solid support, hybridized with a sequencing primer, incubated with DNA polymerase, ATP sulfurylase, luciferase, apyrase, adenosine 5' phosphsulfate and luciferin.

Nucleotide solutions are sequentially added and removed. Correct incorporation of a nucleotide releases a pyrophosphate, which interacts with ATP sulfurylase and produces ATP in the presence of adenosine 5' phosphsulfate, fueling the luciferin reaction, which produces a chemiluminescent signal allowing sequence determination. Machines for pyrosequencing and methylation specific reagents are available from Qiagen, Inc. (Valencia, CA). See also Tost and Gut, 2007, Nat. Prot. 2 2265-2275. An example of a system that can be used by a person of ordinary skill based on pyrosequencing generally involves the following steps: ligating an adaptor nucleic acid to a study nucleic acid and hybridizing the study nucleic acid to a bead; amplifying a nucleotide sequence in the study nucleic acid in an emulsion; sorting beads using a picoliter multiwell solid support; and sequencing amplified nucleotide sequences by pyrosequencing methodology (e.g., Nakano et al, 2003, J. Biotech. 102, 117-124). Such a system can be used to exponentially amplify amplification products generated by a process described herein, e.g., by ligating a heterologous nucleic acid to the first amplification product generated by a process described herein.

CpG Methylation Data Analysis Methods

[0169] In certain embodiments, the methylation values measured for biomarkers of a biomarker panel are mathematically combined and the combined value is correlated to the underlying diagnostic question. In some instances, methylated biomarker values are combined by any appropriate state of the art mathematical method. Well-known mathematical methods for correlating a biomarker combination to a disease status employ methods like discriminant analysis (DA) (e.g., linear-, quadratic-, regularized-DA), Discriminant Functional Analysis (DFA), Kernel Methods (e.g., SVM), Multidimensional Scaling (MDS), Nonparametric Methods (e.g., k-Nearest-Neighbor Classifiers), PLS (Partial Least Squares), Tree-Based Methods (e.g., Logic Regression, CART, Random Forest Methods, Boosting/Bagging Methods), Generalized Linear Models (e.g., Logistic Regression), Principal Components based Methods (e.g., SIMCA), Generalized Additive Models, Fuzzy Logic based Methods, Neural Networks and Genetic Algorithms based Methods. The skilled artisan will have no problem in selecting an appropriate method to evaluate an epigenetic marker or biomarker combination described herein. In one embodiment, the method used in a correlating methylation status of an epigenetic marker or biomarker combination, e.g. to diagnose liver cancer or a liver cancer subtype, is selected from DA (e.g., Linear-, Quadratic-, Regularized Discriminant Analysis), DFA, Kernel Methods (e.g., SVM), MDS, Nonparametric Methods (e.g., k-Nearest-Neighbor Classifiers), PLS (Partial Least Squares), Tree-Based Methods (e.g., Logic Regression, CART, Random Forest Methods, Boosting Methods), or Generalized Linear Models (e.g., Logistic Regression), and Principal Components Analysis. Details relating to these statistical methods are found in the following references: Ruczinski et al, 12 J. OF COMPUTATIONAL AND GRAPHICAL STATISTICS 475-511 (2003); Friedman, J. H, 84 J. OF THE AMERICAN STATISTICAL ASSOCIATION 165-75 (1989); Hastie, Trevor, Tibshirani, Robert, Friedman, Jerome, The Elements of Statistical Leaming, Springer Series in Statistics (2001); Breiman, L., Friedman, J. H, Olshen, R. A., Stone, C. J. Classification and regression trees, California: Wadsworth (1984); Breiman, L., 45

MACHINE LEARNING 5-32 (2001); Pepe, M. S., The Statistical Evaluation of Medical Tests for Classification and Prediction, Oxford Statistical Science Series, 28 (2003); and Duda, R. O., Hart, P. E., Stork, D. O., Pattern Classification, Wiley Interscience, 2nd Edition (2001).

[0170] In one embodiment, the correlated results for each methylation panel are rated by their correlation to the disease or tumor type positive state, such as for example, by p-value test or t- value test or F-test. Rated (best first, i.e. low p- or t- value) biomarkers are then subsequently selected and added to the methylation panel until a certain diagnostic value is reached. Such methods include identification of methylation panels, or more broadly, genes that were differentially methylated among several classes using, for example, a random-variance t-test (Wright G. W. and Simon R, Bioinformatics 19:2448-2455,2003). Other methods include the step of specifying a significance level to be used for determining the epigenetic markers that will be included in the biomarker panel. Epigenetic markers that are differentially methylated between the classes at a univariate parametric significance level less than the specified threshold are included in the panel. It doesn't matter whether the specified significance level is small enough to exclude enough false discoveries. In some problems better prediction is achieved by being more liberal about the biomarker panels used as features. In some cases, the panels are biologically interpretable and clinically applicable, however, if fewer markers are included.

Similar to cross-validation, biomarker selection is repeated for each training set created in the cross-validation process. That is for the purpose of providing an unbiased estimate of prediction error. The methylation panel for use with new patient sample data is the one resulting from application of the methylation selection and classifier of the "known" methylation information, or control methylation panel.

[0171] Models for utilizing methylation profile to predict the class of future samples can also be used. These models may be based on the Compound Covariate Predictor (Radmacher et al. Journal of Computational Biology 9:505-511, 2002), Diagonal Linear Discriminant Analysis (Dudoit et al. Journal of the American Statistical Association 97:77-87, 2002), Nearest Neighbor Classification (also Dudoit et al.), and Support Vector Machines with linear kernel (Ramaswamy et al. PNAS USA 98: 15149-54, 2001). The models incorporated markers that were differentially methylated at a given significance level (e.g. 0.01, 0.05 or 0.1) as assessed by the random variance t-test (Wright G. W. and Simon R. Bioinformatics 19:2448-2455, 2003). The prediction error of each model using cross validation, preferably leave-one-out cross-validation (Simon et al. Journal of the National Cancer Institute 95: 14-18, 2003can be estimated. For each leave-one-out cross-validation training set, the entire model building process is repeated, including the epigenetic marker selection process. In some instances, it is also evaluated in whether the cross- validated error rate estimate for a model is significantly less than one would expect from random prediction. In some cases, the class labels are randomly permuted and the entire leave-one-out cross-validation process is then repeated. The significance level is the proportion of the random permutations that gives a cross-validated error rate no greater than the cross-validated error rate obtained with the real methylation data.

[0172] Another classification method is the greedy-pairs method described by Bo and Jonassen (Genome Biology 3(4):research0017.1-0017.11, 2002). The greedy-pairs approach starts with ranking all markers based on their individual t-scores on the training set. This method attempts to select pairs of markers that work well together to discriminate the classes. [0173] Furthermore, a binary tree classifier for utilizing methylation profile is optionally used to predict the class of future samples. The first node of the tree incorporated a binary classifier that distinguished two subsets of the total set of classes. The individual binary classifiers are based on the "Support Vector Machines" incorporating markers that were differentially expressed among markers at the significance level (e.g. 0.01, 0.05 or 0.1) as assessed by the random variance t-test (Wright G. W. and Simon R. Bioinformatics 19:2448-2455, 2003). Classifiers for all possible binary partitions are evaluated and the partition selected is that for which the cross- validated prediction error is minimum. The process is then repeated successively for the two subsets of classes determined by the previous binary split. The prediction error of the binary tree classifier can be estimated by cross-validating the entire tree building process. This overall cross- validation includes re-selection of the optimal partitions at each node and re-selection of the markers used for each cross-validated training set as described by Simon et al. (Simon et al. Journal of the National Cancer Institute 95: 14-18, 2003). Several-fold cross validation in which a fraction of the samples is withheld, a binary tree developed on the remaining samples, and then class membership is predicted for the samples withheld. This is repeated several times, each time withholding a different percentage of the samples. The samples are randomly partitioned into fractional test sets (Simon R and Lam A. BRB-ArrayTools User Guide, version 3.2. Biometric Research Branch, National Cancer Institute).

[0174] Thus, in one embodiment, the correlated results for each marker b) are rated by their correct correlation to the disease, preferably by p-value test. It is also possible to include a step in that the markers are selected d) in order of their rating.

[0175] In additional embodiments, factors such as the value, level, feature, characteristic, property, etc. of a transcription rate, mRNA level, translation rate, protein level, biological activity, cellular characteristic or property, genotype, phenotype, etc. can be utilized in addition prior to, during, or after administering a therapy to a patient to enable further analysis of the patient's cancer status.

[0176] In some embodiments, a diagnostic test to correctly predict status is measured as the sensitivity of the assay, the specificity of the assay or the area under a receiver operated characteristic ("ROC") curve. In some instances, sensitivity is the percentage of true positives that are predicted by a test to be positive, while specificity is the percentage of true negatives that are predicted by a test to be negative. In some cases, an ROC curve provides the sensitivity of a test as a function of 1 - specificity. The greater the area under the ROC curve, for example, the more accurate or powerful the predictive value of the test. Other useful measures of the utility of a test include positive predictive value and negative predictive value. Positive predictive value is the percentage of people who test positive that are actually positive. Negative predictive value is the percentage of people who test negative that are actually negative. [0177] In some embodiments, one or more of the biomarkers disclosed herein show a statistical difference in different samples of at least p<0.05, p<10 ^"2 , p<10 ^"3 , p<10 ^"4 or p<10 ^"5 . Diagnostic tests that use these biomarkers may show an ROC of at least 0.6, at least about 0.7, at least about 0.8, or at least about 0.9. In some instances, the biomarkers are differentially methylated in different subjects with or without liver cancer. In additional instances, the biomarkers for different subtypes of liver cancer are differentially methylated. In certain embodiments, the biomarkers are measured in a patient sample using the methods described herein and compared, for example, to predefined biomarker levels and are used to determine whether the patient has liver cancer, which liver cancer subtype does the patient have, and/or what is the prognosis of the patient having liver cancer. In other embodiments, the correlation of a combination of biomarkers in a patient sample is compared, for example, to a predefined set of biomarkers. In some embodiments, the measurement(s) is then compared with a relevant diagnostic amount(s), cut-off(s), or multivariate model scores that distinguish between the presence or absence of liver cancer, between liver cancer subtypes, and between a "good" or a "poor" prognosis. As is well understood in the art, by adjusting the particular diagnostic cut-off(s) used in an assay, one can increase sensitivity or specificity of the diagnostic assay depending on the preference of the diagnostician. In some embodiments, the particular diagnostic cut-off is determined, for example, by measuring the amount of biomarker hypermethylation or hypomethylation in a statistically significant number of samples from patients with or without liver cancer and from patients with different liver cancer subtypes, and drawing the cut-off to suit the desired levels of specificity and sensitivity.

Kits/Article of Manufacture

[0178] In some embodiments, provided herein include kits for detecting and/or characterizing the methylation profile of a biomarker described herein. In some instances, the kit comprises a plurality of primers or probes to detect or measure the methylation status/levels of one or more samples. Such kits comprise, in some instances, at least one polynucleotide that hybridizes to at least one of the methylation marker sequences described herein and at least one reagent for detection of gene methylation. Reagents for detection of methylation include, e.g., sodium bisulfate, polynucleotides designed to hybridize to sequence that is the product of a marker sequence if the marker sequence is not methylated (e.g., containing at least one C-U conversion), and/or a methylation- sensitive or methylation-dependent restriction enzyme. In some cases, the kits provide solid supports in the form of an assay apparatus that is adapted to use in the assay. In some instances, the kits further comprise detectable labels, optionally linked to a polynucleotide, e.g., a probe, in the kit. [0179] In some embodiments, the kits comprise one or more (e.g., 1, 2, 3, 4, or more) different polynucleotides (e.g., primers and/or probes) capable of specifically amplifying at least a portion of a DNA region of a biomarker described herein. Optionally, one or more detectably -labeled polypeptides capable of hybridizing to the amplified portion are also included in the kit. In some embodiments, the kits comprise sufficient primers to amplify 2, 3, 4, 5, 6, 7, 8, 9, 10, or more different DNA regions or portions thereof, and optionally include detectably -labeled

polynucleotides capable of hybridizing to each amplified DNA region or portion thereof. The kits further can comprise a methylation-dependent or methylation sensitive restriction enzyme and/or sodium bisulfite.

[0180] In some embodiments, the kits comprise sodium bisulfite, primers and adapters (e.g., oligonucleotides that can be ligated or otherwise linked to genomic fragments) for whole genome amplification, and polynucleotides (e.g., detectably-labeled polynucleotides) to quantify the presence of the converted methylated and or the converted unmethylated sequence of at least one cytosine from a DNA region of an epigenetic marker described herein.

[0181] In some embodiments, the kits comprise methylation sensing restriction enzymes (e.g., a methylation-dependent restriction enzyme and/or a methylation-sensitive restriction enzyme), primers and adapters for whole genome amplification, and polynucleotides to quantify the number of copies of at least a portion of a DNA region of an epigenetic marker described herein.

[0182] In some embodiments, the kits comprise a methylation binding moiety and one or more polynucleotides to quantify the number of copies of at least a portion of a DNA region of a marker described herein. A methylation binding moiety refers to a molecule (e.g., a polypeptide) that specifically binds to methyl-cytosine.

[0183] Examples include restriction enzymes or fragments thereof that lack DNA cutting activity but retain the ability to bind methylated DNA, antibodies that specifically bind to methylated DNA, etc.).

[0184] In some embodiments, the kit includes a packaging material. As used herein, the term "packaging material" can refer to a physical structure housing the components of the kit. In some instances, the packaging material maintains sterility of the kit components, and is made of material commonly used for such purposes (e.g., paper, corrugated fiber, glass, plastic, foil, ampules, etc.). Other materials useful in the performance of the assays are included in the kits, including test tubes, transfer pipettes, and the like. In some cases, the kits also include written instructions for the use of one or more of these reagents in any of the assays described herein.

[0185] In some embodiments, kits also include a buffering agent, a preservative, or a protein/nucleic acid stabilizing agent. In some cases, kits also include other components of a reaction mixture as described herein. For example, kits include one or more aliquots of thermostable DNA polymerase as described herein, and/or one or more aliquots of dNTPs. In some cases, kits also include control samples of known amounts of template DNA molecules harboring the individual alleles of a locus. In some embodiments, the kit includes a negative control sample, e.g., a sample that does not contain DNA molecules harboring the individual alleles of a locus. In some embodiments, the kit includes a positive control sample, e.g., a sample containing known amounts of one or more of the individual alleles of a locus.

Certain Terminology

[0186] Unless defined otherwise, all technical and scientific terms used herein have the same meaning as is commonly understood by one of skill in the art to which the claimed subject matter belongs. It is to be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of any subject matter claimed. In this application, the use of the singular includes the plural unless specifically stated otherwise. It must be noted that, as used in the specification and the appended claims, the singular forms "a," "an" and "the" include plural referents unless the context clearly dictates otherwise. In this application, the use of "or" means "and/or" unless stated otherwise. Furthermore, use of the term "including" as well as other forms, such as "include", "includes," and "included," is not limiting.

[0187] As used herein, ranges and amounts can be expressed as "about" a particular value or range. About also includes the exact amount. Hence "about 5 μΙ/' means "about 5 μΙ/' and also "5 μΚ" Generally, the term "about" includes an amount that would be expected to be within experimental error.

[0188] The section headings used herein are for organizational purposes only and are not to be construed as limiting the subject matter described.

[0189] As used herein, the terms "individual(s)", "subject(s)" and "patient(s)" mean any mammal. In some embodiments, the mammal is a human. In some embodiments, the mammal is a non-human. None of the terms require or are limited to situations characterized by the supervision (e.g. constant or intermittent) of a health care worker (e.g. a doctor, a registered nurse, a nurse practitioner, a physician's assistant, an orderly or a hospice worker).

[0190] A "site" corresponds to a single site, which in some cases is a single base position or a group of correlated base positions, e.g., a CpG site. A "locus" corresponds to a region that includes multiple sites. In some instances, a locus includes one site.

EXAMPLES

[0191] These examples are provided for illustrative purposes only and not to limit the scope of the claims provided herein. EXAMPLE 1

[0192] Table 1 illustrates top 100 eg markers per cancer type, subdivided based on tissue comparison categories. Table 1 is included at the end of the Examples section.

[0193] Table 2 illustrates exemplary 20 eg makers per cancer type.

17-25619946 cg07564598 7-127984393 cg08309135

2-219256101 eg 16926316 15-39472102 cgl3182816

CHOL Marker CpG COAD Marker CpG

6-32547019 cg07984380 2-29338432 cg08808128

1-198904195 cg09517106 2-66803033 cg02764245

5-174150712 cg26092471 15-28351906 cg04803843

12-108733275 cgl2142354 4-55991782 cg07893544

1-113498106 cgl2551029 1-76080727

12-102872937 cgl l612617 5-38556435 cgl2587766

6-27782628 cg05444312 20-61051039 cgl4980983

3-120627406 cg05293820 7-14941 1652 cg08131 100

6-27840105 cg05511483 20-34894648

2-158114424 15-28352098 cg03061682

Hypermethylated Hypermethylated

2-136743460 cgl8110444 20-61051032 cg20265733

6-32522683 cg25140213 12-45444895

6-27782484 eg 16347724 8-97506675 cg04261408

1-113497932 eg 16251079 1-1 15880865 cg09008705

3-157824209 cg l4961949 6-127440000 cgl9365062

4-147443095 cg20910303 9-707166 cgl4399863

1-113498174 eg 17020695 9-707387 cgl3877502

5-111115809 cgl l657018 4-55991860 cg00989765

1-113497999 cg07423363 4-157997554 egl 1163620

12-4381788 cgl5993083 1-57889035

13-111553101 cg23052386 19-39306244 eg 12028674

1-23418405 cgl5897613 3-150238257 cg02504622

6-36237037 cg27319730 10-518370 cg26718707

7-1946447 cg25786640 20-57616191 cg20726575

6-105854768 cgl 8879177 4-187629336 cg24820270

1-1 17489843 cg23093116 4-187629387 cg25352342

13-101241430 4-187629328 cg21399040

3-24213704 cg25087352 17-48845009 cg25518968

1-202559755 egl 1143857 7-150069026 eg 17677524

20-36033352 eg 14637027 4-6945745 cgl6574807

Hypomethylated Hypomethylated

10-5542941 cg26552733 5-179393917 cg26722544

6-34231501 cgl5495717 2-106959257 cg24419520

11-134118834 cg22756211 17-80535428 cg03454705

6-16147669 eg 15404791 1-1095607 cg02971920

10-135097477 cg27633010 2-8850020 cg00240378

10-76801843 cg23077498 7-73408058 cgl6233515

15-102261251 cgl4588686 11-2287734 eg 14907310

14-65210900 egl 1849213 7-73408101 eg 18780627

10-119101310 cg l7182036 2-106959384 cgl3656404

11-126072352 cg26351663 2-112808038 cg25890678

ESCA Marker CpG GBM Marker CpG

19-57078765 6-43237330 cg23514619

Hypermethylated Hypermethylated

19-56915732 19-19336240 cg25814383 19-56915650 17-55938871 cg22451358

19-56915658 12-57504948 cg01063813

19-56915655 19-1468943 cgl0565187

19-56915653 6-43237511 cg20434586

7-37960873 4-81123613 cg22054918

19-57078780 19-35531817 cg24139898

19-12175935 14-70038925 cg02380334

19-57078783 6-74233510 cg09681335

19-53696642 17-55938748 cg00023001

19-12175631 19-35531859 cg21484586

15-48470516 19-7937107 cg00438215

19-40315143 cg00498691 1-27894955 cgl2610832

7-37960317 11-65314161

7-37960731 19-2614086 cgl9250790

2-80531483 1-26690537 cgl2813724

12-94543449 16-744328 cg05542681

14-60097247 16-4233246 cg05006755

19-53696649 cgO 1620580 2-58273552 eg 18998670

1-1563500 cg09159050 12-131452297 cg23617848

5-131725325 cg23475112 1-10240017 cg27508545

X-2836027 7-4747216 cg01275887

7-157204364 eg 18362281 2-30041338 cg00073794

7-112431576 cg04876978 18-42325086 cg07015525

1-19280186 eg 11697440 4-146804010 cg01578875

19-57105832 cgl9641839 7-101849120 cg06010390

7-63772811 1-10240025 cg23661000

9-139913436 4-3372206

1-156232301 cgl0199857 1-6390793 cg00081799

Hypomethylated Hypomethylated

19-57082536 6-24140899 cg08908855

5-138032270 7-4747261 cg07076109

21-44195410 16-50897271 cg00900231

16-84446919 cg00838040 5-140865433 egl 1830096

11-47213196 cg05584439 10-405225 cg20595750

8-19026658 17-76220929 cg07366188

6-163730283 cgl0584587 17-63535223 cg06405341

1-228362509 eg 18277682 22-42611379 cg26799416

9-139907691 cgl4173587 8-9537322 eg 10419849

1-43971496 cg25211006 18-42324965 cg03722909

KICH Marker CpG KIRC Marker CpG

1-184357556 eg 10061342 13-113623844 cg09678836

16-4103492 cgl0177032 5-66299786 cg02632185

15-70767570 cgl6973527 5-66300503 cg27116842

Hypermethylated 4-74570525 cg23099587 Hypermethylated 13-113623639 cg00127894

5-43772975 13-113623659 cgl5179805

X-78201182 5-66300406 eg 17449851

7-28726216 cg05083033 5-66300433 cgl l831286 X-107020894 12-54427636 cgl6983211

1-9224198 cg22373770 12-52214119 cgl9495013

15-96957617 13-1 13623300 cgl6737670

16-474271 cg09555736 12-54422350 cg27441225

10-34320548 eg 10772185 8-107669856 cgl7176732

6-168134760 cg01797450 5-66299875 cgl8118497

16-30347333 8-107669783 cgl7136799

10-17273187 cg26063719 13-113623233 cg02223067

12-10022688 cgl2591315 8-107669787 cg26622232

6-166970727 egl 1387340 17-18908235 cgl4807365

16-15766942 2-73151879 cg00486564

16-474430 cg02102075 12-54427700 cgl5700739

11-7728814 cgl3563074 12-54422488 cg22378817

4-185362534 cg02354388 13-96086098 cg20278383

16-87873837 cg06665333 2-239169591

22-35694370 cg27436324 8-30209391 cgl4895559

8-6616240 cg24485696 16-81565917 cg03212183

20-57471672 13-1 1 1880998 cg21980364

11-66494177 cg22015277 4-87993109 cg27000934

5-173307471 cgl3384849 16-15127193 cg06978461

20-57471660 1-217724849 cgl0325088

4-38006787 cg23289854 20-6025272 cg21209310

17-81045501 cgl4521546 7-101556684 eg 15600935

Hypomethylated Hypomethylated

16-479994 eg 10357909 17-78700928 cg06975080

10-126314680 cg04426802 11-64323816 cg21039563

7-98667581 cg09221667 17-18855313 cg00306284

7-76871793 3-149051 159 cgl l011913

3-196693809 cg21429725 14-89628141 cg02212698

19-45316509 cg21978694 15-39958882

7-23723014 cg20200811 17-40064155 cg03950716

19-45316493 eg 12249345 1-101094117 cg00902464

14-95585023 cg23488578 7-101566857 cg02307880

13-33768013 5-111017556 cg01885839

LIHC Marker CpG LUAD Marker CpG

2-264178 cg20749741 6-152623304 cg05917732

1-145395753 cg l7952661 10-8092165 cgl5803869

19-54369556 6-152623479 eg 12023625

3-183543564 cgl9155007 1-23668691 cg00907427

2-264199 cg00108164 10-119304102

19-50096610 cgl5032314 1-23668792 cg08718097

Hypermethylated Hypermethylated

6-43044771 cg21663580 21-40984780 cg08448665

1-145395846 cg02395363 10-1 19304104 eg 12894449

6-56819429 7-2271722 cg03694580

3-183543587 cg09738156 21-40984777 cgl7900854

19-54369576 cg23305567 11-31832246 cg26848086

2-233792394 cg08165971 17-701 19120 cg21126344 2-264204 cg25945732 10-8096370 cgl5187550

19-6740952 cg03705926 21-40984886 cg03701992

5-176831297 eg 14126493 1-166134346

1 1-75917844 cgl7583449 1 1-31832353 cg05840031

5-176831638 cg05876864 10-8092264 eg 16710894

1-160370208 cgl3428480 6-50680997 cgl7489695

2-264164 cg03468349 10-8091753 cg22783180

1-21616619 eg 17216478 6-152623387 cg02682457

22-50644755 cg25934700 7-2473529 cgl7907628

5-16794882 cgl2852139 7-2473859 eg 18259487

15-99427016 cg03310087 5-141722174 cg02084814

10-1334207 cg04992974 10-1120831

16-87970367 cg05640992 6-25726912 cg07077277

1 1-46741373 cg26453360 16-3139060 cg20364187

7-1 1971 13 cg03923535 2-2321 13244 cg27273946

12-69199037 eg 10635494 14-74957673

8-142263802 cg00971369 6-25727291

11-6462110 eg 14164596 14-91691190 eg 14304073

Hypomethylated Hypomethylated

5-17275783 cgO 1860297 13-113445870

16-87970376 cg03550864 6-25727107

7-20269648 cgl90861 10 13-98869844 cgl6689193

1-167882440 cg24461337 14-91691 129 eg 16996571

2-44065725 cg20926720 4-37962455

7-4012372 cg04609841 6-25726953

1 1-102638470 cg03367136 10-52156632

17-26694939 cgl8536123 6-25726956

10-93390347 cg24288527 1-207975699

22-21128411 cg09634469 16-3641320

LUSC Marker CpG OV Marker CpG

Hypermethylated 19-10406145 cg23936587 19-58281450 eg 14038484

2-132348705 eg l 1467141 19-58281016 eg 18575209

15-73889528 cg06332339 19-58280832 cg03584535

2-239970152 cg08781549 19-58281117 cg22956410

2-239970075 cg26126749 19-58280927 cgl3636880

1-183204836 eg 14420230 19-58280891 cg07685728

12-21547892 cgl4191244 19-58280801 cg27046034

12-63195796 cg27185063 19-58281019 cg20751795

1-183204789 cg22684969 Hypermethylated 19-58280994 cg24298255

Hypomethylated

5-14160853 1 1-133582402 eg l 1368617

15-73889561 cg08435157 12-130529951 cgl6236851

3-185704206 cg09562655 10-95327305 cg05613447

12-11286360 cg24741148 10-95327292 eg 10905401

12-132643897 cgl6860971 10-74870311 cg01701415

12-93101181 cgl7344080 17-36104218

7-148481030 cg25477176 8-54569668 cg05483021

22-30572326 cg2421 1826 10-74870240 cg05898953 19-5789699 cg22961623 1-205399945 cg06849719

7-101603335 cg05855116 13-110899996 eg 15416440

1-64992433 1-205400197 cg06968878

15-73524906 cg08177743

PAAD Marker CpG PRAD Marker CpG

14-105715025 cg01237565 19-51416098 cgl7355294

16-1202468 eg 16427096 11-58940866 cg05415131

14-105714843 cgl6561543 19-16187631 eg 16232979

14-105714589 cg23034818 6-146136749 cg09094393

20-55204593 cgl2521353 7-32981826 cg08946731

10-11059577 cg23858040 10-74020976 cgl2799885

13-32605406 cg22219254 2-191045309 cg08350814

13-32605611 cgl6941656 7-120628874 cg01029638

2-177053345 cgl9001226 5-43193681 cgl0641714

4-141293985 19-16187889 cg26149167

Hypermethylated Hypermethylated

16-86231948 cg07989221 9-27529339 cg21244846

5-172756558 eg 16443866 15-35014270 cg24922143

5-172756550 cg08711858 17-46830260 cgl3132370

1-182584341 cg00153856 12-89744701 cg05769889

14-105714833 cgl5474367 19-51416517 cg20115266

11-61276678 6-146136563 cg23095615

4-141294009 10-111767379 cg05098590

22-17849639 cg26796679 1-116711077 eg 17933722

9-126773879 cgl0755973 2-191045668 cgl5313226

2-107503672 1-33938224 cgl8085998

SKCM Marker CpG UCEC Marker CpG

7-5468436 17-42092403 cg06511389

2-166650606 17-42092315 cg27116819

11-19798742 17-42092187 cgl8801599

17-77815779 19-50836561 cg01017355

6-10419927 17-42092370 cg08372947

11-441986 17-42092247 cg24638647

12-112204829 17-42092450 cgl3847066

14-61188431 18-5238310 cg20757519

12-48398374 cgl7054969 17-42091909 cg04879755

6-1311342 18-5238589 cgl0885961

Hypermethylated Hypermethylated

10-25241427 18-5238219 cgl5258847

6-10420079 17-42092488 cg25868286

1-111747228 17-42092472 cg01635193

6-26332204 3-169482895 cgl5494117

21-38630728 6-26045663 cg25438963

10-25241462 17-42092431 eg 12259256

7-5469535 19-50836910 cg03251287

11-19798914 3-169482358 cg27020690

1-6265894 3-10206731 eg 11029301

4-186732926 cg04392082 3-164914575 normal blood Marker CpG

3-188012918 cg02524983

1-43814358 cgl8856478

22-51136325 eg 18982286

12-58129855 eg 16402452

19-15568360 cg08846870

15-22798986

19-39086923 cg05258935

4-159969703 eg 10393744

16-67687754 cg09316954

11-57090226 egl 1180921

Hypermethylated

6-31510729

10-17391003 cg05576619

1-3135712

2-30737741

1-221613658 cg24686918

1-164581169 cg20812370

10-63809073 cgl4789659

17-43318735

6-12718370

5-10551547 cg24100671

[0194] Table 3 illustrates cancer name and its respective abbreviation.

KICH Kidney Chromophobe THCA Thyroid carcinoma

KIRC Kidney renal clear cell carcinoma UCS Uterine Carcinosarcoma

Kidney renal papillary cell Uterine Corpus Endometrial

KIRP UCEC

carcinoma Carcinoma

LIHC Liver hepatocellular carcinoma UVM Uveal Melanoma

LUAD Lung adenocarcinoma

[0195] Fig. 1 illustrates the methylation status of marker 7-1577016. In some instances, marker 7-1577016 is hypomethylated. In some cases, marker 7-1577016 is used as a pan cancer marker.

[0196] Fig. 2 illustrates the methylation status of marker 11 -67177103. In some cases, marker

11- 67177103 is used as a pan cancer marker.

[0197] Fig. 3 illustrates the methylation status of marker 19-10445516 (cgl7126555). In some cases, marker 19-10445516 (cgl7126555) is used as a pan cancer marker.

[0198] Fig. 4 illustrates the methylation status of marker 12-122277360. In some cases, marker

12- 122277360 is used as a liver cancer diagnostic marker.

[0199] Fig. 5 illustrates the methylation status of marker 6-72130742 (cg24772267). In some cases, marker 6-72130742 (cg24772267) is used as a colon cancer diagnostic marker.

[0200] Fig. 6 illustrates the methylation status of marker 3-15369681. In some cases, marker 3- 15369681 is used as a liver cancer diagnostic marker.

[0201] Fig. 7 illustrates the methylation status of marker 3-131081177. In some cases, marker 3-131081177 is used as a breast cancer diagnostic marker.

EXAMPLE 2 - Generating a reference eg marker panel

[0202] Data sources

[0203] DNA methylation data from initial training set and first testing set were obtained from

The Cancer Genome Atlas (TCGA).

[0204] Generating a reference eg marker set

[0205] Cancer type specific signature was identified by comparing the pair-wise methylation difference between a particular cancer type versus its corresponding normal tissue, the difference between two different cancer types, as well as difference between two different normal tissues, with a total of 12 tissue groups including 6 tumor groups and 6 normal tissue groups. Patient samples were randomly divided from the TCGA representing 9 cancer types from 6 different tissues with matched adjacent-normal tissue into training and validation cohorts. To do this, a total of 12 * 11 / 2 = 66 unique pair- wise comparisons were performed. Using an Illumina 450,000 CpG methylation microarray, 450k markers were compared from one group to another group using the [column t test] colttests() function in the R genefilter package. Markers with the lowest p values by t-statistic and the largest difference in a mean methylation fraction between each comparison were ranked and the top ten markers in each group were selected for further validation analysis.

[0206] Calculate weights for top ten markers in each comparison

[0207] The Principle Component analysis was applied to the top ten markers in each comparison group using the function in the stats environment: prcomp() and the weights in the first principle component of each group were extracted and matched with the ten corresponding markers in each group. There were 45 groupings of weights with markers. These markers were used to classify the samples with several algorithms including Neural Networks, Logistic Regression, Nearest Neighbor (NN) and Support Vector Machines (SVM), all of which generated consistent results. Analyses using SVM were found to be most robust and were therefore used in all subsequent analyses.

[0208] For each tumor type, samples were divided into two groups based on the resulting methylation signatures and their survival was plotted using Kaplan-Meier curves. Subgroups based on tumor stage and the presence of residual tumor following treatment was also analyzed. These methylation profiles were able to predict highly statistically significant differences in survival in all tumor types and most subgroups examined.

[0209] Generate Variables

[0210] 45 variables for each of the samples in the data were generated. Using the

weight/marker combination, each variable V was calculated using the following equation:

[0211] where W is the weight and M is the methylation Beta-value between 0 and 1 of the corresponding marker. A matrix was generated where the dimensions are (1) the number of samples by (2) 190 variables.

[0212] Classifying Samples

[0213] The above mentioned matrix was used to classify the samples. There are several classification algorithms that were used here including Logistic Regression, Nearest Neighbor (NN) and Support Vector Machines (SVM). Analysis using SVM were used in all subsequent analyses.

[0214] The Kernel-Based Machine Learning Lab (kernlab) library for R was used to generate the Support Vector Machines. The best results were with the "RBF" kernel. The Crammer, Singer algorithm had slightly better results than the Weston, Watson algorithm. In the analysis, four potential types of classification errors were seen.

1. Incorrect Tissue; e.g. colon tissue is identified as lung tissue.

2. False negative; e.g. lung cancer is identified as normal lung 3. False positive; e.g. normal colon is identified as colon cancer

4. Correct tissue, incorrect cancer type; e.g. kidney renal clear cell carcinoma is identified as kidney renal papillary cell carcinoma.

[0215] Three methods were used to validate the results:

1. The samples were divided into five equal parts and 4 of the parts were used for training and the fifth part was used to test the results.

2. Leave one out scenario was used where all of the samples were used for training except one. The one left out was used for testing. This was repeated for each sample until they had all been tested.

3. Two stage replication study: The samples were divided into two sets at the beginning of the process. With the training set, 10 markers in each comparison with the highest t-test scores were identified. These markers were then used to generate principal components and then used these variables to create a SVM. The obtained markers were applied to the test set, and principal components and SVM results were generated.

[0216] Tumor DNA extraction

[0217] Genomic DNA extraction from pieces of freshly frozen healthy or cancer tissues was performed with QIAamp DNA Mini Kit (Qiagen) according to manufacturer's recommendations. Roughly 0.5 mg of tissue was used to obtain on average 5 μg of genomic DNA. DNA was stored at -20°C and analyzed within one week of preparation.

[0218] DNA extraction from FFPE samples

[0219] Genomic DNA from frozen FFPE samples was extracted using QIAamp DNA FFPE Tissue Kit with several modifications. DNA was stored at -20°C for further analysis.

[0220] Bisulfite conversion of genomic DNA

[0221] 1 μg of genomic DNA was converted to bis-DNA using EZ DNA Methylation- Lightning™ Kit (Zymo Research) according to the manufacturer's protocol. Resulting bis-DNA had a size distribution of -200-3000 bp, with a peak around -500-1000 bp. The efficiency of bisulfite conversion was >99.8% as verified by deep-sequencing of bis-DNA and analyzing the ratio of C to T conversion of CH (non-CG) dinucleotides.

[0222] Padlock Probe Designs

[0223] CpG markers whose methylation levels significantly differed in any of the comparison between a cancer tissue and normal tissue were used to design padlock probes for sequencing.

[0224] Padlock probes were designed using the ppDesigner software. The average length of the captured region was 70 bp, with the CpG marker located in the central portion of the captured region. To prevent bias introduced by unknown methylation status of CpG markers, capturing arms were positioned exclusively within sequences devoid of CG dinucleotides. Linker sequence between arms contained binding sequences for amplification primers separated by a variable stretch of Cs to produce probes of equal length. The average length of probes was 91 bp. Probes incorporated a 6-bp unique molecular identifier (UMI) sequence to allow for the identification of individual molecular capture events and accurate scoring of DNA methylation levels.

[0225] Probes were synthesized as separate oligonucleotides using standard commercial synthesis methods. For capture experiments, probes were mixed, in-vitro phosphorylated with T4 PNK (NEB) according to manufacturer's recommendations and purified using P-30 Micro Bio- Spin columns (Bio-Rad).

[0226] Bis-DNA capture

[0227] 20 ng of bisulfite-converted DNA was mixed with a defined molar ratio of padlock probes in 20 μΐ reactions containing IX Ampligase buffer (Epicentre). The optimal molar ratio of probes to DNA was determined experimentally to be 20,000: 1. Reactions were covered with 50μ1 of mineral oil to prevent evaporation. To anneal probes to DNA, 30 second denaturation at 95°C was followed by a slow cooling to 55°C at a rate of 0.02°C per second. Hybridization was left to complete for 15hrs at 55°C. To fill gaps between annealed arms, 5μ1 of the following mixture was added to each reaction: 2U of PfuTurboCx polymerase (pre-activated for 3 min at 95°C

(Agilent)), 0.5U of Ampligase (Epicentre) and 250 pmol of each dNTP in IX Ampligase buffer. After 5 hour incubation at 55°C, reactions were denatured for 2 minutes at 94°C and snap -cooled on ice. 5 μΐ of exonuclease mix (20U of Exo I and 100U of ExoIII, both from Epicentre) was added and single-stranded DNA degradation was carried out at 37°C for 2 hours, followed by enzyme inactivation for 2 minutes at 94°C.

[0228] Circular products of site specific capture were amplified by PCR with concomitant barcoding of separate samples. Amplification was carried out using primers specific to linker DNA within padlock probes, one of which contained specific 6bp barcodes. Both primers contained Illumina next-generation sequencing adaptor sequences. PCR was done as follows: IX Phusion Flash Master Mix, 3 μΐ of captured DNA and 200nM final [c] of primers, using the following cycle: 10s @ 98°C, 8X of (Is @ 98°C, 5s @ 58°C, 10s @ 72°C), 25X of (Is @ 98°C, 15s @ 72°C), 60s @ 72°C. PCR reactions were mixed and the resulting library was size selected to include effective captures (~230bp) and exclude "empty" captures (~150bp) using Agencourt AMPure XP beads (Beckman Coulter). Purity of the libraries was verified by PCR using Illumina flowcell adaptor primers (P5 and P7) and the concentrations were determined using Qubit dsDNA HS assay (Thermo Fisher). Libraries were sequenced using MiSeq and HiSeq2500 systems (Illumina).

[0229] Optimization of capture coverage uniformity

[0230] Deep sequencing of the original pilot capture experiments showed significant differences between number of reads captured by most efficient probes and non-efficient probes (60-65% of captured regions with coverage >0.2 of average). To ameliorate this, relative efficiencies were calculated from sequencing data and probes were mixed at adjusted molar ratios. This increased capture uniformity to 85% of regions at > 0.2 of average coverage.

[0231] Sequencing data analysis

[0232] Mapping of sequencing reads was done using the software tool bisReadMapper (Diep, D, Nat Methods. 2012 Feb 5;9(3):270-272) with some modifications. First, UMI were extracted from each sequencing read and appended to read headers within FASTQ files using a custom script generously provided by D.D. Reads were on-the-fly converted as if all C were non- methylated and mapped to in-silico converted DNA strands of the human genome, also as if all C were non-methylated, using Bowtie2 (Langmead B, Salzberg S. Fast gapped-read alignment with Bowtie 2. Nature Methods. 2012, 9:357-359). Original reads were merged and filtered for single UMI, i.e. reads carrying the same UMI were discarded leaving a single one. Methylation frequencies were extracted for all CpG markers for which padlock probes were designed.

Markers with less than 20 reads in any sample were excluded from analysis.

EXAMPLE 3 - Generating a eg marker panel for diagnosis and prognosis of hepatocellular carcinoma from cfDNA

[0233] Patient data

[0234] Tissue DNA methylation data was obtained from The Cancer Genome Atlas (TCGA). Complete clinical, molecular, and histopathological datasets are available at the TCGA website. Individual institutions that contributed samples coordinated the consent process and obtained informed written consent from each patient in accordance to their respective institutional review boards.

[0235] A second independent Chinese cohort consisted of HCC patients at the Sun Yat-sen University Cancer Center in Guangzhou, Xijing Hospital in Xi'an and the West China Hospital in Chengdu, China. Those who presented with HCC from stage I-IV were selected and enrolled in this study. Patient characteristics and tumor features are summarized in Supplementary Table 1. The TNM staging classification for HCC is according to the 7th edition of the AJCC cancer staging manual . The TNM Staging System is one of the most commonly used tumor staging systems. This system was developed and is maintained by the American Joint Committee on Cancer (AJCC) and adopted by the Union for International Cancer Control (UICC). The TNM classification system was developed as a tool for oncologists to stage different types of cancer based on certain standard criteria. The TNM Staging System is based on the extent of the tumor (T), the extent of spread to the lymph nodes (N), and the presence of metastasis (M). This project was approved by the IRBs of Sun Yat-sen University Cancer Center, Xijing Hospital, and West China Hospital. Informed consent was obtained from all patients. Tumor and normal tissues were obtained as clinically indicated for patient care and were retained for this study. Human blood samples were collected by venipuncture and plasma samples were obtained by taking supernatant after centrifugation and stored at -80°C before cfDNA extraction. The key raw data were verified and uploaded onto the Research Data Deposit public platform with an approval number

RDDB2017000132.

[0236] Tumor DNA extraction

[0237] Genomic DNA extraction from freshly frozen healthy or cancer tissues was performed with QIAamp DNA Mini Kit (Qiagen) according to manufacturer's recommendations. Roughly 0.5 mg of tissue was used to obtain on average 5 μg of genomic DNA. DNA was stored at -20°C and analyzed within one week of preparation.

[0238] DNA extraction from FFPE samples

[0239] Genomic DNA from frozen FFPE samples was extracted using QIAamp DNA FFPE Tissue Kit with several modifications. DNA were stored at -20°C for further analysis.

[0240] Cell-free DNA extraction from plasma samples

[0241] cfDNA extraction from 1.5 ml of plasma samples was performed with QIAamp cfDNA Kit (Qiagen) according to manufacturer's recommendations.

[0242] Bisulfite conversion of genomic DNA

[0243] About 10 ng of cf DNA was converted to bis-DNA using EZ DNA Methylation- Lightning™ Kit (Zymo Research) according to the manufacturer's protocol. Resulting bis-DNA had a size distribution of -200-3000 bp, with a peak around -500-1000 bp. The efficiency of bisulfite conversion was >99.8% as verified by deep-sequencing of bis-DNA and analyzing the ratio of C to T conversion of CH (non-CG) dinucleotides.

[0244] Determination of DNA methylation levels by deep sequencing of bis-DNA captured with molecular-inversion (padlock) probes

[0245] CpG markers whose methylation levels significantly differed in any of the comparisons between any cancer tissue and any normal tissue were used to design padlock probes for capture and sequencing of cfDNA. Padlock-capture of bis-DNA was based on the technique on published methods with modifications.

[0246] Probe design and synthesis

[0247] Padlock probes were designed using the ppDesigner software. The average length of the captured region was 100 bp, with the CpG marker located in the central portion of the captured region. Linker sequence between arms contained binding sequences for amplification primers separated by a variable stretch of Cs to produced probes of equal length. A 6-bp unique molecular identifier (UMI) sequence was incorporated in probe design to allow for the identification of unique individual molecular capture events and accurate scoring of DNA methylation levels. [0248] Probes were synthesized as separate oligonucleotides using standard commercial synthesis methods (ITD). For capture experiments, probes were mixed, in-vitro phosphorylated with T4 PNK (NEB) according to manufacturer's recommendations and purified using P-30 Micro Bio-Spin columns (Bio-Rad).

[0249] Bis-DNA capture

[0250] About 10 ng of bisulfite-converted DNA was mixed with padlock probes in 20 μΐ reactions containing IX Ampligase buffer (Epicentre). To anneal probes to DNA, 30 second denaturation at 95°C was followed by a slow cooling to 55°C at a rate of 0.02°C per second. Hybridization was left to complete for 15 hrs at 55°C. To fill gaps between annealed arms, 5μ1 of the following mixture was added to each reaction: 2U of PfuTurboCx polymerase (Agilent), 0.5U of Ampligase (Epicentre) and 250 pmol of each dNTP in IX Ampligase buffer. After 5 hour incubation at 55°C, reactions were denatured for 2 minutes at 94°C. 5 μΐ of exonuclease mix (20U of Exo I and 100U of ΕχοΠΙ, both from Epicentre) was added and single-stranded DNA degradation was carried out at 37°C for 2 hours, followed by enzyme inactivation for 2 minutes at 94°C.

[0251] Circular products of site-specific capture were amplified by PCR with concomitant barcoding of separate samples. Amplification was carried out using primers specific to linker DNA within padlock probes, one of which contained specific 6bp barcodes. Both primers contained Illumina next-generation sequencing adaptor sequences. PCR was done as follows: IX Phusion Flash Master Mix, 3 μΐ of captured DNA and 200nM primers, using the following cycle: 10s @ 98°C, 8X of (Is @ 98°C, 5s @ 58°C, 10s @ 72°C), 25X of (Is @ 98°C, 15s @ 72°C), 60s @ 72°C. PCR reactions were mixed and the resulting library was size selected to include effective captures (~230bp) and exclude "empty" captures (~150bp) using Agencourt AMPure XP beads (Beckman Coulter). Purity of the libraries was verified by PCR using Illumina flowcell adaptor primers (P5 and P7) and the concentrations were determined using Qubit dsDNA HS assay (Thermo Fisher). Libraries were sequenced using MiSeq and HiSeq2500 systems (Illumina).

[0252] Optimization of capture coverage uniformity

[0253] Deep sequencing of the original pilot capture experiments showed significant differences between number of reads captured by most efficient probes and non-efficient probes (60-65% of captured regions with coverage >0.2x of average). To ameliorate this, relative efficiencies were calculated from sequencing data and probes were mixed at adjusted molar ratios. This increased capture uniformity to 85% of regions at > 0.2x of average coverage.

[0254] Sequencing data analysis

[0255] Mapping of sequencing reads was done using the software tool bisReadMapper with some modifications. First, UMI were extracted from each sequencing read and appended to read headers within FASTQ files using a custom script. Reads were on-the-fly converted as if all C were non-methylated and mapped to in-silico converted DNA strands of the human genome, also as if all C were non -methylated, using Bowtie2[28]. Original reads were merged and filtered for single UMI, i.e. reads carrying the same UMI were discarded leaving a single, unique read. Methylation frequencies were calculated for all CpG dinucleotides contained within the regions captured by padlock probes by dividing the numbers of unique reads carrying a C at the interrogated position by the total number of reads covering the interrogated position.

[0256] Identification of Blocks of Correlated Methylation (BCM)

[0257] Pearson correlation coefficients between methylation frequencies of each pair of CpG markers separated by no more than 200bp were calculated separately across 50 cfDNA samples from each of the two diagnostic categories, ie normal health blood and HCC. A value of Pearson's r<0.5 was used to identify transition spots (boundaries) between any two adjacent markers indicating uncorrelated methylation. Markers not separated by a boundary were combined into Blocks of Correlated Methylation (BCM). This procedure identified a total of -1550 BCM in each diagnostic category within our padlock data, combining between 2 and 22 CpG positions in each block. Methylation frequencies for entire BCMs were calculated by summing up the numbers of Cs at all interrogated CpG positions within a BCM and dividing by the total number of C+Ts at those positions.

[0258] DNA isolation and digital Quantitative PCR

[0259] Tumor and corresponding plasma samples were obtained from patients undergoing surgical tumor resection; samples were frozen and preserved in at -80°C until use. Isolation of DNA and RNA from samples was performed using AllPrep DNA/RNA Mini kit and a cfDNA extraction kit, respectively (Qiagen, Valencia, CA).

[0260] Data sources

[0261] DNA methylation data of 485,000 sites generated using the Infinium 450K Methylation Array were obtained from the TCGA and dataset generated from our previous study (GSE40279) in which DNA methylation profiles for HCC and blood were analyzed. ID AT format files of the methylation data were generated containing the ratio values of each scanned bead. Using the minfi package from Bioconductor, these data files were converted into a score, referred to as a Beta value. Methylation values of the Chinese cohort were obtained by targeted bisulfate sequencing using a molecular inversion probe and analyzed as described below.

[0262] Statistical Analysis—DNA methylation marker pre-selection for diagnostic and prognostic analysis

[0263] A differential methylation analysis on TCGA data using a "moderated t-statistics shrinking" approach was first performed and the P-value for each marker was then corrected by multiple testing by the Benjamini-Hochberg procedure to control FDR at a significance level of 0.05. The list was ranked by adjusted P-value and selected the top 1000 markers for designing padlock probes. cfDNA samples with low quality or fewer than 20,000 reads per sample were also eliminated. Methylation values for each marker were defined as the proportion of read counts with methylation divided by total read counts. Methylation markers with a range of methylation values less than 0.1 in matched tumor tissue and tumor blood samples were eliminated.

[0264] Building a eg marker panel from cfDNA

[0265] The cfDNA dataset was randomly split into training and validation cohorts with a 2: 1 ratio. Two variable selection methods suitable for high-dimensionality on the prescreened training dataset were applied: Least Absolute Shrinkage and Selection Operator (LASSO) and Random Forest based variable selection method using OOB error. As results can depend strongly on the arbitrary choice of a random sample split for sparse high-dimensional data, an analysis of the "multi-split" method were adopted, which improves variable selection consistency while controlling finite sample error. For LASSO selection operator, 75 percent of the dataset was subsampled without replacement 500 times and selected the markers with repeat occurrence frequency more than 450. The tuning parameters was determined according to the expected generalization error estimated from 10-fold cross-validation and information -based criteria AIC/BIC, and the largest value of lambda was adopted such that the error was within one standard error of the minimum, known as "1-se" lambda. For the random forest analysis, using the OOB error as a minimization criterion, variable elimination from the random forest was carried out by setting variable a dropping fraction of each iteration at 0.3. Ten overlapping methylation markers were chosen by the two methods for model building a binary prediction. A logistic regression model was fitted using these 10 markers as the covariates and obtained a combined diagnosis score (designated as cd-score) by multiplying the unbiased coefficient estimates and the marker methylation value matrix in both the training and validation datasets. The predictability of the model was evaluated by area under ROC (AUC, also known as C-index), which calculated the proportions of concordant pairs among all pairs of observations with 1.0 indicating a perfect prediction accuracy. Confusion tables were generated using an optimized cd- score cutoff with a maximum Youden's index.

[0266] The pre-treatment or initial methylation level was evaluated at baseline, and the post- methylation level was evaluated approximately 2 months after treatment, where the treatment referred to either chemotherapy or surgical resection of tumor. The primary endpoint (including response to treatment: progressive disease (PD), partial response (PR) and stable disease (SD)) were defined according to the RECIST guideline. For patients treated with surgical removal and no recurrence at time of evaluation, it was assumed that they had complete response (CR). The difference of cd-score distribution between clinical categories was examined by Wilcoxon Rank Sum test as cd-score was tested to be non-normally distributed using a Shapiro-Wilk Test.

[0267] Patient and sample characteristics [0268] Clinical characteristics and molecular profiling including methylation data for comparison between HCC and blood lymphocytes were assembled from sources including 377 HCC tumor samples from The Cancer Genome Atlas (TCGA) and 754 blood leukocyte samples of healthy control individuals from a dataset on aging (GSE40279). To study ctDNA in HCC, plasma samples were obtained from Chinese patients with HCC and randomly selected healthy controls undergoing routine health care maintenance, resulting in a training cohort of 715 HCC patients and 560 normal healthy controls and a validation cohort of 383 HCC patients and 275 healthy controls. All participants provided written informed consent.

[0269] Identification of methylation markers differentiating HCC and blood

[0270] It was hypothesized that CpG markers with a maximal difference in methylation between HCC and blood leukocytes in normal individuals would be most likely to demonstrate detectable methylation differences in the cfDNA of HCC patients when compared to that of normal controls. The "moderated t-statistics" method was used with Empirical Bayes for shrinking the variance, and the Benjamini-Hochberg procedure to control the FDR at a significance level of 0.05 to identify the top 1000 markers with the most significantly different rates of methylation (i.e. those with the lowest p-values) between HCC and blood. Unsupervised hierarchical clustering of these top 1000 markers was able to distinguish between HCC and blood leukocytes in normal individuals (Fig. 12). Molecular inversion (padlock) probes was designed corresponding to these 1000 markers and tested them in 28 pairs of HCC tissue DNA and matched plasma ctDNA from the same patient. The methylation profiles in HCC tumor DNA and matched plasma ctDNA were consistent (Fig. 9A, Fig. 9B). 401 markers with a good

experimental amplification profile and dynamic methylation range were selected for further analysis.

[0271] Methylation block structure for improved allele calling accuracy

[0272] The concept of genetic linkage disequilibrium (LD block) was employed to study the degree of co-methylation among different DNA strands, with the underlying assumption that DNA sites in close proximity are more likely to be co-methylated than distant sites. A paired-end Illumina sequencing reads was used to identify each individual methylation block (mBlock). A Pearson correlation method to quantify co-methylation or mBlock was used. All common mBlocks of a region were compiled by calculating different mBlock fractions. The genome was then partitioned into blocks of tightly co-methylated CpG sites termed methylation correlated blocks (MCBs), using an r ² cutoff of 0.5. MCBs was surveyed in cfDNA of 500 normal samples and found that MCBs are highly consistent. It was next determined methylation levels within an MCB in the cfDNA from 500 HCC samples. It was found that a highly consistent methylation pattern in MCBs when comparing normal versus HCC cfDNA samples, which significantly enhanced allele-calling accuracy (Fig. 13). This technique was employed in all subsequent sequencing analysis.

[0273] cfDNA diagnostic prediction for HCC

[0274] The methylation values of the 401 selected markers that showed good methylation ranges in cfDNA samples were analyzed by Random Forest and Least Absolute Shrinkage and Selection Operator (LASSO) methods to further reduce the number of markers by modeling them in 715 HCC ctDNA and 560 normal cfDNA samples (Fig. 8). 24 markers were obtained using the Random Forest analysis. 30 markers were obtained using a LASSO analysis in which selected markers were required to appear over 450 times out of a total of 500 repetitions. There were 10 overlapping markers between these two methods (Table 4). Using a logistic regression method, a diagnostic prediction model was constructed with these 10 markers. Applying the model yielded a sensitivity of 94.3% and specificity of 85.7% for HCC in the training dataset of 715 HCC and 560 normal samples (Fig. 9C) and a sensitivity of 90.5% and specificity of 83.2% in the validation dataset of 383 HCC and 275 normal samples (Fig. 9D). It was also demonstrated this model could differentiate HCC from normal controls both in the training dataset (AUC =0.966) and the validation dataset (AUC=0.944) (Fig. 9E, Fig. 9F). Unsupervised hierarchical clustering of these 10 markers was able to distinguish HCC from normal controls with high specificity and sensitivity (Fig. 9G, Fig. 10H, Fig. 14).

Table 4

SE: standard errors of coefficient; z value: Wald z-statistic value

[0275] It was next assessed that a combined diagnostic score (cd-score) of the model for differentiating between liver diseases (HBV/HCV infection, and fatty liver) and HCC, since these liver diseases are known major risk factors for HCC. It was found that the cd-score could differentiate HCC patients from those with liver diseases or healthy controls (Fig. 10A). These results were consistent and comparable with those predicted by AFP levels (Fig. 10B).

[0276] Methylation markers predicted tumor load, treatment response, and staging

[0277] It was next studied that the utility of the cd-score in assessing treatment response, the presence of residual tumor following treatment, and staging of HCC. Clinical and demographic characteristics, such as age, gender, race, and AJCC stage were included in the analysis. The cd- scores of patients with detectable residual tumor following treatment (n=828) were significantly higher than those with no detectable tumor (n=270), and both were significantly greater than normal controls (n=835) (p<0.0001, Fig. IOC). Similarly, cd-scores were significantly higher in patients before treatment (n=109) or with progression (n=381) compared to those with treatment response (n=248) (p< 0.0001, Fig. 10D). In addition, cd-scores were significantly lower in patients with complete tumor resection after surgery (n=170) compared with those before surgery (n=109), yet were higher in patients with recurrence (n=155) (p< 0.0001, Fig. 10E). Furthermore, there is good correlation between the cd-scores and tumor stage. Patients with early stage disease (I, II) had substantially lower cd-scores compared to those with advanced stage disease (III, IV) (p<0.05, Fig. 10F). Collectively, these results suggest that the cd-score (i.e., the amount of ctDNA in plasma) correlates well with tumor burden and may have utility in predicting tumor response and surveillance for recurrence.

[0278] Utility of ctDNA diagnostic prediction and AFP

[0279] In some instances, the blood biomarker for risk assessment and surveillance of HCC is serum AFP levels. However, its low sensitivity makes it inadequate to detect all patients that will develop HCC and severely limits its clinical utility. In fact, many cirrhotic patients develop HCC without any increase in AFP levels. Strikingly, 40% patients of the HCC study cohort have a normal serum AFP (<25 ng/ml).

[0280] In biopsy-proven HCC patients, the cd-score demonstrated superior sensitivity and specificity than AFP for HCC diagnosis (AUC 0.969 vs 0.816, Fig. 10G). In patients with treatment response, tumor recurrence, or progression, cd-score showed more significant changes compared to testing at initial diagnosis than AFP (Fig. 10H, Fig. 101). In patients with serial samples, those with a positive treatment response had a concomitant significant decrease in cd- score compared to that prior to treatment, and there was an even further decrease in patients after surgery. By contrast, our patients with progressive or recurrent disease all had an increase in cd- score (Fig. 15). By comparison, AFP was less sensitive for assessing treatment efficacy in individual patients (Fig. 16). In addition, while cd-score correlated well with tumor stage (Fig. 10 J), particularly among patients with stage I, II and III, there was no significant difference in AFP values in patients with different stages, except between patients with stage ΠΙ and IV (Fig. 10K), indicating an advantage of cd-score over AFP in differentiation of early stage HCC. [0281] ctDNA prognostic prediction for HCC

[0282] It was then investigated the potential of using methylation markers in ctDNA for prediction of prognosis in HCC in combination with clinical and demographic characteristics including age, gender, race, and AJCC stage. The 1049 HCC patients were randomly split with complete survival information into training and validation datasets with an allocation of 2: 1. Unicox and LASSO-cox methods were implemented to reduce the dimensionality and

constructed a cox-model to predict prognosis with an 8-marker panel (Table 5). Kaplan-Meier curves was generated in training and validation datasets using a combined prognosis score (cp- score) with these markers. The high-risk group (cp-score > -0.24) had 341 observations with 53 events in training dataset and 197 observations with 26 events in validation dataset; and the low- risk group (cp-score < -0.24) has 339 observations with 7 events in training dataset and 172 observations with 9 events in validation dataset. Median survival was significantly different in both the training set (/?<0.0001) and the validation set (p= 0.0014) by log-rank test (Fig. 11 A, Fig. 11B).

Table 5

HR: Hazard Ratio; CI: 95.0% confidence interval; SE: standard errors of coefficients; z value: Wald z-statistic value

[0283] Multivariate variable analysis showed that the cp-score was significantly correlated with risk of death both in the training and validation dataset and that the cp-score was an independent risk factor of survival (hazard ratio [HR]: 2.512; 95% confidence interval [CI]:

1.966-3.210; /?<0.001 in training set; HR: 1.553, CI: 1.240-1.944; /?<0.001 in validation set. Interestingly, AFP was no longer significant as a risk factor when cp-score and other clinical characteristics were taken into account. [0284] As expected, TNM stage predicted the prognosis of patients in the training and validation dataset (Fig. 11C, Fig. 1 ID). However, the combination of cp-score and TNM staging improved the ability to predict prognosis in both the training (AUC 0.7935, Fig. 1 IE) and validation datasets (AUC 0.7586, Fig. 1 IF). Kaplan-Meier curves also showed that patients separated by both cp-score and staging have different prognosis (/?<0.0001, Fig. 11G). These results demonstrate that ctDNA methylation analysis may contribute to risk stratification and prediction of prognosis in patients with HCC.

[0285] In this study, differentially methylated CpG sites were first determined between HCC tumor samples and blood leukocytes in normal individuals for an HCC-specific panel. A diagnostic prediction model then constructed was using a 10-methylation marker panel (cd-score) for use in cfDNA; the cd-score effectively discriminated patients with HCC from individuals with HBV/HCV infection, cirrhosis, and fatty liver as well as healthy controls. Given that patients with these liver diseases are the target screening population under current guidelines, it is important that a serum test reliably distinguish these disease states from HCC. In the study, the sensitivity of the cd-score for HCC is comparable to liver ultrasound, the current standard for HCC screening, markedly superior to AFP, and may represent a more cost-effective and less resource- intensive approach. Furthermore, the cd-score of the model showed high correlation with HCC tumor burden, treatment response, and stage, and is superior to the performance of AFP in the instant cohort. In some cases, the cd-score is useful for assessment of treatment response and surveillance for recurrence.

EXAMPLE 4 - Cell-free DNA methylation markers for diagnosis and prognosis of lung cancer and hepatocellular carcinoma

[0286] Primary tissue patient data

[0287] Both primary solid tissues from cancer patients and blood tissues from healthy donor were measured by Illumina 450k infimum bead chip. Primary tumor DNA methylation data of 485,000 sites was obtained from The Cancer Genome Atlas (TCGA). Complete clinical, molecular, and histopathological datasets are available at the TCGA website. Individual institutions that contributed samples coordinated the consent process and obtained informed written consent from each patient in accordance to their respective institutional review boards. Blood tissue DNA methylation data from healthy donor were obtained and generated based on study from Hannum et al, 2013, Mol Cell 49, 359-367 (GSE40279) in which DNA methylation profiles for HCC and blood were analyzed.

[0288] Serum sample patient data

[0289] A second independent Chinese cohort consisted of LUNC and HCC patients at the Sun Yat-sen University Cancer Center in Guangzhou, Xijing Hospital in Xi'an, and the West China Hospital in Chengdu, China. Patients who presented with LUNC and HCC from stage I-IV were selected and enrolled in this study. Patient characteristics and tumor features are summarized in Table 9. The TNM staging classification for LUNC and HCC is according to the 7 ^th edition of the AJCC cancer staging manual. This project was approved by the IRBs of Sun Yat-sen University Cancer Center, Xijing Hospital, and West China Hospital. Informed consent was obtained from all patients. Two prospective trials on early detection of LUNC and HCC patients using methylation markers for predicting cancer occurrence in high-risk populations were conducted. In the first study, patients were recruited from a group of smokers that were undergoing CT scan- based lung cancer screening from Dec 2015 to Dec 2016. Patients presenting with lung nodules (<10mm, n=232, Table 12) were selected to undergo methylation profiling at the time of screening and were subsequently followed through secondary testing to determine whether nodules were due to cancer or inflammatory or infectious conditions by tissue biopsy and pathology diagnosis verification. In the second trial, high risk patients with liver cirrhosis were enrolled (n=242).

[0290] Tumor and normal tissues were obtained as clinically indicated for patient care and were retained for this study. Human blood samples were collected by venipuncture, and plasma samples were obtained by taking the supernatant after centrifugation and stored at -80°C before cfDNA extraction.

[0291] The pre-treatment serum samples were obtained at the initial diagnosis, and the post- treatment serum samples were evaluated approximately 2 months after treatment, where the treatment referred to either chemotherapy or surgical resection of tumor. The primary endpoint (including response to treatment: progressive disease (PD), partial response (PR) and stable disease (SD)) was defined according to the RECIST guideline. For patients treated with surgical removal and no recurrence at time of evaluation, it was assumed that they had complete response (CR).

[0292] Extraction of cfDNA from plasma

[0293] It was determined that the minimal volume of plasma required to get consistent amounts of cfDNA for targeted sequencing. As a rough guide, it was aimed at ~20X coverage at 90% of markers covered by the padlock probe panel (see below). It was observed that 20,000 or more total unique reads per sample fulfilled this criterion. It was found that 1.5 ml or more plasma could reliably yield enough cfDNA to produce >20,000 unique reads. The relationship between amount of cfDNA in 1.5 ml plasma and detected copy numbers was further investigated using digital droplet PCR. It was found that 1.5ml of plasma yielded > lOng, what produced at least 140 copies of detected amplicons in each digital droplet PCR assay. It was therefore settled on using 15 ng/1.5 ml as a cutoff in all of our experiments to obtain consistent and reliable measurements of DNA methylation. [0294] cfDNA from 1.5ml of plasma was extracted using EliteHealth cfDNA extraction Kit (EliteHealth, Guangzhou Youze, China) according to manufacturer's recommendations.

[0295] Bisulfite conversion of genomic or cfDNA

[0296] 10 ng of DNA was converted to bis-DNA using EZ DNA Methylation-Lightning™ Kit (Zymo Research) according to the manufacturer's protocol. Resulting bis-DNA had a size distribution of -200-3000 bp, with a peak around -500-1000 bp. The efficiency of bisulfite conversion was >99.8% as verified by deep-sequencing of bis-DNA and analyzing the ratio of C to T conversion of CH (non-CG) dinucleotides.

[0297] Marker selection for padlock probe panel design

[0298] To identify markers to differentiate HCC, LUNC and normal blood methylation signatures the "moderated t-statistics shrinking" approach on 450k methylation data with Benjamini-Hochberg procedure was employed to control FDR at a significance level of 0.05 using pairwise comparisons of 377 HCC samples and 827 LUNC samples (TCGA) and 754 normal blood samples (GSE40279, our previous study (H ANNUM REF)). The lists was ranked by adjusted p-value and selected the top 1000 markers for designing padlock probes for differentiating cancer (both LUNC and HCC) versus normal samples and a separate group of 1000 markers for differentiating LUNC versus HCC (Fig. 25).

[0299] All 2000 markers were used to design padlock probes for capture and sequencing of cfDNA. Padlock-capture of bis-DNA was based on the technique on methods of Deng, et al, 2009, Nature Biotechnology 27, 353-360; Diep, et al, 2012, Nature Methods 9, 270-272; and Porreca, et al., 2007, Nature Methods 4, 931-936; and with further modifications. Because of a relatively modest total size of captured regions/cg markers, this approach offers much lower cost of sequencing than any current methods including whole methylome-wide seqnencing, therefore enabling us to evaluate a large number of samples. Furthermore, the direct targeted sequencing approach offers digital readout, and requires much less starting cfDNA material (10-15 ng) than more traditional recent methods based on hybridization on a chip (eg. Infinium, Illumina) or target-enrichment by hybridization (eg. SureSelect, Agilent). This approach is also less sensitive to unequal amplification as it utilizes molecular identifiers (UMIs).

[0300] Padlock probe design, synthesis and validation

[0301] All probes were designed using the ppDesigner software. The average length of the captured region was 70 bp, with the CpG marker located in the central 80% of the captured region. A 6bp 6-bp unique molecular identifier (UMI) flanked capture arms to aid in eliminating amplification bias in determination of DNA methylation frequencies. Linker sequence between arms contained binding sequences for amplification primers separated by a variable stretch of Cs to produce probes of equal length. Probes were synthesized as separate oligonucleotides (IDT). For capture experiments, probes were mixed in equimolar quantities and purified on Qiagen columns.

[0302] Deep sequencing of the original pilot capture experiments showed significant differences between number of reads captured by most efficient probes and non-efficient probes (60-65% of captured regions with coverage >0.2x of average). To ameliorate this, relative efficiencies were calculated from sequencing data and probes were mixed at adjusted molar ratios. This increased capture uniformity to 85% of regions at > 0.5x of average coverage.

[0303] Targeted methylation sequencing using bis-DNA padlock probe capture

[0304] 10 ng of bisulfite-converted DNA was mixed with padlock probes in 20 μΐ reactions containing IX Ampligase buffer (Epicentre). To anneal probes to DNA, 30 second denaturation at 95°C was followed by a slow cooling to 55°C at a rate of 0.02°C per second and incubation for 15 hrs at 55°C. To fill gaps between annealed arms, 5μ1 of the following mixture was added to each reaction: 2U of PfuTurboCx polymerase (Agilent), 0.5U of Ampligase (Epicentre) and 250 pmol of each dNTP in IX Ampligase buffer. After 5 -hour incubation at 55°C, reactions were denatured for 2 minutes at 94°C. 5 μΐ of exonuclease mix (20U of Exo I and 100U ΕχοΠΙ of, Epicentre) was added and single-stranded DNA degradation was carried out at 37°C for 2 hours, followed by enzyme inactivation for 2 minutes at 94°C.

[0305] Circular capture products were amplified by PCR using primers specific to linker DNA within padlock probes. Both primers contained lObp barcodes for unique dual-index

multiplexing, and Illumina next-generation sequencing adaptor sequences. PCR was performed as follows: IX Phusion Flash Master Mix, 3 μΐ of captured DNA and 200nM primers, using the following cycle: 10s @ 98°C, 8X of (Is @ 98°C, 5s @ 58°C, 10s @ 72°C), 25X of (Is @ 98°C, 15s @ 72°C), 60s @ 72°C. PCR reactions were mixed and the resulting library was size selected on 2.5% agarose gels to include effective captures (~230bp) and exclude "empty" captures (~150bp). Purity of the libraries was verified by TapeStation (Agilent) and PCR using Illumina flowcell adaptor primers (p5 and p7) and the concentrations were determined using Qubit dsDNA HS assay (Thermo Fisher). Libraries were sequenced on MiSeq and HiSeq2500 systems

(Illumina) using PE100 reads. Median total reads for each sample was 500,000 and on-target mappability 25% (-125,000 on-target non-unique reads).

[0306] Optimization of capture coverage uniformity

[0307] Deep sequencing of the original pilot capture experiments showed significant differences between number of reads captured by most efficient probes and non-efficient probes (60-65% of captured regions with coverage >0.2x of average). To ameliorate this, relative efficiencies were calculated from sequencing data and probes were mixed at adjusted molar ratios. This increased capture uniformity to 85% of regions at > 0.5x of average coverage.

[0308] Sequencing data analysis [0309] Mapping of sequencing reads was done using the software tool bisReadMapper with some modifications. First, UMI were extracted from each sequencing read and appended to read headers within FASTQ files using a custom script. Reads were on-the-fly converted as if all C were non-methylated and mapped to in-silico converted DNA strands of the human genome, also as if all C were non-methylated, using Bowtie2. Original reads were merged and filtered for single UMI, i.e. reads carrying the same UMI were discarded leaving a single, unique read. Methylation frequencies were calculated for all CpG dinucleotides contained within the regions captured by padlock probes by dividing the numbers of unique reads carrying a C at the interrogated position by the total number of reads covering the interrogated position.

[0310] DNA isolation and digital Quantitative PCR

[0311] Tumor and corresponding plasma samples were obtained from patients undergoing surgical tumor resection; samples were frozen and preserved in at -80°C until use. Isolation of DNA and RNA from samples was performed using DNA/RNA MiniPrep kit and a cfDNA extraction kit, respectively (EliteHealth, Guangzhou Youze, China). To estimate tumor cfDNA fractions, mixing experiments were performed with various fractions of normal cfDNA and HCC tumor genomic DNA (gDNA) and assayed methylation values and copy numbers by dPCR (see next section for details). Digital droplet PCR (ddPCR) was performed according to the manufacturer's specifications (Bio-Rad, Hercules, CA). The following ddPCR assay was used in this study: cgl 0590292 - forward primer 5'-TGTTAGTTTTTATGGAAGTTT, reverse primer 5'- AAACIAACAAAATACTCAAA; fluorescent probe for methylated allele detection 576- F AM/TGGGAGAGCGGGAGAT/BHQ 1 /-3 '; probe for unmethylated allele detection,

5 '/HEX/TTTGGGAGAGTGGGAGATTT/BHQ 1 /-3 ' . ddPCR was performed according to the manufacturer's specifications (Bio-Rad, Hercules, CA). using the following cycling conditions: IX of 10 mins @ 98°C, 40X of (30s @ 98°C, 60s @ 53°C), IX of 10 mins @ 98°C.

[0312] Calculation of tumor cfDNA fraction

[0313] It was assumed that a particular methylation value observed for an HCC cfDNA sample results from the combined contribution of normal and tumor cfDNA. The fraction of cfDNA originating from the tumor was estimated using the following formula: fraction contributed from tumor DNA in sample i = [methylation value in HCC cfDNA in sample i - mean methylation value of normal cfDNA] / [mean methylation value of tumor DNA - mean methylation value of normal cfDNA]. Using this approach, it was estimated that on average the tumor fraction is around 23% in HCC cfDNA samples. Samples were then grouped according to factors that evaluate tumor load, such as an advanced stage and pre-treatment status, since these factors are expected to affect the tumor fraction in ctDNA. Indeed, it was observed that conditions associated with a higher tumor staging and severity also tended to have a larger tumor fraction. To further vet this approach, a mixing experiment with different fractions of normal cfDNA (0-100%) and tumor genomic DNA (0-100%) was performed and assayed methylation values using digital PCR. It was shown that incremental addition of tumor genomic DNA can increase methylation fraction percentage up to the values observed in the HCC patient samples. Specifically, addition of 10%, 20%, 40%, 60% or 100% fraction of tumor genomic DNA can be predicted by the above formula, when using methylation values obtained from the experiment.

[0314] Statistical Analysis

[0315] DNA methylation marker selection for diagnostic and prognostic analysis

[0316] Out of 2000 initially designed padlock probes, only 1673 were informative, i.e able to give positive and specific PCR amplification signals, and thus were used as capture probes in the subsequent experiments in cfDNA samples. Sequencing depth was used as a sample inclusion criterion. Samples where less than 100 MCB (see below) showed lOx read coverage were excluded from further analysis. Since each MCB incorporated on average ~3 CG markers, the lOx coverage ensured at least 30 methylation measurements per MCB. Using these criteria, 73% of all samples with a median of 34K mapped reads per sample were included.

[0317] After having obtained DNA methylation data for 1673 CG markers, the concept of MCBs to merge proximal CpG markers into a MCB was used, resulting in a total of 888 MCBs. For each MCB, the MCB-specific methylation value was quantified with two numbers: loglO (total methylated read count +1) and loglO (total unmethylated read count +1), using the log transform to reduce outlier effects.

[0318] About 1673 informative padlock probes were obtained that were able to give positive and specific PCR amplification signals and they were used as capture probes in the subsequent experiments in cfDNA samples. cfDNA samples with less than 100 MCB of >30x coverage were also eliminated. Methylated reads for each marker were defined as total unique methylated reads and methylation values for each marker were defined as the proportion of read counts with methylation divided by total read counts.

[0319] cfDNA-based diagnostic classifier construction using MCBs (cd-score)

[0320] cfDNA sample data obtained from patients diagnosed with liver cancer (HCC), lung cancer (LUNC) and normal controls were divided into training and validation cohorts. The full dataset was randomly split with a 1: 1 ratio to form the training and validation cohorts.

[0321] Marker selections: Within the training cohort, the "randomized lasso" scheme was adopted to reduce the sampling dependency and stabilize variable selection in order to select biomarkers with high confidence. The training set was first randomly divided with 1 : 1 ratio. The variable selection procedure on two thirds of the samples was conducted and withheld a third of the samples for evaluating performance of the feature selection process. The feature selection process consisted of two steps repeated 50 times. MCBs were included for training the final model if they were selected in 40 out of 50 feature selection iteration. A multi-class prediction system based on Friedman et al, 2010, J Stat Softw 33, 1-22 was constructed to predict the group membership of samples in the test data using the panel of MCBs selected. A confusion matrix and ROC curves were also provided to evaluate sensitivity and specificity, in addition to prediction accuracy based on the held out partition of the training set.

[0322] Classification process: a two-step classification process was employed: cancer vs normal, LUNC vs HCC by building two binary multinomial logistic regression models. The multinomial logistic regression has the advantage where it can yield an intuitive probability score and allow for easier interpretation. For example, if the cancer-vs-normal model yield a probability score of 70% for a given methylation profile, it suggests that the patient has a 70% chance of having cancer. In order to minimize the number of false cancer predictions, the cancer prediction confidence threshold was set to 80%. For patients with at least 80% chance of cancer, the cancer - vs-cancer regression model was applied for classifying between LUNC and HCC, the classification model would decide only if the classified sample has a confidence of over 55%.

[0323] Building a predictive model for prognosis and survival

[0324] The potential to use a combined prognosis score (cp-score) system based on both methylation reads and non-methylated reads was investigated for each MCB in cfDNA for prediction of prognosis in LUNC and HCC in combination with clinical and demographic characteristics including age, gender, and AJCC stage. For each type of cancer, a cp-score model was build and validate it by randomly selecting half of the observations from the full dataset as the training cohort, and treated the rest as the validation cohort. Variable selection on the training cohort was conducted and built the composite score on the validation cohort. Within the training cohort, the "randomized lasso" scheme was adopted to reduce the sampling dependency to stabilize the variable selection in order to select biomarkers with a high confidence. The entire cohort was randomly divided with a 1 : 1 ratio. The variable selection procedure was conducted on two-thirds of the training cohort. LASSO was implemented with an optimal tuning parameter determined by either the expected generalization error from the 10-fold cross validation or the information based criteria AIC / BIC, whichever yielded the highest (the proportion of explained randomness) with the selected biomarkers. The 10 most recurring features from HCC and in LUNC (Table 8) was then aggregated. To evaluate the predictability of each panel externally, a composite score was obtained for each patient in the validation cohort by multiplying the unbiased coefficient estimates from the Cox regression and the methylation reads. A Kaplan- Meier curve and log-rank test were generated using the dichotomized composite score, which formed a high-risk and low-risk group membership assignment according to its median. This segmentation was compatible with that formed by AJCC stage. Time-dependent ROC was used to summarize the discrimination potential of the composite score, AJCC stage and the combination of two, with ROC curves varying as a function of time and accommodating censored data. Finally, a multivariate Cox regression model was also fitted to assess the significance of potential risk factors.

[0325] All the analysis was conducted in R (version 3.2.3) and python (version 2.7.13) with the following packages used: 'glmnet', 'limma',' survival', 'sklearn', 'lifeline' ,' survival ROC, 'survcomp',

[0326] All hypothesis testing was done by two-sided with p-value < 0.05 considered to be statistically significant unless specifically stated otherwise.

[0327] Patient and sample characteristics

[0328] Clinical characteristics and molecular DNA methylation profiles were collected for 827 LUNC and 377 HCC tumor samples from The Cancer Genome Atlas (TCGA) and 754 normal samples from a dataset used in our previous methylation study on aging (GSE40279) (Hannum et al, 2013). Two cohorts of patients were studied. The first cohort was from solid tumor samples from TCGA and the second cohort was from plasma samples from China. To study cfDNA in LUNC and HCC, plasma samples were obtained from 2,396 Chinese patients with HCC or LUNC, and from randomly selected, population-matched healthy controls undergoing routine health care maintenance, resulting in a cohort of 892 LUNC and 1504 HCC patients and 2247 normal healthy controls. Informed written consent was obtained from each study participant. Clinical characteristics of all patients and controls are listed in Table 9.

[0329] Identification of methylation markers differentiating LUNC and HCC and blood

[0330] Previous reports indicate that plasma contains DNA released from tissues within the body. It was hypothesized that because cfDNA originating from tumor cells can be detected in a background of cfDNA predominantly released from leukocytes, CpG markers with a maximal difference in methylation values between LUNC or HCC versus normal leukocytes would be most likely to demonstrate detectable methylation differences in the cfDNA of HCC or LUNC patients when compared to that of normal controls. To identify putative markers, methylation data derived from cancer tissue DNA from the TCGA and normal blood including 827 LUNC, 377 HCC, and 754 blood samples from healthy controls were compared. In order to identify DNA sites with significantly different rates of methylation between LUNC or HCC and normal blood, a t-statistic with Empirical Bayes was used for shrinking the variance and selected the top 1000 significant markers, using the Benjamini-Hochberg procedure to control the FDR at a significance level of 0.05. Unsupervised hierarchical clustering of these top 1000 markers was able to distinguish between LUNC, HCC, and normal blood, and between LUNC and HCC (Fig. 25). About 2,000 molecular inversion (padlock) probes corresponding to these 2000 markers for capture-sequencing cfDNA from plasma (1000 for cancer versus normal and 1000 for LUNC versus HCC) were then designed.

[0331] cfDNA diagnostic prediction model for LUNC and HCC [0332] The methylation data of the 888 selected Methylation Correlated Blocks (MCB) that showed good methylation ranges in cfDNA samples were further analyzed to identify MCBs that showed significantly different methylation between cancer samples (LUNC and HCC) versus normal control samples. Unsupervised hierarchical clustering of these selected MCBs using methylated reads across samples is shown in Fig. 25C, and distributions of MCB methylated read values for normal, LUNC and HCC samples is shown in Fig. 26. The entire methylation dataset of 888 MCBs was therefore analyzed by Least Absolute Shrinkage and Selection Operator (LASSO) method and further reduced the number of MCBs. LASSO-based feature selection identified 28 MCBs for discriminating LUNC versus HCC and normal, 27 MCBs for

discriminating of HCC versus LUNC and normal, 22 MCBs for discriminating of normal vs HCC and LUNC, resulting in 77 unique markers (5 MCBs overlap between models). This approach combined the information captured by the MCBs into a composite cfDNA -based score

(composite diagnostic score: cd-score). The utility of this score was evaluated for predicting the presence of LUNC or HCC using a hold-out strategy where samples were randomly assigned to a training set and a validation set with a 1 : 1 ratio. The scoring system was trained using 229 LUNC, 444 HCC and 1123 normal control cfDNA samples and then validated on 300 LUNC, 445 HCC and 1124 normal samples. Applying the fitted model to the validation set samples yielded a sensitivity of 92.4% for HCC and 85.8% for LUNC, and a specificity of 99.0% for normal controls in a multi-classification scheme (Table 6A). It was found that this model could successfully differentiate LUNC and HCC samples from normal controls in the validation cohort (AUC cancer vs normal=0.979; AUC LUNC vs HCC=0.924; Fig. 19A, Table 6B, Table 6C). Unsupervised hierarchical clustering of the 77 MCBs was able to distinguish HCC and LUNC from normal controls with high specificity and sensitivity (Fig. 19C and Fig. 19D).

[0333] Liver diseases, such acirrhosis, and fatty liver, are major risk factors for HCC. Thus, the cd-score of the model was assessed for differentiating between liver diseases and. It was found that the cd-score was able to differentiate HCC patients from those with liver diseases or healthy controls (Fig. 20A). These results were consistent and comparable with those predicted by AFP levels in HCC (Fig. 20B). The cd-score could also differentiate between LUNC patients and non- LUNC patients with a smoking history (> 1 pack/day for ten years) who were at an increased risk of LUNC (Fig. 20C). These results were consistent and comparable with those predicted by AFP levels in HCC (Fig. 20D).

[0334] Methylation profiles predicted tumor burden, treatment response and staging

[0335] Next, the utility of the cd-score was studied in assessing treatment response, the presence of residual tumor following treatment, and staging of LUNC and HCC. In LUNC, the cd-scores of patients with detectable residual tumor following treatment (n=559) were significantly higher than those with no detectable tumor (n=160) (pO.001, Fig. 21 A). Similarly, there was good correlation between the cd-scores and tumor stage. Patients with early stage disease (I, Π) had substantially lower cd-scores compared to those with advanced stage disease (III, IV) (p=<0.005, Fig. 21B). In addition, the cd-scores were significantly lower in patients with complete tumor resection after surgery (n=158) compared with those before surgery (n=67), yet became higher in patients with recurrence (n=56) (p< 0.01, Fig. 21C). Furthermore, the cd-scores were significantly higher in patients before treatment (n=67) or with progression (n=136) compared to those with a positive treatment response (n=328) (p< 0.001, Fig. 21D). In HCC, The cd-scores of patients with detectable residual tumor following treatment (n=889) were significantly higher than those with no detectable tumor (n=314) (pO.0001, Fig. 21E). Similarly, there was a highly positive correlation between cd-scores and tumor stage. Patients with early stage disease (I, II) had substantially lower cd-scores compared to those with advanced stage disease (ΙΠ, IV) (pO.001, Fig. 2 IF). In addition, the cd-scores were significantly lower in patients with complete tumor resection after surgery (n=293) compared with those before intervention (n=109), yet became higher in patients with recurrence (n=155) (p<0.0\, Fig. 21 G). Furthermore, the cd-scores were significantly higher in patients before treatment (n=109) or with progression (n=381) compared to those with treatment response (n=249) (p< 0.001, Fig. 21H). Serial longitudinal dynamic changes were obtained of methylation values of CpG site

cgl0673833 in several individuals with LUNC or HCC patient in order to monitor treatment response and found there was a high correlation between methylation values and treatment outcomes (Fig. 28, Fig. 29 and Fig. 30). Collectively, the results showed the significant correlation between he cd-score (i.e., the amount of cfDNA in plasma) and tumor burden, demonstrating its utility for the prediction of tumor response and for surveillance to detect recurrence.

[0336] Diagnostic utility of cfDNA as compared with AFP and CEA

[0337] Despite enormous efforts, an effective noninvasive blood-based biomarker for surveillance and diagnosis of LUNC and HCC is still lacking. CEA (cancer embryonic antigen) and AFP have filled this role for lung cancer and HCC for decades, but its sensitivity and specificity are inadequate. Moreover, some patients with squamous cell carcinoma or small cell lung cancer will not have increased blood CEA levels. AFP has low sensitivity of 60%, making it inadequate for detection of all patients that will develop HCC and thus severely limiting its clinical utility. In fact, it is common for cirrhotic patients with HCC to show no increase in AFP levels. Strikingly, 30% patients of the HCC study cohort have a normal AFP value (<25 ng/ml). In biopsy-proven LUNC patients of the entire cohort, the cd-score demonstrated superior sensitivity and specificity to CEA for LUNC diagnosis (AUC 0.977 (cd-score) vs 0.856 (CEA), Fig. 21Q). Both cd-score and CEA values were highly correlated with tumor stage (Fig. 21 J, Fig. 21B). On other hand, the cd-score demonstrated superior sensitivity and specificity to AFP for HCC diagnosis (AUC 0.993 vs 0.835, Figure 4R) in biopsy-proven HCC patients. Both cd-score and AFP values were highly correlated with tumor stage (Fig. 21F and Fig. 21N). In patients with treatment response, tumor recurrence, or progression, the cd-score showed more changes from initial diagnosis than that of AFP (Fig. 21G and Fig. 21H, Fig. 210 and Fig. 21P). In LUNC patients with treatment response, tumor recurrence, or progression, the cd-score showed more significant changes from initial diagnosis than that of CEA (Fig. 21C and Fig. 21D, Fig. 21K and Fig. 21L). In LUNC and HCC patients with serial samples, there was a concomitant and significant decrease in cd-score in patients with a positive treatment response than in patients prior to treatment. There was an even further reduction in cd-score in patients after surgery. In contrast, there was an increase in methylation rate in patients with progressive or recurrent disease (Fig. 28). By comparison, CEA and AFP were less sensitive for assessing treatment efficacy in individual patients (Fig. 29 and Fig. 30).

[0338] cfDNA prognostic model for HCC and LUNC

[0339] The potential of using a combined prognosis score (cp-score) based on cfDNA methylation analysis for prediction of prognosis in LUNC and HCC in combination with clinical and demographic characteristics including age, gender, AJCC stage, and AFP value was investigated. Totally 599 LUNC patients and 867 HCC patients enrolled in prognosis analysis (patients without tumor burden are excluded from the analysis). The median follow up time was 9.5 months (rang 0.6-26 months) in LUNC cohort and 6.7 months (rang 1.2-21.0months) in HCC cohort. In the HCC cohort, the training dataset contained 433 observations with 41 events and the validation dataset contained 434 observations with 58 events. By using statistical learning methods, a predictive model was constructed using 10 CpG MCBs (Table 8) that can separate the HCC cohort into high and low risk groups, with median survival significantly greater in the low- risk group than in the high-risk group (log-rank test = 24.323, df=l, /?<0.001) (Fig. 22A). In the LUNC cohort, the training dataset contained 299 observations with 61 events and the validation dataset contained 434 observations with 58 events. A panel of 10 CpG markers (Table 8) was able to divide the LUNC cohort into high and low risk groups, with median survival significantly greater in the low-risk group than in the high-risk group (log-rank test= 6.697, άΐ=\, ρ<0.00\) (Fig. 22B).

[0340] Multivariate Cox regression model showed that the cp-score was significantly correlated with incidence of mortality in both HCC and LUNC. The cp-score was an independent risk factor of survival both in HCC and borderline in LUNC validation cohorts (harzard ratio 2.488 ! . p 0.00072 ! in HCC; hazard ratio= 1.74, p 0.068 in l .l . ^' NC: p 0.00 1 7 In LUNC; Table 10). Interestingly, when cp-score and other clinical characteristics were taken into account in HCC, AFP was no longer significant as a risk factor (Table 1 1). As expected, TNM stage (as defined by AJCC guidelines) predicted the prognosis of patients both in HCC (Fig. 22C) and LUNC (Fig. 22D). The combination of cp-score and TNM staging improved our ability to predict prognosis in both HCC (AUC 0.867, Fig. 22E) and LUNC cohort (AUC 0.825, Fig. 22F).

[0341] Methylation markers in early diagnosis of LUNC and HCC

[0342] Since LUNC and HCC are very aggressive cancers with poor prognosis and survival, and surgical removal of cancer at stage 1 carries a much more favorable prognosis, early detection becomes a key strategy in reducing morbidity and mortality. The method of using methylation markers for predicting cancer occurrence in high-risk populations was investigated in two prospective studies. In the first study, consecutive patients were recruited from a group of patients with solid lung nodules >10mm identified on chest CT scans. These patients were enrolled in a study for early lung detection in smokers and underwent CT scan-based lung cancer screening. Patients presenting with a solid lung nodule (between 10mm and 30mm in size, n=208, Table 11) were selected to undergo methylation profiling at the time of screening. These patients were subsequently followed through secondary testing to determine whether nodules were due to LUNC or a benign condition due to inflammation or infection by tissue biopsy and pathology verification. The methylation profile was sufficient to differentiate patients with biopsy-proven stage 1 LUNC lesions compared to patients with benign nodules due to inflammatory or infectious conditions (Fig. 23, Table 12). Among the patients with at least 59% confidence for diagnosis, Positive predictive value (PPV) of stage I cancer was 95.9% and negative predictive value (NPV) was 97.4 %. Similarly, high risk HCC patients with liver cirrhosis (n=236, Table 1 1) were prospectively enrolled. The methylation profile was able to predict progression to stage 1 HCC with 89.5% sensitivity and 98.2% specificity (Fig. 24, Table 12) among the patients with at least 58% confidence for diagnosis. PPV was 80.9% and NPV was 99.1%.

[0343] In this study, differentially methylated CpG sites were first determined in LUNC and HCC tumor samples versus normal blood. Then, these markers were interrogated in the cfDNA of a large cohort of LUNC and HCC patients as well normal controls. A diagnostic model (cd-score) was developed using methylation of cfDNA to predict the presence of cancer, while at the same time differentiating between LUNC and HCC.

[0344] The cd-score discriminated patients with HCC from individuals with HBV/HCV infection, cirrhosis, and fatty liver disease as well as healthy controls. In some instances, it is important that a serum test reliably distinguish these disease states from HCC. According to the results, the sensitivity of the cd-score for HCC is comparable to liver ultrasound, the current standard for HCC screening. In addition, in some instances it is superior to AFP, the only clinically used biomarker for HCC, making cd-score a more cost-effective and less resource- intensive approach. Furthermore, by showing its high correlation with HCC tumor burden, treatment response, and stage, the cd-score of the model demonstrated superior performance than AFP in the instant cohort (AFP values were within a normal range for 40% of our HCC patients during the entire course of their disease). In some cases, the cd-score may be particularly useful for assessment of treatment response and surveillance for recurrence in HCC. Since nearly all of the HCC patients had hepatitis (most likely hepatitis B) in the study, HCC arising from other etiologies may have different cfDNA methylation patterns. Similar to HCC, screening for lung cancer has a high cost, involving CT imaging of the chest, which has an associated radiation exposure and a high false-positive rate. In some cases, the cd-score reliably distinguished smokers and patients with lung cancer and may also have utility in improving screening and surveillance.

[0345] Prognostic prediction models were also constructed for HCC and LUNC from the cp- score. The cp-score effectively distinguished HCC and LUNC patients with different prognosis and was validated as an independent prognostic risk factor in a multi -variable analysis in our cohorts. Of note, for predicting prognosis in HCC, cfDNA analysis was again superior to AFP. In some cases, this type of analysis is helpful for identification of patients for whom more or less aggressive treatment and surveillance is needed.

[0346] Table 6A. Contingency table of multi-classification diagnosis in validation cohort

Table 6B. Contingency table of binary classification diagnosis between HCC and

Table 6C. Contingency table of binary classification diagnosis between LUNC and

Correct 188 921

Sensitivity (%) 97.4

Specificity (%) 98.3

[0349] Table 7. List of MCBs selected by multi-class LASSO and used for cd-score generation. A, normal; B, LUNC; C, HCC.

A, Normal

6-912971 mc cg01087382 MAP3K7 0.132083258 -0.263202543 non mc cg01087382 MAP3K7 0.023651284 0.314783378

7-1017626 mc cg06721601 CUX1 0.305704307 0.347231675 non mc cg06721601 CUX1 -0.061678409 0.340362292

7-1577443 mc cg27104173 PTPRN2 0.029132702 -0.207025939 non mc cg27104173 PTPRN2 0.004420766 -0.098341178

9-885141 mc cgl3740515 - 0.028390415 -0.269846773 non mc cgl3740515 - -0.208939054 -0.193859618

X-27307 mc cgl 3176022 XG 0.511857283 0.042177783 non mc cgl 3176022 XG 0.048888339 -0.232292001

B: LUNC

non mc cg20626840 FAM82A1 0.272198397 0.04877136 mc cgl5545942 ASAP2 -0.557516889 -0.185093352

2-95267

non mc cgl5545942 ASAP2 -0.11738118 -0.171014921 mc cg06722069 - -0.427422216 -0.26910555

3-1138223

non mc cg06722069 - 0.089047399 -0.071525276 mc cg04466840 RGS14 -0.206022964 -0.032074773

5-1767847

non mc cg04466840 RGS14 -0.029935092 0.110871368 mc cgl 7757602 - 0.041309712 0.029262464

5-429520

non mc cgl 7757602 - -0.133713183 -0.355503949 mc cgl7475813 ARID1B 0.129475454 0.045380298

6-1574304

non mc cgl7475813 ARID1B -0.398696708 -0.14398793 mc cg08343881 ZNF323 0.002401379 0.00651448

6-283040

non mc cg08343881 ZNF323 0.255186684 0.345026825 mc cg02919168 DEF6 -0.372390965 -0.054727228

6-352655

non mc cg02919168 DEF6 0.070785826 -0.098822441 mc cg01087382 MAP3K7 0.132083258 -0.263202543

6-912971

non mc cg01087382 MAP3K7 0.023651284 0.314783378 mc cg06721601 CUX1 0.305704307 0.347231675

7-1017626

non mc cg06721601 CUX1 -0.061678409 0.340362292 mc cg22024657 SLC13A1 0.013826947 0.222664259

7-1228399

non mc cg22024657 SLC13A1 -0.056854833 0.037841165 mc cgl 8004756 GRHL2 -0.293288901 0.034342458

8-1025044

non mc cgl 8004756 GRHL2 -0.043777572 -0.203017346 mc cgl2188860 TOP1MT 0.094522888 -0.083700307

8-1444164

non mc cgl2188860 TOP1MT -0.083425117 -0.026557506

C: HCC

mc cgl2054453 TMEM49 0.062499156 -0.478242327

17-579157

non mc cgl2054453 TMEM49 0.549358501 0.925660526 mc cg20651080 DUS1L 0.16564247 0.179098878

17-800195

non mc cg20651080 DUS1L -0.072821844 0.405200855 mc cgl 1252953 C17orfl01 0.009872935 0.197906181

17-803588

non mc cgl 1252953 C17orfl01 -0.088619833 -0.047902639 mc cg06663668 CD3EAP 0.026258194 0.077247979

19-459097

non mc cg06663668 CD3EAP -0.209537326 0.55413999 mc cgl l441617 CNOT3 -0.272150647 0.31583956

19-546460

non mc cgl l441617 CNOT3 -0.485831577 0.011388271 mc cgl l441617 CNOT3 0.345456601 0.601027916

19-546461

non mc cgl l441617 CNOT3 0.252775143 0.151478291 mc cg09366118 PSD4 0.098868936 0.269196214

2-1139315

non mc cg09366118 PSD4 0.039975437 -0.005683265 mc cg01519261 RUNX1 0.350276252 0.086780025

21-364214

non mc cg01519261 RUNX1 0.205448988 -0.230292808 mc cg01519261 RUNX1 -0.068910744 0.175787941

21-364215

non mc cg01519261 RUNX1 -0.470630509 -0.686309747 mc cg02415779 - 0.056697461 0.313717112

22-185277

non mc cg02415779 - 0.122239689 -0.243806777 mc cg00107982 ELFN2 -0.03021978 0.143360514

22-378130

non mc cg00107982 ELFN2 -0.063348947 0.490504707 mc cg07748255 MAEA 0.217866978 -0.457591409

4-13248

non mc cg07748255 MAEA -0.011474644 -0.340582424 mc cgl9255783 PLAC8 0.024851345 0.211399591

4-840359

non mc cgl9255783 PLAC8 -0.154998544 -0.217029094 mc cg25650256 STK10 -0.296078256 0.069437129

5-1715385

non mc cg25650256 STK10 -0.134013643 0.178025221 mc cg05414338 HIST1H3F -0.291906307 0.385669376

6-262504

non mc cg05414338 HIST1H3F -0.188285503 0.279553121 mc cg06393830 NFKBIL1 0.120351939 0.122094253

6-315278

non mc cg06393830 NFKBIL1 0.206309569 -0.082505936 mc cg00862588 HLA-DMB -0.322857861 0.005678509

6-329093

non mc cg00862588 HLA-DMB 0.382920486 -0.054366936 mc cg01087382 MAP3K7 0.132083258 -0.263202543

6-912971

non mc cg01087382 MAP3K7 0.023651284 0.314783378 mc cg03113878 C7orf51 -0.173651065 -0.291203774

7-1000913

non mc cg03113878 C7orf51 -0.009576582 0.090427416 mc cg21217886 HSPB1 -0.135144273 -0.558395663

7-759325

non mc cg21217886 HSPB1 -0.163997602 -0.133445148

[0350] Table 8. Characteristics of 10 MCBs in LUNC prognosis prediction and 10 MCBs in HCC prognosis prediction Features Target ID RefGene

mc_l 7-742484 cg24166450 - non mc 2-741532 cg02478828 DGUOK

mc_2-2355288 cg08436738 - mc_l-295863 cg04933208 PTPRU

non mc 22-358223 cg20146967 MCM5

LUNC

non_mc_l 6-900927 cg07860918 GAS 8

mc_20-374337 cgl6119522 PPP1R16B non_mc_3-1960650 cg05556202 TM4SF19

mc_12-687588 cg20323175 - non_mc_l 0-299484 cgl3324103 SVIL

mc_6-262503 cg05414338 HIST1H3F mc_6-733300 cgl7126142 KCNQ5

non_mc_7-450187 cg06787669 MYOIG

mc_19-185898 cg06747543 ELL

mc_l 2- 1222773 cg26386472 HPD

non mc 1-20665 cg00866690 PRKCZ

mc_l 2-939663 cgl 1225410 SOCS2

mc_7-450187 cg06787669 MYOIG

mc_6-283040 cg08343881 ZNF323

HCC mc_6-733299 cgl7126142 KCNQ5

51] Table 9. Clinical characteristics of study cohort

TCGA TCGA

Characteristic GSE HCC LUNC Normal

HCC tissue LUNC

tissue Normal blood blood blood

Total (n) 377 827 754 1504 892 2247

Gender

Female-no. (%) 122(32.4) 340(41.1) 401(53.2) 146(9.7) 263(29.5) 507(22.6) Male-no. (%) 255(67.6) 487(58.9) 353(46.8) 991(65.9) 487(54.6) 480(21.4)

NA 0 0 0 367(24.4) 142(15.9) 1260(56.1)

Age (years)

Mean 61 68 63 54 58 48 Range 16-90 33-90 19-101 11- 85 19-85 19-90 Pathology

Hepatocellular 367(97.3) 0 NA 1504(100) 0 NA

Adenocarcinoma(%) 0 458(55.4) NA 0 402 (45.1) NA

Squamous cell 0 369(44.6) NA 0 138(15.5) NA

Small Cell Lung 0 0 NA 0 79(8.9) NA

Others(%) 10(2.7) 0 NA 0 273(30.6) NA

Stage

I (%) 175(46.4) 424(51.3) NA 206(13.7) 58(6.5) NA

II (%) 87(23.1) 115(13.9) NA 202(13.4) 52(5.8) NA

III (%) 86(22.8) 261(31.6) NA 612(40.7) 148(16.6) NA

IV (%) 6(1.6) 25(3.0) NA 134(8.9) 463(51.9) NA

NA (%) 23(6.1) 2(0.2) NA 350(23.3) 171(19.2) NA

Tumor burden

Tumor free (%) 236(62.6) 503(60.8) NA 314(20.9) 160(17.9) NA

With tumor (%) 114(30.2) 159(19.2) NA 889(59.1) 599(67.2) NA

NA (%) 27(7.2) 165(20.0) NA 301(20.0) 133(14.9) NA

EGFR status

Wide type (%) NA 400(48.4) NA NA 102(11.4) NA

Mutation (%) NA 100(12.1) NA NA 69(7.7) NA

NA (%) NA 327(39.5) NA NA 721(80.8) NA

Hepatitis

Positive (%) 120(31.8) NA NA 623(95.3) NA 379(16.9)

Negative (%) 119(31.6) NA NA 10(1.5) NA 571(25.4)

NA (%) 138(36.6) NA NA 21(3.2) NA 1297(57.7)

Smoking (%)

Current smoker (%) NA 725(87.7) NA NA NA 192(8.5)

Non-smoker (%) NA 80(9.7) NA NA NA 670(29.8)

NA (%) NA 22(2.6) NA NA NA 1385(61.6)

[0352] Table 10. Multivariate survival analysis for HCC patients and LUNC patients with composite-score of methylation markers (cp-score) and relevant variables in validation cohorts

[0353] Table 11. Clinical characteristics and sensitivity/specificity for detection of stage I

LUNC and benign lung nodules

[0354] Table 12. Clinical characteristics and sensitivity/specificity for detection of progression to stage I HCC from liver cirrhosis

Sensitivity— % (95% CI) 94.9

Specificity— % (95% CI) 92.6

Positive predictive value— % (95% CI) 94.9

Negative predictive value— % (95% CI) 92.8

[0355] EXAMPLE 5 - Circulating Tumor DNA Methylation Profiles for Diagnosis and Prognosis of Colorectal Cancer

[0356] Colorectal cancer (CRC) is one of the most common cancers in the world. In some instances, detection of CRC at early and/or intermediate stage provides a better prognosis than detection at an advanced stage. Serum Carcinoembryonic antigen (CEA) quantification is a non- invasive tool for the detection of cancer. However, in some instances, the CEA test has a low sensitivity for the detection of CRC.

[0357] Circulating tumor DNA (ctDNA) is tumor-derived fragmented DNA in the circulatory system, comes, e.g., from dead tumor cells through necrosis and apoptosis. In this study, DNA methylation status of genes obtained from ctDNA samples are determined and are further utilized for detection of CRC.

[0358] Patient data

[0359] Tissue DNA methylation data was obtained from The Cancer Genome Atlas (TCGA). Complete clinical, molecular, and histopathological datasets are available at the TCGA website. Whole blood DNA methylation profiles from healthy donors were generated in an aging study (GSE40279) in which DNA methylation profiles for CRC and blood were analyzed. Individual institutions that contributed samples coordinated the consent process and obtained informed written consent from each patient in accordance to their respective institutional review boards.

[0360] The cfDNA cohort consisted of 801 CRC patients and 1021 normal control from the Sun Yat-sen University Cancer Center in Guangzhou, Xijing Hospital in Xi'an, and the West China Hospital in Chengdu, China. Patients who presented with CRC from stage I-IV were selected and enrolled in this study. Patient characteristics and tumor features are summarized in Table 18. The TNM staging classification for CRC is according to the 7 ^th edition of the AJCC cancer staging manual. This project was approved by the institutional review board of Sun Yat- sen University Cancer Center, Xijing Hospital, and West China Hospital. Informed consent was obtained from all patients. Human blood samples were collected by venipuncture, and plasma samples were obtained by taking the supernatant after centrifugation and stored at -80°C before cfDNA extraction.

[0361] Prospective CRC screening cohort study

[0362] A CRC study was conducted using plasma samples on screening and early detection of a high-risk screening population in order to assess feasibility of using methylation markers for predicting CRC occurrence in high-risk populations. The cohort included individuals whom based on questionnaires were definition as high risk with CRC, and individuals whom are asymptomatic and aged 45 or above scheduled for screening colonoscopy from Sep 2015- Dec 2017. A total of 1450 subjects at high risk of CRC were scheduled for colonoscopy and cfDNA methylation test with the following situation: (i) age >45 years, (ii) ever smoking, alcohol consumption, diabetes mellitus; (iii) family history present (two or more first degree relatives with CRC or one or more with CRC at age 50 years or less; or known Lynch syndrome or familial adenomatous polyposis); (iv) had positive results on fecal blood testing or change in bowel habit, excluded subjects were those who had a personal history of colorectal neoplasia, digestive cancer, or inflammatory bowel disease; had undergone colonoscopy within the previous 10 years or a barium enema, computed tomographic colonography, or sigmoidoscopy within the previous 5 years; had undergone colorectal resection for any reason other than sigmoid diverticula; had overt rectal bleeding within the previous 30 days. The present study

prospectively recruited screening subjects who gave informed consent and received colonoscopy in this program. This project was approved by the IRBs of Sun Yat-sen University Cancer Center, Xijing Hospital, and West China Hospital.

[0363] Statistical Analysis

[0364] Solid tumor and whole blood methylation profiles

[0365] DNA methylation data of 485,000 sites generated using the Infinium 450K Methylation Array were obtained from the TCGA and a dataset generated from an aging study (GSE40279) in which DNA methylation profiles for CRC and blood were analyzed. Both primary solid tissues from cancer patients and whole blood from healthy donor were measured by Illumina 450k infimum bead chip. ID AT format files of the methylation data were generated containing the ratio values of each scanned bead. Using the minfi package from Bioconductor, these data files were converted into a score, referred to as a Beta value. Methylation values of the Chinese cohort were obtained by targeted bisulfite sequencing using a molecular inversion probe and analyzed as described below.

[0366] DNA methylation marker pre-selection for diagnostic and prognostic analysis

[0367] A differential methylation analysis on TCGA data using a "moderated t-statistics shrinking" approach was performed and the p-value for each marker was then corrected by multiple testing by the Benjamini-Hochberg procedure to control FDR at a significance level of 0.05. The list was ranked by adjusted p-value and the top 1000 markers were selected for designing padlock probes for differentiating CRC versus normal samples. 1,000 molecular inversion (padlock) probes were then designed corresponding to these 1000 markers for capture- sequencing of cfDNA in CRC plasma. All padlock probe design and capture of bis-DNA were based on published techniques with some modification. Only 544 padlock probes were able to give positive and specific PCR amplification signals and they were therefore used as capture probes in the subsequent experiments in cfDNA samples. cfDNA samples with low quality or fewer than 30,000 reads per sample were also eliminated. About 1822 cfDNA samples were included in the subsequent study (801 CRC blood samples and 1021 normal blood samples). Methylated reads for each marker were defined as total unique methylated reads and methylation values for each marker were defined as the proportion of read counts with methylation divided by total read counts. For particular methylation markers with less than 20 unique reads, an imputed mean methylation value of CRC or normal healthy controls were used.

[0368] Building a diagnostic model

[0369] cfDNA sample data obtained from patients diagnosed with CRC ( n=801 ) and healthy contol (n=1021) was randomly split into training and validation cohorts with a 2: 1 ratio. Next, two variable selection methods were applied which were suitable for high-dimensionality on the prescreened training dataset: Least Absolute Shrinkage and Selection Operator (LASSO) and Random Forest based variable selection method using OOB error. As results can depend strongly on the arbitrary choice of a random sample split for sparse high-dimensional data, an analysis of the "multi-split" method was adopted, which improved variable selection consistency while controlling finite sample error. For LASSO selection operator, 75 percent of the dataset were subsampled replacement 500 times and the markers were selected with repeat occurrence frequency of more than 450. The tuning parameters was determined according to the expected generalization error estimated from 10-fold cross-validation and information -based criteria AIC/BIC, and the largest value of lambda was adopted such that the error was within one standard error of the minimum, known as "1-se" lambda. For the random forest analysis, using the OOB error as a minimization criterion, variable elimination was carried out from the random forest by setting variable a dropping fraction of each iteration at 0.3. The overlapping methylation markers were then selected by the two methods for model building a binary prediction. A logistic regression model was fitted using these 9 markers as the covariates and obtained a combined diagnosis score (designated as cd-score) by multiplying the unbiased coefficient estimates and the marker methylation value matrix in both the training and validation datasets. The predictability of the model was evaluated by area under ROC (AUC, also known as C-index), which calculated the proportions of concordant pairs among all pairs of observations with 1.0 indicating a perfect prediction accuracy. Confusion tables were generated using an optimized cd-score cutoff with a maximum Youden's index.

[0370] The pre-treatment or initial methylation level was obtained at the initial diagnosis, and the post-treatment level was evaluated approximately 2 months after treatment, where the treatment referred to either chemotherapy or surgical resection of tumor. The primary endpoint (including response to treatment: progressive disease (PD), partial response (PR) and stable disease (SD)) was defined according to the RECIST guideline. For patients treated with surgical removal and no recurrence at time of evaluation, it was assumed that they had complete response (CR). The difference of cd-score distribution between clinical categories was examined by two- sided t-test as the cd-score was shown to be non-normally distributed using a Shapiro-Wilk Test.

[0371] Building a predictive model for prognosis and survival

[0372] The potential to use a combined prognosis score (cp-score) system for prediction of prognosis in CRC combination with clinical and demographic characteristics including age, gender, and AJCC stage was investigated. Tumor samples were selected from diagnosis' s training cohort as training data set, and the tumor samples from validation cohort as the validation data set. Variable selection was conducted on the training data set and built the composite score on the validation cohort. A univariate pre-screening procedure was first performed to remove excessive noise to facilitate the computational analysis, which is generally recommended prior to applying any variable selection method. A marker with p-value < 0.05 from the Wald statistic was retained in the dataset. Second, a similar subsampling strategy in a diagnosis marker selecting process based on LASSO-cox method was used to shrink the marker numbers to a reasonable range (less than events). Slightly different from the binary classifier, subsampling was carried out in the training dataset with replacement in case that the event proportion was too low for a model construction. The frequency cutoff was set as 50 to retain approximately 1/10th of total events. The above analysis generated 2 final markers to construct a prognostic signature (Table 14). The cp-score was then calculated from the linear predictor of multi variate Cox regression model with the 2 markers. A Kaplan-Meier curve and log-rank test were generated using the dichotomized cp-score, which formed a high-risk and low-risk group membership assignment according to its median. This segmentation was compatible with that formed by AJCC stage. Time-dependent ROC was used to summarize the discrimination potential of the cp-score, AJCC stage, CEA level, primary tumor location and the combination of all factors, with ROC curves varying as a function of time and accommodating censored data. Finally, a multivariate Cox regression model was fitted to assess the significance of potential risk factors.

[0373] All hypothesis testing in the prognostic analysis section were done by two-sided with p- value < 0.05 considered to be statistically significant. All the analysis was conducted in R version 3.4.3 with the following packages used: 'glmnet', 'pROC, 'limma', 'survival', 'survival ROC, 'survcomp'.

[0374] Unsupervised discovery of ctDNA methylation-based subtypes

[0375] Training dataset (n=528) was adopted to discover CRC groups/subtypes. Aiming to narrow down markers and get meaningful clustering by methylation information provided itself, an algorithm was used with iterative refinement of key features that was modified for better represents each cluster. This algorithm was modified as follows. Briefly, the markers were first filtered out with low variability using a threshold of median absolute deviation <0.5. The matrix was then adjusted by mean centering on markers and samples in training dataset. Secondly, an iterator procedure was used to classify and get a marker list for predicting subtypes: (i) Consensus Clustering was used to initially cluster the dataset and Cluster numbers was determined by relative change in area under CDF curve (ΔΑ, cutoff=0.05); (ii) Calculated centroid of each cluster and get correlation coefficient vector of each sample by multiply methylation matrix and centroid matrix, (iii) Re-cluster samples based on correlation coefficient vectors. The number of new clusters was determined by the maximum average silhouette width; (iv) Get differentially methylated markers among the new clusters by using a moderated F-test (from 'limnm package); Then feed the subset of matrix in terms of differential methylated markers into next iteration. The iteration stopped when differential methylated marker list did not change from the previous run and this marker set was finally used as subtype signature for predicting CRC subtypes.

[0376] Validation was performed on the predefined validation dataset (n=273). To get the subtype of validation samples, centroid methylation value of each cluster was first calculated with the methylation level of selected subtyping signature in the training dataset. Here, the centroid methylation value was defined as a representative methylation value of a cluster of samples by get mean value of signature across samples. Secondly, samples from validation cohort were assigned to clusters according to maximum Pearson correlation coefficient to each centroid value.

[0377] Cell-free DNA extraction from plasma samples

[0378] Plasma samples were frozen and preserved in at -80°C until use. 20,000 or more total unique reads per sample were observed to fulfilled this criterion, and in order to reliably produce >20,000 unique reads, a volume of 1.5ml or more plasma was required. This relationship between the amount of cfDNA in plasma and detected copy number was further accessed using digital droplet PCR. In addition, it was found that 1.5ml of plasma yielded > lOng of cfDNA, which produced at least 140 copies of detected amplicons in each digital droplet PCR assay. Based on these findings, 15 ng/1.5 ml was used as a cutoff to obtain reliable measurements of DNA methylation for all experiments in this study. For all cfDNA extractions, the EliteHealth cfDNA extraction Kit was used (EliteHealth, Guangzhou, China) according to the manufacturer's recommendations.

[0379] Bisulfite conversion of genomic or cfDNA

[0380] 10 ng of DNA was converted to bis-DNA using EZ DNA Methylation-Lightning™ Kit (Zymo Research) according to the manufacturer's protocol. Resulting bis-DNA had a size distribution of -200-3000 bp, with a peak around -500-1000 bp. The efficiency of bisulfite conversion was >99.8% as verified by deep-sequencing of bis-DNA and analyzing the ratio of C to T conversion of CH (non-CG) dinucleotides.

[0381] Determination of DNA methylation levels by deep sequencing of bis-DNA captured with molecular-inversion (padlock) probes [0382] In order to identify DNA sites with significantly different rates of methylation between CRC and normal blood, the variance was shrank using a t-statistic with Empirical Bayes36 and selected the top 1000 significant markers with the Benjamini-Hochberg procedure 37 controlling the FDR at a significance level of 0.05. CRC and normal blood were successfully distinguished by unsupervised hierarchical clustering of these top 1000 markers. 1,000 molecular

inversion (padlock) probes corresponding to these 1000 markers were then designed for capture- sequencing of cfDNA. Capture and sequencing were performed in bisulfite-converted cfDNA samples.

[0383] Probe design, synthesis and validation

[0384] All probes were designed using the ppDesigner software. The average length of the captured region was 100 bp, with the CpG marker located in the central portion of the captured region. Linker sequence between arms contained binding sequences for amplification primers separated by a variable stretch of Cs to produce probes of equal length. A 6-bp unique molecular identifier (UMI) sequence was incorporated in probe design to allow for the identification of unique individual molecular capture events and accurate scoring of DNA methylation levels. For capture experiments, probes were synthesized as separate oligonucleotides using standard commercial synthesis methods (IDT) and mixed in equimolar quantities, followed by purification using Qiagen columns.

[0385] There were significant differences between the number of reads captured by the most efficient probes and the non-efficient probes (60-65% of captured regions with coverage >0.2x of average) as shown by deep sequencing of the original pilot capture experiments. To ameliorate this, relative efficiencies were calculated from sequencing data and probes were mixed at adjusted molar ratios, which increased capture uniformity to 85% of regions at > 0.5x of average coverage.

[0386] Bis-DNA capture

[0387] To anneal probes to DNA, 10 ng of bisulfite-converted DNA was mixed with padlock probes in 20 μΐ reactions containing IX Ampligase buffer (Epicentre), followed by 30 second denaturation at 95°C was followed by a slow cooling to 55°C at a rate of 0.02°C per second. Hybridization was left to complete for 15 hrs at 55°C. To fill gaps between annealed arms, 5μ1 of the following mixture was added to each reaction: 2U of PfuTurboCx polymerase (Agilent), 0.5U of Ampligase (Epicentre) and 250 pmol of each dNTP in IX Ampligase buffer. After 5-hour incubation at 55°C, reactions were denatured for 2 minutes at 94°C. 5 μΐ of exonuclease mix (20U of Exo I and 100U of ExoIII, both from Epicentre) was added and single-stranded DNA degradation was carried out at 37°C for 2 hours, followed by enzyme inactivation for 2 minutes at 94°C. [0388] Circular products of site-specific capture were amplified by PCR with concomitant barcoding of separate samples. Amplification was carried out using primers specific to linker DNA within padlock probes, one of which contained specific 6bp barcodes. Both primers contained Illumina next-generation sequencing adaptor sequences. PCR was performed as follows: IX Phusion Flash Master Mix, 3 μΐ of captured DNA and 200nM primers, using the following cycle: 10s @ 98°C, 8X of (Is @ 98°C, 5s @ 58°C, 10s @ 72°C), 25X of (Is @ 98°C, 15s @ 72°C), 60s @ 72°C. PCR reactions were mixed and the resulting library was size selected to include effective captures (~230bp) and exclude "empty" captures (~150bp) using Agencourt AMPure XP beads (Beckman Coulter). Purity of the libraries was verified by PCR using Illumina flowcell adaptor primers (P5 and P7) and the concentrations were determined using Qubit dsDNA HS assay (Thermo Fisher). Libraries were sequenced using MiSeq and FIiSeq2500 systems (Illumina).

[0389] Optimization of capture coverage uniformity

[0390] Deep sequencing of the original pilot capture experiments showed significant differences between number of reads captured by most efficient probes and non-efficient probes (60-65% of captured regions with coverage >0.2x of average). To ameliorate this, relative efficiencies were calculated from sequencing data and probes were mixed at adjusted molar ratios. This increased capture uniformity to 85% of regions at > 0.2x of average coverage.

[0391] Sequencing data analysis

[0392] Mapping of sequencing reads was done using the software tool bisReadMapper with some modifications. First, UMI were extracted from each sequencing read and appended to read headers within FASTQ files using a custom script. Reads were on-the-fly converted as if all C were non-methylated and mapped to in-silico converted DNA strands of the human genome, also as if all C were non-methylated, using Bowtie2. Original reads were merged and filtered for single UMI, i.e. reads carrying the same UMI were discarded leaving a single, unique read. Methylation frequencies were calculated for all CpG dinucleotides contained within the regions captured by padlock probes by dividing the numbers of unique reads carrying a C at the interrogated position by the total number of reads covering the interrogated position.

[0393] Identification of Methylation Correlated Blocks (MCB)

[0394] In order to maximize the ability to measure small differences in DNA methylation advantage was taken of the notion that closely positioned CpG tend to have similar methylation levels, what is believed to be a result of the processivity and lack of sequence-specificity of DNA methyltransferases and demethylases, as well as the concept of haplotype blocks in genetic linkage analysis. Sequencing data was used to a generate MCB map using CRC and normal cfDNA samples. Pearson correlation coefficients between methylation frequencies of each pair of CpG markers separated by no more than 200bp were calculated separately across 50 cfDNA samples from each of the two diagnostic categories, e.g. normal blood and CRC. A value of Pearson's r < 0.5 was used to identify boundaries between adjacent markers with uncorrelated methylation. Markers not separated by a boundary were combined into Methylation Correlated Blocks (MCBs). This procedure identified a total of -1550 MCBs in each diagnostic category within the padlock data, combining between 2 and 22 CpG positions in each block. Methylation frequencies for entire MCBs were calculated by summing up the numbers of Cs at all interrogated CpG positions within a MCB and dividing by the total number of C+Ts at those positions.

[0395] Droplet digital PCR

[0396] The methylation status of cgl0673833 was determined for each of these samples using a droplet digital PCR paradigm featuring a Bio-Rad (Carlsbad, CA) QX-200 Droplet Reader and an Automated Droplet Generator (AutoDG). In brief, 10 ng of DNA from each subject was bisulfite converted using EZ DNA Methylation-Lightning™ Kit (Zymo Research). An aliquot of each sample was pre-amplified, diluted 1 :3,000, and then PCR amplified using fluorescent, dual labeled primer probe sets specific for cgl0673833 from Behavioral Diagnostics and Universal Digital PCR reagents and protocols from Bio-Rad. The number of droplets was determined using a QX-200 droplet counter and analyzed using QuantiSoft software. The results were expressed as a percent methylation. Reactions were excluded if fewer than 10,000 droplets were counted.

[0397] Patient and sample characteristics

[0398] The clinical characteristics and the methylation profiling of 459 CRC tumor samples were collected from The Cancer Genome Atlas (TCGA) and 754 normal samples from a dataset used in a previous methylation study on aging (GSE40279) to identify the CRC specific methylation markers. To study cfDNA in CRC, plasma samples were obtained from 801 Chinese patients with CRC, and from randomly selected, population-matched 1021 healthy controls undergoing routine health care maintenance (Fig. 31 A). Informed written consent was obtained from each participant. Clinical characteristics of all patients and controls are listed in Table 18.

[0399] A total of 1450 participants with high-risks of CRC were enrolled in the prospective screening cohort study and undergoing colonoscopy and cfDNA methylation test (Fig. 3 IB). Among them 18 participants were found to have colorectal cancer on colonoscopy (prevalence, 1.2%), 78 participants had advanced precancerous lesions (prevalence, 5.3%). Clinical characteristics of all participants from this cohort are listed in Table 19.

[0400] Identification of methylation markers differentiating CRC and blood

[0401] To identify putative markers that differentiate between CRC and normal blood samples, methylation data derived from CRC tissue DNA from the TCGA and normal blood were compared. The methylation data was obtained from 459 CRC and 754 blood samples from healthy controls. A "moderated t-statistic" analysis with Empirical Bayes for shrinking the variance was used and the top 1000 significant markers were selected by controlling the false discovery rate (FDR) at significance level 0.05 using the Benjamini-Hochberg procedure. The molecular-inversion (padlock) probes corresponding to these 1000 markers were designed for capture-sequencing cfDNA from plasma and 544 markers were selected with good experimental amplification profile and dynamic methylation range for further analysis. The genetic linkage disequilibrium (LD block) concept was used to study the degree of co-methylation among different DNA strands, with the underlying assumption that DNA sites in close proximity are more likely to be co-methylated than distant sites.

[0402] cfDNA diagnostic prediction model for CRC

[0403] The entire methylation dataset of 544 markers was analyzed by Least Absolute Shrinkage and Selection Operator (LASSO) and Random Forest to reduce the number of markers (Fig. 36). 801 CRC samples and 1021 normal control samples were randomly assigned to a training set and a validation set with a 2: 1 ratio (Fig. 32A). LASSO-based feature selection identified 13 markers and Random Forest-based feature selection identified 22 markers for discriminating CRC versus normal. There were 9 overlapping markers between these two methods (Table 13). A diagnostic prediction model was constructed with these 9 markers and a combined diagnostic score system (cd-score) was formulated according to the coefficients from the multinomial logistic regression. Applying this model, a high consistency was observed between predicted results and pathological diagnosis results in both the training dataset and validation dataset (Fig. 32B and 32C). The area of AUC was 0.96 (95%CI 0.95-0.97) in training dataset (Fig. 32D) and 0.96 (95%CI 0.94-0.97) in validation dataset (Fig. 32E) respectively. By using a best cutoff value determined via Youden index method, the model yielded a sensitivity of 87.5% and a specificity of 89.9% for discriminating CRC from normal controls in the training dataset and a sensitivity of 87.9% and a specificity of 89.6% in the validation dataset (Fig. 32G and 32H). While these results clearly demonstrated the potential of ctDNA methylation markers for predicting the presence of CRC.

[0404] The utility of the cd-score in assessing the staging of CRC was then examined, the presence of residual tumor after treatment, the response of treatment (such as surgery or chemotherapy). The cd-scores of patients with detectable residual tumor following treatment were significantly higher than those without detectable tumor (p=<0.001, Fig. 37A). Similarly, there was good correlation between the cd-scores and tumor stage. Patients with early stage disease (I, II) had substantially lower cd-scores compared to those with advanced stage disease (III, IV) (p=<0.001, Fig. 37B). Furthermore, the cd-scores were significantly higher in patients before treatment compared to those received surgery (p< 0.001, Fig. 37E). When the tumor recurrence, the cd-score increase again (Fig. 37E).

[0405] CEA has been used in diagnosis and surveillance of CRC for decades. But its sensitivity and specificity are not satisfied, which led to the necessity of invasive approaches, like colonoscopy, in most suspected CRC patients. In biopsy-proven CRC patients of the cohort, the cd-score demonstrated superior sensitivity and specificity to CEA for CRC diagnosis (AUC 0.96 vs 0.72, Fig. 37F). Both cd-score and CEA values were highly correlated with tumor stage (Fig. 37B and Fig. 37D). In patients with treatment response or tumor recurrence, the cd-score showed more significant changes from initial diagnosis than that of CEA (Fig. 37E and Fig. 37F).

[0406] cfDNA prognostic prediction model for CRC

[0407] Next the potential to use a combined prognosis score (cp-score) based on ctDNA methylation analysis was investigated for prediction of prognosis of CRC in combination with clinical and demographic characteristics including age, gender, primary tumor site and AJCC stage. Follow-up information of 801 CRC patients for prognostic score-based analysis was completed. The median follow-up times were 11.9 months (rang 0.5-25.7 months). The same training dataset as diagnosis section containing 528 observations with 73 events and validation dataset containing 273 observations with 32 events was applied. A variable selection was conducted on the training set and built the composite score on the validation set. UniCox and LASSO-Cox methods were implemented to reduce the dimensionality and constructed a Cox- model to predict prognosis with a two-markers panel (Fig. 33A and Table 14). A Kaplan-Meier curve and log-rank test were generated using the dichotomized composite score, which resulted in a high-risk and low-risk group membership assignment according to its median. Median survival time in low-risk group was significantly better than that in high-risk group (pO.001) (Fig. 33B and Fig. 33C).

[0408] Time-depended ROC was used to summarize the discrimination potential of the composite score, AJCC stage, CEA level, primary tumor location, and the combination of all the existing biomarkers. Multivariate Cox regression indicated that the cp-score significantly correlated with risk of death and was an independent risk factor of survival both in training set and validation set (Table 15). TNM stage (as defined by AJCC guidelines), CEA level, primary tumor location also predicted the 12-month survival of patients with CRC (Table 15).

Furthermore, the combination of cp-score and clinical characteristics improved the ability to predict prognosis (AUC 0.79, 95%CI 0.70-0.88 in training cohort and 0.85, 95%CI 0.75-0.96) in validation cohort) (Fig. 33D and Fig. 33E).

[0409] Nomograms create a simple graphical representation of a statistical predictive model that generates a numerical probability of a clinical event. It can reduce statistical predictive models into a single numerical estimate of the probability of death. Multivariate Cox regression analysis identified four variables as independent predictive factors (cp-score, CEA level, TNM stage and primary tumor location, Table 15) in both training and validation cohort. As such, a nomogram was developed with point scales of these 4 variables to predict overall survival for CRC patients (Fig. 34A). The sum of each variable point was plotted on the total point axis, and the estimated median 1- and 2-year overall survival rates were obtained by drawing a vertical line from the plotted total point axis straight down to the outcome axis. In validation cohort, the c- index of this model was 0.839, indicating a good discrimination. Fig. 34B showed the calibration graph for the nomogram, in which the probability of 1 -year overall survival as predicted by the nomogram is plotted against the corresponding observed survival rates obtained by the Kaplan - Meier method.

[0410] cfDNA methylation based subtyping of CRC

[0411] To generate a cfDNA methylation based subtypes of CRC, an unsupervised clustering method was utilized. The method applied an iteration strategy that iteratively got rid of markers had less contributions to the initial clusters (Fig. 35 A). Using the same training dataset as in building prognosis model, two clusters of CRC samples were obtained with a combined total of 45 markers that were differential methylated between clusters (Fig. 35B). From in silhouette analysis of the last round of iterations, a high separation distance was observed (Fig. 35C). The validation set was also classified by computing their correlation coefficients to centroid profile of clusters from training set.

[0412] The validation set was divided into two groups that shows a distinctly different methylation profile of the 45 markers (Fig. 35D). To explore the clinical relevance of the two subtypes, associations between the subtype and all available clinical factors including TNM stage, tumor site, MMR status, MSS status, tumor burden, sex, mutation status of a limited gene panels and survival outcomes were systematically tested. As a result, the second cluster in both training and validation data set have a significant poor survival rate than that of the first cluster (Fig. 35E, upper panel, both p<0.01, Log-rank Test). It was also found that the proportion of high stage CRC in cluster 2 were significantly higher than cluster 1 (Fig. 35E, lower panel, both p<0.05, Chi-squared Test). Considering the potential multicollinearity of the subtype and TNM stage in discriminating cohort with poor survival, multivariate cox regression analysis was performed and both factors were mutually independent for predicting overall survivals (Table 16).

[0413] The 45 markers for subtyping was classified into two groups according to the hypo- or hyper- methylation in clusters (27 hypo and 18 hyper in cluster 2, Table 20). Among these markers, three was also identified in the list of diagnosis markers and one was identified in both the diagnosis and prognosis marker lists (Fig. 38). Further analysis showed that cp-scores in cluster2 were significantly higher than cluster 1 in two datasets (Fig. 40B, p<0.001, Wilcox Test). Given that 7-45018848 was identified in the three separate marker lists and was shown to be hyper-methylated in cluster 2, its presence may contribute to the vary survival outcomes between the two subtypes. [0414] As CpG site cgl0673833 (7-45018848) was the only overlapping marker in diagnosis, prognosis, and molecular subtype analysis, the utility of cgl0673833 as a potential marker in monitoring treatment response was investigate. Serial longitudinal dynamic changes of methylation values of cgl0673833 were obtained in a group of CRC patients. The results showed that there was a high correlation between methylation values of cgl0673833 and treatment outcomes, which was greater than that observed for CEA (Fig. 39). In patients with serial samples, those with a positive treatment response had a concomitant and significant decrease in methylation values of cgl0673833 compared to that prior to treatment, and there was an even further reduction in methylation values of cgl0673833 in patients after surgery. In contrast, patients with progressive or recurrent disease had an increase methylation rate (Fig. 40).

[0415] Methylation markers for screening and early diagnosis of CRC in high-risk populations using 7-45018848

[0416] The potential of cgl0673833 as a methylation marker in detection of CRC and precancerous lesions in high-risk population based on plasma samples was investigated. From January 2015 through June 2017, 1450 participants who were recognized with high risks of CRC, were scheduled to undergo screening colonoscopy and methylation test of cgl0673833 (Fig. 3 IB).

[0417] Table 17 showed the screening results of colonoscopy and cgl0673833 methylation testing. cgl0673833 methylation testing identified 9/10 participants with CRC and 7/8 participants with CRC in situ, for sensitivity of 88.9% (95% CI, 0.74-1.00) and specificity of 86.5% (95% CI, 0.85-0.88). Positive predictive value (PPV) and negative predictive value (NPV) were 0.077 (95% CI, 0.041 to 0.113) and 0.998 (95% CI, 0.996-1.00) (Table 21), respectively For advanced precancerous lesions, the sensitivity was 33.3% (95% CI, 0.229-0.438), significant higher than the positivity rate for subjects without any pathology (12.3%, 95% CI, 0.106-0.141).

[0418] Table 13. Characteristics of night methylation markers and their coefficients in diagnosis.

MCBs Target ID Ref Gene Coefficients

Intersect -2.76

7-45018848 cgl0673833 MYOIG 15.98

1-161169007 cgl0493436 ADAMTS4 1.88

10-88684020 cgl0428836 BMPR1A -6.05

11-60738995 cg27284288 CD6 3.29

12-7276714 cgl6959747 RBP5 1.45

13-106834900 eg 17494199 Chr 13: 10 -2.24

14-55647474 cg23678254 LGAP5 2.71

6-16729606 cg24067911 ATXN1 -3.41

8-20375578 cg25459300 Chr 8:20 4.06 [0419] Table 14. Characteristics of two methylation markers and their coefficients in prognosis.

[0420] Table 15. Multi variable cox regression analysis with covariates including cp-score, gender, age, tumor location, TNM stage, CEA for overall survival.

[0421] Table 16. Association between cfDNA methylation based CRC subtypes and CRC prognosis in both the training and validation set (the same cohort as the prognosis model analysis).

[0422] Table 17. Sensitivity and Specificity of the ctDNA methylation test for the findings on colonoscopy.

Non-advanced

100 24 76 24.0 (15.6-32.2) 76.0 (0.68-0.84) adenoma

Polyps 250 20 230 8.0 (4.6-11.4) 92.0 (88.6-95.4)

Inflammatory

10 0 10 100 bowel disease

Negative on

994 123 871 87.6 (85.6- 89.7) colonoscopy

All non-advanced

adenoma, nonneoplastic finding,

1354 167 1187 87.7 (85.9-89.4) and negative

results on

colonoscopy

[0423] Table 18. Clinical characteristics of study cohort.

[0424] Table 19. Clinical characteristic of screening study cohort.

[0425] Table 20. Characteristics of 45 methylation markers in ctDNA methylation based subtyping of CRC.

Methylation

MCBs Target ID status Ref Gene

4-38673144 cg05205843 Hypo in cluster 1 KLF3

17-75539913 cgl 1841704 Hypo in cluster 1 NA

8-95651048 cg06699564 Hypo in cluster 1 NA

13-111160399 cg08924619 Hypo in cluster 1 COL4A2

1-57001742 cgl l959316 Hypo in cluster 1 PPAP2B

13-111160365 cg08924619 Hypo in cluster 1 COL4A2

8-95651086 cg06699564 Hypo in cluster 1 NA

17-75539901 cgO 1824933 Hypo in cluster 1 NA

13-111160418 cg08924619 Hypo in cluster 1 COL4A2

4-3867313 cg05205842 Hypo in cluster 1 KLF3

13-111160424 cg08924619 Hypo in cluster 1 COL4A2

17-48894963 cg04049981 Hypo in cluster 1 NA

1-15686708 cg09026722 Hypo in cluster 1 PEAR1

13-112602444 cg03616722 Hypo in cluster 1 NA

13-11116043 cg08924619 Hypo in cluster 1 COL4A2

17-16924597 cg05928904 Hypo in cluster 1 NA

3-194826585 cg08704934 Hypo in cluster 1 C3orfll

7-2150548 cg09776772 Hypo in cluster 1 MAD1L1

13-106834942 eg 17494199 Hypo in cluster 1 NA

17-75539895 cgO 1824933 Hypo in cluster 1 NA

8-126285443 cgl6296417 Hypo in cluster 1 NSMCE2

7-2150534 cg09776772 Hypo in cluster 1 MAD1L1

7-215055 cg09776772 Hypo in cluster 1 MAD1L1

15-68498251 cg05338167 Hypo in cluster 1 CALML4

1-161169007 cgl0493436 Hypo in cluster 1 ADAMTS4

13-112612344 cg011251410 Hypo in cluster 1 NA

15-58723675 cgl6391792 Hypo in cluster 1 UPC

6-31527889 cg06393830 Hyper in cluster 2 NA

2-113931518 cg09366118 Hyper in cluster 2 PSD4

3-118955835 cg22513455 Hyper in cluster 2 B4GALT4

8-129005567 cgl7583432 Hyper in cluster 2 PVT1

8-59058648 cg23881926 Hyper in cluster 2 F AM 110B

16-29757318 cg09638208 Hyper in cluster 2 C16orf54

17-55456535 cgl2441066 Hyper in cluster 2 MSI2

11-60738995 cg27284288 Hyper in cluster 2 CD6 10-14701815 _C g04441857 Hyper in cluster 2 FAM107B

8-129005599 cgl7583432 Hyper in cluster 2 PVT1

7-45018848 cgl0673833 Hyper in cluster 2 MYOIG

1-154128002 cgl9757176 Hyper in cluster 2 TPM3

19-1602335 cg08670281 Hyper in cluster 2 CYP4F11

8-129005583 cgl7583432 Hyper in cluster 2 PVT1

17-8370004 cg04460364 Hyper in cluster 2 NDEL1

12-7276714 cgl6959747 Hyper in cluster 2 RBP5

12-132269608 cgl5011734 Hyper in cluster 2 SFRS8

2-69027039 cg25754195 Hyper in cluster 2 ARHGAP25

[0426] Table 21. Positive and negative predictive values of cfDNA methylation test.

Negative

N of Positive Predictive

Outcome Predictive Value

participations Value (95% CI)

(95% CI)

0.077 (0.041-

Colorectal cancer 18/1450 0.998 (0.996-1.00)

0.113)

Advanced 0.134 (0.087- 0.042 (0.031-

78/1450

precancerous lesion 0.183) 0.053)

[0427] While preferred embodiments of the present disclosure have been shown and described herein, it will be obvious to those skilled in the art that such embodiments are provided by way of example only. Numerous variations, changes, and substitutions will now occur to those skilled in the art without departing from the disclosure. It should be understood that various alternatives to the embodiments of the disclosure described herein may be employed in practicing the disclosure. It is intended that the following claims define the scope of the disclosure and that methods and structures within the scope of these claims and their equivalents be covered thereby.

Table 1

cancer+normal)

(cancer vs cancer)

17- 11- cg2441250

cg04581327 (cancer+normal vs (cancer vs cancer)

17687239 13690194 1

cancer+normal)

(cancer vs cancer)

17- cgl808794

cg08108311 (cancer vs cancer) 11-2160540 (cancer+normal vs

40932746 3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cgl460815

cg23299262 (cancer+normal vs 11-2160554 (cancer+normal vs

40932983 6

cancer+normal) cancer+normal)

(cancer vs cancer)

17- cgl277332

cg09872233 (cancer vs cancer) 11-2160560 (cancer+normal vs

4544925 5

cancer+normal)

(cancer vs cancer)

17- cgl261402

cgl6495265 (cancer vs cancer) 11-2160564 (cancer+normal vs

46671010 9

cancer+normal)

(cancer vs cancer)

17- cg0071624

cg03809346 (cancer vs cancer) 11-555724 (cancer+normal vs

46671077 5

cancer+normal)

17- 11- cg2561857

cg05085809 (cancer vs cancer) (cancer vs cancer)

46671083 66034896 3

17- 11- cgl520141

cg06266993 (cancer vs cancer) (cancer vs cancer) 46671131 66034922 7

(cancer vs cancer)

17- 11- cg0257913

cgl 1155697 (cancer vs cancer) (cancer+normal vs

46671234 75917404 6

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 11- cg2340000

cg02712075 (cancer+normal vs (cancer+normal vs

46671244 75917724 2

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 11- cgl758344

cgl0153335 (cancer+normal vs

46671293 (normal vs normal) 75917844 9

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 12- cgl731656

cg02293936 (cancer+normal vs

46671298 (normal vs normal) 100557738 4

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 12- cg2018427

cg24626312 (cancer+normal vs (cancer+normal vs

46671332 14413090 1

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 12- cg0687231

cgl4126688 (cancer vs cancer) (cancer+normal vs

46671497 14413185 3

cancer+normal)

(cancer vs cancer)

17- 12- cg0075347

cg00698906 (cancer+normal vs (cancer vs cancer)

48619308 21810489 8

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) 12- cg2347161

cg27437806 (cancer+normal vs

48619672 (cancer+normal vs 98897216 2

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 13- cgl877135

cgl2791192 (cancer+normal vs (cancer vs cancer)

48619753 107186870 7

cancer+normal)

17- 13- cgl 117314

cgl9554255 (cancer vs cancer) (cancer vs cancer)

75369051 107187412 6

(cancer vs cancer)

17- (cancer vs cancer) 14- cg2341198

cgl6779463 (cancer+normal vs

75369055 (normal vs normal) 105940377 1

cancer+normal)

17- (cancer vs cancer) 14- cgl 172385

cgl7300544 (cancer vs cancer)

75369091 (normal vs normal) 24020053 0

(cancer vs cancer)

17- (cancer vs cancer) 14- cg2110719

cg03804136 (cancer+normal vs

75369219 (normal vs normal) 51027861 7

cancer+normal) (cancer vs cancer)

(cancer vs cancer)

17- 14- cg0639672

cgl4517217 (normal vs normal) (cancer vs cancer)

75447478 61188239 4

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- 15- cg0580422

cgl8104645 (normal vs normal) (cancer vs cancer)

75447504 45422062 0

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

17- 15- cgl556503

cg20955894 (cancer+normal vs (cancer vs cancer)

75447655 68871412 2

cancer+normal)

(cancer vs cancer)

17- 15- cg2080908

cgl l991516 (cancer+normal vs (cancer vs cancer)

75447785 72612221 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 15- cg0245489

cgl4697743 (cancer+normal vs (cancer+normal vs

75448089 90544015 0

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 15- cg2237519

cg07592976 (cancer+normal vs (cancer vs cancer)

8055733 99193466 2

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 16- cg0750629

cg23363911 (cancer vs cancer)

8055756 (cancer+normal vs 30389104 9

cancer+normal)

(cancer vs cancer)

17- 17- cg0255366

cgl4158601 (cancer+normal vs (cancer vs cancer)

8055831 80291775 3

cancer+normal)

(cancer vs cancer)

17- 18- cg0783666

cg21093368 (cancer+normal vs (cancer vs cancer)

8055834 12407797 1

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 19- cg0774941

cgl6545079 (cancer+normal vs (cancer+normal vs

8055888 10172825 2

cancer+normal) cancer+normal)

(cancer vs cancer)

19- 19- cg0690572

cg07614018 (cancer vs cancer) (cancer+normal vs

18811575 18210017 6

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- (cancer vs cancer) 19- cg0977777

cg21574675 (cancer+normal vs

45656942 (cancer+normal vs 24269890 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 19- cgO 100065

cg24122218 (cancer+normal vs (cancer+normal vs

45657270 24270468 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 19- cg2729785

cg05014211 (cancer+normal vs (cancer+normal vs

59074005 36389833 1

cancer+normal) cancer+normal)

(cancer vs cancer)

19- 19- cgl740989

cg08447733 (cancer+normal vs (cancer vs cancer)

59074308 42901325 3

cancer+normal)

(cancer vs cancer)

19- 19- cg2525321

cgl7735983 (cancer+normal vs (cancer vs cancer)

59074482 47776728 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 19- cgl503231

cg06458554 (cancer+normal vs (cancer+normal vs

9903777 50096610 4

cancer+normal) cancer+normal)

(cancer vs cancer)

2- 19- cg0666510

cg25160978 (cancer vs cancer) (cancer+normal vs

20866107 54369436 9

cancer+normal)

2- cg09150450 (cancer vs cancer) 19-6740812 cg2207697 (cancer vs cancer) 20866178 (cancer+normal vs 2 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cg21039778 cgl334172

20866231 (cancer+normal vs 19-6740888 (cancer+normal vs cancer+normal) 0

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl9113641 cg0370592

20866242 (cancer+normal vs 19-6740952 (cancer+normal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer)

2- 2- cgl2266953 cg2324688

20866261 (cancer+normal vs (cancer vs cancer)

202899877 5

cancer+normal)

2- (cancer vs cancer)

2- cg06168026 cg0816597

(cancer vs cancer)

45162196 233792394 (cancer+normal vs

1

cancer+normal)

2- (cancer vs cancer)

2- cg21236315 cg0682801

(cancer vs cancer)

45162467 233793120 (cancer+normal vs

5

cancer+normal)

20- (cancer vs cancer) (cancer vs cancer) cgl3544006 cgl018141

34189411 2-264120

(normal vs normal) (cancer+normal vs

9

cancer+normal)

(cancer vs cancer)

22- (cancer vs cancer)

cgl6590005 cg0346834

21319245 2-264164 (cancer vs cancer)

(cancer+normal vs 9

cancer+normal)

(cancer vs cancer)

22- cgl0348922 cg2182502

21319303 (cancer+normal vs 2-264166 (cancer vs cancer)

7

cancer+normal)

(cancer vs cancer)

22- (cancer vs cancer) (cancer vs cancer) cg07960806 cg2074974

21319661 2-264178

(cancer+normal vs (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

22- (cancer vs cancer) cgl 1782550 cg0010816

21319668 (cancer+normal vs 2-264199 (cancer+normal vs

4

cancer+normal) cancer+normal)

3- (cancer vs cancer) cg24954207 cg2594573

(cancer vs cancer)

128217091 2-264204 (cancer+normal vs

2

cancer+normal)

3- (cancer vs cancer) (cancer vs cancer) cgl0072850 cgl636751

187457732 (cancer+normal vs 2-74425523 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) cg05689600 cgl375554

125930496 (cancer+normal vs 2-74425580 (cancer+normal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer)

5- cg01814098 cg0986845

125930667 (cancer+normal vs 2-74425749 (cancer vs cancer)

1

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) cgl9551232 cg0796006

125931001 (cancer+normal vs 2-9144629 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer)

5- cg26327732 cg2036405

125931120 (cancer+normal vs 20-825240 (cancer vs cancer)

0

cancer+normal)

(cancer vs cancer)

5- cgl6738971 cg2035349

125931166 (cancer+normal vs 20-825268 (cancer vs cancer)

6

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) cgl3373406 cgl942426

151150340 (cancer+normal vs 20-825408 (cancer+normal vs

5

cancer+normal) cancer+normal)

5- (cancer vs cancer)

22- cg20775840 (cancer vs cancer) cg2548820

151150431 36236303 (cancer+normal vs

6

cancer+normal) (cancer vs cancer)

5- 3- cg0707454

cg00977110 (cancer+normal vs (cancer vs cancer)

151150581 119041529 3

cancer+normal)

(cancer vs cancer)

5- 3- cgl272737 (normal vs normal) cgl8375421 (cancer vs cancer)

157098338 183542914 4 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- 3- cgl915500

cg25959472 (cancer+normal vs (cancer+normal vs

171384415 183543564 7

cancer+normal) cancer+normal)

(cancer vs cancer)

5- 3- cg0973815 (normal vs normal) cgl8161950 (cancer vs cancer)

42995203 183543587 6 (cancer+normal vs cancer+normal)

5- 3- cgl034703

cgl4718568 (cancer vs cancer) (cancer vs cancer)

76011304 183543704 2

(cancer vs cancer)

5- 3- cg0303868

cgl4773260 (cancer vs cancer) (cancer+normal vs

76011323 197281468 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 3- cg0379276

cg04067276 (cancer+normal vs (cancer+normal vs

106958303 197281934 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- (normal vs normal) cg2472211

cg23413349 3-49757016 (cancer+normal vs

106958388 (cancer+normal vs 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- cg2575510

cg09184502 (cancer+normal vs 3-49757239 (cancer+normal vs

106958474 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- cg0443259

cg25944720 (cancer+normal vs 3-49757306 (cancer+normal vs

106958640 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 5- cgl412649

cg22231056 (cancer+normal vs (cancer+normal vs

106958645 176831297 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 5- cg0587686

cgO 1742627 (cancer+normal vs (cancer+normal vs

28911468 176831638 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 6- cg0059003

cg05127899 (cancer+normal vs (cancer+normal vs

28911474 158957433 6

cancer+normal) cancer+normal)

(cancer vs cancer)

6- cgl 106834

cg23326313 (cancer+normal vs 6-24360304 (cancer vs cancer)

28911759 3

cancer+normal)

(cancer vs cancer)

6- cg0703641

cgl5088539 (cancer+normal vs 6-24360391 (cancer vs cancer)

28911926 2

cancer+normal)

(cancer vs cancer)

6- cgl722512 (cancer vs cancer) cgl7372996 (cancer+normal vs 6-33244755

28921469 9 (normal vs normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- cg2599868

cg08827322 (cancer+normal vs 6-43044239 (cancer+normal vs

28921485 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- cg2166358

cg09633604 (cancer+normal vs 6-43044771 (cancer+normal vs

28921499 0

cancer+normal) cancer+normal) cgl923667

7-193262 cg08782337 (cancer vs cancer) 7-76624761 (cancer vs cancer)

5

(cancer vs cancer)

7- 8- cg0165751

cgl4428815 (cancer+normal vs (cancer vs cancer)

65878911 142318170 1

cancer+normal) (cancer vs cancer) cg0222786

8-1949246 cg09689137 (cancer vs cancer) 8-22457446 (cancer+normal vs

7

cancer+normal)

(cancer vs cancer)

9- cgl415312

8-1949342 cg25021970 (cancer vs cancer) (cancer+normal vs

131219302 6

cancer+normal)

Status - Hypo Status - Hypo

(cancer vs cancer) cgl288811

1-1358109 cgl2286462 (cancer vs cancer) 1-11107048 (cancer+normal vs

3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 1- cg2446133

cgl6908552 (cancer+normal vs (cancer+normal vs

231174153 167882440 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 1- cg2685966

cgl l811391 (cancer+normal vs (cancer+normal vs

23520083 167883298 6

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 1- cg2577816

cg09809672 (cancer vs cancer) (cancer+normal vs

236557682 171059935 6

cancer+normal)

(normal vs normal) (normal vs normal)

1- (cancer vs cancer) 1- cgl806314 (cancer vs cancer) cgl3187885

246930969 (cancer+normal vs 171060071 9 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

1- cgl733065

1-6134338 cg24446610 (cancer vs cancer) (cancer+normal vs

173886454 2

cancer+normal)

(cancer vs cancer)

1- cgl759157

1-7180862 cg09148344 (cancer vs cancer) (cancer+normal vs

179059407 4

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg2233227

1-8384659 cgl0508347 (cancer+normal vs (cancer+normal vs

207277018 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 1- cgl 115396

cgl8396714 (cancer+normal vs (cancer+normal vs

95289024 207277031 9

cancer+normal) cancer+normal)

10- 1- cg0263168

cg04819048 (cancer vs cancer) (cancer vs cancer) 14014548 209406266 4

(cancer vs cancer) (cancer vs cancer)

10- 1- cg2364637

cg23033014 (cancer+normal vs (cancer+normal vs

43849970 209847618 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 1- cg0491883

cgO 1275661 (cancer+normal vs (cancer+normal vs

5504438 241795170 1

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer) 1- cg0156529

cg20459238 (cancer vs cancer)

88719950 (cancer+normal vs 245812674 1

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cg2193267

cg08547848 (cancer+normal vs 1-95584445 (cancer+normal vs

102339610 2

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 10- cgl411532

cgl7256234 (cancer+normal vs (cancer vs cancer)

111311280 128275008 5

cancer+normal)

(cancer vs cancer)

11- cg0499297

cgl4849140 (cancer+normal vs 10-1334207 (cancer vs cancer)

4010752 4

cancer+normal)

(normal vs normal)

11- (cancer vs cancer) cg0676438

cg03614381 10-1576684 (cancer vs cancer)

71229642 (cancer+normal vs 7

cancer+normal)

12- cg21575634 (cancer vs cancer) 10-1714535 cg2498004 (cancer vs cancer) 131310417 0

12- cgl687333

cgl 1243173 (cancer vs cancer) 10-4500136 (cancer vs cancer)

23999045 4

(cancer vs cancer) (normal vs normal)

12- (cancer vs cancer) cgl 187504 (cancer vs cancer) cgl8436898 10-8546509

47471907 (cancer+normal vs 4 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 10- cg2428852

cg00015699 (cancer+normal vs (cancer+normal vs

90313589 93390347 7

cancer+normal) cancer+normal)

(cancer vs cancer)

12- 11- cg0336713

cg20490773 (cancer+normal vs (cancer vs cancer)

90313611 102638470 6

cancer+normal)

13- 11- cgl435012

cg08405286 (cancer vs cancer) (cancer vs cancer) 113301717 13700098 0

(cancer vs cancer) (cancer vs cancer)

13- 11- cg0037119

cg22612590 (cancer+normal vs (cancer+normal vs

114187973 46740481 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- 11- cg2645336

cgl3241681 (cancer+normal vs (cancer+normal vs 114187990 46741373 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- 11- cg0900469

cg20539175 (cancer+normal vs (cancer+normal vs 114188051 46741405 1

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

15- cgl416459

cg22423363 (cancer vs cancer) 11-6462110 (cancer+normal vs

65042722 6

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal) (normal vs normal)

16- (cancer vs cancer) 12- cgl063549 (cancer vs cancer) cg27316811

1576146 (cancer+normal vs 69199037 4 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

16- 15- cg0331008

cg27587310 (cancer+normal vs (cancer vs cancer)

29204994 99427016 7

cancer+normal)

(cancer vs cancer)

16- 16- cg0887925

cg02705762 (cancer vs cancer) (cancer+normal vs

51197459 20709238 5

cancer+normal)

(cancer vs cancer)

16- 16- cg0564099

cg02576153 (cancer vs cancer) (cancer+normal vs

85289758 87970367 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 16- cg0355086

cg07564598 (cancer+normal vs (cancer+normal vs

25619946 87970376 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 17- cgl853612

cg25504605 (cancer+normal vs (cancer+normal vs

56569119 26694939 3

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- (cancer vs cancer) 17- cgl660873

cg02746913 (cancer+normal vs

75237550 (cancer+normal vs 27370988 1

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- cg2480207

17-767301 cgl3476078 (cancer vs cancer) (cancer vs cancer)

39344868 8

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer) 17- cgl972078

17-767334 cg25236028 (cancer vs cancer)

(cancer+normal vs 51900887 0

cancer+normal) (cancer vs cancer) (cancer vs cancer) cgl896495

17-767380 cgl3120258 (cancer+normal vs 17-7019284 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 17- cgl691654

cg07724971 (cancer+normal vs (cancer vs cancer)

78035629 71547405 9

cancer+normal)

18- 18- cg0271419

cgl2931591 (cancer vs cancer) (cancer vs cancer)

3411821 77201972 2

(cancer vs cancer)

(cancer vs cancer)

19- (cancer vs cancer) 19- cg2743618

cgl9338222 (cancer+normal vs

39052032 (cancer+normal vs 45449006 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 2- cg2304141

cgl9786121 (cancer+normal vs (cancer+normal vs

39084308 113884447 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- cg2611245

cgl8668041 (cancer+normal vs 2-21267334 (cancer+normal vs

41190396 7

cancer+normal) cancer+normal)

(cancer vs cancer)

19- 2- cg0443764

cg21798669 (cancer vs cancer) (cancer+normal vs

8669959 234627450 8

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- cg2092672

cgl 1745755 (cancer+normal vs 2-44065725 (cancer+normal vs

8670086 0

cancer+normal) cancer+normal)

(cancer vs cancer)

2- cgl912333

cgl5153684 (cancer vs cancer) 2-44066294 (cancer+normal vs

10686963 9

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- (cancer vs cancer) cg0076027

cg23212579 2-44067042 (cancer+normal vs

219256018 (cancer+normal vs 2

cancer+normal) cancer+normal)

(cancer vs cancer)

2- cg0791993

cgl6926316 (cancer+normal vs 2-451875 (cancer vs cancer)

219256101 6

cancer+normal)

(cancer vs cancer)

2- cg0827905

cgl0397934 (cancer+normal vs 2-46707678 (cancer vs cancer)

242868376 5

cancer+normal)

2- cgl 157360

cgl3279009 (cancer vs cancer) 2-503193 (cancer vs cancer)

24584023 8

(cancer vs cancer)

2- cg0323013

cg20422417 (cancer+normal vs 2-60812640 (cancer vs cancer)

25427108 3

cancer+normal)

2- 20- cg2604261

cg22493364 (cancer vs cancer) (cancer vs cancer)

68672750 56227286 8

(cancer vs cancer)

(cancer vs cancer)

2- (cancer vs cancer) 21- cgl531016

cgl 1672772 (cancer+normal vs

75078286 (cancer+normal vs 37852822 2

cancer+normal) cancer+normal)

(cancer vs cancer)

2- 21- cg0441314

cg22037978 (cancer vs cancer) (cancer+normal vs

84517763 47575134 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- 22- cg0963446

cg24560809 (cancer+normal vs (cancer+normal vs

95939339 21128411 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- 22- cg0403358

cgl6208206 (cancer+normal vs (cancer+normal vs

31446363 24891666 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- 22- cgl865948

cg04772817 (cancer+normal vs (cancer+normal vs

32316843 41630982 3

cancer+normal) cancer+normal)

20- cg24332577 (cancer vs cancer) 22- cg0736655 (cancer vs cancer)

- I l l - 50419248 (cancer+normal vs 50644468 3 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- 22- cg2187486

cgl2288473 (cancer+normal vs (cancer+normal vs 50419274 50644682 2

cancer+normal) cancer+normal)

(cancer vs cancer)

20- 22- cg2593470

cgl0941835 (cancer vs cancer) (cancer+normal vs 50419348 50644755 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- 3- cg2630168

cg25169524 (cancer+normal vs (cancer+normal vs

56076737 142681704 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- cg2138018

cgl 1853697 (cancer+normal vs 4-1198278 (cancer+normal vs 60510235 1

cancer+normal) cancer+normal)

21- (cancer vs cancer) cgl689502

cg27019201 4-30745743 (cancer vs cancer)

46323665 (cancer vs cancer) 6

(cancer vs cancer)

21- cgl506369

cgl3180920 (cancer+normal vs 4-80329483 (cancer vs cancer)

46896174 5

cancer+normal)

21- cg2622648

cg25390243 (cancer vs cancer) 4-80329486 (cancer vs cancer)

46912506 7

(cancer vs cancer) (cancer vs cancer)

3- 5- cgl961680

cgl6827534 (cancer+normal vs (cancer+normal vs

12332780 139939823 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- 5- cg0418286

cg03513893 (cancer+normal vs (cancer+normal vs

184052502 141346431 5

cancer+normal) cancer+normal)

(cancer vs cancer)

3- 5- cg0120491

cgl4584085 (cancer vs cancer) (cancer+normal vs

186559147 142187317 1

cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) cgl285213

cgl0985281 5-16794882 (cancer vs cancer)

194573301 (cancer+normal vs 9

cancer+normal)

(cancer vs cancer)

3- cg2094189

cg07206256 (cancer+normal vs 5-17147858 (cancer vs cancer)

194573323 4

cancer+normal)

3- cg0186029

cg01451880 (cancer vs cancer) 5-17275783 (cancer vs cancer)

45801044 7

(cancer vs cancer)

4- 5- cg0662576

cgl5844438 (cancer vs cancer) (cancer+normal vs

140969039 176836695 7

cancer+normal)

(cancer vs cancer)

4- 5- cg0665160

cg06775361 (cancer+normal vs (cancer vs cancer)

141188341 178209759 5

cancer+normal)

(cancer vs cancer)

cg2194474

4-3480656 cgl3455623 (cancer+normal vs 5-4644304 (cancer vs cancer)

0

cancer+normal)

(cancer vs cancer)

5- 6- cgl351786 (normal vs normal) cgl8114890 (cancer+normal vs

180219707 168970787 6 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

cg0981716

5-9557609 cg23920603 (cancer+normal vs 6-27185676 (cancer vs cancer)

2

cancer+normal)

(cancer vs cancer)

6- cgl812697 (normal vs normal) cgl7356964 (cancer+normal vs 6-29588988

106582638 8 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cg2543780

cg25581448 6-29589545 (cancer vs cancer)

106582669 (cancer+normal vs 7

cancer+normal) (cancer vs cancer)

6- (cancer vs cancer) cg0137308

cg03329755 6-29589631 (cancer vs cancer)

167189272 (cancer+normal vs 9

cancer+normal)

6- (cancer vs cancer) cgl707194

cgl0896609 6-29590143 (cancer vs cancer)

168594903 (cancer vs cancer) 8

(cancer vs cancer)

6- cg0378112

cg05418218 (cancer vs cancer) 6-30168380 (cancer+normal vs

168613308 3

cancer+normal)

(cancer vs cancer)

6- cgl438984

cg23221431 (cancer+normal vs 6-72298704 (cancer vs cancer)

18368796 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- cg0392353

cgl4645856 (cancer+normal vs 7-1197113 (cancer+normal vs

18368844 5

cancer+normal) cancer+normal)

(cancer vs cancer)

6- cgl908611

cg23562023 (cancer+normal vs 7-20269648 (cancer vs cancer)

24429162 0

cancer+normal)

6- cgl310630

cgl8572200 (cancer vs cancer) 7-2959105 (cancer vs cancer)

32112546 6

6- cg0683044

cg05745748 (cancer vs cancer) 7-2959121 (cancer vs cancer)

33996013 1

6- cg0552968

cgl8434367 (cancer vs cancer) 7-3849359 (cancer vs cancer)

45891455 6

(cancer vs cancer)

6- (cancer vs cancer) cg0460984

cg21552001 7-4012372 (cancer vs cancer)

47202394 (cancer+normal vs 1

cancer+normal)

cgl717620

7-143220 cgl9755314 (cancer vs cancer) 7-4014070 (cancer vs cancer)

9

7- cg2105393

cg24251111 (cancer vs cancer) 7-4030038 (cancer vs cancer)

151553819 5

(cancer vs cancer)

7- cg0435883

cg23730037 (cancer+normal vs 7-4030413 (cancer vs cancer)

158596552 4

cancer+normal)

(cancer vs cancer)

cg0131060

7-170692 cgl9210140 (cancer+normal vs 7-4118609 (cancer vs cancer)

5

cancer+normal)

(cancer vs cancer)

cgl959605

7-1932321 cg23618217 (cancer+normal vs 7-42446248 (cancer vs cancer)

0

cancer+normal)

(cancer vs cancer) (cancer vs cancer) cgl555699

7-1961869 cgl5997393 (cancer+normal vs 7-80544479 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) cg0426412

7-210075 cgl2458039 7-80682238 (cancer vs cancer)

(cancer+normal vs 9

cancer+normal)

7- cg0364498

cgl9588408 (cancer vs cancer) 7-82286378 (cancer vs cancer)

28848902 4

(cancer vs cancer)

7- cg2515137

cgl9559984 (cancer vs cancer) 7-895646 (cancer+normal vs

28848933 6

cancer+normal)

(cancer vs cancer)

7- cg0419303

cgl2570246 (cancer vs cancer) 7-99637061 (cancer+normal vs

36959356 7

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

8- 8- cg0097136

cg01886570 (cancer vs cancer) (cancer+normal vs

123966105 142263802 9

(cancer+normal vs cancer+normal) cancer+normal) 8- cg2561179

cg21287347 (cancer vs cancer) 8-61086268 (cancer vs cancer)

59259110 6

9- cgl463326

9-4294020 cgl3573115 (cancer vs cancer) (cancer vs cancer)

135393396 8

(cancer+normal vs (cancer+normal vs

cancer+normal) cancer+normal)

Status - Hyper Status - Hyper

(cancer vs cancer)

1- (cancer+normal vs 1- cgl242047

cgl9602452 (cancer+normal vs

152943306 cancer+normal) 145395607 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- 1- cgl795266 (normal vs normal) cg23053573 (cancer+normal vs

26662567 145395753 1 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 1- cg0239536

cg22042546 (cancer+normal vs (cancer+normal vs

27050491 145395846 3

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

1- 1- cg2196120

cg04933208 (cancer+normal vs (cancer+normal vs

29586414 145455384 2

cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 1- cg2352034

cg26884027 (cancer+normal vs

29586418 cancer+normal) 206730839 7

cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs cgl721647

cg02852174 1-21616619 (cancer+normal vs

46782408 cancer+normal) 8

cancer+normal)

(cancer+normal vs

(cancer vs cancer)

10- cancer+normal) cg0681920

cg05676341 1-21616641 (cancer+normal vs

135206831 (cancer+normal vs 0

cancer+normal) cancer+normal)

(cancer vs cancer)

10- cg2024279 (cancer+normal vs cgl5900657 (cancer+normal vs 1-24645853

22518317 7 cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer+normal vs cg2128928

cg20822818 1-24645885 (cancer+normal vs

119235062 cancer+normal) 0

cancer+normal)

11- (cancer+normal vs cg0455250 (cancer+normal vs cg02565993 1-24645917

27015592 cancer+normal) 0 cancer+normal)

(cancer vs cancer)

11- cgO 100203 (cancer+normal vs cg09017174 (cancer+normal vs 1-65211677

35440525 0 cancer+normal) cancer+normal)

12- (cancer+normal vs 10- cgl607111 (cancer+normal vs cg06875424

114834713 cancer+normal) 106028543 8 cancer+normal)

12- (cancer+normal vs 10- cgl846276 (cancer+normal vs cg04562909

114836014 cancer+normal) 76584710 4 cancer+normal)

(normal vs normal) (cancer vs cancer)

12- 10- cg0620743

cg23820885 (cancer+normal vs (cancer+normal vs 114840942 97804280 2

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer+normal vs cgl808794

cg04685570 11-2160540 (cancer+normal vs 114841202 cancer+normal) 3

cancer+normal)

(cancer vs cancer)

12- (cancer+normal vs cgl460815

cg22045225 11-2160554 (cancer+normal vs

114841792 cancer+normal) 6

cancer+normal)

(normal vs normal) (cancer vs cancer)

12- cgl277332

cgl2437821 (cancer+normal vs 11-2160560 (cancer+normal vs

114852027 5

cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer+normal vs cgl261402

cgl0488031 11-2160564 (cancer+normal vs 110437561 cancer+normal) 9

cancer+normal)

15- cg06650067 (cancer+normal vs 11-2160904 cgl900233 (cancer+normal vs 66084924 cancer+normal) 7 cancer+normal)

16- (cancer+normal vs cg2436665 (cancer+normal vs cg02331262 11-2160932

87988631 cancer+normal) 7 cancer+normal)

16- (cancer+normal vs cg0411201 (cancer+normal vs cgl0499753 11-2165136

89654085 cancer+normal) 9 cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) cg0071624

cg25927164 11-555724 (cancer+normal vs

17685407 (cancer+normal vs 5

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 11- cg0352266 (cancer+normal vs cgl5906409

17685582 (cancer+normal vs 68780866 8 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

17- 11- cg0257913

cgl9872299 (normal vs normal) (cancer+normal vs 17686141 75917404 6

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 11- cg2340000

cg01743962 (cancer+normal vs (cancer+normal vs

17686332 75917724 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 11- cgl758344

cg04581327 (cancer+normal vs (cancer+normal vs

17687239 75917844 9

cancer+normal) cancer+normal)

17- (cancer+normal vs 11- cgl062486 (cancer+normal vs cgl0415767

17726759 cancer+normal) 75945841 0 cancer+normal)

(cancer vs cancer)

17- (cancer+normal vs 12- cgl731656

cg23103688 (cancer+normal vs

40932953 cancer+normal) 100557738 4

cancer+normal)

(cancer vs cancer)

17- 12- cg0180548 (cancer+normal vs cg23299262 (cancer+normal vs

40932983 133137879 0 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 12- cg2018427

cg02712075 (cancer+normal vs (cancer+normal vs

46671244 14413090 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 12- cg0687231

cg24626312 (cancer+normal vs (cancer+normal vs

46671332 14413185 3

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 12- cg0258419 (cancer+normal vs cg00698906 (cancer+normal vs

48619308 98897187 3 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) 12- cg2347161

cg27437806 (cancer+normal vs

48619672 (cancer+normal vs 98897216 2

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 13- cgl236854 (cancer+normal vs cgl2791192 (cancer+normal vs

48619753 50570250 2 cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer+normal vs 14- cg2341198

cgl8783374 (cancer+normal vs

55474945 cancer+normal) 105940377 1

cancer+normal)

(cancer vs cancer)

17- (cancer+normal vs 14- cg2110719

cg00691729 (cancer+normal vs

58468300 cancer+normal) 51027861 7

cancer+normal)

17- (cancer+normal vs 15- cg0500938 (cancer+normal vs cgl8673401

68166021 cancer+normal) 90208810 9 cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- 15- cg2670366 (cancer+normal vs cgl4517217 (normal vs normal)

75447478 90208915 1 cancer+normal)

(cancer+normal vs

cancer+normal) (cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

17- 15- cg0245489

cgl8104645 (normal vs normal) (cancer+normal vs

75447504 90544015 0

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

17- 16- cg0423297 (cancer+normal vs cg20955894 (cancer+normal vs

75447655 30671644 2 cancer+normal) cancer+normal)

(cancer vs cancer)

17- 16- _C g0447778 (cancer+normal vs cgl l991516 (cancer+normal vs

75447785 30935822 9 cancer+normal) cancer+normal)

(cancer vs cancer)

17- 16- cgl396927 (cancer+normal vs cgl4697743 (cancer+normal vs

75448089 69760564 3 cancer+normal) cancer+normal)

(cancer vs cancer)

17- 17- cg2071793 (cancer+normal vs cg07592976 (cancer+normal vs

8055733 38226278 2 cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 19- cg0231705 (cancer+normal vs cg23363911

8055756 (cancer+normal vs 10172712 5 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 19- cg0774941

cgl4158601 (cancer+normal vs (cancer+normal vs

8055831 10172825 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 19- cg0690572

cg21093368 (cancer+normal vs (cancer+normal vs

8055834 18210017 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 19- cg0977777

cgl6545079 (cancer+normal vs (cancer+normal vs

8055888 24269890 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- (cancer vs cancer) 19- cgO 100065

cg21574675 (cancer+normal vs

45656942 (cancer+normal vs 24270468 7

cancer+normal) cancer+normal)

(cancer vs cancer)

19- 19- cgl870166 (cancer+normal vs cg24122218 (cancer+normal vs

45657270 34012935 0 cancer+normal) cancer+normal)

(cancer vs cancer)

19- 19- cg0775957 (cancer+normal vs cg05014211 (cancer+normal vs

59074005 35491951 0 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 19- cg2729785

cg08447733 (cancer+normal vs (cancer+normal vs

59074308 36389833 1

cancer+normal) cancer+normal)

(cancer vs cancer)

19- 19- cg2222046 (cancer+normal vs cgl7735983 (cancer+normal vs

59074482 42806228 7 cancer+normal) cancer+normal)

(cancer vs cancer)

19- 19- cg0927631 (cancer+normal vs cg06458554 (cancer+normal vs

9903777 47614071 5 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) - 19- cgl503231

cg09150450 (cancer+normal vs (cancer+normal vs

20866178 50096610 4

cancer+normal) cancer+normal)

(cancer vs cancer)

- 19- cgl502238 (cancer+normal vs cg21039778 (cancer+normal vs

20866231 50096791 7 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) - 19- cg0666510

cgl9113641 (cancer+normal vs (cancer+normal vs

20866242 54369436 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) - cg2207697

cgl2266953 (cancer+normal vs 19-6740812 (cancer+normal vs

20866261 2

cancer+normal) cancer+normal) (cancer vs cancer)

(cancer+normal vs cgl334172

2-9549336 cg09734418 19-6740888 (cancer+normal vs cancer+normal) 0

cancer+normal)

(cancer vs cancer)

21- (cancer+normal vs cg0370592

cgl 1388866 19-6740952

40752116 (cancer+normal vs cancer+normal) 6

cancer+normal)

(cancer vs cancer)

22- (cancer vs cancer) 2- cgl328369

cgl6590005 (cancer+normal vs 21319245 (cancer+normal vs 197852904 1 cancer+normal) cancer+normal)

(cancer vs cancer)

22- 2- cg0177811

Cgl0348922 (cancer+normal vs

(cancer+normal vs

21319303 216877947 4 cancer+normal) cancer+normal)

(cancer vs cancer)

22- (cancer vs cancer)

(cancer vs cancer) 2- cg0816597

Cg07960806

21319661 (cancer+normal vs

(cancer+normal vs 233792394 1

cancer+normal) cancer+normal)

(cancer vs cancer)

22- (cancer vs cancer)

2- cg0682801

Cgl 1782550 (cancer+normal vs

21319668 (cancer+normal vs

233793120 5

cancer+normal) cancer+normal)

22- (cancer vs cancer)

(cancer+normal vs cgl018141

Cgl5907944 2-264120

27152698 (cancer+normal vs cancer+normal) 9

cancer+normal)

3- (cancer vs cancer)

(cancer+normal vs cg2074974

Cg04599356 2-264178

181436643 (cancer+normal vs cancer+normal) 1

cancer+normal)

3- (cancer vs cancer)

(cancer+normal vs cg0010816

Cgl3483916 2-264199

187456579 (cancer+normal vs cancer+normal) 4

cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) cg2594573

Cgl0072850 (cancer+normal vs 2-264204

187457732 (cancer+normal vs

2

cancer+normal) cancer+normal)

(normal vs normal)

4- (cancer vs cancer) cgl636751

Cg06374962 (cancer+normal vs 2-74425523

111531926 (cancer+normal vs

1

cancer+normal) cancer+normal)

(normal vs normal)

4- (cancer vs cancer) cgl375554

Cgl8064927 (cancer+normal vs 2-74425580

111531975 (cancer+normal vs

6

cancer+normal) cancer+normal)

(normal vs normal)

4- cgl531182

cg22006640 (cancer+normal vs

(cancer+normal vs 2-9144618

111532035 2 cancer+normal) cancer+normal)

(normal vs normal)

4- (cancer vs cancer) cg0796006

cgl 1416290 (cancer+normal vs 2-9144629

111532410 (cancer+normal vs

7

cancer+normal) cancer+normal)

5- (cancer+normal vs 20- cg0585253

cg08755283 (cancer+normal vs

118324104 cancer+normal) 33759753 7 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- cgl 942426

cg05689600 (cancer+normal vs 20-825408

125930496 (cancer+normal vs

5

cancer+normal) cancer+normal)

(cancer vs cancer)

5- cgl485529

cg01814098 (cancer+normal vs

(cancer+normal vs 20-825415

125930667 2 cancer+normal) cancer+normal)

(cancer vs cancer)

5- 22- cg0113865

cgl9551232 (cancer+normal vs

(cancer+normal vs

125931001 19973978 2 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- 22- cg2548820

cg26327732 (cancer+normal vs

125931120 (cancer+normal vs

36236303 6

cancer+normal) cancer+normal)

(cancer vs cancer)

5- 3- cg0589497

cgl6738971 (cancer+normal vs

(cancer+normal vs

125931166 119041204 0 cancer+normal) cancer+normal) (cancer vs cancer)

(cancer vs cancer)

5- 3- cgl272737 (normal vs normal) cgl3373406 (cancer+normal vs

151150340 183542914 4

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- 3- cgl915500

cg00977110 (cancer+normal vs

151150581 (cancer+normal vs

183543564 7

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- 3- cg0973815

cg25959472 (normal vs normal)

(cancer+normal vs

171384415 183543587 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer)

3- cg04067276 cg0303868

(cancer+normal vs

106958303 (cancer+normal vs

197281468 5

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer)

(normal vs normal) 3- cg23413349 cg0379276

106958388 (cancer+normal vs

(cancer+normal vs 197281934 8

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cg2472211

cg09184502 (cancer+normal vs 3-49757016

106958474 (cancer+normal vs

2

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cg2575510

cg25944720 (cancer+normal vs 3-49757239

106958640 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cg0443259

cg22231056 (cancer+normal vs 3-49757306

106958645 (cancer+normal vs

7

cancer+normal) cancer+normal)

6- (cancer+normal vs

cg23603995 cg0223106 (cancer+normal vs

3-52567130

157198648 cancer+normal) 6 cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cg01742627 5- cgl412649

(cancer+normal vs

28911468 (cancer+normal vs

176831297

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cg05127899 5- cg0587686

(cancer+normal vs

28911474 (cancer+normal vs

176831638 4

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer)

6- cg23326313 cg0059003

28911759 (cancer+normal vs

158957433 6 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

6- cgl5088539 cg2709890 (cancer+normal vs

(cancer+normal vs 6-33245128

28911926 0 cancer+normal) cancer+normal)

(cancer vs cancer)

6- cgl 177291 (cancer+normal vs cgl7372996 (cancer+normal vs 6-33245328

28921469 9

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cg2599868

cg08827322 (cancer+normal vs 6-43044239

28921485 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

6- cg0933265

cg09633604 (cancer+normal vs

(cancer+normal vs 6-43044537

28921499 5 cancer+normal) cancer+normal)

7- (cancer vs cancer)

(cancer+normal vs cg2166358

cgl0436877 6-43044771

150924351 (cancer+normal vs cancer+normal) 0

cancer+normal)

7- cg07671603 (cancer+normal vs cg2503376

6-43044876 (cancer+normal vs

156433350 cancer+normal) 7 cancer+normal)

(normal vs normal)

7- 8- cgl 168827

cg22051964 (cancer+normal vs

(cancer+normal vs

35297138 128750871 5 cancer+normal) cancer+normal)

(normal vs normal)

7- (cancer vs cancer) cgl3537061 cg0222786

(cancer+normal vs 8-22457446

35298720 (cancer+normal vs

7

cancer+normal) cancer+normal) (cancer vs cancer)

7- (cancer+normal vs 9- cgl415312

cgl4552801 (cancer+normal vs

65878734 cancer+normal) 131219302 6

cancer+normal)

(cancer vs cancer)

7- 9- cgl341462 (cancer+normal vs cgl4428815 (cancer+normal vs

65878911 132935646 9 cancer+normal) cancer+normal)

7- (cancer+normal vs 9- cg2122237 (cancer+normal vs cg26579491

65878976 cancer+normal) 136023905 0 cancer+normal)

Status - Hypo Status - Hypo

(normal vs normal) (cancer vs cancer)

1- cgl288811

cgl6553083 (cancer+normal vs 1-11107048 (cancer+normal vs

224698080 3

cancer+normal) cancer+normal)

(cancer vs cancer)

1- cg0450821 (cancer+normal vs cgl6908552 (cancer+normal vs 1-11107452

231174153 6 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

1- 1- cg0563011

cgl l811391 (cancer+normal vs (cancer+normal vs

23520083 150948030 1

cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 1- cg2446133

cg24633745 (cancer+normal vs

246930955 cancer+normal) 167882440 7

cancer+normal)

(normal vs normal)

(cancer vs cancer)

1- (cancer vs cancer) 1- cg2685966

cgl3187885 (cancer+normal vs

246930969 (cancer+normal vs 167883298 6

cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 1- cg2577816

cg27573570 (cancer+normal vs

28422839 cancer+normal) 171059935 6

cancer+normal)

(normal vs normal)

1- (cancer+normal vs 1- cgl806314 (cancer vs cancer) cg20687616

56883736 cancer+normal) 171060071 9 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cgl733065

1-8384659 cgl0508347 (cancer+normal vs (cancer+normal vs

173886454 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 1- cgl759157

cgl8396714 (cancer+normal vs (cancer+normal vs

95289024 179059407 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 1- cg2233227

cg23033014 (cancer+normal vs (cancer+normal vs

43849970 207277018 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 1- cgl 115396

cgO 1275661 (cancer+normal vs (cancer+normal vs

5504438 207277031 9

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- (cancer vs cancer) 1- cg2364637

cg20459238 (cancer+normal vs

88719950 (cancer+normal vs 209847618 5

cancer+normal) cancer+normal)

(normal vs normal)

10- (cancer vs cancer) 1- cg2688052 (cancer+normal vs cg07092097

88720025 (cancer+normal vs 209877941 5 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 1- cg0491883

cg08547848 (cancer+normal vs (cancer+normal vs

102339610 241795170 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cg2193267

cgl7256234 (cancer+normal vs 1-95584445 (cancer+normal vs

111311280 2

cancer+normal) cancer+normal)

11- (cancer+normal vs 10- cgO 172741 (cancer+normal vs cgl5215830

125999805 cancer+normal) 105616523 9 cancer+normal)

11- cg06679296 (cancer+normal vs 10-8546509 cgl 187504 (normal vs normal) 1949032 cancer+normal) 4 (cancer vs cancer)

(cancer+normal vs cancer+normal)

11- (cancer+normal vs 10- cgl835424 (cancer+normal vs cg06503573

1949039 cancer+normal) 93390311 8 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 10- cg2428852

cgl4849140 (cancer+normal vs (cancer+normal vs

4010752 93390347 7

cancer+normal) cancer+normal)

(normal vs normal)

11- (cancer vs cancer) 10- cgl403765 (cancer+normal vs cg03614381

71229642 (cancer+normal vs 93390387 2 cancer+normal) cancer+normal)

(normal vs normal)

11- 11- cgl848259 (cancer+normal vs cg04665565 (cancer+normal vs

71230734 126147781 3 cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer+normal vs 11- cg0037119

cg04939326 (cancer+normal vs

73278053 cancer+normal) 46740481 5

cancer+normal)

(cancer vs cancer)

12- (cancer+normal vs 11- cg2645336

cg21432513 (cancer+normal vs

133435770 cancer+normal) 46741373 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- (cancer vs cancer) 11- cg0900469

cgl8436898 (cancer+normal vs

47471907 (cancer+normal vs 46741405 1

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

12- cgl416459

cgl9198386 (cancer+normal vs 11-6462110 (cancer+normal vs

89811742 6

cancer+normal) cancer+normal)

(cancer vs cancer)

12- cgl727212 (cancer+normal vs cg00015699 (cancer+normal vs 11-6462828

90313589 6 cancer+normal) cancer+normal)

(cancer vs cancer)

12- 11- cgl925274 (cancer+normal vs cg20490773 (cancer+normal vs

90313611 68456607 1 cancer+normal) cancer+normal)

13- (cancer+normal vs 12- cgl695699 (cancer+normal vs cg06069407

114187548 cancer+normal) 133249241 9 cancer+normal)

(cancer vs cancer)

13- 12- cg0515990 (cancer+normal vs cg22612590 (cancer+normal vs

114187973 56515094 9 cancer+normal) cancer+normal)

(cancer vs cancer)

13- 12- cg0339997 (cancer+normal vs cgl3241681 (cancer+normal vs

114187990 57828847 1 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

13- 12- cgl063549 (cancer vs cancer) cg20539175 (cancer+normal vs

114188051 69199037 4 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

(cancer vs cancer)

15- 15- cgl797278 (cancer+normal vs cg22423363 (cancer vs cancer)

65042722 70372105 9 cancer+normal)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

15- (cancer+normal vs 16- cg0887925

cg06049171 (cancer+normal vs

69126265 cancer+normal) 20709238 5

cancer+normal)

(normal vs normal)

16- (cancer vs cancer) cg0519410 (cancer+normal vs cg27316811 16-2088960

1576146 (cancer+normal vs 2 cancer+normal) cancer+normal)

16- (cancer+normal vs cg0660496 (cancer+normal vs cg07019252 16-2522266

1576773 cancer+normal) 8 cancer+normal)

16- cg27587310 (cancer vs cancer) 16- cg0630229 (cancer+normal vs 29204994 (cancer+normal vs 58764886 5 cancer+normal) cancer+normal)

(cancer vs cancer)

17- 16- cgO 180074 (cancer+normal vs cg07564598 (cancer+normal vs

25619946 83981557 4 cancer+normal) cancer+normal)

17- (cancer+normal vs 16- cg0614386 (cancer+normal vs cg04970158

43208740 cancer+normal) 83981678 4 cancer+normal)

(cancer vs cancer)

17- 16- cgl 166711 (cancer+normal vs cg25504605 (cancer+normal vs

56569119 87969962 7 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- (cancer vs cancer) 16- cg0564099

cg02746913 (cancer+normal vs

75237550 (cancer+normal vs 87970367 2

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

16- cg0355086

17-767301 cgl3476078 (cancer vs cancer) (cancer+normal vs

87970376 4

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) 17- cg0209401 (cancer+normal vs

17-767334 cg25236028

(cancer+normal vs 17485934 8 cancer+normal) cancer+normal)

(cancer vs cancer)

17- cg2661989 (cancer+normal vs

17-767380 cgl3120258 (cancer+normal vs

19249164 4 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 17- cgl853612

cg07724971 (cancer+normal vs (cancer+normal vs

78035629 26694939 3

cancer+normal) cancer+normal)

(cancer vs cancer)

18- (cancer+normal vs 17- cgl660873

cgl3431373 (cancer+normal vs

5956002 cancer+normal) 27370988 1

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- (cancer vs cancer) cgl896495

cgl9338222 17-7019284 (cancer+normal vs

39052032 (cancer+normal vs 4

cancer+normal) cancer+normal)

(cancer vs cancer)

19- 17- cg0690123 (cancer+normal vs cgl9786121 (cancer+normal vs

39084308 77706717 8 cancer+normal) cancer+normal)

(cancer vs cancer)

19- 19- cg2749992 (cancer+normal vs cgl8668041 (cancer+normal vs

41190396 11351027 5 cancer+normal) cancer+normal)

(cancer vs cancer)

19- cg2580637 (cancer+normal vs cgl 1745755 (cancer+normal vs 19-2790585

8670086 0 cancer+normal) cancer+normal)

(cancer vs cancer)

2- cgl373392 (cancer+normal vs cgl6200531 (cancer+normal vs 19-4537901

135532566 3 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- (cancer vs cancer) 19- cg2743618

cg23212579 (cancer+normal vs

219256018 (cancer+normal vs 45449006 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- 2- cg2304141

cgl6926316 (cancer+normal vs (cancer+normal vs

219256101 113884447 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cg2611245

cgl0397934 (cancer+normal vs 2-21267334 (cancer+normal vs

242868376 7

cancer+normal) cancer+normal)

(cancer vs cancer)

2- 2- cg2392740 (cancer+normal vs cg20422417 (cancer+normal vs

25427108 234580842 5 cancer+normal) cancer+normal) (cancer vs cancer)

2- (cancer+normal vs 2- cg0443764

cg08369014

25809988 (cancer+normal vs cancer+normal) 234627450 8

cancer+normal)

2- (cancer+normal vs cg0118661

cg21708738 (cancer+normal vs

2-44065003

42175351 cancer+normal) 3 cancer+normal)

(normal vs normal)

2- (cancer vs cancer) cg2092672

cg08570458 (cancer+normal vs 2-44065725

45497191 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer)

(cancer vs cancer) cgl912333

cgl 1672772 2-44066294 (cancer+normal vs

75078286 (cancer+normal vs 9

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cg0076027

cg24560809 (cancer+normal vs 2-44067042

95939339 (cancer+normal vs

2

cancer+normal) cancer+normal)

(cancer vs cancer)

20- (cancer vs cancer)

21- cgl531016

cgl6208206 (cancer+normal vs

31446363 (cancer+normal vs

37852822 2

cancer+normal) cancer+normal)

(cancer vs cancer)

20- 21- cg2380870

cg04772817 (cancer+normal vs

(cancer+normal vs

32316843 37853496 4

cancer+normal) cancer+normal)

(cancer vs cancer)

20- 21- cgl686544 (cancer+normal vs cg24332577 (cancer+normal vs

50419248 37853516 2 cancer+normal) cancer+normal)

(cancer vs cancer)

20- 21- cg2298940 (cancer+normal vs cgl2288473 (cancer+normal vs

50419274 44590650 7 cancer+normal) cancer+normal)

(cancer vs cancer)

20- (cancer vs cancer)

21- cg0441314

cg25169524 (cancer+normal vs

56076737 (cancer+normal vs

47575134 7

cancer+normal) cancer+normal)

(cancer vs cancer)

20- (cancer vs cancer)

22- cg0963446

cgl 1853697 (cancer+normal vs

60510235 (cancer+normal vs

21128411 9

cancer+normal) cancer+normal)

21- (cancer vs cancer)

(cancer+normal vs 22- cg0403358

cg22117968 (cancer+normal vs

46768124 cancer+normal) 24891666 0

cancer+normal)

(cancer vs cancer)

21- (cancer vs cancer)

22- cgl865948

cgl3180920

46896174 (cancer+normal vs (cancer+normal vs

41630982 3

cancer+normal) cancer+normal)

(cancer vs cancer)

3- 22- cgl020108

cgl6827534 (cancer+normal vs

(cancer+normal vs

12332780 50644361 4 cancer+normal) cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer)

22- cg0736655

cg03513893 (cancer+normal vs

184052502 (cancer+normal vs

50644468 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer) 22- cg2187486

cgl0985281 (cancer+normal vs

194573301 (cancer+normal vs 50644682 2

cancer+normal) cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer)

22- cg2593470

cg07206256 (cancer+normal vs (cancer+normal vs

194573323 50644755 0

cancer+normal) cancer+normal)

(normal vs normal)

4- (cancer vs cancer)

3- cg2630168

cg03609493

11370314 (cancer+normal vs

142681704 (cancer+normal vs

9

cancer+normal) cancer+normal)

4- (cancer+normal vs 3- cgl 112279

cg09646593 (cancer+normal vs

125631168 cancer+normal) 194071770 5 cancer+normal)

(cancer vs cancer)

4- cg0814848

cg06775361 (cancer+normal vs

(cancer+normal vs 3-52812973

141188341 8 cancer+normal) cancer+normal)

4-3480656 cgl3455623 (cancer vs cancer) 3-52828594 cg2586555 (cancer+normal vs (cancer+normal vs 3 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer+normal vs cg2138018

4-7203326 cgl8011273 4-1198278 (cancer+normal vs cancer+normal) 1

cancer+normal)

(cancer+normal vs 4- cg0882397 (cancer+normal vs

4-802844 cg02689072

cancer+normal) 185724646 5 cancer+normal)

(cancer vs cancer)

5- 4- cgl935873 (cancer+normal vs cgl8114890 (cancer+normal vs

180219707 186734530 8 cancer+normal) cancer+normal)

(cancer vs cancer)

4- cg0419545 (cancer+normal vs

5-9557609 cg23920603 (cancer+normal vs

186734622 4 cancer+normal) cancer+normal)

(cancer vs cancer)

6- 4- cg2507417 (cancer+normal vs cgl7356964 (cancer+normal vs

106582638 187088169 0 cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 4- _C gl447778 (cancer+normal vs cg25581448

106582669 (cancer+normal vs 187088191 0 cancer+normal) cancer+normal)

6- (cancer+normal vs 5- cg2680202 (cancer+normal vs cg01692809

142959262 cancer+normal) 127872329 6 cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 5- cgl961680

cg03813151 (cancer+normal vs

149778058 cancer+normal) 139939823 7

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- (cancer vs cancer) 5- cg0418286

cg03329755 (cancer+normal vs

167189272 (cancer+normal vs 141346431 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 5- cg0120491

cg23221431 (cancer+normal vs (cancer+normal vs

18368796 142187317 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 5- cg0662576

cgl4645856 (cancer+normal vs (cancer+normal vs

18368844 176836695 7

cancer+normal) cancer+normal)

(cancer vs cancer)

6- 6- cg2117885 (cancer+normal vs cg23562023 (cancer+normal vs

24429162 160500620 1 cancer+normal) cancer+normal)

(normal vs normal)

6- 6- cg0239679 (cancer+normal vs cg26097381 (cancer+normal vs

31779598 160500689 7 cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cgl769301 (cancer+normal vs cg21552001 6-30001557

47202394 (cancer+normal vs 3 cancer+normal) cancer+normal)

(cancer vs cancer)

7- (cancer+normal vs cg0378112

cg02486364 6-30168380 (cancer+normal vs

13155344 cancer+normal) 3

cancer+normal)

7- (cancer+normal vs cgl 199090 (cancer+normal vs cg08202754 6-44196412

152621979 cancer+normal) 2 cancer+normal)

(cancer vs cancer)

7- cgl624335 (cancer+normal vs cg23730037 (cancer+normal vs 6-7142578

158596552 9 cancer+normal) cancer+normal)

(cancer vs cancer)

cg0986630 (cancer+normal vs

7-170692 cgl9210140 (cancer+normal vs 6-7142638

3 cancer+normal) cancer+normal)

7- (cancer+normal vs cg0135178 (cancer+normal vs cg07156115 6-7220085

17379753 cancer+normal) 3 cancer+normal)

(cancer+normal vs 7- cgl934662 (cancer+normal vs

7-190423 cgl7427491

cancer+normal) 101901663 3 cancer+normal)

7-1932321 cg23618217 (cancer vs cancer) 7-1197113 cg0392353 (cancer vs cancer) (cancer+normal vs 5 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) cgl555699

7-1961869 cgl5997393 (cancer+normal vs 7-80544479 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer) cg2515137

7-210075 cgl2458039 7-895646 (cancer+normal vs

(cancer+normal vs 6

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

8- cg0419303

cg01886570 (cancer vs cancer) 7-99637061 (cancer+normal vs

123966105 7

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

8- (cancer+normal vs 8- cg0097136

cg05516773 (cancer+normal vs

37643811 cancer+normal) 142263802 9

cancer+normal)

(normal vs normal) (normal vs normal)

Status - Hyper Status - Hyper

(normal vs normal)

1- 1- cg0940857

cg04933208 (cancer+normal vs (normal vs normal)

29586414 101003634 1

cancer+normal)

1- (cancer vs cancer) cgl 134462

cg21929771 1-14026360 (normal vs normal)

29586580 (normal vs normal) 6

(cancer vs cancer)

1- 1- cgl795266 (normal vs normal) cgl5158106 (normal vs normal)

39873077 145395753 1 (cancer+normal vs cancer+normal)

1- cg0870387

1-9602701 cg26607031 (normal vs normal) (normal vs normal)

151812421 2

10- 1- cg2442583

cg05749728 (normal vs normal) (normal vs normal)

126826902 151812435 8

10- 1- cg2436887

cgl0069493 (normal vs normal) (normal vs normal)

45914688 170899285 6

11- 1- cgl226939

cgl0616216 (normal vs normal) (normal vs normal)

128321662 205011999 4

11- 1- cgl385248

cgl0334741 (normal vs normal) (normal vs normal)

128321749 205195627 6

11- 1- cgl246740

cgl4801518 (normal vs normal) (normal vs normal)

128559075 207496045 4

12- 1- cgl735580

cg08900101 (normal vs normal) (normal vs normal)

114833043 231475345 9

12- cg2416257

cg25399352 (normal vs normal) 1-27817404 (normal vs normal)

114837572 9

(normal vs normal)

12- cg0887845

cg23820885 (cancer+normal vs 1-36915864 (normal vs normal)

114840942 0

cancer+normal)

12- 10- cgl566784

cgl l841394 (normal vs normal) (normal vs normal)

114841536 112256729 4

12- 10- cgl504457

cg00642359 (normal vs normal) (normal vs normal)

114841708 126434204 3

(normal vs normal)

12- cg2273724

cgl2437821 (cancer+normal vs 10-557605 (normal vs normal)

114852027 1

cancer+normal)

12- 10- cgl672200

cg20249252 (normal vs normal) (normal vs normal)

114852308 75771490 1

12- 10- cg0401298

cg06912966 (normal vs normal) (normal vs normal)

114852359 93350190 6

12- 11- cgl569471

cgl7970299 (normal vs normal) (normal vs normal)

54772804 118402280 5

12- cg00781208 (normal vs normal) 11- cg2691693 (normal vs normal) 64433590 121970613 6

13- 11- cgl529887

cg24526103 (normal vs normal) (normal vs normal)

110433784 124824789 5

13- 11- cg2557878

cg01569664 (normal vs normal) (normal vs normal) 110434016 128446070 1

16- 11- cgl932073

cg26624628 (normal vs normal) (normal vs normal)

67457663 27061756 0

16- 11- cgl714782

cg09941601 (normal vs normal) (normal vs normal)

86606899 61322255 0

(cancer vs cancer)

(cancer vs cancer)

17- 11- cgl884093

cgl9872299 (normal vs normal) (normal vs normal) 17686141 68350410 1

(cancer+normal vs

cancer+normal)

17- cg2413489

cgl3769834 (normal vs normal) 11-859670 (normal vs normal)

46713962 7

17- 12- cg2052546

cgl2698628 (normal vs normal) (normal vs normal)

46802740 12867724 1

17- cgl924472

cg09000583 (normal vs normal) 12-2048973 (normal vs normal)

46802888 2

17- cgl023167

cg08594218 (normal vs normal) 12-2944493 (normal vs normal)

46803008 5

17- cgl016220

cg21865150 (normal vs normal) 12-7038866 (normal vs normal)

46804239 9

17- (cancer vs cancer) cgl781593

cgl6779463 12-8191646 (normal vs normal)

75369055 (normal vs normal) 3

17- (cancer vs cancer) 12- cg0892230

cgl7300544 (normal vs normal)

75369091 (normal vs normal) 95226993 8

17- (cancer vs cancer) 14- cgl898410

cg03804136 (normal vs normal)

75369219 (normal vs normal) 104163025 3

17- 14- cg0188507

cgl5044248 (normal vs normal) (normal vs normal)

75369224 90168304 1

17- 14- cgl890189

cg02884239 (normal vs normal) (normal vs normal)

75369228 90168351 5

17- cg2691305

cg20275528 (normal vs normal) 16-419975 (normal vs normal)

75369484 8

(cancer vs cancer)

(cancer vs cancer)

17- cg0002153

cgl4517217 (normal vs normal) 16-4324280 (normal vs normal)

75447478 2

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- 16- cg2707311

cgl8104645 (normal vs normal) (normal vs normal)

75447504 56228744 3

(cancer+normal vs

cancer+normal)

19- 16- cg2716219

cg03965138 (normal vs normal) (normal vs normal)

52134393 75183231 6

2- 16- cg0827736

cgl5707428 (normal vs normal) (normal vs normal)

11679845 84538885 9

2- 16- cg0925908

cgl3808071 (normal vs normal) (normal vs normal)

11679872 84538889 1

2- 17- cgl l51200

cgl4653284 (normal vs normal) (normal vs normal)

11679879 38220694 9

2- 17- cgl 104907

cgl7208060 (normal vs normal) (normal vs normal)

11680086 42199063 5

2- 17- cgl717876

cg24914355 (normal vs normal) (normal vs normal)

176959229 55682851 1

2- 17- cg0390984

cgl7495130 (normal vs normal) (normal vs normal)

176960255 79477206 9

2- cg20605061 (normal vs normal) 17- cg0435230 (normal vs normal) 176973835 80654922 5

2- cgl557029

cgl 1272491 (normal vs normal) 19-2327692 (normal vs normal)

176974934 3

2- 19- cg0439699

cg00095728 (normal vs normal) (normal vs normal)

176976081 49376722 8

2- 19- cg2330556

cgl8064824 (normal vs normal) (normal vs normal)

176978893 54369576 7

2- cgl208557

cgl3911052 (normal vs normal) 19-8674501 (normal vs normal)

176978909 0

2- 2- cgl l l2413

cg00679731 (normal vs normal) (normal vs normal)

176979345 119067579 0

20- (cancer vs cancer) 2- cgl596519

cgl3544006 (normal vs normal) 34189411 (normal vs normal) 208370032 0

3- 2- cg0529389

cgl5038286 (normal vs normal) (normal vs normal)

128200723 226913713 7

3- cgl458367

cg07038342 (normal vs normal) 2-44058776 (normal vs normal)

145969625 5

3- cgl976908

cg03876340 (normal vs normal) 2-44460827 (normal vs normal)

155570582 0

(normal vs normal)

4- cg2025471

cg06374962 (cancer+normal vs 20-1371017 (normal vs normal)

111531926 8

cancer+normal)

(normal vs normal)

4- 20- cgl 186449

cgl8064927 (cancer+normal vs (normal vs normal)

111531975 33759605 0

cancer+normal)

(normal vs normal)

4- 20- cgl611697

cg22006640 (cancer+normal vs (normal vs normal)

111532035 33759608 3

cancer+normal)

(normal vs normal)

4- 21- cg2504658

cgl 1416290 (cancer+normal vs (normal vs normal)

111532410 32932016 4

cancer+normal)

4- 21- cg2703701

cg23404248 (normal vs normal) (normal vs normal)

111533195 35320667 3

4- 22- cg2619653

cgl2652641 (normal vs normal) (normal vs normal)

111533267 36236656 1

4- 22- cgl861332

cg02719154 (normal vs normal) (normal vs normal)

111533823 36236760 4

4- 3- cg2353871

cgl 1930400 (normal vs normal) (normal vs normal)

111533883 143567031 8

4- cgl349604

cg04355159 (normal vs normal) 3-14494726 (normal vs normal)

111533951 1

4- 3- cg2300322

cgl3292042 (normal vs normal) (normal vs normal)

111535334 193922630 5

4- cgl348791

cg23806894 (normal vs normal) 3-38067350 (normal vs normal)

111535528 8

4- cg2635329

cg09780241 (normal vs normal) 3-49378124 (normal vs normal)

111535597 6

4- cg2088626

cgl9849728 (normal vs normal) 3-53196104 (normal vs normal)

111536767 3

4- cgl900798

cg23646776 (normal vs normal) 3-87277465 (normal vs normal)

111536970 8

4- 4- cg2686913

cg01951086 (normal vs normal) (normal vs normal)

111551642 116035082 1

4- 4- cg0073088

cg02725370 (normal vs normal) (normal vs normal)

111551829 160149604 7

4- 4- cg0681461 (cancer vs cancer) cg03943773 (normal vs normal)

111552308 173961344 6 (normal vs normal)

5- cgl010672

cg23024136 (normal vs normal) 4-3071494 (normal vs normal)

153853154 5

5- cgl221436

cgl7009842 (normal vs normal) 4-80977132 (normal vs normal)

153854401 6 5- cgl653639

cg23178714 (normal vs normal) 4-84205065 (normal vs normal)

153855031 0

(cancer vs cancer)

6- (normal vs normal) cgl068535

cg23413349 4-87814065 (normal vs normal)

106958388 (cancer+normal vs 9

cancer+normal)

5- cg2521847

6-1384591 cgl4258623 (normal vs normal) (normal vs normal)

125759767 0

5- cgl809033

6-1384705 cgl6424078 (normal vs normal) (normal vs normal)

132111426 1

cgl019602

6-1384780 cg09651522 (normal vs normal) 5-35003575 (normal vs normal)

6

cg0360401

6-1395278 cgl6935061 (normal vs normal) 5-400201 (normal vs normal)

1

6- cg2470888

cg05945401 (normal vs normal) 5-90369235 (normal vs normal)

31506990 2

7- cg0503323

cg04132407 (normal vs normal) 5-90458832 (normal vs normal)

130626376 9

7- 6- cgl454772

cg09662496 (normal vs normal) (normal vs normal)

130626474 116832794 6

7- 6- cg2545480

cg26297005 (normal vs normal) (normal vs normal)

27162090 126660984 4

7- cgl567654

cgl 1117878 (normal vs normal) 6-26421231 (normal vs normal)

35294949 2

7- cgl 111261

cgl8011916 (normal vs normal) 6-2970624 (normal vs normal)

35295120 5

7- cg2011767

cg22056346 (normal vs normal) 6-30641220 (normal vs normal)

35296040 5

7- cg0591390

cgl 1838668 (normal vs normal) 6-30923370 (normal vs normal)

35296189 6

7- cg2177658

cgl5311814 (normal vs normal) 6-30923545 (normal vs normal)

35296213 3

7- cgl804916

cg01688536 (normal vs normal) 6-32121261 (normal vs normal)

35296968 7

(normal vs normal)

7- cg0971213

cg22051964 (cancer+normal vs 6-40995388 (normal vs normal)

35297138 5

cancer+normal)

7- cgl894132

cg22584618 (normal vs normal) 6-6700205 (normal vs normal)

35298212 2

7- cg2430275

cg08732352 (normal vs normal) 6-80853625 (normal vs normal)

35298391 2

(normal vs normal)

7- 7- cgl560389

cgl3537061 (cancer+normal vs (normal vs normal)

35298720 100231672 6

cancer+normal)

7- 7- cg0944998

cg05809668 (normal vs normal) (normal vs normal)

35301188 151328116 8

7- cg2712054

cg20061010 (normal vs normal) 7-15555129 (normal vs normal)

35301861 3

7- cg0916023

cgl5649852 (normal vs normal) 7-1765313 (normal vs normal)

65879115 1

8- cg0710742

cgl3949137 (normal vs normal) 7-8010894 (normal vs normal)

27560492 0

8- 8- cg2619252

cgl 1878331 (normal vs normal) (normal vs normal)

72469507 101960390 0

9- 8- cgl013833

cgl3663116 (normal vs normal) (normal vs normal)

116372034 142289648 8

9- 9- cg2119576

cgOOl 16234 (normal vs normal) (normal vs normal)

18474243 133700022 3

Status - Hypo Status - Hypo

1- cgl672480

1-1118157 cgl6366262 (normal vs normal) (normal vs normal)

121259813 0 1- cg0297344

1-1396296 cg20951194 (normal vs normal) (normal vs normal)

145366536 1

1- 1- cgl319917

cg09797837 (normal vs normal) (normal vs normal)

17734771 145375603 8

(normal vs normal)

1- 1- cg0563011

cg27542729 (normal vs normal) (cancer+normal vs

177850564 150948030 1

cancer+normal)

(normal vs normal)

1- 1- cg0878600

cgl6553083 (cancer+normal vs (normal vs normal)

224698080 157670710 3

cancer+normal)

(normal vs normal)

1- (cancer vs cancer) 1- cg0847460

cgl3187885 (normal vs normal)

246930969 (cancer+normal vs 159684431 3

cancer+normal)

1- cg0142985

cg27168493 (normal vs normal) 1-16163775 (normal vs normal)

67636724 9

1- cg0443955

cg09515098 (normal vs normal) 1-1689452 (normal vs normal)

92942075 7

(normal vs normal)

10- 1- cgl806314 (cancer vs cancer) cgl6734433 (normal vs normal)

115860297 171060071 9 (cancer+normal vs

cancer+normal)

10- 1- cgl009056

cg04636331 (normal vs normal) (normal vs normal)

1509224 217241497 8

10- cg0091422

cg20327845 (normal vs normal) 1-29585898 (normal vs normal)

3138418 2

10- cg2396073

cgl7983571 (normal vs normal) 1-4171594 (normal vs normal)

65186953 6

cgl008962

10-682841 cg25020678 (normal vs normal) 1-45969600 (normal vs normal)

6

(normal vs normal)

10- (cancer vs cancer) cg0607000

cg07092097 1-45986120 (normal vs normal)

88720025 (cancer+normal vs 2

cancer+normal)

11- 10- cg0321082

cg00379713 (normal vs normal) (normal vs normal)

124940631 104574906 7

11- 10- cg0567307

cg05898618 (normal vs normal) (normal vs normal)

2555576 110084660 9

11- 10- cgl527264

cgl3179056 (normal vs normal) (normal vs normal)

50220389 121775065 1

(normal vs normal)

11- (cancer vs cancer) 10- cgl425004

cg03614381 (normal vs normal)

71229642 (cancer+normal vs 135340785 8

cancer+normal)

(normal vs normal)

11- cg2639419

cg04665565 (cancer+normal vs 10-1453818 (normal vs normal)

71230734 6

cancer+normal)

11- 10- cgl352569

cg03274739 (normal vs normal) (normal vs normal)

98437942 61320994 7

12- 10- cgl 193027

cg26112390 (normal vs normal) (normal vs normal)

100550390 74879093 4

(normal vs normal)

12- cgl 187504 (cancer vs cancer) cg26277026 (normal vs normal) 10-8546509

22486029 4 (cancer+normal vs

cancer+normal)

12- 10- cg0682107

cg23378074 (normal vs normal) (normal vs normal)

30947871 99933209 5

12- 11- cgl004963

cg27272293 (normal vs normal) (normal vs normal)

76531007 112162100 1

12- (normal vs normal) cg2238644

cgl9198386 11-1704632 (normal vs normal)

89811742 (cancer+normal vs 2 cancer+normal)

13- 11- cgl702283

cgl8363035 (normal vs normal) (normal vs normal)

20805385 65203222 0

13- 11- cg0547364

cg03473518 (normal vs normal) (normal vs normal)

20805656 79113178 8

13- 12- cg2087404

cg22377389 (normal vs normal) (normal vs normal)

20805679 102874832 4

13- 12- cgl787827

cg07165066 (normal vs normal) (normal vs normal)

23952576 45266836 3

(normal vs normal)

13- 12- cgl063549 (cancer vs cancer) cgl8865990 (normal vs normal)

45970273 69199037 4 (cancer+normal vs

cancer+normal)

13- 13- cgO 129702

cgl7300047 (normal vs normal) (normal vs normal)

49108353 106117425 0

14- 13- cgl853541

cg07921759 (normal vs normal) (normal vs normal)

55203969 113793268 0

(normal vs normal)

14- 14- cgl840336

cg04791162 (cancer+normal vs (normal vs normal)

62331287 38725750 1

cancer+normal)

15- 15- cg0233068

cgl8471471 (normal vs normal) (normal vs normal)

100537686 41787940 3

15- 15- cg0518573

cg04200704 (normal vs normal) (normal vs normal)

25486871 70371992 8

15- 16- cgl913346

cgl0548669 (normal vs normal) (normal vs normal)

37782940 12355834 6

15- 16- cg2728103

cg03050022 (normal vs normal) (normal vs normal)

55559759 30348681 6

(normal vs normal)

(cancer vs cancer)

15- 16- cgl341610

cg22423363 (cancer vs cancer) (normal vs normal)

65042722 33259538 9

(cancer+normal vs

cancer+normal)

(normal vs normal)

16- (cancer vs cancer) 16- cg0499905

cg27316811 (normal vs normal)

1576146 (cancer+normal vs 73644907 8

cancer+normal)

16- 17- cgl533295

cg08524717 (normal vs normal) (normal vs normal)

29152077 21194739 1

16- cg0074724

cg08585897 (normal vs normal) 17-3377265 (normal vs normal)

75680535 1

17- 17- cgl709527

cg03499000 (normal vs normal) (normal vs normal)

16521057 64225346 9

17- 17- cg2656589

cg25657218 (normal vs normal) (normal vs normal)

22017062 73501109 3

17- 18- cgl687458

cgl 1792281 (normal vs normal) (normal vs normal)

26443366 55092509 0

18- cg0372565

17-292975 cg23015327 (normal vs normal) (normal vs normal)

76073399 2

17- 19- cgl209000

cg01218720 (normal vs normal) (normal vs normal)

40322138 17516282 3

(normal vs normal)

17- (cancer vs cancer) 19- cgl636358

cg01883155 (normal vs normal)

74565009 (cancer+normal vs 17516329 6

cancer+normal)

(normal vs normal)

17- (cancer vs cancer) 19- cg0999369

cg02746913 (normal vs normal)

75237550 (cancer+normal vs 17517008 9

cancer+normal)

(normal vs normal) 19- cg2009212

17-767301 cgl3476078 (normal vs normal)

(cancer vs cancer) 17517221 2 (cancer vs cancer)

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer) cgl936704

17-767334 cg25236028 19-5076681 (normal vs normal)

(cancer+normal vs 7

cancer+normal)

17- 2- cg0234711

cgl4073057 (normal vs normal) (normal vs normal)

78796363 101752032 3

17- 2- cg2515258

cg25105415 (normal vs normal) (normal vs normal)

79913327 121261361 4

17- 2- cgl647814

cg22325292 (normal vs normal) (normal vs normal)

80708367 188419830 5

19- 2- cg0360764

cgl7387694 (normal vs normal) (normal vs normal)

32833011 234668930 8

2- 2- cgl l81184

cgl4501281 (normal vs normal) (normal vs normal)

10360265 234669166 0

2- cgl222324

cgl3024117 (normal vs normal) 2-60643473 (normal vs normal)

139659766 3

2- cg2424062

cg23008083 (normal vs normal) 2-79386720 (normal vs normal)

161057625 6

2- cg0302722

cg22047295 (normal vs normal) 2-80221468 (normal vs normal)

175462522 7

2- 20- cg2187859

cgl9275653 (normal vs normal) (normal vs normal)

175532338 25583652 8

2- 20- cg0790822

cg25300318 (normal vs normal) (normal vs normal)

200527297 56225978 3

2- 20- cg0549297

cgl2930176 (normal vs normal) (normal vs normal)

232044866 60119508 5

(normal vs normal)

2- 20- cg0437904

cg08570458 (cancer+normal vs (normal vs normal)

45497191 62364801 1

cancer+normal)

2- 21- cg2670972

cg24267275 (normal vs normal) (normal vs normal)

88958370 41027960 0

21- 22- cg0733109

cg20516845 (normal vs normal) (normal vs normal)

43823604 50584184 8

22- 3- cg0726900

cgl 1141652 (normal vs normal) (normal vs normal) 24348549 142681516 3

22- 3- cgl572604

cgl 1549874 (normal vs normal) (normal vs normal) 31202478 145790097 5

3- 3- cgl236986

cg01562552 (normal vs normal) (normal vs normal)

127543493 184035508 9

3- 3- cgl739204

cg21502476 (normal vs normal) (normal vs normal)

152939561 188495102 3

3- 3- cg0390550

cgl2798564 (normal vs normal) (normal vs normal)

75263641 191887304 0

4- 3- cgl259480

cgl0820262 (normal vs normal) (normal vs normal)

111866929 196908930 3

(normal vs normal)

4- 4- cg0797302

cg03609493 (cancer+normal vs (normal vs normal)

11370314 103553119 6

cancer+normal)

4- 4- cg2033473

cg21843114 (normal vs normal) (normal vs normal)

26334859 151502939 8

4- 4- cg0067526

cg09614876 (normal vs normal) (normal vs normal)

52861831 187291940 0

4- cg0046981

4-6809109 cgl6506970 (normal vs normal) (normal vs normal)

188953677 4

5- cg0737602

cg26938014 (normal vs normal) 4-72650992 (normal vs normal)

122432628 9

5- cgl773382

cg27323430 (normal vs normal) 5-1099592 (normal vs normal)

126387527 4 cgl899798

5-1462820 cg04005843 (normal vs normal) 5-1109031 (normal vs normal)

3

5- 5- cgl263098

cg07245677 (normal vs normal) (normal vs normal)

156280628 127872200 3

cg2337785

5-2338998 cg26986989 (normal vs normal) 5-1339812 (normal vs normal)

2

5- 5- cg0253915

cg24585035 (normal vs normal) (normal vs normal)

32522852 140614765 3

5- cg2761948

cg23408558 (normal vs normal) 5-17595441 (normal vs normal)

56679194 9

6- cgl061576

cg02424007 (normal vs normal) 5-42991657 (normal vs normal)

110967726 5

6- 6- cg0843032

cg02769951 (normal vs normal) (normal vs normal)

130758149 100442489 5

6- cgl088097

6-1515524 cg09344041 (normal vs normal) (normal vs normal)

157982213 3

6- 6- cgl762285

cg08875433 (normal vs normal) (normal vs normal)

29604148 157982358 5

(normal vs normal)

6- 6- cg0951166

cg26097381 (cancer+normal vs (normal vs normal)

31779598 160500971 2

cancer+normal)

7- cgl812697 (normal vs normal) cg26613811 (normal vs normal) 6-29588988

150054588 8 (cancer vs cancer)

7- cg2164474

cg08037327 (normal vs normal) 6-29599248 (normal vs normal)

150211061 0

7- cg0424612

cgl8116285 (normal vs normal) 6-29893273 (normal vs normal)

155581411 3

7- cg0315758

cgl4584961 (normal vs normal) 6-32006079 (normal vs normal)

157533065 8

(normal vs normal)

7- (cancer vs cancer) cg2467634

cg07573366 6-41377288 (normal vs normal)

32802765 (cancer+normal vs 6

cancer+normal)

7- 7- cg2659306

cg03951180 (normal vs normal) (normal vs normal)

72742151 157446092 7

7- cg0455537

cg01381374 (normal vs normal) 7-1902093 (normal vs normal)

93474158 9

(normal vs normal)

(cancer vs cancer)

8- cg0503193

cg01886570 (cancer vs cancer) 7-214779 (normal vs normal)

123966105 1

(cancer+normal vs

cancer+normal)

8- cg2647859

cg06795722 (normal vs normal) 7-41747322 (normal vs normal)

143429730 9

8- cgl628216

cg03602212 (normal vs normal) 8-71159989 (normal vs normal)

25678826 0

8- cg0929725

cg26243740 (normal vs normal) 8-7631214 (normal vs normal)

42012513 2

cg0004511

8-793504 cg02840008 (normal vs normal) 8-93076177 (normal vs normal)

8

8- 9- cg0096927

cg25680105 (normal vs normal) (normal vs normal)

82434497 117093052 1

8- cgl425570

cg06895436 (normal vs normal) 9-95378254 (normal vs normal)

82434543 0

BRCA (cancer vs LUAD (cancer vs

cancer) cancer)

Status - Hyper Status - Hyper

(cancer vs cancer)

1- 1- cg0291891

cg22790257 (cancer+normal vs (cancer vs cancer)

151694108 151032962 0

cancer+normal)

1- cg06100368 (cancer vs cancer) 1- cgl032560 (cancer vs cancer) 151694123 (cancer+normal vs 220101785 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg0090742

cg05160181 (cancer vs cancer) 1-23668691 (normal vs normal)

151694281 7

(cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg0871809

cgl 1902458 (cancer vs cancer) 1-23668792 (normal vs normal)

154842746 7

(cancer+normal vs cancer+normal)

1- cg0812307 (cancer vs cancer) cg23414228 (cancer vs cancer) 1-28764523

155043413 4 (cancer vs cancer)

(cancer vs cancer)

1- cg0486597 (cancer vs cancer) cgl2664038 (cancer vs cancer) 1-40609565

156611194 6 (cancer+normal vs cancer+normal)

(cancer vs cancer)

1- 10- cgl015059

cgl 1199869 (cancer+normal vs (cancer vs cancer)

171220575 102440856 2

cancer+normal)

1- 10- cg2274829 (cancer vs cancer) cg07040244 (cancer vs cancer)

231555522 102489344 0 (cancer vs cancer)

10- cgl289444

1-2985218 cg08528984 (cancer vs cancer) (cancer vs cancer)

119304104 9

(cancer vs cancer) cg2278318 (cancer vs cancer)

1-2985312 cgl9356825 (cancer vs cancer) 10-8091753

0 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

cgl807262 (cancer vs cancer)

1-6508592 cgl5274864 (cancer+normal vs 10-8092036

9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

cgl580386 (cancer vs cancer)

1-6508954 cg25097074 (cancer+normal vs 10-8092165

9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

1- cgl671089 (cancer vs cancer) cgl2303627 (cancer vs cancer) 10-8092264

75549256 4 (cancer+normal vs cancer+normal)

(cancer vs cancer)

10- cg0572151 (cancer vs cancer) cgl9306063 (cancer vs cancer) 10-8095288

135171503 5 (cancer+normal vs cancer+normal)

(cancer vs cancer)

11- cg0972801 (cancer vs cancer) cgl8565473 (cancer+normal vs 10-8096305

128392102 2 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

11- cg2464727 (cancer vs cancer) cg04017555 (cancer+normal vs 10-8096311

61062704 6 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

11- (normal vs normal) cg0122489

cg27175288 10-8096368 (cancer vs cancer)

61062837 (cancer+normal vs 1

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- (normal vs normal) cgl518755 (cancer vs cancer) cg05190577 10-8096370

61062843 (cancer+normal vs 0 (cancer+normal vs cancer+normal) cancer+normal)

11- (cancer vs cancer) cg0247165 (cancer vs cancer) cg06282270 11-279950

61062910 (normal vs normal) 8 (cancer vs cancer) (cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

11- 11- cgl827062 (cancer vs cancer) cg25361844 (cancer vs cancer)

65405362 31831974 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- 11- cg2684808 (cancer vs cancer) cgl7480646 (cancer+normal vs

65405466 31832246 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- 11- cg0584003 (cancer vs cancer) cg01640437 (cancer+normal vs

65405484 31832353 1 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

11- 11- cgl036418 (cancer vs cancer) cg27068330 (cancer+normal vs

65405492 36615998 2 (cancer vs cancer) cancer+normal)

11- 11- cg2127299 (cancer vs cancer) cg01685242 (cancer vs cancer)

65405760 57529255 6 (cancer vs cancer)

(cancer vs cancer)

12- 11- cgl083121 (cancer vs cancer) cg20489228 (cancer+normal vs

115125549 57529419 2 (cancer vs cancer) cancer+normal)

12- 11- cgl921027 (cancer vs cancer) cg03396103 (cancer vs cancer)

116946354 57529465 6 (cancer vs cancer)

12- 11- cgl424580

cg05227549 (cancer vs cancer) (cancer vs cancer)

1770782 68081226 4

(cancer vs cancer)

12- 12- cg2412444

cg07731191 (cancer+normal vs (cancer vs cancer)

54329010 107711648 3

cancer+normal)

12- 12- cg2763031 (cancer vs cancer) cg04070651 (cancer vs cancer)

54611596 115120847 1 (cancer vs cancer)

12- 12- cgl971303 (cancer vs cancer) cg26503178 (cancer vs cancer)

58004731 115121016 8 (cancer vs cancer)

13- cg2352443

cgl6766325 (cancer vs cancer) 12-2161437 (cancer vs cancer)

80912906 6

(cancer vs cancer)

13- 15- cg2270688 (cancer vs cancer) cgl5247434 (cancer+normal vs

95201296 67814880 3 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

15- 16- cg0498108

cg05739476 (cancer+normal vs (cancer vs cancer)

72072813 15489614 8

cancer+normal)

15- 16- cg0736739

cg25385940 (cancer vs cancer) (cancer vs cancer)

99789637 55090870 5

(cancer vs cancer)

16- 16- cgl l l8117 (cancer vs cancer) cg07070305 (cancer vs cancer)

21831860 55090946 1 (cancer+normal vs cancer+normal)

(cancer vs cancer)

16- 16- cg0131777

cg09705457 (cancer+normal vs (cancer vs cancer)

46824143 55405200 2

cancer+normal)

(cancer vs cancer)

17- 16- cg0427608 (cancer vs cancer) cgl4527050 (cancer+normal vs

34077244 86478190 4 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

17- 16- cg0131390 (cancer vs cancer) cg09679923 (cancer vs cancer)

36103036 86609963 4 (cancer+normal vs cancer+normal)

17- 17- cgl 164179

cgl5802396 (cancer vs cancer) (cancer vs cancer)

7108305 38821429 1

17- (cancer vs cancer) 17- cgl505612

cg22764700 (cancer vs cancer)

75798605 (cancer+normal vs 38821487 8 cancer+normal)

19- 17- cg0619024

cg27067425 (cancer vs cancer) (cancer vs cancer)

15695299 48284395 4

19- 17- cg2112634

cg03730474 (cancer vs cancer) (cancer vs cancer)

15695817 70119120 4

19- 18- cg0706449 (cancer vs cancer) cgl9493303 (cancer vs cancer)

41414353 29304111 5 (cancer vs cancer)

(cancer vs cancer)

2- 18- cgl882020

cgl8261069 (cancer+normal vs (cancer vs cancer)

100175704 72124685 9

cancer+normal)

(cancer vs cancer)

2- 19- cg0619748 (cancer vs cancer) cg24797187 (cancer+normal vs

100175768 13107252 2 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

2- 19- cg2066577

cgl7165836 (cancer+normal vs (cancer vs cancer)

100175805 13134254 4

cancer+normal)

(cancer vs cancer)

2- cg0809114 (cancer vs cancer) cg01381586 (cancer+normal vs 19-1676011

10587627 7 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

2- 19- cgl 128293

cg09068528 (cancer vs cancer) (cancer+normal vs

211090171 17007648 6

cancer+normal)

(cancer vs cancer)

2- 19- cg2454883

cg05454076 (cancer vs cancer) (cancer+normal vs

219763330 17007698 3

cancer+normal)

(cancer vs cancer)

2- cgl552734

cgl8663033 (cancer+normal vs 19-1753636 (cancer vs cancer)

241034966 8

cancer+normal)

(cancer vs cancer)

20- (normal vs normal) 19- cgl476177

cg09923107 (cancer vs cancer)

30193892 (cancer+normal vs 31211050 3

cancer+normal)

(cancer vs cancer)

20- 19- cg2488457 (cancer vs cancer) cg00494337 (cancer+normal vs

30194024 58661833 2 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

20- 2- cg2161604 (cancer vs cancer) cgl6666964 (cancer+normal vs

37274692 224467359 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

20- 20- cgl332622

cg23884187 (cancer+normal vs (cancer vs cancer)

37275069 20349168 7

cancer+normal)

(cancer vs cancer)

21- cg0661607

cgl7648210 (cancer+normal vs 20-4130531 (cancer vs cancer)

46352817 7

cancer+normal)

22- 20- cgl204184

cg07194846 (cancer vs cancer) (cancer vs cancer)

19930177 45523294 8

(cancer vs cancer)

22- 20- cg2134391 (cancer vs cancer) cg02893180 (cancer vs cancer)

50919493 46413743 9 (cancer+normal vs cancer+normal)

3- 20- cg2208461 (cancer vs cancer) cg07185974 (cancer vs cancer)

18485529 46414934 1 (cancer vs cancer)

3- 21- cgl476920 (cancer vs cancer) cg24668089 (cancer vs cancer)

19189751 38071807 7 (cancer vs cancer)

(cancer vs cancer)

3- 21- cg2435860 (cancer vs cancer) cg02607683 (cancer+normal vs

72149807 40984553 3 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

3- 21- cg2026935 (cancer vs cancer) cgl9996971 (cancer+normal vs

72149921 40984610 9 (cancer vs cancer) cancer+normal) (cancer vs cancer)

(cancer vs cancer)

3- (normal vs normal) 21- cgl790085

cg03416562 (cancer+normal vs

85010677 (cancer+normal vs 40984777 4

cancer+normal) cancer+normal)

(cancer vs cancer)

4- 21- cg0844866 (cancer vs cancer) cg27064287 (cancer vs cancer)

102712082 40984780 5 (cancer+normal vs cancer+normal)

(cancer vs cancer)

4- 21- cg0370199

cg09690103 (cancer+normal vs (cancer vs cancer)

14603924 40984886 2

cancer+normal)

22- cg0913753

4-1811823 cg22548054 (cancer vs cancer) (cancer vs cancer)

46469091 3

(cancer vs cancer)

(cancer vs cancer)

5- 3- cg0005257 (cancer vs cancer) cgl9516279 (cancer+normal vs

151153922 132843565 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

5- cgl279149 (cancer vs cancer) cg27615363 (cancer+normal vs 4-57522094

174120078 2 (cancer vs cancer) cancer+normal)

5- 5- cg0005470 (cancer vs cancer) cg00041599 (cancer vs cancer)

176240038 135528543 2 (cancer vs cancer)

5- 5- cg2499648 (cancer vs cancer) cgl7269733 (cancer vs cancer)

43041146 174178256 2 (cancer vs cancer)

5- 5- cg2427186

cg08358683 (cancer vs cancer) (cancer vs cancer)

43602380 174178647 3

(cancer vs cancer)

5- cg2612159

6-1313730 cgl4732248 (cancer+normal vs (cancer vs cancer)

175298564 1

cancer+normal)

6- 5- cgl602509 (cancer vs cancer) cgl7364114 (cancer vs cancer)

160769359 175298655 4 (cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer)

6- 5- cgl356488 (cancer vs cancer) cg07237939 (cancer+normal vs

160769754 175298869 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(normal vs normal) cg0855429

6-3053739 cg02335642 5-59189934 (cancer vs cancer)

(cancer+normal vs 5

cancer+normal)

(cancer vs cancer)

6- 6- cg0062440

cg07979401 (cancer+normal vs (cancer vs cancer)

33739406 106442588 4

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 6- cg0641339 (cancer vs cancer) cgl8005901 (cancer+normal vs

33739558 110736865 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 6- cg0080407 (cancer vs cancer) cgl6010596 (cancer+normal vs

33739607 110736941 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

6- 6- cgl578589 (cancer vs cancer) cgl3859433 (cancer vs cancer)

33739653 144608500 8 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 6- cg0591773

cg23194609 (cancer vs cancer) (normal vs normal)

71122524 152623304 2

(cancer+normal vs cancer+normal)

7- (cancer vs cancer) 6- cg0268245 (cancer vs cancer) cg06962782

100091575 (cancer+normal vs 152623387 7 (cancer vs cancer) cancer+normal) (normal vs normal)

(cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 6- cgl202362

cg24881205 (cancer vs cancer) (normal vs normal)

20826188 152623479 5

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- 6- cg2330983 (cancer vs cancer) cg27135125 (cancer+normal vs

23510082 165341320 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

7- cg2340739

cg20265043 (cancer+normal vs 6-26197481 (cancer vs cancer)

23510089 6

cancer+normal)

(cancer vs cancer)

7- cg2713386 (cancer vs cancer) cg07297397 (cancer+normal vs 6-26216541

23510112 4 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

7- cg0385486 (cancer vs cancer) cg22826239 (cancer+normal vs 6-26224070

23510123 5 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

7- cgl607001 (cancer vs cancer) cgl6466899 (cancer+normal vs 6-26224392

23510693 8 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

7- cg2444094 (cancer vs cancer) cg27322103 (cancer vs cancer) 6-26224668

23513335 1 (cancer+normal vs cancer+normal)

7- cgl592907

cgl 1849717 (cancer vs cancer) 6-33267996 (cancer vs cancer)

55088104 8

8- cgl748969 (cancer vs cancer) cg03533519 (cancer vs cancer) 6-50680997

24857567 5 (cancer vs cancer)

8- 7- cg2510943

cgl2845520 (cancer vs cancer) (cancer vs cancer)

99076734 130419057 1

(cancer vs cancer)

(cancer vs cancer)

9- (normal vs normal) 7- cg0565196

cg01027151 (cancer+normal vs

129372349 (cancer+normal vs 130419064 0

cancer+normal) cancer+normal)

(cancer vs cancer)

9- 7- cgl875168

cgl4082645 (cancer+normal vs (cancer vs cancer)

129372478 130419066 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- (normal vs normal) cg0369458 (cancer vs cancer) cgl9337180 7-2271722

129373499 (cancer+normal vs 0 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

9- cgl696788

cgl4642696 (cancer+normal vs 7-27213971 (cancer vs cancer)

129386671 0

cancer+normal)

(cancer vs cancer)

9- (normal vs normal) cg0674574

cgl2777520 7-81399587 (cancer vs cancer)

129387303 (cancer+normal vs 0

cancer+normal)

(cancer vs cancer)

9- cg2604543 (cancer vs cancer) cgl5689835 (cancer+normal vs 8-21987861

129387721 4 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

9- cg2670292 (cancer vs cancer) cgl3979277 (cancer+normal vs 8-21988147

129388281 9 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

9- cg2245975

cg04693928 (cancer+normal vs 8-49293005 (cancer vs cancer)

129388668 5

cancer+normal) (cancer vs cancer)

9- cgl456087 (cancer vs cancer) cgl4409032 (cancer vs cancer) 9-81871926

129445219 2 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

9- cgl384856 (cancer vs cancer) cgl4100888 (cancer+normal vs 9-89561175

129445599 6 (cancer vs cancer) cancer+normal)

Status - Hypo Status - Hypo

(cancer vs cancer)

(cancer vs cancer)

1- 1- cg2405836 (cancer vs cancer) cg09896211 (cancer+normal vs

108232421 110923328 5 (cancer+normal vs

cancer+normal)

cancer+normal)

1- 1- cgl264350 (cancer vs cancer) cg20616821 (cancer vs cancer)

114218186 117151711 2 (cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer)

1- 1- cgl452095 (cancer vs cancer) cg04500239 (cancer+normal vs

118502178 154179856 7 (cancer+normal vs

cancer+normal)

cancer+normal)

1- 1- cg0493477

cgl6385939 (cancer vs cancer) (cancer vs cancer)

144513999 154179861 6

(cancer vs cancer)

1- 1- cg0289676 (cancer vs cancer) cg26799398 (cancer vs cancer)

150479509 154179996 8 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

1- 1- cg2433721 (normal vs normal) cgl4448116 (cancer+normal vs

161170110 155881944 5 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

1- 1- cg0471916 (cancer vs cancer) cgl9313373 (cancer vs cancer)

162694184 166806295 6 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- 1- cg0042608 (cancer vs cancer) cgl7095936 (cancer+normal vs

168250628 212671907 9 (cancer+normal vs

cancer+normal)

cancer+normal)

1- 1- cg0069039 (cancer vs cancer) cg22723143 (cancer vs cancer)

168940137 225697019 2 (cancer vs cancer)

(cancer vs cancer)

1- 1- cgl652481 (cancer vs cancer) cgl6508600 (cancer vs cancer)

204531383 236162295 8 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- cg0056007 (cancer vs cancer) cg00827973 (cancer+normal vs 1-61750543

204531767 2 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg2029360

cg00796611 (cancer+normal vs 1-86048540 (cancer+normal vs

206603444 9

cancer+normal) cancer+normal)

(cancer vs cancer)

1- cg0090970

cg08240383 (cancer vs cancer) 1-9211836 (cancer+normal vs

210558509 6

cancer+normal)

(normal vs normal)

1- cg0151551 (cancer vs cancer) cg20282303 (cancer vs cancer) 1-92414295

236924392 5 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- cg0644219 (cancer vs cancer) cg23610994 (cancer+normal vs 1-92414344

245925961 9 (cancer+normal vs

cancer+normal)

cancer+normal)

1- cg0342144 (cancer vs cancer) cg25199005 (cancer vs cancer) 1-92414520

246446300 0 (cancer vs cancer) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- 10- cg0663361 (cancer vs cancer) cg27408345 (cancer+normal vs

112630738 131592944 5 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

cgl857080 (cancer vs cancer)

10-698258 cg27233847 (cancer+normal vs 10-294353

0 (cancer vs cancer) cancer+normal)

10- 10- cg0751028 (cancer vs cancer) cg06467951 (cancer vs cancer)

70010790 90644018 2 (cancer vs cancer)

10- 11- cgl435979

cg27328839 (cancer vs cancer) (cancer vs cancer)

79679462 10332052 8

(cancer vs cancer)

10- 11- cg0393302 (cancer vs cancer) cgl5058572 (cancer vs cancer)

81143681 130089890 6 (cancer+normal vs cancer+normal)

11- 11- cg2166435

cgl9547141 (cancer vs cancer) (cancer vs cancer)

118313315 19841423 1

(cancer vs cancer)

(cancer vs cancer)

11- 11- cg2730987 (cancer vs cancer) cgl0407488 (cancer+normal vs

120255253 86224410 1 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

11- 12- cg2557534

cgl4057644 (cancer+normal vs (cancer vs cancer)

128327665 106703262 9

cancer+normal)

(cancer vs cancer)

11- 12- cgl581716 (cancer vs cancer) cgl7403702 (cancer+normal vs

6499575 132259591 3 (cancer vs cancer) cancer+normal)

11- 12- cg0487690 (cancer vs cancer) cg26915558 (cancer vs cancer)

68181218 95711510 5 (cancer vs cancer)

(normal vs normal) (cancer vs cancer)

12- 13- cg0855718

cgl0319629 (cancer vs cancer) (cancer vs cancer)

132285459 113420371 8

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- 13- cg0355054 (cancer vs cancer) cgl3251533 (cancer+normal vs

132286017 97787063 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 13- cg0519431

cg02764722 (cancer+normal vs (cancer+normal vs

51480175 98869706 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- 13- cgl668919 (cancer vs cancer) cg00679520 (cancer+normal vs

63133578 98869844 3 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

12- 14- cgl699657

cg04835652 (cancer vs cancer) (cancer+normal vs

94761621 91691129 1

cancer+normal)

(cancer vs cancer)

12- 14- cgl430407 (cancer vs cancer) cgl3429194 (cancer vs cancer)

96661032 91691190 3 (cancer+normal vs cancer+normal)

(cancer vs cancer)

13- 15- cg2595426 (cancer vs cancer) cg20548564 (cancer+normal vs

28240073 71092216 9 (cancer vs cancer) cancer+normal)

(normal vs normal)

(cancer vs cancer)

13- 15- cg2238912 (cancer vs cancer) cgl0752421 (cancer+normal vs

30107044 80217380 1 (cancer vs cancer) cancer+normal)

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- cg0079405 (cancer vs cancer) cgl3224075 (cancer+normal vs 16-2544909

30107081 5 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

14- cg2036418 (cancer vs cancer) cg24096323 (cancer vs cancer) 16-3139060

70129013 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

14- cg0601311

cgl8505710 (cancer vs cancer) 16-678127 (cancer+normal vs

78388728 3

cancer+normal)

(cancer vs cancer)

14- 17- cg0548576

cgl0334928 (cancer+normal vs (cancer vs cancer)

81865007 44820573 9

cancer+normal)

15- 17- cgl328206 (cancer vs cancer) cgl9838164 (cancer vs cancer)

29429054 73360252 8 (cancer vs cancer)

15- 17- cg0264783

cgl3182816 (cancer vs cancer) (cancer vs cancer)

39472102 79952861 5

(normal vs normal)

15- (cancer vs cancer) 17- cgl441939 (cancer vs cancer) cgl9606131

85215021 (cancer+normal vs 79953059 3 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

16- 17- cgl 182456 (cancer vs cancer) cg06105093 (cancer vs cancer)

19584490 80970825 4 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

16- cgl815641 (cancer vs cancer) cg02660541 (cancer+normal vs 19-4099405

3193410 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

16- cg0952055 (cancer vs cancer) cg03998598 (cancer+normal vs 2-15830021

69358580 4 (cancer vs cancer) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

17- cg0593739

cgl 1809014 (cancer+normal vs 2-18736132 (cancer vs cancer)

39067081 2

cancer+normal) (cancer+normal vs cancer+normal)

17- cg0791871

cgl2633764 (cancer vs cancer) 2-18792548 (cancer vs cancer)

43978756 2

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

17- 2- cg2727394

cgl5506894 (cancer+normal vs (cancer vs cancer)

48545805 232113244 6

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 2- cgl811329

cg05647756 (cancer+normal vs (cancer+normal vs

73805997 232135730 5

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- 2- cg0835483 (cancer vs cancer) cg08115732 (cancer+normal vs

76171794 234373030 5 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- 2- cgl671986 (cancer vs cancer) cg00204249 (cancer+normal vs

76425249 234394478 5 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- 2- cgl721230 (cancer vs cancer) cgl5732530 (cancer+normal vs

45575023 234394541 4 (cancer+normal vs cancer+normal)

cancer+normal) (cancer vs cancer)

(cancer vs cancer)

19- 2- cg2592316 (cancer vs cancer) cg24030434 (cancer+normal vs

45575134 234394645 2 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- 2- cgO 120601 (cancer vs cancer) cg23633937 (cancer+normal vs

45575142 236672749 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

2- 2- cg2070252

cgl5425061 (cancer+normal vs (cancer vs cancer)

121036351 240086087 7

cancer+normal)

(cancer vs cancer)

2- 2- _C g0844400

cg20349803 (cancer+normal vs (cancer vs cancer)

121036440 240086178 4

cancer+normal)

(cancer vs cancer)

2- cgl280410 (cancer vs cancer) cg27505472 (cancer vs cancer) 2-45557351

121036705 4 (cancer+normal vs cancer+normal)

(cancer vs cancer)

2- 22- cgl866155 (cancer vs cancer) cg25950520 (cancer vs cancer)

121036760 29441760 0 (cancer+normal vs cancer+normal)

(cancer vs cancer)

2- 3- cg0943453

cg23253991 (cancer+normal vs (cancer vs cancer)

173686677 118865026 4

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- 3- cg0580106 (cancer vs cancer) cg23337031 (cancer+normal vs

236416064 128079984 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- 3- cg0629456 (cancer vs cancer) cg00784161 (cancer+normal vs

238406432 141161580 1 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

2- 3- _C g0444157

cg06022561 (cancer vs cancer) (cancer+normal vs

242702553 188429875 7

cancer+normal)

(cancer vs cancer)

cg2492405 (cancer vs cancer)

2-3452919 cgl 1589885 (cancer+normal vs 3-32408427

1 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

2- cg2260149

cgl8769357 (cancer vs cancer) 3-45004671 (cancer+normal vs

68691913 6

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- cgl549138 (cancer vs cancer) cg27090078 (cancer+normal vs 3-72537392

85622094 5 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

2- cgl899918 (cancer vs cancer) cgl4692453 (cancer vs cancer) 4-8386198

97508486 5 (cancer+normal vs cancer+normal)

(cancer vs cancer)

3- 5- cgl646512 (cancer vs cancer) cgl5023858 (cancer vs cancer)

69812434 131408149 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

4- 5- cg0208481 (cancer vs cancer) cg03135535 (cancer+normal vs

141564017 141722174 4 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- 5- cg2319477

cg06147143 (cancer+normal vs (cancer vs cancer)

141564271 143026910 6

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

4- cg0216515 (cancer vs cancer) cgl9604703 (cancer vs cancer) 5-1546960

16261642 1 (cancer+normal vs cancer+normal) cg0247554 (cancer vs cancer)

4-1827968 cg03387103 (cancer vs cancer) 5-1596053

7 (cancer vs cancer)

(normal vs normal) (cancer vs cancer)

4- (cancer vs cancer) 6- cg0861227 (cancer vs cancer) cg26306052

48301717 (cancer+normal vs 143575123 1 (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

5- 6- cgl013420 (cancer vs cancer) cg21910416 (cancer+normal vs

126182526 143834261 4 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- 6- cgl l41252 (cancer vs cancer) cg04659396 (cancer+normal vs

131806593 170047483 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

5- cg0707727 (cancer vs cancer) cgl9003326 (cancer vs cancer) 6-25726912

60720320 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

5- cgl405933 (cancer vs cancer) cg08972357 (cancer vs cancer) 6-28875356

75009014 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- cg0827918 (cancer vs cancer) cg00415333 (cancer+normal vs 6-28875370

137493017 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- cgl000697 (cancer vs cancer) cgl3197308 (cancer+normal vs 6-30900678

32135083 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

6- cg0379004

cg03488588 (cancer vs cancer) 6-33156236 (cancer+normal vs

32135129 7

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- cg2164508 (cancer vs cancer) cgl l l08115 (cancer+normal vs 6-39072458

32135186 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- cg2122842

cg08472222 (cancer+normal vs 6-42678314 (cancer+normal vs

32135195 4

cancer+normal) cancer+normal)

(cancer vs cancer)

6- cgl077066

cg26687830 (cancer vs cancer) 6-46890102 (cancer+normal vs

32135326 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- cg0355801 (cancer vs cancer) cgl0262770 (cancer+normal vs 6-46890220

32135370 0 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

6- 7- cg2693269 (cancer vs cancer) cg07754347 (cancer+normal vs

32135379 105254235 0 (cancer vs cancer) cancer+normal)

(normal vs normal) (cancer vs cancer)

6- (cancer vs cancer) 7- cg0828146 (cancer vs cancer) cgl5070677

33288804 (cancer+normal vs 128767280 9 (cancer+normal vs cancer+normal) cancer+normal)

6- (normal vs normal) 7- cg0433475 (cancer vs cancer) cg07098566

33288891 (cancer vs cancer) 129778936 1 (cancer vs cancer) (cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

7- cg0549988

cg08309135 (cancer+normal vs 7-2473462 (cancer vs cancer)

127984393 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- cgl790762 (cancer vs cancer) cg22030483 (cancer+normal vs 7-2473529

154788856 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

7- cgl825948 (cancer vs cancer) cg03958512 (cancer vs cancer) 7-2473859

47443041 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

cgl 164625 (cancer vs cancer)

7-6689218 cg21383341 (cancer+normal vs 7-34026657

9 (cancer vs cancer) cancer+normal)

8- cg0879759 (cancer vs cancer) cgl7131553 (cancer vs cancer) 7-4751611

116676938 8 (cancer vs cancer)

(normal vs normal)

8- (cancer vs cancer) cg2764006 (cancer vs cancer) cgl l l l8198 7-4752983

128403369 (cancer+normal vs 4 (cancer vs cancer) cancer+normal)

8- cg0426149 (cancer vs cancer) cg22678977 (cancer vs cancer) 7-4753002

133689006 6 (cancer vs cancer)

(cancer vs cancer)

8- cg0831040 (cancer vs cancer)

_C g04904458 (cancer vs cancer) 7-5262452

144948315 0 (cancer+normal vs cancer+normal)

(cancer vs cancer)

8- cgl872491 (cancer vs cancer) cg21603275 (cancer+normal vs 7-75357247

41798556 2 (cancer vs cancer) cancer+normal)

(normal vs normal)

8- (normal vs normal) cg0216672

cgl9591612 7-77126994 (cancer vs cancer)

81213351 (cancer vs cancer) 5

(cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer)

8- cgl942010 (cancer vs cancer) cg05323683 (cancer+normal vs 7-98996656

95168291 1 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

8- cgl810953 (cancer vs cancer) cg02693150 (cancer vs cancer) 8-17655156

96040122 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

9- cgl227736

cg06119575 (cancer+normal vs 8-54931229 (cancer vs cancer)

108424905 6

cancer+normal)

(cancer vs cancer)

9- cg2118528 (cancer vs cancer) cgO 1062470 (cancer vs cancer) 9-14690531

34316383 3 (cancer+normal vs cancer+normal)

(cancer vs cancer)

9- cg2117434 (cancer vs cancer) cgl3763287 (cancer+normal vs 9-99450036

97856079 4 (cancer vs cancer) cancer+normal)

(cancer+normal vs (cancer+normal vs

cancer+normal) cancer+normal)

Status - Hyper Status - Hyper

(cancer vs cancer)

1- cg0094510 (cancer+normal vs cg22790257 (cancer+normal vs 1-12806027

151694108 8 cancer+normal) cancer+normal)

(cancer vs cancer)

1- 1- cg0058590 (cancer+normal vs cg06100368 (cancer+normal vs

151694123 155035388 1 cancer+normal) cancer+normal) 1- (cancer+normal vs 1- cgl718063

cgl0945917 (cancer+normal vs

156400160 cancer+normal) 201708788 1 cancer+normal)

1- (normal vs normal)

(cancer+normal vs 1- cgl602312

cgl4177914

156400432 vs cancer+normal) 201708836 (cancer+normal

2

cancer+normal)

(cancer vs cancer)

1- 1- cgl387797

cgl 1199869 (cancer+normal vs

(cancer+normal vs

171220575 201708888 4

cancer+normal) cancer+normal)

(normal vs normal)

1- 1- cg0182873

cg03739354 (cancer+normal vs

(cancer+normal vs

212839040 201708932 3 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

1- cgl437759

1-6508592 cgl5274864 (cancer+normal vs

201709135 (cancer+normal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer)

cg0891139

1-6508954 cg25097074 vs

(cancer+normal vs 1-20988590 (cancer+normal

1

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer)

(cancer+normal vs cg0090742

cg23985702 1-23668691

125619351 (normal vs normal) cancer+normal) 7

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) cg0871809

cgl8565473 (cancer+normal vs 1-23668792

128392102 (normal vs normal)

7

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- cg0486597

cg04017555 (cancer vs cancer)

(cancer+normal vs 1-40609565

61062704 6

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

11- (normal vs normal) 10- cg2468649

cg27175288 (cancer+normal vs

61062837 (cancer+normal vs 13481944 7 cancer+normal) cancer+normal)

(cancer vs cancer)

11- (normal vs normal) 10- cg0756248

cg05190577 (cancer+normal vs

61062843 (cancer+normal vs 29698470 3 cancer+normal) cancer+normal)

(cancer vs cancer)

11- (normal vs normal) 10- cgl603640

cg06282270 (cancer+normal vs

61062910 (cancer+normal vs 29699043 9 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- cg2278318

cgl7480646 (cancer vs cancer)

(cancer+normal vs 10-8091753

65405466 0

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- cgl 807262

cgO 1640437 (cancer vs cancer)

(cancer+normal vs 10-8092036

65405484 9

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- cgl580386

cg27068330 (cancer vs cancer)

(cancer+normal vs 10-8092165

65405492 9

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

12- (cancer+normal vs cgl671089

cg21470387 (cancer vs cancer)

10-8092264

112204761 cancer+normal) 4 (cancer+normal vs cancer+normal)

12- (cancer+normal vs cg0572151

cgl9746940 (cancer vs cancer)

10-8095288

114832429 cancer+normal) 5 (cancer vs cancer) (cancer+normal vs cancer+normal)

(cancer vs cancer)

12- (cancer+normal vs cgl518755 (cancer vs cancer) cgl7554126 10-8096370

114836794 cancer+normal) 0 (cancer+normal vs cancer+normal)

(cancer vs cancer)

12- (cancer+normal vs 11- cg0064847

cgl4987787 (cancer+normal vs

115105220 cancer+normal) 123525237 6

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 11- cgl008914

cg20489228 (cancer+normal vs (cancer+normal vs

115125549 130030103 5

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer+normal vs cg0247165 (cancer vs cancer) cgl8220920 11-279950

115126061 cancer+normal) 8 (cancer+normal vs cancer+normal)

(cancer vs cancer)

12- (cancer+normal vs 11- cgl827062 (cancer vs cancer) cgl5661753

49627010 cancer+normal) 31831974 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- 11- cg2684808 (cancer vs cancer) cg07731191 (cancer+normal vs

54329010 31832246 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

12- (cancer+normal vs 11- cg0584003 (cancer vs cancer) cg01473837

54409321 cancer+normal) 31832353 1 (cancer+normal vs cancer+normal)

12- (cancer+normal vs 11- cgl752818 (cancer+normal vs cg06714180

54409525 cancer+normal) 49579457 9 cancer+normal)

(cancer vs cancer) (normal vs normal)

13- cgl911366

cgl5247434 (cancer+normal vs 11-8832111 (cancer+normal vs

95201296 8

cancer+normal) cancer+normal)

13- (cancer+normal vs cg2694212 (cancer+normal vs cgl3580857 11-8832203

95201417 cancer+normal) 1 cancer+normal)

(cancer vs cancer)

15- cg2393987 (cancer+normal vs cg05739476 (cancer+normal vs 11-8832272

72072813 5 cancer+normal) cancer+normal)

(cancer vs cancer)

16- cgl704677 (cancer+normal vs cg09705457 (cancer+normal vs 11-8832283

46824143 6 cancer+normal) cancer+normal)

16- (cancer+normal vs 12- cgl932101 (cancer+normal vs cg03992149

55361816 cancer+normal) 15942969 8 cancer+normal)

16- (cancer+normal vs 12- cg2534324 (cancer+normal vs cg09662325

55363601 cancer+normal) 34756291 6 cancer+normal)

(cancer vs cancer)

17- 12- cgl535793 (cancer+normal vs cgl4527050 (cancer+normal vs

34077244 58138320 4 cancer+normal) cancer+normal)

17- (cancer+normal vs 12- cg2450219 (cancer+normal vs cgl3376404

34077293 cancer+normal) 58138329 2 cancer+normal)

(cancer vs cancer)

17- 13- cgl577370 (cancer+normal vs cg22764700 (cancer+normal vs

75798605 100633995 4 cancer+normal) cancer+normal)

17- (cancer+normal vs 15- cg0557550 (cancer+normal vs cg04763450

79455576 cancer+normal) 101262162 5 cancer+normal)

18- (cancer+normal vs 15- cg0743119 (cancer+normal vs cgl8649459

12253749 cancer+normal) 41218265 9 cancer+normal)

18- (cancer+normal vs 15- cgl683635 (cancer+normal vs cg03160145

56937906 cancer+normal) 41218333 5 cancer+normal)

2- (cancer vs cancer) 15- cg2283515 (cancer+normal vs cgl8261069

100175704 (cancer+normal vs 41218352 7 cancer+normal) cancer+normal)

(cancer vs cancer)

2- 16- cg0331566 (cancer+normal vs cg24797187 (cancer+normal vs

100175768 30759178 2 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- 16- cgl l l8117 (cancer vs cancer) cgl7165836 (cancer+normal vs

100175805 55090946 1 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

2- 16- cgl038344 (cancer+normal vs cg01381586 (cancer+normal vs

10587627 58535093 7 cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer+normal vs le- cg0806829

cgl9706900 (cancer+normal vs

12856422 cancer+normal) SS 842404 6

cancer+normal)

(cancer vs cancer)

2- (cancer+normal vs 16- cg0131390 (cancer vs cancer) cg20265661

133428502 cancer+normal) 86609963 4 (cancer+normal vs cancer+normal)

(cancer vs cancer)

2- (cancer+normal vs 16- cg0544103

cg01850449 (cancer+normal vs

133428510 cancer+normal) 89723364 9

cancer+normal)

(cancer vs cancer)

2- (cancer+normal vs 17- cg0807604

cg09622982 (cancer+normal vs

133428523 cancer+normal) 26685074 4

cancer+normal)

2- (cancer+normal vs 17- cgl 116464 (cancer+normal vs cgl9303187

172968881 cancer+normal) 47297130 9 cancer+normal)

2- (cancer+normal vs 17- cg2540086 (cancer+normal vs cgl0515731

220378996 cancer+normal) 60005610 4 cancer+normal)

2- (cancer+normal vs 19- cgl250154 (cancer+normal vs cgl8844301

220379000 cancer+normal) 13734932 6 cancer+normal)

2- (cancer+normal vs 19- cgl634522 (cancer+normal vs cg09726982

220379016 cancer+normal) 16771394 6 cancer+normal)

(normal vs normal) (cancer vs cancer)

2- 19- cgl 128293

cgl7610929 (cancer+normal vs (cancer+normal vs

220379044 17007648 6

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

2- 19- cg2454883

cg24743778 (cancer+normal vs (cancer+normal vs

220379058 17007698 3

cancer+normal) cancer+normal)

(normal vs normal)

2- cgl307671 (cancer+normal vs cgl2046414 (cancer+normal vs 19-2945492

220379199 8 cancer+normal) cancer+normal)

(cancer vs cancer)

2- 19- cg0261393 (cancer+normal vs cgl8663033 (cancer+normal vs

241034966 45395297 7 cancer+normal) cancer+normal)

(cancer vs cancer)

20- (normal vs normal) 19- cgl662003 (cancer+normal vs cg09923107

30193892 (cancer+normal vs 46097075 2 cancer+normal) cancer+normal)

(cancer vs cancer)

20- 19- cg2274751 (cancer+normal vs cg00494337 (cancer+normal vs

30194024 56348889 6 cancer+normal) cancer+normal)

(cancer vs cancer)

20- 2- cgl233424 (cancer+normal vs cgl6666964 (cancer+normal vs

37274692 169312418 7 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- 2- cg2679208

cg23884187 (cancer+normal vs (cancer+normal vs

37275069 200324879 0

cancer+normal) cancer+normal)

(cancer vs cancer)

21- (cancer+normal vs 2- cg2161604 (cancer vs cancer) cgl6706690

15135580 cancer+normal) 224467359 7 (cancer+normal vs cancer+normal) (cancer vs cancer)

21- cg0390611 (cancer+normal vs cgl7648210 (cancer+normal vs 2-33359529

46352817 5 cancer+normal) cancer+normal)

(cancer vs cancer)

3- cg0835799 (cancer+normal vs cg02607683 (cancer+normal vs 2-33359550

72149807 0 cancer+normal) cancer+normal)

(cancer vs cancer)

3- cgl464050 (cancer+normal vs cgl9996971 (cancer+normal vs 2-43823708

72149921 9 cancer+normal) cancer+normal)

(cancer vs cancer)

3- (normal vs normal) 20- cg2392928 (cancer+normal vs cg03416562

85010677 (cancer+normal vs 30605916 4 cancer+normal) cancer+normal)

(cancer vs cancer)

4- (cancer+normal vs 20- cg2134391 (cancer vs cancer) cgl6863617

100368380 cancer+normal) 46413743 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

4- 21- cgl943317 (cancer+normal vs cg09690103 (cancer+normal vs

14603924 10888524 5 cancer+normal) cancer+normal)

(cancer vs cancer)

4- (cancer+normal vs 21- cgl790085

cg05865660 (cancer+normal vs

189158066 cancer+normal) 40984777 4

cancer+normal)

(cancer vs cancer)

4- (cancer+normal vs 21- cg0844866 (cancer vs cancer) cg21054842

33062752 cancer+normal) 40984780 5 (cancer+normal vs cancer+normal)

(cancer vs cancer)

5- 3- cg2145632 (cancer+normal vs cgl9516279 (cancer+normal vs

151153922 121264201 0 cancer+normal) cancer+normal)

5- (cancer+normal vs cgl017318 (cancer+normal vs cg21242208 3-12200427

160971794 cancer+normal) 6 cancer+normal)

(cancer vs cancer)

5- 3- cg0447200 (cancer+normal vs cg27615363 (cancer+normal vs

174120078 126398566 1 cancer+normal) cancer+normal)

(cancer vs cancer)

3- cgl324255 (cancer+normal vs

6-1313730 cgl4732248 (cancer+normal vs

129062937 8 cancer+normal) cancer+normal)

6- (cancer+normal vs 3- cgl478152 (cancer+normal vs cgl l953881

137736547 cancer+normal) 129063090 1 cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 3- cg0005257 (cancer vs cancer) cg07237939 (cancer+normal vs

160769754 132843565 8 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

6- 3- cg2742751 (cancer+normal vs cg25042346 (cancer+normal vs

18990714 193922037 4 cancer+normal) cancer+normal)

(normal vs normal)

6- (cancer+normal vs 4- cgl245390

cg23363602 (cancer+normal vs

29933971 cancer+normal) 154143694 5

cancer+normal)

(cancer vs cancer)

(normal vs normal) 5- cgl419679 (cancer+normal vs

6-3053739 cg02335642

(cancer+normal vs 131705035 0 cancer+normal) cancer+normal)

(cancer vs cancer)

6- 5- cg2710758 (cancer+normal vs cg07979401 (cancer+normal vs

33739406 172386833 5 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 5- cgl356488 (cancer vs cancer) cgl8005901 (cancer+normal vs

33739558 175298869 9 (cancer+normal vs cancer+normal)

cancer+normal) (cancer vs cancer) (cancer vs cancer)

6- cgl732949

cgl6010596 (cancer+normal vs 5-65018961 (cancer+normal vs

33739607 4

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 6- cgOl 15607

cgl8120259 (cancer+normal vs

43894639 cancer+normal) 100064885 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- 6- cg0641339 (cancer vs cancer) cg06962782 (cancer+normal vs

100091575 110736865 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

7- (cancer+normal vs 6- cg0080407 (cancer vs cancer) cg02512352

151137048 cancer+normal) 110736941 8 (cancer+normal vs cancer+normal)

(cancer vs cancer)

7- (cancer+normal vs 6- cgl578589 (cancer vs cancer) cg05551889

151137192 cancer+normal) 144608500 8 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

7- 6- cg0591773

cg27135125 (cancer+normal vs (normal vs normal)

23510082 152623304 2

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

7- 6- cg0268245

cg20265043 (cancer+normal vs (normal vs normal)

23510089 152623387 7

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

7- 6- cgl202362

cg07297397 (cancer+normal vs (normal vs normal)

23510112 152623479 5

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- 6- cg2330983 (cancer vs cancer) cg22826239 (cancer+normal vs

23510123 165341320 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- cg2444094 (cancer vs cancer) cgl6466899 (cancer+normal vs 6-26224668

23510693 1 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

8- cgl267030 (cancer+normal vs cg21752469 (cancer+normal vs 6-31762630

57594909 5 cancer+normal) cancer+normal)

8- (cancer+normal vs cgl353306 (cancer+normal vs cg21037180 6-4022895

82276987 cancer+normal) 9 cancer+normal)

(cancer vs cancer)

9- (normal vs normal) cg0188132 (cancer+normal vs cg01027151 6-53660854

129372349 (cancer+normal vs 2 cancer+normal) cancer+normal)

(cancer vs cancer)

9- 7- cg0860103 (cancer+normal vs cgl4082645 (cancer+normal vs

129372478 100895999 8 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

9- (normal vs normal) 7- cg0565196

cgl9337180 (cancer+normal vs

129373499 (cancer+normal vs 130419064 0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

9- cg0369458 (cancer vs cancer) cgl4642696 (cancer+normal vs 7-2271722

129386671 0 (cancer+normal vs cancer+normal)

cancer+normal) (cancer vs cancer)

(cancer vs cancer)

9- (normal vs normal) cgl376724

cgl2777520 7-75831678 (cancer+normal vs

129387303 (cancer+normal vs 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 8- cg2290481

cgl5689835 (cancer+normal vs (cancer+normal vs

129387721 135843385 5

cancer+normal) cancer+normal)

(cancer vs cancer)

9- 9- cg2122037 (cancer+normal vs cgl3979277 (cancer+normal vs

129388281 100396777 4 cancer+normal) cancer+normal)

(cancer vs cancer)

9- 9- cg2118332 (cancer+normal vs cg04693928 (cancer+normal vs

129388668 124976219 9 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

9- cgl456087 (cancer vs cancer) cgl4100888 (cancer+normal vs 9-81871926

129445599 2 (cancer+normal vs

cancer+normal)

cancer+normal)

Status - Hypo Status - Hypo

(cancer vs cancer)

(cancer vs cancer)

1- 1- cg2405836 (cancer vs cancer) cg09896211 (cancer+normal vs

108232421 110923328 5 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- 1- cgl452095 (cancer vs cancer) cg04500239 (cancer+normal vs

118502178 154179856 7 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- 1- cg0289676 (cancer vs cancer) cgl4448116 (cancer+normal vs

161170110 154179996 8 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer+normal vs 1- cg0471916 (cancer vs cancer)

1-1611999 cg09825670

cancer+normal) 166806295 6 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- 1- cg0042608 (cancer vs cancer) cgl7095936 (cancer+normal vs

168250628 212671907 9 (cancer+normal vs

cancer+normal)

cancer+normal)

1- (cancer+normal vs 1- cgl344220 (cancer+normal vs cgl 1807529

17958884 cancer+normal) 221908735 1 cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- 1- cgl652481 (cancer vs cancer) cg00827973 (cancer+normal vs

204531767 236162295 8 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- cg0056007 (cancer vs cancer) cg00796611 (cancer+normal vs 1-61750543

206603444 2 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg2029360

cg23610994 (cancer+normal vs 1-86048540 (cancer+normal vs

245925961 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- cg0090970

cg27408345 (cancer+normal vs 1-9211836 (cancer+normal vs

112630738 6

cancer+normal) cancer+normal)

(normal vs normal)

10- (cancer+normal vs cg0151551 (cancer vs cancer) cg01709312 1-92414295

112630835 cancer+normal) 5 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

10- (cancer+normal vs cg0644219

cgl2235073 1-92414344 (cancer vs cancer)

6270423 cancer+normal) 9

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer+normal vs cg0342144 (cancer vs cancer)

10-664762 cgl 8474072 1-92414520

cancer+normal) 0 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- cg0663361 (cancer vs cancer)

10-698258 cg27233847 (cancer+normal vs

131592944 5 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

11- (cancer+normal vs 11- cg0393302 (cancer vs cancer) cg08983011

118774009 cancer+normal) 130089890 6 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- 11- cg2730987 (cancer vs cancer) cgl0407488 (cancer+normal vs

120255253 86224410 1 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 12- cgl721445

cgl4057644 (cancer+normal vs (cancer+normal vs

128327665 102216984 6

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 12- cgl962833 (cancer+normal vs cgl7403702 (cancer+normal vs

6499575 56914766 3 cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

11- (cancer+normal vs 13- cg0855718

cgl2041266 (cancer vs cancer)

75050147 cancer+normal) 113420371 8

(cancer+normal vs cancer+normal)

(cancer vs cancer)

12- 13- cg0971478 (cancer+normal vs cgl3251533 (cancer+normal vs

132286017 113422497 9 cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer+normal vs 13- cg0355054 (cancer vs cancer) cg22251684

45751145 cancer+normal) 97787063 8 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 13- cg0519431

cg02764722 (cancer+normal vs (cancer+normal vs

51480175 98869706 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- 13- cgl668919 (cancer vs cancer) cg00679520 (cancer+normal vs

63133578 98869844 3 (cancer+normal vs cancer+normal)

cancer+normal)

13- (cancer+normal vs 14- cgl825436 (cancer+normal vs cg21786786

113365464 cancer+normal) 24741821 4 cancer+normal)

13- (cancer+normal vs 14- cg2188905 (cancer+normal vs cgl0381113

24797136 cancer+normal) 73894532 4 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- 14- cgl699657

cg20548564 (cancer+normal vs (cancer+normal vs

28240073 91691129 1

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- 14- cgl430407 (cancer vs cancer) cgl0752421 (cancer+normal vs

30107044 91691190 3 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

13- 15- cg2238912

cgl3224075 (cancer+normal vs (cancer vs cancer)

30107081 80217380 1

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

14- (cancer+normal vs cg0079405

cgl8519050 16-2544909 (cancer vs cancer)

105181796 cancer+normal) 5

(cancer+normal vs cancer+normal)

(cancer vs cancer)

14- (cancer+normal vs 16- cg0368115

cgl4144229 (cancer+normal vs

69136587 cancer+normal) 29857167 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

14- cg2036418 (cancer vs cancer) cgl0334928 (cancer+normal vs 16-3139060

81865007 7 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

(cancer vs cancer)

15- (cancer vs cancer) cg0601311

cgl9606131 16-678127 (cancer+normal vs

85215021 (cancer+normal vs 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16- 17- cg0398971

cg02660541 (cancer+normal vs (cancer+normal vs

3193410 80970799 1

cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer+normal vs 17- cgl 182456 (cancer vs cancer) cg09479650

85578516 cancer+normal) 80970825 4 (cancer+normal vs cancer+normal)

16- (cancer+normal vs 17- cgl082073 (cancer+normal vs cglOl 19288

87442996 cancer+normal) 80970892 6 cancer+normal)

(cancer vs cancer)

17- (cancer+normal vs cg0186236

cg00748958 17-8928028 (cancer+normal vs

30348814 cancer+normal) 3

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- cgl815641 (cancer vs cancer) cgl 1809014 (cancer+normal vs 19-4099405

39067081 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

17- 2- cg0075460 (cancer+normal vs cgl5506894 (cancer+normal vs

48545805 161230046 4 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

17- cg0593739

cg05647756 (cancer+normal vs 2-18736132 (cancer vs cancer)

73805997 2

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

17- 2- cg2662795 (cancer+normal vs cg08115732 (cancer+normal vs

76171794 202004766 6 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

17- 2- cg2727394

cg00204249 (cancer+normal vs (cancer vs cancer)

76425249 232113244 6

cancer+normal) (cancer+normal vs cancer+normal)

(normal vs normal) (cancer vs cancer)

17- 2- cgl811329

cg02059952 (cancer+normal vs (cancer+normal vs

8384595 232135730 5

cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

17- 2- cg0835483 (cancer vs cancer) cg06557376 (cancer+normal vs

8384607 234373030 5 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

19- (cancer+normal vs 2- cgl671986 (cancer vs cancer) cg08692295

45574210 cancer+normal) 234394478 5 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- 2- cgl721230 (cancer vs cancer) cgl5732530 (cancer+normal vs

45575023 234394541 4 (cancer+normal vs cancer+normal)

cancer+normal)

19- (cancer vs cancer) 2- cg2592316 (cancer vs cancer) cg24030434

45575134 (cancer+normal vs 234394645 2 (cancer vs cancer) cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- 2- cgO 120601 (cancer vs cancer) cg23633937 (cancer+normal vs

45575142 236672749 7 (cancer+normal vs cancer+normal)

cancer+normal)

19- (cancer+normal vs 2- cgl912508 (cancer+normal vs cg27077312

45575442 cancer+normal) 242219370 1 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cgl328658

cgl5425061 (cancer+normal vs 2-37883934 (cancer+normal vs

121036351 2

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- cgl280410 (cancer vs cancer) cg20349803 (cancer+normal vs 2-45557351

121036440 4 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

2- cgl399778 (cancer+normal vs cg23087358 (cancer+normal vs 2-46593223

121745872 8 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- 22- cgl866155 (cancer vs cancer) cg23253991 (cancer+normal vs

173686677 29441760 0 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- 3- cg0580106 (cancer vs cancer) cg23337031 (cancer+normal vs

236416064 128079984 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- 3- cg2576941

cg00784161 (cancer+normal vs (cancer+normal vs

238406432 132077190 2

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer+normal vs 3- cg0629456 (cancer vs cancer) cgl7801295

241640826 cancer+normal) 141161580 1 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- cgl 143172

2-3452919 cgl 1589885 (cancer+normal vs (cancer+normal vs

149126842 3

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer+normal vs 3- _C g0444157

cg23892924 (cancer+normal vs

46909601 cancer+normal) 188429875 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cg2260149

cg27090078 (cancer+normal vs 3-45004671 (cancer+normal vs

85622094 6

cancer+normal) cancer+normal)

(cancer vs cancer)

22- (cancer+normal vs cgl549138 (cancer vs cancer) cg24489344 3-72537392

46457998 cancer+normal) 5 (cancer+normal vs cancer+normal)

3- (cancer+normal vs 4- cg0095769 (cancer+normal vs cg21552014

146026497 cancer+normal) 121991345 8 cancer+normal)

(cancer vs cancer)

4- 4- cgl083265 (cancer+normal vs cg03135535 (cancer+normal vs

141564017 121991576 5 cancer+normal) cancer+normal)

(cancer vs cancer)

4- 4- cgl706115 (cancer+normal vs cg06147143 (cancer+normal vs

141564271 184941494 6 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

4- (cancer vs cancer) cg0820607

cg26306052 4-8386188 (cancer+normal vs

48301717 (cancer+normal vs 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- cgl899918

cg21910416 (cancer+normal vs 4-8386198 (cancer vs cancer)

126182526 5

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- 5- cgl646512 (cancer vs cancer) cg04659396 (cancer+normal vs

131806593 131408149 9 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

5- 5- cg2320193 (cancer+normal vs cg09102257 (cancer+normal vs

137803102 134451535 8 cancer+normal) cancer+normal)

(cancer vs cancer)

5- (cancer+normal vs 5- cg0208481 (cancer vs cancer) cg02077216

57753951 cancer+normal) 141722174 4 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(normal vs normal)

5- 5- cg2319477 (cancer vs cancer) cg07209550 (cancer+normal vs

79070077 143026910 6 (cancer+normal vs cancer+normal)

cancer+normal)

6- (cancer+normal vs cg2218597 (cancer+normal vs cgl5972264 5-1518133

11279680 cancer+normal) 7 cancer+normal)

(cancer vs cancer)

6- cg2693436 (cancer+normal vs cg00415333 (cancer+normal vs 5-1519265

137493017 2 cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs cg0216515 (cancer vs cancer) cgl7527814 5-1546960

32135061 cancer+normal) 1 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 6- cgl796985

cgl3197308 (cancer+normal vs (cancer+normal vs

32135083 108615613 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 6- cg0861227 (cancer vs cancer) cgl l l08115 (cancer+normal vs

32135186 143575123 1 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

(cancer vs cancer)

6- 6- cgl013420 (cancer vs cancer) cg08472222 (cancer+normal vs

32135195 143834261 4 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 6- cgl l41252 (cancer vs cancer) cgl0262770 (cancer+normal vs

32135370 170047483 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- cg0707727 (cancer vs cancer) cg07754347 (cancer+normal vs 6-25726912

32135379 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs cgl405933 (cancer vs cancer) cg09597192 6-28875356

32141591 cancer+normal) 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs cg0827918 (cancer vs cancer) cg05147195 6-28875370

33288734 cancer+normal) 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(normal vs normal)

6- cgl000697 (cancer vs cancer) cgl4499959 (cancer+normal vs 6-30900678

33288773 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs cg0379004

cg21350498 6-33156236 (cancer+normal vs

33288785 cancer+normal) 7

cancer+normal)

6- (normal vs normal) cg2164508 (cancer vs cancer) cgl5070677 6-39072458

33288804 (cancer vs cancer) 9 (cancer vs cancer) (cancer+normal vs (cancer+normal vs

cancer+normal) cancer+normal)

6- (cancer vs cancer)

(cancer+normal vs cg0085957

cgl 8704865 6-39159259

33288851 (cancer+normal vs

cancer+normal) 4

cancer+normal)

(normal vs normal)

6- (cancer vs cancer)

(cancer vs cancer) cg2122842

cg07098566 6-42678314

33288891 (cancer+normal vs

(cancer+normal vs 4

cancer+normal) cancer+normal)

6- (cancer vs cancer)

(cancer+normal vs cgl077066

cg03243551 6-46890102

33288941 (cancer+normal vs

cancer+normal) 2

cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs cg0355801 (cancer vs cancer) cgl4199833 6-46890220

33288964 cancer+normal) 0 (cancer+normal vs

cancer+normal)

(normal vs normal)

6- cgl397536

cg20849032 (cancer+normal vs

(cancer+normal vs 6-46890512

33289243 2 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- 7- cg0828146 (cancer vs cancer) cg08309135 (cancer+normal vs

127984393 128767280 9 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- 7- cg0433475 (cancer vs cancer) cg22030483 (cancer+normal vs

154788856 129778936 1 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer+normal vs cgl790762

7-2030229 (cancer vs cancer) cg05434287 7-2473529

cancer+normal) 8 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(normal vs normal)

cgl825948

7-4169604 (cancer vs cancer) cg08250787 (cancer+normal vs 7-2473859

7 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

cg2559410

7-4169630 cgl3818127 (cancer+normal vs

(cancer+normal vs 7-4786943

0 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer+normal vs cg0831040

7-609693 (cancer vs cancer) cg04666346 7-5262452

cancer+normal) 0 (cancer+normal vs

cancer+normal)

(cancer vs cancer) (normal vs normal) cgl527737

7-6689218 cg21383341 (cancer+normal vs 7-5272208 (cancer+normal vs

8

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

8- (cancer vs cancer) cg2009945

cgl l l l8198 7-5272275

128403369 (cancer+normal vs

(cancer+normal vs 8

cancer+normal) cancer+normal)

(cancer vs cancer)

8- (cancer+normal vs cgl942010

cg26185884 (cancer vs cancer)

7-98996656

144568432 cancer+normal) 1 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- cgl810953 (cancer vs cancer) cg21603275 (cancer+normal vs 8-17655156

41798556 7 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

8- (cancer+normal vs cg2633366

cgl3475877 8-28625366

56882373 (cancer+normal vs

cancer+normal) 0

cancer+normal)

8- cg05323683 (cancer vs cancer) 8-28950303 cg0723765 (cancer+normal vs 95168291 (cancer+normal vs 3 cancer+normal) cancer+normal)

(cancer vs cancer)

9- 9- cgl341379 (cancer+normal vs cg06119575 (cancer+normal vs

108424905 126182794 2 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

9- cg2118528 (cancer vs cancer) cgl3763287 (cancer+normal vs 9-14690531

97856079 3 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal) (normal vs normal)

Status - Hyper Status - Hyper

1- 1- cgl l73130

cg07817024 (normal vs normal) (normal vs normal)

119535500 161008542 0

1- 1- cgl242028

cg24434800 (normal vs normal) (normal vs normal)

119542295 173990399 3

(normal vs normal)

1- 1- cg0513515

cg03739354 (cancer+normal vs (normal vs normal)

212839040 184355420 6

cancer+normal)

(cancer vs cancer)

(normal vs normal)

1- (normal vs normal) 1- cgl602312

cg03599978 (cancer+normal vs

219834537 (cancer+normal vs 201708836 2

cancer+normal) cancer+normal)

(normal vs normal)

1- 1- cgl437759

cg22444124 (normal vs normal) (cancer+normal vs

226867960 201709135 6

cancer+normal)

1- cgl696696

1-6064094 cg03895593 (normal vs normal) (normal vs normal)

201915989 2

10- 1- cg0325491

cgl8736101 (normal vs normal) (normal vs normal)

126043549 201978949 6

(cancer vs cancer) (cancer vs cancer)

10- cg0090742

_C gl4947429 (normal vs normal) 1-23668691 (normal vs normal)

28036151 7

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer)

11- (normal vs normal) cg0871809

cg27175288 1-23668792 (normal vs normal)

61062837 (cancer+normal vs 7

(cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

11- (normal vs normal) 1- cg0282030

cg05190577 (normal vs normal)

61062843 (cancer+normal vs 241802556 9

cancer+normal)

11- 1- cg2250271

cg07402729 (normal vs normal) (normal vs normal)

61062902 247171572 5

(cancer vs cancer)

11- (normal vs normal) cgl962107

cg06282270 1-26800075 (normal vs normal)

61062910 (cancer+normal vs 6

cancer+normal)

11- cg2459177

cg01698298 (normal vs normal) 1-45082704 (normal vs normal)

61062964 0

11- cgl280992

cg23619769 (normal vs normal) 1-8042702 (normal vs normal)

71952356 5

11- cg2294957

cg26668837 (normal vs normal) 1-85667951 (normal vs normal)

8615356 8

12- 10- cg0586715

cg01181415 (normal vs normal) (normal vs normal)

16757954 52835002 4

12- 10- cg2666739

cgl0143811 (normal vs normal) (normal vs normal)

16757985 93392399 5

12- 11- cg2285532

cgl8540674 (normal vs normal) (normal vs normal)

54405379 19368277 5 11- cg2527067

12-570155 cg26388816 (normal vs normal) (normal vs normal)

61735789 0

13- 11- cg2289714

cg24154053 (normal vs normal) (normal vs normal)

37004990 64577338 1

(normal vs normal)

15- cgl911366

cgl 1092048 (normal vs normal) 11-8832111 (cancer+normal vs

37180325 8

cancer+normal)

15- 12- cg0063281

cg08450752 (normal vs normal) (normal vs normal)

73611451 108078821 1

16- cgl858438

cg08511886 (normal vs normal) 12-4384879 (normal vs normal)

60233305 7

16- 12- cg2450290

cg03314029 (normal vs normal) (normal vs normal)

88496788 53399544 4

16- 12- cg2182218

cg07215504 (normal vs normal) (normal vs normal)

88497007 66286141 7

17- 12- cgl344296

cg02407342 (normal vs normal) (normal vs normal)

42988784 68044208 9

17- 12- cg0917188

cg02642822 (normal vs normal) (normal vs normal)

46666926 75874499 2

17- 12- cgl887773

cg09704116 (normal vs normal) (normal vs normal)

46666958 86267881 7

17- 14- cg2319786

cgl0588962 (normal vs normal) (normal vs normal)

46667587 100659756 7

17- 14- cgl 170058

cg21242356 (normal vs normal) (normal vs normal)

46667683 50088544 4

17- 14- cg0163963

cg25660390 (normal vs normal) (normal vs normal)

73073700 57859336 5

17- 14- cg0925773

cgl6757821 (normal vs normal) (normal vs normal)

73073940 93581049 5

19- 16- cg0597933

cg00689651 (normal vs normal) (normal vs normal)

13209548 30709162 2

19- 16- cgl006753

cgl7431280 (normal vs normal) (normal vs normal)

47507461 87351824 8

19- 17- cg2089835

cg24122124 (normal vs normal) (normal vs normal)

5339092 16947406 8

2- cg0552981

cg06292076 (normal vs normal) 17-4802735 (normal vs normal)

105464104 6

2- 17- cg0852732

cgl0330950 (normal vs normal) (normal vs normal)

119589844 54655325 4

2- 18- cgl760245

cgl0543450 (normal vs normal) (normal vs normal)

119592325 60985645 1

2- 19- cg0797660

cg02958634 (normal vs normal) (normal vs normal)

119594696 10444506 3

2- cg2305722

cgl8093372 (normal vs normal) 19-1356315 (normal vs normal)

119607603 0

2- (cancer vs cancer) 19- cgl209927

cg25317460 (normal vs normal)

119608121 (normal vs normal) 40732518 9

2- 19- cg2363559

cg21301942 (normal vs normal) (normal vs normal)

119608651 45281006 9

2- cg2120165

cgl 1236727 (normal vs normal) 19-5624574 (normal vs normal)

119609592 7

2- 19- cgl460337

cgl3367169 (normal vs normal) (normal vs normal)

119609642 57831549 5

2- cgl512475

cgl2336777 (normal vs normal) 2-17699904 (normal vs normal)

145210222 7

2- 2- cgl030545

cg20509869 (normal vs normal) (normal vs normal)

220375605 177043427 1

(normal vs normal)

2- 2- cg0787538

cgl7610929 (cancer+normal vs (normal vs normal)

220379044 190044601 5

cancer+normal)

2- cg24743778 (normal vs normal) 2- cg2277447 (normal vs normal) 220379058 (cancer+normal vs 190044636 2

cancer+normal)

(normal vs normal)

2- 2- cg2466331

cgl2046414 (cancer+normal vs (normal vs normal)

220379199 191224886 1

cancer+normal)

20- 2- cgl728864

cgl4498592 (normal vs normal) (normal vs normal)

62092502 196943333 3

22- cg0317702

cg00241712 (normal vs normal) 2-28112917 (normal vs normal) 43116077 5

3- cg0096863

cg06346667 (normal vs normal) 2-43450965 (normal vs normal)

137488697 8

(cancer vs cancer) (cancer vs cancer)

3- (normal vs normal) cgl687664 (normal vs normal) cg09095222 2-43451842

157816094 (cancer+normal vs 7 (cancer+normal vs

cancer+normal) cancer+normal)

3- cg0819365

cgl8482112 (normal vs normal) 2-43451868 (normal vs normal)

184209105 0

3- cgl 171475

cg00786761 (normal vs normal) 2-96926568 (normal vs normal)

184209224 2

3- 20- cgl952571

cg24931191 (normal vs normal) (normal vs normal)

36248859 43160249 7

(cancer vs cancer)

3- (normal vs normal) 20- cgl587154

cg03416562 (normal vs normal)

85010677 (cancer+normal vs 52211744 4

cancer+normal)

3- 21- cgl478546

cg20276377 (normal vs normal) (normal vs normal)

99595026 38362725 4

3- 21- cg0616771

cg22092811 (normal vs normal) (normal vs normal)

99595145 38362727 9

4- 22- cgl081973

cg00332153 (normal vs normal) (normal vs normal)

102712010 24237672 3

4- 3- cg0087286

cg27140058 (normal vs normal) (normal vs normal)

102712216 112770545 5

4- 3- cgl351283

cgl4855874 (normal vs normal) (normal vs normal)

102712397 149530294 0

4- 3- cg0639825

cgl7929238 (normal vs normal) (normal vs normal)

111545628 184033620 1

5- cg0037170

cg01876548 (normal vs normal) 3-25469125 (normal vs normal)

124126863 2

5- cg0285592

cg08763705 (normal vs normal) 3-50402563 (normal vs normal)

139525657 4

5- cg2415921

cg08506654 (normal vs normal) 3-50402751 (normal vs normal)

172673098 4

4- cgl 153794

5-1875548 cgl7629929 (normal vs normal) (normal vs normal)

139773369 6

(normal vs normal)

4- cgl245390

5-1875611 cgl4024788 (normal vs normal) (cancer+normal vs

154143694 5

cancer+normal) cg2437111

5-1875886 cgl8856388 (normal vs normal) 4-24913973 (normal vs normal)

4

5- cgl080083

cg03889507 (normal vs normal) 4-57521657 (normal vs normal)

33309433 3

cg2485254

5-3589702 cg01549315 (normal vs normal) 4-57522632 (normal vs normal)

8

cg0884955

5-3592435 cgl9814981 (normal vs normal) 5-15538923 (normal vs normal)

8

cg2489213

5-3592466 cg09382127 (normal vs normal) 5-35618383 (normal vs normal)

9

5- cg2664665

cgl7780731 (normal vs normal) 5-55776364 (normal vs normal)

67483678 9

6- cgl2646820 (normal vs normal) 5-60921891 cgl363424 (normal vs normal) 13924406 2

6- cgl367207

cg05065239 (normal vs normal) 5-87439429 (normal vs normal)

18990650 8

(normal vs normal)

6- cgl083014

cg25042346 (cancer+normal vs 5-87440121 (normal vs normal)

18990714 5

cancer+normal)

(cancer vs cancer)

(normal vs normal) 6- cgl813696

6-3053739 cg02335642 (normal vs normal)

(cancer+normal vs 139013146 3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 6- cg0591773

cg04276508 (normal vs normal) (normal vs normal)

50819054 152623304 2

(cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 6- cg0268245

cg07436152 (normal vs normal) (normal vs normal)

50819236 152623387 7

(cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 6- cgl202362

cg07143470 (normal vs normal) (normal vs normal)

56111812 152623479 5

(cancer+normal vs cancer+normal) cg0153310

6-5994588 cg20421446 (normal vs normal) 6-27101662 (normal vs normal)

8

7- cg0773911

cg24525457 (normal vs normal) 6-27255829 (normal vs normal)

100091255 3

7- cgl973553

cg03113878 (normal vs normal) 6-33560953 (normal vs normal)

100091364 8

7- cg0316675

cg20884887 (normal vs normal) 6-38683221 (normal vs normal)

27208285 3

7- cg0649315

cg27157482 (normal vs normal) 6-42859023 (normal vs normal)

27215606 4

7- cg0749535

cg02483701 (normal vs normal) 6-43021181 (normal vs normal)

27215610 7

7- cgl438695

cgl0724867 (normal vs normal) 6-5999186 (normal vs normal)

27218867 1

7- cg2440121

cg05517976 (normal vs normal) 6-72892597 (normal vs normal)

27220049 9

7- cgl665533

cg00705992 (normal vs normal) 6-72892901 (normal vs normal)

27226329 8

8- 7- cgl250765

cg00467244 (normal vs normal) (normal vs normal)

142428240 100465051 5

8- 7- cg0208793

cgl0423052 (normal vs normal) (normal vs normal)

22562469 134576290 1

8- cgl799413

cgl5416643 (normal vs normal) 7-27187556 (normal vs normal)

24815840 9

8- cgl211008

cg09557462 (normal vs normal) 7-27187691 (normal vs normal)

26721736 7

(normal vs normal)

8- cg0194286

cg21752469 (cancer+normal vs 7-99769432 (normal vs normal)

57594909 3

cancer+normal)

8- 8- cg2368655

cg21935519 (normal vs normal) (normal vs normal)

66472955 131961316 6

(cancer vs cancer)

9- (normal vs normal) 8- cg0525135

cg01027151 (normal vs normal)

129372349 (cancer+normal vs 144161874 9

cancer+normal)

9- cgl5751452 (normal vs normal) 8- cg0211085 (cancer vs cancer) 129372974 145028222 8 (normal vs normal)

(cancer vs cancer)

9- (normal vs normal) 8- cg0559530

cgl9337180 (normal vs normal)

129373499 (cancer+normal vs 145028230 1

cancer+normal)

(cancer vs cancer)

9- (normal vs normal) 9- cg0795442

cgl2777520 (normal vs normal)

129387303 (cancer+normal vs 130741881 3

cancer+normal)

Status - Hypo Status - Hypo

1- cg2272812

1-1144658 cg02296931 (normal vs normal) (normal vs normal)

112299491 8

1- 1- cg0086241

cg04095826 (normal vs normal) (normal vs normal)

230457906 203763196 7

1- cg2405010

cg05266497 (normal vs normal) 1-6501240 (normal vs normal)

230457961 9

10- cgl l l6139

1-2827833 cgl5356461 (normal vs normal) (normal vs normal)

34998341 6

10- 11- cgl338564

cg02638348 (normal vs normal) (normal vs normal)

134692167 116612907 4

10- 11- cg0822860

cg03653518 (normal vs normal) (normal vs normal)

134692406 120911604 0

10- 11- cg2508057

cg01307776 (normal vs normal) (normal vs normal)

134774781 33730665 1

10- 11- cg0510027

cgl5595525 (normal vs normal) (normal vs normal)

134944446 78075960 9

10- 11- cg2518960

cgl4636714 (normal vs normal) (normal vs normal)

135018298 96117844 8

10- 12- cg0060562

cg07660114 (normal vs normal) (normal vs normal)

1531034 101413143 8

10- 12- cgl886086

cg01341216 (normal vs normal) (normal vs normal)

1767830 117588951 8

10- 12- cg2477649

cg06655291 (normal vs normal) (normal vs normal)

30980898 12421246 8

11- 12- cg2280843

cg26682904 (normal vs normal) (normal vs normal)

101787410 130711711 8

11- 12- cg0688745

cg25615926 (normal vs normal) (normal vs normal)

110862216 24850642 4

12- 12- cg2174600

cg26467753 (normal vs normal) (normal vs normal)

10339077 53610772 1

12- 12- cg0659515

cg25368917 (normal vs normal) (normal vs normal)

124788627 94619636 3

12- 13- cg2027956

cg03024698 (normal vs normal) (normal vs normal)

124788791 113356724 1

12- 13- cg0099002

cg05712979 (normal vs normal) (normal vs normal)

124788814 113357112 0

12- 13- cg0824728

cgl8672389 (normal vs normal) (normal vs normal)

124789036 113400754 9

(normal vs normal)

(cancer vs cancer)

12- 13- cg0855718

cgl0158717 (normal vs normal) (cancer vs cancer)

133380471 113420371 8

(cancer+normal vs cancer+normal)

13- 13- cgl874806

cg03555276 (normal vs normal) (normal vs normal) 113260139 113423268 4

13- 13- cg2116396

cg25506686 (normal vs normal) (normal vs normal)

74780742 113425298 9

14- 13- cg0339957

cg23112821 (normal vs normal) (normal vs normal)

100658902 19759420 4

14- 14- cgl973754

cgl3276428 (normal vs normal) (normal vs normal)

105048531 100305758 0 14- 14- cgl640042

cg05055001 (normal vs normal) (normal vs normal)

30649039 35447884 5

(normal vs normal)

15- (cancer vs cancer) 14- cg0679668

cgl9606131 (normal vs normal)

85215021 (cancer+normal vs 70757518 2

cancer+normal)

16- 14- cg0154691

cg04727521 (normal vs normal) (normal vs normal) 1154951 75522151 9

16- 14- cg2621580

cg27239473 (normal vs normal) (normal vs normal)

1478504 89254566 7

16- 15- cgl316869

cg06186992 (normal vs normal) (normal vs normal)

49525139 77481069 8

(normal vs normal)

(cancer vs cancer)

16- 15- cg2238912

cg02101892 (normal vs normal) (cancer vs cancer)

49525225 80217380 1

(cancer+normal vs cancer+normal)

16- 15- cg0944901

cg07565228 (normal vs normal) (normal vs normal)

75148743 93995636 2

16- cg0342090

cg06678912 (normal vs normal) 16-4717772 (normal vs normal)

86756576 7

16- 16- cg2662402

cg27271738 (normal vs normal) (normal vs normal)

88166905 56995739 1

17- 16- cg0516785

cgl6777510 (normal vs normal) (normal vs normal)

40440022 86121574 7

17- 17- cg0240077

cg02172058 (normal vs normal) (normal vs normal) 58499911 13502304 3

17- 17- cgl770393

cg09340279 (normal vs normal) (normal vs normal)

80278947 39136589 4

(normal vs normal)

17- 17- cg2533360

cg02059952 (cancer+normal vs (normal vs normal)

8384595 62778230 2

cancer+normal)

(normal vs normal)

17- 17- cgl874888

cg06557376 (cancer+normal vs (normal vs normal)

8384607 76102450 8

cancer+normal)

17- 17- cgl683133

cg07335619 (normal vs normal) (normal vs normal) 8814822 79047681 1

18- 19- cg0991451

cg07277756 (normal vs normal) (normal vs normal)

10589357 18359562 3

18- 19- cgl542704

cg23865597 (normal vs normal) (normal vs normal)

46987786 39696134 0

(normal vs normal)

(cancer vs cancer)

18- cg0593739

cg01514831 (normal vs normal) 2-18736132 (cancer vs cancer)

77236335

(cancer+normal vs cancer+normal)

(normal vs normal)

(normal vs normal) (cancer vs cancer)

2- ₉ . cg2727394

cg23087358 (cancer+normal vs f. (cancer vs cancer)

121745872 232113244 o

cancer+normal) (cancer+normal vs

cancer+normal)

2- cg2073199

cgl 3806767 (normal vs normal) 2-25190741 (normal vs normal)

162164127 9

2- cgl340917 (normal vs normal) cg00768195 (normal vs normal) 2-61352525

169927922 4 (cancer vs cancer)

2- cgl537141

cg07215298 (normal vs normal) 2-95538610 (normal vs normal)

240040219 8

2- 22- cg2382548

cgl7249452 (normal vs normal) (normal vs normal)

240531507 31336785 0

2- 22- cgl795674

cg22594737 (normal vs normal) (normal vs normal)

241640444 37491595 7 2- 22- cg2712083

cgl 1503661 (normal vs normal) (normal vs normal)

242791120 43193524 3

2- 3- cg0249320

cg21585640 (normal vs normal) (normal vs normal)

98351171 100516031 5

cgl556420

20-170368 cg02301189 (normal vs normal) 3-28386748 (normal vs normal)

7

20- cgl630622

cg04343045 (normal vs normal) 3-46985840 (normal vs normal)

32859896 8

20- cg0263648

cgl8082354 (normal vs normal) 3-52802660 (normal vs normal) 5896145 8

21- cg2115442

cg00660452 (normal vs normal) 3-53161967 (normal vs normal)

37756397 6

21- cg0710059

cg22391205 (normal vs normal) 3-56503840 (normal vs normal)

47458587 5

3- cg2760661

cg04554240 (normal vs normal) 3-61826848 (normal vs normal)

138170552 8

3- 4- cgl079266

cg05301252 (normal vs normal) (normal vs normal)

138170939 125369980 0

3- 4- cg2717935

cg04855678 (normal vs normal) (normal vs normal)

195946921 156364125 3

3- 4- cg2293553

cg08489309 (normal vs normal) (normal vs normal)

54067965 184441284 3

3- cgl327964

cg07777540 (normal vs normal) 4-25071580 (normal vs normal)

64524911 3

3- cgl869566

cgl3491005 (normal vs normal) 4-42504518 (normal vs normal)

96494778 5

5- cg2666031

4-1049922 cg03744197 (normal vs normal) (normal vs normal)

110077272 6

4- 5- cgl618600

cg09527687 (normal vs normal) (normal vs normal)

153549242 159448398 1

5- cgl l l5140

4-1994462 cg04996238 (normal vs normal) (normal vs normal)

159820339 2

(normal vs normal)

4- (cancer vs cancer) cg0546290

cg26306052 5-54922354 (normal vs normal)

48301717 (cancer+normal vs 5

cancer+normal)

(normal vs normal)

5- cg0471963

cg09102257 (cancer+normal vs 5-73872294 (normal vs normal)

137803102 4

cancer+normal)

5- cg0239717

cg06825415 (normal vs normal) 5-9348193 (normal vs normal)

13960359 9

6- cgl701614

5-160335 cg26612409 (normal vs normal) (normal vs normal)

141520754 5

(normal vs normal)

6- cgl013420 (cancer vs cancer)

5-160518 _C g09444426 (normal vs normal)

143834261 4 (cancer+normal vs

cancer+normal)

5- 6- cg0440904

cg05941376 (normal vs normal) (normal vs normal)

167836834 146203625 8

5- cg0409713

cg07841353 (normal vs normal) 6-15298461 (normal vs normal)

177980755 1

5- 6- cgl005941

cg05606376 (normal vs normal) (normal vs normal)

38446192 157210471 0

(normal vs normal)

5- cg0270490

cg07209550 (cancer+normal vs 6-27116113 (normal vs normal)

79070077 7

cancer+normal)

6- _C g0894444

cg02084214 (normal vs normal) 6-28496405 (normal vs normal)

15243923 3

6- cg0524172

cg08839808 (normal vs normal) 6-28542563 (normal vs normal)

156983304 1

6- cg00269725 (normal vs normal) 6-39637466 cgl547898 (normal vs normal) 156983315 1

6- cg0252483

cg00780364 (normal vs normal) 6-41934765 (normal vs normal)

32180238 4

6- cg0721377

cg01873637 (normal vs normal) 6-85328105 (normal vs normal)

32180305 1

6- cg0182312

cgl6315106 (normal vs normal) 6-97752691 (normal vs normal)

33288561 0

(normal vs normal)

6- 7- cg2030167

cgl4499959 (cancer+normal vs (normal vs normal)

33288773 115977777 7

cancer+normal)

(normal vs normal)

6- (cancer vs cancer) 7- cg2551531

cgl5070677 (normal vs normal)

33288804 (cancer+normal vs 116164108 7

cancer+normal)

(normal vs normal)

6- (cancer vs cancer) 7- cg0328029

cg07098566 (normal vs normal)

33288891 (cancer+normal vs 116659609 9

cancer+normal)

6- 7- cg0676839

cgl9384106 (normal vs normal) (normal vs normal)

33289202 127589252 3

(normal vs normal)

6- 7- cgl 148002

cg20849032 (cancer+normal vs (normal vs normal)

33289243 142723312 9

cancer+normal)

7- 7- cg2096402

cgl5176338 (normal vs normal) (normal vs normal)

148951560 156434403 1

7- cgl676208

7-1632265 cg01669161 (normal vs normal) (normal vs normal)

158551108 5

(normal vs normal) cgl527737

7-1976964 cgO 1178603 (normal vs normal) 7-5272208 (cancer+normal vs

8

cancer+normal)

(normal vs normal)

cgl023395

7-4169604 cg08250787 (cancer+normal vs 7-56131519 (normal vs normal)

3

cancer+normal)

(normal vs normal)

cgl314772

7-4169630 cgl3818127 (cancer+normal vs 7-65941812 (normal vs normal)

1

cancer+normal)

(normal vs normal)

7- cg0216672

cg06931356 (normal vs normal) 7-77126994 (cancer vs cancer)

43575891 5

(cancer vs cancer)

8- cgl939625 (normal vs normal) cgl5149205 (normal vs normal) 7-77584545

126403700 3 (cancer vs cancer)

(normal vs normal)

8- (cancer vs cancer) 8- cgl408488

cgl l l l8198 (normal vs normal)

128403369 (cancer+normal vs 117777782 8

cancer+normal)

8- cg0357944

8-328499 cg20223392 (normal vs normal) (normal vs normal)

126216633 6

8- 8- cgl546356

cg04418647 (normal vs normal) (normal vs normal)

50653901 134224890 3

8- 8- cg0141733

cgl0951117 (normal vs normal) (normal vs normal)

50653939 135813202 9

8- cg2162297

cg23244463 (normal vs normal) 8-30240920 (normal vs normal)

73848937 7

8- cgl664809 (normal vs normal) cg08294044 (normal vs normal) 8-62412760

73849039 4 (cancer vs cancer)

8- (normal vs normal) cg0723450

cgl9591612 8-82395948 (normal vs normal)

81213351 (cancer vs cancer) 8

9- cg2201340

cgl3604154 (normal vs normal) 8-93487304 (normal vs normal)

129349764 7

9- cgOl 18846

cgl3706315 (normal vs normal) 8-93581364 (normal vs normal)

134724316 6 LUSC (cancer vs

BrCaG (cancer vs cancer)

cancer)

Status - Hyper Status - Hyper

(cancer vs cancer)

1- (normal vs normal) cg0722196

cgl7935811 1-18969717 (cancer vs cancer)

12678641 (cancer+normal vs 7

cancer+normal)

(cancer vs cancer)

1- (normal vs normal) 1- cg2447485

cg01346152 (cancer vs cancer)

12678761 (cancer+normal vs 230850050 2

cancer+normal)

(cancer vs cancer)

1- (normal vs normal) cg0365570

cgl0985914 1-24885664 (cancer vs cancer)

212769641 (cancer+normal vs 1

cancer+normal)

1- cgl733920

cg06718763 (cancer vs cancer) 1-33160900 (cancer vs cancer)

24828586 2

1- cgl388095

cgl2813724 (cancer vs cancer) 1-44884096 (cancer vs cancer)

26690537 0

(cancer vs cancer)

1- (cancer vs cancer) cgl254863

cgl2610832 1-44884109 (cancer vs cancer)

27894955 (cancer+normal vs 4

cancer+normal)

(cancer vs cancer)

1- (normal vs normal) cgl l71582

cgl5687600 1-44884150 (cancer vs cancer)

59280952 (cancer+normal vs 8

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- (normal vs normal) cgl204968 (cancer vs cancer) cg03611060 1-44884204

59281067 (cancer+normal vs 8 (cancer+normal vs cancer+normal) cancer+normal)

11- cg0493121

cgl5932284 (cancer vs cancer) 1-50885132 (cancer vs cancer)

126153561 6

cgl037589

11-518726 cg06367925 (cancer vs cancer) 1-50892511 (cancer vs cancer)

0

12- cg0402399

cg01428378 (cancer vs cancer) 1-50892794 (cancer vs cancer)

123259789 6

12- (cancer vs cancer) cg0313089

cg06880239 1-91550 (cancer vs cancer)

125670513 (cancer vs cancer) 1

(cancer vs cancer)

(cancer vs cancer)

12- 10- cgl833488 (cancer vs cancer) cg01063813 (normal vs normal)

57504948 102982492 1 (cancer vs cancer)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) 10- cgl 173072

cg23079808 (cancer vs cancer)

6493003 (cancer+normal vs 102985514 2

cancer+normal)

12- 10- cg0340414

cg07648238 (cancer vs cancer) (cancer vs cancer)

6493264 102986973 3

(cancer vs cancer)

12- lO- cgl990585

cg08740698 (cancer vs cancer) (cancer+normal vs

6493270 l l 8924620 6

cancer+normal)

12- (cancer vs cancer) 10- cg2480417

cgl0452531 (cancer vs cancer)

6493278 (cancer vs cancer) 124911034 2

(cancer vs cancer)

(cancer vs cancer)

12- 11- cg0233130 (cancer vs cancer) cgl4947547 (cancer+normal vs

6493495 67777823 3 (cancer+normal vs cancer+normal)

cancer+normal)

13- (cancer vs cancer) 11- cg0773030 (cancer vs cancer) cgl 1997708

114927854 (cancer vs cancer) 67777952 1 (cancer+normal vs (normal vs normal) cancer+normal)

(cancer+normal vs

cancer+normal)

13- 11- cg0919347

cgO 1440489 (cancer vs cancer) (cancer vs cancer)

41593385 86382900 9

(cancer vs cancer)

13- 11- cg0756009

cg02632314 (cancer+normal vs (cancer vs cancer) 41593416 86383182 6

cancer+normal)

14- (cancer vs cancer) 11- cgl339111

cgl2930714 (cancer vs cancer)

24835006 (cancer vs cancer) 86383236 6

14- (cancer vs cancer) 11- cgl488161

cgO 1174771 (cancer vs cancer)

32670315 (cancer vs cancer) 86383241 8

14- 12- cg0880039

cg23627301 (cancer vs cancer) (cancer vs cancer)

32673368 114200279 6

(cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer)

14- 12- cg0046760 (cancer vs cancer) cg02380334 (normal vs normal)

70038925 28128567 0 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (normal vs normal) 12- cgl727142

cgl4539393 (cancer vs cancer)

70038949 (cancer+normal vs 28128669 8

cancer+normal)

14- 12- cgl943572

cg20065569 (cancer vs cancer) (cancer vs cancer)

73958280 54387917 4

15- 13- cg2579452

cg03826564 (cancer vs cancer) (cancer vs cancer)

101629310 25321494 9

(cancer vs cancer)

15- 14- cgl720531

cgl0308906 (cancer vs cancer) (cancer+normal vs

89954991 57275386 6

cancer+normal)

15- (cancer vs cancer) 14- cg0082249

cgl8558647 (cancer vs cancer)

93198495 (cancer vs cancer) 57276490 5

(cancer vs cancer)

15- 15- cgl665697

cg21610221 (cancer+normal vs (cancer vs cancer)

93722499 37403242 9

cancer+normal)

(cancer vs cancer)

16- 15- cg2312550

cgl0060338 (cancer+normal vs (cancer vs cancer)

20774960 41198534 6

cancer+normal)

16- 16- cg0699900

cg04586407 (cancer vs cancer) (cancer vs cancer)

31008574 34258406 8

16- cg0991539

cg04374711 (cancer vs cancer) 17-2907895 (cancer vs cancer)

31008960 6

(cancer vs cancer)

16- (cancer vs cancer) cg0073977

cg05006755 17-2908023 (cancer vs cancer)

4233246 (cancer+normal vs 8

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16- 17- cg2154667

cg08554257 (cancer+normal vs (cancer+normal vs

50730737 46655387 1

cancer+normal) cancer+normal)

(cancer vs cancer)

17- cgl378977

16-744328 cg05542681 (cancer+normal vs (cancer vs cancer)

46655724 5

cancer+normal)

17- cg2592857

16-744861 cg03349020 (cancer vs cancer) (cancer vs cancer)

46692534 9

(cancer vs cancer) (cancer vs cancer)

17- cg2403062

16-744939 cg04005677 (cancer+normal vs (cancer+normal vs

59539397 2

cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal) 19- cgl519493

16-745663 cg02958327 (cancer vs cancer)

(cancer+normal vs 10405955 5

cancer+normal) (cancer vs cancer)

(cancer vs cancer) (normal vs normal) 19- cg2393658

16-745687 cg07482202 (cancer+normal vs

(cancer+normal vs 10406145 7

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- cg2707306 (cancer vs cancer) cg04313875 (normal vs normal) 19-2169160

1553202 6 (cancer vs cancer)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 2- cg0526820

cgl3180678 (cancer+normal vs

16256990 (cancer vs cancer) 118981748 3

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 2- cg0653049

cgl 1088422 (cancer+normal vs

42392697 (normal vs normal) 118981783 0

cancer+normal)

17- 2- cg0694645

cg20814095 (cancer vs cancer) (cancer vs cancer)

4802981 119606631 2

(cancer vs cancer)

(cancer vs cancer)

17- 2- cg0258363

cg00023001 (normal vs normal) (cancer vs cancer)

55938748 175192013 3

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

17- 2- cgl662510

cg22451358 (normal vs normal) (cancer+normal vs

55938871 175192189 9

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 2- cg2559252

cgl l963912 (cancer+normal vs (cancer+normal vs

72439044 175192312 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- (normal vs normal) 2- cgl715356

cg06615719 (cancer+normal vs

1455513 (cancer+normal vs 175199315 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- 2- cgl860978

cgl0565187 (normal vs normal) (cancer vs cancer)

1468943 175199349 3

(cancer+normal vs

cancer+normal)

19- 2- cgl381978

cg06508886 (cancer vs cancer) (cancer vs cancer)

1470292 175199464 7

19- 2- cg0271057

cg04314308 (cancer vs cancer) (cancer vs cancer)

19336150 223165320 1

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

19- 2- cgl406435

cg25814383 (normal vs normal) (cancer+normal vs

19336240 223165753 6

(cancer+normal vs cancer+normal) cancer+normal)

19- 2- cg2276443

cg23054321 (cancer vs cancer) (cancer vs cancer)

2289682 223168727 6

(cancer vs cancer)

(cancer vs cancer)

19- (cancer vs cancer) 2- cg0796399

cgl9250790 (cancer+normal vs

2614086 (cancer+normal vs 223170370 0

cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cg0956835

cg24139898 2-45228633 (cancer vs cancer)

35531817 (cancer+normal vs 5

cancer+normal)

19- (cancer vs cancer) cg0201957

cg21484586 2-45228640 (cancer vs cancer)

35531859 (cancer vs cancer) 4

19- cgl0369688 (cancer vs cancer) 2-45228716 cg2160860 (cancer vs cancer) 39898283 (normal vs normal) 0

(cancer+normal vs

cancer+normal)

19- 20- cg0983155

cg06663644 (cancer vs cancer) (cancer vs cancer)

40971204 60943241 3

(cancer vs cancer)

19- 21- cg2732515

cg08118159 (cancer vs cancer) (cancer+normal vs

41055208 38073307 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 21- cg0829708

cg23533683 (cancer+normal vs (cancer+normal vs

46144774 38073463 2

cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) 21- cg2731265

cg07925085 (cancer+normal vs

48824622 (cancer vs cancer) 38073517 2

cancer+normal)

19- 22- cg0838223

cg00438215 (cancer vs cancer) (cancer vs cancer)

7937107 19754251 5

2- 22- cg2150709

cg09759994 (cancer vs cancer) (cancer vs cancer)

113238376 19754448 5

2- 22- cg0499902

cgl0413944 (cancer vs cancer) (cancer vs cancer)

224702734 19754815 6

2- (cancer vs cancer) 3- cg2640547

cgl8998670 (cancer vs cancer)

58273552 (cancer vs cancer) 156324038 5

(cancer vs cancer)

20- 3- cgl070388

cg24467337 (cancer+normal vs (cancer vs cancer) 31262314 169384648 4

cancer+normal)

(cancer vs cancer)

3- 3- cg0284810

cgl9148281 (cancer vs cancer) (cancer+normal vs

111577973 170101493 6

cancer+normal)

3- 3- cg2636515

cg06828505 (cancer vs cancer) (cancer vs cancer)

111577981 176893572 2

3- (cancer vs cancer) 3- cgl870170

cg22481960 (cancer vs cancer)

13008800 (cancer vs cancer) 178560988 7

(cancer vs cancer) (cancer vs cancer)

3- cg2003836

cgl5038811 (cancer+normal vs (cancer+normal vs

28283857 180328345 8

cancer+normal) cancer+normal)

4- 3- cg2067538

cg07849581 (cancer vs cancer) (cancer vs cancer)

48272077 181421951 9

4- 3- cg0848894

cg06798642 (cancer vs cancer) (cancer vs cancer)

48272082 181422202 5

(cancer vs cancer) cgl243541

4-4854690 cgl7807131 (cancer vs cancer) (cancer+normal vs

186490344 5

cancer+normal)

4- 3- cg2679081

cg22054918 (cancer vs cancer) (cancer vs cancer)

81123613 187786456 8

5- cg0187086

cgl l571761 (cancer vs cancer) 3-48507087 (cancer vs cancer)

95298041 5

(cancer vs cancer)

5- cgl916233

cg20415170 (cancer vs cancer) 4-16084676 (cancer+normal vs

95298066 3

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cg0310184

cg04671145 4-16084682 (cancer+normal vs

157041096 (cancer vs cancer) 9

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

6- cg0781768

cg08501292 (normal vs normal) 4-16085401 (cancer+normal vs

25962987 6

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

6- (normal vs normal) 5- cg2620284

cg06153893 (cancer vs cancer)

25963109 (cancer+normal vs 153855353 7

cancer+normal) (cancer vs cancer)

6- (normal vs normal) 5- cgl542072

cg21844956 (cancer vs cancer)

25963442 (cancer+normal vs 172751061 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- cgl728839

cg23514619 (normal vs normal) 5-72715731 (cancer vs cancer)

43237330 7

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

6- cg0677967

cg20434586 (normal vs normal) 6-1378238 (cancer+normal vs

43237511 2

(cancer+normal vs cancer+normal) cancer+normal)

6- cg0897592

cg21427300 (cancer vs cancer) 6-1378677 (cancer vs cancer)

74233399 2

(cancer vs cancer)

6- (cancer vs cancer) cgl l84103

cg09681335 6-1380898 (cancer+normal vs

74233510 (cancer vs cancer) 8

cancer+normal)

6- cg0401828

cg21953307 (cancer vs cancer) 6-1383533 (cancer vs cancer)

74233640 8

(cancer vs cancer)

7- cg2232493

cg26269703 (cancer vs cancer) 6-1383631 (cancer+normal vs

149119681 4

cancer+normal)

7- cg0587270

cgl 1026333 (cancer vs cancer) 6-1383982 (cancer vs cancer)

150020269 6

7- (cancer vs cancer) cgl447099

cgl 1347411 6-50812995 (cancer vs cancer)

150020925 (cancer vs cancer) 8

7- cg0843457

cgl3534901 (cancer vs cancer) 6-99292438 (cancer vs cancer)

17339481 4

7- (cancer vs cancer) 7- cg0316741

cg06980547 (cancer vs cancer)

22894557 (cancer vs cancer) 113723093 3

8- (cancer vs cancer) 7- cg2105350

cg24115571 (cancer vs cancer)

104310713 (cancer vs cancer) 113723569 9

8- cg0352943

cg23685597 (cancer vs cancer) 7-27187502 (cancer vs cancer)

143556749 2

(cancer vs cancer)

8- (cancer vs cancer) cgl691378

cg01725531 7-27204005 (cancer+normal vs

23082789 (cancer vs cancer) 9

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) cg2518839

cg08305799 7-27204052 (cancer vs cancer)

30580804 (cancer+normal vs 5

cancer+normal)

8- (cancer vs cancer) cg0666927

cg20577468 7-27228627 (cancer vs cancer)

80803196 (normal vs normal) 6

(cancer vs cancer)

8- cgl799640

cg06107816 (cancer+normal vs 7-47611235 (cancer vs cancer)

80803365 1

cancer+normal)

9- 8- cg2638796

cgl4543508 (cancer vs cancer) (cancer vs cancer)

123631308 144503421 6

9- 8- cgl926237

cg03808351 (cancer vs cancer) (cancer vs cancer)

123631620 144503586 7

9- cgl583043

cgl3912930 (cancer vs cancer) 8-99952591 (cancer vs cancer)

34379890 1

Status - Hypo Status - Hypo

(normal vs normal)

(cancer vs cancer)

1- 1- cgl 125838

cg27508545 (cancer vs cancer) (cancer vs cancer)

10240017 117350694 1

(cancer+normal vs

cancer+normal)

1- cg23661000 (normal vs normal) 1-12304452 cg2372886 (cancer vs cancer) 10240025 (cancer vs cancer) 7

(cancer vs cancer)

(cancer+normal vs

cancer+normal)

1- 1- cg0947382

cg26110834 (cancer vs cancer) (cancer vs cancer)

213500126 175568216 6

(cancer vs cancer)

(cancer vs cancer) 1- cg2268496 (cancer vs cancer)

1-3128606 cg22031783

(cancer vs cancer) 183204789 9 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- (cancer vs cancer) 1- cgl442023 (cancer vs cancer) cg09506001

36559506 (cancer+normal vs 183204836 0 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) cgl463975

1-6390793 cg00081799 1-1913799 (cancer vs cancer)

(cancer vs cancer) 3

(cancer vs cancer)

(cancer vs cancer) 1- cgl714586

1-9448660 cgl2658495 (cancer vs cancer)

(cancer+normal vs 211918768 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- (cancer vs cancer) 1- cg0101287

cg01467532 (cancer+normal vs

115738883 (cancer+normal vs 244613363 9

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

cg0441000

10-405225 cg20595750 (cancer vs cancer) 1-844499 (cancer vs cancer)

3

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) lO- cgl 129844

10-661009 cgl9926144 (cancer vs cancer)

(cancer+normal vs l l 9749726 6

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) 10- cg2572483

cg23871994 (cancer+normal vs

113577434 (cancer+normal vs 123493091 7

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) 10- cgl919788

cg07737063 (cancer+normal vs

1486341 (cancer+normal vs 135246701 8

cancer+normal) cancer+normal)

12- (cancer vs cancer) 10- cg0339891

cg03061518 (cancer vs cancer)

123738291 (cancer vs cancer) 35080979 0

12- (cancer vs cancer) cg0649477

cgl7429587 11-1006303 (cancer vs cancer)

124905230 (cancer vs cancer) 5

(cancer vs cancer)

12- (cancer vs cancer) cg0295284

cg23617848 11-1669278 (cancer vs cancer)

131452297 (cancer+normal vs 9

cancer+normal)

12- 11- cg0960905

cgl 1136205 (cancer vs cancer) (cancer vs cancer)

133351421 65102891 1

(cancer vs cancer)

(cancer vs cancer)

12- (cancer vs cancer) 11- cg2673923

cg24211304 (cancer+normal vs

4596426 (cancer+normal vs 72724062 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 11- cgl098164

12-656703 cg03539204 (cancer vs cancer)

(cancer+normal vs 85989647 8

cancer+normal)

13- (normal vs normal) 12- cgl288301 (cancer vs cancer) cg26951340

111893537 (cancer vs cancer) 104855500 4 (cancer+normal vs (cancer vs cancer) cancer+normal)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) 12- cg2474114

cg06206670 (cancer vs cancer)

113436564 (cancer+normal vs 11286360 8

cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) 12- cgl686097

cgl4737571 (cancer vs cancer)

113436568 (cancer+normal vs 132643897 1

cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) 12- cgl419124

cg03010009 (cancer vs cancer)

80585265 (cancer+normal vs 21547892 4

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 12- cgl805980

cg03403507 (cancer vs cancer)

32798387 (cancer+normal vs 51347058 2

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 12- cg0442736

cg24812523 (cancer vs cancer)

32798762 (cancer+normal vs 51347099 0

cancer+normal)

14- (cancer vs cancer) 12- cg0583703

cgl8459806 (cancer vs cancer)

51293793 (cancer vs cancer) 63015414 6

14- 12- cg2718506

_C g04147497 (cancer vs cancer) (cancer vs cancer)

69052728 63195796 3

(cancer vs cancer)

14- (cancer vs cancer) 12- cgl734408

cg24158307 (cancer vs cancer)

95599667 (cancer+normal vs 93101181 0

cancer+normal)

15- (cancer vs cancer) 12- cg2595512

cgl3191951 (cancer vs cancer)

71685353 (cancer vs cancer) 94121046 6

(cancer vs cancer) (cancer vs cancer)

16- 13- cg0803441

_C g03494430 (cancer+normal vs (cancer+normal vs

2177269 114115128 3

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

16- 14- cgl358946

cg00900231 (cancer vs cancer) (cancer+normal vs

50897271 100920326 3

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16- 14- cgl946125

cg03346415 (cancer+normal vs (cancer+normal vs

69854895 74182387 2

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

16- 15- cgl000707

cg02619656 (cancer vs cancer) (cancer vs cancer)

72460083 101099492 5

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

16- 15- cg0817774

cg05347108 (cancer vs cancer) (cancer vs cancer)

72460114 73524906 3

(cancer+normal vs

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16- (cancer vs cancer) 15- cg0633233 (cancer vs cancer) cg00319595

75300861 (cancer+normal vs 73889528 9 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

16- 15- cg0843515

cg03551062 (cancer vs cancer) (cancer vs cancer)

88041289 73889561 7

(cancer+normal vs cancer+normal)

(cancer vs cancer)

16- cg0609320

cg02207944 (cancer+normal vs 16-1405095 (cancer vs cancer)

89603606 1

cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- 17- cg0000274

cg00145352 (cancer vs cancer) (cancer vs cancer)

2319906 57839538 9

(cancer+normal vs

cancer+normal)

17- (cancer vs cancer) 18- cg0718797

cg06405341 (cancer vs cancer)

63535223 (cancer vs cancer) 60481018 1

(cancer vs cancer)

17- (cancer vs cancer) cg2571845

cg00711291 19-1351766 (cancer vs cancer)

71345538 (cancer+normal vs 1

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) 19- cg2145337

cg07366188 (cancer+normal vs

76220929 (cancer+normal vs 36024253 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- (cancer vs cancer) cg2296162 (cancer vs cancer) cgl0070788 19-5789699

76220955 (cancer+normal vs 3 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 2- cgl577577

cgl2130672 (cancer vs cancer)

9151012 (cancer+normal vs 109559185 9

cancer+normal)

(normal vs normal)

(cancer vs cancer)

(cancer vs cancer)

18- 2- cgl 146714 (cancer vs cancer) cg22291942 (cancer vs cancer)

32398181 132348705 1 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

18- 2- cg0316741

cg03722909 (cancer vs cancer) (cancer vs cancer)

42324965 132348901 5

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

18- 2- cg2080794

cg07015525 (cancer vs cancer) (cancer vs cancer)

42325086 191540713 8

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer) cgl717430

18-686346 cg01037496 2-19427767 (cancer vs cancer)

(cancer+normal vs 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- (cancer vs cancer) 2- cg2612674 (cancer vs cancer) cg24300446

1255516 (cancer+normal vs 239970075 9 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

19- 2- cg0878154 (cancer vs cancer) cg02383626 (cancer vs cancer)

18455508 239970152 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cg2416681

cgl5080870 2-56067277 (cancer vs cancer)

47770746 (cancer+normal vs 4

cancer+normal)

₉ (cancer vs cancer)

z- cg2551813

cg22764497 (cancer vs cancer) 2-63274476 (cancer vs cancer)

236716219 2

(cancer+normal vs cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl896532

cg06694561 2-99735582 (cancer vs cancer)

236716285 (cancer+normal vs 2

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) 22- cg2421182

cg06747919 (cancer vs cancer)

236716372 (cancer+normal vs 30572326 6

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) 22- cg0340969

cg00746446 (cancer vs cancer)

23879137 (cancer+normal vs 38525530 9

cancer+normal)

2- (cancer vs cancer) 3- cgl 125644

cg09675853 (cancer vs cancer)

239306169 (cancer vs cancer) 121380233 5

(normal vs normal)

₉ (cancer vs cancer)

z- 3- cg0136483

cg06257052 (cancer vs cancer) (cancer vs cancer)

240117222 121380236 3

(cancer+normal vs

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- (cancer vs cancer) 3- cgl799797 (cancer vs cancer) cg20853370

240117640 (cancer+normal vs 124885459 6 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) 3- cg2164407

cg00073794 (cancer vs cancer)

30041338 (cancer+normal vs 139012477 7

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

3- cgl343122

2-3292757 cg03025986 (cancer vs cancer) (cancer+normal vs

139062594 6

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 3- cgl997428

2-3480658 cg05777919 (cancer vs cancer)

(cancer+normal vs 149510376 3

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) 3- cgl645030

cg04768463 (cancer vs cancer)

55174473 (cancer+normal vs 170626822 9

cancer+normal)

2- (cancer vs cancer) 3- cgl508440

cg00820405 (cancer vs cancer)

97213642 (cancer vs cancer) 178738564 5

20- (cancer vs cancer) 3- cg0250007

cg04316905 (cancer vs cancer)

5985495 (cancer vs cancer) 179263203 5

(normal vs normal)

(cancer vs cancer)

22- 3- cg2500818

cgl2894883 (cancer vs cancer) (cancer vs cancer)

22288473 182123703 2

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

22- (cancer vs cancer) 3- cg0956265

cg00489795 (cancer vs cancer) 24041104 (cancer+normal vs 185704206 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

22- (cancer vs cancer) 3- cg0257970 (cancer vs cancer) cg26799416

42611379 (cancer+normal vs 187960622 6 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

3- cg0442329

cgl2678686 (cancer vs cancer) (cancer vs cancer)

127327369 188479059 4

(cancer+normal vs cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) 4- cg0524854

cgl9272592 (cancer vs cancer)

129408521 (cancer+normal vs 110484104 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (cancer vs cancer) 4- cgl305665

cg03320743 (cancer+normal vs

147657586 (cancer+normal vs 141538969 3

cancer+normal) cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) cg2196211

cg20224111 4-2065749 (cancer vs cancer)

195616361 (cancer+normal vs 5

cancer+normal)

3- cgl750775

cgl5171154 (cancer vs cancer) 5-41275792 (cancer vs cancer)

30722557 1

(normal vs normal)

(cancer vs cancer)

4- 6- cgl362723

cg01578875 (cancer vs cancer) (cancer vs cancer)

146804010 135094957 4

(cancer+normal vs

cancer+normal)

4- (cancer vs cancer) 6- cg0476652

cg05701706 (cancer vs cancer)

147187180 (cancer vs cancer) 137144557 9

(normal vs normal)

(cancer vs cancer)

4- 6- cg2319282

cgl0569820 (cancer vs cancer) (cancer vs cancer)

24982540 142738443 4

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

4- (cancer vs cancer) 6- cg0224762

cg26784682 (cancer+normal vs

39064477 (cancer vs cancer) 157335170 5

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) 6- cg0343567

cg06612355 (cancer vs cancer)

102834858 (cancer+normal vs 158093883 7

cancer+normal)

5- (cancer vs cancer) cgO 186076

cgl 1830096 6-21781118 (cancer vs cancer)

140865433 (cancer vs cancer) 3

(normal vs normal)

(cancer vs cancer)

5- cg0337238

cg09645993 (cancer vs cancer) 6-25324431 (cancer vs cancer)

77289836 5

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

6- cg2423561

cg24574819 (cancer vs cancer) 6-31765083 (cancer vs cancer)

102224868 3

(cancer+normal vs

cancer+normal)

6- (cancer vs cancer) cg2182544

cgO 1080927 6-37606394 (cancer vs cancer)

125341187 (cancer vs cancer) 3

(cancer vs cancer)

6- (cancer vs cancer) cg0819382

cgl7596249 6-5412087 (cancer vs cancer)

157493773 (cancer+normal vs 1

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 7- cg0585511

cgl4549524 (cancer vs cancer)

24140822 (cancer+normal vs 101603335 6

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- (cancer vs cancer) 7- cg2661979 (cancer vs cancer) cg08908855

24140899 (cancer+normal vs 116779435 0 (cancer+normal vs cancer+normal) cancer+normal)

7- cg06010390 (normal vs normal) 7- cg0130748 (cancer vs cancer) 101849120 (cancer vs cancer) 129254604 3

(cancer vs cancer)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

7- (cancer vs cancer) 7- cg0842848

cg01234984 (cancer vs cancer)

101849473 (cancer+normal vs 140452281 6

cancer+normal)

(cancer vs cancer)

7- (cancer vs cancer) 7- cg2547717

cgl 1895696 (cancer vs cancer)

105283982 (cancer+normal vs 148481030 6

cancer+normal)

(cancer vs cancer)

7- 7- cgl670826

cgl7102674 (cancer+normal vs (cancer vs cancer)

140034703 157336976 4

cancer+normal)

(normal vs normal)

(cancer vs cancer) cgl372424 (cancer vs cancer)

7-2148642 cgl6329842 7-1615334

(cancer+normal vs 8 (cancer vs cancer) cancer+normal)

cgl925196

7-4746837 cg23587176 (cancer vs cancer) 7-1615406 (cancer vs cancer)

2

cgl845213

7-4747166 cgl0982851 (cancer vs cancer) 7-55209213 (cancer vs cancer)

1

(cancer vs cancer)

(cancer vs cancer) cg0125627

7-4747216 cg01275887 7-6208128 (cancer vs cancer)

(cancer+normal vs 8

cancer+normal)

(cancer vs cancer) cg0360398

7-4747261 cg07076109 7-87905335 (cancer vs cancer)

(cancer vs cancer) 7

(cancer vs cancer) cgO 164282

7-5535692 cg09286367 7-925664 (cancer vs cancer)

(cancer vs cancer) 7

7- cg2698833

cg03895496 (cancer vs cancer) 7-925778 (cancer vs cancer)

92398176 1

(cancer vs cancer)

8- (cancer vs cancer) cgl622258

cg02712949 7-926431 (cancer vs cancer)

87570714 (cancer+normal vs 1

cancer+normal)

(normal vs normal)

(cancer vs cancer)

cgl542894

8-9260354 cgl0359460 (cancer vs cancer) 8-1308280 (cancer vs cancer)

9

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 8- cg0223013

8-9537322 cgl0419849 (cancer vs cancer)

(cancer+normal vs 143424799 3

cancer+normal)

9- (cancer vs cancer) cg0422054

cgl4554539 8-48172992 (cancer vs cancer)

130854713 (cancer vs cancer) 1

(cancer vs cancer)

9- cg2343270

cgl4630692 (cancer vs cancer) 8-97278556 (cancer+normal vs

131145355 7

cancer+normal)

9- (cancer vs cancer) 9- cgl432257

_C gl4494733 (cancer vs cancer)

139410910 (cancer vs cancer) 135769402 0

(normal vs normal)

(cancer vs cancer)

9- 9- cgl387254

cgl4155501 (cancer vs cancer) (cancer vs cancer)

99264127 138661146 1

(cancer+normal vs

cancer+normal)

CESC (cancer vs (cancer+normal vs

cancer) cancer+normal)

Status - Hyper Status - Hyper 1- 1- cg2143612 (cancer+normal vs cg03892631 (cancer vs cancer)

163039184 164536135 0 cancer+normal)

1- 1- cg2070819 (cancer+normal vs cg21868774 (cancer vs cancer)

166134282 181062601 9 cancer+normal)

(cancer vs cancer)

1- cgl204968 (cancer vs cancer) cg02229993 (cancer vs cancer) 1-44884204

166134699 8 (cancer+normal vs cancer+normal)

1- 10- cg0588923 (cancer+normal vs cg24365464 (cancer vs cancer)

190448126 102983065 4 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- lO- cgl990585

cg04412646 (cancer+normal vs (cancer+normal vs

239549626 l l 8924620 6

cancer+normal) cancer+normal)

(cancer vs cancer)

1- cg2402080 (cancer+normal vs cg00371368 (cancer+normal vs 10-7448857

239550378 6 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 11- cg0773030

cg07808348 (cancer+normal vs (cancer+normal vs

240775075 67777952 1

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 12- cg2549610 (cancer+normal vs cg00155397 (cancer+normal vs

240775160 16190004 4 cancer+normal) cancer+normal)

(cancer vs cancer)

1- 12- cg0046760 (cancer vs cancer) cg24843474 (cancer vs cancer)

241520598 28128567 0 (cancer+normal vs cancer+normal)

(cancer vs cancer)

1- 14- cgl720531

cg00805867 (cancer vs cancer) (cancer+normal vs

66798063 57275386 6

cancer+normal)

1- 15- cgl279075 (cancer+normal vs cg04645342 (cancer vs cancer)

72748124 37369914 8 cancer+normal)

(cancer vs cancer)

1- 16- cg0809210 (cancer+normal vs cgl5090083 (cancer+normal vs

76540168 58535384 5 cancer+normal) cancer+normal)

10- 16- cgl 164077 (cancer+normal vs cg26926521 (cancer vs cancer)

112837240 58535416 3 cancer+normal)

12- 16- cg2710286 (cancer+normal vs cg26490054 (cancer vs cancer)

101604056 58535418 4 cancer+normal)

12- 16- cg0108443 (cancer+normal vs cg03239178 (cancer vs cancer)

103358881 58535556 5 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 16- cg0892714

cg07366196 (cancer+normal vs (cancer+normal vs

127865826 86321899 5

cancer+normal) cancer+normal)

(cancer vs cancer)

13- 17- cg2075879 (cancer+normal vs cgl5470836 (cancer+normal vs

100648306 21101734 1 cancer+normal) cancer+normal)

13- 17- cgl307754 (cancer+normal vs cg04633225 (cancer vs cancer)

28494161 41832873 5 cancer+normal)

(cancer vs cancer)

13- 17- cg0493046 (cancer+normal vs cg07213036 (cancer+normal vs

28542727 41832882 9 cancer+normal) cancer+normal)

(cancer vs cancer)

13- 17- cgl247328 (cancer+normal vs cg24321030 (cancer+normal vs

29292888 41832975 5 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- 17- cg2154667

cgl2775884 (cancer+normal vs (cancer+normal vs

29293133 46655387 1

cancer+normal) cancer+normal)

(cancer vs cancer)

13- 17- cg0460985 (cancer+normal vs cgl7128349 (cancer+normal vs

29293196 46655736 9 cancer+normal) cancer+normal)

13- cg20752818 (cancer vs cancer) 17- cg2298209 (cancer+normal vs 29293213 (cancer+normal vs 55339169 8 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- 17- cg2403062

cg21789898 (cancer+normal vs (cancer+normal vs

29293245 59539397 2

cancer+normal) cancer+normal)

(cancer vs cancer)

13- 19- cg0884533 (cancer+normal vs cgl8682423 (cancer+normal vs

29293279 10403403 3 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- 19- cg2393658

cg05034702 (cancer+normal vs (cancer+normal vs

61989701 10406145 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- 2- cg0526820

cg02246190 (cancer+normal vs (cancer+normal vs

61989859 118981748 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- 2- cg0653049

cgl3744663 (cancer+normal vs (cancer+normal vs

92050675 118981783 0

cancer+normal) cancer+normal)

(cancer vs cancer)

13- 2- cgl662510

cgl2678562 (cancer vs cancer) (cancer+normal vs

92050726 175192189 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- 2- cg2559252

cgl9162106 (cancer+normal vs (cancer+normal vs

92050991 175192312 6

cancer+normal) cancer+normal)

(cancer vs cancer)

14- 2- cgl715356

cgO 1762070 (cancer vs cancer) (cancer+normal vs

21101007 175199315 8

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- 2- cgl406435

cgl 1025763 (cancer+normal vs (cancer+normal vs

76819246 223165753 6

cancer+normal) cancer+normal)

(cancer vs cancer)

16- 2- cg0796399

cg09635053 (cancer vs cancer) (cancer+normal vs

1031944 223170370 0

cancer+normal)

16- 2- cgl798105 (cancer+normal vs cg04056343 (cancer vs cancer)

7137080 223176398 8 cancer+normal)

(cancer vs cancer)

16- cg0878175 (cancer+normal vs cg00253851 (cancer+normal vs 2-44172074

8223276 5 cancer+normal) cancer+normal)

17- cg0086953 (cancer+normal vs cg26297547 (cancer vs cancer) 2-58386677

58227714 3 cancer+normal)

(cancer vs cancer)

18- cgl648063 (cancer+normal vs cg05735765 (cancer+normal vs 2-65496336

32556655 4 cancer+normal) cancer+normal)

(cancer vs cancer)

18- 20- cg2744096 (cancer+normal vs cgl4309384 (cancer+normal vs

32557266 43954866 5 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

18- 21- cg2732515

cg24692068 (cancer+normal vs (cancer+normal vs

32557882 38073307 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

18- 21- cg0829708

cgl3550107 (cancer+normal vs (cancer+normal vs

32558066 38073463 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 21- cg2731265

cg06647417 (cancer+normal vs (cancer+normal vs

12076051 38073517 2

cancer+normal) cancer+normal)

19- 3- cgl202198 (cancer+normal vs cg05661139 (cancer vs cancer)

20011721 105831607 8 cancer+normal)

(cancer vs cancer)

19- 3- cgl675876 (cancer+normal vs cg23501467 (cancer+normal vs

20011770 113529180 4 cancer+normal) cancer+normal)

19- (cancer vs cancer) 3- cg0284810 (cancer vs cancer) cgl5420387

21579902 (cancer+normal vs 170101493 6 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

19- 3- cg2246344 (cancer+normal vs cgl7853707 (cancer+normal vs

23578260 170146757 4 cancer+normal) cancer+normal)

(cancer vs cancer)

19- 3- cgl l41759 (cancer+normal vs cgl9361542 (cancer+normal vs

23869985 170714485 8 cancer+normal) cancer+normal)

(cancer vs cancer)

19- 3- cg0849561 (cancer+normal vs cg21340148 (cancer+normal vs

2702986 171791143 7 cancer+normal) cancer+normal)

(cancer vs cancer)

19- 3- cg0317759 (cancer+normal vs cgl 3974464 (cancer+normal vs

49224165 171890144 3 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 3- cg2003836

cg02660823 (cancer+normal vs (cancer+normal vs

54410305 180328345 8

cancer+normal) cancer+normal)

(cancer vs cancer)

19- 3- cg0983005 (cancer+normal vs cgl2501868 (cancer+normal vs

57999026 180704359 9 cancer+normal) cancer+normal)

(cancer vs cancer)

19- 3- cgl911499 (cancer+normal vs cg08134106 (cancer+normal vs

57999036 181669865 9 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 3- cgl243541

cgl5745619 (cancer+normal vs (cancer+normal vs

57999041 186490344 5

cancer+normal) cancer+normal)

(cancer vs cancer)

19- 3- cg0713244 (cancer+normal vs cg09260640 (cancer+normal vs

57999177 189432110 9 cancer+normal) cancer+normal)

(cancer vs cancer)

- 3- cg0972915 (cancer+normal vs cg08535260 (cancer+normal vs

192960454 5 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) - cgl916233

cgl3854983 (cancer+normal vs 4-16084676 (cancer+normal vs

136875315 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) - cg0310184

cg23491599 (cancer+normal vs 4-16084682 (cancer+normal vs

155554688 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) - cg0781768

cgl 1706467 (cancer+normal vs 4-16085401 (cancer+normal vs

155554707 6

cancer+normal) cancer+normal)

(cancer vs cancer)

- cg0669701 (cancer+normal vs cgl8395675 (cancer+normal vs 5-109961

168149401 7 cancer+normal) cancer+normal)

2- cg2688351 (cancer+normal vs cg21364278 (cancer vs cancer) 5-17230962

168149519 7 cancer+normal)

(cancer vs cancer) (cancer vs cancer) cg0677967

cgl6921083 (cancer+normal vs 6-1378238 (cancer+normal vs

137483063 2

cancer+normal) cancer+normal)

(cancer vs cancer)

3- cgl l84103

cgl3217064 (cancer vs cancer) 6-1380898 (cancer+normal vs

137483099 8

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

J - cg2232493

cg05880330 (cancer+normal vs 6-1383631 (cancer+normal vs

137484517 4

cancer+normal) cancer+normal)

3- 6- cg2274562 (cancer+normal vs cgl7823751 (cancer vs cancer)

137487081 150276311 4 cancer+normal)

3- cg0195549 (cancer+normal vs cgl6434657 (cancer vs cancer) 6-49110730

137490228 2 cancer+normal)

(cancer vs cancer)

J - 7- cgl672056 (cancer+normal vs cgl5997484 (cancer+normal vs

62859461 129543162 4 cancer+normal) cancer+normal) (cancer vs cancer) (cancer vs cancer)

4- cgl691378

cgl2205729 (cancer+normal vs 7-27204005 (cancer+normal vs

46391694 9

cancer+normal) cancer+normal)

5- cg2082146 (cancer+normal vs cg24799909 (cancer vs cancer) 7-5666097

145724482 6 cancer+normal)

5- 9- cg2554204 (cancer+normal vs cg09088988 (cancer vs cancer)

146614298 124982087 1 cancer+normal)

(cancer vs cancer)

5- cg00524310 (cancer+normal vs Status - Hypo

160973736

cancer+normal)

5- cg0276947 (cancer+normal vs cg00261416 (cancer vs cancer) 1-17012728

39425545 7 cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- 1- cg2268496 (cancer vs cancer) cg08261837 (cancer+normal vs

57878745 183204789 9 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- 1- cgl442023 (cancer vs cancer) cg21617058 (cancer+normal vs

57878882 183204836 0 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

5- 1- cg0415869 (cancer+normal vs

_C g08445409 (cancer+normal vs

57878919 201523041 8 cancer+normal) cancer+normal)

(cancer vs cancer)

5- 1- cg2392643 (cancer+normal vs cg23123909 (cancer+normal vs

57878953 228890884 9 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- 1- cg0101287

cg07513791 (cancer+normal vs (cancer+normal vs

87437106 244613363 9

cancer+normal) cancer+normal)

(cancer vs cancer)

5- cg2513038 (cancer+normal vs cg21153697 (cancer+normal vs 1-27440721

87437337 1 cancer+normal) cancer+normal)

(cancer vs cancer)

5- cgl 139925 (cancer+normal vs cg26246127 (cancer+normal vs 1-47694517

87437400 4 cancer+normal) cancer+normal)

(cancer vs cancer)

5- cg2234080 (cancer+normal vs cgl9625088 (cancer+normal vs 1-61378118

87976156 7 cancer+normal) cancer+normal)

(cancer vs cancer)

5- 10- cgl443549 (cancer+normal vs cg24025896 (cancer+normal vs

87976294 133251574 8 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- 10- cgl919788

cg06523916 (cancer+normal vs (cancer+normal vs

87986642 135246701 8

cancer+normal) cancer+normal)

6- 11- cgl014884 (cancer+normal vs cgl6289417 (cancer vs cancer)

166400665 124767455 1 cancer+normal)

(cancer vs cancer)

6- 11- cg2673923

cgl4026561 (cancer vs cancer) (cancer+normal vs

166401464 72724062 3

cancer+normal)

(cancer vs cancer)

6- 11- cg2494134 (cancer+normal vs cgl 1400401 (cancer+normal vs

28762552 95093809 2 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 12- cgl288301

cg26616283 (cancer+normal vs (cancer+normal vs

11871535 104855500 4

cancer+normal) cancer+normal)

7- 12- cg2575216 (cancer+normal vs cg26748945 (cancer vs cancer)

11871690 111470657 3 cancer+normal)

(cancer vs cancer)

7- 12- cg0871073 (cancer+normal vs cgl2348203 (cancer+normal vs

11871837 111470672 9 cancer+normal) cancer+normal)

7- cgl5400117 (cancer vs cancer) 12- cgl 178716 (cancer+normal vs 11871843 113515332 0 cancer+normal)

7- 12- cg2766449 (cancer+normal vs cg01426853 (cancer vs cancer)

123673549 113515835 6 cancer+normal)

(cancer vs cancer)

cgl453360 (cancer+normal vs

7-1265325 cg21768566 (cancer+normal vs 12-3364419

5 cancer+normal) cancer+normal)

(cancer vs cancer)

7- 12- cgl 194906 (cancer+normal vs cgl6806794 (cancer+normal vs

152591581 49726761 0 cancer+normal) cancer+normal)

7- 12- cg0685068 (cancer+normal vs cg21633143 (cancer vs cancer)

154862021 56587526 7 cancer+normal)

7- 12- cg0597648 (cancer+normal vs cg09724492 (cancer vs cancer)

94537870 92524968 1 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 13- cg0803441

cg06164608 (cancer+normal vs (cancer+normal vs

12990437 114115128 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 14- cgl358946

cgl9024344 (cancer+normal vs (cancer+normal vs

12990622 100920326 3

cancer+normal) cancer+normal)

(cancer vs cancer)

8- 14- cg2184296 (cancer+normal vs cg26464821 (cancer+normal vs

12990744 53508673 7 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 14- cgl946125

cgl4904305 (cancer+normal vs (cancer+normal vs

12990898 74182387 2

cancer+normal) cancer+normal)

(cancer vs cancer)

8- 14- cgl647897 (cancer+normal vs cg24819686 (cancer+normal vs

12991143 77689345 7 cancer+normal) cancer+normal)

(cancer vs cancer)

8- 15- cgl383213 (cancer+normal vs cgl9040483 (cancer+normal vs

12991196 29442040 5 cancer+normal) cancer+normal)

(cancer vs cancer)

8- 15- cg2736532 (cancer+normal vs cg03304380 (cancer+normal vs

13134144 40727743 4 cancer+normal) cancer+normal)

(cancer vs cancer)

8- (normal vs normal) 15- cg2584053 (cancer+normal vs cg20536983

13134166 (cancer+normal vs 65032585 6 cancer+normal) cancer+normal)

15- cgl728624 (cancer+normal vs

Status - Hypo 69222592 4 cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

15- cg0633233 (cancer vs cancer)

1-1168432 cgl3924635 (cancer+normal vs

73889528 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

16- cg0046184 (cancer+normal vs

1-1168541 cg22220310 (cancer+normal vs

10523485 1 cancer+normal) cancer+normal)

(cancer vs cancer)

cg0919236 (cancer+normal vs

1-1168550 cgl4477263 (cancer+normal vs 16-1339782

9 cancer+normal) cancer+normal)

(cancer vs cancer)

1- cgl447012 (cancer+normal vs cg09045105 (cancer+normal vs 16-1587684

149871945 1 cancer+normal) cancer+normal)

1- cg0030558 (cancer+normal vs cgl3169641 (cancer vs cancer) 16-1610898

149872165 5 cancer+normal)

1- 16- cg0668594 (cancer+normal vs cg06941869 (cancer vs cancer)

168254154 19721858 9 cancer+normal)

1- 16- cg0890711 (cancer+normal vs cgl 1697440 (cancer vs cancer)

19280186 27482516 8 cancer+normal)

1- (cancer vs cancer) 16- cg2667883 (cancer+normal vs cgl2763668

19687257 (cancer+normal vs 29643261 5 cancer+normal) cancer+normal)

1- 16- cg0988935 (cancer+normal vs cg02709178 (cancer vs cancer)

202848987 56995813 0 cancer+normal)

(cancer vs cancer)

1- 17- cgl 179421 (cancer+normal vs cg08843283 (cancer+normal vs

32826969 35423816 5 cancer+normal) cancer+normal)

1- 17- cgl225979 (cancer+normal vs cgl6379513 (cancer vs cancer)

32827150 40442580 2 cancer+normal)

1- 17- cg0091387 (cancer+normal vs cg00326300 (cancer vs cancer)

33772032 76421538 9 cancer+normal)

10- cg0371997 (cancer+normal vs cg02571436 (cancer vs cancer) 17-7758102

77468337 8 cancer+normal)

(normal vs normal)

10- 17- cg0745069

cgl6260349 (cancer vs cancer) (cancer+normal vs

82221597 80804126 8

cancer+normal) cg0213524 (cancer+normal vs

11-460914 cg26889437 (cancer vs cancer) 17-998711

5 cancer+normal)

11- 19- cg0121544 (cancer+normal vs cgl3826564 (cancer vs cancer)

65306731 18980443 2 cancer+normal)

(cancer vs cancer)

11- 19- cg2145337

cg04007841 (cancer vs cancer) (cancer+normal vs

65307006 36024253 8

cancer+normal)

11- 19- cg0034618 (cancer+normal vs cg20892743 (cancer vs cancer)

68133159 50189880 0 cancer+normal)

(cancer vs cancer)

11- cg2296162 (cancer vs cancer) cg06989074 (cancer vs cancer) 19-5789699

68133177 3 (cancer+normal vs cancer+normal)

11- 2- cg2475051 (cancer+normal vs cg24728180 (cancer vs cancer)

68133235 127819455 3 cancer+normal)

(cancer vs cancer)

11- 2- cgl 146714 (cancer vs cancer) cgl6547529 (cancer vs cancer)

75140681 132348705 1 (cancer+normal vs cancer+normal)

12- _C g0804442 (cancer+normal vs cgl7382939 (cancer vs cancer) 2-20442131

110940444 7 cancer+normal)

14- 2- cg0293216 (cancer+normal vs cgl9544707 (cancer vs cancer)

103746266 233352951 7 cancer+normal)

(cancer vs cancer)

14- 2- cg2612674 (cancer vs cancer) cgl2853742 (cancer vs cancer)

24780890 239970075 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

16- 2- cg0878154 (cancer vs cancer) cg26442107 (cancer vs cancer)

11276460 239970152 9 (cancer+normal vs cancer+normal)

16- 2- cgl254721 (cancer+normal vs cg04519296 (cancer vs cancer)

2043015 240153820 8 cancer+normal)

16- 2- cg2687666 (cancer+normal vs cg06831064 (cancer vs cancer)

2229298 240302637 4 cancer+normal)

16- cgl599851 (cancer+normal vs cg07915849 (cancer vs cancer) 2-30334305

2391402 8 cancer+normal)

16- cgl439824 (cancer+normal vs cg03941745 (cancer vs cancer) 2-46385031

30442009 3 cancer+normal)

(normal vs normal)

16- cgl666725

cg00915858 (cancer vs cancer) 2-54697181 (cancer+normal vs

31154636 1

cancer+normal)

16- cg0189935 (cancer+normal vs cg00029825 (cancer vs cancer) 2-61918195

31500439 5 cancer+normal)

16- 20- cgl 157771 (cancer+normal vs cg03105756 (cancer vs cancer)

4589127 20258001 6 cancer+normal) (normal vs normal)

16- 20- cg0834075

cg06426253 (cancer vs cancer) (cancer+normal vs

67314073 30176106 5

cancer+normal)

17- 20- cgl l61781 (cancer+normal vs cg03964554 (cancer vs cancer)

59521084 50010224 6 cancer+normal)

(normal vs normal)

17- 22- cg0101021

cg02934718 (cancer vs cancer) (cancer+normal vs

59521299 17956453 1

cancer+normal)

17- 22- cg2407447 (cancer+normal vs cg06454901 (cancer vs cancer)

59521422 17956455 7 cancer+normal)

17- 22- cg0340890 (cancer+normal vs cgl4690510 (cancer vs cancer)

60757589 17956462 4 cancer+normal)

(cancer vs cancer)

17- 3- cgl799797 (cancer vs cancer) cg01943414 (cancer vs cancer)

60757632 124885459 6 (cancer+normal vs cancer+normal)

17- 3- cg2165086 (cancer+normal vs cg00280220 (cancer vs cancer)

61926910 127299468 1 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 3- cgl343122

cgl3332729 (cancer+normal vs (cancer+normal vs

61927036 139062594 6

cancer+normal) cancer+normal)

17- 3- cgl282966 (cancer+normal vs cgl7887478 (cancer vs cancer)

7486551 153840379 6 cancer+normal)

17- 3- cgl235419 (cancer+normal vs cg05086567 (cancer vs cancer)

7486615 171159987 2 cancer+normal)

(cancer vs cancer)

17- 3- cg0257970 (cancer vs cancer) cg23765707 (cancer vs cancer)

80551747 187960622 6 (cancer+normal vs cancer+normal)

18- 3- cg2720356 (cancer+normal vs cg03778258 (cancer vs cancer)

10590639 193629645 0 cancer+normal)

19- cg0046765 (cancer+normal vs cgl8154954 (cancer vs cancer) 3-50357644

39055500 2 cancer+normal)

(cancer vs cancer)

19- 4- cgl305665

cg26703956 (cancer vs cancer) (cancer+normal vs

39260304 141538969 3

cancer+normal)

19- 4- cg0828242 (cancer+normal vs cgl2258179 (cancer vs cancer)

49232187 155702411 8 cancer+normal)

19- 5- cg0705628 (cancer+normal vs cgl4116320 (cancer vs cancer)

49232824 122433740 5 cancer+normal)

(cancer vs cancer)

19- 5- cgl l67136 (cancer+normal vs cg23074703 (cancer+normal vs

50392917 148810177 3 cancer+normal) cancer+normal)

2- cgl404999 (cancer+normal vs cg27117491 (cancer vs cancer) 5-1514140

39186743 0 cancer+normal)

2- 6- cgl622686 (cancer+normal vs cg02826525 (cancer vs cancer)

39186885 110418140 6 cancer+normal)

(cancer vs cancer)

2- 6- cg0418342 (cancer+normal vs cg03690080 (cancer+normal vs

39188006 119221279 5 cancer+normal) cancer+normal)

(cancer vs cancer)

2- 6- cg0224762

cgl4877896 (cancer vs cancer) (cancer+normal vs

74743839 157335170 5

cancer+normal)

2- cgl813980 (cancer+normal vs cg04748828 (cancer vs cancer) 6-32151517

75186308 0 cancer+normal)

20- cg2582421 (cancer+normal vs cg00045515 (cancer vs cancer) 6-33040535

35723332 7 cancer+normal)

(cancer vs cancer)

20- 7- cg2661979 (cancer vs cancer) cgl9746719 (cancer vs cancer)

55904677 116779435 0 (cancer+normal vs cancer+normal) 20- 7- cgl281619 (cancer+normal vs cg23998200 (cancer vs cancer)

55904686 128577593 8 cancer+normal)

20- 7- cg2532695 (cancer+normal vs cg07347645 (cancer vs cancer)

58507171 148720088 2 cancer+normal)

20- 7- cg0646477 (cancer+normal vs cg23241473 (cancer vs cancer)

58507227 151145235 5 cancer+normal)

20- 7- cgl740369 (cancer+normal vs cg22214414 (cancer vs cancer)

58507232 152622135 9 cancer+normal)

(cancer vs cancer)

20- cg2266284 (cancer+normal vs cg21950459 (cancer+normal vs 7-2116648

58508076 4 cancer+normal) cancer+normal)

(cancer vs cancer)

20- cg2624416 (cancer+normal vs cgl2181372 (cancer+normal vs 8-12987449

58508123 4 cancer+normal) cancer+normal)

20- cgl524661 (cancer+normal vs cg20707333 (cancer vs cancer) 8-21905462

58514079 9 cancer+normal)

20- cg2718597 (cancer+normal vs cg00400263 (cancer vs cancer) 8-25095288

58514201 8 cancer+normal)

21- cg0289292 (cancer+normal vs cg03566291 (cancer vs cancer) 8-60032926

44831040 5 cancer+normal)

(cancer vs cancer)

21- cg2343270

cg04824511 (cancer vs cancer) 8-97278556 (cancer+normal vs

44831062 7

cancer+normal)

22- 9- cgl417801 (cancer+normal vs cg21918728 (cancer vs cancer)

29445711 112731026 3 cancer+normal)

(normal vs normal)

22- 9- cg0852985

cg09560452 (cancer vs cancer) (cancer+normal vs

29445903 139557920 2

cancer+normal)

22- cg05475277 (cancer vs cancer) (normal vs normal)

36902578

22- cg22959474 (cancer vs cancer) Status - Hyper

42395235

22- 1- cg0499121

cg23778094 (cancer vs cancer) (normal vs normal)

43254043 161089118 4

22- 1- cg0228896

cg00539564 (cancer vs cancer) (normal vs normal) 43254081 172413492 9

22- 1- cg0374824

cgl2649343 (cancer vs cancer) (normal vs normal)

47023005 172413542 3

3- 1- cg0695167

cg08889930 (cancer vs cancer) (normal vs normal)

127317798 221061837 7

3- 1- cg0341945

cg21111416 (cancer vs cancer) (normal vs normal)

148804720 228503882 8

3- cg0397675

cg04731810 (cancer vs cancer) 1-33330006 (normal vs normal)

148804727 4

3- cgl340024

cg04120413 (cancer vs cancer) 1-8480963 (normal vs normal)

148804743 9

(cancer vs cancer)

3- 10- cg0682206

cg02611507 (cancer+normal vs (normal vs normal)

148804746 31108101 7

cancer+normal)

3- 10- cg0513194

cg07275648 (cancer vs cancer) (normal vs normal)

148804790 53004308 0

3- 10- cg0127556

cg09352720 (cancer vs cancer) (normal vs normal)

148804818 79684776 6

3- cg2428464

cg00757822 (cancer vs cancer) 10-8125688 (normal vs normal)

155304922 0

3- 10- cgl212781

cgl8572353 (cancer vs cancer) (normal vs normal)

185191446 92079600 1

3- 10- cgl029997

cg25090325 (cancer vs cancer) (normal vs normal)

49755764 94455543 6

5- 10- cgl074130

cg04101060 (cancer vs cancer) (normal vs normal)

134364968 97175272 8 5- 11- cg0664617

cgl6313910 (cancer vs cancer) (normal vs normal)

157079312 116948652 4

5- 11- cg0040602

cg06348134 (cancer vs cancer) (normal vs normal)

42991495 120090023 3

5- cg0931566

cgl2866104 (cancer vs cancer) 11-2612781 (normal vs normal)

96042628 2

6- cg2169547

cg00340855 (cancer vs cancer) 11-2612825 (normal vs normal)

30458586 5

6- cgl 158594

cgl 1594821 (cancer vs cancer) 11-2774756 (normal vs normal)

30458601 2

6- 11- cg0924474

cg01673307 (cancer vs cancer) (normal vs normal)

32819911 63532530 8

6- 11- cgl576947

cg24111025 (cancer vs cancer) (normal vs normal)

32819921 63852954 2

6- 11- cgl658964

cgl4926196 (cancer vs cancer) (normal vs normal)

37616482 96518853 4

7- 12- cg0903897

cg00013374 (cancer vs cancer) (normal vs normal)

100730520 104868173 1

7- 12- cgl397762

cg02849937 (cancer vs cancer) (normal vs normal)

156432293 119715090 0

7- 12- cgl975545

cg00465958 (cancer vs cancer) (normal vs normal)

156432526 19284928 9

(cancer vs cancer)

8- 12- cg2147726

cgl0802543 (cancer+normal vs (normal vs normal)

143782585 22777430 2

cancer+normal)

8- 12- cg0873857

cg26794938 (cancer vs cancer) (normal vs normal)

27549068 32655192 1

8- 12- cg2087269

cgl0699291 (cancer vs cancer) (normal vs normal)

28325115 51381135 2

9- 12- cg2055760

cgl9461260 (cancer vs cancer) (normal vs normal)

100849700 68873953 3

9- 13- cg2133179

cgl3515842 (cancer vs cancer) (normal vs normal)

127215440 113653004 1

(cancer+normal vs 13- cg2144273

(normal vs normal) cancer+normal) 25754851 0

13- cgl866208

Status - Hyper (normal vs normal)

29057716 0

1- (cancer+normal vs 13- cg2351533

cg23992410 (normal vs normal)

214160848 cancer+normal) 45883505 0

(cancer vs cancer)

1- 13- cg2043398

cg04412646 (cancer+normal vs (normal vs normal)

239549626 49683801 9

cancer+normal)

(cancer vs cancer)

1- 13- cgl348718

cg00371368 (cancer+normal vs (normal vs normal)

239550378 78428203 3

cancer+normal)

(cancer vs cancer)

1- 14- cg0105242

cg07808348 (cancer+normal vs (normal vs normal)

240775075 105802918 8

cancer+normal)

(cancer vs cancer)

1- 14- cgl 180255

cg00155397 (cancer+normal vs (normal vs normal)

240775160 65203330 3

cancer+normal)

(cancer vs cancer)

1- 15- cg0226286

cgl5090083 (cancer+normal vs (normal vs normal)

76540168 101593693 6

cancer+normal)

1- (cancer+normal vs 15- cg0615822

cg24580071 (normal vs normal)

76620271 cancer+normal) 43662311 7

11- (cancer+normal vs 15- cgl564758

cgl5240568 (normal vs normal)

14996456 cancer+normal) 80872041 4

(cancer vs cancer)

12- 15- cg0504249

cg07366196 (cancer+normal vs (normal vs normal)

127865826 89899729 2

cancer+normal) (cancer vs cancer)

13- 15- cg2433451

cgl5470836 (cancer+nornial vs (normal vs normal)

100648306 94346887 2

cancer+normal)

13- (cancer+normal vs 16- cg0537149

cgl l l53912

28494497 (normal vs normal) cancer+normal) 10989530 8

(cancer vs cancer)

13- 16- cg2617818

cg07213036 (cancer+normal vs (normal vs normal)

28542727 67232921 4

cancer+normal)

(cancer vs cancer)

13- 16- cg2677492

cg24321030 (cancer+normal vs (normal vs normal)

29292888 67478355 7

cancer+normal)

(cancer vs cancer)

13- 16- cg0756361

cgl2775884 (cancer+normal vs (normal vs normal)

29293133 70794856 1

cancer+normal)

(cancer vs cancer)

13- cgl877119

cgl7128349 (cancer+normal vs 17-182656 (normal vs normal)

29293196 5

cancer+normal)

(cancer vs cancer)

13- 17- cg2264828

cg20752818 (cancer+normal vs (normal vs normal)

29293213 21454238 2

cancer+normal)

(cancer vs cancer)

13- cg21789898 cg2349984

(cancer+normal vs 17-2608793 (normal vs normal)

29293245 6

cancer+normal)

(cancer vs cancer)

13- 18- cg2756982

cgl 8682423 (cancer+normal vs (normal vs normal)

29293279 60984485 9

cancer+normal)

(cancer vs cancer)

13- 19- cg2144847

cg05034702 (cancer+normal vs (normal vs normal)

61989701 10407538 1

cancer+normal)

(cancer vs cancer)

13- 19- cg0202457

cg02246190 (cancer+normal vs (normal vs normal)

61989859 14313682 9

cancer+normal)

(cancer vs cancer)

13- 19- cg22 1433

cgl3744663 (cancer+normal vs (normal vs normal)

92050675 14376960 8

cancer+normal)

(cancer vs cancer)

13- 19- cg2674941

cgl9162106 (cancer+normal vs (normal vs normal)

92050991 46807272 4

cancer+normal)

(cancer vs cancer)

14- cgl499547

cgl 1025763 (cancer+normal vs 19-6534774 (normal vs normal)

76819246 5

cancer+normal)

(cancer vs cancer)

16- 2- cgl350011

cg00253851 (cancer+normal vs (normal vs normal)

8223276 216947149 J

cancer+normal)

16- (cancer+normal vs 2- cg0915732

cg08617528 (normal vs normal)

8223313 cancer+normal) 227850069 0

(normal vs normal)

17- 2- cg2592657

cg22968622 (cancer+normal vs (normal vs normal)

43663579 233995465 2

cancer+normal)

17- (cancer+normal vs cg0205908

cgl 1740099 2-27604131 (normal vs normal)

80279430 cancer+normal) 2

(cancer vs cancer)

18- cg0211694

cg05735765 (cancer+normal vs 2-69519143 (normal vs normal)

32556655 2

cancer+normal)

18- (cancer+normal vs 22- cg2146185

cg20923716 (normal vs normal)

32557027 cancer+normal) 39852666 6

(cancer vs cancer)

18- 3- cgl734291

cgl4309384 (cancer+normal vs (normal vs normal)

32557266 104556025 6

cancer+normal)

18- (cancer vs cancer) cg2177168

cg24692068 3-11036537 (normal vs normal)

32557882 (cancer+normal vs 2 cancer+normal)

18- (cancer+normal vs 3- cg0744371

cg07326648 (normal vs normal)

32558052 cancer+normal) 129383357 7

(cancer vs cancer)

18- 3- cg2535825

cgl3550107 (cancer+normal vs (normal vs normal)

32558066 137573683 0

cancer+normal)

(cancer vs cancer)

19- 3- cgl404727

cg06647417 (cancer+normal vs (normal vs normal)

12076051 184097168 1

cancer+normal)

(cancer vs cancer)

19- 3- cg0549185

cg23501467 (cancer+normal vs (normal vs normal)

20011770 186891900 8

cancer+normal)

(cancer vs cancer)

19- 4- cgl314956

cgl5420387 (cancer+normal vs (normal vs normal)

21579902 101238231 6

cancer+normal)

19- (cancer+normal vs cgl767961

cg26151087 4-74542972 (normal vs normal)

21579911 cancer+normal) 9

19- (cancer+normal vs 5- cgl760560

cg20103107 (normal vs normal)

23578063 cancer+normal) 102612899 4

(cancer vs cancer)

19- cg2692440

cgl7853707 (cancer+normal vs 5-1394484 (normal vs normal)

23578260 8

cancer+normal)

(cancer vs cancer)

19- cg2116334

cgl9361542 (cancer+normal vs 5-1394633 (normal vs normal)

23869985 7

cancer+normal)

(cancer vs cancer)

19- 5- cg2287702

cg21340148 (cancer+normal vs (normal vs normal)

2702986 143021669 4

cancer+normal)

19- (cancer+normal vs 5- cg0829563

cg03170611 (normal vs normal)

28284813 cancer+normal) 169532758 9

(cancer vs cancer)

19- cg0105836

cgl 3974464 (cancer+normal vs 5-24645487 (normal vs normal)

49224165 8

cancer+normal)

19- (cancer+normal vs cgl747278

cgl7428324 5-389355 (normal vs normal)

52531703 cancer+normal) 6

(cancer vs cancer)

19- cg0455177

cg02660823 (cancer+normal vs 5-393366 (normal vs normal)

54410305 6

cancer+normal)

(cancer vs cancer)

19- cg2247333

cgl2501868 (cancer+normal vs 5-54287462 (normal vs normal)

57999026 3

cancer+normal)

(cancer vs cancer)

19- cg0106171

cg08134106 (cancer+normal vs 5-64330880 (normal vs normal)

57999036 4

cancer+normal)

(cancer vs cancer)

19- cg0951020

cgl5745619 (cancer+normal vs 6-13014871 (normal vs normal)

57999041 2

cancer+normal)

19- (cancer+normal vs 6- cg2460148

cg07873812 (normal vs normal)

57999044 cancer+normal) 138814716 0

(cancer vs cancer)

19- 6- cg0428106

cg09260640 (cancer+normal vs (normal vs normal)

57999177 144508118 9

cancer+normal)

19- (cancer+normal vs 6- cgl521597

cg23015949 (normal vs normal)

57999447 cancer+normal) 167135152 8

19- (cancer+normal vs cgl570890

cg24863791 6-32487314 (normal vs normal)

58144608 cancer+normal) 9

(cancer vs cancer)

2- 7- cg2552754

cg08535260 (cancer+normal vs (normal vs normal)

127643971 100862300 7

cancer+normal)

2- (cancer vs cancer) 7- cg2457629

cgl3854983 (normal vs normal)

136875315 (cancer+normal vs 108137995 8 cancer+normal)

(cancer vs cancer)

2- 7- cg0272938

cg23491599 (cancer+normal vs

155554688 (normal vs normal)

130625473 3

cancer+normal)

(cancer vs cancer)

2- cg0622651

cgl 1706467 (cancer+normal vs 7-13072314

155554707 (normal vs normal)

6

cancer+normal)

(cancer vs cancer)

2- 7- cg0705587

cgl8395675 (cancer+normal vs

168149401 (normal vs normal)

143747474 9

cancer+normal)

(cancer vs cancer)

3- (normal vs normal)

7- cgl835663

cgl6921083 (cancer+normal vs

137483063 149734481 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

cg2519307

cgO5880330 (cancer+normal vs 7-1967621

137484517 J (normal vs normal) cancer+normal)

(normal vs normal)

3- cg0243378

cg01711746 (cancer+normal vs 7-39662467

138657291 (normal vs normal)

5

cancer+normal)

(normal vs normal)

3- cgl704823

cg07287724 (cancer+normal vs 8-28560467

138657429 (normal vs normal)

3

cancer+normal)

(normal vs normal)

3- cg2383029

cgl7769084 (cancer+normal vs 8-30300223

138657541 (normal vs normal)

0

cancer+normal)

(normal vs normal)

3- cg0821894

cgl 1023900 (cancer+normal vs 8-49731668

138657666 (normal vs normal)

4

cancer+normal)

(normal vs normal)

3- cg0289866

cg21530266 (cancer+normal vs 8-55368762

138657774 (normal vs normal)

5

cancer+normal)

(cancer vs cancer)

3- cg2262870

cgl5997484 (cancer+normal vs 8-61085389

62859461 (normal vs normal)

9

cancer+normal)

(cancer vs cancer)

4- cgl730854

cgl2205729 (cancer+normal vs 8-93150831

46391694 (normal vs normal)

5

cancer+normal)

4- (cancer+normal vs cgl524412

cg09615276 8-93978802

64767210 (normal vs normal) cancer+normal) 9

5- (cancer+normal vs 9- cgl465618

cg25194822

113699604 (normal vs normal) cancer+normal) 137701344 0

5- (cancer+normal vs

cg26413942

124081751 Status - Hypo

cancer+normal)

(cancer vs cancer)

5- 1- cg2306893

cg00524310 (cancer+normal vs

160973736 (normal vs normal)

112016586 9

cancer+normal)

5- (cancer+normal vs 1- cg2389485

cg21545840

168729558 (normal vs normal) cancer+normal) 112016615 4

5- (cancer+normal vs cg0413645

cg25770096 1-11413470

39425547 (normal vs normal) cancer+normal) 6

(cancer vs cancer)

5- 1- cgl937232

cg08261837 (cancer+normal vs

57878745 (normal vs normal)

149517402 7

cancer+normal)

5- (cancer+normal vs 1- cg0618854

cgl9416050

57878750 (normal vs normal) cancer+normal) 156863643 5

5- (cancer+normal vs cg0000283

cg22023952 1-44513358

57878853 (normal vs normal) cancer+normal) 7

(cancer vs cancer)

5- cgl571172

cg21617058 (cancer+normal vs 1-46632465

57878882 (normal vs normal)

7

cancer+normal)

5- cg08445409 (cancer vs cancer) 1-64942153 cg2622401 (normal vs normal) 57878919 (cancer+normal vs 8

cancer+normal)

(cancer vs cancer)

5- cgl924501

cg23123909 (cancer+normal vs 1-92414221 (normal vs normal)

57878953 1

cancer+normal)

(normal vs normal)

(cancer vs cancer)

5- cg0151551 (cancer vs cancer) cg07513791 (cancer+normal vs 1-92414295

87437106 5 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

5- 10- cg0659298

cg21153697 (cancer+normal vs (normal vs normal)

87437337 119443899 2

cancer+normal)

(cancer vs cancer)

5- 10- cg2137025

cg26246127 (cancer+normal vs (normal vs normal)

87437400 134150489 5

cancer+normal)

(cancer vs cancer)

5- 10- cgl455294

cgl9625088 (cancer+normal vs (normal vs normal)

87976156 28657329 7

cancer+normal)

(cancer vs cancer)

5- 10- cg0020113

cg24025896 (cancer+normal vs (normal vs normal)

87976294 35740216 3

cancer+normal)

5- (cancer+normal vs 10- cgl923050

cg02627887 (normal vs normal)

87976545 cancer+normal) 35926227 1

(cancer vs cancer)

5- 10- cgl794058

cg06523916 (cancer+normal vs (normal vs normal)

87986642 89292231 7

cancer+normal)

6- (cancer+normal vs 10- cgl406051

cg05861708 (normal vs normal)

166400871 cancer+normal) 95222867 9

(cancer vs cancer)

6- 11- cgl269568

cgl 1400401 (cancer+normal vs (normal vs normal)

28762552 33890131 5

cancer+normal)

6- (cancer+normal vs 11- cgl391230

cg20392842 (normal vs normal)

32909003 cancer+normal) 47416535 7

(cancer vs cancer)

7- 11- cg0142391

cg26616283 (cancer+normal vs (normal vs normal)

11871535 47885166 6

cancer+normal)

(cancer vs cancer)

7- 11- cgl979280

cgl2348203 (cancer+normal vs (normal vs normal)

11871837 65647270 2

cancer+normal)

(cancer vs cancer)

12- cg0791486

7-1265325 cg21768566 (cancer+normal vs (normal vs normal)

66583431 6

cancer+normal)

(cancer vs cancer)

7- 13- cg0630978

cgl6806794 (cancer+normal vs (normal vs normal)

152591581 40026426 8

cancer+normal)

(cancer vs cancer)

8- 14- cg2597438

cg06164608 (cancer+normal vs (normal vs normal)

12990437 105973925 0

cancer+normal)

(cancer vs cancer)

8- 14- cgl670126

cgl9024344 (cancer+normal vs (normal vs normal)

12990622 21024898 6

cancer+normal)

(cancer vs cancer)

8- 14- cg0479414

cg26464821 (cancer+normal vs (normal vs normal)

12990744 92325159 1

cancer+normal)

(cancer vs cancer)

8- 14- cgl418195

cgl4904305 (cancer+normal vs (normal vs normal)

12990898 93532563 6

cancer+normal)

(cancer vs cancer)

8- 15- cgl014620

cg24819686 (cancer+normal vs (normal vs normal)

12991143 27111435 3

cancer+normal)

8- cgl9040483 (cancer vs cancer) 15- cg0967245 (normal vs normal) 12991196 (cancer+normal vs 55665236 2

cancer+normal)

(cancer vs cancer)

8- 15- cgl331944

cg03304380 (cancer+normal vs (normal vs normal)

13134144 57592222 6

cancer+normal)

(cancer vs cancer)

8- (normal vs normal) 15- cg0015232

cg20536983 (normal vs normal)

13134166 (cancer+normal vs 65198005 2

cancer+normal)

15- cg0932510

Status - Hypo (normal vs normal)

65342522 1

(normal vs normal)

1- 16- cg0469588

cg21648376 (cancer+normal vs (normal vs normal)

116311395 20756332 2

cancer+normal)

(normal vs normal)

1- 16- cg0025337

cgl7903306 (cancer+normal vs (normal vs normal)

116311561 54404709 9

cancer+normal)

(cancer vs cancer)

16- cg0155441

1-1168432 cgl3924635 (cancer+normal vs (normal vs normal)

55359698 0

cancer+normal)

(cancer vs cancer)

16- cg0748491

1-1168541 cg22220310 (cancer+normal vs (normal vs normal)

84228377 0

cancer+normal)

(cancer vs cancer)

16- cg0878783

1-1168550 cgl4477263 (cancer+normal vs (normal vs normal)

86029554 7

cancer+normal)

(cancer vs cancer)

1- cgl l86919

cg09045105 (cancer+normal vs 17-2839187 (normal vs normal)

149871945 3

cancer+normal)

(normal vs normal)

1- (normal vs normal) 17- cgl727685

cgl4859874 (normal vs normal)

154238265 (cancer+normal vs 32964596 3

cancer+normal)

1- (cancer+normal vs 17- cgl479631

cg24039780 (normal vs normal)

164812337 cancer+normal) 34198571 8

(normal vs normal)

1- 17- cgl491628

cgl5109744 (cancer+normal vs (normal vs normal)

180917873 34345136 8

cancer+normal)

(cancer vs cancer)

1- 17- cgl043943

cgl2763668 (cancer+normal vs (normal vs normal)

19687257 34345172 1

cancer+normal)

1- (cancer+normal vs 17- cg0737583

cg23111655 (normal vs normal)

19764821 cancer+normal) 35717813 6

(cancer+normal vs 17- cg0239584 (normal vs normal)

1-2236443 cg20168901

cancer+normal) 43037309 6 (normal vs normal)

(cancer+normal vs 17- cgl943907

1-2236650 cg07425568 (normal vs normal) cancer+normal) 74557625 1

1- (cancer+normal vs 17- cg0998038

cg06721712 (normal vs normal)

243638141 cancer+normal) 76380922 4

(normal vs normal)

1- (cancer+normal vs 17- cg0745069

cg03848004 (cancer+normal vs

26107517 cancer+normal) 80804126 8

cancer+normal)

1- (cancer+normal vs cgl626847

cg26144567 17-8771003 (normal vs normal)

29446085 cancer+normal) 3

(cancer vs cancer)

1- cg0661376

cg08843283 (cancer+normal vs 17-8771055 (normal vs normal)

32826969 5

cancer+normal)

10- (cancer+normal vs 18- cgl617993

cgl5941413 (normal vs normal)

103420568 cancer+normal) 77277583 8

10- (normal vs normal) 19- cg0630560

cg09562683 (normal vs normal)

105210440 (cancer+normal vs 17634172 9 cancer+normal)

10- (cancer+normal vs cgl951931

cg20683445 19-2085301 (normal vs normal)

12853879 cancer+normal) 9

11- (cancer+normal vs 19- cg0270903

cgl 1609668 (normal vs normal)

117075078 cancer+normal) 33699683 2

11- (cancer+normal vs cgl890110

cg07592519 19-4916783 (normal vs normal)

2735101 cancer+normal) 4

11- (cancer+normal vs 2- cg2684280

cgl7485717 (normal vs normal)

33081126 cancer+normal) 202125212 2

(normal vs normal)

11- 2- cg0647850

cg05495611 (cancer+normal vs (normal vs normal)

44243314 240174613 4

cancer+normal)

(normal vs normal)

11- 2- cgl793988

cgl2710531 (cancer+normal vs (normal vs normal)

88032774 240174650 9

cancer+normal)

12- (cancer+normal vs 2- cgl402005

cg26415787 (normal vs normal)

133414334 cancer+normal) 240174659 2

(normal vs normal)

12- (cancer+normal vs cgl666725

cg01975858 2-54697181 (cancer+normal vs

15907517 cancer+normal) 1

cancer+normal)

12- (cancer+normal vs cgl592868

cg09192801 2-54823768 (normal vs normal)

77156412 cancer+normal) 0

(normal vs normal)

13- (cancer+normal vs 20- cg0834075

cg04656015 (cancer+normal vs

113407548 cancer+normal) 30176106 5

cancer+normal)

13- (cancer+normal vs 20- cgl585848

cg23167246 (normal vs normal) 114150035 cancer+normal) 56073589 3

(normal vs normal)

13- (cancer+normal vs 22- cg0101021

cgl2939777 (cancer+normal vs 114203831 cancer+normal) 17956453 1

cancer+normal)

13- (cancer+normal vs 22- cg0719723

cg03295274 (normal vs normal)

50190584 cancer+normal) 17956641 0

14- (cancer+normal vs 22- cgl228438

cg01358620 (normal vs normal)

31858202 cancer+normal) 35940438 2

(normal vs normal)

14- 22- cg0138395

cg00750630 (cancer+normal vs (normal vs normal)

51854261 42828447 5

cancer+normal)

15- (cancer+normal vs cg0264378

cg00232832 3-14853225 (normal vs normal)

30163660 cancer+normal) 2

(normal vs normal)

15- 3- cg0442561

cg20640374 (cancer+normal vs (normal vs normal)

31355304 183309985 7

cancer+normal)

(normal vs normal)

16- 3- cg2570265

cg07341220 (cancer+normal vs (normal vs normal)

1583899 192675515 1

cancer+normal)

(normal vs normal)

16- 3- cgl543165

cg00463982 (cancer+normal vs (normal vs normal)

1583984 194901357 9

cancer+normal)

16- (cancer+normal vs cg2381798

cg05110241 3-32993063 (normal vs normal)

68378359 cancer+normal) 1

16- (cancer+normal vs cg0152058

cg26832686 3-50280404 (normal vs normal)

69958189 cancer+normal) 6

16- (cancer+normal vs 4- cg2446753

cg01578632 (normal vs normal)

69958298 cancer+normal) 100244604 5

16- (cancer+normal vs cg0709429

cgl6589807 4-2748026 (normal vs normal)

75328793 cancer+normal) 8

16- (cancer+normal vs cg0152618

cg04340114 4-788117 (normal vs normal)

89468673 cancer+normal) 3

(normal vs normal)

17- 5- cg0040569

cg26177311 (cancer+normal vs (normal vs normal)

17449166 100239919 9

cancer+normal) 17- (cancer+normal vs 5- cg0597976

cgl7876831 (normal vs normal) 18918410 cancer+normal) 141395447 6

17- (cancer+normal vs 5- cg2218499

cg03025825 (normal vs normal)

1975245 cancer+normal) 142382188 0

17- (cancer+normal vs 5- cg0099725

cg24808754 (normal vs normal) 40851514 cancer+normal) 142444988 1

17- (cancer+normal vs 5- cgl 113909

cg08499158 (normal vs normal)

42289980 cancer+normal) 176294068 0

17- (cancer+normal vs cg0530504

cg03743861 5-40841315 (normal vs normal)

48263173 cancer+normal) 6

17- (cancer+normal vs cgl998505

cgl 1615029 5-56595244 (normal vs normal)

48263189 cancer+normal) 6

17- (cancer+normal vs cg0562555

cg25735490 5-6775922 (normal vs normal)

48263204 cancer+normal) 9

(cancer vs cancer)

17- cg0586841

cgl3332729 (cancer+normal vs 5-72701818 (normal vs normal)

61927036 0

cancer+normal)

(normal vs normal)

17- cgl515314

cg21000762 (cancer+normal vs 5-81470056 (normal vs normal)

78892850 1

cancer+normal)

17- (cancer+normal vs 6- cgl833468

cgl5331383 (normal vs normal)

78893363 cancer+normal) 132066129 1

17- (cancer+normal vs 6- cg0579785

cg01525498 (normal vs normal)

78893429 cancer+normal) 155739835 4

17- (cancer+normal vs 6- cg0891865

cgl5694704 (normal vs normal)

78894364 cancer+normal) 158447883 8

17- (cancer+normal vs 6- cgl748123

cg21818807 (normal vs normal)

78894477 cancer+normal) 160241360 5

17- (cancer+normal vs 6- cgO 162200

cgl 1935831 (normal vs normal)

80137075 cancer+normal) 170463397 6

(normal vs normal)

cg0920874

17-821621 cg02459042 (cancer+normal vs 6-29856353 (normal vs normal)

0

cancer+normal)

19- (cancer+normal vs cg0176196

cg07455685 6-52173014 (normal vs normal)

45150513 cancer+normal) 6

19- (cancer+normal vs 7- cgl888745

cg01518138 (normal vs normal)

45866874 cancer+normal) 115995934 8

(cancer vs cancer)

19- 7- cg0722325

cg23074703 (cancer+normal vs (normal vs normal)

50392917 150147988 3

cancer+normal)

2- (cancer+normal vs cgl380000

cg01942372 7-39629290 (normal vs normal)

109203501 cancer+normal) 5

2- (cancer+normal vs 8- cg0455492

cgl3482326 (normal vs normal)

118700475 cancer+normal) 105342491 9

(normal vs normal)

2- cg0357566

cgl5584989 (cancer+normal vs 8-41168186 (normal vs normal)

135203925 6

cancer+normal)

(normal vs normal)

2- cg0941038

cgl7032848 (cancer+normal vs 8-41168205 (normal vs normal)

238647755 9

cancer+normal)

2- (cancer+normal vs 9- cgl355837

cgl9851200 (normal vs normal)

242835165 cancer+normal) 126135610 1

(normal vs normal)

2- (cancer+normal vs 9- cg0852985

cg06360820 (cancer+normal vs

242988706 cancer+normal) 139557920 2

cancer+normal)

(cancer+normal vs LuCaG (cancer vs

2-3452563 cgl 1642891

cancer+normal) cancer)

(cancer+normal vs

2-3453196 cgl6793199 Status - Hyper

cancer+normal)

2- (cancer vs cancer) cgl652338

cg03690080 1-10856707 (cancer vs cancer)

39188006 (cancer+normal vs 0 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- (cancer+normal vs cg0090742

cg02822958 1-23668691

46747628 (normal vs normal) cancer+normal) 7

(cancer+normal vs cancer+normal)

(normal vs normal)

2- cgl9384241 cg0812307 (cancer vs cancer)

(cancer+normal vs 1-28764523

55393977 4 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

(normal vs normal)

20- cg0486597 (cancer vs cancer) cg09885502 (cancer+normal vs 1-40609565

57463991 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

20- cgl204968 (cancer vs cancer) cg21950459 (cancer+normal vs 1-44884204

58508076 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

20- cg0915258

cgl2181372 (cancer+normal vs 1-88928362

58508123 (cancer vs cancer)

2

cancer+normal)

3- (cancer+normal vs 10- cg2274829 (cancer vs cancer) cgl5067606

113458144 cancer+normal) 102489344 0 (cancer vs cancer)

3- (cancer+normal vs 10- cgl833488 (cancer vs cancer) cg20230305

123418791 cancer+normal) 102982492 1 (cancer vs cancer)

3- (cancer+normal vs 10- cg0284764

cg00893348

139353025 (cancer vs cancer) cancer+normal) 124910550 9

(normal vs normal)

3- 10- cg2266569

cgl5093769 (cancer+normal vs

139353058 (cancer vs cancer)

128593943 2

cancer+normal)

(cancer vs cancer)

10- cg2366577

cg02611507 (cancer+normal vs

148804746 (cancer vs cancer)

128593946 8

cancer+nomial)

4- (cancer+normal vs 10- cgO 1464067 cgl893272

24745718 (cancer vs cancer) cancer+normal) 128594141 6

5- (cancer+normal vs 10- cg0560877

cg06049297

65506308 (cancer vs cancer) cancer+normal) 128594144 7

(cancer vs cancer)

(normal vs normal)

6- cg2278318 (cancer vs cancer) cg21796935 (cancer+normal vs 10-8091753

170065938 0

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs cgl580386 (cancer vs cancer) cgl3809627 10-8092165

33228341 cancer+normal) 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

7- (cancer+normal vs cgl671089 (cancer vs cancer) cg21129976 10-8092264

100421502 cancer+normal) 4 (cancer+normal vs cancer+normal)

7- (cancer+normal vs 10- cgl658468

cgl 1872373

151833893 (cancer vs cancer) cancer+normal) 81206376 8

(cancer vs cancer)

(cancer+normal vs 11-

7-2144579 cgl008914

cgl8641463 (cancer+nomial vs cancer+nomial) 130030103 5

cancer+normal)

(cancer vs cancer)

7-4763182 (cancer+normal vs 11- cgl827062 (cancer vs cancer) cgl8733230

cancer+normal) 31831974 9 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer) (cancer vs cancer)

7-4806755 11- cg2684808 (cancer vs cancer) cg06114605

(cancer+normal vs 31832246 6 (cancer+normal vs cancer+normal) cancer+normal) (cancer+normal vs 11- cgl036418 (cancer vs cancer)

7-4806869 cg05102770

cancer+normal) 36615998 2 (cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer) 11- cg2167160

7-4806949 cg25330264 (cancer vs cancer)

(cancer+normal vs 36616015 7

cancer+normal)

(cancer+normal vs 11- cg2682132

7-4807062 cg06496454 (cancer vs cancer) cancer+normal) 36616048 7

(cancer+normal vs 11- cg2127299 (cancer vs cancer)

7-4807525 cgl7625535

cancer+normal) 57529255 6 (cancer vs cancer)

(cancer+normal vs 11- cgl083121 (cancer vs cancer)

7-5389516 cg20025824

cancer+normal) 57529419 2 (cancer vs cancer)

(cancer+normal vs 11- cgl921027 (cancer vs cancer)

7-811786 cg03184424

cancer+normal) 57529465 6 (cancer vs cancer)

(cancer+normal vs 11- cgl944699

7-837536 cg21113846 (cancer vs cancer) cancer+normal) 61739400 0

(cancer vs cancer)

(cancer vs cancer)

8- 11- cg0233130 (cancer vs cancer) cgl0802543 (cancer+normal vs

143782585 67777823 3 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

8- (cancer+normal vs 12- cg0046760 (cancer vs cancer) cg03408619

30300142 cancer+normal) 28128567 0 (cancer+normal vs cancer+normal)

8- (cancer+normal vs 12- cg2754995

cg06815361 (cancer vs cancer)

42659977 cancer+normal) 88974484 2

13- cg2593635

(normal vs normal) (cancer vs cancer)

114301996 8

13- cgl221219

Status - Hyper (cancer vs cancer)

114302021 8

1- 14- cg0812214

cgl0020333 (normal vs normal) (cancer vs cancer)

101704504 34420415 0

1- 15- cg0198720

cgl3110283 (normal vs normal) (cancer vs cancer)

233751191 40633194 2

10- 15- cg2270688 (cancer vs cancer) cg02595823 (normal vs normal)

73848915 67814880 3 (cancer vs cancer)

10- 15- cg2241005

cg24440658 (normal vs normal) (cancer vs cancer)

82295723 90456248 7

10- 15- cg2275593

cgl5642854 (normal vs normal) (cancer vs cancer)

82295864 98504668 2

10- 16- cgl 102777

cg09981929 (normal vs normal) (cancer vs cancer)

82296072 30817058 2

(cancer vs cancer)

11- 16- cgl l l8117 (cancer vs cancer) cg20815992 (normal vs normal)

10949337 55090946 1 (cancer+normal vs cancer+normal)

11- 16- cg2766518

cgl7320698 (normal vs normal) (cancer vs cancer)

30510489 70720149 1

(cancer vs cancer) le- cg0806829

11-316456 cg27331665 (normal vs normal) (cancer+normal vs

SS 842404 6

cancer+normal)

11- 16- cg0427608 (cancer vs cancer) cg04549333 (normal vs normal)

44325823 86478190 4 (cancer vs cancer)

(cancer vs cancer)

11- 16- cg0131390 (cancer vs cancer) cg04970352 (normal vs normal)

44327399 86609963 4 (cancer+normal vs cancer+normal)

12- 16- cg0363499

cg22741264 (normal vs normal) (cancer vs cancer)

115105519 90089283 7

12- 17- cg0819400

cg02506008 (normal vs normal) (cancer vs cancer)

115861520 25707428 9 (normal vs normal)

12- 17- cgl686482

cgl 1586448 (cancer+normal vs (cancer vs cancer)

123383399 37183552 5

cancer+normal)

12- 17- cg0244307

cg08724310 (normal vs normal) (cancer vs cancer)

25055304 37183683 2

12- 17- cgl543752

cgl5878670 (normal vs normal) (cancer vs cancer)

49485085 72427628 8

12- 17- cg0687345

cg24208826 (normal vs normal) (cancer vs cancer)

54389891 79370518 2

12- 17- cg2507266

cg22679316 (normal vs normal) (cancer vs cancer)

54396990 79533843 6

12- 18- cg0706449 (cancer vs cancer) cg03892356 (normal vs normal)

54420837 29304111 5 (cancer vs cancer)

12- 18- cgl778910

cgl 3826247 (normal vs normal) (cancer vs cancer)

54424203 45688478 2

12- 18- cg0636598

cg22466678 (normal vs normal) (cancer vs cancer)

89749033 72124683 4

13- 19- cg0619748 (cancer vs cancer) cg07800658 (normal vs normal)

111193758 13107252 2 (cancer vs cancer)

14- cg0809114 (cancer vs cancer) cgl3721907 (normal vs normal) 19-1676011

48148429 7 (cancer vs cancer)

15- cg2707306 (cancer vs cancer) cg20909380 (normal vs normal) 19-2169160

99987288 6 (cancer vs cancer)

16- 19- cg0689055

cg06834912 (normal vs normal) (cancer vs cancer)

86547203 44556485 3

(cancer vs cancer)

16- 2- cg2161604 (cancer vs cancer) cg00551679 (normal vs normal)

86547530 224467359 7 (cancer+normal vs cancer+normal)

17- 2- cg0605903

cg03184776 (normal vs normal) (cancer vs cancer)

41522069 236402544 2

(normal vs normal)

17- cg0147564

cg22968622 (cancer+normal vs 2-68073599 (cancer vs cancer)

43663579 9

cancer+normal)

17- cg0807959

cg24963001 (normal vs normal) 2-85999628 (cancer vs cancer)

46651952 6

17- 20- cgl460334

cgl3280788 (normal vs normal) (cancer vs cancer)

46652179 11871375 5

17- 20- cgl289464

cg05527785 (normal vs normal) (cancer vs cancer)

46656543 11871396 9

17- 20- cg2015977

cgl4285150 (normal vs normal) (cancer vs cancer)

46659019 11872206 5

17- 20- cg0582422

cgl4509967 (normal vs normal) (cancer vs cancer)

46679135 23618481 5

(cancer vs cancer)

17- 20- cg2134391 (cancer vs cancer) cg04573500 (normal vs normal)

55444427 46413743 9 (cancer+normal vs cancer+normal)

17- 20- cgl 197995

cg23398508 (normal vs normal) (cancer vs cancer)

70536199 46414900 9

17- 20- cg2208461 (cancer vs cancer) cgl5867652 (normal vs normal)

79011277 46414934 1 (cancer vs cancer)

18- 20- cgl975486

cg20976694 (normal vs normal) (cancer vs cancer)

55714052 46414999 1

18- 21- cg0557326

cgl9611392 (normal vs normal) (cancer vs cancer)

56888922 38071066 2

18- 21- cgl263095

cgl4963724 (normal vs normal) (cancer vs cancer)

72166303 38071688 3

21- cgl476920 (cancer vs cancer)

18-911318 cgl4479567 (normal vs normal)

38071807 7 (cancer vs cancer)

19- cg20725493 (normal vs normal) 21- cg2435860 (cancer vs cancer) 15740067 40984553 3 (cancer vs cancer)

2- 21- cg2026935 (cancer vs cancer) cgl4234152 (normal vs normal)

173601413 40984610 9 (cancer vs cancer)

2- 22- cg2391579

cg02466815 (normal vs normal) (cancer vs cancer)

177054573 41763255 2

2- 4- cg0031764

cg23719318 (normal vs normal) (cancer vs cancer)

20865651 125633640 8

2- 4- cgl308445

cg27243623 (normal vs normal) (cancer vs cancer)

228093069 128553917 8

2- cgl905006

cgl8781835 (normal vs normal) 4-77134471 (cancer vs cancer)

242892815 1

2- cg0459583

cg26682499 (normal vs normal) 4-85888263 (cancer vs cancer)

38342447 5

2- cg0264026

cgl6198930 (normal vs normal) 4-94749609 (cancer vs cancer)

54900343 0

2- 5- cg0005470 (cancer vs cancer) cg08379897 (normal vs normal)

85805621 135528543 2 (cancer vs cancer)

20- 5- cg2499648 (cancer vs cancer) cgl7361896 (normal vs normal)

3730680 174178256 2 (cancer vs cancer)

(cancer vs cancer)

21- cgl732949

cgl8681837 (normal vs normal) 5-65018961 (cancer+normal vs

15352213 4

cancer+normal)

(cancer vs cancer)

3- 6- cg0641339 (cancer vs cancer) cg03438417 (normal vs normal)

126007325 110736865 8 (cancer+normal vs cancer+normal)

(cancer vs cancer)

3- 6- cg0080407 (cancer vs cancer) cg02744524 (normal vs normal)

138655827 110736941 8 (cancer+normal vs cancer+normal)

3- 6- cg0716463

cg02704158 (normal vs normal) (cancer vs cancer)

138656042 110736958 9

(cancer vs cancer)

3- 6- cgl578589 (cancer vs cancer) cg05099537 (normal vs normal)

138656628 144608500 8 (cancer+normal vs cancer+normal)

(normal vs normal)

3- 6- cg0734618

cg01711746 (cancer+normal vs (cancer vs cancer)

138657291 149775621 7

cancer+normal)

(cancer vs cancer)

(normal vs normal) (cancer vs cancer)

3- 6- cg0591773

cg07287724 (cancer+normal vs (normal vs normal)

138657429 152623304 2

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(normal vs normal) (cancer vs cancer)

3- 6- cg0268245

cgl7769084 (cancer+normal vs (normal vs normal)

138657541 152623387 7

cancer+normal) (cancer+normal vs cancer+normal)

(normal vs normal)

3- cgl748969 (cancer vs cancer) cgl 1023900 (cancer+normal vs 6-50680997

138657666 5 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

(normal vs normal)

3- cg0369458 (cancer vs cancer) cg21530266 (cancer+normal vs 7-2271722

138657774 0 (cancer+normal vs cancer+normal)

cancer+normal)

3- cg0540686

cg06970190 (normal vs normal) 7-5467366 (cancer vs cancer)

138658243 8

3- cg2670292 (cancer vs cancer) cgl5665928 (normal vs normal) 8-21988147

138658345 9 (cancer vs cancer)

3- cg02019774 (normal vs normal) 8-21988173 cgl274825 (cancer vs cancer) 138658470 8

3- cg0490521

cg24625136 (normal vs normal) 8-22102083 (cancer vs cancer)

138658554 0

3- cgl656071

cg21575509 (normal vs normal) 8-93977794 (cancer vs cancer)

138658704 1

3- cgl044058

cg22132508 (normal vs normal) 8-93978221 (cancer vs cancer)

138658878 3

3- 9- cgl408506

cgl4504269 (normal vs normal) (cancer vs cancer)

138658941 107827215 0

(cancer vs cancer)

3- cgl456087 (cancer vs cancer) cgl5910502 (normal vs normal) 9-81871926

20085136 2 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(normal vs normal)

4-4871525 cg02680341 Status - Hypo

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

4- 1- cg2405836 (cancer vs cancer) cg25017774 (normal vs normal)

64223949 110923328 5 (cancer+normal vs

cancer+normal)

5- 1- cgl264350 (cancer vs cancer) cg22959827 (normal vs normal)

124461245 117151711 2 (cancer vs cancer)

(cancer vs cancer)

5- 1- cgl452095 (cancer vs cancer) cgl5646382 (normal vs normal)

140018709 154179856 7 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- cg0289676 (cancer vs cancer)

5-1594678 cg24960960 (cancer vs cancer)

154179996 8 (cancer+normal vs (normal vs normal)

cancer+normal)

(cancer vs cancer)

1- cg0034644

5-1594715 cg21931717 (cancer vs cancer) (cancer vs cancer)

156711439 6

(normal vs normal)

(cancer vs cancer)

6- 1- cg0471916 (cancer vs cancer) cgl9324940 (normal vs normal)

134213992 166806295 6 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

6- 1- cg2268496 (cancer vs cancer) cg03561416 (normal vs normal)

157254584 183204789 9 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

6- 1- cgl442023 (cancer vs cancer) cg05259303 (normal vs normal)

167508226 183204836 0 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

6- 1- cg0042608 (cancer vs cancer) cg20414186 (normal vs normal)

32064491 212671907 9 (cancer+normal vs

cancer+normal)

6- 1- cg0069039 (cancer vs cancer) cg03556669 (normal vs normal)

32064497 225697019 2 (cancer vs cancer)

6- 1- cg2742894

cg24882324 (normal vs normal) (cancer vs cancer)

32064508 232761750 8

(cancer vs cancer)

6- 1- cgl652481 (cancer vs cancer) cgl3400512 (normal vs normal)

32064578 236162295 8 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

6- cg2147425

cg25140213 (normal vs normal) 1-43399327 (cancer vs cancer)

32522683 7

(cancer+normal vs cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cg0056007 (cancer vs cancer) cgl2867728 1-61750543

32549283 (normal vs normal) 2 (cancer+normal vs cancer+normal)

6- cg2560684

cg06187770 (normal vs normal) 1-86052061 (cancer vs cancer)

85484863 2

(cancer vs cancer)

7- cg0644219 (cancer vs cancer) cg03964111 (normal vs normal) 1-92414344

150498493 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

7- cg0342144 (cancer vs cancer) cg24469729 (normal vs normal) 1-92414520

27160520 0 (cancer+normal vs cancer+normal)

7- cgl524529

cg20688917 (normal vs normal) 10-1120601 (cancer vs cancer)

27160674 2

7- 10- cg2629289

cgl 1267546 (normal vs normal) (cancer vs cancer)

27167828 112444795 5

(cancer vs cancer)

7- 10- cg0663361 (cancer vs cancer) cgl 1724970 (normal vs normal)

27182493 131592944 5 (cancer+normal vs cancer+normal)

(cancer vs cancer)

7- 11- cg0393302 (cancer vs cancer) cg23936031 (normal vs normal)

27183133 130089890 6 (cancer+normal vs cancer+normal)

7- 11- cgl433189

cg02248486 (normal vs normal) (cancer vs cancer)

27183196 61125360 9

7- 11- cgl903729

cgl9759481 (normal vs normal) (cancer vs cancer)

27183401 66515382 1

(cancer vs cancer)

7- 11- cg2730987 (cancer vs cancer) cgl7569124 (normal vs normal)

27183643 86224410 1 (cancer+normal vs cancer+normal)

7- 12- cgl581716 (cancer vs cancer) cg25307665 (normal vs normal)

27183694 132259591 3 (cancer vs cancer)

7- 12- cg2392599

cgl6764637 (normal vs normal) (cancer vs cancer)

27194731 94145366 4

7- 12- cg0635307

cg01363170 (normal vs normal) (cancer vs cancer)

27236674 99029458 5

(normal vs normal) (cancer vs cancer)

8- 13- cg0855718

cg08294772 (normal vs normal) (cancer vs cancer)

138135392 113420371 8

(cancer+normal vs cancer+normal)

(cancer vs cancer)

8- 13- cg0355054 (cancer vs cancer) cgO 1226742 (normal vs normal)

37699923 97787063 8 (cancer+normal vs cancer+normal)

(cancer vs cancer)

9- 13- cgl668919 (cancer vs cancer) cgl3843266 (normal vs normal)

38069959 98869844 3 (cancer+normal vs cancer+normal)

(cancer vs cancer)

9- 14- cgl430407 (cancer vs cancer) cgl3552373 (normal vs normal)

92291269 91691190 3 (cancer+normal vs cancer+normal)

(cancer vs cancer)

15- cg0633233

Status - Hypo (cancer vs cancer)

73889528 9

(cancer+normal vs cancer+normal)

(normal vs normal)

(normal vs normal) (cancer vs cancer)

1- 15- cg2238912

cg21648376 (cancer+normal vs (cancer vs cancer)

116311395 80217380 1

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(normal vs normal)

1- cg0079405 (cancer vs cancer) cgl7903306 (cancer+normal vs 16-2544909

116311561 5 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal) (cancer vs cancer)

1- (normal vs normal) cg2036418 (cancer vs cancer) cgl4859874 16-3139060

154238265 (cancer+normal vs 7 (cancer+normal vs cancer+normal) cancer+normal)

1- 17- cgl441939 (cancer vs cancer) cg21539842 (normal vs normal)

162641005 79953059 3 (cancer vs cancer)

(normal vs normal)

(cancer vs cancer)

1- (cancer vs cancer) 17- cg0398971

cg25214966 (cancer+normal vs

172113756 (cancer+normal vs 80970799 1

cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

1- 17- cgl 182456 (cancer vs cancer) cgl5109744 (cancer+normal vs

180917873 80970825 4 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

1- cg0186236

cgl2483005 (normal vs normal) 17-8928028 (cancer+normal vs

23474871 3

cancer+normal)

1- 19- cg0163228

cg03396152 (normal vs normal) (cancer vs cancer)

236147721 12880789 8

(cancer vs cancer)

1- cgl815641 (cancer vs cancer) cgl5718528 (normal vs normal) 19-4099405

244327251 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

1- cg2296162 (cancer vs cancer) cg09899564 (normal vs normal) 19-5789699

45103967 3 (cancer+normal vs cancer+normal)

1- 2- cgl 122319

cgl0220544 (normal vs normal) (cancer vs cancer)

60171660 105857809 6

(normal vs normal)

10- 2- cg0951033

cg09562683 (cancer+normal vs (cancer vs cancer)

105210440 105858013 9

cancer+normal)

(cancer vs cancer)

10- 2- cgl 146714 (cancer vs cancer) cg02257172 (normal vs normal)

13380770 132348705 1 (cancer+normal vs cancer+normal)

10- cg0952055 (cancer vs cancer) cg23443098 (normal vs normal) 2-15830021

13987636 4 (cancer vs cancer)

10- 2- cg0586129

cgl0431652 (normal vs normal) (cancer vs cancer)

31901490 207987538 1

(normal vs normal) (cancer vs cancer)

10- 2- cg2727394

cgl3654884 (normal vs normal) (cancer vs cancer)

94594240 232113244 6

(cancer+normal vs cancer+normal)

(cancer vs cancer)

10- 2- cg0835483 (cancer vs cancer) cg03122427 (normal vs normal)

97552565 234373030 5 (cancer+normal vs cancer+normal)

11- 2- cgl671986 (cancer vs cancer) cgl4816825 (normal vs normal)

12128203 234394478 5 (cancer vs cancer) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(normal vs normal)

11- 2- cgl721230 (cancer vs cancer) cg05495611 (cancer+normal vs

44243314 234394541 4 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

11- 2- cg2592316 (cancer vs cancer) cgl9145320 (normal vs normal)

75130069 234394645 2 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(normal vs normal)

11- 2- cgO 120601 (cancer vs cancer) cgl2710531 (cancer+normal vs

88032774 236672749 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

12- 2- cg2612674 (cancer vs cancer) cgl9641325 (normal vs normal)

116864616 239970075 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

12- 2- cg0878154 (cancer vs cancer) cg06225767 (normal vs normal)

11912232 239970152 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

12- cgl328658

cg07419011 (normal vs normal) 2-37883934 (cancer+normal vs

120688060 2

cancer+normal)

(cancer vs cancer)

12- cgl280410 (cancer vs cancer) cgl 1311053 (normal vs normal) 2-45557351

124912049 4 (cancer+normal vs cancer+normal)

12- cgl340917 (normal vs normal) cgl5026265 (normal vs normal) 2-61352525

28283812 4 (cancer vs cancer)

(cancer vs cancer)

12- 3- cgl799797 (cancer vs cancer) cg07303577 (normal vs normal)

3280014 124885459 6 (cancer+normal vs cancer+normal)

(cancer vs cancer)

12- 3- cg2576941

cgl2058490 (normal vs normal) (cancer+normal vs

9268379 132077190 2

cancer+normal)

(cancer vs cancer)

13- 3- cg0257970 (cancer vs cancer) cg26081974 (normal vs normal)

114065897 187960622 6 (cancer+normal vs cancer+normal)

(cancer vs cancer)

13- cgl549138 (cancer vs cancer) cgl9429300 (normal vs normal) 3-72537392

41114929 5 (cancer+normal vs cancer+normal)

14- 4- cgl534539

cgl 1835955 (normal vs normal) (cancer vs cancer)

40142517 113210708 3

(normal vs normal)

14- 4- cg2005411

cg00750630 (cancer+normal vs (cancer vs cancer)

51854261 140829046 1

cancer+normal)

(cancer vs cancer)

14- 5- cgl646512 (cancer vs cancer) cg02270243 (normal vs normal)

54815802 131408149 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

14- 5- cg0208481 (cancer vs cancer) cg02069592 (normal vs normal)

59198210 141722174 4 (cancer+normal vs cancer+normal)

14- 5- cg2319477 (cancer vs cancer) cgl4412134 (normal vs normal)

64912417 143026910 6 (cancer vs cancer) (cancer+normal vs cancer+normal)

14- 5- cg2478744

cgl8459040 (normal vs normal) (cancer vs cancer)

75478802 147781634 3

(cancer vs cancer)

15- cg0216515 (cancer vs cancer) cg03147324 (normal vs normal) 5-1546960

29928082 1 (cancer+normal vs cancer+normal)

(normal vs normal)

15- cg0247554 (cancer vs cancer) cg20640374 (cancer+normal vs 5-1596053

31355304 7 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

15- 6- cgl796985

cg24957518 (normal vs normal) (cancer+normal vs

31355362 108615613 3

cancer+normal)

15- 6- cgl087281

cgl4161369 (normal vs normal) (cancer vs cancer)

33143407 136436154 5

(cancer vs cancer)

15- 6- cg0861227 (cancer vs cancer) cg08872353 (normal vs normal)

68719924 143575123 1 (cancer+normal vs cancer+normal)

(cancer vs cancer)

15- 6- cgl l41252 (cancer vs cancer) cgl2737588 (normal vs normal)

70546706 170047483 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

16- cg0707727 (cancer vs cancer) cg08194933 (normal vs normal) 6-25726912

11271052 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(normal vs normal)

16- cgl405933 (cancer vs cancer) cg07341220 (cancer+normal vs 6-28875356

1583899 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(normal vs normal)

16- cg0827918 (cancer vs cancer) cg00463982 (cancer+normal vs 6-28875370

1583984 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

16- cgl000697 (cancer vs cancer) cgl0225951 (normal vs normal) 6-30900678

89647782 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(normal vs normal)

17- cg2164508 (cancer vs cancer) cg26177311 (cancer+normal vs 6-39072458

17449166 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

17- cg0355801 (cancer vs cancer) cg20695611 (normal vs normal) 6-46890220

35853648 0 (cancer+normal vs cancer+normal)

17- cg2051098

cg02225720 (normal vs normal) 6-88851522 (cancer vs cancer)

3623472 8

17- 7- cg2693269 (cancer vs cancer) cg00863893 (normal vs normal)

76876239 105254235 0 (cancer vs cancer)

(cancer vs cancer)

(normal vs normal)

17- 7- cg2661979 (cancer vs cancer) cg21000762 (cancer+normal vs

78892850 116779435 0 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(normal vs normal)

7- cg0828146 (cancer vs cancer)

17-821621 cg02459042 (cancer+normal vs

128767280 9 (cancer+normal vs cancer+normal)

cancer+normal)

18- cg26367197 (normal vs normal) 7- cg0433475 (cancer vs cancer) 76307273 129778936 1 (cancer vs cancer)

(cancer+normal vs cancer+normal)

19- 7- cg2737761

cgl0591771 (normal vs normal) (cancer vs cancer)

3671118 143204891 0

2- cgl372424 (cancer vs cancer) cg02049833 (normal vs normal) 7-1615334

101434611 8 (cancer vs cancer)

(cancer vs cancer)

2- cgl790762 (cancer vs cancer) cg01741688 (normal vs normal) 7-2473529

109781768 8 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(normal vs normal)

2- cgl825948 (cancer vs cancer) cgl5584989 (cancer+normal vs 7-2473859

135203925 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

2- cg0831040 (cancer vs cancer) cg23482132 (normal vs normal) 7-5262452

153415027 0 (cancer+normal vs cancer+normal)

(cancer vs cancer)

2- cg2009945

cgl 1375458 (normal vs normal) 7-5272275 (cancer+normal vs

177003996 8

cancer+normal)

(normal vs normal)

2- cg0216672

cgl8516557 (normal vs normal) 7-77126994 (cancer vs cancer)

177004015 5

(cancer vs cancer)

(cancer vs cancer)

2- cgl942010 (cancer vs cancer) cg21818470 (normal vs normal) 7-98996656

177004975 1 (cancer+normal vs cancer+normal)

2- cg0306884

cg25424742 (normal vs normal) 8-12985953 (cancer vs cancer)

238292904 3

(normal vs normal)

2- 8- cgl465022

cgl7032848 (cancer+normal vs (cancer vs cancer)

238647755 144573510 8

cancer+normal)

(cancer vs cancer)

2- cg2633366

cgl3184448 (normal vs normal) 8-28625366 (cancer+normal vs

238647857 0

cancer+normal)

2- cg0608341

cg04011338 (normal vs normal) 8-71228213 (cancer vs cancer)

238777587 2

(cancer vs cancer)

2- cg2118528 (cancer vs cancer) cgl0160614 (normal vs normal) 9-14690531

239544973 3 (cancer+normal vs cancer+normal)

(normal vs normal)

2- (cancer vs cancer) cgl374685

cgl9449565 9-34370894 (cancer vs cancer)

240230892 (cancer+normal vs 4

cancer+normal)

2- cg2117434 (cancer vs cancer) cg07506560 (normal vs normal) 9-99450036

240697449 4 (cancer vs cancer)

2- LuPaACaG (cancer vs

cg02053818 (normal vs normal)

38397399 cancer)

(normal vs normal)

2- cgl9384241 (cancer+normal vs Status - Hyper

55393977

cancer+normal)

cgl378825 (cancer vs cancer)

2-864706 cg08242232 (normal vs normal) 1-13840381

8 (cancer vs cancer)

(normal vs normal)

20- cg2307112 (cancer vs cancer) cg09885502 (cancer+normal vs 1-13840480

57463991 0 (cancer vs cancer) cancer+normal)

21- cg2653618 (cancer vs cancer) cg04233620 (normal vs normal) 1-13840494

46629219 9 (cancer vs cancer) (normal vs normal)

3- (cancer vs cancer) cgOl 14493 (cancer vs cancer) cg23733260 1-13840612

107381326 (cancer+normal vs 3 (cancer vs cancer) cancer+normal)

3- 1- cg2575519

cg00574513 (normal vs normal) (cancer vs cancer)

123417080 167013332 1

(normal vs normal)

3- 1- cg0489464

cgl5093769 (cancer+normal vs (cancer vs cancer)

139353058 178062853 2

cancer+normal)

(cancer vs cancer)

(normal vs normal)

4- 1- cg0015385 (cancer vs cancer) cgl3042918 (cancer+normal vs

119948542 182584341 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cg0871809

cg08936645 (normal vs normal) 1-23668792 (normal vs normal)

37910273 7

(cancer+normal vs cancer+normal)

5- 10- cg0449285 (cancer vs cancer) cg02484352 (normal vs normal)

131599890 133558786 8 (cancer vs cancer)

5- 10- cg2346070 (cancer vs cancer) cgl5141378 (normal vs normal)

135315386 133558971 7 (cancer vs cancer)

(cancer vs cancer)

5- cgl807262 (cancer vs cancer) cgl5540341 (normal vs normal) 10-8092036

15595186 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

5- cg0572151 (cancer vs cancer) cgl6525277 (normal vs normal) 10-8095288

171190008 5 (cancer+normal vs cancer+normal)

5- cg0972801 (cancer vs cancer) cg21204530 (normal vs normal) 10-8096305

172306136 2 (cancer vs cancer)

(normal vs normal)

5- cg2464727 (cancer vs cancer) cgl 1190987 (cancer+normal vs 10-8096311

64334489 6 (cancer vs cancer) cancer+normal)

(normal vs normal) (cancer vs cancer)

6- (cancer vs cancer) cgl518755 (cancer vs cancer) cg08061598 10-8096370

112081538 (cancer+normal vs 0 (cancer+normal vs cancer+normal) cancer+normal)

6- cgl585222

cgl6640450 (normal vs normal) 10-8096372 (cancer vs cancer)

148823251 3

(normal vs normal)

6- cgl989474

cg21796935 (cancer+normal vs 10-8096386 (cancer vs cancer)

170065938 7

cancer+normal)

6- cg0886060

_C g04941418 (normal vs normal) 10-8374293 (cancer vs cancer)

34493129 7

11- cgl077710

6-3760116 cg00380780 (normal vs normal) (cancer vs cancer)

113345325 3

(normal vs normal) (cancer vs cancer)

6- 11- cg0064847

cg00593404 (cancer+normal vs (cancer+normal vs

52377740 123525237 6

cancer+normal) cancer+normal)

7- 11- cg0651748

cg02561103 (normal vs normal) (cancer vs cancer)

115862891 22359333 9

7- 11- cgl277847

cg23590389 (normal vs normal) (cancer vs cancer)

157102769 22359345 6

(cancer vs cancer)

7- cg0247165 (cancer vs cancer) cgl4241836 (normal vs normal) 11-279950

48124921 8 (cancer+normal vs cancer+normal)

7- 11- cgl682238

cgl6182302 (normal vs normal) (cancer vs cancer)

55553545 31831591 7 (cancer vs cancer)

7- 11- cg0584003 (cancer vs cancer) cgl6212453 (normal vs normal)

73264533 31832353 1 (cancer+normal vs cancer+normal)

7- 12- cgl 114688

cgl5798862 (normal vs normal) (cancer vs cancer)

76129360 107487800 4

7- 12- cgl934637

cg22709100 (normal vs normal) (cancer vs cancer)

91322751 115120789 1

8- 12- cg2763031 (cancer vs cancer) cgl0941185 (normal vs normal)

12988516 115120847 1 (cancer vs cancer)

12- cgl971303 (cancer vs cancer)

8-1460569 cgl5938529 (normal vs normal)

115121016 8 (cancer vs cancer)

8- 12- cgl930361

cg07298985 (normal vs normal) (cancer vs cancer)

22133076 115121047 9

CHOL (cancer vs 12- cgl033002

(cancer vs cancer) cancer) 115121215 4

12- cgl857577

Status - Hyper (cancer vs cancer)

115121307 0

1- 12- cgl253005

cg02080641 (cancer vs cancer) (cancer vs cancer)

100111949 115121354 0

1- 12- cg2152000

cgl6251079 (cancer vs cancer) (cancer vs cancer)

113497932 118814505 2

1- 12- cgl067565

cg07423363 (cancer vs cancer) (cancer vs cancer)

113497999 19283425 9

1- cg2041622

cgl2551029 (cancer vs cancer) 12-3714598 (cancer vs cancer)

113498106 2

(cancer vs cancer) (cancer vs cancer)

1- cg0680796

cgl7020695 (cancer vs cancer) 12-4274034 (normal vs normal)

113498174 6

(cancer+normal vs cancer+normal)

1- 13- cg2462327

cg00058299 (cancer vs cancer) (cancer vs cancer)

113498193 100635002 1

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 13- cg2221925

cg23981150 (cancer+normal vs (normal vs normal)

161111090 32605406 4

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cgl694165

cgl5626828 (cancer vs cancer) (normal vs normal)

198651141 32605611 6

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 14- cg2303481

cg09517106 (cancer+normal vs (normal vs normal)

198904195 105714589 8

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 14- cgl547436

cgl3234569 (cancer vs cancer) (normal vs normal)

207818036 105714833 7

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 14- cgl656154

cg08110488 (cancer+normal vs (normal vs normal)

82136224 105714843 3

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

10- 14- cg0123756

cg06400428 (cancer vs cancer) (cancer vs cancer)

102107666 105715025 5

(normal vs normal) (cancer+normal vs cancer+normal)

10- 14- cg2281629

cg24503796 (cancer vs cancer) (cancer vs cancer)

102107676 22458634 4

10- 14- cg2296893 (cancer vs cancer) cg24127310 (cancer vs cancer)

102502104 37131555 6 (cancer vs cancer)

10- 14- cg2334798

cg02809409 (cancer vs cancer) (cancer vs cancer)

72218642 99737609 7

10- 15- cg0226035

cg09994553 (cancer vs cancer) (cancer vs cancer)

7859768 71185242 3

10- 15- cg0243043 (cancer vs cancer) cg08151063 (cancer vs cancer)

94459528 74532450 0 (cancer vs cancer)

11- 15- cg2245600

cgl4308313 (cancer vs cancer) (cancer vs cancer)

134336336 98447618 0

(cancer vs cancer)

11- cg0060996 (cancer vs cancer) cgl3165070 (cancer+normal vs 16-1202819

2154113 6 (cancer vs cancer) cancer+normal)

11- 16- cg0246347

cgl9323951 (cancer vs cancer) (cancer vs cancer)

64993076 30798048 8

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

11- 16- cg0798922

cg02675946 (cancer+normal vs (normal vs normal)

64993239 86231948 1

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

11- 16- cg0544103

cg27428304 (cancer vs cancer) (cancer+normal vs

64993281 89723364 9

cancer+normal)

11- (cancer vs cancer) 17- cg2676336 (cancer vs cancer) cg23930334

64993335 (normal vs normal) 18266135 2 (cancer vs cancer)

(cancer vs cancer)

12- 17- cg0807604

cgl l612617 (cancer vs cancer) (cancer+normal vs

102872937 26685074 4

cancer+normal)

12- 19- cg2158737

cg25832824 (cancer vs cancer) (cancer vs cancer)

108733253 49589626 2

(cancer vs cancer)

12- 19- cg0074177

cg03612522 (cancer+normal vs (cancer vs cancer)

108733261 51222459 4

cancer+normal)

(cancer vs cancer)

12- 19- cgl201840

cgl2142354 (cancer+normal vs (cancer vs cancer)

108733275 55677414 3

cancer+normal)

(cancer vs cancer)

12- 19- cg0143452

cgl5448445 (cancer+normal vs (cancer vs cancer)

108733308 55728628 3

cancer+normal)

(cancer vs cancer)

12- 2- cg0137682 (cancer vs cancer) cg03131366 (cancer vs cancer)

2041707 102804405 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- 2- cg0067489 (cancer vs cancer) cg25425078 (cancer+normal vs

4381777 102804576 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

12- 2- cg2679208

cgl5993083 (cancer vs cancer) (cancer+normal vs

4381788 200324879 0

cancer+normal)

12- 2- cg2122315

cg05481991 (cancer vs cancer) (cancer vs cancer)

66216880 215275783 9

(cancer vs cancer)

13- 2- cgl512576 (cancer vs cancer) cgl5120341 (cancer+normal vs

114238565 215275838 3 (cancer vs cancer) cancer+normal)

13- (cancer vs cancer) cgl634579

cg06476131 2-8816914 (cancer vs cancer)

47471052 (cancer+normal vs 5 cancer+normal)

13- cgl251536

cgl6188532 (cancer vs cancer) 2-8816922 (cancer vs cancer)

47471090 6

(cancer vs cancer)

13- 20- cgl678600

cg09361691 (cancer+normal vs (cancer vs cancer)

47471169 10200383 7

cancer+normal)

(cancer vs cancer)

14- 20- cg2320438

cg08054244 (cancer+normal vs (cancer vs cancer)

88789549 29994089 4

cancer+normal)

15- 20- cgl752630

cg04861263 (cancer vs cancer) (cancer vs cancer)

60298043 62793452 1

(cancer vs cancer)

15- 3- cg0005257 (cancer vs cancer) cg04672495 (cancer vs cancer)

76136875 132843565 8 (cancer+normal vs cancer+normal)

15- cgl531650

cgl8202336 (cancer vs cancer) 3-64008330 (cancer vs cancer)

99193993 8

15- cg0560035 (cancer vs cancer) cg01631855 (cancer vs cancer) 4-4858598

99194172 0 (cancer vs cancer)

15- cg0026775

cgl7297216 (cancer vs cancer) 4-4861618 (cancer vs cancer)

99194474 1

18- cgl 193059

cg21739658 (cancer vs cancer) 4-4861820 (cancer vs cancer)

24130367 2

18- 5- cgl366599

cg03284649 (cancer vs cancer) (cancer vs cancer)

52989085 102898478 8

19- 5- cgl602509 (cancer vs cancer) cg24571673 (cancer vs cancer)

39687568 175298655 4 (cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer)

19- 5- cgl356488 (cancer vs cancer) cg24449629 (cancer+normal vs

52646265 175298869 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

2- 6- cgOl 15607

cgl6205490 (cancer vs cancer) (cancer+normal vs

119077241 100064885 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

2- 6- cgl202362

cgl8110444 (cancer+normal vs (normal vs normal)

136743460 152623479 5

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

2- 6- cg2330983 (cancer vs cancer) cg27378835 (cancer vs cancer)

172950626 165341320 6 (cancer+normal vs cancer+normal)

(cancer vs cancer)

2- cg0268278

cg04737950 (cancer+normal vs 6-19804855 (cancer vs cancer)

71504771 9

cancer+normal)

(cancer vs cancer)

3- (normal vs normal) cgl712353

cg05293820 6-26204773 (cancer vs cancer)

120627406 (cancer+normal vs 4

cancer+normal)

3- cgl670663

cgl4961949 (cancer vs cancer) 6-26204823 (cancer vs cancer)

157824209 1

3- cg2713386 (cancer vs cancer) cgl7191178 (cancer vs cancer) 6-26216541

157824217 4 (cancer vs cancer)

3- cg0385486 (cancer vs cancer) cg06238409 (cancer vs cancer) 6-26224070

168864101 5 (cancer vs cancer)

3- cgl607001 (cancer vs cancer) cg25444208 (cancer vs cancer) 6-26224392

181431065 8 (cancer vs cancer)

(cancer vs cancer)

3- cg2444094

cg03827626 (cancer vs cancer) 6-26224668 (cancer vs cancer)

181431306 1

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

4- 7- cg2495625 (cancer vs cancer) cg20910303 (cancer+normal vs

147443095 139168481 0 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

4- 7- cg0959520 (cancer vs cancer)

_C gl4094460 (cancer+normal vs

43900946 156812104 2 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

4- 7- cg0257007

cg05899741 (cancer+normal vs (normal vs normal)

43901084 156814845 9

cancer+normal) (cancer+normal vs

cancer+normal)

4- cg0206768 (cancer vs cancer) cgl4660125 (cancer vs cancer) 7-25894793

89378460 8 (cancer vs cancer)

(cancer vs cancer) cgl376724

4-9534313 cgl5442990 (cancer vs cancer) 7-75831678 (cancer+normal vs

5

cancer+normal)

(cancer vs cancer)

5- cgl634621

cgl 1657018 (cancer+normal vs 7-83824255 (cancer vs cancer)

111115809 2

cancer+normal)

(cancer vs cancer)

5- (normal vs normal) cg0104352

cg23311108 7-99678668 (cancer vs cancer)

115387951 (cancer+normal vs 4

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- 8- cg2290481

cgl4690181 (cancer+normal vs (cancer+normal vs

115387984 135843385 5

cancer+normal) cancer+normal)

5- 8- cgl564050

cgl4319409 (cancer vs cancer) (cancer vs cancer)

151304409 145181395 3

5- cg2604543 (cancer vs cancer) cg03059048 (cancer vs cancer) 8-21987861

162930610 4 (cancer vs cancer)

5- cg0373229

cgl9597031 (cancer vs cancer) 8-57906837 (cancer vs cancer)

162931471 5

5- cgl384856 (cancer vs cancer) cgl6417447 (cancer vs cancer) 9-89561175

162931633 6 (cancer vs cancer)

5- cg05947699 (cancer vs cancer) Status - Hypo

173345670

5- cgl386376 (cancer vs cancer) cg26092471 (cancer vs cancer) 1-11561908

174150712 4 (cancer vs cancer)

5- cgl389767 (cancer vs cancer) cg25010361 (cancer vs cancer) 1-1374310

36607377 5 (cancer vs cancer)

5- cgl963947 (cancer vs cancer) cg21245981 (cancer vs cancer) 1-1374669

36607390 9 (cancer vs cancer)

(cancer vs cancer)

6- 1- cg2440877 (cancer vs cancer) cgl0414242 (cancer vs cancer)

151561447 203098067 6 (cancer+normal vs

cancer+normal)

6- 1- cgl010043

cg24036126 (cancer vs cancer) (cancer vs cancer)

26234819 223903862 7

6- 1- cg0984736

cg24855943 (cancer vs cancer) (cancer vs cancer)

26235224 230250326 8

6- 1- cg0056618

cgl8465515 (cancer vs cancer) (cancer vs cancer)

26273182 230250356 7

(cancer vs cancer) (cancer vs cancer)

6- cg0071799

cg06926499 (cancer+normal vs 1-44819838 (cancer+normal vs

27775877 5

cancer+normal) cancer+normal)

(cancer vs cancer)

6- cgl625081

cgl8943383 (cancer+normal vs 1-65299902 (cancer vs cancer)

27777858 2

cancer+normal) 6- 10- cg0839869

cgl5410276 (cancer vs cancer) (cancer vs cancer)

27778076 131217895 1

6- 10- cg0613909 (cancer vs cancer) cg07178031 (cancer vs cancer)

27778236 134499505 9 (cancer vs cancer)

(cancer vs cancer)

6- 10- cg0045845 (cancer vs cancer) cg20478264 (cancer vs cancer)

27782176 134499528 4 (cancer+normal vs cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl344114

cgl6347724 (cancer+normal vs (cancer vs cancer)

27782484 134499734 2

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 10- cg0254112 (cancer vs cancer)

_C g05444312 (cancer+normal vs

27782628 134499752 5 (cancer+normal vs cancer+normal)

cancer+normal)

6- cgl857080 (cancer vs cancer) cg00667898 (cancer vs cancer) 10-294353

27834966 0 (cancer vs cancer)

6- 10- cg0751028 (cancer vs cancer) cgl8798248 (cancer vs cancer)

27835460 90644018 2 (cancer vs cancer)

(cancer vs cancer)

6- 11- cg0616816 (cancer vs cancer) cgl2181621 (cancer vs cancer)

27840068 47372949 6 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 11- cgl035413 (cancer vs cancer) cg05511483 (cancer+normal vs

27840105 47372960 4 (cancer+normal vs cancer+normal)

cancer+normal)

6- 11- cg2726530

cg09556042 (cancer vs cancer) (cancer vs cancer)

31237013 67220318 7

(cancer vs cancer)

6- (normal vs normal) 11- cgl322870

cg25140213 (cancer vs cancer)

32522683 (cancer+normal vs 78614522 1

cancer+normal)

(cancer vs cancer)

6- 11- cgl872537

cg07984380 (cancer+normal vs (cancer vs cancer)

32547019 86142478 5

cancer+normal)

6- (cancer vs cancer) 11- cgl514646

cgl2867728 (cancer vs cancer)

32549283 (normal vs normal) 86142587 2

(cancer vs cancer) (cancer vs cancer)

7- 12- cgl721445

cgl4823389 (cancer+normal vs (cancer+normal vs

101398152 102216984 6

cancer+normal) cancer+normal)

(cancer vs cancer)

12- cg0539518

7-1250182 cg07919840 (cancer+normal vs (cancer vs cancer)

124913717 7

cancer+normal)

7- 12- cg2408542

cgl 1382477 (cancer vs cancer) (cancer vs cancer)

155264170 47583278 6

7- 12- cg0487690 (cancer vs cancer) cg24954668 (cancer vs cancer)

20833585 95711510 5 (cancer vs cancer)

7- 12- cg0316282

cg09420439 (cancer vs cancer) (cancer vs cancer)

27136424 95941571 3

8- 13- cgl373180 (cancer vs cancer) cg03245734 (cancer vs cancer)

108510096 101167901 0 (cancer vs cancer)

8- 13- cgl538974

cgl9275050 (cancer vs cancer) (cancer vs cancer)

122653619 50702675 9

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

9- 14- cg0152347

cgl3793166 (cancer+normal vs (cancer vs cancer)

123639954 45365651 4

cancer+normal) (cancer+normal vs cancer+normal) (cancer vs cancer)

9- 14- cg2110415

cg00429618 (cancer+normal vs (cancer vs cancer)

99962350 68040530 5

cancer+normal)

14- cg2503476

Status - Hypo (cancer vs cancer)

75747332 6

(cancer vs cancer)

1- 14- cg0303488

cg26035817 (cancer+normal vs (cancer vs cancer)

114414802 91720696 0

cancer+normal)

(cancer vs cancer)

1- 14- cg2313860 (cancer vs cancer) cg23093116 (cancer+normal vs

117489843 91770145 8 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

1- 14- cgl946560 (cancer vs cancer) cgl5553612 (cancer+normal vs

119520934 91770229 5 (cancer vs cancer) cancer+normal)

1- 15- cg0345531

cg09059988 (cancer vs cancer) (cancer vs cancer)

150693299 62516405 6

(cancer vs cancer)

1- 15- cg2595426 (cancer vs cancer) cgl 1143857 (cancer+normal vs

202559755 71092216 9 (cancer vs cancer) cancer+normal)

(normal vs normal)

(cancer vs cancer)

1- (cancer vs cancer) 16- cg0368115

cgl0175859 (cancer+normal vs

233817629 (cancer+normal vs 29857167 0

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 17- cgl976025

cgl5897613 (cancer+normal vs (cancer vs cancer)

23418405 36997627 0

cancer+normal)

(cancer vs cancer)

1- 17- cgl328206 (cancer vs cancer) cg08460387 (cancer+normal vs

26000291 73360252 8 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

1- 17- cg2177014

cgl0530613 (cancer+normal vs (cancer vs cancer)

40346530 79869997 5

cancer+normal)

(cancer vs cancer)

1- 17- cg0788519

cgl 1521979 (cancer+normal vs (cancer vs cancer)

67266410 80848209 1

cancer+normal)

(normal vs normal)

(cancer vs cancer) cgl638105

1-6855140 cg04874074 17-835927 (cancer vs cancer)

(cancer+normal vs 9

cancer+normal)

(cancer vs cancer)

10- 19- cg0266824

cgl5448683 (cancer+normal vs (cancer vs cancer)

102671221 16437789 8

cancer+normal)

(cancer vs cancer)

10- 19- cg0887394 (cancer vs cancer) cgl7182036 (cancer+normal vs

119101310 51607432 0 (cancer vs cancer) cancer+normal)

10- cgl833173

cgl4856220 (cancer vs cancer) 19-6742907 (cancer vs cancer)

123353500 2

(normal vs normal) (cancer vs cancer)

10- (normal vs normal) cg0593739

cg27405177 2-18736132 (cancer vs cancer)

134926810 (cancer vs cancer) 2

(cancer+normal vs cancer+normal)

(cancer vs cancer)

10- 2- cgl990729

cg27633010 (cancer+normal vs (cancer vs cancer)

135097477 217448253 3

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- 2- cg0400387 (cancer vs cancer) cg26552733 (cancer+normal vs

5542941 241290895 1 (cancer+normal vs

cancer+normal)

cancer+normal)

10- (cancer vs cancer) cg0818297 (normal vs normal) cg23077498 2-7164527

76801843 (cancer+normal vs 5 (cancer vs cancer) cancer+normal) (cancer vs cancer)

(cancer+normal vs cancer+normal)

(normal vs normal) (cancer vs cancer)

10- cg2099575

cgl4882291 (cancer vs cancer) 2-7164586 (cancer vs cancer)

92663320 3

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- cg0023076 (cancer vs cancer) cg24984532 (cancer+normal vs 2-9388337

93872745 6 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

11- (cancer vs cancer) 21- cg0718369

cgl8743034 (cancer vs cancer)

124539453 (cancer+normal vs 43241683 1

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- 22- cgl866155 (cancer vs cancer) cg26351663 (cancer+normal vs

126072352 29441760 0 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

11- 3- cg0827710

cg00458607 (cancer+normal vs (cancer vs cancer)

130763724 109115356 0

cancer+normal)

(cancer vs cancer)

11- 3- cg2067539

cg22756211 (cancer+normal vs (cancer vs cancer)

134118834 118864895 1

cancer+normal)

(cancer vs cancer)

11- 3- cg0580106 (cancer vs cancer) cgl2489547 (cancer vs cancer)

15959637 128079984 6 (cancer+normal vs cancer+normal)

(cancer vs cancer)

3- cg0629456 (cancer vs cancer)

11-232013 cgl4777131 (cancer vs cancer)

141161580 1 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 3- cgl 143172

cgl3363640 (cancer+normal vs (cancer+normal vs

2985302 149126842 3

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 3- cgl976096

cg24431193 (cancer+normal vs (cancer vs cancer)

63883947 194868843 5

cancer+normal)

11- cg2492405 (cancer vs cancer) cg27243121 (cancer vs cancer) 3-32408427

70281584 1 (cancer vs cancer)

(cancer vs cancer)

11- cg0631186 (cancer vs cancer) cgl2506582 (cancer+normal vs 3-55508686

75115584 3 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

11- cg2757105 (cancer vs cancer) cgl 1512797 (cancer vs cancer) 4-1646179

9448817 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

12- cg2630051

cg26459499 (cancer+normal vs 4-38732661 (cancer vs cancer)

11005841 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- cg0820607

cg23334507 (cancer+normal vs 4-8386188 (cancer+normal vs

46753241 9

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- cgl899918 (cancer vs cancer) cgl0052368 (cancer+normal vs 4-8386198

48163063 5 (cancer+normal vs cancer+normal)

cancer+normal)

12- (normal vs normal) cg2299393

cgl7430032 4-8477915 (cancer vs cancer)

64317120 (cancer vs cancer) 7 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

12- 5- cg0641683

cgl5354877

76102490 (cancer+normal vs (cancer vs cancer)

138474152 1

cancer+normal)

(cancer vs cancer)

13- 5- cg2530619

cg23052386

111553101 (cancer+normal vs (cancer vs cancer)

150131024 8

cancer+normal)

(cancer vs cancer)

13- cg2368847

cg25408055 (cancer vs cancer)

(cancer vs cancer)

113977663 5-42756851

9 (cancer+normal vs cancer+normal)

(normal vs normal)

13- (cancer vs cancer) cgl566382

cg21941987

114303277 5-64103336 (cancer vs cancer)

(cancer+normal vs 3

cancer+normal)

13- cg0020247

cgl5951545 (cancer vs cancer)

21547300 6-31760383 (cancer vs cancer)

9

(cancer vs cancer)

13- (cancer vs cancer) cg0085957

cg26286098 (cancer+normal vs

31905755 6-39159259 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

13- cgl003065

cgl3341441

44824424 (cancer+normal vs 6-56298004 (cancer vs cancer)

8

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

14- cg2093409

cg24961406 (cancer vs cancer)

23375575 (cancer+normal vs 7-1117418

6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

14- cg0813708

cgl8703243 (cancer vs cancer)

(cancer vs cancer)

62021555 7-1117540

5 (cancer+normal vs cancer+normal)

(cancer vs cancer)

14- 7- cg0965588

cgl 1849213

65210900 (cancer+normal vs (cancer vs cancer)

133083962 7

cancer+normal)

(cancer vs cancer)

14- 7- cg2052169

cglO 166090

68162924 (cancer+normal vs (cancer vs cancer)

155599780 6

cancer+normal)

14- cg2220491

cgl9000611 (cancer vs cancer)

92198288 7-17582718 (cancer vs cancer)

5

14- cg2191359

cgl 9749445 (cancer vs cancer)

92493378 7-23719453 (cancer vs cancer)

1

(cancer vs cancer)

15- cgl345749 (cancer vs cancer) cgl4588686

102261251 (cancer+normal vs 7-2609648

6 (cancer vs cancer) cancer+normal)

15- cgl 164625

cg25908613 (cancer vs cancer)

(cancer vs cancer)

25436246 7-34026657

9 (cancer vs cancer)

(normal vs normal)

15- (cancer vs cancer) cgl330193

cg09938490 (cancer vs cancer)

44088809 7-44526856

(cancer+normal vs 1 (cancer vs cancer) cancer+normal)

16- cg0879759

cg27347003 (cancer vs cancer)

(cancer vs cancer)

28915665 7-4751611

8 (cancer vs cancer)

(cancer vs cancer)

16- cg2764006

cg00345270 (cancer vs cancer)

29268157 (cancer+normal vs 7-4752983

4 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

16- cg0426149 (cancer vs cancer) cg07346700

71748967 (cancer+normal vs 7-4753002

6 (cancer vs cancer) cancer+normal)

16- (cancer vs cancer) cg0611460 (cancer vs cancer) cg06035645

89190857 7-4806755

(cancer+normal vs 5 (cancer vs cancer) cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- cg2533026 (cancer vs cancer) cg01559375 (cancer+normal vs 7-4806949

12924257 4 (cancer+normal vs cancer+normal)

cancer+normal)

17- cgl872491 (cancer vs cancer) cg26910001 (cancer vs cancer) 7-75357247

16838321 2 (cancer vs cancer)

(cancer vs cancer)

17- cgl939625 (normal vs normal) cg26026558 (cancer+normal vs 7-77584545

16934655 3 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

18- cgl892981 (cancer vs cancer) cg20368463 (cancer+normal vs 7-97875293

77673604 4 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

19- cgl856389 (cancer vs cancer) cgl2218406 (cancer vs cancer) 7-97875333

18120692 9 (cancer+normal vs cancer+normal)

19- 8- cgl652051

cg03014882 (cancer vs cancer) (cancer vs cancer)

18120728 130976125 9

(cancer vs cancer)

19- cgl810953 (cancer vs cancer) cg00474840 (cancer vs cancer) 8-17655156

18120819 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

2- cg2363044

cgl4475035 (cancer+normal vs 8-18245225 (cancer vs cancer)

111883501 2

cancer+normal)

2- cg0349028

cg26038022 (cancer vs cancer) 8-49729253 (cancer vs cancer)

144698389 9

(cancer vs cancer)

2- cgl664809 (normal vs normal) cg08776913 (cancer+normal vs 8-62412760

187451704 4 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

2- cg0557078

cgl 1793005 (cancer+normal vs 8-71016364 (cancer vs cancer)

36638660 3

cancer+normal)

(cancer vs cancer)

2- cgl943680

cgl4458626 (cancer+normal vs 8-8560866 (cancer vs cancer)

63834284 4

cancer+normal)

(cancer vs cancer)

2- 9- cgl450339

cgl4769556 (cancer+normal vs (cancer vs cancer)

65314733 126128745 5

cancer+normal)

20- cgl5511401 (cancer vs cancer) OV (cancer vs cancer)

13798846

(normal vs normal)

20- (cancer vs cancer)

cgl4637027 Status - Hyper

36033352 (cancer+normal vs

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- cgl549255

cgl5574461 (cancer+normal vs 1-1297576 (cancer+normal vs

36033357 2

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

21- (cancer vs cancer) 1- cg0684971

cgl9408149 (cancer+normal vs

43242428 (cancer+normal vs 205399945 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

22- 1- cgl422103

cg25564144 (cancer+normal vs (cancer+normal vs

36135459 205400120 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- 1- cg0696887

cgl3331610 (cancer+normal vs (cancer+normal vs

120156942 205400197 8

cancer+normal) cancer+normal) (cancer vs cancer)

3- 1- cg0359997 (normal vs normal) cg01051047 (cancer vs cancer)

122628121 219834537 8 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- 1- cg2668266

cg25087352 (cancer+normal vs (cancer+normal vs

24213704 219834581 4

cancer+normal) cancer+normal)

(cancer vs cancer)

3- cg0428603

cg20832448 (cancer vs cancer) 1-2313373 (cancer+normal vs

36418645 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- cg0090249

cgl6863190 (cancer+normal vs 1-45279638 (cancer+normal vs

37092193 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) cg0105943

4-4459401 cgl7360330 (cancer+normal vs 1-45279684 (cancer+normal vs

2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cg0490858

cg27624381 (cancer+normal vs 1-8229825 (cancer+normal vs

77917883 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- 10- cgl425541 (normal vs normal) cgl4660032 (cancer+normal vs

138702273 104417977 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- cg0125096

5-1809371 cgl2153106 (cancer+normal vs (cancer+normal vs

119256257 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cg2319634

cgl8879177 (cancer+normal vs (cancer+normal vs

105854768 24808256 6

cancer+normal) cancer+normal)

(cancer vs cancer)

6- 10- cg0608808

cg22290704 (cancer vs cancer) (cancer+normal vs

144167951 48952423 4

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cg0589895

cgl5404791 (cancer+normal vs (cancer+normal vs

16147669 74870240 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cg0170141

cg24134481 (cancer+normal vs (cancer+normal vs

167794374 74870311 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl421925

cg26922625 (cancer+normal vs (cancer+normal vs

31771646 76779305 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cg0761639

cgl5495717 (cancer+normal vs (cancer+normal vs

34231501 94452554 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl090540

cg27319730 (cancer+normal vs (cancer+normal vs

36237037 95327292 1

cancer+normal) cancer+normal)

(cancer vs cancer)

7- 10- cg0561344

cg21114407 (cancer vs cancer) (cancer+normal vs

106040839 95327305 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 10- cgl513344

cg20973561 (cancer+normal vs (cancer+normal vs

133218612 95327325 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 11- cgl243943

cg02717503 (cancer+normal vs (cancer+normal vs

157213736 129243219 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cgl l36861

7-1946447 cg25786640 (cancer+normal vs (cancer+normal vs

133582402 7

cancer+normal) cancer+normal)

7- (cancer vs cancer) 11- cgl 164399 (cancer vs cancer) cg23492432

30053497 (cancer+normal vs 57568305 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

7- 11- cgl219833

cg08832195 (cancer vs cancer) (cancer+normal vs

40047674 70692032 4

cancer+normal)

(cancer vs cancer)

8- 11- cg2017002

cg21896394 (cancer vs cancer) (cancer+normal vs

129099476 70917283 8

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 11- cg2571718

cg00267196 (cancer+normal vs (cancer+normal vs

135710113 76382149 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 12- cgl 133464

cgl3919506 (cancer+normal vs (cancer+normal vs

131535850 130529514 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 12- cg0615362

cgl4295534 (cancer+normal vs (cancer+normal vs

134004811 130529849 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 12- cgl623685

cgl4641829 (cancer+normal vs (cancer+normal vs

33270634 130529951 1

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer+normal vs 13- cgl541644

(cancer+normal vs cancer+normal) 110899996 0

cancer+normal)

(cancer vs cancer)

13- cg0900038

Status - Hyper (cancer+normal vs

41187926 5

cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 15- cg0791520

cg09360458 (cancer+normal vs

14075560 cancer+normal) 34260555 6

cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 15- cg2312934

cg08301542 (cancer+normal vs

145096567 cancer+normal) 39283510 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 15- cg0305138

cg23981150 (cancer+normal vs (cancer+normal vs

161111090 65197883 4

cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 16- cg0476172

cg25320221 (cancer+normal vs

183440909 cancer+normal) 10274315 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 16- cg0187972

cg09517106 (cancer+normal vs (cancer+normal vs

198904195 31821352 6

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

1- 17- cg0128655

cg24360513 (cancer+normal vs (cancer+normal vs

249120106 16284304 5

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

1- 17- cg2495617

cg00556029 (cancer+normal vs (cancer+normal vs

32802033 33542219 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer+normal vs 17- cgl054796 (normal vs normal)

1-567501 cg23917638

cancer+normal) 35084975 9 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 17- cg0443303

cg08110488 (cancer+normal vs (cancer+normal vs

82136224 36105064 5

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer+normal vs 17- cg0522234

cgl7187559 (cancer+normal vs

38146577 cancer+normal) 36105117 7

cancer+normal)

(cancer vs cancer)

10- (cancer+normal vs 17- cg0233580

cgl2515684 (cancer+normal vs

8203261 cancer+normal) 36105239 4

cancer+normal)

11- (cancer+normal vs 17- cg0155030 (cancer vs cancer) cg09333889

18211133 cancer+normal) 36204463 7 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 17- cg0832396

cgl3165070 (cancer+normal vs (cancer+normal vs

2154113 40770823 9

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer+normal vs 19- ^2704603

cg05323345 (cancer+normal vs

2163174 cancer+normal) 58280801 4

cancer+normal)

(cancer vs cancer)

11- (cancer+normal vs 19- cg0358453

cg27331871 (cancer+normal vs

2171478 cancer+normal) 58280832 5

cancer+normal)

(cancer vs cancer)

11- (cancer+normal vs 19- cg0768572

cg22830701 (cancer+normal vs

27527925 cancer+normal) 58280891 8

cancer+normal)

(cancer vs cancer)

11- (cancer+normal vs 19- cg22333733 t J1363688

(cancer+normal vs

31391482 cancer+normal) 58280927 0

cancer+normal)

(cancer vs cancer)

11- (cancer+normal vs 19- £429825

cg02294991 (cancer+normal vs

47927148 cancer+normal) 58280994 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 19- cg02675946 (cancer+normal vs t ^1857520

(cancer+normal vs

64993239 58281016 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 19- cg03612522 (cancer+normal vs t £075179

(cancer+normal vs

108733261 58281019 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 19- cgl2142354 (cancer+normal vs t £295641

(cancer+normal vs

108733275 58281117 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 19- cgl5448445 (cancer+normal vs t ^1403848

(cancer+normal vs

108733308 58281450 4

cancer+normal) cancer+normal)

(cancer vs cancer)

12- z ₉ (cancer vs cancer)

- ^1735488

cg25425078 (cancer+normal vs (cancer+normal vs

4381777 112658759 0

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

12- 2- cg0271559

cg24232869 (cancer+normal vs (cancer+normal vs

48478849 134325873 2

cancer+normal) cancer+normal)

(cancer vs cancer) vs cancer)

13- z ₉ (cancer

- cgl5120341 (cancer+normal vs t J1812334

(cancer+normal vs 114238565 134326055 4

cancer+normal) cancer+normal)

(cancer vs cancer)

13- z ₉ (cancer vs cancer)

- ^1898428

cg06476131 (cancer+normal vs (cancer+normal vs

47471052 134326172 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- 2- cg0407284

cg09361691 (cancer+normal vs (cancer+normal vs

47471169 170623948 3

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer+normal vs 2- cg0098213

cgl8899035 (cancer+normal vs

20811563 cancer+normal) 201726139 6

cancer+normal)

(cancer vs cancer)

14- (cancer+normal vs 2- cg0478431

cgl8073151 (cancer+normal vs

23452111 cancer+normal) 212609384 6

cancer+normal)

14- (cancer+normal vs z ₉ (cancer vs cancer)

- £524247

cg24043861 (cancer+normal vs

73396628 cancer+normal) 219738732 1

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- cg0475181

cg08054244 (cancer+normal vs 2-71192445 (cancer+normal vs

88789549 1

cancer+normal) cancer+normal)

(cancer vs cancer)

15- (cancer+normal vs 20- £483172

cg27542399 (cancer+normal vs

65281866 cancer+normal) 56025557 5

cancer+normal) (cancer vs cancer)

16- (cancer+normal vs 21- cg2038394

cg01709316

2732203 (cancer+normal vs cancer+normal) 46898137 8

cancer+normal)

(cancer vs cancer)

16- (cancer+normal vs

cg26627568 21- cgl663672

75032758 cancer+normal) (cancer+normal vs

47920571 1

cancer+normal)

(cancer vs cancer)

16- (cancer+normal vs 22- cgl816694

cg08839312

89237997 (cancer+normal vs cancer+normal) 18189443 7

cancer+normal)

17- (cancer vs cancer)

(cancer+normal vs 22- cg0423441

cg26114595

28395749 (cancer+normal vs cancer+normal) 24373322 2

cancer+normal)

(cancer vs cancer)

17- (cancer+normal vs 22- cg2120597

cgl3341633

29037254 cancer+normal) (cancer+normal vs

36044151 8

cancer+normal)

(cancer vs cancer)

17- (cancer+normal vs 22- cg0678153

cg24958366

46952555 cancer+normal) (cancer+normal vs

42077939 2

cancer+normal)

17- (cancer vs cancer)

(cancer+normal vs 22- cg0868609

cg21346818

46970413 (cancer+normal vs cancer+normal) 42078567 2

cancer+normal)

(cancer vs cancer)

19- (cancer+normal vs cg2557204

cg22460206 (normal vs normal)

3-15839627

37861707 cancer+normal) 3 (cancer+normal vs cancer+normal)

(normal vs normal) (cancer vs cancer)

19- 3- cgl4377791 cg0272390

(cancer+normal vs

40169912 (cancer+normal vs

160167768 4

cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer+normal vs 3- cgl247967

cg08533403

40854718 cancer+normal) (cancer+normal vs

160167789 4

cancer+normal)

(cancer vs cancer)

19- (cancer+normal vs

cgl7847861 cgl305262

3-47865946

40972683 cancer+normal) (cancer+normal vs

5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- cg0238870

c _g 24449629 (cancer+normal vs 3-4910253

52646265 (cancer+normal vs

9

cancer+normal) cancer+normal)

19- (cancer vs cancer)

(cancer+normal vs cg0762996

cgl7371487 3-50312389

9789027 (cancer+normal vs cancer+normal) 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cg0151174

cgl8110444 (cancer+normal vs 3-71112437

136743460 (cancer+normal vs

2

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer+normal vs cg0525729 (normal vs normal) cg07864632 4-1161247

230785697 cancer+normal) 1 (cancer+normal vs cancer+normal)

2- (cancer vs cancer)

(cancer+normal vs 4- cgl309989

cgl0828910

63850056 cancer+normal) (cancer+normal vs

174013995 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cgl466541

cg04737950 (cancer+normal vs 4-38859728

71504771 (cancer+normal vs cancer+normal) cancer+normal)

2- (normal vs normal) (cancer vs cancer) cgl460253

cg23655155 (cancer+normal vs 4-4859772

86332777 (cancer+normal vs

0

cancer+normal) cancer+normal)

20- (cancer vs cancer)

(cancer+normal vs c _g 2044499

cg03352975 4-649573

30327429 cancer+normal) (cancer+normal vs

0

cancer+normal)

20- (cancer+normal vs

cg27405321 cgl746787 (cancer vs cancer)

5-10307544

34359917 cancer+normal) 3 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer+normal vs cgl 188225

20-443331 cg04165120 5-10307634 (cancer+normal vs

cancer+normal) 2

cancer+normal)

(cancer vs cancer)

21- (cancer+normal vs cg0559334

cgl0405333 5-10307744

28516138 (cancer+normal vs

cancer+normal) 9

cancer+normal)

(cancer vs cancer)

21- (cancer+normal vs 5- cgl392597

cgl7499729

37504755 (cancer+normal vs

cancer+normal) 140502124 5

cancer+normal)

(cancer vs cancer)

21- (cancer+normal vs 5- cg0424614

cgl6267304

44985357 (cancer+normal vs

cancer+normal) 140739501 4

cancer+normal)

(normal vs normal) (cancer vs cancer)

22- 5- cgl 149902

cg01253545 (cancer+normal vs

31556314 (cancer+normal vs

140739655 5

cancer+normal) cancer+normal)

(cancer vs cancer)

22- (cancer+normal vs 5- cg0383560

cg05062854

32435553 (cancer+normal vs

cancer+normal) 140753418 9

cancer+normal)

(cancer vs cancer)

22- (cancer+normal vs cg0514557

cg07735571 5-1479911

39796170 (cancer+normal vs

cancer+normal) 3

cancer+normal)

(normal vs normal) (cancer vs cancer)

3- 5- cg0266630

cg05957736 (cancer+normal vs

111579326 (cancer+normal vs

180469248 2

cancer+normal) cancer+normal)

(cancer vs cancer)

3- (cancer+normal vs 5- cg2210268

cgl9231082

119217133 (cancer+normal vs

cancer+normal) 180486155 8

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (normal vs normal) cg0810796

cg05293820 6-24205566

120627406 (cancer+normal vs

(cancer+normal vs 0

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

3- cg2535455

cg07733481 (cancer+normal vs 6-8192098

122694286 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

3- (cancer+normal vs cg0510143

cg05555409 7-92262970

42641750 (cancer+normal vs

cancer+normal) 7

cancer+normal)

(normal vs normal)

4- (cancer vs cancer)

8- cg0177899

cgl0156125 (cancer+normal vs

115520072 (cancer+normal vs

134511683 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cg0548302

cg20910303 (cancer+normal vs 8-54569668

147443095 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cg2297346

_C gl4094460 (cancer+normal vs 8-54569817

43900946 (cancer+normal vs

8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cg0188799

cg05899741 (cancer+normal vs 8-54569999

43901084 (cancer+normal vs

5

cancer+normal) cancer+normal)

4- (cancer+normal vs

cgl6727027

57844010 Status - Hypo

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- 1- cg0245436

cgl 1657018 (cancer+normal vs

111115809 (cancer+normal vs

236156917 4

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- (normal vs normal) 1- cg0757821

cg23311108 (cancer+normal vs

115387951 (cancer+normal vs 236157114 5

cancer+normal) cancer+normal)

5- (cancer vs cancer) 1- cg0420418 (cancer vs cancer) cgl4690181

115387984 (cancer+normal vs 236157142 8 (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

1- cg0609481

5-1174666 cg02124887 (cancer+normal vs (cancer+normal vs

236157210 5

cancer+normal) cancer+normal)

(cancer vs cancer)

5- (cancer+normal vs cg2451301

cg22963133 1-7210826 (cancer+normal vs

53606234 cancer+normal) 4

cancer+normal)

(normal vs normal)

6- (cancer+normal vs cg0923445 (cancer vs cancer) cg20560186 1-94560697

109804103 cancer+normal) 4 (cancer+normal vs cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 10- cgl325321

cgl4765172 (cancer+normal vs

153304972 cancer+normal) 132365700 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- _C gl944849

cg06926499 (cancer+normal vs (cancer+normal vs

27775877 134246660 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl 179055

cgl8943383 (cancer+normal vs (cancer+normal vs

27777858 134593345 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl341880

cgl6347724 (cancer+normal vs (cancer+normal vs

27782484 134593418 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl989589

_C g05444312 (cancer+normal vs (cancer+normal vs

27782628 134593496 4

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 10- cgl683297

cg05729499 (cancer+normal vs

27832945 cancer+normal) 134593532 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cg0778388

cg05511483 (cancer+normal vs (cancer+normal vs

27840105 134593607 9

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 10- cg0459929

cg20738959 (cancer+normal vs

30539641 cancer+normal) 134996411 8

cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 10- cg2668458

cg03243683 (cancer+normal vs

31779637 cancer+normal) 38240973 1

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- (normal vs normal) 11- cg2640173

cg25140213 (cancer+normal vs

32522683 (cancer+normal vs 120998732 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 11- cg0543168

cg07984380 (cancer+normal vs (cancer+normal vs

32547019 130781542 4

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 11- cg0759280

cg03369465 (cancer+normal vs

33291367 cancer+normal) 17591873 9

cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 11- cg0626832

cgl2857652 (cancer+normal vs

64289969 cancer+normal) 63885740 7

cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 11- cgl767613

cgl9032326 (cancer+normal vs

66804704 cancer+normal) 63886204 2

cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 11- cgl671899

cgl3435101 (cancer+normal vs

74171350 cancer+normal) 64108790 9

cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs l icgl092542

cgl2344600 (cancer+normal vs

89769123 cancer+normal) es 124394 0

cancer+normal)

7- cgl4823389 (cancer vs cancer) 11- cg2411209 (cancer vs cancer) 101398152 (cancer+normal vs 69683619 1 (cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cg0877781

7-1250182 cg07919840 (cancer+normal vs (cancer+normal vs

70289549 2

cancer+normal) cancer+normal)

(cancer vs cancer)

7- (cancer+normal vs 11- cg0540167

cg27488370 (cancer+normal vs

128046294 cancer+normal) 70416309 0

cancer+normal)

(cancer vs cancer)

8- (cancer+normal vs 11- cgl423287

cg07229027 (cancer+normal vs

124408743 cancer+normal) 70458782 0

cancer+normal)

(normal vs normal) (cancer vs cancer)

8- 11- cg0480785

cg09373786 (cancer+normal vs (cancer+normal vs

93156639 73685776 6

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

9- 13- cgl 142313

cgl3796392 (cancer+normal vs (cancer+normal vs

102582694 112630656 0

cancer+normal) cancer+normal)

(cancer vs cancer)

9- (cancer+normal vs 13- cg0997521

cgl 1054680 (cancer+normal vs

123639935 cancer+normal) 113461500 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 13- cg0249094

cgl3793166 (cancer+normal vs (cancer+normal vs

123639954 113491766 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 13- cgl634173

cg00429618 (cancer+normal vs (cancer+normal vs

99962350 113634407 7

cancer+normal) cancer+normal)

(cancer vs cancer)

13- cgl792815

Status - Hypo (cancer+normal vs

113663206 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cg0290901

cg26035817 (cancer+normal vs (cancer+normal vs

114414802 113696937 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cg2474610

cg23093116 (cancer+normal vs (cancer+normal vs

117489843 113708289 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cgl604336

cgl5553612 (cancer+normal vs (cancer+normal vs

119520934 113744072 8

cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 13- cgl627713

cg26571535 (cancer+normal vs

151607108 cancer+normal) 113744320 9

cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 13- cg0261728

cg22443054 (cancer+normal vs

160314746 cancer+normal) 113796215 5

cancer+normal)

(normal vs normal) (cancer vs cancer)

1- 14- cgl368411

cg26428191 (cancer+normal vs (cancer+normal vs

185380011 101192634 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 14- cg0102184

cgl 1143857 (cancer+normal vs (cancer+normal vs

202559755 91806002 7

cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 15- cg0275963

cg22525895 (cancer+normal vs

207977042 cancer+normal) 22560713 5

cancer+normal)

(normal vs normal)

(cancer vs cancer)

1- (cancer vs cancer) 15- cg2400658

cgl0175859 (cancer+normal vs

233817629 (cancer+normal vs 45444508 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 15- cg0245012

cgl5897613 (cancer+normal vs (cancer+normal vs

23418405 58429751 4

cancer+normal) cancer+normal)

1- cg08460387 (cancer vs cancer) 16- cg0747219 (cancer vs cancer) 26000291 (cancer+normal vs 31453477 9 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 16- cg0217425

cgl0530613 (cancer+normal vs

40346530 (cancer+normal vs

85465268 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 16- cgl658108

cgl l521979 (cancer+normal vs

67266410 (cancer+normal vs

85465628 5

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer) 16- cg0141241

1-6855140 cg04874074 (cancer+normal vs

(cancer+normal vs 87856264 9

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer)

16- cgl5448683 cg0793307

(cancer+normal vs

102671221 (cancer+normal vs

88534585 8

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer)

16- cg0544534

cgl7182036 (cancer+normal vs

119101310 (cancer+normal vs

89219472 8

cancer+normal) cancer+normal)

10- (cancer vs cancer)

(cancer+normal vs 16- cg0503215

cgl3985270

133748048 (cancer+normal vs cancer+normal) 89219547 0

cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer) cgl215983

cg27633010 (cancer+normal vs 17-1069335

135097477 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer+normal vs

(cancer vs cancer)

10- cancer+normal)

cg05676341 cgl943585

17-2593076

135206831 (cancer+normal vs

(cancer+normal vs 9

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer) cg0630451

cg26552733 (cancer+normal vs 17-6024017

5542941 (cancer+normal vs

8

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer)

18- cgl977289

cg23077498 (cancer+normal vs

76801843 (cancer+normal vs

13263188 7

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer)

18- cg0159385

cg24984532 (cancer+normal vs

93872745 (cancer+normal vs

76725474 7

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

11- (cancer vs cancer) 19- cgl770238

cgl8743034

124539453 (cancer+normal vs

(cancer+normal vs 16466480 8

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer)

19- cg0473822

cg26351663 (cancer+normal vs

126072352 (cancer+normal vs

16466617 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cg2492893

cg00458607 (cancer+normal vs 19-4371934

130763724 (cancer+normal vs

8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cg22756211 19- cgl 145977

(cancer+normal vs

134118834 (cancer+normal vs

45262055 3

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) cg0271560

cgl3363640 (cancer+normal vs 19-4544446

2985302 (cancer+normal vs

2

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer)

2- cg0516801

cg24431193 (cancer+normal vs

63883947 (cancer+normal vs

102867275 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 2- cg0820042

cgl2506582 (cancer+normal vs

75115584 (cancer+normal vs

241896967 0

cancer+normal) cancer+normal)

12- (cancer vs cancer) cgl465711 (cancer vs cancer) cg26459499 2-72359477

11005841 (cancer+normal vs 6 (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

12- (cancer+nornial vs cg0971780

cg22694318 (cancer vs cancer)

2-74375930

117593728 cancer+normal) 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cg23334507 cg2307901

(cancer+normal vs 2-8343710

46753241 (cancer+normal vs

2

cancer+normal) cancer+normal)

12- (cancer vs cancer)

(cancer+normal vs

cg00966357 cg2011744

20-2308988

46945908 (cancer+normal vs cancer+normal) 7

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer)

22- cgl0052368 cgl292399

(cancer+normal vs

48163063 (cancer+normal vs

18277981 4

cancer+normal) cancer+normal)

(normal vs normal)

12- (cancer vs cancer) (cancer vs cancer)

3- cgl7430032 cg2518424

64317120 (cancer+normal vs

(cancer+normal vs 123813393 8

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer)

3- cgl5354877 cgl043069

(cancer+normal vs

76102490 (cancer+normal vs

123813596 0

cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer)

3- cg23052386 cg0885050

(cancer+normal vs

111553101 (cancer+normal vs

130368239 9

cancer+normal) cancer+normal)

(normal vs normal)

13- (cancer vs cancer) (cancer vs cancer)

3- cg21941987 cg0392054

114303277 (cancer+normal vs

(cancer+normal vs 196318703 4

cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer)

3- cg26286098 cgl228826

(cancer+normal vs

31905755 (cancer+normal vs

196318719 7

cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer)

3- cgl3341441 cgl605328

(cancer+normal vs

44824424 (cancer+normal vs

196387058 1

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) cg24961406 cgl257794

(cancer+normal vs 4-90168963

23375575 (cancer+normal vs

2

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) cgl l849213 5- cgl 984859

(cancer+normal vs

65210900 (cancer+normal vs

131658161 9

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) cgl0166090 cg2073873

(cancer+normal vs 5-13810195

68162924 (cancer+normal vs

5

cancer+normal) cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer) cgl4588686 cg0881882

(cancer+normal vs 5-13810279

102261251 (cancer+normal vs

9

cancer+normal) cancer+normal)

(normal vs normal)

15- (cancer vs cancer)

(cancer vs cancer)

cg09938490 cg0876139

5-42468836

44088809 (cancer+normal vs

(cancer+normal vs 6

cancer+normal) cancer+normal)

15- (cancer vs cancer)

(cancer+normal vs 6- cg0067893

cg21501234

64683155 cancer+normal) (cancer+normal vs

168378903 8

cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer)

6- cg00345270 cgl l l8169

(cancer+normal vs

29268157 (cancer+normal vs

169825345 3

cancer+normal) cancer+normal)

(cancer+normal vs

(cancer vs cancer)

16- cancer+normal)

cg27054887 cg0512956

6-30708009

67276940 (cancer+normal vs

(cancer+normal vs 8

cancer+normal) cancer+normal)

16- cg07346700 (cancer vs cancer) 6-31592082 cgOO 10791 (cancer vs cancer) 71748967 (cancer+normal vs 4 (cancer+normal vs cancer+normal) cancer+normal)

16- (cancer vs cancer)

(cancer+normal vs cgl325649

cgl6727006

87470545 6-42231123 (cancer+normal vs cancer+normal) 1

cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer)

7- cg06035645 cg0674631

89190857 (cancer+normal vs (cancer+normal vs

101755186 8

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer)

7- cg0750659

cg01559375

12924257 (cancer+normal vs (cancer+normal vs

157449217 9

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cg0273441

cg26026558

16934655 (cancer+normal vs 7-36339044 (cancer+normal vs

9

cancer+normal) cancer+normal)

(cancer vs cancer)

18- (cancer vs cancer) cg20368463 cgl206913

77673604 (cancer+normal vs 7-36585420 (cancer+normal vs

2

cancer+normal) cancer+normal)

(normal vs normal)

19- (cancer vs cancer) cg0345677

cgl 1437328

14171165 (cancer+normal vs 7-56242072 (cancer+normal vs

1

cancer+normal) cancer+normal)

19- (cancer vs cancer)

(cancer+normal vs 8- cgl777603

cgl4023449

44342834 (cancer+normal vs cancer+normal) 142841083 3

cancer+normal)

2- (cancer vs cancer)

(cancer+normal vs 8- cg0954179

cgO 1969473

102978461 (cancer+normal vs cancer+normal) 144872852 4

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer)

8- cgl028231

cgl4475035

111883501 (cancer+normal vs (cancer+normal vs

144873034 9

cancer+normal) cancer+normal)

2- (cancer vs cancer)

(cancer+normal vs 8- cgl843041

cg20740102

147933072 (cancer+normal vs cancer+normal) 144873183 1

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer)

8- cgOO 11204

cg08776913

187451704 (cancer+normal vs (cancer+normal vs

144958131 8

cancer+normal) cancer+normal)

(normal vs normal)

2- (cancer vs cancer) cgl903525

cgl2267933

228176991 (cancer+normal vs 8-43131260 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl 191275

cgl 1793005

36638660 (cancer+normal vs 8-48676898 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl493836

cgl4458626

63834284 (cancer+normal vs 8-49335020 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cg0072602

cgl4769556

65314733 (cancer+normal vs 8-49335078 (cancer+normal vs

9

cancer+normal) cancer+normal)

2- (cancer vs cancer)

(cancer+normal vs 9- cgl446997

cgl2600631

87420273 (cancer+normal vs cancer+normal) 140703588 2

cancer+normal)

(normal vs normal)

20- (cancer vs cancer)

(cancer vs cancer) 9- cgl287248

cgl4637027

36033352 (cancer+normal vs

(cancer+normal vs 140703637 9

cancer+normal) cancer+normal)

20- (cancer vs cancer) (cancer vs cancer) cg2096045

cgl5574461 (cancer+normal vs

36033357 9-99258799 (cancer+normal vs

6

cancer+normal) cancer+normal)

(normal vs normal)

21- (cancer vs cancer)

(cancer vs cancer) cgl416002

cgl9408149

43242428 9-99259456 (cancer+normal vs

(cancer+normal vs 0

cancer+normal) cancer+normal) (cancer vs cancer)

22- (cancer+normal vs

cg25564144 (cancer+normal vs

36135459 cancer+normal)

cancer+normal)

3- (cancer+normal vs

cg24599037

113405689 Status - Hyper

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- cgl549255

cgl3331610 (cancer+normal vs 1-1297576

120156942 (cancer+normal vs

2

cancer+normal) cancer+normal)

(cancer vs cancer)

3- (cancer+normal vs 1- cg0684971

cg27500716

138479392 (cancer+normal vs

cancer+normal) 205399945 9

cancer+normal)

(normal vs normal) (cancer vs cancer)

3- 1- cgl422103

cgl8802720 (cancer+normal vs

140992338 (cancer+normal vs

205400120 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- 1- cg0696887

cg25087352 (cancer+normal vs

24213704 (cancer+normal vs

205400197 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- 1- cg0359997 (normal vs normal) cgl6863190 (cancer+normal vs

37092193 219834537 8 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg2668266

4-4459401 cgl7360330 (cancer+normal vs (cancer+normal vs

219834581 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cg0428603

cg27624381 (cancer+normal vs 1-2313373

77917883 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- cg0090249

cgl4660032 (cancer+normal vs 1-45279638

138702273 (cancer+normal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) cg0105943

5-1809371 cgl2153106 (cancer+normal vs 1-45279684 (cancer+normal vs

2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- cg0490858

cgl8879177 (cancer+normal vs 1-8229825

105854768 (cancer+normal vs

8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 10- cgl425541 (normal vs normal) cgl5404791 (cancer+normal vs

16147669 104417977 7 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cg0125096

cg24134481 (cancer+normal vs

167794374 (cancer+normal vs

119256257 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cg2319634

cg26922625 (cancer+normal vs

31771646 (cancer+normal vs

24808256 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cg0608808

cgl5495717 (cancer+normal vs

34231501 (cancer+normal vs

48952423 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cg0589895

cg27319730 (cancer+normal vs

36237037 (cancer+normal vs

74870240 3

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 10- cg0170141

cgl0049156

44084209 (cancer+normal vs

cancer+normal) 74870311 5

cancer+normal)

(cancer vs cancer)

(cancer+normal vs 10- cgl421925

6-7414671 cgl0066132 (cancer+normal vs

cancer+normal) 76779305 6

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 10- cg0761639

cg20973561 (cancer+normal vs

133218612 (cancer+normal vs

94452554 4

cancer+normal) cancer+normal) (cancer vs cancer)

7- (cancer+normal vs 10- cgl090540

cgl4329833 (cancer+normal vs

134850443 cancer+normal) 95327292 1

cancer+normal)

(cancer vs cancer)

7- (cancer+normal vs 10- cg0561344

cg24952358 (cancer+normal vs

156561790 cancer+normal) 95327305 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 10- cgl513344

cg02717503 (cancer+normal vs (cancer+normal vs

157213736 95327325 8

cancer+normal) cancer+normal)

(cancer vs cancer)

7- (cancer+normal vs 11- cgl243943

cg24564603 (cancer+normal vs

158456404 cancer+normal) 129243219 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cgl l36861

7-1946447 cg25786640 (cancer+normal vs (cancer+normal vs

133582402 7

cancer+normal) cancer+normal)

(cancer vs cancer)

7- (cancer+normal vs 11- cgl 164399

cg24984423 (cancer+normal vs

23214241 cancer+normal) 57568305 1

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 11- cgl219833

cg23492432 (cancer+normal vs (cancer+normal vs

30053497 70692032 4

cancer+normal) cancer+normal)

(cancer vs cancer)

7- (cancer+normal vs 11- cg2017002

cg01196121 (cancer+normal vs

90890086 cancer+normal) 70917283 8

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 11- cg2571718

cg00267196 (cancer+normal vs (cancer+normal vs

135710113 76382149 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 12- cgl 133464

cgl3919506 (cancer+normal vs (cancer+normal vs

131535850 130529514 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 12- cg0615362

cgl4295534 (cancer+normal vs (cancer+normal vs

134004811 130529849 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 12- cgl623685

cgl4641829 (cancer+normal vs (cancer+normal vs

33270634 130529951 1

cancer+normal) cancer+normal)

(cancer vs cancer)

13- cgl541644

(normal vs normal) (cancer+normal vs

110899996 0

cancer+normal)

(cancer vs cancer)

13- cg0900038

Status - Hyper (cancer+normal vs

41187926 5

cancer+normal)

(cancer vs cancer)

1- 15- cg0791520

cg03942855 (normal vs normal) (cancer+normal vs

110210925 34260555 6

cancer+normal)

(cancer vs cancer)

1- 15- cg2312934

cg25593510 (normal vs normal) (cancer+normal vs

110254662 39283510 2

cancer+normal)

(cancer vs cancer)

1- 15- cg0305138

cg20803293 (normal vs normal) (cancer+normal vs

110254709 65197883 4

cancer+normal)

(cancer vs cancer)

1- 16- cg0476172

cg01701555 (normal vs normal) (cancer+normal vs

146544097 10274315 2

cancer+normal)

(cancer vs cancer)

1- 16- cg0187972

cgl2072973 (normal vs normal) (cancer+normal vs

150121727 31821352 6

cancer+normal)

(cancer vs cancer)

1- 17- cg0128655

cg09365446 (normal vs normal) (cancer+normal vs

150670422 16284304 5

cancer+normal)

1- cg03277515 (normal vs normal) 17- cg2495617 (cancer vs cancer) 153321198 33542219 6 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

1- 17- cgl054796 (normal vs normal) cgl9808620 (normal vs normal)

153514442 35084975 9 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

1- 17- cg0443303

cgl6312002 (normal vs normal) (cancer+normal vs

16554558 36105064 5

cancer+normal)

(cancer vs cancer)

1- 17- cg0522234

cg04365481 (normal vs normal) (cancer+normal vs

17086061 36105117 7

cancer+normal)

(cancer vs cancer)

1- 17- cg0233580

cg06346138 (normal vs normal) (cancer+normal vs

17086071 36105239 4

cancer+normal)

(normal vs normal) (cancer vs cancer)

1- 17- cg0155030

cg24360513 (cancer+normal vs (cancer+normal vs

249120106 36204463 7

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 17- cg0832396

cg27425314 (normal vs normal) (cancer+normal vs

26797619 40770823 9

cancer+normal)

(normal vs normal) (cancer vs cancer)

1- 19- cg2704603

cg00556029 (cancer+normal vs (cancer+normal vs

32802033 58280801 4

cancer+normal) cancer+normal)

(cancer vs cancer)

19- cg0358453

1-6265220 cgl9180828 (normal vs normal) (cancer+normal vs

58280832 5

cancer+normal)

(cancer vs cancer)

10- 19- cg0768572

cg24965984 (normal vs normal) (cancer+normal vs

113943723 58280891 8

cancer+normal)

(cancer vs cancer)

10- 19- cgl363688

cgl0862468 (normal vs normal) (cancer+normal vs

135342218 58280927 0

cancer+normal)

(cancer vs cancer)

10- 19- cg2429825

cgl0261325 (normal vs normal) (cancer+normal vs

29874759 58280994 5

cancer+normal)

(cancer vs cancer)

10- 19- cgl857520

cg00479240 (normal vs normal) (cancer+normal vs

30347670 58281016 9

cancer+normal)

(cancer vs cancer)

10- 19- cg2075179

cg22757362 (normal vs normal) (cancer+normal vs

43721445 58281019 5

cancer+normal)

(cancer vs cancer)

11- 19- cg2295641

cg08986368 (normal vs normal) (cancer+normal vs

2159122 58281117 0

cancer+normal)

(cancer vs cancer)

11- 19- cgl403848

cgl3756879 (normal vs normal) (cancer+normal vs

2161473 58281450 4

cancer+normal)

(cancer vs cancer)

11- 2- cgl735488

cg09864245 (normal vs normal) (cancer+normal vs

33746426 112658759 0

cancer+normal)

(cancer vs cancer)

11- 2- cg0271559

cg23153338 (normal vs normal) (cancer+normal vs

4615540 134325873 2

cancer+normal)

(cancer vs cancer)

11- 2- cgl812334

cg00270878 (normal vs normal) (cancer+normal vs

64334217 134326055 4

cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) 2- cgl898428

cg23930334 (cancer+normal vs

64993335 (normal vs normal) 134326172 2

cancer+normal)

11- cg07873178 (normal vs normal) 2- cg0407284 (cancer vs cancer) 65307616 170623948 3 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

11- 2- cg0098213

cg04089426 (normal vs normal) (cancer+normal vs

65307791 201726139 6

cancer+normal)

(cancer vs cancer)

11- 2- cg0478431

cg00206168 (normal vs normal) (cancer+normal vs

65308501 212609384 6

cancer+normal)

(cancer vs cancer)

11- 2- cg2524247

cgl7256240 (normal vs normal) (cancer+normal vs

71276557 219738732 1

cancer+normal)

(cancer vs cancer)

12- cg0475181

cgl5341350 (normal vs normal) 2-71192445 (cancer+normal vs

119446891 1

cancer+normal)

(cancer vs cancer)

12- 20- cg2483172

cg06601685 (normal vs normal) (cancer+normal vs

122277439 56025557 5

cancer+normal)

(cancer vs cancer)

12- 21- cg2038394

cg02571819 (normal vs normal) (cancer+normal vs

124017613 46898137 8

cancer+normal)

(cancer vs cancer)

13- 21- cgl663672

cg21900495 (normal vs normal) (cancer+normal vs 28498161 47920571 1

cancer+normal)

(cancer vs cancer)

13- 22- cgl816694

cgl6302790 (normal vs normal) (cancer+normal vs

28498334 18189443 7

cancer+normal)

(cancer vs cancer)

13- 22- cg0423441

cgl6300300 (normal vs normal) (cancer+normal vs

28501366 24373322 2

cancer+normal)

(cancer vs cancer)

13- 22- cg2120597

cg08100687 (normal vs normal) (cancer+normal vs

28502630 36044151 8

cancer+normal)

(cancer vs cancer)

14- 22- cg0678153

cgl0366062 (normal vs normal) (cancer+normal vs

103396161 42077939 2

cancer+normal)

(cancer vs cancer)

15- 22- cg0868609

cgl3800209 (normal vs normal) (cancer+normal vs

37390284 42078567 2

cancer+normal)

(cancer vs cancer)

15- cg2557204 (normal vs normal) cg22078710 (normal vs normal) 3-15839627

53087599 3 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

16- 3- cg0272390

cg08935125 (normal vs normal) (cancer+normal vs

3068085 160167768 4

cancer+normal)

(cancer vs cancer)

16- 3- cgl247967

cg06643150 (normal vs normal) (cancer+normal vs

3201981 160167789 4

cancer+normal)

(cancer vs cancer)

16- cgl305262

cgOO 170620 (normal vs normal) 3-47865946 (cancer+normal vs

56669038 5

cancer+normal)

(cancer vs cancer)

16- cg0238870

cg26919100 (normal vs normal) 3-4910253 (cancer+normal vs

67695516 9

cancer+normal)

(cancer vs cancer)

17- cg0762996

cg25826404 (normal vs normal) 3-50312389 (cancer+normal vs 18061566 5

cancer+normal)

(cancer vs cancer)

17- cg0151174

cg06503831 (normal vs normal) 3-71112437 (cancer+normal vs

26634225 2

cancer+normal)

17- cg03741619 (normal vs normal) 4-1161247 cg0525729 (cancer vs cancer) 3438918 1 (normal vs normal)

(cancer+normal vs cancer+normal)

(cancer vs cancer)

17- 4- cgl309989

cgl7035997 (normal vs normal) (cancer+normal vs

40705708 174013995 2

cancer+normal)

(cancer vs cancer)

17- (normal vs normal) cgl466541

cg02395846 4-38859728 (cancer+normal vs

43037309 (normal vs normal) 3

cancer+normal)

(cancer vs cancer)

17- cgl460253

cgOO 164949 (normal vs normal) 4-4859772 (cancer+normal vs

43037427 0

cancer+normal)

(cancer vs cancer)

17- cg2044499

cgl8056600 (normal vs normal) 4-649573 (cancer+normal vs

4642047 0

cancer+normal)

(cancer vs cancer)

17- cgl746787

cg02856727 (normal vs normal) 5-10307544 (cancer+normal vs 61959416 3

cancer+normal)

(cancer vs cancer)

19- cgl 188225

cgl9006008 (normal vs normal) 5-10307634 (cancer+normal vs

16999768 2

cancer+normal)

(cancer vs cancer)

19- cg0559334

cg01515960 (normal vs normal) 5-10307744 (cancer+normal vs

2494587 9

cancer+normal)

(normal vs normal) (cancer vs cancer)

19- 5- cgl392597

cgl4377791 (cancer+normal vs (cancer+normal vs

40169912 140502124 5

cancer+normal) cancer+normal)

(cancer vs cancer)

19- 5- cg0424614

cg22933807 (normal vs normal) (cancer+normal vs

47925425 140739501 4

cancer+normal)

(cancer vs cancer)

19- 5- cgl 149902

cgl6594139 (normal vs normal) (cancer+normal vs

49340574 140739655 5

cancer+normal)

(cancer vs cancer)

19- 5- cg0383560

cgl4941172 (normal vs normal) (cancer+normal vs

56733045 140753418 9

cancer+normal)

(cancer vs cancer)

2- cg0514557

cgl0687131 (normal vs normal) 5-1479911 (cancer+normal vs

20871002 3

cancer+normal)

(cancer vs cancer)

2- 5- cg0266630

cgl9147129 (normal vs normal) (cancer+normal vs

74230310 180469248 2

cancer+normal)

(normal vs normal) (cancer vs cancer)

2- 5- cg2210268

cg23655155 (cancer+normal vs (cancer+normal vs

86332777 180486155 8

cancer+normal) cancer+normal)

(cancer vs cancer)

20- cg0810796

cg07023803 (normal vs normal) 6-24205566 (cancer+normal vs

3389329 0

cancer+normal)

(cancer vs cancer)

22- cg2535455

cgl3248581 (normal vs normal) 6-8192098 (cancer+normal vs 17680545 1

cancer+normal)

(normal vs normal) (cancer vs cancer)

3- cg0510143

cg05957736 (cancer+normal vs 7-92262970 (cancer+normal vs

111579326 7

cancer+normal) cancer+normal)

(cancer vs cancer)

3- 8- cg0177899

cg24129382 (normal vs normal) (cancer+normal vs

119529158 134511683 4

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (normal vs normal) cg0548302

cg05293820 8-54569668 (cancer+normal vs

120627406 (cancer+normal vs 1

cancer+normal) cancer+normal) (normal vs normal) (cancer vs cancer)

3- cg2297346

cg07733481 (cancer+normal vs 8-54569817 (cancer+normal vs

122694286 8

cancer+normal) cancer+normal)

(cancer vs cancer)

3- cg0188799

cgl8082337 (normal vs normal) 8-54569999 (cancer+normal vs

147113726 5

cancer+normal)

3- cgl6636671 (normal vs normal) Status - Hypo

147126403

(cancer vs cancer)

3- 1- cg0245436

cgl2204258 (normal vs normal) (cancer+normal vs

147131178 236156917 4

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (normal vs normal) 1- cg0757821

cgl2727374 (cancer+normal vs

183542914 (cancer+normal vs 236157114 5

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (normal vs normal) 1- cg0420418

cg09738156 (cancer+normal vs

183543587 (cancer+normal vs 236157142 8

cancer+normal) cancer+normal)

(cancer vs cancer)

3- 1- cg0609481

cg07061775 (normal vs normal) (cancer+normal vs

196466494 236157210 5

cancer+normal)

(cancer vs cancer)

3- cg2451301

cgl5789250 (normal vs normal) 1-7210826 (cancer+normal vs

38207809 4

cancer+normal)

(normal vs normal)

3- cg0923445 (cancer vs cancer) cg04432377 (normal vs normal) 1-94560697

45017297 4 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

3- 10- cgl325321

cgl5865150 (normal vs normal) (cancer+normal vs

49757134 132365700 0

cancer+normal)

(normal vs normal) (cancer vs cancer)

4- 10- _C gl944849

cgl0156125 (cancer+normal vs (cancer+normal vs

115520072 134246660 7

cancer+normal) cancer+normal)

(cancer vs cancer)

10- cgl 179055

4-2404284 cg01601518 (normal vs normal) (cancer+normal vs

134593345 1

cancer+normal)

(cancer vs cancer)

4- 10- cgl341880

cgl2929487 (normal vs normal) (cancer+normal vs

41869175 134593418 4

cancer+normal)

(cancer vs cancer)

4- 10- cgl989589

cgl5264681 (normal vs normal) (cancer+normal vs

41884669 134593496 4

cancer+normal)

(cancer vs cancer)

5- 10- cgl683297

cg21634602 (normal vs normal) (cancer+normal vs

112073570 134593532 5

cancer+normal)

(cancer vs cancer)

10- cg0778388

5-1174646 cgl 1100933 (normal vs normal) (cancer+normal vs

134593607 9

cancer+normal)

(normal vs normal) (cancer vs cancer)

10- cg0459929

5-1174666 cg02124887 (cancer+normal vs (cancer+normal vs

134996411 8

cancer+normal) cancer+normal)

(cancer vs cancer)

5- 10- cg2668458

cg01159515 (normal vs normal) (cancer+normal vs

127420616 38240973 1

cancer+normal)

(cancer vs cancer)

5- 11- cg2640173

cg00076195 (normal vs normal) (cancer+normal vs

140892677 120998732 2

cancer+normal)

5- 11- cg0543168 (cancer vs cancer) cg07682041 (normal vs normal)

170763967 130781542 4 (cancer+normal vs cancer+normal)

(cancer vs cancer)

5- 11- cg0759280

cgl7679824 (normal vs normal) (cancer+normal vs

65018933 17591873 9

cancer+normal)

(cancer vs cancer)

6- 11- cg0626832

cgO 1177470 (normal vs normal) (cancer+normal vs

27870695 63885740 7

cancer+normal)

(cancer vs cancer)

6- 11- cgl767613

cgl5415945 (normal vs normal) (cancer+normal vs

31627678 63886204 2

cancer+normal)

(cancer vs cancer)

6- 11- cgl671899

cg08481075 (normal vs normal) (cancer+normal vs

33161328 64108790 9

cancer+normal)

(cancer vs cancer)

6- l icgl092542

cgl9156220 (normal vs normal)

33244752 es (cancer+normal vs

124394 0

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 11- cg2411209

cgl7225129 (cancer+normal vs

33244755 (normal vs normal) 69683619 1

cancer+normal)

(cancer vs cancer)

7- 11- cg0877781

cg02945056 (normal vs normal) (cancer+normal vs

127225891 70289549 2

cancer+normal)

(cancer vs cancer)

7- 11- cg0540167

cgl2744031 (normal vs normal) (cancer+normal vs

158751184 70416309 0

cancer+normal)

(cancer vs cancer)

7- 11- cgl423287

cg21001184 (normal vs normal) (cancer+normal vs

27205262 70458782 0

cancer+normal)

(cancer vs cancer)

11- cg0480785

8-1729607 cg09410841 (normal vs normal) (cancer+normal vs

73685776 6

cancer+normal)

(cancer vs cancer)

8- 13- cgl l42313

cgl4195684 (normal vs normal) (cancer+normal vs

74660125 112630656 0

cancer+normal)

(normal vs normal) (cancer vs cancer)

9- 13- cg0997521

cgl3796392 (cancer+normal vs (cancer+normal vs

102582694 113461500 9

cancer+normal) cancer+normal)

(cancer vs cancer)

9- 13- cg0249094

cgl5083233 (normal vs normal) (cancer+normal vs

112810402 113491766 2

cancer+normal)

(cancer vs cancer)

9- 13- cgl634173

cg27650175 (normal vs normal) (cancer+normal vs

124461640 113634407 7

cancer+normal)

(cancer vs cancer)

13- cgl792815

Status - Hypo (cancer+normal vs

113663206 2

cancer+normal)

(cancer vs cancer)

1- 13- cg0290901

cg25004385 (normal vs normal) (cancer+normal vs

147097078 113696937 8

cancer+normal)

(normal vs normal) (cancer vs cancer)

1- 13- cg2474610

cg26428191 (cancer+normal vs (cancer+normal vs

185380011 113708289 6

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 13- cgl604336

cgl8918637 (normal vs normal) (cancer+normal vs

228607587 113744072 8

cancer+normal)

(normal vs normal)

(cancer vs cancer)

1- (cancer vs cancer) 13- cgl627713

cgl0175859 (cancer+normal vs

233817629 (cancer+normal vs 113744320 9

cancer+normal) cancer+normal)

1- 13- cg0261728 (cancer vs cancer) cg22166914 (normal vs normal)

53195759 113796215 5 (cancer+normal vs cancer+normal)

(cancer vs cancer)

1- 14- cgl368411

cgl4969361 (normal vs normal) (cancer+normal vs

55464084 101192634 5

cancer+normal)

(cancer vs cancer)

1- 14- cg0102184

cg22029640 (normal vs normal) (cancer+normal vs

55501145 91806002 7

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer) 15- cg0275963

1-6855140 cg04874074 (cancer+normal vs

(cancer+normal vs 22560713 5

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (normal vs normal) 15- cg2400658

cg27405177 (cancer+normal vs

134926810 (cancer vs cancer) 45444508 2

cancer+normal)

(normal vs normal)

(cancer vs cancer)

10- (normal vs normal) 15- cg0245012

cgl9197922 (cancer+normal vs

16566625 (cancer+normal vs 58429751 4

cancer+normal) cancer+normal)

(cancer vs cancer)

10- 16- cg0747219

cgl5708219 (normal vs normal) (cancer+normal vs

22621481 31453477 9

cancer+normal)

(cancer vs cancer)

10- 16- cg0217425

cg22534759 (normal vs normal) (cancer+normal vs

32403029 85465268 2

cancer+normal)

(cancer vs cancer)

10- 16- cgl658108

cg08738443 (normal vs normal) (cancer+normal vs

8487762 85465628 5

cancer+normal)

(cancer vs cancer)

10- 16- cg0141241

cg26593228 (normal vs normal) (cancer+normal vs

88610737 87856264 9

cancer+normal)

(cancer vs cancer)

10- 16- cg0793307

cgl6289751 (normal vs normal) (cancer+normal vs

97889373 88534585 8

cancer+normal)

(normal vs normal)

(cancer vs cancer)

11- (cancer vs cancer) 16- cg0544534

cgl8743034 (cancer+normal vs

124539453 (cancer+normal vs 89219472 8

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 16- cg0503215

cg22205341 (normal vs normal) (cancer+normal vs

126611424 89219547 0

cancer+normal)

(cancer vs cancer)

11- cgl215983

cgl6363146 (normal vs normal) 17-1069335 (cancer+normal vs

22689281 7

cancer+normal)

(cancer vs cancer)

11- cgl943585

cgl4311630 (normal vs normal) 17-2593076 (cancer+normal vs

57363669 9

cancer+normal)

(cancer vs cancer)

11- cg0630451

cg23360860 (normal vs normal) 17-6024017 (cancer+normal vs

91717555 8

cancer+normal)

(cancer vs cancer)

12- 18- cgl977289

cgl5856066 (normal vs normal) (cancer+normal vs

132971019 13263188 7

cancer+normal)

(cancer vs cancer)

18- cg0159385

12-150865 cg26523196 (normal vs normal) (cancer+normal vs

76725474 7

cancer+normal)

(cancer vs cancer)

12- 19- cgl770238

cgl 1497017 (normal vs normal) (cancer+normal vs

63117540 16466480 8

cancer+normal)

(normal vs normal) (cancer vs cancer)

12- 19- cg0473822

cgl7430032 (cancer vs cancer) (cancer+normal vs

64317120 16466617 0

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

12- cg2492893

cg22253541 (normal vs normal) 19-4371934 (cancer+normal vs

65385603 8

cancer+normal)

(cancer vs cancer)

13- 19- cgl 145977

cg23511851 (normal vs normal) (cancer+normal vs

108087589 45262055 3

cancer+normal)

(cancer vs cancer)

13- cg0271560

cgl4219365 (normal vs normal) 19-4544446 (cancer+normal vs

113674587 2

cancer+normal)

(normal vs normal)

(cancer vs cancer)

13- (cancer vs cancer) 2- cg0516801

cg21941987 (cancer+normal vs

114303277 (cancer+normal vs 102867275 2

cancer+normal) cancer+normal)

(cancer vs cancer)

13- 2- cg0820042

cgl4984162 (normal vs normal) (cancer+normal vs

114776704 241896967 0

cancer+normal)

(cancer vs cancer)

13- cgl465711

cgl7877237 (normal vs normal) 2-72359477 (cancer+normal vs

32497491 6

cancer+normal)

(normal vs normal)

13- cg0971780 (cancer vs cancer) cg22095128 (normal vs normal) 2-74375930

33754450 9 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

13- cg2307901

cg22046318 (normal vs normal) 2-8343710 (cancer+normal vs 35212111 2

cancer+normal)

(cancer vs cancer)

14- cg2011744

cgl4839386 (normal vs normal) 20-2308988 (cancer+normal vs

102481497 7

cancer+normal)

(cancer vs cancer)

14- 22- cgl292399

cgl0146780 (normal vs normal) (cancer+normal vs

52897968 18277981 4

cancer+normal)

(cancer vs cancer)

14- 3- cg2518424

cg09993711 (normal vs normal) (cancer+normal vs

64746129 123813393 8

cancer+normal)

(cancer vs cancer)

14- 3- cgl043069

cg26578476 (normal vs normal) (cancer+normal vs

71250277 123813596 0

cancer+normal)

(cancer vs cancer)

14- 3- cg0885050

cgl2167284 (normal vs normal) (cancer+normal vs

91592793 130368239 9

cancer+normal)

(cancer vs cancer)

15- 3- cg0392054

cgl5183258 (normal vs normal) (cancer+normal vs

42061865 196318703 4

cancer+normal)

(cancer vs cancer)

15- 3- cgl228826

cgl4299369 (normal vs normal) (cancer+normal vs

43560165 196318719 7

cancer+normal)

(normal vs normal)

(cancer vs cancer)

15- (cancer vs cancer) 3- cgl605328

cg09938490 (cancer+normal vs

44088809 (cancer+normal vs 196387058 1

cancer+normal) cancer+normal)

(cancer vs cancer)

15- cgl257794

cg23100955 (normal vs normal) 4-90168963 (cancer+normal vs

61889439 2

cancer+normal)

(cancer vs cancer)

15- 5- cgl984859

cg26296941 (normal vs normal) (cancer+normal vs

93114062 131658161 9

cancer+normal)

(cancer vs cancer)

16- cg2073873

cg08255211 (normal vs normal) 5-13810195 (cancer+normal vs

6067801 5

cancer+normal) (cancer vs cancer)

16- cg0881882

cg08673532 (normal vs normal) 5-13810279 (cancer+normal vs

87422913 9

cancer+normal)

(cancer vs cancer)

17- cg0876139

cg27260984 (normal vs normal) 5-42468836 (cancer+normal vs

13399070 6

cancer+normal)

(cancer vs cancer)

17- 6- cg0067893

cg23371655 (normal vs normal) (cancer+normal vs

4225165 168378903 8

cancer+normal)

(cancer vs cancer)

17- 6- cgl l l8169

cgl4819820 (normal vs normal) (cancer+normal vs

56246435 169825345 3

cancer+normal)

(cancer vs cancer)

18- cg0512956

cgl5231809 (normal vs normal) 6-30708009 (cancer+normal vs

14747082 8

cancer+normal)

(cancer vs cancer)

18- cg0010791

cgl4572895 (normal vs normal) 6-31592082 (cancer+normal vs

61368902 4

cancer+normal)

(cancer vs cancer)

18- cgl325649

cgl6167782 (normal vs normal) 6-42231123 (cancer+normal vs

72925371 1

cancer+normal)

(normal vs normal) (cancer vs cancer)

19- 7- cg0674631

cgl 1437328 (cancer+normal vs (cancer+normal vs 14171165 101755186 8

cancer+normal) cancer+normal)

(cancer vs cancer)

19- 7- cg0750659

cg09404289 (normal vs normal) (cancer+normal vs

54208517 157449217 9

cancer+normal)

(cancer vs cancer)

19- cg0273441

cgl3518366 (normal vs normal) 7-36339044 (cancer+normal vs

55417390 9

cancer+normal)

(cancer vs cancer) cgl206913

2-1051469 cgl4174583 (normal vs normal) 7-36585420 (cancer+normal vs

2

cancer+normal)

(cancer vs cancer)

2- cg0345677

cg25707877 (normal vs normal) 7-56242072 (cancer+normal vs

109889899 1

cancer+normal)

(cancer vs cancer)

2- 8- cgl777603

cg25020810 (normal vs normal) (cancer+normal vs

129100899 142841083 3

cancer+normal)

(cancer vs cancer)

2- 8- cg0954179

cg27402713 (normal vs normal) (cancer+normal vs

130831550 144872852 4

cancer+normal)

(cancer vs cancer)

2- 8- cgl028231

cgl8966810 (normal vs normal) (cancer+normal vs

134368695 144873034 9

cancer+normal)

(cancer vs cancer)

2- 8- cgl843041

cgl4288266 (normal vs normal) (cancer+normal vs

204737672 144873183 1

cancer+normal)

(cancer vs cancer)

2- 8- cgOO 11204

cgl9773547 (normal vs normal) (cancer+normal vs

216252792 144958131 8

cancer+normal)

(cancer vs cancer)

2- cgl903525

cgl3432007 (normal vs normal) 8-43131260 (cancer+normal vs

221491208 4

cancer+normal)

(normal vs normal) (cancer vs cancer)

2- cgl l91275

cgl2267933 (cancer+normal vs 8-48676898 (cancer+normal vs

228176991 4

cancer+normal) cancer+normal)

(cancer vs cancer)

2- cgl493836

cg26354721 (normal vs normal) 8-49335020 (cancer+normal vs

39209066 0

cancer+normal)

2- cgl6101804 (normal vs normal) 8-49335078 cg0072602 (cancer vs cancer) 71194638 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

2- 9- cgl446997

cgl5454811 (normal vs normal) (cancer+normal vs

81428108 140703588 2

cancer+normal)

(cancer vs cancer)

9- cgl287248

2-8997977 cgl4820213 (normal vs normal) (cancer+normal vs

140703637 9

cancer+normal)

(normal vs normal)

(cancer vs cancer)

20- (cancer vs cancer) cg2096045

cgl4637027 9-99258799 (cancer+normal vs

36033352 (cancer+normal vs 6

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

21- (cancer vs cancer) cgl416002

cgl9408149 9-99259456 (cancer+normal vs

43242428 (cancer+normal vs 0

cancer+normal) cancer+normal)

22- PAAD (cancer vs

cg06838028 (normal vs normal)

41604442 cancer)

(normal vs normal)

3- cgl8802720 (cancer+normal vs Status - Hyper

140992338

cancer+normal)

3- cgl378825 (cancer vs cancer) cgl4218037 (normal vs normal) 1-13840381

155838032 8 (cancer vs cancer)

3- cg2307112 (cancer vs cancer) cgl7224181 (normal vs normal) 1-13840480

42064950 0 (cancer vs cancer)

3- cg2653618 (cancer vs cancer) cgl3414750 (normal vs normal) 1-13840494

53782863 9 (cancer vs cancer)

3- cgOl 14493 (cancer vs cancer) cg25855565 (normal vs normal) 1-13840612

73436384 3 (cancer vs cancer)

(cancer vs cancer)

4- 1- cg0015385 (cancer vs cancer) cgl5185864 (normal vs normal)

186349449 182584341 6 (cancer+normal vs cancer+normal)

(cancer vs cancer)

1- cg0714429 (normal vs normal)

4-567537 cgl4945316 (normal vs normal)

182584520 6 (cancer+normal vs cancer+normal)

(cancer vs cancer)

4- 1- cg2408589 (normal vs normal) cgl7837792 (normal vs normal)

83273357 182584578 5 (cancer+normal vs cancer+normal)

4- 1- cg0196865

cgl7337917 (normal vs normal) (cancer vs cancer)

96102203 237207256 7

5- cg2208047

cg26545167 (normal vs normal) 1-28176762 (cancer vs cancer)

106606747 2

(cancer vs cancer)

5- 10- cg0852926

cg26927150 (normal vs normal) (cancer+normal vs

137523911 100994381 0

cancer+normal)

5- 10- cgl926268

cgl8924771 (normal vs normal) (cancer vs cancer)

166582591 132284252 3

5- 10- cg0449285 (cancer vs cancer) cg09739850 (normal vs normal)

175545977 133558786 8 (cancer vs cancer)

5- 10- cg2056849

cgl8689929 (normal vs normal) (cancer vs cancer)

34005493 133558893 7

5- 10- cg2346070 (cancer vs cancer) cgl8774611 (normal vs normal)

94623660 133558971 7 (cancer vs cancer)

6- 10- cgl733950

cg25407410 (normal vs normal) (cancer vs cancer)

143891975 43572621 5

6- cgl848584

cg25641223 (normal vs normal) 11-2291652 (cancer vs cancer)

165747945 4

6-1836850 cg21478123 (normal vs normal) 11-2291677 cg2234612 (cancer vs cancer) 4

(cancer vs cancer)

6- 11- cg0901717

cgl3598232 (normal vs normal) (cancer+normal vs

33284748 35440525 4

cancer+normal)

7- 11- cg2698566

cg26502514 (normal vs normal) (cancer vs cancer)

134916876 35441088 6

(cancer vs cancer)

7- 11- cgl638652

cg22807241 (normal vs normal) (cancer+normal vs

147709862 49974622 3

cancer+normal)

7- 11- cg2166799

cg24249450 (normal vs normal) (cancer vs cancer)

33894296 55593465 8

7- cgl406777

cg26347222 (normal vs normal) 11-615950 (cancer vs cancer)

33945948 0

(cancer vs cancer)

7- cgl337828

cgl5331578 (normal vs normal) 11-616089 (cancer+normal vs

34193859 4

cancer+normal)

7- 12- cg0833077

cg22296322 (normal vs normal) (cancer vs cancer)

56517941 115122028 8

7- 12- cg2279773

cg24791283 (normal vs normal) (cancer vs cancer)

98945891 115122157 5

8- 12- cg0049947

cg21484512 (normal vs normal) (cancer vs cancer)

11189650 115122304 5

8- 12- cg0630046

cg22335954 (normal vs normal) (cancer vs cancer)

121166405 125383138 9

8- 12- cgl465772

cgl8842396 (normal vs normal) (cancer vs cancer)

139750054 130498701 8

(cancer vs cancer) (cancer vs cancer)

8- cg0680796

cgl8760194 (normal vs normal) 12-4274034 (normal vs normal)

35186363 6

(cancer+normal vs cancer+normal)

(cancer vs cancer)

8- cg0887391

cgl7217741 (normal vs normal) 12-4274070 (cancer+normal vs

56788346 2

cancer+normal)

COAD READ (cancer 12- cg2008007

(cancer vs cancer) vs cancer) 85430174 9

12- cg2634597

Status - Hyper (cancer vs cancer)

85430215 1

(cancer vs cancer) (cancer vs cancer)

1- 13- cgl615886

cg02905065 (cancer+normal vs (cancer+normal vs

120837955 32605218 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 13- cg2221925

cg07784526 (cancer+normal vs (normal vs normal)

120838320 32605406 4

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 13- cgl694165

cgl8948743 (cancer+normal vs (normal vs normal)

120838323 32605611 6

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

1- 13- cgl849568

cg22710840 (cancer+normal vs (cancer vs cancer)

143913552 42032666 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 14- cg2303481

cgl 1207983 (cancer+normal vs (normal vs normal)

150254477 105714589 8

cancer+normal) (cancer+normal vs cancer+normal)

1- (cancer vs cancer) 14- cgl547436 (cancer vs cancer) cg06982544

150254546 (cancer+normal vs 105714833 7 (cancer vs cancer) cancer+normal) (normal vs normal)

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 14- cgl656154

cgl0055771 (cancer+normal vs (normal vs normal)

150254869 105714843 3

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 14- cg0123756

cgl8031008 (cancer+normal vs (normal vs normal)

150266311 105715025 5

cancer+normal) (cancer+normal vs cancer+normal)

1- 14- cg2296893 (cancer vs cancer) cg00552973 (cancer vs cancer)

206137054 37131555 6 (cancer vs cancer)

10- 14- cgl903206

cgl3692476 (cancer vs cancer) (cancer vs cancer)

101088828 37131601 6

(cancer vs cancer) (cancer vs cancer)

10- 14- cg2643569

cg00197495 (cancer+normal vs (cancer+normal vs

93392836 38057752 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 14- cgl851587

cgl2486537 (cancer+normal vs (cancer+normal vs

93393030 72943461 2

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 14- cg2474931

cg26963029 (cancer+normal vs (cancer vs cancer)

94473668 84173031 1

cancer+normal)

(cancer vs cancer)

11- 15- cg0243043 (cancer vs cancer) cgl 1117364 (cancer+normal vs

94501718 74532450 0 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- cgl642709 (normal vs normal) cg23628232 (cancer+normal vs 16-1202468

94502388 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

11- cg0060996 (cancer vs cancer) cg20493960 (cancer+normal vs 16-1202819

94502524 6 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

12- 16- cg2729964

cg24979348 (cancer vs cancer) (cancer+normal vs

15374303 86231823 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 16- cg0798922

cg25283609 (cancer vs cancer) (normal vs normal)

15374457 86231948 1

(cancer+normal vs cancer+normal)

(cancer vs cancer)

12- 16- cg0728205

cgl5611413 (cancer+normal vs (cancer vs cancer)

54333587 86232315 8

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 16- cg2682798

cg21161136 (cancer+normal vs (cancer+normal vs

54519825 86232457 7

cancer+normal) cancer+normal)

(cancer vs cancer)

12- 16- cg0892714

cgl 1654179 (cancer vs cancer) (cancer+normal vs

57998762 86321899 5

cancer+normal)

(cancer vs cancer)

13- 16- _C g0404441

cg20193324 (cancer+normal vs (cancer vs cancer)

26626134 89789362 8

cancer+normal)

13- (cancer vs cancer) 17- cg2676336 (cancer vs cancer) cg25264081

95620306 (cancer vs cancer) 18266135 2 (cancer vs cancer)

(cancer vs cancer)

15- 17- cgl620613

cg05280133 (cancer+normal vs (cancer vs cancer)

45670068 47210270 8

cancer+normal) (cancer vs cancer)

15- cgl508611

cgl 1431346 (cancer+normal vs 19-1766358 (cancer vs cancer)

45670478 3

cancer+normal)

(cancer vs cancer)

15- cg2287425

cgOl 145430 (cancer+normal vs 19-1768630 (cancer vs cancer)

45670526 5

cancer+normal)

16- 19- cg2043903

cg09239744 (cancer vs cancer) (cancer vs cancer)

10276580 34359847 0

16- cgl472595

cg03210180 (cancer vs cancer) 19-5294093 (cancer vs cancer)

15528758 2

16- 19- cg2054219

cg04462627 (cancer vs cancer) (cancer vs cancer)

58019123 54850619 0

(cancer vs cancer)

(cancer vs cancer)

17- 2- cg0137682 (cancer vs cancer) cg22588307 (cancer+normal vs

33775394 102804405 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- 2- cg0067489 (cancer vs cancer) cg06740897 (cancer+normal vs

46124821 102804576 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

2- cgl512576 (cancer vs cancer)

17-881949 cg23513567 (cancer+normal vs

215275838 3 (cancer vs cancer) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cg0658041

17-882342 cgl3966567 (cancer+normal vs (cancer+normal vs

215276156 9

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- (normal vs normal) 2- cg0513745

cg09479389 (cancer+normal vs

14016729 (cancer+normal vs 233368263 0

cancer+normal) cancer+normal)

19- 20- cg2458132

cgl5823845 (cancer vs cancer) (cancer vs cancer)

3869172 55204266 6

(cancer vs cancer)

19- 20- cgl969420

cgl6733654 (cancer+normal vs (cancer vs cancer)

5293083 55204351 0

cancer+normal)

(cancer vs cancer)

19- 20- cgl252135

cg00846300 (cancer+normal vs (cancer vs cancer)

57831632 55204593 3

cancer+normal)

19- 20- cg0501306

cgl9533530 (cancer vs cancer) (cancer vs cancer)

57831662 55204633 4

(cancer vs cancer)

19- 20- cg2673654

cg23986470 (cancer+normal vs (cancer vs cancer)

57831678 55204986 0

cancer+normal)

19- 21- cgl932027

cgl4786398 (cancer vs cancer) (cancer vs cancer)

57831816 47063408 5

19- 3- cg0780291

cg01325460 (cancer vs cancer) (cancer vs cancer)

57831819 123603311 7

19- 3- cg2714324

cgl7849956 (cancer vs cancer) (cancer vs cancer)

57862480 169489583 6

(cancer vs cancer)

19- 4- cgl482792

cgl3788592 (cancer vs cancer) (cancer+normal vs

57862612 187002617 9

cancer+normal)

(cancer vs cancer)

19- cg0857620

cgl6848116 (cancer+normal vs 4-4858059 (cancer vs cancer)

57862627 8

cancer+normal)

(cancer vs cancer)

19- cg0668832

cg21627760 (cancer+normal vs 4-4858340 (cancer vs cancer)

57862638 3

cancer+normal)

(cancer vs cancer)

19- cgl333253

cg07494047 (cancer+normal vs 4-4858482 (cancer vs cancer)

57862713 8

cancer+normal) (cancer vs cancer)

2- cg0560035 (cancer vs cancer) cg23977631 (cancer+normal vs 4-4858598

100938799 0 (cancer vs cancer) cancer+normal)

2- cg0318918

cgl4997226 (cancer vs cancer) 4-4858752 (cancer vs cancer)

100938813 4

(cancer vs cancer)

2- (cancer vs cancer) cgl 128122

cg09667303 4-60001000 (cancer+normal vs

144695257 (cancer vs cancer) 4

cancer+normal)

(cancer vs cancer)

2- (normal vs normal) 5- cgl299580

cgl 8061904 (cancer vs cancer)

158454110 (cancer+normal vs 151304312 0

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl015482

cg21972382 6-17600994 (cancer vs cancer)

29339076 (cancer+normal vs 6

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cg2410961

cg05038216 6-19838817 (cancer vs cancer)

29339091 (cancer+normal vs 2

cancer+normal)

(cancer vs cancer)

2- 7- cg2666365

cg02764245 (cancer+normal vs (cancer vs cancer)

66803033 139167960 1

cancer+normal)

20- 7- cg0852882

cg24562819 (cancer vs cancer) (cancer vs cancer)

23029806 139168305 6

(cancer vs cancer)

20- (cancer vs cancer) 7- cg2495625 (cancer vs cancer) cg09279949

23030250 (cancer vs cancer) 139168481 0 (cancer+normal vs cancer+normal)

20- 7- cgl550615 (cancer vs cancer) cg25397597 (cancer vs cancer)

23030442 139168484 7 (normal vs normal)

(cancer vs cancer)

20- 7- cg0091901

cg22152407 (cancer+normal vs (cancer vs cancer)

23030446 139168487 6

cancer+normal)

(cancer vs cancer)

20- 7- cg0069993

cgl0185099 (cancer vs cancer) (cancer+normal vs

23031246 139168503 4

cancer+normal)

(cancer vs cancer)

20- 7- cg0522419

cgl3516746 (cancer+normal vs (cancer vs cancer)

3389408 139168523 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

20- 7- cg2518150 (normal vs normal) cg20681068 (cancer+normal vs

3389535 139168659 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

20- 7- cgl010837

cgl6919517 (cancer vs cancer) (cancer+normal vs 61050914 156811362 2

cancer+normal)

(cancer vs cancer)

20- 7- cg0959520 (cancer vs cancer) cg08568720 (cancer vs cancer)

61051432 156812104 2 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

22- 7- cg0257007

cgl5471953 (cancer vs cancer) (normal vs normal)

44258572 156814845 9

(cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- 7- cg2023565

cgl5511738 (cancer+normal vs (cancer+normal vs

48700027 156815030 8

cancer+normal) cancer+normal)

4- (cancer vs cancer) 7- cg2221615

cgl9602081 (cancer vs cancer)

111553161 (cancer+normal vs 157643037 7 cancer+normal)

4- cgl654495

cg24291087 (cancer vs cancer) 7-20825634 (cancer vs cancer)

30722781 6

4- (cancer vs cancer) cg0206768 (cancer vs cancer) cg00989765 7-25894793

55991860 (cancer vs cancer) 8 (cancer vs cancer)

5- cg2183372

cgl3648501 (cancer vs cancer) 7-56553285 (cancer vs cancer)

142785258 8

(cancer vs cancer)

5- cg09528265 (cancer+normal vs Status - Hypo

146258195

cancer+normal)

5- cg0182413

cgl 1826826 (cancer vs cancer) 1-10699604 (cancer vs cancer)

146258237 8

5- cgl386376 (cancer vs cancer) cg25149751 (cancer vs cancer) 1-11561908

146258427 4 (cancer vs cancer)

(cancer vs cancer)

5- cgl389767 (cancer vs cancer) cg26880493 (cancer+normal vs 1-1374310

31855185 5 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

5- cgl963947 (cancer vs cancer) cg08392199 (cancer+normal vs 1-1374669

38556223 9 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- 1- cg2440877 (cancer vs cancer) cgl2587766 (cancer+normal vs

38556435 203098067 6 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

5- cg2457922

cgl8174928 (cancer+normal vs 1-2205902 (cancer vs cancer)

38557085 4

cancer+normal)

(cancer vs cancer)

5- cg0702140

cg03723506 (cancer+normal vs 1-8292657 (cancer vs cancer)

38557143 5

cancer+normal)

5- 10- cg0386003

cgl2602374 (cancer vs cancer) (cancer vs cancer)

38557162 134231517 8

5- 10- cg0613909 (cancer vs cancer) cgl8848688 (cancer vs cancer)

38557386 134499505 9 (cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer)

5- 10- cg0045845 (cancer vs cancer) cgl7528648 (cancer+normal vs

38846100 134499528 4 (cancer+normal vs

cancer+normal)

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl344114

cgl0039188 (cancer+normal vs (cancer vs cancer)

72130209 134499734 2

cancer+normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 10- cg0254112 (cancer vs cancer) cg25210451 (cancer+normal vs

72130407 134499752 5 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl521607

cgl5045441 (cancer+normal vs (cancer+normal vs

72130432 134567188 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cg0063265

cg26162616 (cancer+normal vs (cancer+normal vs

72130539 27703336 7

cancer+normal) cancer+normal)

(cancer vs cancer)

6- 10- cg0886655 (cancer vs cancer) cg22300282 (cancer+normal vs

72130553 49647167 7 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

6- cg2631178

cg25141674 (cancer+normal vs 10-712032 (cancer vs cancer)

72130689 2

cancer+normal)

6- 11- cgl208747 (cancer vs cancer) cg24772267 (cancer vs cancer)

72130742 46374124 1 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 11- cg0616816 (cancer vs cancer) cg00920327 (cancer+normal vs

72130755 47372949 6 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- 11- cgl035413 (cancer vs cancer) cg23778596 (cancer+normal vs

149411498 47372960 4 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

7- 12- cg0771917

cg08131100 (cancer+normal vs (cancer vs cancer)

149411652 109889431 2

cancer+normal)

(cancer vs cancer)

7- 12- cg2682910

cg03788131 (cancer+normal vs (cancer vs cancer)

149412290 119592094 1

cancer+normal)

8- 12- cg0235304

cg03192020 (cancer vs cancer) (cancer vs cancer)

11204681 124718401 8

8- 12- cg2484736

cgl3165109 (cancer vs cancer) (cancer vs cancer)

11205155 125034283 6

8- 12- cg2513071

cg05362548 (cancer vs cancer) (cancer vs cancer)

11205166 133159752 0

8- 13- cgl373180 (cancer vs cancer) cgl4900984 (cancer vs cancer)

11205247 101167901 0 (cancer vs cancer)

8- 13- cg2054907

cg05746795 (cancer vs cancer) (cancer vs cancer)

48100410 111330434 9

(cancer vs cancer) (cancer vs cancer)

9- 14- cgl497793

cgl4632002 (cancer+normal vs (cancer+normal vs

124132393 104190829 8

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

9- 14- cg0152347

cgl4654324 (cancer+normal vs (cancer vs cancer)

137299436 45365651 4

cancer+normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(normal vs normal) 14- cg2313860 (cancer vs cancer)

9-707166 cgl4399863

(cancer+normal vs 91770145 8 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

14- cgl946560 (cancer vs cancer)

9-707387 cgl3877502 (normal vs normal)

91770229 5 (cancer vs cancer) (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (normal vs normal) 15- cgl 148472

9-707410 cg03358592 (cancer+normal vs

(cancer+normal vs 102157726 1

cancer+normal) cancer+normal)

15- cg2344101 (cancer vs cancer)

Status - Hypo

34657364 8 (cancer vs cancer)

(normal vs normal)

(normal vs normal) (cancer vs cancer)

16- cg0931979 (cancer vs cancer)

1-1095607 cg02971920 (cancer vs cancer)

12061715 7 (cancer+normal vs (cancer+normal vs

cancer+normal) cancer+normal)

(normal vs normal)

1- (cancer vs cancer) cg0530879 (cancer vs cancer) cg06665322 16-1578807

167059365 (cancer+normal vs 2 (cancer vs cancer) cancer+normal)

(normal vs normal)

(cancer vs cancer)

1- (cancer vs cancer) cg0855586

cg24600987 16-3345604 (cancer+normal vs

17898874 (cancer vs cancer) 6

cancer+normal) (cancer+normal vs cancer+normal)

16- cg0300186

1-2003605 cg22332339 (cancer vs cancer) (cancer vs cancer)

47047897 7

(cancer vs cancer) (cancer vs cancer)

1- 16- cg0374367

cgl3487476 (cancer+normal vs (cancer+normal vs

206593025 47048004 8

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 16- cg2672407

cg05230389 (cancer+normal vs (cancer vs cancer)

220132091 50707467 0

cancer+normal)

(cancer vs cancer)

1- 16- cg0253522

cgl0576232 (cancer+normal vs (cancer vs cancer)

220132097 77952576 3

cancer+normal)

(cancer vs cancer)

1- 16- cg0088833

cg01554316 (cancer+normal vs (cancer vs cancer)

230257067 80654763 6

cancer+normal)

(cancer vs cancer)

1- (cancer vs cancer) 16- cgl019572

cg22537280 (cancer vs cancer)

54723213 (cancer+normal vs 88538355 6

cancer+normal)

(cancer vs cancer)

1- 16- cgl662735

cg00838829 (cancer vs cancer) (cancer+normal vs

54723426 88540175 8

cancer+normal)

16- cg0894016

1-9339683 cg20700740 (cancer vs cancer) (cancer vs cancer)

88540241 9

(cancer vs cancer)

(cancer vs cancer) 16- cg0501267

10-518370 cg26718707 (cancer vs cancer)

(cancer+normal vs 88564366 6

cancer+normal)

11- 16- cg2718379

cg09112054 (cancer vs cancer) (cancer vs cancer)

119609303 89381904 1

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

11- 17- cg0878325

cgl 1069338 (cancer vs cancer) (cancer+normal vs

130060459 40996565 3

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) 17- cgl 167967

cgl4907310 (cancer vs cancer)

2287734 (cancer+normal vs 55015826 3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 17- cgl717276

cgl7373759 (cancer+normal vs (cancer+normal vs

76265321 62120439 1

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) 17- cgl979087

cg24256772 (cancer+normal vs

94275751 (cancer vs cancer) 77948884 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 18- cg0368211

cg24961970 (cancer+normal vs (cancer+normal vs

109885015 77623598 2

cancer+normal) cancer+normal)

(cancer vs cancer)

12- 19- cg2004233

cg02419362 (cancer+normal vs (cancer vs cancer)

121203948 17444421 8

cancer+normal)

(normal vs normal)

12- 19- cgl405565

cgl8754342 (cancer vs cancer) (cancer vs cancer)

14849268 50117794 5

(cancer vs cancer)

12- 19- cg0887394 (cancer vs cancer) cg21235960 (cancer vs cancer)

50476169 51607432 0 (cancer vs cancer)

(cancer vs cancer)

13- 2- cg2474666

cgl9524009 (cancer+normal vs (cancer vs cancer)

52735075 201342647 6

cancer+normal)

16- (cancer vs cancer) 2- cg0810730

cg05028274 (cancer vs cancer)

71755733 (cancer+normal vs 240234604 8 cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

16- 2- cg0400387 (cancer vs cancer) cg07747924 (cancer+normal vs

78233495 241290895 1 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

(cancer vs cancer)

16- cgl586551

cgl0398761 (cancer vs cancer) 2-43252424 (cancer vs cancer)

89169289 1

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cgl365050

cg23346781 2-692026 (cancer vs cancer) 1412449 (cancer+normal vs 4

cancer+normal)

(normal vs normal) (cancer vs cancer)

17- cg0818297

cg07704981 (cancer vs cancer) 2-7164527 (cancer vs cancer)

26127537 5

(cancer+normal vs cancer+normal)

(normal vs normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) cg2099575

cgl 1542336 2-7164586 (cancer vs cancer)

4042717 (cancer+normal vs J

(cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

17- cg0023076 (cancer vs cancer) cg06909248 (cancer vs cancer) 2-9388337

70256462 6 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 22- cg0789565

cg21088108 (cancer+normal vs (cancer vs cancer)

77075025 50616420 7

cancer+normal)

(normal vs normal)

17- (cancer vs cancer) 3- cgl053238

cg22462714 (cancer vs cancer)

79224306 (cancer+normal vs 141161876 4

cancer+normal)

(normal vs normal) (normal vs normal) (cancer vs cancer) (cancer vs cancer)

17- 3- cg2193737

cgl6366685 (cancer vs cancer) (cancer vs cancer)

80535398 194868750 7

(cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- 3- cgl630687

cg03454705 (cancer vs cancer) (cancer vs cancer)

80535428 194868790 0

(cancer+normal vs

cancer+normal)

(normal vs normal)

18- (cancer vs cancer) cg2102856

cg00137385 3-50287909 (cancer vs cancer)

46288005 (cancer+normal vs 2

cancer+normal)

(cancer vs cancer)

19- cgl755330

cgl7741192 (cancer+normal vs 3-55508460 (cancer vs cancer) 2811654 0

cancer+normal)

(normal vs normal)

(cancer vs cancer)

19- cgl070125

cgl2028674 (cancer vs cancer) 3-55508585 (cancer vs cancer)

39306244 2

(cancer+normal vs

cancer+normal)

19- cg0631186 (cancer vs cancer) cg01983454 (cancer vs cancer) 3-55508686

4174165 3 (cancer vs cancer)

2- cg24419520 (normal vs normal) 3-55517101 cg0358899 (cancer vs cancer) 106959257 (cancer vs cancer) 8

(cancer vs cancer)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- cgl3656404 cg2757105 (cancer vs cancer)

(cancer+normal vs 4-1646179

106959384 7

cancer+normal) (cancer+normal vs cancer+normal)

2- cg00049868 cg2497923

(cancer vs cancer) 4-1800284

11245407 (cancer vs cancer)

3

(cancer vs cancer)

2- (cancer vs cancer)

cg25890678 cg2368847 (cancer vs cancer)

5-42756851

112808038 (cancer vs cancer) 9 (cancer+normal vs cancer+normal)

2- (cancer vs cancer) cgl0142874 cgl258592

(cancer vs cancer) 5-42756876

11917623 (cancer+normal vs

3

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

2- cgl2793924 (cancer vs cancer) 5-42757171 cg2192956

17830624 (cancer+normal vs

4

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer)

cg03426602 cg0008160

5-72922957

227312417 (cancer vs cancer)

(cancer+normal vs 2

cancer+normal)

(cancer vs cancer)

2- cgl8313132 cg0265236

(cancer+normal vs 6-31111076

234526077 (cancer vs cancer)

9

cancer+normal)

2- cgl 9286774 cg0313096

(cancer vs cancer) 6-31111088

240181931 (cancer vs cancer)

2

(normal vs normal)

2- (cancer vs cancer)

cg00529371 cgl688707

6-3324467

242735324 (cancer vs cancer)

(cancer+normal vs 0

cancer+normal)

2- cg21913376 (cancer vs cancer) cgl911707

6-3723112

55366440 (cancer vs cancer)

0

(normal vs normal)

(cancer vs cancer)

2-8850020 cg00240378 7- cg0811671

(cancer vs cancer) (cancer vs cancer)

101596218 1

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

2- cgl 1464842 7- cg2326144

(cancer vs cancer)

97427975 (cancer vs cancer)

101596340 3

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

20- cg25225756 7- cg2719567

(cancer vs cancer)

55959405 (cancer vs cancer)

101943788 6

(cancer+normal vs

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- (cancer vs cancer)

cg22618720 cg2093409 (cancer vs cancer)

7-1117418

55959549 (cancer+normal vs 6 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

21- cg24168308 cg0813708 (cancer vs cancer)

(cancer+normal vs 7-1117540

27372387 5 (cancer+normal vs cancer+normal)

cancer+normal)

21- cgl 1321156 (cancer vs cancer) 7-1970923 cg2418991 (cancer vs cancer) 27372396 (cancer+normal vs 7

cancer+normal)

(cancer vs cancer)

21- cgl345749 (cancer vs cancer) cg23269692 (cancer+normal vs 7-2609648

27372446 6 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

21- cg0915945

cgl 8274664 (cancer+normal vs 7-2609861 (cancer vs cancer)

27372461 2

cancer+normal)

(cancer vs cancer)

21- cg2338164

cg05957544 (cancer+normal vs 7-44187310 (cancer vs cancer)

45360804 6

cancer+normal)

(cancer vs cancer)

21- cgl330193 (cancer vs cancer) cg08823554 (cancer+normal vs 7-44526856

46269191 1 (cancer vs cancer) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

22- (cancer vs cancer) cg0611460 (cancer vs cancer) cg01274916 7-4806755

31062286 (cancer+normal vs 5 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) cg2533026 (cancer vs cancer) cg27024386 (cancer vs cancer) 7-4806949

150238208 4 (cancer+normal vs cancer+normal)

(cancer vs cancer) (normal vs normal)

3- (cancer vs cancer) cg2288454 (cancer vs cancer) cg02504622 7-97841864

150238257 (cancer+normal vs 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- (cancer vs cancer) cgl892981 (cancer vs cancer) cg09433558 7-97875293

171412917 (cancer+normal vs 4 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- cgl856389 (cancer vs cancer) cg24158324 (cancer+normal vs 7-97875333

55525967 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

8- cgl463127

3-9820588 cgl5771477 (cancer+normal vs (cancer vs cancer)

145163102 6

cancer+normal)

(cancer vs cancer)

4- cg0401147

cgl2710519 (cancer+normal vs 8-22079330 (cancer vs cancer)

144275126 0

cancer+normal)

(cancer vs cancer)

4- cgl988865

cg00268149 (cancer+normal vs 8-28929168 (cancer vs cancer)

184017790 4

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

4- cg0927218

cg23442198 (cancer vs cancer) 8-30334348 (cancer+normal vs

187126114 6

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

4- cg0307823

cg21399040 (cancer vs cancer) 8-9040449 (cancer vs cancer)

187629328 9

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

4- (cancer+normal vs

cg24820270 (cancer vs cancer)

187629336 cancer+normal)

(cancer+normal vs

cancer+normal)

(normal vs normal)

4- cgO 1040779 (cancer vs cancer) Status - Hyper

187629339

(cancer+normal vs cancer+normal)

(normal vs normal)

(cancer vs cancer)

4- cgl331461 (cancer+normal vs cg25352342 (cancer vs cancer) 1-12655992

187629387 4 cancer+normal)

(cancer+normal vs

cancer+normal)

(normal vs normal)

(normal vs normal)

4- (cancer vs cancer) cg0433983

cg24833566 1-12656114 (cancer+normal vs

187629400 (cancer+normal vs 7

cancer+normal) cancer+normal)

(normal vs normal)

4- (cancer vs cancer) cg0951787 (cancer+normal vs cgl3454542 1-12656315

187629427 (cancer+normal vs 3 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 1- cg2239343 (cancer+normal vs

4-6945702 cg05069807

(cancer+normal vs 168489851 6 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

cg0677230 (cancer+normal vs

4-6945745 cgl6574807 (cancer vs cancer) 1-17571896

9 cancer+normal) (cancer+normal vs

cancer+normal)

(normal vs normal) (cancer vs cancer) (cancer vs cancer) 1- cg0015385 (cancer vs cancer)

4-7985238 cgl7630294

(cancer+normal vs 182584341 6 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

4- 1- cg0714429 (normal vs normal) cg02008770 (cancer+normal vs

99668618 182584520 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- (cancer vs cancer) 1- cg2408589 (normal vs normal) cg26531174

149546073 (cancer+normal vs 182584578 5 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) 1- cgl839120 (cancer+normal vs cg09690765

149547566 (cancer+normal vs 223747670 9 cancer+normal) cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) cg0408053 (cancer+normal vs cg26722544 1-2886868

179393917 (cancer+normal vs 0 cancer+normal) cancer+normal)

6- cg2560577 (cancer+normal vs cgl 1114242 (cancer vs cancer) 1-44466601

136756541 1 cancer+normal)

6- cg0001416 (cancer+normal vs cg06093525 (cancer vs cancer) 1-6511878

136874706 8 cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cg0852926

cgO 1086672 (cancer vs cancer) (cancer+normal vs

31123044 100994381 0

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

7- 10- cg0850533 (cancer+normal vs cgl7677524 (cancer vs cancer)

150069026 28342666 5 cancer+normal)

(cancer+normal vs

cancer+normal)

(normal vs normal)

7- (cancer vs cancer) 11- cgl090497 (cancer+normal vs cgl2613107

150069577 (cancer+normal vs 119227328 2 cancer+normal) cancer+normal) (cancer vs cancer) (normal vs normal)

7- 11- cg0343227

cg00835828 (cancer+normal vs (cancer+normal vs

150069890 119612342 5

cancer+normal) cancer+normal)

(normal vs normal)

11- cg0919436

7-1563610 cgl6784174 (cancer vs cancer) (cancer+normal vs

119612475 4

cancer+normal)

(normal vs normal)

7- 11- cg2042991

cg26712096 (cancer vs cancer) (cancer+normal vs

24798855 18416535 1

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 11- cgl638652

cg08085853 (cancer+normal vs (cancer+normal vs

33793736 49974622 3

cancer+normal) cancer+normal)

7- 11- cgl706096 (cancer+normal vs cgl0349880 (cancer vs cancer)

50133100 55796572 4 cancer+normal)

7- (cancer vs cancer) cgl654103 (cancer+normal vs cg09921682 11-615519

50133131 (cancer vs cancer) 1 cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

7- cgl813153

cgl6233515 (cancer vs cancer) 11-615732 (cancer+normal vs

73408058 7

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

7- cg0765235 (cancer+normal vs cg07243141 (cancer vs cancer) 11-616009

73408060 0 cancer+normal)

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

7- cgl337828

cgl8780627 (cancer vs cancer) 11-616089 (cancer+normal vs

73408101 4

(cancer+normal vs cancer+normal) cancer+normal)

8- 12- cgl 173794 (cancer+normal vs cgl0454596 (cancer vs cancer)

140971959 130450777 1 cancer+normal)

(cancer vs cancer)

8- 12- cg0157702 (cancer+normal vs

_C gl4494313 (cancer+normal vs

18248453 133000830 9 cancer+normal) cancer+normal)

(normal vs normal)

9- (cancer vs cancer) 12- cg2188203 (cancer+normal vs cgl 3847724

126243651 (cancer+normal vs 31769252 7 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

9- cg0680796

cgl 1557901 (cancer vs cancer) 12-4274034 (normal vs normal)

128022358 6

(cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- cg0887391

cgl3601936 (cancer+normal vs 12-4274070 (cancer+normal vs

140198751 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 13- cgl615886

cgl3710613 (cancer+normal vs (cancer+normal vs

140574551 32605218 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

(cancer+normal vs 13- cg2221925

(normal vs normal) cancer+normal) 32605406 4

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- cgl694165

Status - Hyper (normal vs normal)

32605611 6

(cancer+normal vs cancer+normal) (cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 14- cg2303481

cg02905065 (cancer+normal vs (normal vs normal)

120837955 105714589 8

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 14- cgl547436

cg07784526 (cancer+normal vs (normal vs normal)

120838320 105714833 7

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 14- cgl656154

cgl8948743 (cancer+normal vs (normal vs normal)

120838323 105714843 3

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 14- cg0123756

cg22710840 (cancer+normal vs (normal vs normal)

143913552 105715025 5

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 14- cg2643569

cgl 1207983 (cancer+normal vs (cancer+normal vs

150254477 38057752 8

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 14- cgl016872 (cancer+normal vs cg06982544 (cancer+normal vs

150254546 38068608 2 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

1- 14- cg0479116

cgl0055771 (cancer+normal vs (cancer+normal vs

150254869 62331287 2

cancer+normal) cancer+normal)

1- (cancer+normal vs 15- cgl342942 (cancer+normal vs cgO 1566242

150266242 cancer+normal) 22798849 4 cancer+normal)

(cancer vs cancer)

1- 15- cgl 198357 (cancer+normal vs cgl8031008 (cancer+normal vs

150266311 53090807 6 cancer+normal) cancer+normal)

(normal vs normal)

1- (cancer+normal vs 15- cg2248874

cg26535484 (cancer+normal vs

150266313 cancer+normal) 53096763 5

cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs cgl642709 (normal vs normal) cg08293086 16-1202468

150266477 cancer+normal) 6 (cancer+normal vs cancer+normal)

1- (cancer+normal vs 16- cg0241708 (cancer+normal vs cg23819679

150266488 cancer+normal) 51183533 4 cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 16- cg2729964

cg09808343 (cancer+normal vs

150266643 cancer+normal) 86231823 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- (cancer+normal vs 16- cg0798922

cgl5934674 (normal vs normal)

150266645 cancer+normal) 86231948 1

(cancer+normal vs cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 16- cg2682798

cgl5389528 (cancer+normal vs

210111028 cancer+normal) 86232457 7

cancer+normal)

(cancer vs cancer)

10- 16- cg2677863 (cancer+normal vs cg00197495 (cancer+normal vs

93392836 86331580 0 cancer+normal) cancer+normal)

(cancer vs cancer)

10- 17- cg0881786 (cancer+normal vs cgl2486537 (cancer+normal vs

93393030 19656554 7 cancer+normal) cancer+normal)

11- cg01234063 (normal vs normal) 17- cgl l96113 (cancer+normal vs 126226007 (cancer+normal vs 38599366 8 cancer+normal) cancer+normal)

(cancer vs cancer)

11- cg26963029 17- cgl 164020 (cancer+normal vs

94473668 (cancer+normal vs

42857157

cancer+normal) 8 cancer+normal)

(cancer vs cancer)

11- cgl 1117364 cgl469434 er+normal vs

94501718 (cancer+normal vs 19-5828172 (canc

2

cancer+normal) cancer+normal)

(cancer vs cancer)

11- cg23628232 cg0991152

(cancer+normal vs 19-5828301 (cancer+normal vs

94502388 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 2- cg20493960 cg0137682 (cancer vs cancer)

94502524 (cancer+normal vs

102804405 9

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 2- cgl5611413 cg0067489 (cancer vs cancer)

54333587 (cancer+normal vs

102804576 6

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cg21161136 2- cg0658041

54519825 (cancer+normal vs

215276156 (cancer+normal vs

9

cancer+normal) cancer+normal)

12- (normal vs normal) (cancer vs cancer)

2- cg22524951 cg0513745

91775247 (cancer+normal vs

233368263 (cancer+normal vs

0

cancer+normal) cancer+normal)

(normal vs normal)

12- cg24338491 cg0970391

(cancer+normal vs 2-56236435 (cancer+normal vs

91775501 0

cancer+normal) cancer+normal)

(cancer vs cancer)

13- cg20193324 cg2560253

(cancer+normal vs 2-8816608 (cancer+normal vs

26626134 6

cancer+normal) cancer+normal)

13- (cancer+normal vs

cg22138327 cg2194600

2-8817010 (cancer+normal vs

27999177 cancer+normal) 6 cancer+normal)

(normal vs normal)

14- cg01655898 cg0332559

(cancer+normal vs 3-12994877 (cancer+normal vs

21439243 8

cancer+normal) cancer+normal)

(cancer vs cancer)

15- (normal vs normal) cg05280133 cgl370789

45670068 (cancer+normal vs 3-27674461

4 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

15- (normal vs normal) cgl 1431346 cgl 128215

45670478 (cancer+normal vs 3-63428840 (cancer+normal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer)

15- cgOl 145430 cg0846212

(cancer+normal vs 4-1160783 (cancer+normal vs

45670526 2

cancer+normal) cancer+normal)

15- (cancer+normal vs

cg07109804 cg2275739 (cancer+normal vs

83654517 4-1166270

cancer+normal) 1 cancer+normal)

15- (cancer+normal vs

cg01323954 cgl815963

4-1166272 (cancer+normal vs

83654524 cancer+normal) 6 cancer+normal)

15- (cancer+normal vs 4- cgl9707853 cgl518979 (cancer+normal vs

98197914 cancer+normal) 174456504 3 cancer+normal)

(cancer vs cancer)

17- 4- (normal vs normal) cg22588307 cg0108456

33775394 (cancer+normal vs

175444482 (cancer+normal vs

6

cancer+normal) cancer+normal)

17- (cancer vs cancer)

(cancer+normal vs 4- cg24526433 cgl482792

37794080 cancer+normal) 187002617 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cg06740897 cgl 128122

46124821 (cancer+normal vs 4-60001000 (cancer+normal vs

4

cancer+normal) cancer+normal)

17-881949 cg23513567 (cancer vs cancer) 4-84869222 cg2150116 (cancer+normal vs (cancer+normal vs 7 cancer+normal) cancer+normal)

(cancer vs cancer)

cgl957684 (cancer+normal vs

17-882342 cgl3966567 (cancer+normal vs 5-11385893

3 cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

19- (normal vs normal) cg2408212

cg09479389 5-672872 (cancer+normal vs

14016729 (cancer+normal vs 1

cancer+normal) cancer+normal)

19- (cancer+normal vs cg2325668 (cancer+normal vs cg23044017 5-75996951

36822442 cancer+normal) 3 cancer+normal)

19- (cancer+normal vs 6- cgl840433 (cancer+normal vs cg21808240

36822564 cancer+normal) 166869078 5 cancer+normal)

(cancer vs cancer)

19- 6- cg0405046 (cancer+normal vs cgl6733654 (cancer+normal vs

5293083 170602486 3 cancer+normal) cancer+normal)

19- (cancer+normal vs 6- cg2644600 (cancer+normal vs cgl7412580

57792200 cancer+normal) 170604454 9 cancer+normal)

(cancer vs cancer)

19- cg0883405 (cancer+normal vs cg00846300 (cancer+normal vs 6-43022109

57831632 0 cancer+normal) cancer+normal)

(cancer vs cancer)

19- 7- cg0977763 (cancer+normal vs cg23986470 (cancer+normal vs

57831678 123674510 7 cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer+normal vs 7- cg2495625 (cancer vs cancer)

_C g04174410

57832339 cancer+normal) 139168481 0 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 7- cg0069993

cgl6848116 (cancer+normal vs (cancer+normal vs

57862627 139168503 4

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- 7- cg2518150 (normal vs normal) cg21627760 (cancer+normal vs

57862638 139168659 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (normal vs normal)

19- 7- cgl835663

cg07494047 (cancer+normal vs (cancer+normal vs

57862713 149734481 4

cancer+normal) cancer+normal)

(normal vs normal)

19- (cancer+normal vs 7- cg2031654

cg02987482 (cancer+normal vs

6274208 cancer+normal) 156810507 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- 7- cgl010837

cg23977631 (cancer+normal vs (cancer+normal vs

100938799 156811362 2

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (normal vs normal) 7- cg0341309 (cancer+normal vs cgl 8061904

158454110 (cancer+normal vs 156811422 7 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- (cancer vs cancer) 7- cg0959520 (cancer vs cancer) cg21972382

29339076 (cancer+normal vs 156812104 2 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

2- (cancer vs cancer) 7- cg0486774

cg05038216 (cancer+normal vs

29339091 (cancer+normal vs 156812806 9

cancer+normal) cancer+normal)

(cancer vs cancer)

2- 7- cg2339324 (cancer+normal vs cg02764245 (cancer+normal vs

66803033 156813480 2 cancer+normal) cancer+normal)

2- (cancer+normal vs 7- cg0985818 (cancer+normal vs cgl3895765

66803345 cancer+normal) 156814480 8 cancer+normal) (cancer vs cancer)

20- 7- cg0002408 (cancer+normal vs cg22152407 (cancer+normal vs

23030446 156814491 6 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

20- 7- cg0257007

cgl3516746 (cancer+normal vs (normal vs normal)

3389408 156814845 9

cancer+normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- 7- cg2023565

cg20681068 (cancer+normal vs (cancer+normal vs

3389535 156815030 8

cancer+normal) cancer+normal)

(normal vs normal)

20- 7- cgl656105 (cancer+normal vs cg07003360 (cancer+normal vs

42875708 157644555 7 cancer+normal) cancer+normal)

20- (cancer+normal vs 7- cg2128001 (cancer+normal vs cg25799864

42875721 cancer+normal) 157644665 4 cancer+normal)

20- (cancer+normal vs 7- cg0132957 (cancer+normal vs cgl7810944

42876091 cancer+normal) 157698543 7 cancer+normal)

(normal vs normal)

21- 7- cg2070589 (cancer+normal vs cg04893913 (cancer+normal vs

43182367 157869970 3 cancer+normal) cancer+normal)

22- (cancer+normal vs 7- cg0906688 (cancer+normal vs cg02527346

20849196 cancer+normal) 157932951 3 cancer+normal)

(cancer vs cancer)

3- cgl593480 (cancer+normal vs cgl5511738 (cancer+normal vs 7-2672400

48700027 4 cancer+normal) cancer+normal)

(cancer vs cancer)

4- cg2671133 (cancer+normal vs cgl9602081 (cancer+normal vs 8-8821019

111553161 3 cancer+normal) cancer+normal)

(cancer vs cancer)

5- cg09528265 (cancer+normal vs Status - Hypo

146258195

cancer+normal)

(cancer vs cancer) (normal vs normal)

5- 1- cgl718159

cg26880493 (cancer+normal vs (cancer+normal vs

31855185 118165662 8

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

5- 1- cg0177834

cg08392199 (cancer+normal vs (cancer+normal vs

38556223 118427435 5

cancer+normal) cancer+normal)

(cancer vs cancer)

5- 1- cg2445711 (cancer+normal vs cgl2587766 (cancer+normal vs

38556435 155167337 8 cancer+normal) cancer+normal)

(cancer vs cancer)

5- cg0309678 (cancer+normal vs cgl8174928 (cancer+normal vs 1-15764869

38557085 5 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

5- cg0731925

cg03723506 (cancer+normal vs 1-17249877 (cancer+normal vs

38557143 3

cancer+normal) cancer+normal)

(normal vs normal)

5- (cancer+normal vs cgl552716

cg02390103 1-1847864 (cancer+normal vs

38846034 cancer+normal) 8

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- 1- cg2440877 (cancer vs cancer) cgl7528648 (cancer+normal vs

38846100 203098067 6 (cancer+normal vs

cancer+normal)

cancer+normal)

5- (cancer+normal vs cgl751748 (cancer+normal vs cg05485663 1-22303542

38846475 cancer+normal) 0 cancer+normal)

6- (cancer+normal vs cg0173097 (cancer+normal vs cg24970181 1-27687074

56716884 cancer+normal) 0 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- cg0071799

cgl0039188 (cancer+normal vs 1-44819838 (cancer+normal vs

72130209 5

cancer+normal) cancer+normal) (cancer vs cancer) (normal vs normal)

6- cg0141769

cg25210451 (cancer+normal vs 1-47078581 (cancer+normal vs

72130407 2

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

6- cgl986632

cgl5045441 (cancer+normal vs 1-47078752 (cancer+normal vs

72130432 5

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

6- 10- cg0658443

cg26162616 (cancer+normal vs (cancer+normal vs

72130539 124605905 3

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 10- cg0045845 (cancer vs cancer) cg23281154

72130547 cancer+normal) 134499528 4 (cancer+normal vs cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl344114

cg22300282 (cancer+normal vs (cancer vs cancer)

72130553 134499734 2

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 10- cg0254112 (cancer vs cancer) cg25141674 (cancer+normal vs

72130689 134499752 5 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl521607

cg00920327 (cancer+normal vs (cancer+normal vs

72130755 134567188 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 10- cg0063265

cg23778596 (cancer+normal vs (cancer+normal vs

149411498 27703336 7

cancer+normal) cancer+normal)

(cancer vs cancer)

7- cg0126120 (cancer+normal vs cg08131100 (cancer+normal vs 11-1011281

149411652 6 cancer+normal) cancer+normal)

(cancer vs cancer)

7- cgl831953 (cancer+normal vs cg03788131 (cancer+normal vs 11-1011315

149412290 3 cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

7- 11- cgl208747

cgl6735682 (cancer+normal vs (cancer+normal vs

73442353 46374124 1

cancer+normal) cancer+normal)

8- (cancer+normal vs 11- cgl924438 (cancer+normal vs cg24592790

27450047 cancer+normal) 46612744 0 cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

9- 11- cg0616816 (cancer vs cancer) cgl4632002 (cancer+normal vs

124132393 47372949 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

9- (cancer+normal vs 11- cgl035413 (cancer vs cancer) cg05939335

124132520 cancer+normal) 47372960 4 (cancer+normal vs cancer+normal)

(normal vs normal)

9- (cancer+normal vs 11- cg2549236

cgl4599233 (cancer+normal vs

131842938 cancer+normal) 57319872 3

cancer+normal)

(normal vs normal)

9- (cancer+normal vs 11- cg0047362

cgl3865488 (cancer+normal vs

137299285 cancer+normal) 62139710 4

cancer+normal)

(cancer vs cancer)

9- 11- cgl845614 (cancer+normal vs cgl4654324 (cancer+normal vs

137299436 67810268 0 cancer+normal) cancer+normal)

(normal vs normal)

9- (cancer+normal vs cg0709134

cg06657096 11-888685 (cancer+normal vs

140024858 cancer+normal) 6

cancer+normal)

(cancer vs cancer) 12- cgl952879 (normal vs normal)

9-707166 cgl4399863

(normal vs normal) 117468110 7 (cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- cg2354244 (cancer+normal vs

9-707387 cgl3877502 (normal vs normal)

22602447 9 cancer+normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(normal vs normal) 12- cg0376276 (cancer+normal vs

9-707410 cg03358592

(cancer+normal vs 33031216 0 cancer+normal) cancer+normal)

13- cgl712114 (cancer+normal vs

Status - Hypo

111719003 0 cancer+normal)

(normal vs normal)

(cancer vs cancer)

13- cgl235176 (cancer+normal vs

1-1095607 cg02971920 (cancer vs cancer)

113296192 8 cancer+normal) (cancer+normal vs

cancer+normal)

(normal vs normal)

1- (cancer vs cancer) 14- cg0069055 (cancer+normal vs cg06665322

167059365 (cancer+normal vs 104184575 4 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

1- 14- cgl497793

cg24600987 (cancer vs cancer) (cancer+normal vs

17898874 104190829 8

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

1- 14- cgl837439 (cancer+normal vs cgl3487476 (cancer+normal vs

206593025 105737848 3 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

1- 14- cgl979730

cg05230389 (cancer+normal vs (cancer+normal vs

220132091 24732234 4

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

1- 14- cg0152347

cgl0576232 (cancer+normal vs (cancer vs cancer)

220132097 45365651 4

cancer+normal) (cancer+normal vs

cancer+normal)

1- (cancer+normal vs 14- cg0303249 (cancer+normal vs cg25552768

226077287 cancer+normal) 61108227 7 cancer+normal)

1- (cancer+normal vs 14- cgl049870 (cancer+normal vs cgl4264773

226077303 cancer+normal) 64680996 3 cancer+normal)

(cancer vs cancer)

1- 14- cg2117437 (cancer+normal vs cg01554316 (cancer+normal vs

230257067 64681225 5 cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 15- cgl 148472

cg07952381 (cancer+normal vs

23040723 cancer+normal) 102157726 1

cancer+normal)

(cancer vs cancer)

(normal vs normal)

1- (cancer vs cancer) 15- cg2634451

cg22537280 (cancer+normal vs

54723213 (cancer+normal vs 22930613 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 15- cg0920410 (cancer+normal vs

10-518370 cg26718707

(cancer+normal vs 42211679 8 cancer+normal) cancer+normal)

10- (cancer+normal vs 15- cg0465617 (cancer+normal vs cg25800753

94891725 cancer+normal) 42211689 1 cancer+normal)

(normal vs normal) (normal vs normal)

11- 16- cg0931979

cgl 1069338 (cancer vs cancer) (cancer vs cancer)

130060459 12061715 7

(cancer vs cancer) (cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

11- cg0855586

cg03529598 (cancer+normal vs 16-3345604 (cancer+normal vs

1847357 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) 16- cg0374367

cgl4907310 (cancer+normal vs

2287734 (cancer+normal vs 47048004 8

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 16- cg0420565 (cancer+normal vs cgl7373759 (cancer+normal vs

76265321 67965756 5 cancer+normal) cancer+normal)

12- (cancer+normal vs 16- cg0441314 (cancer+normal vs cg04909529

104218302 cancer+normal) 67965867 8 cancer+normal)

(cancer vs cancer)

12- 16- cg2763547 (cancer+normal vs cg24961970 (cancer+normal vs

109885015 75241125 0 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 16- cgl662735

cg02419362 (cancer+normal vs (cancer+normal vs

121203948 88540175 8

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

13- 16- cg0574985

cgl9524009 (cancer+normal vs (cancer+normal vs

52735075 89472771 5

cancer+normal) cancer+normal)

14- (cancer+normal vs 17- cg0733048 (cancer+normal vs cg04384914

68759670 cancer+normal) 37322330 1 cancer+normal)

(cancer vs cancer)

15- (cancer+normal vs 17- cg0878325

cg27665327 (cancer+normal vs

80866134 cancer+normal) 40996565 3

cancer+normal)

(cancer vs cancer)

16- 17- cg0262264 (cancer+normal vs cg05028274 (cancer+normal vs

71755733 43578911 7 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16- 17- cgl717276

cg07747924 (cancer+normal vs (cancer+normal vs

78233495 62120439 1

cancer+normal) cancer+normal)

(normal vs normal)

16- cg2573296 (cancer+normal vs cg08316009 (cancer+normal vs 17-7755877

89165765 1 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

16- 17- cg2216178

cgl0398761 (cancer vs cancer) (cancer+normal vs

89169289 78337534 4

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

17- cg0401149 (cancer+normal vs

16-968682 _C g04454872 (cancer+normal vs

78338052 7 cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

17- (cancer vs cancer) 17- cgl653578

cg23346781 (cancer+normal vs 1412449 (cancer+normal vs 80395405 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) 18- cg0368211

cgl 1542336 (cancer+normal vs

4042717 (cancer+normal vs 77623598 2

cancer+normal) cancer+normal)

(normal vs normal)

17- cg0856951 (cancer+normal vs cg06421238 (cancer+normal vs 19-2424793

5993785 7 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- 19- cgl214998 (cancer+normal vs cg06909248 (cancer vs cancer)

70256462 50059027 6 cancer+normal)

(cancer+normal vs

cancer+normal) (cancer vs cancer)

17- (normal vs normal)

19- cg2129290

cg21088108 (cancer+normal vs

77075025 (cancer+normal vs

50059937 9

cancer+normal) cancer+normal)

17- (normal vs normal) cg03971338 (cancer+normal vs 19- cg0435507

79224178 (cancer+normal vs cancer+normal) 50059946 7

cancer+normal)

(normal vs normal)

17- (normal vs normal)

(cancer vs cancer) 19- cg2627416

cg22462714

79224306 (cancer+normal vs

(cancer+normal vs 50060174 6

cancer+normal) cancer+normal)

(normal vs normal)

17- (cancer vs cancer)

(cancer+normal vs cg0818297

cg27529668 2-7164527

79224770 (cancer vs cancer) cancer+normal) 5

(cancer+normal vs cancer+normal)

(normal vs normal) (normal vs normal) (cancer vs cancer) (cancer vs cancer)

17- cg2099575

cgl6366685 (cancer vs cancer) 2-7164586

80535398 (cancer vs cancer)

3

(cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

17- cg0023076

cg03454705 (cancer vs cancer)

(cancer vs cancer) 2-9388337

80535428 6 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer+normal vs cg0664528

17-96503 cg09580249 (cancer+normal vs

20-1165206

cancer+normal) 6 cancer+normal)

(normal vs normal)

18- (cancer vs cancer) (normal vs normal)

21- cgl846617

cg00137385

46288005 (cancer+normal vs

(cancer+normal vs 46726267 3

cancer+normal) cancer+normal)

(cancer vs cancer)

19- 22- cg0533314

cgl7741192 (cancer+normal vs

(cancer+normal vs

2811654 29660173 9 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

19- 3- cg0128976

cgl2028674 (cancer+normal vs

(cancer vs cancer)

39306244 125077434 9 cancer+normal)

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

2- 4- cg0875888

cg24419520 (cancer+normal vs

(cancer vs cancer)

106959257 154373479 7 cancer+normal)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- cg2757105

cgl3656404 (cancer vs cancer)

(cancer+normal vs 4-1646179

106959384 7 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

(cancer vs cancer)

2- cg2535461

cgl2793924 (cancer+normal vs

(cancer vs cancer) 4-3241813

17830624 7 cancer+normal)

(cancer+normal vs

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- (cancer vs cancer) cg2368847

cg03426602 (cancer vs cancer)

5-42756851

227312417 (cancer+normal vs 9 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl258592

cgl8313132 (cancer+normal vs 5-42756876

234526077 (cancer+normal vs

3

cancer+normal) cancer+normal)

2- cg00529371 (normal vs normal) 5-42757171 cg2192956 (cancer vs cancer) 242735324 (cancer vs cancer) 4 (cancer+normal vs

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

2-8850020 cgl 179495

cg00240378 (cancer vs cancer) (cancer+normal vs

5-92443321

6 cancer+normal) (cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

2- cgl859668

cgl 1464842 (cancer vs cancer) (cancer+normal vs

97427975 6-35766051

9 cancer+normal) (cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

20- (normal vs normal) cgl 157474

cg25225756 (cancer vs cancer)

55959405 6-5087031 (cancer+normal vs

5

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

20- (cancer vs cancer) (normal vs normal) cg0481631

cg22618720

55959549 7-1066650

(cancer+normal vs (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

21- cg2093409

cg24168308 (cancer vs cancer)

27372387 (cancer+normal vs 7-1117418

6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

21- cg0813708

cgl l321156 (cancer vs cancer)

27372396 (cancer+normal vs 7-1117540

5 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

21- (normal vs normal)

7- cg0876519

cg23269692

27372446 (cancer+normal vs (cancer+normal vs

130021519 9

cancer+normal) cancer+normal)

(cancer vs cancer)

21- 7- cg2111534 (normal vs normal) cgl 8274664

27372461 (cancer+normal vs (cancer+normal vs

130021544 6

cancer+normal) cancer+normal)

(cancer vs cancer)

21- (normal vs normal)

7- cg0824418

cg05957544

45360804 (cancer+normal vs (cancer+normal vs

130021807 1

cancer+normal) cancer+normal)

(cancer vs cancer)

21- cgl223778

cg08823554 (cancer+normal vs

46269191 (cancer+normal vs 7-44187017

4 cancer+normal) cancer+normal)

22- (cancer+normal vs cgl698208

cg00280270 (cancer+normal vs 21320131 7-924964

cancer+normal) 7 cancer+normal)

(cancer vs cancer) (normal vs normal)

22- (cancer vs cancer) cg2288454

cg01274916 (cancer vs cancer) 31062286 7-97841864

(cancer+normal vs 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) (normal vs normal) cg2109941

cg02504622

150238257 7-97844473 (cancer+normal vs

(cancer+normal vs 9

cancer+normal) cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) (normal vs normal) cg0102380

cg09433558

171412917 7-97857492 (cancer+normal vs

(cancer+normal vs 8

cancer+normal) cancer+normal)

(cancer vs cancer)

3- cgl7304531 (cancer+normal vs cgl892981 (cancer vs cancer)

197401639 7-97875293

cancer+normal) 4 (cancer+normal vs cancer+normal)

3- cgl9463199 (cancer+normal vs 7-97875333 cgl856389 (cancer vs cancer) 197401858 cancer+normal) 9 (cancer vs cancer)

(cancer+normal vs cancer+normal)

(normal vs normal)

3- 8- cg0514133 (cancer+normal vs cgl9817118 (cancer+normal vs

31494178 145048363 3 cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

3- cg0927218

cg20927547 (cancer+normal vs 8-30334348 (cancer+normal vs

31494215 6

cancer+normal) cancer+normal)

(cancer vs cancer)

3- 9- cgl460105 (cancer+normal vs cg24158324 (cancer+normal vs

55525967 130271989 3 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

9- cg2353846

3-9820588 cgl5771477 (cancer+normal vs (cancer+normal vs

140588019 8

cancer+normal) cancer+normal)

(cancer vs cancer)

4- cgl2710519 (cancer+normal vs (normal vs normal)

144275126

cancer+normal)

(cancer vs cancer)

4- cg00268149 (cancer+normal vs Status - Hyper

184017790

cancer+normal)

(normal vs normal)

(cancer vs cancer)

4- 1- cg2366015

cg23442198 (cancer vs cancer) (normal vs normal)

187126114 110626540 4

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

4- cg0433983

cg21399040 (cancer vs cancer) 1-12656114 (cancer+normal vs

187629328 7

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

4- 1- cg0714429 (normal vs normal) cg24820270 (cancer vs cancer)

187629336 182584520 6 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

4- (cancer vs cancer) 1- cg2408589 (normal vs normal) cgO 1040779

187629339 (cancer+normal vs 182584578 5 (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

4- cgl556461

cg25352342 (cancer vs cancer) 1-2163437 (normal vs normal)

187629387 9

(cancer+normal vs

cancer+normal)

(normal vs normal)

4- (cancer vs cancer) 1- cgl471169

cg24833566 (normal vs normal)

187629400 (cancer+normal vs 226925082 0

cancer+normal)

(normal vs normal)

4- (cancer vs cancer) 1- cgl634026

cgl3454542 (normal vs normal)

187629427 (cancer+normal vs 226925172 8

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 1- cg0448279

4-6945702 cg05069807 (normal vs normal)

(cancer+normal vs 226925181 4

cancer+normal)

(normal vs normal)

(cancer vs cancer) 10- cgl373733

4-6945745 cgl6574807 (normal vs normal)

(cancer vs cancer) 100993583 2

(cancer+normal vs cancer+normal)

(normal vs normal)

(cancer vs cancer) 10- cgl682529

4-7985238 cgl7630294 (normal vs normal)

(cancer+normal vs 100993826 0

cancer+normal)

(cancer vs cancer)

-+- 10- cgl369086

cg02008770 (cancer+normal vs (normal vs normal)

99668618 100993938 4

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) 10- cg0446077

cg26531174 (normal vs normal)

149546073 (cancer+normal vs 23484556 1

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) 10- cg2542357

cg09690765 (normal vs normal)

149547566 (cancer+normal vs 81158982 3

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) 10- cg0512782

cg26722544 (normal vs normal)

179393917 (cancer+normal vs 94822908 1

cancer+normal)

6- (cancer+normal vs 11- cgl599935 (cancer vs cancer) cg21239439

170038665 cancer+normal) 101990755 6 (normal vs normal)

(cancer+normal vs 11- cgl435943

6-2682491 cg00390784 (normal vs normal) cancer+normal) 119227592 5

(normal vs normal)

(cancer vs cancer) (normal vs normal)

0- 11- cg0343227

cgO 1086672 (cancer vs cancer) (cancer+normal vs

31123044 119612342 5

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

7- 11- cg0919436

cgl7677524 (cancer vs cancer) (cancer+normal vs

150069026 119612475 4

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

7- (cancer vs cancer) 11- cgl540750

cgl2613107 (normal vs normal)

150069577 (cancer+normal vs 119613061 5

cancer+normal)

(cancer vs cancer)

7- cgl406426

cg00835828 (cancer+normal vs 11-1463554 (normal vs normal)

150069890 8

cancer+normal)

(cancer vs cancer)

7- cgl059092

cg08085853 (cancer+normal vs 11-1463620 (normal vs normal)

33793736 5

cancer+normal)

(normal vs normal)

(cancer vs cancer)

7- cgl742987

cgl6233515 (cancer vs cancer) 11-1463662 (normal vs normal)

73408058 0

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

7- 11- cg2042991

cg07243141 (cancer vs cancer) (cancer+normal vs

73408060 18416535 1

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

7- cgl813153

cgl8780627 (cancer vs cancer) 11-615732 (cancer+normal vs

73408101 7

(cancer+normal vs cancer+normal) cancer+normal)

7- (normal vs normal) cg0042034

cg27099880 11-830190 (normal vs normal)

74021938 (cancer+normal vs 8 cancer+normal)

7- (cancer+normal vs cg2080100

cgl2431188 11-830320 (normal vs normal)

74021961 cancer+normal) 7

(cancer vs cancer)

8- cg0608598

_C gl4494313 (cancer+normal vs 11-830527 (normal vs normal)

18248453 5

cancer+normal)

(normal vs normal)

9- (cancer vs cancer) 12- cg2612081

cgl 3847724 (normal vs normal)

126243651 (cancer+normal vs 133000792 3

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

9- cg0680796

cgl3601936 (cancer+normal vs 12-4274034 (normal vs normal)

140198751 6

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

9- 12- cg0303071

cgl3710613 (cancer+normal vs (normal vs normal)

140574551 65218069 7

cancer+normal)

12- cgl 183240

(normal vs normal) (normal vs normal)

65218258 4

12- cg2368487

Status - Hyper (normal vs normal)

65218260 8

1- 12- cgl401932

cg20302133 (normal vs normal) (normal vs normal)

111217194 65218413 3

1- 12- cg2301330

cg06970370 (normal vs normal) (normal vs normal)

121261077 65218841 9

1- 12- cg0623406

cg05888917 (normal vs normal) (normal vs normal)

156626749 65219392 3

13- cgl293806

1-3663339 cg01793449 (normal vs normal) (normal vs normal)

28549698 8

13- cgl542723

1-3663531 cgl5472784 (normal vs normal) (normal vs normal)

28550400 2

1- 13- cg2195015

cg00778807 (normal vs normal) (normal vs normal)

43524347 28555387 5

(cancer vs cancer)

(normal vs normal) (cancer vs cancer)

11- 13- cg2221925

cg01234063 (cancer+normal vs (normal vs normal)

126226007 32605406 4

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 13- cgl694165

cg24304093 (normal vs normal) (normal vs normal)

14926738 32605611 6

(cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 14- cg2303481

cg27466845 (normal vs normal) (normal vs normal)

64397734 105714589 8

(cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 14- cgl547436

cgl7322044 (normal vs normal) (normal vs normal) 125140105 105714833 7

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(normal vs normal) (cancer vs cancer)

12- 14- cgl656154

cg22524951 (cancer+normal vs (normal vs normal)

91775247 105714843 3

cancer+normal) (cancer+normal vs cancer+normal)

12- (normal vs normal) 14- cg0123756 (cancer vs cancer) cg24338491

91775501 (cancer+normal vs 105715025 5 (cancer vs cancer) cancer+normal) (normal vs normal)

(cancer+normal vs cancer+normal)

13- 14- cg2370876

cg00282249 (normal vs normal) (normal vs normal)

37005566 23291897 3

13- 14- cg2714368

cg02478448 (normal vs normal) (normal vs normal)

37006063 38058243 8

14- 14- cg0746538

cgl5827779 (normal vs normal) (normal vs normal)

103524899 38058263 7

14- 14- cgl221245

cg24779941 (normal vs normal) (normal vs normal)

103524901 38058639 3

(normal vs normal)

14- 14- cgl098804

cg01655898 (cancer+normal vs (normal vs normal)

21439243 38060564 1

cancer+normal)

15- 15- cgl560585

cg25499543 (normal vs normal) (normal vs normal)

39871876 29395932 8

15- 15- cg0579045

cg23849826 (normal vs normal) (normal vs normal)

39872186 29396200 1

(normal vs normal)

15- 15- cg2248874

cg25908973 (normal vs normal) (cancer+normal vs

45670865 53096763 5

cancer+normal)

15- 15- cg2450044

cgl0088041 (normal vs normal) (normal vs normal)

45670872 66274709 1

15- 15- cgl842226

cg00645339 (normal vs normal) (normal vs normal)

45670875 66274767 8

16- 15- cg2590377

cg05364038 (normal vs normal) (normal vs normal)

5500503 68128025 9

17- 15- cgl421060

cgl6755500 (normal vs normal) (normal vs normal)

27918338 68128175 7

(cancer vs cancer) (cancer vs cancer)

17- (normal vs normal) cgl642709 (normal vs normal) cgl0547969 16-1202468

35084975 (cancer+normal vs 6 (cancer+normal vs

cancer+normal) cancer+normal)

17- (cancer vs cancer) 16- cg0040217

cgl0153335 (normal vs normal)

46671293 (normal vs normal) 68118754 2

(cancer vs cancer) (cancer vs cancer)

17- (cancer vs cancer) 16- cg0798922

cg02293936 (normal vs normal)

46671298 (normal vs normal) 86231948 1

(cancer+normal vs cancer+normal)

17- cg0646845

cg00482488 (normal vs normal) 17-3591377 (normal vs normal)

70216332 4

17- 17- cg0097105

cg06931941 (normal vs normal) (normal vs normal)

7486770 40573764 0

(cancer vs cancer)

19- (normal vs normal) 17- cg0992055

cg09479389 (normal vs normal)

14016729 (cancer+normal vs 61553938 7

cancer+normal)

19- 17- cg2505490

cg25397945 (normal vs normal) (normal vs normal)

37096148 61553954 7

19- 17- cg0213196 (cancer vs cancer) cgl8630667 (normal vs normal)

37096323 61554106 7 (normal vs normal)

19- 17- cgl677983

cg05020604 (normal vs normal) (normal vs normal)

37096329 79374327 9

19- 18- cgl567795

cg05661282 (normal vs normal) (normal vs normal)

58220370 47088780 7

19- 19- cgl843771 (cancer vs cancer) cg21790626 (normal vs normal)

58220494 51522894 0 (normal vs normal)

19- cgl851726

cg27049766 (normal vs normal) 19-5827811 (normal vs normal)

58220516 6

19- cg08668790 (normal vs normal) 2- cgl507707 (normal vs normal) 58220662 102803290 0

19- 2- cg2022599

cgl2506930 (normal vs normal) (normal vs normal)

58220718 218843435 9

19- 20- cg2247446

cgO 1268824 (normal vs normal) (normal vs normal)

58220818 21492914 4

(cancer vs cancer)

19- 20- cg0992310 (normal vs normal) cg06633438 (normal vs normal)

6272158 30193892 7 (cancer+normal vs

cancer+normal)

2- 3- cg0048033

cgl8106923 (normal vs normal) (normal vs normal)

123289581 187455371 1

(normal vs normal)

2- cgl370789

cg26153054 (normal vs normal) 3-27674461 (cancer+normal vs

132152814 4

cancer+normal)

(normal vs normal)

2- cgl l28215

cgl6171838 (normal vs normal) 3-63428840 (cancer+normal vs

158454083 6

cancer+normal)

(cancer vs cancer)

2- (normal vs normal) cg0618178

cgl 8061904 3-9993934 (normal vs normal)

158454110 (cancer+normal vs 4

cancer+normal)

(cancer vs cancer)

2- cg0525729 (normal vs normal) cg21442003 (normal vs normal) 4-1161247

158454243 1 (cancer+normal vs

cancer+normal)

(normal vs normal)

2- 4- cg0108456

cgl5346191 (normal vs normal) (cancer+normal vs

242743588 175444482 6

cancer+normal)

2- cg2325439

cg23428985 (normal vs normal) 4-85423132 (normal vs normal)

29338113 3

2- cgl055530

cg23255835 (normal vs normal) 5-11385520 (normal vs normal)

29338121 7

2- cg0678203

cg03135351 (normal vs normal) 5-16179135 (normal vs normal)

29338258 5

(normal vs normal)

2- cg2408212

cg26147678 (normal vs normal) 5-672872 (cancer+normal vs

61371880 1

cancer+normal)

2- 6- cgl776040

cg01648237 (normal vs normal) (normal vs normal)

61372066 100915191 5

2- cg2720939

cg05037927 (normal vs normal) 6-26172397 (normal vs normal)

61372117 5

2- cg2325290

cgl6328106 (normal vs normal) 6-711405 (normal vs normal)

61372138 2

2- 7- cgl976756

cg24757310 (normal vs normal) (normal vs normal)

61372226 100224437 2

2- 7- cg0617366

cgl8158151 (normal vs normal) (normal vs normal)

61372256 101579929 3

2- 7- cg0647159

cg09175843 (normal vs normal) (normal vs normal)

70313417 101579936 6

(cancer vs cancer)

2- 7- cg2518150 (normal vs normal) cgl7839721 (normal vs normal)

97193174 139168659 7 (cancer+normal vs

cancer+normal)

(normal vs normal)

20- 7- cg2204903

cg07003360 (cancer+normal vs (normal vs normal)

42875708 146332766 8

cancer+normal)

20- 7- cgl544015

cg09994356 (normal vs normal) (normal vs normal)

42875779 146351256 8

(normal vs normal)

20- 7- cg2031654

cgl3868604 (normal vs normal) (cancer+normal vs

42875931 156810507 9

cancer+normal) (normal vs normal)

21- 7- cg0486774

cgl7879722 (normal vs normal) (cancer+normal vs

43181729 156812806 9

cancer+normal)

(cancer vs cancer)

(normal vs normal) (cancer vs cancer)

21- 7- cg0257007

cg04893913 (cancer+normal vs (normal vs normal)

43182367 156814845 9

cancer+normal) (cancer+normal vs

cancer+normal)

3- cgl058029

cg24396624 (normal vs normal) 7-29605897 (normal vs normal)

25469860 3

3- cgl845158

cgl l291081 (normal vs normal) 7-29606289 (normal vs normal)

37033894 8

3- cgl 120361

cg05670953 (normal vs normal) 7-47576580 (normal vs normal)

37033903 6

3- cg2288312

cg21109167 (normal vs normal) 8-11540758 (normal vs normal)

37034084 5

4- 8- cgl678828

cg03248158 (normal vs normal) (normal vs normal)

122632918 142216031 6

4- 8- cg0250888

cgl9518666 (normal vs normal) (normal vs normal)

157692845 142216119 1

5- cg21051519 (normal vs normal) Status - Hypo

137225191

5- 1- cg0181489

cgl3933262 (normal vs normal) (normal vs normal)

140797172 110530427 8

5- cgl909500

cgl8188717 (normal vs normal) 1-11711141 (normal vs normal)

154230223 0

(normal vs normal)

5- 1- cgl718159

cgl8260397 (normal vs normal) (cancer+normal vs

154230438 118165662 8

cancer+normal)

(normal vs normal)

5- 1- cg0177834

cgl8110165 (normal vs normal) (cancer+normal vs

49736988 118427435 5

cancer+normal)

5- cg0593401

cg22828110 (normal vs normal) 1-1533852 (normal vs normal)

75919242 2

(normal vs normal)

6- cg0731925

cg22723502 (normal vs normal) 1-17249877 (cancer+normal vs

26240528 3

cancer+normal)

(normal vs normal)

6- cgl552716

cg21425842 (normal vs normal) 1-1847864 (cancer+normal vs

26240939 8

cancer+normal)

6- 1- cg2449013

cg06321998 (normal vs normal) (normal vs normal)

27173991 245607970 3

(normal vs normal)

6- cg0141769

cgl8055610 (normal vs normal) 1-47078581 (cancer+normal vs

30095419 2

cancer+normal)

(normal vs normal)

6- cgl986632

cg08548396 (normal vs normal) 1-47078752 (cancer+normal vs

30095549 5

cancer+normal)

6- 10- cgl 182217

cgl2534216 (normal vs normal) (normal vs normal)

30095570 102637177 5

6- 10- cg2297345

cg01528052 (normal vs normal) (normal vs normal)

30095728 102637197 9

(normal vs normal)

6- 10- cg0658443

cg27108419 (normal vs normal) (cancer+normal vs

30095762 124605905 3

cancer+normal)

6- 10- cg0276517

cg22753340 (normal vs normal) (normal vs normal)

31831489 124605963 7

6- 10- cg0673339

cg23174932 (normal vs normal) (normal vs normal)

31831502 130546208 4

6- 10- cgl017524

cgl9738463 (normal vs normal) (normal vs normal)

31831574 130546259 9 6- 10- cgl969931

cgl5219228 (normal vs normal) (normal vs normal)

35479628 130621726 7

(normal vs normal) (cancer vs cancer)

6- 10- cgl344114

cg07633853 (normal vs normal) (cancer vs cancer)

35569471 134499734 2

(cancer+normal vs cancer+normal)

7- 10- cg2721576 (normal vs normal) cg20883831 (normal vs normal)

150652948 98425148 8 (cancer vs cancer)

7- 11- cg2763138

cgl8423852 (normal vs normal) (normal vs normal)

150653001 12263892 9

7- cg2012911

cgl9585556 (normal vs normal) 11-1430940 (normal vs normal)

18535332 3

(normal vs normal)

7- 11- cg2549236

cg07114310 (normal vs normal) (cancer+normal vs

51538921 57319872 3

cancer+normal)

(normal vs normal)

7- 11- cg0047362

cgl2210255 (normal vs normal) (cancer+normal vs

72838671 62139710 4

cancer+normal)

7- 11- cg0223694

cgl3598010 (normal vs normal) (normal vs normal)

72838776 68972906 9

(normal vs normal)

7- cg0607203

cgl6735682 (cancer+normal vs 11-822402 (normal vs normal)

73442353 6

cancer+normal)

7- cg0702656

cg05822532 (normal vs normal) 11-823839 (normal vs normal)

73442531 0

(normal vs normal)

8- cg0709134

cg06773023 (normal vs normal) 11-888685 (cancer+normal vs

132918921 6

cancer+normal)

8- 12- cg2430904

cg20211463 (normal vs normal) (normal vs normal)

70623620 111664600 0

(cancer vs cancer)

(normal vs normal) 12- cg0597943

9-707166 cgl4399863 (normal vs normal)

(cancer+normal vs 111664628 3

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (normal vs normal)

12- cgl952879

9-707387 cgl3877502 (normal vs normal) (cancer+normal vs

117468110 7

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal) 12- cgl526042

9-707410 cg03358592 (normal vs normal)

(cancer+normal vs 132381902 8

cancer+normal)

12- cg0873143

Status - Hypo (normal vs normal)

132381984 5

12- cg2411324

1-1061647 cg25973293 (normal vs normal) (normal vs normal)

132882028 3

(normal vs normal)

(cancer vs cancer)

12- cgl926663

1-1095607 cg02971920 (cancer vs cancer) (normal vs normal)

46776389 5

(cancer+normal vs

cancer+normal)

(normal vs normal)

1- (cancer vs cancer) 13- cgl991612

cg06665322 (normal vs normal)

167059365 (cancer+normal vs 113242878 9

cancer+normal)

(normal vs normal)

1- (cancer vs cancer) 13- cg0860234

cg24600987 (normal vs normal)

17898874 (cancer vs cancer) 113242997 6

(cancer+normal vs cancer+normal)

1- 13- cg0059800

cgl4285365 (normal vs normal) (normal vs normal)

36643743 113243141 9

1- 13- cgl808073

cgl 1393040 (normal vs normal) (normal vs normal)

47907054 113611873 3

10- 13- cg0242002

cg05394294 (normal vs normal) (normal vs normal)

3160926 41632640 7

10- 14- cg2295871

cg02579140 (normal vs normal) (normal vs normal)

3160982 23855309 5

(normal vs normal)

10- 14- cgl979730

cg20447730 (normal vs normal) (cancer+normal vs

45719880 24732234 4

cancer+normal)

(normal vs normal) (cancer vs cancer)

11- 14- cg0152347

cg05877661 (normal vs normal) (cancer vs cancer)

1095156 45365651 4

(cancer+normal vs cancer+normal)

11- 14- cg2091733

cgl0964472 (normal vs normal) (normal vs normal)

1241885 62440685 8

11- (normal vs normal) 14- cg0823826

cg25892168 (normal vs normal)

130059549 (cancer vs cancer) 64682912 5

(normal vs normal)

11- 15- cg2634451

cg04823219 (normal vs normal) (cancer+normal vs

130059700 22930613 3

cancer+normal)

(normal vs normal)

(normal vs normal) (cancer vs cancer)

11- 16- cg0931979 (cancer vs cancer) cgl 1069338 (cancer vs cancer)

130060459 12061715 7 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(normal vs normal)

11- 16- cgl030397

cg03529598 (cancer+normal vs (normal vs normal)

1847357 50982437 8

cancer+normal)

11- 16- cgl347620

cg22081905 (normal vs normal) (normal vs normal)

2441442 75241216 4

12- 16- cg0537704

cgl6244664 (normal vs normal) (normal vs normal)

130821530 88473713 1

(normal vs normal)

12- 16- cg0574985

cg25179780 (normal vs normal) (cancer+normal vs

132849404 89472771 5

cancer+normal)

(normal vs normal)

12- cg0322684

cgl8754342 (cancer vs cancer) 17-185102 (normal vs normal)

14849268 4

(cancer vs cancer)

15- 17- cg0004198

cg20703122 (normal vs normal) (normal vs normal)

28339563 55828038 9

15- 17- cgl850100

cgl3887966 (normal vs normal) (normal vs normal)

59568712 76497386 1

(normal vs normal)

16- (normal vs normal) 17- cg2216178

cgO 1149677 (cancer+normal vs

1808230 (cancer vs cancer) 78337534 4

cancer+normal)

(normal vs normal) (normal vs normal)

16- 17- cgl653578

cg08316009 (cancer+normal vs (cancer+normal vs

89165765 80395405 8

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

16- 19- cg2689771

cgl0398761 (cancer vs cancer) (normal vs normal)

89169289 39691363 7

(cancer+normal vs

cancer+normal)

(normal vs normal) (normal vs normal)

19- cg2129290

16-968682 _C g04454872 (cancer+normal vs (cancer+normal vs

50059937 9

cancer+normal) cancer+normal)

17- cg06421238 (normal vs normal) 19- cg0435507 (normal vs normal) 5993785 (cancer+normal vs 50059946 7 (cancer+normal vs

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

17- 19- cg2627416

cg06909248 (cancer vs cancer) (cancer+normal vs

70256462 50060174 6

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

17- (cancer vs cancer) 2- cg2305653

cg22462714 (normal vs normal)

79224306 (cancer+normal vs 242977619 9

cancer+normal)

(normal vs normal) (normal vs normal) (cancer vs cancer) (cancer vs cancer)

17- cg0818297

cgl6366685 (cancer vs cancer) 2-7164527 (cancer vs cancer)

80535398 5

(cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal) (normal vs normal) (cancer vs cancer) (cancer vs cancer)

17- cg2099575

cg03454705 (cancer vs cancer) 2-7164586 (cancer vs cancer)

80535428 3

(cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal) (normal vs normal)

18- (cancer vs cancer) cg0971780 (cancer vs cancer) cg00137385 2-74375930

46288005 (cancer+normal vs 9 (cancer+normal vs

cancer+normal) cancer+normal)

18- 20- cgl501021

cgl3287668 (normal vs normal) (normal vs normal)

8718597 61150489 3

19- 20- cg2234899

cg27594157 (normal vs normal) (normal vs normal)

1235003 61979563 2

(normal vs normal)

19- 21- cgl846617

cg03284113 (normal vs normal) (cancer+normal vs

1235093 46726267 3

cancer+normal)

19- cgl737819

cgl0810394 (normal vs normal) 3-13679574 (normal vs normal)

12886980 3

19- cg2318284

cg27341866 (normal vs normal) 3-4344661 (normal vs normal)

2278618 0

19- cgl488829

cg07595134 (normal vs normal) 3-48413707 (normal vs normal)

2278708 6

19- cg0661601

cg08399733 (normal vs normal) 3-48413738 (normal vs normal)

2278773 4

(normal vs normal)

(cancer vs cancer)

19- cg0766277

cgl2028674 (cancer vs cancer) 3-64008007 (normal vs normal)

39306244 1

(cancer+normal vs

cancer+normal)

19- cg0628679

cg27196194 (normal vs normal) 3-64008041 (normal vs normal)

4054253 6

19- 4- cgl231183

cg24478966 (normal vs normal) (normal vs normal)

42460930 164391778 7

19- 4- cg2211589

cg02330271 (normal vs normal) (normal vs normal)

4835716 177198411 2

(normal vs normal)

(cancer vs cancer)

2- cg0107585

cg24419520 (cancer vs cancer) 5-1702381 (normal vs normal)

106959257 2

(cancer+normal vs

cancer+normal)

2- cgl747067

cg08093959 (normal vs normal) 5-1702470 (normal vs normal)

106959853 4

2- 5- cgl096293

cgl5139063 (normal vs normal) (normal vs normal)

106959868 179763857 0

2- cgl2606455 (normal vs normal) 6- cg0460079 (normal vs normal) 106959878 130774523 5

2- 6- cgl351786 (normal vs normal) cgl2815916 (normal vs normal)

131114432 168970787 6 (cancer vs cancer)

(normal vs normal)

(cancer vs cancer)

2- 6- cg0176939

cgl2793924 (cancer vs cancer) (normal vs normal)

17830624 169286420 2

(cancer+normal vs

cancer+normal)

(normal vs normal)

2- (cancer vs cancer) 6- cgl012210

cg00529371 (normal vs normal)

242735324 (cancer+normal vs 169286588 3

cancer+normal)

cg2752934

2-8849962 cgl0900049 (normal vs normal) 6-31322926 (normal vs normal)

6

(normal vs normal)

(cancer vs cancer) (normal vs normal) cgl 157474

2-8850020 cg00240378 (cancer vs cancer) 6-5087031 (cancer+normal vs

5

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

2- cg0481631

cgl9953799 (normal vs normal) 7-1066650 (cancer+normal vs

97427733 1

cancer+normal)

(normal vs normal)

2- (normal vs normal) 7- cg0876519

cgl2942038 (cancer+normal vs

97427895 (cancer vs cancer) 130021519 9

cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

2- 7- cg2111534

cgl 1464842 (cancer vs cancer) (cancer+normal vs

97427975 130021544 6

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

20- 7- cg0824418

cg25225756 (cancer vs cancer) (cancer+normal vs

55959405 130021807 1

(cancer+normal vs cancer+normal) cancer+normal)

20- (normal vs normal) 7- cgl743399

cg20726575 (normal vs normal) 57616191 (cancer vs cancer) 130025478 8

20- 7- cg0709688

cgl l523191 (normal vs normal) (normal vs normal) 62187126 149979234 3

22- 7- cg0422088

cgl3814677 (normal vs normal) (normal vs normal)

46809688 152524814 1

(normal vs normal)

3- cgl863263

cgl9817118 (cancer+normal vs 7-72738961 (normal vs normal)

31494178 4

cancer+normal)

(normal vs normal)

(normal vs normal)

3- cg2288454 (cancer vs cancer) cg20927547 (cancer+normal vs 7-97841864

31494215 1 (cancer+normal vs

cancer+normal)

cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

4- cg2109941

cg23442198 (cancer vs cancer) 7-97844473 (cancer+normal vs

187126114 9

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

4- cg0102380

cg21399040 (cancer vs cancer) 7-97857492 (cancer+normal vs

187629328 8

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

4- cg0498918

cg24820270 (cancer vs cancer) 8-9790928 (normal vs normal)

187629336 5

(cancer vs cancer) (cancer+normal vs

cancer+normal)

(normal vs normal)

4- (cancer vs cancer) 9- cg2122235

cgO 1040779 (normal vs normal)

187629339 (cancer+normal vs 127602615 0

cancer+normal)

(normal vs normal)

(cancer vs cancer)

4- 9- cgl364933

cg25352342 (cancer vs cancer) (normal vs normal)

187629387 131857200 0

(cancer+normal vs

cancer+normal)

(normal vs normal)

4- (cancer vs cancer) 9- cgl394143

cg24833566 (normal vs normal)

187629400 (cancer+normal vs 138437177 6

cancer+normal)

(normal vs normal)

(normal vs normal)

4- (cancer vs cancer) 9- cg2353846

cgl3454542 (cancer+normal vs

187629427 (cancer+normal vs 140588019 8

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

9- cgl445229

4-6945745 cgl6574807 (cancer vs cancer) (normal vs normal)

140770915 9

(cancer+normal vs

cancer+normal)

PRAD (cancer vs

4-7736057 cg27036376 (normal vs normal)

cancer)

(normal vs normal)

(cancer vs cancer)

4-7985238 cgl7630294 Status - Hyper

(cancer+normal vs

cancer+normal)

1- cg0415106

4-8608486 cgl 1951974 (normal vs normal) (cancer vs cancer)

116710943 2

(cancer vs cancer)

1- cg2752710

5-1291888 cgl6750953 (normal vs normal) (cancer+normal vs

116711075 8

cancer+normal)

(cancer vs cancer)

1- cgl793372

5-1292339 cg07285213 (normal vs normal) (cancer+normal vs

116711077 2

cancer+normal)

(cancer vs cancer)

5- 1- cgl627712

cg25535999 (normal vs normal) (cancer+normal vs

142757312 146556479 8

cancer+normal)

5- 1- cgl044591

cgl7603288 (normal vs normal) (cancer vs cancer)

14405747 154971922 1

(cancer vs cancer)

5- cgl058264

cgl5143268 (normal vs normal) 1-19283761 (cancer+normal vs

14405920 8

cancer+normal)

(cancer vs cancer)

6- 1- cg0366928

cgO 1402746 (normal vs normal) (cancer+normal vs

30616468 228566718 2

cancer+normal)

(cancer vs cancer)

6- 1- cgl902552

cg07889936 (normal vs normal) (cancer+normal vs

30616472 228566824 5

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

6- cg2043084

cgO 1086672 (cancer vs cancer) 1-2461820 (cancer+normal vs

31123044 7

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

6- cg0982775

cgl2090052 (normal vs normal) 1-2461823 (cancer+normal vs

35109435 2

cancer+normal)

6- cgl2835524 (normal vs normal) 1-2461834 cgl775596 (cancer vs cancer) 35109485 4

(cancer vs cancer)

6- cgl461625

cgl4151158 (normal vs normal) 1-24648696 (cancer+normal vs

38141763 1

cancer+normal)

6- cg2217632

cgl8751133 (normal vs normal) 1-24648851 (cancer vs cancer)

99842351 4

(cancer vs cancer) cgl808599

7-1037343 cg20449048 (normal vs normal) 1-33938224 (cancer+normal vs

8

cancer+normal)

(normal vs normal)

(cancer vs cancer)

7- cgl330355

cgl7677524 (cancer vs cancer) 1-33938226 (cancer vs cancer)

150069026 3

(cancer+normal vs

cancer+normal)

(normal vs normal)

7- (cancer vs cancer) cg0410893

cgl2613107 1-45250181 (cancer vs cancer)

150069577 (cancer+normal vs 9

cancer+normal)

cg0171086

7-4862349 cgl7334762 (normal vs normal) 1-48937404 (cancer vs cancer)

5

(cancer vs cancer)

7- lO- cg0509859

cg23460250 (normal vs normal) (cancer+normal vs

73223852 l l 1767379 0

cancer+normal)

(normal vs normal)

(cancer vs cancer)

7- 10- cg0942524

cgl6233515 (cancer vs cancer) (cancer vs cancer)

73408058 52178225 7

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

7- 10- cgl279988

cg07243141 (cancer vs cancer) (cancer+normal vs

73408060 74020976 5

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

7- 10- cg2510412

cgl8780627 (cancer vs cancer) (cancer vs cancer)

73408101 74021022 4

(cancer+normal vs

cancer+normal)

(normal vs normal) (cancer vs cancer)

7- 11- cg2368441

cg27099880 (cancer+normal vs (cancer+normal vs

74021938 116897558 0

cancer+normal) cancer+normal)

(cancer vs cancer)

11- cgl387473

7-960115 cgl8092351 (normal vs normal) (cancer+normal vs

129244236 9

cancer+normal)

(cancer vs cancer)

11- cg2308331

7-960411 cg20928945 (normal vs normal) (cancer+normal vs

35639656 5

cancer+normal)

(cancer vs cancer)

8- 11- cg0541513

cg07466463 (normal vs normal) (cancer+normal vs

141574207 58940866 1

cancer+normal)

(cancer vs cancer)

8- 11- cg0848100

cg07295586 (normal vs normal) (cancer+normal vs

142984467 78131601 2

cancer+normal)

(cancer vs cancer)

8- 12- cg0576988

cgl 1847597 (normal vs normal) (cancer+normal vs

22673141 89744701 9

cancer+normal)

8- (normal vs normal) 13- cgl l52140

cg23625106 (cancer vs cancer)

61789727 (cancer vs cancer) 20735532 4

14- cgl217779

8-7308492 cg20324687 (normal vs normal) (cancer vs cancer)

24837892 3

9- cgl 3847724 (normal vs normal) 14- cg2192717 (cancer vs cancer) 126243651 (cancer vs cancer) 65172436 7 (cancer+normal vs

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

ESCA_HNSC (cancer vs 15- cg2492214

(cancer+normal vs cancer) 35014270 3

cancer+normal)

15- cg0885720

Status - Hyper (cancer vs cancer)

56536865 1

(cancer vs cancer) (cancer vs cancer)

1- 15- cgl418823

cgl3912858 (cancer+normal vs (cancer+normal vs

109939840 68724065 2

cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer vs cancer) cgl 142445

cg20795569 17-1131878 (cancer vs cancer)

152085136 (cancer+normal vs 6

cancer+normal)

(cancer vs cancer)

1- 17- cg0023683

cgl0993336 (cancer+normal vs (cancer vs cancer)

207627941 38465489 2

cancer+normal)

1- 17- cgl313237

cg02497700 (cancer vs cancer) (cancer vs cancer)

244213358 46830260 0

1- 17- cg0213196 (cancer vs cancer) cgl4075221 (cancer vs cancer)

244213451 61554106 7 (normal vs normal)

(cancer vs cancer)

1- (cancer vs cancer) 17- cgl 112249

cg26114324 (cancer vs cancer)

44401857 (cancer+normal vs 74706551 3

cancer+normal)

(cancer vs cancer)

1- (cancer vs cancer) 17- cg0488061

cgl8115627 (cancer vs cancer)

44401979 (cancer+normal vs 74706567 8

cancer+normal)

(cancer vs cancer)

1- (cancer vs cancer) 18- cg0103763

cg23954153 (cancer vs cancer)

44402353 (cancer+normal vs 59560289 7

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer) 19- cg2559356

1-6546574 cg24535622 (cancer+normal vs

(cancer+normal vs 16187364 0

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 19- cgl623297

cg03204322 (cancer vs cancer) (cancer+normal vs

84767878 16187631 9

cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer) 19- cg2614916

cg05291069 (cancer+normal vs

126136435 (cancer vs cancer) 16187889 7

cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer) cgl504580

cg06299833 19-1857434 (cancer+normal vs

126136709 (cancer vs cancer) 2

cancer+normal)

10- (cancer vs cancer) 19- cg0688259

cgl3262165 (cancer vs cancer)

95326801 (cancer vs cancer) 34397628 1

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) 19- cg0287966

cg01948390 (cancer+normal vs

22850866 (cancer+normal vs 46800467 2

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) 19- cgl735529

cg03988778 (cancer+normal vs

22850891 (cancer+normal vs 51416098 4

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 19- cg0995349

cgl8494399 (cancer vs cancer) (cancer+normal vs

35441558 51416202 9

cancer+normal)

11- cgl5917625 (cancer vs cancer) 19- cgl428356 (cancer vs cancer) 46299900 51416213 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- (cancer vs cancer) 19- cg2011526

cg24281668 (cancer+normal vs

113661270 (cancer+normal vs 51416517 6

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) 19- cg2451240

cgl7405840 (cancer+normal vs

24717001 (cancer vs cancer) 51522561 0

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 19- cgl591020

cgl6322262 (cancer vs cancer)

59931110 (cancer+normal vs 51522588 8

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

14- (cancer vs cancer) 19- cg0477268

cg22821834 (cancer+normal vs

59931541 (cancer+normal vs 51522641 3

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 19- cgl843771 (cancer vs cancer) cgl5436096

59931922 (cancer+normal vs 51522894 0 (normal vs normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 19- cg0330740

cg09859398 (cancer vs cancer)

59932033 (cancer+normal vs 51568260 1

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 19- cg2010445

cg04186360 (cancer vs cancer)

59932101 (cancer+normal vs 51568523 6

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 2- cgl455751

cgl4847688 (cancer vs cancer)

59932113 (cancer+normal vs 122042345 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

14- (cancer vs cancer) 2- cg0835081

cg05217962 (cancer+normal vs

59932128 (cancer+normal vs 191045309 4

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

14- (cancer vs cancer) 2- cg0653203

cg01678172 (cancer+normal vs

59932146 (cancer+normal vs 191045430 7

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

14- (cancer vs cancer) 2- cgl531322

cg21893185 (cancer+normal vs

59932153 (cancer+normal vs 191045668 6

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 2- cgl990609

cgl6411251 (cancer vs cancer)

59932250 (cancer+normal vs 191045697 3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- (cancer vs cancer) cgl687664 (normal vs normal) cgl0014563 2-43451842

59932273 (cancer+normal vs 7 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

14- 20- cg0610240

cg08229199 (cancer+normal vs (cancer vs cancer)

59932289 30458708 3

cancer+normal)

14- 21- cg0428503

cg04329105 (cancer vs cancer) (cancer vs cancer)

59932321 46143498 3

16- (cancer vs cancer) 21- cg2502045

cg09350341 (cancer vs cancer)

55514378 (cancer vs cancer) 47402144 9

16- cgl0026203 (cancer vs cancer) 3- cg2287862 (cancer vs cancer) 66878654 (cancer vs cancer) 169379010 7 (normal vs normal)

(cancer+normal vs cancer+normal)

16- (cancer vs cancer) 3- cg0709159

cg06524479 (cancer vs cancer)

66878676 (cancer vs cancer) 187455718 3

16- (cancer vs cancer) 3- cg0882592

cgl0373196 (cancer vs cancer)

66878685 (cancer vs cancer) 193776240 9

16- (cancer vs cancer) cg2089935

_C g05440435 3-25469392 (cancer vs cancer)

66878687 (cancer vs cancer) 4

(cancer vs cancer)

16- cg2612401

cgl4986962 (cancer+normal vs 3-25469402 (cancer vs cancer)

85932214 6

cancer+normal)

16- cgl247904

cg06672120 (cancer vs cancer) 3-25469573 (cancer vs cancer)

85932383 7

(cancer vs cancer)

17- cg0348127

cg20947476 (cancer+normal vs 3-25469708 (cancer vs cancer)

26554610 4

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) cg0249924

cgl6276850 3-25469720 (cancer+normal vs

38498914 (cancer+normal vs 9

cancer+normal) cancer+normal)

17- (cancer vs cancer) cgl495771

cg22298430 3-50243260 (cancer vs cancer)

5404330 (cancer vs cancer) 8

(cancer vs cancer)

17- (cancer vs cancer) 5- cgl409895

cg27230784 (cancer+normal vs

5404337 (cancer vs cancer) 176875120 1

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) 5- cgl512695

cgl8671949 (cancer+normal vs 5404581 (cancer+normal vs 179246594 7

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cgl064171

cg25306087 5-43193681 (cancer+normal vs

72920362 (cancer vs cancer) 4

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cg2623337

cg09461395 5-43603643 (cancer+normal vs

72920598 (cancer vs cancer) 4

cancer+normal)

(cancer vs cancer)

17- cg0948928

cg00036408 (cancer vs cancer) 5-43604149 (cancer+normal vs

79316841 1

cancer+normal)

18- (cancer vs cancer) cgl413502

cgl7012181 5-55776721 (cancer vs cancer)

47087419 (cancer vs cancer) 5

(cancer vs cancer)

(cancer vs cancer)

19- (cancer vs cancer) cgl675446

cgl8816098 6-10426588 (cancer+normal vs

18335182 (cancer+normal vs 7

cancer+normal) cancer+normal)

19(cancer vs cancer) 6- cgl331997

cg06528584 (cancer vs cancer) 40S 14899 (cancer vs cancer) 146136371 5

(cancer vs cancer)

19(cancer vs cancer) 6- cg2309561

cg06936564 (cancer+normal vs 40S 14927 (cancer vs cancer) 146136563 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 6- cg0909439

cgl5046935 (cancer+normal vs (cancer+normal vs

45595006 146136749 3

cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cgl729897

cgl0788735 6-2876494 (cancer+normal vs

46974886 (cancer vs cancer) 3

cancer+normal)

(cancer vs cancer)

2- cg0173865

cg06576873 (cancer+normal vs 6-32223076 (cancer vs cancer)

121499363 0

cancer+normal)

2- (cancer vs cancer) 7- cg0391392 (cancer vs cancer) cgl8006328

121499577 (cancer+normal vs 120496827 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- (cancer vs cancer) 7- cg0102963

cgl9702675

171387064 (cancer+normal vs

(cancer+normal vs 120628874 8

cancer+normal) cancer+normal)

(cancer vs cancer)

2- 7- cgl594512

cgl3193840 (cancer vs cancer)

233285289 (cancer+normal vs

120629051 9

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl333247 (normal vs normal) cg24603464 7-25935147

238395852 (cancer vs cancer) 4 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

20- cg0933946 (normal vs normal) cg03117005 (cancer+normal vs 7-25935223

60642115 2 (cancer+normal vs cancer+normal)

cancer+normal)

22- (cancer vs cancer) cg2218772

cgl9343611 7-29185965 (cancer vs cancer) 28010528 (cancer vs cancer) 2

(cancer vs cancer)

3- cg0894673

cgl6876162 (cancer vs cancer) 7-32981826

182834217 (cancer+normal vs

1

cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) cg0306920

cg09008417 7-75535491 (cancer vs cancer)

42814854 (cancer+normal vs 4

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (cancer vs cancer) cgl312396

cg27409478 8-38323238

75834335 (cancer+normal vs

(cancer+normal vs 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- cg0040022

cg02621032 (cancer+normal vs 8-38323291

75834525 (cancer+normal vs

1

cancer+normal) cancer+normal)

4- (cancer vs cancer) cgl769662

cg21943416 8-94713190 (cancer vs cancer)

143766916 (cancer vs cancer) 9

(cancer vs cancer)

4- (cancer vs cancer) cg2226216

cg00183107 9-27528999

143767118 (cancer+normal vs

(cancer vs cancer) 8

cancer+normal)

4- (cancer vs cancer)

(cancer vs cancer) cg2124484

cg06814616 9-27529339

173961344 (cancer+normal vs

(normal vs normal) 6

cancer+normal)

4- cgl772798

cgl6405637 (cancer vs cancer) 9-27529519 (cancer vs cancer)

42399703 9

(cancer vs cancer)

5- cg00426310 (cancer+normal vs

139030390 Status - Hypo

cancer+normal)

cgl908157

5-1594579 cg08778598 (cancer vs cancer) 1-1190137 (cancer vs cancer)

1

(cancer vs cancer)

(cancer vs cancer) 1- cgl452036

5-1594676 cg21167402 (cancer+normal vs

(cancer vs cancer) 151375993 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg0491870

5-1594678 cg24960960 (cancer vs cancer) (cancer+normal vs

204057900 8

(normal vs normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cgl902899

5-1594715 cg21931717 (cancer vs cancer) (cancer+normal vs

205603040 7

(normal vs normal) cancer+normal)

(cancer vs cancer) cgl967623

5-1594733 cg08422420 (cancer vs cancer) 1-2342094 (cancer+normal vs

8

cancer+normal)

(cancer vs cancer) 1- cg2464057

5-1594808 (normal vs normal) cg06721546

(cancer+normal vs 246939216 7 (cancer vs cancer) cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

1- cg0682671

5-1594863 cg27378537 (cancer+normal vs (cancer vs cancer)

246939249 0

cancer+normal)

5- (cancer vs cancer) 1- cg2325502

cg20780811 (cancer vs cancer)

170289021 (cancer vs cancer) 246939407 0

(cancer vs cancer)

5- 1- cg0679005

cg03555227 (cancer+normal vs (cancer vs cancer)

170289070 246939453 3

cancer+normal)

(cancer vs cancer)

5- 1- cg0890644

cg23873669 (cancer+normal vs (cancer vs cancer)

170289421 246939499 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- cg2016976

cg07848601 (cancer+normal vs 1-66747598 (cancer+normal vs

170289430 6

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

6- (cancer vs cancer) 10- cg0257120 (cancer vs cancer) cg27369401

166722053 (cancer+normal vs 114591733 4 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- (cancer vs cancer) 10- cg2660694

cg02151625 (cancer+normal vs

166722060 (cancer+normal vs 123781602 7

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- (cancer vs cancer) 10- cgl l35639

cgl3045351 (cancer+normal vs

28092048 (cancer+normal vs 133783182 8

cancer+normal) cancer+normal)

(cancer vs cancer)

6- 10- cgl867948

cgl7968647 (cancer vs cancer) (cancer+normal vs

28304185 133783302 7

cancer+normal)

(cancer vs cancer)

6- 10- cg2608054

cgl3997124 (cancer vs cancer) (cancer+normal vs

28304194 15174924 5

cancer+normal)

6- 10- cgl 193776

cgl9013262 (cancer vs cancer) (cancer vs cancer)

28304216 65344030 8

(normal vs normal)

6- 11- cgl855486 (cancer vs cancer) cg09996797 (cancer vs cancer)

28304249 36652206 6 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 11- cg2203196

cg26031541 (cancer+normal vs (cancer+normal vs

28304451 62677251 4

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

6- (cancer vs cancer) 11- cg0441098 (cancer vs cancer) cg23634318

46097671 (cancer+normal vs 70282745 7 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

6- (cancer vs cancer) 11- cgl449822 (cancer vs cancer) cg06768203

46097695 (cancer+normal vs 70282774 7 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

6- (cancer vs cancer) 11- cgl404170 (cancer vs cancer) cg08211306

46097784 (cancer+normal vs 70282789 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- (cancer vs cancer) 11- cgl622707

cg24507266 (cancer+normal vs

145027948 (cancer+normal vs 77320503 2

cancer+normal) cancer+normal)

8- (cancer vs cancer) 12- cg0338978 (normal vs normal) cg06452769

145028093 (cancer vs cancer) 117429362 9 (cancer vs cancer) (cancer+normal vs (cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- (cancer vs cancer) 12- cg0665756

cgl4234406 (cancer+normal vs

145028103 (cancer+normal vs 121841372 0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- (normal vs normal) 12- cg2765390

cg00329447 (cancer+normal vs

145028170 (cancer+normal vs 124832755 1

cancer+normal) cancer+normal)

8- (cancer vs cancer) 12- cgl572114

cg02110858 (cancer vs cancer)

145028222 (normal vs normal) 133354410 2

(cancer vs cancer) (normal vs normal)

9- (cancer vs cancer) cg0247492 (cancer vs cancer) cgl3439181 12-3930923

35757158 (cancer+normal vs 6 (cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

9- (cancer vs cancer) 12- cg0201950

cg20227976 (cancer+normal vs

35757314 (cancer+normal vs 53995154 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer) 13- cgl013037

9-4299830 cgl3513288 (cancer+normal vs

(cancer+normal vs 111935412 4

cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal) (cancer vs cancer)

9- 13- cgl427000 (cancer vs cancer) cg07852402 (normal vs normal)

96713643 111935521 2 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

13- cg2161354

Status - Hypo (cancer+normal vs

111936071 9

cancer+normal)

(cancer vs cancer)

1- 14- cg2697558

cg09118017 (cancer vs cancer) (cancer+normal vs

10704886 103430286 7

cancer+normal)

(normal vs normal)

1- (cancer vs cancer) 14- cg2115675 (cancer vs cancer) cgl6401490

10704953 (cancer vs cancer) 32866773 6 (cancer+normal vs

cancer+normal)

1- (cancer vs cancer) 14- cgl670929

cg07790752 (cancer vs cancer)

147101904 (cancer vs cancer) 70235567 4

(normal vs normal)

1- 15- cg0030685 (cancer vs cancer) cgl0199857 (cancer vs cancer)

156232301 39742079 1 (cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer) 15- cg0805747 (cancer vs cancer)

1-1564422 cg00078456

(cancer vs cancer) 45803341 5 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 16- cg0654720

cgl0230257 (cancer+normal vs

161928549 (cancer+normal vs 15154082 3

cancer+normal) cancer+normal)

(normal vs normal)

1- 16- cg0053578 (cancer vs cancer) cg26663636 (cancer vs cancer)

162337134 49766785 5 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) cg2659106

cgl2486795 17-3922863 (cancer+normal vs

162337320 (cancer+normal vs 6

cancer+normal) cancer+normal) 1- 17- cg0716463

cg26813162 (cancer vs cancer) (cancer vs cancer)

162337375 47436584 1

(cancer vs cancer)

1- cg0322840

cg01833122 (cancer vs cancer) 17-5392363 (cancer+normal vs

167436541 7

cancer+normal)

1- 17- cg2322563

cgl2073436 (cancer vs cancer) (cancer vs cancer)

206958014 76989965 7

1- (cancer vs cancer) 17- cg0090214

cgl8277682 (cancer vs cancer)

228362509 (cancer vs cancer) 76993394 7

(cancer vs cancer)

(cancer vs cancer) 17- cgl419300

1-2303963 cgl8106803 (cancer+normal vs

(cancer vs cancer) 77953016 7

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 17- cg0419405

cg25211006 (cancer+normal vs

43971496 (cancer+normal vs 77953088 5

cancer+normal) cancer+normal)

(normal vs normal)

17- cgl 183087 (cancer vs cancer)

1-6355008 cg25029657 (cancer vs cancer)

78006238 6 (cancer+normal vs cancer+normal)

10- 17- cg0208090

cgl3448625 (cancer vs cancer) (cancer vs cancer)

105845238 79058333 9

(cancer vs cancer)

10- (cancer vs cancer) 17- cg2065108

_C g03444838 (cancer+normal vs

1156482 (cancer vs cancer) 80019526 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- (cancer vs cancer) 17- cgl927718

cg04784635 (cancer+normal vs

116097581 (cancer+normal vs 80560098 2

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- (cancer vs cancer) 19- cg2282463

cg24075136 (cancer+normal vs

29578013 (cancer+normal vs 13112283 5

cancer+normal) cancer+normal)

10- cgl852859

cgl 1103296 (cancer vs cancer) 19-3381526 (cancer vs cancer)

34399605 3

(cancer vs cancer)

10- (cancer vs cancer) 19- cgl674036

cgl 1322432 (cancer+normal vs

95847671 (cancer vs cancer) 34718795 4

cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) 19- cg2652236

cg02376282 (cancer vs cancer)

1543206 (cancer+normal vs 49703932 8

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) 19- cg0764282

cg08373904 (cancer+normal vs

1543275 (cancer+normal vs 56608958 2

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

11- (cancer vs cancer) 2- cg2630333

cgl5718663 (cancer+normal vs

3187784 (cancer+normal vs 206773293 9

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) 2- cg0195145

cg05584439 (cancer+normal vs

47213196 (cancer+normal vs 236964187 9

cancer+normal) cancer+normal)

(normal vs normal)

11- (cancer vs cancer) 2- cg2752900 (cancer vs cancer) cg24121967

69089119 (cancer vs cancer) 237490808 4 (cancer+normal vs cancer+normal)

11- 2- cgl620538

cg01397507 (cancer vs cancer) (cancer vs cancer)

70440395 239079215 9

11- cg08849509 (cancer vs cancer) 2- cgl339380 (cancer vs cancer) 9837208 (cancer+normal vs 239974467 9

cancer+normal)

(cancer vs cancer)

12- 2- cgl006718

cg05652090 (cancer vs cancer) (cancer+normal vs

118293169 239974554 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- (cancer vs cancer) 2- cg2147892

cg07896667 (cancer+normal vs

1726076 (cancer+normal vs 242617935 1

cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) 2- cg0330143

cgl3370010 (cancer+normal vs

33743647 (cancer vs cancer) 242617946 3

cancer+normal)

(normal vs normal)

14- cg0509789 (cancer vs cancer) cgl6051352 (cancer vs cancer) 20-5080743

103574566 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

15- 20- cgl558030

cgl3570892 (cancer+normal vs (cancer vs cancer)

45449437 62550734 4

cancer+normal)

15- (cancer vs cancer) 20- cgl452347 (normal vs normal) cgl4101284

63062631 (cancer vs cancer) 62550740 5 (cancer vs cancer)

15- 20- cgl545703 (normal vs normal) cgl6040341 (cancer vs cancer)

83544284 62562848 7 (cancer vs cancer)

(cancer vs cancer)

16- 22- cg2204113

cg03998655 (cancer vs cancer) (cancer+normal vs

1424607 39709853 7

cancer+normal)

16- 3- cgl819241

cg09556148 (cancer vs cancer) (cancer vs cancer)

18482212 128005180 9

(cancer vs cancer) (normal vs normal)

16- (cancer vs cancer) cgl871223 (cancer vs cancer) cg00838040 3-57903821

84446919 (cancer+normal vs 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) cgl415544

cg00308659 3-69220980 (cancer+normal vs

84871952 (cancer vs cancer) 6

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) cg0239543

16-928338 cg09080920 3-81604026 (cancer+normal vs

(cancer vs cancer) 4

cancer+normal)

(cancer vs cancer)

17- cg0792819

cg23715732 (cancer vs cancer) 4-1205359 (cancer+normal vs 78801851 1

cancer+normal)

(cancer vs cancer)

17- cg0629523

cg08219486 (cancer vs cancer) 4-1205447 (cancer+normal vs

78802104 8

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cg0395556

cg23019125 4-1206150 (cancer+normal vs

78820391 (cancer vs cancer) 8

cancer+normal)

(cancer vs cancer)

19- cgl036687

cg06564132 (cancer vs cancer) 4-79531297 (cancer+normal vs

14552177 8

cancer+normal)

(normal vs normal)

19- (cancer vs cancer) cg0732411 (cancer vs cancer) cgl3964781 5-80060102

14552350 (cancer vs cancer) 6 (cancer+normal vs cancer+normal)

(normal vs normal)

19- 6- cg0579814 (cancer vs cancer) cg01120132 (cancer vs cancer)

31640711 127781063 7 (cancer+normal vs cancer+normal)

(normal vs normal)

2- 6- cg2200477

cg05963605 (cancer vs cancer) (cancer vs cancer)

10395189 137495354 4

(cancer+normal vs cancer+normal)

2- (cancer vs cancer)

6- cg2056435

cgl8011760 (cancer vs cancer)

19320928 (cancer+normal vs

157910065 1

cancer+normal)

2- (cancer vs cancer) cgl2973017 cg2310481

(cancer vs cancer)

240008082 6-30552010 (cancer+normal vs

6

cancer+normal)

(cancer vs cancer) (normal vs normal)

2- (cancer vs cancer) cgl992766

cg09468399 (cancer vs cancer)

240008233 6-3150267

(cancer+normal vs 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl652675

cgl 7774001

25600752 6-34569886 (cancer vs cancer)

(cancer+normal vs 5

cancer+normal)

2- (cancer vs cancer)

7- cg2587189

cgl0155101 (cancer vs cancer)

97423319 (cancer+normal vs

135183939 0

cancer+normal)

2- (cancer vs cancer) 7- cgl760988

cgl2055459

97652489 (cancer vs cancer)

(cancer vs cancer) 157053014 7

2- (cancer vs cancer)

(cancer vs cancer)

cgl3571852 _C gl784444

97652491 7-27782764

(cancer vs cancer) (cancer+normal vs

8

cancer+normal)

(normal vs normal)

20- (cancer vs cancer) cgl542309

cgl 5032960 (cancer vs cancer)

56888536 7-39747662

(cancer vs cancer) 2 (cancer+normal vs cancer+normal)

22- (cancer vs cancer)

(cancer vs cancer) cg2652140

cg08425796

50981121 7-89842741

(cancer vs cancer) (cancer+normal vs

2

cancer+normal)

3- (cancer vs cancer)

8- cgl936515

cgl7787502 (cancer vs cancer)

123452994 (cancer+normal vs

103254722 1

cancer+normal)

3- (cancer vs cancer) 8- cgl473386

cgl7572056

195947062 (cancer vs cancer)

(cancer vs cancer) 144884056 7

(cancer vs cancer)

8-

4-1212539 cg0563726

cgl7158584 (cancer vs cancer) (cancer+normal vs

144884124 5

cancer+normal)

4- (cancer vs cancer) (cancer vs cancer) cgl252943

cg01266375

129643491 8-23538610

(cancer vs cancer) (cancer+normal vs

2

cancer+normal)

4- (cancer vs cancer)

(cancer vs cancer) cg0895145

cg06676006

151179898 8-49561756

(cancer vs cancer) (cancer+normal vs

2

cancer+normal)

5- (cancer vs cancer)

(cancer vs cancer) cg2020276

cg03898832

140868130 8-53499558

(cancer vs cancer) (cancer+normal vs

0

cancer+normal)

5- (cancer vs cancer)

(cancer vs cancer) cgl 193680

cgl4105467

149675916 8-53499582

(cancer vs cancer) (cancer+normal vs

9

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 9-

5-465330 cgl445177

cgl5026243 (cancer vs cancer)

(cancer+normal vs 100822040 1

cancer+normal)

6- (cancer vs cancer)

cg05368910 9- cgl428418

134911061 (cancer vs cancer)

(cancer vs cancer) 116355097 7

6- (cancer vs cancer)

(cancer vs cancer) 9- cgl393401

cg00273754

14305310 (cancer vs cancer) (cancer+normal vs

116812263 5

cancer+normal)

6- (cancer vs cancer) 9- cg2612716

cg09484852

157939700 (cancer vs cancer)

(cancer vs cancer) 116812388 6 (normal vs normal)

6- cgl442752 (cancer vs cancer) cgl2002139 (cancer vs cancer) 9-16204159

158478872 8 (cancer+normal vs cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) (cancer+normal vs

cgl0584587

163730283 (cancer+normal vs cancer+normal)

cancer+normal)

6- (cancer vs cancer)

cg00664730 Status - Hyper

168393930 (cancer vs cancer)

(cancer vs cancer)

6- 1- cg2752710

cgl4157549 (cancer vs cancer) (cancer+normal vs

168393963 116711075 8

cancer+normal)

(cancer vs cancer)

6- 1- cgl793372

cgl6301975 (cancer vs cancer) (cancer+normal vs

168394160 116711077 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- (cancer vs cancer) 1- cgl627712

cgl9527959 (cancer+normal vs

168394191 (cancer+normal vs 146556479 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- (cancer vs cancer) cgl058264

cgl4041603 1-19283761 (cancer+normal vs

168394198 (cancer+normal vs 8

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 1- cg0366928

cgl0367069 (cancer+normal vs

168394477 (cancer vs cancer) 228566718 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- (cancer vs cancer) 1- cgl902552

cg06251420 (cancer+normal vs

168684623 (cancer+normal vs 228566824 5

cancer+normal) cancer+normal)

6- (cancer vs cancer) 1- cg0488075 (cancer+normal vs cg08062387

168684757 (cancer vs cancer) 241695164 1 cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer) cg2043084

6-6971315 cgl8679635 1-2461820 (cancer+normal vs

(cancer+normal vs 7

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer) cg0982775

6-6971371 cgl9751937 (cancer vs cancer) 1-2461823 (cancer+normal vs

2

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer) cgl461625

7-1102344 cgl2692727 1-24648696 (cancer+normal vs

(cancer+normal vs 1

cancer+normal) cancer+normal)

(cancer vs cancer)

7- cgl808599

cg22092876 (cancer vs cancer) 1-33938224 (cancer+normal vs

120644149 8

cancer+normal)

(cancer vs cancer)

7- (cancer vs cancer) 10- cg2632917 (cancer+normal vs cgl8362281

157204364 (cancer+normal vs 100227782 8 cancer+normal) cancer+normal)

(cancer vs cancer)

7- (cancer vs cancer) lO- cg0509859

cg07993586 (cancer+normal vs

157204960 (cancer vs cancer) l l 1767379 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 10- cgl279988

7-1937120 cg04326741 (cancer+normal vs

(cancer vs cancer) 74020976 5

cancer+normal)

7- (cancer vs cancer) 11- cg2368441 (cancer vs cancer) cg22798737

94927713 (cancer vs cancer) 116897558 0 (cancer+normal vs cancer+normal)

(normal vs normal)

7- 11- cgl685841

cg09416203 (cancer vs cancer) (cancer+normal vs

94928249 116967348 5

cancer+normal)

8- (cancer vs cancer) 11- cg0964334 (cancer+normal vs cg06258648

100708621 (cancer vs cancer) 129244105 0 cancer+normal)

8- 11- cgl006898 (cancer+normal vs cgl 1829680 (cancer vs cancer)

118912508 129244122 9 cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cgl387473

cg22533992 (cancer+normal vs

119344904 (cancer vs cancer) 129244236 9

cancer+normal)

8- 11- cgl769212 (cancer+normal vs cg27039420 (cancer vs cancer)

121768955 129244505 5 cancer+normal)

(cancer vs cancer)

8- 11- cgl923841 (cancer+normal vs cg23287005 (cancer+normal vs

141588165 32916120 5 cancer+normal) cancer+normal)

(cancer vs cancer)

8- 11- cg2308331

cg01785719 (cancer vs cancer) (cancer+normal vs

143404187 35639656 5

cancer+normal)

(cancer vs cancer)

8- 11- cgl273876 (cancer+normal vs cg09605693 (cancer+normal vs

143463488 56345354 5 cancer+normal) cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cg0541513

cgl6530595 (cancer+normal vs

144788492 (cancer vs cancer) 58940866 1

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cg2238050 (cancer+normal vs cg24513449

145599544 (cancer+normal vs 63381144 8 cancer+normal) cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cg0848100

cgl8811093 (cancer+normal vs

145758588 (cancer vs cancer) 78131601 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

9- (cancer vs cancer) 12- cg0576988

cgl4173587 (cancer+normal vs

139907691 (cancer+normal vs 89744701 9

cancer+normal) cancer+normal)

(normal vs normal)

9- (cancer vs cancer) 14- cgl205198

cgl3858974 (cancer+normal vs

86149293 (cancer vs cancer) 37117758 0

cancer+normal)

(normal vs normal)

9- (cancer vs cancer) 14- cg2091049

cgl9989242 (cancer+normal vs

96069142 (cancer vs cancer) 37117947 0

cancer+normal)

(cancer vs cancer)

9- (cancer vs cancer) 14- cg2192717

cgl4505733 (cancer+normal vs

96069195 (cancer vs cancer) 65172436 7

cancer+normal)

(cancer+normal vs 14- cg2100734 (cancer+normal vs cancer+normal) 94917627 2 cancer+normal)

(cancer vs cancer)

15- cg2492214

Status - Hyper (cancer+normal vs

35014270 3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 15- cgl418823

cgl3912858 (cancer+normal vs (cancer+normal vs

109939840 68724065 2

cancer+normal) cancer+normal)

1- (cancer+normal vs 15- cg0601409 (cancer+normal vs cg21576728

113683521 cancer+normal) 77924281 2 cancer+normal)

(cancer vs cancer)

(normal vs normal)

1- (cancer vs cancer) 17- cg2200599

cg20795569 (cancer+normal vs

152085136 (cancer+normal vs 46659939 0

cancer+normal) cancer+normal)

1- (cancer+normal vs 17- cg2108202 (normal vs normal) cg26320663

152161521 cancer+normal) 46659993 8 (cancer+normal vs cancer+normal)

1- (cancer+normal vs 17- cgl446718 (cancer+normal vs cgl3575682

152850698 cancer+normal) 47516312 1 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 19- cg2559356

cgl0993336 (cancer+normal vs (cancer+normal vs

207627941 16187364 0

cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 19- cgl623297

cgl 1245333 (cancer+normal vs

220959931 cancer+normal) 16187631 9

cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 19- cg2614916

cgl2095594 (cancer+normal vs

223306857 cancer+normal) 16187889 7

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) cgl504580

cg26114324 19-1857434 (cancer+normal vs

44401857 (cancer+normal vs 2

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 19- cg0287966

cgl8115627 (cancer+normal vs

44401979 (cancer+normal vs 46800467 2

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 19- cgl735529

cg23954153 (cancer+normal vs

44402353 (cancer+normal vs 51416098 4

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer) 19- cg0995349

1-6546574 cg24535622 (cancer+normal vs

(cancer+normal vs 51416202 9

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer+normal vs 19- cgl428356

cg08856118 (cancer+normal vs

27389908 cancer+normal) 51416213 9

cancer+normal)

(cancer vs cancer)

10- (cancer+normal vs 19- cg2011526

cg26255807 (cancer+normal vs

43857904 cancer+normal) 51416517 6

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 19- cg2451240

cg04115659 (cancer+normal vs (cancer+normal vs

98480124 51522561 0

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer+normal vs 19- cg0477268

cgl2492653 (cancer+normal vs

11862867 cancer+normal) 51522641 3

cancer+normal)

(normal vs normal)

11- (cancer+normal vs 2- cg2518034

cg03673190 (cancer+normal vs

123985650 cancer+normal) 176937957 2

cancer+normal)

(cancer vs cancer)

(normal vs normal)

11- (cancer vs cancer) 2- cg0769439

cg01948390 (cancer+normal vs

22850866 (cancer+normal vs 176937971 0

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) 2- cg0899258 (cancer+normal vs cg03988778

22850891 (cancer+normal vs 176983949 1 cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

11- (cancer vs cancer) 2- cgl050308

cg02331303 (cancer+normal vs

67777823 (cancer+normal vs 177003280 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- (cancer vs cancer) 2- cg0835081

cg24281668 (cancer+normal vs

113661270 (cancer+normal vs 191045309 4

cancer+normal) cancer+normal)

12- (cancer+normal vs 2- cg0653203 (cancer vs cancer) cg06416491

39837660 cancer+normal) 191045430 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

14- (cancer+normal vs 2- cgl531322

cg00684283 (cancer+normal vs

105943425 cancer+normal) 191045668 6

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- (cancer vs cancer) cgl687664 (normal vs normal) cgl6322262 2-43451842

59931110 (cancer+normal vs 7 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 20- cgl200270 (cancer+normal vs cg22821834

59931541 (cancer+normal vs 32899806 8 cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 20- cg0663079 (cancer+normal vs cgl5436096

59931922 (cancer+normal vs 55203840 9 cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 20- cgl553649 (cancer+normal vs cg09859398

59932033 (cancer+normal vs 55203849 0 cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 20- cgl 180060 (cancer+normal vs cg04186360

59932101 (cancer+normal vs 56724999 8 cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 3- cgl596199 (cancer+normal vs cgl4847688

59932113 (cancer+normal vs 132930478 3 cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

14- (cancer vs cancer) 3- cg0620139

cg05217962 (cancer+normal vs

59932128 (cancer+normal vs 169378835 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- (cancer vs cancer) 3- cg2287862 (normal vs normal) cg01678172

59932146 (cancer+normal vs 169379010 7 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

14- (cancer vs cancer) 3- cg2451348

cg21893185 (cancer+normal vs

59932153 (cancer+normal vs 181428046 0

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 3- cgl925842 (cancer+normal vs cgl6411251

59932250 (cancer+normal vs 181428280 5 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

14- (cancer vs cancer) cg0249924

cgl0014563 3-25469720 (cancer+normal vs

59932273 (cancer+normal vs 9

cancer+normal) cancer+normal)

(cancer vs cancer)

14- cg0711511 (cancer+normal vs cg08229199 (cancer+normal vs 3-46250024

59932289 0 cancer+normal) cancer+normal)

14- (cancer+normal vs cg2717798 (cancer+normal vs cg02029441 4-25033126

61117067 cancer+normal) 3 cancer+normal)

(cancer vs cancer)

14- (cancer+normal vs 5- cgl409895

cgl0923313 (cancer+normal vs

99943086 cancer+normal) 176875120 1

cancer+normal)

16- (cancer+normal vs 5- cgl l91605 (cancer+normal vs cg01093138

83374884 cancer+normal) 177423311 4 cancer+normal)

(cancer vs cancer)

16- 5- cgOl 15207 (cancer+normal vs cgl4986962 (cancer+normal vs

85932214 179246575 3 cancer+normal) cancer+normal) (cancer vs cancer)

17- (cancer vs cancer) cg20947476 5- cgl512695

26554610 (cancer+normal vs

179246594 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer)

cgl6276850 _C g0444140

5-1877309 (cancer+normal vs

38498914 (cancer+normal vs 5 cancer+normal) cancer+normal)

17- (cancer vs cancer)

(cancer+normal vs

cg04219321 cgl064171

53341659 5-43193681

cancer+normal) (cancer+normal vs

4

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) (cancer vs cancer) cgl8671949 cg2623337

5404581 5-43603643

(cancer+normal vs (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cg06353318 cg0948928

72920378 (cancer+normal vs 5-43604149 (cancer+normal vs

1

cancer+normal) cancer+normal)

17- (cancer+normal vs 6- cgl3073699 cgO 124297 (cancer+normal vs

77805596 cancer+normal) 101839808 6 cancer+normal)

19- (cancer vs cancer) cg03720611 (cancer+normal vs cgl675446

10124152 6-10426588

cancer+normal) (cancer+normal vs

7

cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) 6- cgl8816098 cg2309082 (cancer+normal vs

18335182 (cancer+normal vs 136173085 4 cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer)

6- cgl5046935 cg2309561

45595006 (cancer+normal vs

146136563 (cancer+normal vs

5

cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer)

6- cg0909439

cgl9660239

53400545 (cancer+normal vs

146136749 (cancer+normal vs

3

cancer+normal) cancer+normal)

(cancer vs cancer)

2- 6- cg06576873 cg2232157

(cancer+normal vs (cancer+normal vs

121499363 168225923 2

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl8006328 cgl729897

121499577 (cancer+normal vs 6-2876494 -» (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer)

cgl9702675 cg0134031

171387064 6-30687511 (cancer+normal vs

(cancer+normal vs 2 cancer+normal) cancer+normal)

2- (cancer vs cancer)

(cancer+normal vs 7- cg01387102 cg0391392

238395125 cancer+normal) 120496827 (cancer+normal vs

1

cancer+normal)

20- (normal vs normal)

cg21278103 7- cg2162652 (cancer+normal vs

2928233 (cancer+normal vs

120628113 3

cancer+normal) cancer+normal)

20- (cancer+normal vs 7- cgl0360552 cg2212644 (cancer+normal vs 42142766 cancer+normal) 120628658 0 cancer+normal)

20- (cancer vs cancer)

(cancer+normal vs 7- cgl5330298 cg0102963

42143174 cancer+normal) 120628874 (cancer+normal vs

8

cancer+normal)

20- (cancer+normal vs 7- (cancer vs cancer) cgl5302378 cgl594512

42143399 cancer+normal) 120629051 (cancer+normal vs

9

cancer+normal)

(cancer vs cancer)

20- (cancer+normal vs

cg02472486 cgl333247

7-25935147 (normal vs normal) 42143502 cancer+normal) 4 (cancer+normal vs cancer+normal)

20- cg03117005 (cancer vs cancer) 7-25935223 cg0933946 (cancer vs cancer) 60642115 (cancer+normal vs 2 (normal vs normal) cancer+normal) (cancer+normal vs

cancer+normal)

(normal vs normal)

22- cg2030788

cgl5487105 (cancer+normal vs

(cancer+normal vs 7-27130090

19744051 5 cancer+normal) cancer+normal)

(normal vs normal)

22- (cancer vs cancer) cg0894673

cg21910543 (cancer+normal vs 7-32981826

19744062 (cancer+normal vs

1

cancer+normal) cancer+normal)

22- (cancer+normal vs cgl451935

cg23331322 (cancer+normal vs

7-83097669

31091262 cancer+normal) 6 cancer+normal)

3- (cancer+normal vs 8- cgl289716

cg08348121 (cancer+normal vs

170077111 cancer+normal) 124529273 4 cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) cgl 182349

cg09008417 (cancer+normal vs

8-23553798

42814854 (cancer+normal vs 6 cancer+normal) cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer)

(cancer vs cancer) cgl312396

cg27409478 8-38323238

75834335 (cancer+normal vs

(cancer+normal vs 4

cancer+normal) cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) cg0040022

cg02621032 (cancer+normal vs 8-38323291

75834525 (cancer+normal vs

1

cancer+normal) cancer+normal)

4- (cancer vs cancer)

(cancer+normal vs cg2226216

cgl7934894 9-27528999

27050410 (cancer+normal vs

cancer+normal) 8

cancer+normal)

5- (cancer vs cancer)

(cancer+normal vs cg2124484

cg02762363 9-27529339

126852998 (cancer+normal vs

cancer+normal) 6

cancer+normal)

5- (cancer+normal vs

cg04431054

126853024 Status - Hypo

cancer+normal)

(normal vs normal) (cancer vs cancer)

5- 1- cgl452036

cg22656956 (cancer+normal vs

137475177 (cancer+normal vs

151375993 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- 1- cg0491870

cg00426310 (cancer+normal vs

139030390 (cancer+normal vs

204057900 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cgl902899

5-1594808 cg06721546 (cancer+normal vs (cancer+normal vs

205603040 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) cgl967623

5-1594863 cg27378537 (cancer+normal vs 1-2342094 (cancer+normal vs

8

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

5- 1- cg2464057 (cancer vs cancer) cg03555227 (cancer+normal vs

170289070 246939216 7 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) cg2016976

cg23873669 (cancer+normal vs 1-66747598

170289421 (cancer+normal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer)

5- 10- cg0599932

cg07848601 (cancer+normal vs

(cancer+normal vs

170289430 112655570 4 cancer+normal) cancer+normal)

(normal vs normal)

(cancer+normal vs 10-

5-2253129 cg0257120 (cancer vs cancer) cg22626548

cancer+normal) 114591733 4 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer+normal vs 10- cg2660694

6-1311165 cgl7153122 (cancer+normal vs

cancer+normal) 123781602 7

cancer+normal) (cancer vs cancer)

(cancer vs cancer)

6- (cancer vs cancer) 10- cgl l35639

cg27369401 (cancer+normal vs

166722053 (cancer+normal vs 133783182 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- (cancer vs cancer) 10- cgl867948

cg02151625 (cancer+normal vs

166722060 (cancer+normal vs 133783302 7

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 10- cg2608054

cgl 1262757 (cancer+normal vs

27280423 cancer+normal) 15174924 5

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 11- cg0774070 (cancer+normal vs cgl3045351

28092048 (cancer+normal vs 130746300 5 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

6- 11- cgl855486 (cancer vs cancer) cg26031541 (cancer+normal vs

28304451 36652206 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 11- cg2203196

cg00567696 (cancer+normal vs (cancer+normal vs

46097521 62677251 4

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

6- (cancer vs cancer) 11- cg0441098 (cancer vs cancer) cg23634318

46097671 (cancer+normal vs 70282745 7 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

6- (cancer vs cancer) 11- cgl449822 (cancer vs cancer) cg06768203

46097695 (cancer+normal vs 70282774 7 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

6- (cancer vs cancer) 11- cgl404170 (cancer vs cancer) cg08211306

46097784 (cancer+normal vs 70282789 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

7- (cancer+normal vs 11- cgl622707

cg20706768 (cancer+normal vs

55225183 cancer+normal) 77320503 2

cancer+normal)

(normal vs normal)

8- (cancer+normal vs 12- cg0338978 (cancer vs cancer) cg23681110

140847721 cancer+normal) 117429362 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- (cancer vs cancer) 12- cg0665756

cg24507266 (cancer+normal vs

145027948 (cancer+normal vs 121841372 0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- (cancer vs cancer) 12- cg2765390

cg06452769 (cancer+normal vs

145028093 (cancer+normal vs 124832755 1

cancer+normal) cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 12- cgl879319 (cancer+normal vs cgl4234406

145028103 (cancer+normal vs 131390894 8 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

8- (normal vs normal) cg0247492 (cancer vs cancer) cg00329447 12-3930923

145028170 (cancer+normal vs 6 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

9- (cancer+normal vs 12- cg0201950

cg26805528 (cancer+normal vs

131872542 cancer+normal) 53995154 8

cancer+normal)

9- cgl3439181 (cancer vs cancer) 13- cgl013037 (cancer vs cancer) 35757158 (cancer vs cancer) 111935412 4 (cancer+normal vs

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

9- (cancer vs cancer) 13- cg2279534

cg20227976 (cancer+normal vs

35757314 (cancer+normal vs 111935508 5

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal) (cancer vs cancer) 13- cgl427000 (cancer vs cancer)

9-4299830 cgl3513288

(cancer+normal vs 111935521 2 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

9- 13- cg2161354

cg07852402 (normal vs normal) (cancer+normal vs

96713643 111936071 9

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

9- 14- cg2697558

cgl4374754 (cancer+normal vs (cancer+normal vs

96714295 103430286 7

cancer+normal) cancer+normal)

(normal vs normal)

9- 14- cg2731279 (cancer+normal vs cg22902266 (cancer+normal vs

96714313 105213100 8 cancer+normal) cancer+normal)

(normal vs normal)

14- cg2115675 (cancer vs cancer)

Status - Hypo

32866773 6 (cancer+normal vs

cancer+normal)

(normal vs normal)

1- (cancer+normal vs 15- cg0030685 (cancer vs cancer) cg20318235

10707917 cancer+normal) 39742079 1 (cancer+normal vs

cancer+normal)

(normal vs normal)

(normal vs normal)

1- 15- cg0805747 (cancer vs cancer) cg03962214 (cancer+normal vs

10707953 45803341 5 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

15- cg0239512 (cancer+normal vs

1-1564920 cgl7122213 (cancer+normal vs

75104987 7 cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

1- (cancer vs cancer) 15- cgl518971

cgl0230257 (cancer+normal vs

161928549 (cancer+normal vs 79723173 5

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 16- cg0654720

cgl2486795 (cancer+normal vs

162337320 (cancer+normal vs 15154082 3

cancer+normal) cancer+normal)

(normal vs normal)

1- (cancer+normal vs 16- cg0053578 (cancer vs cancer) cgl 1742472

18010807 cancer+normal) 49766785 5 (cancer+normal vs

cancer+normal)

(normal vs normal)

1- 17- cg0801373 (cancer+normal vs cg21101726 (cancer+normal vs

204124158 35480754 7 cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs cg2659106

cg00465927 17-3922863 (cancer+normal vs

26190114 cancer+normal) 6

cancer+normal)

(cancer vs cancer)

(cancer+normal vs cg0322840

1-3623605 cg21418707 17-5392363 (cancer+normal vs

cancer+normal) 7

cancer+normal)

(normal vs normal)

1- (cancer+normal vs cg2035388

cg06654076 17-663064 (cancer+normal vs

43202523 cancer+normal) 4

cancer+normal) (cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 17- cgl419300

cg25211006 (cancer+normal vs

43971496 (cancer+normal vs 77953016 7

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer+normal vs 17- cg0419405

cgl9853077 (cancer+normal vs

105216262 cancer+normal) 77953088 5

cancer+normal)

(cancer vs cancer) (normal vs normal)

10- (cancer vs cancer) 17- cgl 183087 (cancer vs cancer) cg04784635

116097581 (cancer+normal vs 78006238 6 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 17- cg2065108

cg25724837 (cancer+normal vs (cancer+normal vs

123493091 80019526 0

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer+normal vs 17- cgl927718

cg26472690 (cancer+normal vs

134458209 cancer+normal) 80560098 2

cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer) 17- cg0789177 (cancer+normal vs cg24075136

29578013 (cancer+normal vs 80560124 4 cancer+normal) cancer+normal)

(cancer vs cancer)

10- cg0930550 (cancer+normal vs cgl6862260 (cancer+normal vs 17-9088206

88445516 3 cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) 19- cg2298369 (cancer+normal vs cg02376282

1543206 (cancer+normal vs 13110842 4 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) 19- cg2282463

cg08373904 (cancer+normal vs

1543275 (cancer+normal vs 13112283 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 19- cgl674036

cg08129093 (cancer+normal vs (cancer+normal vs

17803389 34718795 4

cancer+normal) cancer+normal)

(normal vs normal)

11- (cancer vs cancer) cg2202279 (cancer+normal vs cgl5718663 19-5587909

3187784 (cancer+normal vs 7 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) 19- cg0764282

cg05584439 (cancer+normal vs

47213196 (cancer+normal vs 56608958 2

cancer+normal) cancer+normal)

(normal vs normal)

11- 2- cgl 103264 (cancer+normal vs cg24568082 (cancer+normal vs

69151092 151112658 0 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 2- cg2630333

cg08849509 (cancer+normal vs (cancer+normal vs

9837208 206773293 9

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer+normal vs 2- cg0195145

cg02528386 (cancer+normal vs

117190080 cancer+normal) 236964187 9

cancer+normal)

(normal vs normal)

12- (cancer+normal vs 2- cg2752900 (cancer vs cancer) cg24854010

1726033 cancer+normal) 237490808 4 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- (cancer vs cancer) 2- cgl006718

cg07896667 (cancer+normal vs

1726076 (cancer+normal vs 239974554 2

cancer+normal) cancer+normal)

13- cg04769514 (cancer+normal vs 2- cg0808148 (cancer+normal vs 30088640 cancer+normal) 242617771 5 cancer+normal)

13- (normal vs normal) (cancer vs cancer) cg02381064 2- cg2147892

30088771 (cancer+normal vs

242617935 (cancer+normal vs

1

cancer+normal) cancer+normal)

(normal vs normal)

14- (cancer vs cancer) cgl0348368 2- cg0330143

105851883 (cancer+normal vs

242617946 (cancer+normal vs

3

cancer+normal) cancer+normal)

14- (cancer+normal vs

cgl0888242 cg2347822

2-46113875 (cancer+normal vs

55138530 cancer+normal) 5 cancer+normal)

(normal vs normal)

14- (cancer+normal vs

cgl5313956 cg0509789 (cancer vs cancer)

91744445 20-5080743

cancer+normal) 9 (cancer+normal vs cancer+normal)

15- (cancer vs cancer)

(cancer+normal vs 22- cg09970590 cg2204113

37379321 cancer+normal) 39709853 (cancer+normal vs

7

cancer+normal)

(normal vs normal)

15- (cancer+normal vs

cg20935245 cgl871223 (cancer vs cancer)

42234343 3-57903821

cancer+normal) 1 (cancer+normal vs cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer) cgl3570892 cgl415544

45449437 (cancer+normal vs 3-69220980 (cancer+normal vs

6

cancer+normal) cancer+normal)

(normal vs normal)

16- (cancer vs cancer) cg05396425 Cg0239543

4587038 (cancer+normal vs 3-81604026 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) (cancer vs cancer) cg00838040 Cg0792819

84446919 4-1205359

(cancer+normal vs (cancer+normal vs

1

cancer+normal) cancer+normal)

(normal vs normal)

16- (cancer vs cancer) cgO 1779679 Cg0629523

87857222 (cancer+normal vs 4-1205447 (cancer+normal vs

8

cancer+normal) cancer+normal)

16- (cancer vs cancer)

(cancer+normal vs

cg01829163 Cg0395556

87871160 4-1206150

cancer+normal) (cancer+normal vs

8

cancer+normal)

16- (cancer+normal vs (normal vs normal) cg02614661 Cgl483362

87878292 4-54667491

cancer+normal) 6 (cancer+normal vs cancer+normal)

17- (cancer vs cancer)

(cancer+normal vs

cg24945092 Cgl036687

11872861 4-79531297

cancer+normal) (cancer+normal vs

8

cancer+normal)

(normal vs normal)

17- (cancer+normal vs

cg26026296 Cg0732411 (cancer vs cancer)

47629873 5-80060102

cancer+normal) 6 (cancer+normal vs cancer+normal)

(normal vs normal)

17- (cancer+normal vs 6- cgl7714010 Cg0579814 (cancer vs cancer)

78968450 cancer+normal) 127781063 7 (cancer+normal vs cancer+normal)

(normal vs normal)

17- (cancer+normal vs 6- cg03916756 Cg2200477 (cancer vs cancer)

79032487 cancer+normal) 137495354 4 (cancer+normal vs cancer+normal)

17- (cancer vs cancer)

(cancer+normal vs 6- cgl8173351 Cg2056435

79056117 cancer+normal) 157910065 (cancer+normal vs

1

cancer+normal)

17-927457 (cancer+normal vs 6- cg22006392 Cg2428085 (cancer+normal vs cancer+normal) 160201987 1 cancer+normal)

18- (cancer+normal vs

cg24245840 Cg2310481 (cancer vs cancer)

28572450 6-30552010

cancer+normal) 6 (cancer+normal vs cancer+normal)

18- (cancer+normal vs

cgl6536399 cg2063506

6-30552025 (cancer+normal vs

77230665 cancer+normal) 7 cancer+normal)

(normal vs normal)

19- (cancer+normal vs

cg07962882 cgl992766 (cancer vs cancer)

1117289 6-3150267

cancer+normal) 1 (cancer+normal vs cancer+normal)

19- (cancer+normal vs

cg09432775 cgl614532

6-36020012 (cancer+normal vs

1117453 cancer+normal) 4 cancer+normal)

19- (cancer vs cancer)

(cancer+normal vs

cg08006956 7- cg2587189

18418056 cancer+normal) 135183939 (cancer+normal vs

0

cancer+normal)

19- (cancer vs cancer)

(cancer+normal vs

cg00351537 _C gl784444

7580275 7-27782764

cancer+normal) (cancer+normal vs

8

cancer+normal)

(normal vs normal)

2- (normal vs normal)

cg21517506 cgl542309 (cancer vs cancer)

235242882 (cancer+normal vs 7-39747662

2

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer)

cg09468399 cgl387941

7-7474236 (cancer+normal vs

240008233 (cancer+normal vs 1 cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer)

cgl7774001 cg0020727

7-778962 (cancer+normal vs

25600752 (cancer+normal vs 9 cancer+normal) cancer+normal)

2- (cancer vs cancer)

(cancer+normal vs

cgl7091056 cg2652140

54315563 7-89842741

cancer+normal) (cancer+normal vs

2

cancer+normal)

2- (normal vs normal)

cg23574298 cg0583250

(cancer+normal vs 7-99515080 (cancer+normal vs

55382186 9

cancer+normal) cancer+normal)

20- (cancer vs cancer)

(cancer+normal vs

cgl 1252765 8- cgl 936515

36151120 cancer+normal) 103254722 (cancer+normal vs

1

cancer+normal)

20- (normal vs normal) (normal vs normal) cg01572549 cg2371936

60926800 (cancer+normal vs 8-12594834

7 (cancer+normal vs cancer+normal) cancer+normal)

22- (cancer vs cancer)

(cancer+normal vs

cg08819022 8- cg0563726

18531447 cancer+normal) 144884124 (cancer+normal vs

5

cancer+normal)

22- (cancer vs cancer)

(cancer+normal vs

cgl8253910 cgl252943

30230951 8-23538610

cancer+normal) (cancer+normal vs

2

cancer+normal)

22- (cancer vs cancer)

(cancer+normal vs

cg26241650 cg0895145

40417538 8-49561756

cancer+normal) (cancer+normal vs

2

cancer+normal)

3- (normal vs normal) (cancer vs cancer) cg22607164 cg2020276

(cancer+normal vs

184349562 8-53499558 (cancer+normal vs

0

cancer+normal) cancer+normal)

3- (cancer vs cancer)

(cancer+normal vs

cg24335984 cgl 193680

50361554 8-53499582

cancer+normal) (cancer+normal vs

9

cancer+normal)

3- (cancer+normal vs 9- (cancer vs cancer) cg22475071 cgl393401

64338594 cancer+normal) 116812263 (cancer+normal vs

5

cancer+normal)

4- (cancer+normal vs 9- cgl5403758 cgl380278 (cancer+normal vs

166428151 cancer+normal) 130027116 9 cancer+normal)

5- (cancer+normal vs

cgl9416326 cgl442752

9-16204159 (normal vs normal)

175955353 cancer+normal) 8 (cancer vs cancer) (cancer+normal vs cancer+normal)

(cancer vs cancer)

5- cg2124571 (cancer+normal vs cg20748242 (cancer+normal vs 9-93943683

175955925 8 cancer+normal) cancer+normal)

(normal vs normal)

5-393347 cgl7287155 (cancer+normal vs (normal vs normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5-465330 cgl5026243 Status - Hyper

(cancer+normal vs

cancer+normal)

(normal vs normal)

5- cg2502028

cg08853399 (cancer+normal vs 1-18956947 (normal vs normal)

65528850 6

cancer+normal)

6- (cancer+normal vs cgl l65122

cgl9147483 1-20512944 (normal vs normal)

12355642 cancer+normal) 0

6- (cancer+normal vs 1- cgl864217

cg00407393 (normal vs normal)

158464296 cancer+normal) 228195779 7

(cancer vs cancer)

6- (cancer vs cancer) cg2043119

cgl0584587 1-86043795 (normal vs normal)

163730283 (cancer+normal vs 1

cancer+normal)

6- (cancer+normal vs cgl695296

cg06389605 10-8089182 (normal vs normal)

168147420 cancer+normal) 3

(cancer vs cancer)

6- (cancer vs cancer) cg2028196

cgl9527959 10-8089733 (normal vs normal)

168394191 (cancer+normal vs 2

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cg0040754

cgl4041603 10-8094860 (normal vs normal)

168394198 (cancer+normal vs 6

cancer+normal)

(cancer vs cancer)

(normal vs normal)

6- (cancer vs cancer) 11- cgl685841

cg06251420 (cancer+normal vs

168684623 (cancer+normal vs 116967348 5

cancer+normal) cancer+normal)

6- (cancer+normal vs 11- cgl560342

cg09579704 (normal vs normal)

30166164 cancer+normal) 13300592 4

(cancer vs cancer)

(cancer vs cancer) 12- cg0323955

6-6971315 cgl8679635 (normal vs normal)

(cancer+normal vs 54339653 2

cancer+normal)

(cancer vs cancer)

13- cg2552496

6-6971335 cg09146892 (cancer+normal vs (normal vs normal)

20735819 2

cancer+normal)

(normal vs normal)

(cancer vs cancer)

14- cg2639754

6-6971371 cgl9751937 (cancer vs cancer) (normal vs normal)

37116121 9

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(normal vs normal) (cancer vs cancer) 14- cgl205198

7-1102344 cgl2692727 (cancer+normal vs

(cancer+normal vs 37117758 0

cancer+normal) cancer+normal)

(cancer+normal vs 14- cg0589780

7-1102375 cg02733842 (normal vs normal) cancer+normal) 37117862 9

(normal vs normal)

7- (cancer+normal vs 14- cg2091049

cgl6852756 (cancer+normal vs

130630462 cancer+normal) 37117947 0

cancer+normal)

7- cgl8362281 (cancer vs cancer) 14- cg0184394 (normal vs normal) 157204364 (cancer vs cancer) 37124434 6

(cancer+normal vs

cancer+normal)

(normal vs normal)

14- cg0097031

7-2094977 cg22717323 (cancer+normal vs (normal vs normal)

37125914 3

cancer+normal)

(normal vs normal)

14- cg2365597

7-4231054 cg03976326 (cancer+normal vs (normal vs normal)

37126582 0

cancer+normal)

(cancer+normal vs 14- cg0441579

7-6192053 cg22136051 (normal vs normal) cancer+normal) 37128586 8

(normal vs normal)

8- 14- cg0745925

cgl 1007190 (cancer+normal vs (normal vs normal)

141566084 37130212 2

cancer+normal)

(cancer vs cancer)

8- 14- cgl836109

cg23287005 (cancer+normal vs (normal vs normal)

141588165 37136391 8

cancer+normal)

8- (cancer+normal vs 14- cgl281144

cg05827089 (normal vs normal)

141588242 cancer+normal) 60972853 9

(cancer vs cancer)

8- 14- cgl542554

cg09605693 (cancer+normal vs (normal vs normal)

143463488 61118751 1

cancer+normal)

(normal vs normal)

8- 14- cgl300784

cgl6888603 (cancer+normal vs (normal vs normal)

144696651 61120662 3

cancer+normal)

(normal vs normal)

8- 15- cgl712422

cgl0299941 (cancer+normal vs (normal vs normal)

145009137 83953880 4

cancer+normal)

(normal vs normal)

8- 15- cg0652322

cg08159271 (cancer+normal vs (normal vs normal)

145009241 83953883 4

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 15- cg0701625

cg24513449 (normal vs normal)

145599544 (cancer+normal vs 83953929 8

cancer+normal)

8- (cancer+normal vs 17- cg0932834

cg22623649 (normal vs normal)

99179021 cancer+normal) 46620347 9

(normal vs normal)

9- (cancer+normal vs 17- cg2200599

cgl4327394 (cancer+normal vs

116337285 cancer+normal) 46659939 0

cancer+normal)

(cancer vs cancer)

(normal vs normal)

9- (cancer vs cancer) 17- cg2108202

cgl4173587 (cancer+normal vs

139907691 (cancer+normal vs 46659993 8

cancer+normal) cancer+normal)

17- cg2720467

(normal vs normal) (normal vs normal)

46831623 1

18- cg2541615

Status - Hyper (normal vs normal)

43355414 3

1- 18- cgl808844

cgl5393490 (normal vs normal) (normal vs normal)

207996459 43355547 2

1- 2- cg0067467

cgl6909962 (normal vs normal) (normal vs normal)

229406711 176931680 9

2- cg0045962

1-2391317 cg07700843 (normal vs normal) (normal vs normal)

176936581 3

(normal vs normal)

2- cg2518034

1-2391347 cg02850689 (normal vs normal) (cancer+normal vs

176937957 2

cancer+normal)

(normal vs normal)

1- 2- cg0769439

cg06520846 (normal vs normal) (cancer+normal vs

42921582 176937971 0

cancer+normal)

1- cg06346081 (normal vs normal) 2- cg0780235 (normal vs normal) 42921584 176956573 0

1- 2- cg2670810

cg02994349 (normal vs normal) (normal vs normal)

66999753 176983815 0

1- 2- cgl499148

cg25203031 (normal vs normal) (normal vs normal)

66999813 176987404 7

10- 2- cg0957802

cg06382559 (normal vs normal) (normal vs normal)

102896640 176987411 8

10- 2- cg0473964

cg20120208 (normal vs normal) (normal vs normal)

102896869 176987462 7

10- 2- cg2254173

cgl4383658 (normal vs normal) (normal vs normal)

102899262 176988203 5

10- 2- cgl423666

cg05482942 (normal vs normal) (normal vs normal)

102899285 176988284 2

10- 2- cg2582027

cg27336068 (normal vs normal) (normal vs normal)

1336103 177001909 9

(normal vs normal)

11- 2- cgl050308

cg08537660 (normal vs normal) (cancer+normal vs

12699661 177003280 3

cancer+normal)

11- 2- cg0058681

cg21163960 (normal vs normal) (normal vs normal)

35441777 200329872 7

11- 2- cg0925067

cgl0159951 (normal vs normal) (normal vs normal)

35441881 200330782 8

11- 2- cg0924076

cgl8220961 (normal vs normal) (normal vs normal)

69785905 200330851 3

11- 2- cg2710960

cgl4708990 (normal vs normal) (normal vs normal)

76839217 200332025 0

12- 2- _C g0744447

cg22431093 (normal vs normal) (normal vs normal)

32654992 200332380 3

13- 2- cg2434506

cgl6728323 (normal vs normal) (normal vs normal) 111212174 200334439 2

13- 2- cg0791319

cg06255601 (normal vs normal) (normal vs normal)

51086835 200334901 7

13- 2- cg2574056

cg20100768 (normal vs normal) (normal vs normal)

80706924 200335101 5

13- 2- cg0079393

cgl8252102 (normal vs normal) (normal vs normal)

98796790 234847769 5

14- cg0995025

cgl7923947 (normal vs normal) 2-64836449 (normal vs normal)

50584005 6

16- cg2747037

cg09451235 (normal vs normal) 2-64836764 (normal vs normal)

67433458 3

(normal vs normal)

16- 3- cg0620139

cg05390968 (normal vs normal) (cancer+normal vs

86598792 169378835 3

cancer+normal)

(cancer vs cancer)

16- 3- cg2287862 (normal vs normal) cg09814487 (normal vs normal)

86598824 169379010 7 (cancer+normal vs

cancer+normal)

17- 3- cg0412068

cgl4826891 (normal vs normal) (normal vs normal)

32404422 169384410 6

(normal vs normal)

17- 3- cg2451348

cg21342910 (normal vs normal) (cancer+normal vs

48042779 181428046 0

cancer+normal)

17- cg0968044

cg23634124 (normal vs normal) 4-1037615 (normal vs normal)

48049952 7

17- 4- cg0314956

cgl6312900 (normal vs normal) (normal vs normal)

48628397 109092769 5

17- 5- cg0422342

cgl2765405 (normal vs normal) (normal vs normal)

48628455 134363877 0

17- 5- cg0039666

cg05247809 (normal vs normal) (normal vs normal)

66194706 134364387 7

17- cgl3674575 (normal vs normal) 5- cgl267310 (normal vs normal) 66195134 134364717 3

17- 5- cg0983917

cg09396295 (normal vs normal) (normal vs normal)

66196681 134376247 0

17- 5- cgl344176

cgl4431361 (normal vs normal) (normal vs normal)

70611386 134376442 6

17- cgl607219

cg07114544 (normal vs normal) 5-2741047 (normal vs normal)

9110369 2

19- cg2463019

cg26578856 (normal vs normal) 5-2748369 (normal vs normal)

11998651 5

19- cg0250905

cg25383503 (normal vs normal) 5-2753746 (normal vs normal)

18714552 8

19- _C gl394446

cg02360514 (normal vs normal) 5-2753852 (normal vs normal)

45975990 8

19- cg2016880

cgl2542255 (normal vs normal) 6-10382828 (normal vs normal)

45976195 6

2- cgl755776

cg22572908 (normal vs normal) 6-10420696 (normal vs normal)

131722274 6

2- cg0068958

cgl0004780 (normal vs normal) 6-10420798 (normal vs normal)

131722307 0

2- cgl012940

cgl6682903 (normal vs normal) 6-10421001 (normal vs normal)

158694670 8

2- cgl499390

cgl4070755 (normal vs normal) 6-10421069 (normal vs normal)

238394933 0

2- cg0240772

cgl7187163 (normal vs normal) 6-10421372 (normal vs normal)

238395007 0

2- cg0276684

cg00470044 (normal vs normal) 6-28956577 (normal vs normal)

28456184 5

2- 7- cg2305803

cg23229261 (normal vs normal) (normal vs normal)

63284066 158824108 7

(cancer vs cancer)

2- cgl333247 (normal vs normal) cg05092308 (normal vs normal) 7-25935147

63285365 4 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

2- cg0933946 (normal vs normal) cgl9351026 (normal vs normal) 7-25935223

63285425 2 (cancer+normal vs

cancer+normal)

20- cg0893478

cg24752267 (normal vs normal) 7-27196759 (normal vs normal)

20352002 5

(normal vs normal)

20- cg2296491

cg21278103 (cancer+normal vs 7-27286075 (normal vs normal)

2928233 8

cancer+normal)

21- cg2250508

cgl4288673 (normal vs normal) 7-96639411 (normal vs normal)

19258040 6

22- cg0938814

cg06782697 (normal vs normal) 7-96641477 (normal vs normal)

19743336 0

22- cg2570767

cg26520942 (normal vs normal) 7-96643539 (normal vs normal)

19743892 6

(normal vs normal)

22- cg2326203

cgl5487105 (cancer+normal vs 7-96647021 (normal vs normal) 19744051 6

cancer+normal)

(normal vs normal)

22- cg2592898

cg21910543 (cancer+normal vs 7-96647079 (normal vs normal) 19744062 6

cancer+normal)

22- cg0168001

cgl6076038 (normal vs normal) 7-96647117 (normal vs normal) 19744078 0

22- cg0038819

cg20361154 (normal vs normal) 7-96647323 (normal vs normal) 22862884 5

22- cg0935911

cg02100011 (normal vs normal) 7-96650096 (normal vs normal)

38635773 4

3- cgl3621410 (normal vs normal) 7-96650171 cgl204138 (normal vs normal) 136537694 7

3- cg0883511

cgl 1862731 (normal vs normal) 7-96650192 (normal vs normal)

194408516 3

3- cgl488891

cg09652652 (normal vs normal) 8-99951420 (normal vs normal)

194408845 6

3- cg0302055

cg00352417 (normal vs normal) 8-99951730 (normal vs normal)

194408901 4

3- cg0699228

cgl0623840 (normal vs normal) 8-99952047 (normal vs normal)

194408965 5

3- cg2292070

cg20372886 (normal vs normal) 8-99955610 (normal vs normal)

42094749 0

3- cg0476860

cg26295272 (normal vs normal) 8-99960148 (normal vs normal)

58045340 2

4- cg0240987

cgl4376467 (normal vs normal) 8-99960498 (normal vs normal)

86851411 8

5- cgl3707560 (normal vs normal) Status - Hypo

137474700

5- cg0635670

cgl6354091 (normal vs normal) 1-17760589 (normal vs normal)

137474830 8

5- 1- cg0563816

cg09047573 (normal vs normal) (normal vs normal)

137474905 180911763 5

5- 1- cg0375090

cg04233770 (normal vs normal) (normal vs normal)

137475002 193077840 3

(normal vs normal)

(normal vs normal)

5- 1- cg2464057 (cancer vs cancer) cg22656956 (cancer+normal vs

137475177 246939216 7 (cancer+normal vs

cancer+normal)

cancer+normal)

5- cgl722604

cg20452230 (normal vs normal) 1-37973652 (normal vs normal)

137475379 2

(normal vs normal)

5- 10- cg0257120 (cancer vs cancer) cg23340350 (normal vs normal)

72529100 114591733 4 (cancer+normal vs

cancer+normal)

5- 10- cgl500357

cgl7791977 (normal vs normal) (normal vs normal)

72529127 133529939 0

5- 10- cgl572814

cg23517208 (normal vs normal) (normal vs normal)

72530472 26678169 6

5- 11- cg0884773

cgl9092317 (normal vs normal) (normal vs normal)

72739768 102206714 7

(normal vs normal)

6- 11- cgl855486 (cancer vs cancer) cg08015382 (normal vs normal)

12365899 36652206 6 (cancer+normal vs

cancer+normal)

6- 11- cgl996089

cg01555614 (normal vs normal) (normal vs normal)

50786369 63776653 1

6- 11- cg0523328

cgl7507887 (normal vs normal) (normal vs normal)

50786511 64120728 9

6- 11- cg0309422

cgl8886245 (normal vs normal) (normal vs normal)

50792868 66556756 6

7- 11- cg0471704

cgl4525310 (normal vs normal) (normal vs normal)

29186889 69468789 5

7- 11- cg0272353

cg04636841 (normal vs normal) (normal vs normal)

63768139 69468991 3

7- 11- cg0034793

cgl8676790 (normal vs normal) (normal vs normal)

97680731 69469113 8

(cancer vs cancer) (normal vs normal)

8- (normal vs normal) 11- cg0441098 (cancer vs cancer) cg00329447

145028170 (cancer+normal vs 70282745 7 (cancer+normal vs

cancer+normal) cancer+normal)

8- 11- cgl449822 (normal vs normal) cg09125300 (normal vs normal)

22447068 70282774 7 (cancer vs cancer) (cancer+normal vs

cancer+normal)

(normal vs normal)

11- cgl404170 (cancer vs cancer)

9-4300203 cgl0836809 (normal vs normal)

70282789 1 (cancer+normal vs

cancer+normal)

9- 12- cg2115662

cgl3985688 (normal vs normal) (normal vs normal)

96709791 10958919 0

9- 12- cg0075204

cg06194070 (normal vs normal) (normal vs normal)

96712772 110785080 7

(cancer vs cancer)

(normal vs normal) (cancer vs cancer)

9- 12- cg0338978 (cancer vs cancer) cg07852402 (normal vs normal)

96713643 117429362 9 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(normal vs normal)

9- 12- cgl872534

cgl4374754 (cancer+normal vs (normal vs normal)

96714295 131493258 8

cancer+normal)

(normal vs normal)

(normal vs normal)

9- cg0247492 (cancer vs cancer) cg22902266 (cancer+normal vs 12-3930923

96714313 6 (cancer+normal vs

cancer+normal)

cancer+normal)

9- 12- cg2403205

cgl0454937 (normal vs normal) (normal vs normal)

96715047 75961704 6

9- (cancer vs cancer) 12- cgl687156

cgl3398482 (normal vs normal)

96715256 (normal vs normal) 98986887 1

(normal vs normal)

9- 13- cg2279534

cg00927495 (normal vs normal) (cancer+normal vs

96715687 111935508 5

cancer+normal)

(normal vs normal)

9- 13- cgl427000 (cancer vs cancer) cgl4316431 (normal vs normal)

96721817 111935521 2 (cancer+normal vs

cancer+normal)

9- 13- cg0361672

cg07184658 (normal vs normal) (normal vs normal)

96722329 112602415 2

9- 13- cg0947336

cgl4428080 (normal vs normal) (normal vs normal)

96723014 112927190 4

(normal vs normal)

9- 14- cg2115675 (cancer vs cancer) cg09155774 (normal vs normal)

96723033 32866773 6 (cancer+normal vs

cancer+normal)

14- cg2051204

Status - Hypo (normal vs normal)

51230329 4

(normal vs normal)

1- 14- cgl206915

cg03962214 (cancer+normal vs (normal vs normal)

10707953 82028411 8

cancer+normal)

(normal vs normal)

1- 15- cg0030685 (cancer vs cancer) cg00647881 (normal vs normal)

153536528 39742079 1 (cancer+normal vs

cancer+normal)

(normal vs normal)

1- 15- cg0805747 (cancer vs cancer) cg27310485 (normal vs normal)

153536563 45803341 5 (cancer+normal vs

cancer+normal)

1- 15- cg0590739

cgl 1580676 (normal vs normal) (normal vs normal)

156211415 56643419 8

(normal vs normal)

15- cgl518971

1-1563500 cg09159050 (normal vs normal) (cancer+normal vs

79723173 5

cancer+normal)

1- (normal vs normal) cg0821432

cg21101726 16-1599072 (normal vs normal)

204124158 (cancer+normal vs 9 cancer+normal)

(normal vs normal)

16- cg0053578 (cancer vs cancer)

1-2142534 cg04597658 (normal vs normal)

49766785 5 (cancer+normal vs

cancer+normal)

16- cg0388067

1-2304315 cg09129839 (normal vs normal) (normal vs normal)

65708104 3

16- cg0668429

1-3626994 cgl7441982 (normal vs normal) (normal vs normal)

73247500 6

16- cg0825092

1-898852 cg03148373 (normal vs normal) (normal vs normal)

88111009 1

10- 16- cg0474769

cgl6993911 (normal vs normal) (normal vs normal)

5638431 88111362 3

11- 17- cg0237214

cg04745079 (normal vs normal) (normal vs normal)

119993751 58966213 4

(normal vs normal)

11- cg2035388

cg26247168 (normal vs normal) 17-663064 (cancer+normal vs

119994722 4

cancer+normal)

11- 17- cgl727846

cgl3962286 (normal vs normal) (normal vs normal)

128813183 76798203 6

(normal vs normal)

11- 17- cgl 183087 (cancer vs cancer) cgl7589284 (normal vs normal)

28422367 78006238 6 (cancer+normal vs

cancer+normal)

11- 18- cg0129578

cg03857384 (normal vs normal) (normal vs normal)

3187777 12437948 5

(normal vs normal)

11- (cancer vs cancer) cgl876324

cgl5718663 2-12907913 (normal vs normal)

3187784 (cancer+normal vs 7

cancer+normal)

11- 2- cgl840625

cg05982473 (normal vs normal) (normal vs normal)

3187803 144995067 5

(normal vs normal)

11- cgl643960

cg24568082 (cancer+normal vs 2-19376860 (normal vs normal)

69151092 8

cancer+normal)

12- 2- cg0531118

cg07274333 (normal vs normal) (normal vs normal)

20193597 217301204 0

12- 2- cg2615205

cg27419119 (normal vs normal) (normal vs normal)

57559901 219994830 1

(normal vs normal)

12- 2- cg2752900 (cancer vs cancer) cg07677157 (normal vs normal)

66050928 237490808 4 (cancer+normal vs

cancer+normal)

13- cg2701516

cg24719241 (normal vs normal) 2-24816070 (normal vs normal)

109803528 1

13- cg2400889

cg02355680 (normal vs normal) 2-39627269 (normal vs normal) 110591252 3

13- cg0296528

cgl2762449 (normal vs normal) 2-39952015 (normal vs normal)

113672808 3

(normal vs normal)

13- cgl701617

cg02381064 (cancer+normal vs 2-98507477 (normal vs normal)

30088771 5

cancer+normal)

13- 20- cgl064028

cgl9968890 (normal vs normal) (normal vs normal)

31747897 13971811 4

(normal vs normal)

(normal vs normal)

14- cg0509789 (cancer vs cancer) cgl0348368 (cancer+normal vs 20-5080743

105851883 9 (cancer+normal vs

cancer+normal)

cancer+normal)

14- 20- cg2303777

cgl3496915 (normal vs normal) (normal vs normal)

34247003 55072651 7

14- cg23660866 (normal vs normal) 22- cg0956136 (normal vs normal) 95009914 45676755 5

15- 22- cgl674471

cg27307975 (normal vs normal) (normal vs normal)

58797839 50445676 0

15- 3- cg2415798

cgl4222307 (normal vs normal) (normal vs normal)

61097246 100270300 2

16- 3- cg2257282

cgl0458734 (normal vs normal) (normal vs normal)

1742021 126554736 0

16- cgl092961

cg06775420 (normal vs normal) 3-45190814 (normal vs normal)

1742245 4

(normal vs normal)

16- cgl871223 (cancer vs cancer) cg05711506 (normal vs normal) 3-57903821

1813796 1 (cancer+normal vs

cancer+normal)

16- cg0937798

cg06095047 (normal vs normal) 3-66798910 (normal vs normal)

31447114 0

(normal vs normal)

16- cgl305011

cg05396425 (cancer+normal vs 3-73503670 (normal vs normal)

4587038 5

cancer+normal)

16- 4- cgl650361

cg04736751 (normal vs normal) (normal vs normal)

7807001 114679761 1

(normal vs normal)

16- 4- cg0358241

cgO 1779679 (cancer+normal vs (normal vs normal)

87857222 177804777 9

cancer+normal)

(normal vs normal)

17- cgl483362

cg09361941 (normal vs normal) 4-54667491 (cancer+normal vs 8128471 6

cancer+normal)

18- cg0551649

cg01288184 (normal vs normal) 4-74487609 (normal vs normal)

20811408 9

2- 5- cg2302220

cgl2535109 (normal vs normal) (normal vs normal)

216708370 107450780 6

(normal vs normal)

2- 5- cg2456659

cg21517506 (cancer+normal vs (normal vs normal)

235242882 137365576 5

cancer+normal)

2- cgl954037

cg27214687 (normal vs normal) 5-13945611 (normal vs normal)

241383517 1

(normal vs normal)

2- cgl568996

cg23574298 (cancer+normal vs 5-14374397 (normal vs normal)

55382186 9

cancer+normal)

2- 5- cg0785819

cgl3659933 (normal vs normal) (normal vs normal)

65839377 177853481 5

(normal vs normal)

20- 5- cgl800909

cg01572549 (cancer+normal vs (normal vs normal)

60926800 177853574 3

cancer+normal)

22- cg0382476

cg03175417 (normal vs normal) 5-5320334 (normal vs normal)

20050298 8

3- cgl842503

cg23471798 (normal vs normal) 5-58412295 (normal vs normal)

110110880 2

(normal vs normal)

(normal vs normal)

3- cg0732411 (cancer vs cancer) cg22607164 (cancer+normal vs 5-80060102

184349562 6 (cancer+normal vs

cancer+normal)

cancer+normal)

(normal vs normal)

3- 6- cg0579814 (cancer vs cancer) cg21090033 (normal vs normal)

196065357 127781063 7 (cancer+normal vs

cancer+normal)

3- 6- cg2723240

cg00779602 (normal vs normal) (normal vs normal)

66002927 127977312 1

(normal vs normal)

3- 6- cg2200477 (cancer vs cancer) cg06109867 (normal vs normal)

66002991 137495354 4 (cancer+normal vs

cancer+normal) (normal vs normal)

4- cgl992766 (cancer vs cancer) cg25209938 (normal vs normal) 6-3150267

183769227 1 (cancer+normal vs cancer+normal)

4- cgl203312

cg26221941 (normal vs normal) 6-32933013 (normal vs normal)

188256637 5

4- cg0282757

cgl6847428 (normal vs normal) 6-34566245 (normal vs normal)

26095438 2

4- cgl 141270

cg00436282 (normal vs normal) 6-44629403 (normal vs normal)

70861449 3

5- cg2302884

cg23475112 (normal vs normal) 6-65214835 (normal vs normal)

131725325 1

(normal vs normal)

cg0073493

5-393347 cgl7287155 (cancer+normal vs 6-9116428 (normal vs normal)

1

cancer+normal)

(normal vs normal)

5- 7- cg0551877

cg08853399 (cancer+normal vs (normal vs normal)

65528850 148730143 8

cancer+normal)

cg2056736

5-912599 cgl4499678 (normal vs normal) 7-27565815 (normal vs normal)

1

cg2320867

5-912821 cgl7510385 (normal vs normal) 7-27595446 (normal vs normal)

8

6- cgl842558

cg00944666 (normal vs normal) 7-37086890 (normal vs normal)

107926037 6

(normal vs normal)

6- cgl542309 (cancer vs cancer) cg26130669 (normal vs normal) 7-39747662

11771473 2 (cancer+normal vs cancer+normal)

(normal vs normal)

6- cg2371936

cgl0301879 (normal vs normal) 8-12594834 (cancer+normal vs

11771680 7

cancer+normal)

6- cg2533525

cg04837722 (normal vs normal) 8-60537981 (normal vs normal)

160463767 8

6- cg2003512

cg05923105 (normal vs normal) 8-80819477 (normal vs normal)

168748492 7

(normal vs normal)

6- (normal vs normal) cgl442752 (cancer vs cancer) cg02840092 9-16204159

168748530 (cancer vs cancer) 8 (cancer+normal vs cancer+normal)

6- ReGiCaG (cancer vs

cg24852883 (normal vs normal)

170560097 cancer)

6- cgl2651173 (normal vs normal) Status - Hyper

31823344

6- cg0901844

cg26867987 (normal vs normal) 1-11539599 (cancer vs cancer)

33131450 4

6- 1- cg0435104

cg04249605 (normal vs normal) (cancer vs cancer)

33131560 165325673 9

cg2192977 (cancer vs cancer)

6-3517953 cg22745369 (normal vs normal) 1-29586580

1 (normal vs normal) cgl081075

6-6894163 cg02096172 (normal vs normal) 1-47691160 (cancer vs cancer)

2

(normal vs normal)

(cancer vs cancer)

cg0958827

6-6971371 cgl9751937 (cancer vs cancer) 1-62784651 (cancer vs cancer)

1

(cancer+normal vs

cancer+normal)

7- 10- cg2385804

cgl3223721 (normal vs normal) (cancer vs cancer)

131720532 11059577 0

10- cg0390801

7-1604448 cgO 1726448 (normal vs normal) (cancer vs cancer)

124895441 5

7-2094977 cg22717323 (normal vs normal) 10- cgl868540 (cancer vs cancer) (cancer+normal vs 124895448 8

cancer+normal)

(normal vs normal)

10- cgl466351

7-4231054 cg03976326 (cancer+normal vs (cancer vs cancer)

124895461 0

cancer+normal)

10- cgl 175735

7-4802535 cgl5247247 (normal vs normal) (cancer vs cancer)

131762052 7

(cancer vs cancer)

10- cg2402237 (cancer vs cancer)

7-5647786 cg01687558 (normal vs normal)

20104497 5 (cancer+normal vs cancer+normal)

(cancer vs cancer)

10- cgl760320

7-6290148 cg23728359 (normal vs normal) (cancer+normal vs

20104935 6

cancer+normal)

(cancer vs cancer)

8- 10- cg0862559 (cancer vs cancer) cg21341817 (normal vs normal)

102019870 20104948 0 (cancer+normal vs cancer+normal)

8- 10- cg2616680

cgl 1313780 (normal vs normal) (cancer vs cancer)

103817950 71812612 4

10- cg0334992

8-1274678 cgl5654779 (normal vs normal) (cancer vs cancer)

71813286 2

10- cg2411378

8-1274686 cg22152500 (normal vs normal) (cancer vs cancer)

79398055 2

(normal vs normal)

8- 10- cgl l59151

cgl 1007190 (cancer+normal vs (cancer vs cancer)

141566084 85954316 6

cancer+normal)

8- 10- cgl667860

cg00293626 (normal vs normal) (cancer vs cancer)

143463227 85954331 2

8- 10- cg0361100

cg25834632 (normal vs normal) (cancer vs cancer)

144590015 85954336 7

(normal vs normal)

8- 11- cgl676449

cgl6888603 (cancer+normal vs (cancer vs cancer)

144696651 117667862 4

cancer+normal)

(normal vs normal)

8- cg0163755

cgl0299941 (cancer+normal vs 12-2161661 (cancer vs cancer)

145009137 1

cancer+normal)

(normal vs normal)

8- 12- cg0912543

cg08159271 (cancer+normal vs (cancer vs cancer)

145009241 21927433 0

cancer+normal)

8- 12- cg2025577 (cancer vs cancer) cg27498434 (normal vs normal)

30556362 48398370 5 (cancer vs cancer)

13- cg0540423

8-337539 cgl5469184 (normal vs normal) (cancer vs cancer)

110437093 6

8- 15- cg0428316 (cancer vs cancer) cg05885688 (normal vs normal)

41628552 29862517 2 (normal vs normal)

(cancer vs cancer)

8- 17- cg2592716 (cancer vs cancer) cg25465344 (normal vs normal)

79713763 17685407 4 (cancer+normal vs cancer+normal)

(cancer vs cancer)

8- 17- cgl590640 (cancer vs cancer) cgO 1822827 (normal vs normal)

99180671 17685582 9 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 17- cgl987229

cg03381604 (normal vs normal) (normal vs normal)

99180740 17686141 9

(cancer+normal vs cancer+normal)

9- 17- cgl967092

cgl3794641 (normal vs normal) (cancer vs cancer)

138289504 43972806 3 9- 17- cgl836801 (cancer vs cancer) cgl4520832 (normal vs normal)

139530300 43972978 9 (cancer vs cancer)

(cancer vs cancer)

GBM LGG (cancer vs 17- cg2743780 (cancer vs cancer) cancer) 48619672 6 (cancer+normal vs cancer+normal) cgl889844

Status - Hyper 17-5974064 (cancer vs cancer)

0

(cancer vs cancer) (cancer vs cancer)

1- 17- cgl451721

cgl8533883 (cancer vs cancer) (normal vs normal)

11919464 75447478 7

(cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 17- cgl810464

cgl6559275 (cancer vs cancer) (normal vs normal)

150522121 75447504 5

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 17- cg0071239

cgl2610832 (cancer+normal vs

27894955 (cancer+normal vs 79373624 0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- cg2336391 (cancer vs cancer) cgl7276002 (cancer+normal vs 17-8055756

75172806 1 (cancer+normal vs cancer+normal)

cancer+normal)

11- 18- cg2012703

cg06285590 (cancer vs cancer) (cancer vs cancer)

119191974 42260234 5

(cancer vs cancer)

11- cg2214145

cgl6628183 (cancer+normal vs 18-7566656 (cancer vs cancer)

126456052 6

cancer+normal)

(cancer vs cancer) l icgl647417

cg07985890 (cancer vs cancer) 18-7566781

es (cancer+normal vs 190999 0

cancer+normal)

11- 19- cg2364185

cgl5676015 (cancer vs cancer) (cancer vs cancer)

67272636 31841161 2

11- 19- cg0054580

cg20513950 (cancer vs cancer) (cancer vs cancer)

72463673 31841391 4

12- 19- cgl520837 (cancer vs cancer) cgl6848054 (cancer vs cancer)

107297551 31841555 5 (cancer vs cancer)

12- 19- cgl298627

cg21334598 (cancer vs cancer) (cancer vs cancer)

117316490 31841559 1

(cancer vs cancer) (cancer vs cancer)

12- (cancer vs cancer) 19- cgl 119977

cg06880239 (normal vs normal)

125670513 (cancer vs cancer) 31841663 0

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

12- 19- cgl571126 (cancer vs cancer) cg01063813 (normal vs normal)

57504948 31841952 8 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- (cancer vs cancer) 19- cg2157467 (cancer vs cancer) cg23079808

6493003 (cancer+normal vs 45656942 5 (cancer+normal vs cancer+normal) cancer+normal)

12- (cancer vs cancer) 19- cgl872356

cgl0452531 (cancer vs cancer)

6493278 (cancer vs cancer) 51228831 0

12- 19- cg2488457 (cancer vs cancer) cg21266616 (cancer vs cancer)

94136549 58661833 2 (cancer vs cancer)

12- cg03861966 (cancer vs cancer) 2- cg2154443 (cancer vs cancer) 94136602 114260879 7

(cancer vs cancer)

(cancer vs cancer)

13- 2- cgl900122

cgl 1997708 (normal vs normal) (cancer vs cancer) 114927854 177053345 6

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

13- (normal vs normal) 2- cg0473912

cg03268893 (cancer vs cancer)

27557503 (cancer+normal vs 177502854 3

cancer+normal)

14- (cancer vs cancer) cg2520613

cgl2930714 2-45395956 (cancer vs cancer)

24835006 (cancer vs cancer) 4

(cancer vs cancer)

14- 21- cg0844866 (cancer vs cancer) cgl0859966 (cancer vs cancer)

24898992 40984780 5 (cancer+normal vs cancer+normal)

14- (cancer vs cancer) 22- cg2679667

cgO 1174771 (cancer vs cancer)

32670315 (cancer vs cancer) 17849639 9

(cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer)

14- 22- cgl659000 (cancer vs cancer) cg02380334 (normal vs normal)

70038925 21319245 5 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

15- 22- cg0796080 (cancer vs cancer) cgl5586327 (cancer vs cancer)

34611057 21319661 6 (cancer+normal vs cancer+normal)

15- 3- cgl069159

cg25489524 (cancer vs cancer) (cancer vs cancer)

65127973 128337033 2

15- 3- cg2147489

cg24977462 (cancer vs cancer) (cancer vs cancer) 65128112 170136489 7

15- 3- cg2138974

cgl2317470 (cancer vs cancer) (cancer vs cancer)

67143691 170136499 3

(cancer vs cancer)

15- (cancer vs cancer) cgl718946

cgl8558647 3-77089110 (cancer+normal vs

93198495 (cancer vs cancer) 5

cancer+normal)

(cancer vs cancer)

16- cg2743879

cg04153495 (cancer vs cancer) 4-13546151 (cancer+normal vs

25078095 8

cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) cg2039332

cg05006755 4-13546169 (cancer vs cancer)

4233246 (cancer+normal vs 4

cancer+normal)

16- 4- cgl733321

cg03300177 (cancer vs cancer) (cancer vs cancer)

56390811 141294016 1

(cancer vs cancer)

16- 4- cg0288628 (cancer vs cancer) cgl0504751 (cancer vs cancer)

56390830 166300290 4 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- 4- cg0059928

cg04313875 (normal vs normal) (cancer vs cancer)

1553202 166300445 0

(cancer+normal vs

cancer+normal)

17- (cancer vs cancer) 4- cgl046932

cgl3180678 (cancer vs cancer)

16256990 (cancer vs cancer) 170947241 9

17- cgl828036

cg05207834 (cancer vs cancer) 4-48988066 (cancer vs cancer)

49199381 2

(cancer vs cancer) (cancer vs cancer)

17- cgl789182

cg00023001 (cancer vs cancer) 4-55524400 (cancer+normal vs

55938748 0

(normal vs normal) cancer+normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- cgl279149 (cancer vs cancer) cg22451358 (normal vs normal) 4-57522094

55938871 2 (cancer vs cancer)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

17- cg2610515

cgl6936953 (cancer+normal vs 4-81951953 (cancer vs cancer)

57915665 6

cancer+normal)

(cancer vs cancer)

17- cg2691767 (cancer vs cancer) cgl2054453 (cancer+normal vs 4-81952024

57915717 3 (cancer vs cancer) cancer+normal)

17- cg2669956

cg06409153 (cancer vs cancer) 4-81952653 (cancer vs cancer)

67323953 9

(cancer vs cancer)

17- 5- cg0468451

cg25038060 (cancer vs cancer) (cancer+normal vs

74497306 121647858 6

cancer+normal)

17- 5- cg2198415

cgl2565681 (cancer vs cancer) (cancer vs cancer)

74497418 121648022 0

19- 5- cg0778103

cg02097309 (cancer vs cancer) (cancer vs cancer)

13266390 134871778 5

(cancer vs cancer)

(cancer vs cancer)

19- 5- cg0462009

cgl0565187 (normal vs normal) (cancer vs cancer)

1468943 134871805 1

(cancer+normal vs

cancer+normal)

19- 5- cg2263075

cg06303772 (cancer vs cancer) (cancer vs cancer)

17717530 134871807 5

(cancer vs cancer)

(cancer vs cancer)

19- 5- cgl474756

cg25814383 (normal vs normal) (cancer vs cancer)

19336240 134871962 3

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) 5- cg0703550

cgl9250790 (cancer vs cancer)

2614086 (cancer+normal vs 134871966 3

cancer+normal)

19- 5- cg0406358

cg26825934 (cancer vs cancer) (cancer vs cancer)

3275913 134871973 9

19- 5- cg0596361

cgl9814309 (cancer vs cancer) (cancer vs cancer)

3275998 159343468 8

(cancer vs cancer)

19- (cancer vs cancer) 5- cg0904967

cg24139898 (cancer vs cancer)

35531817 (cancer+normal vs 159343481 2

cancer+normal)

19- (cancer vs cancer) 5- cg0701117 (cancer vs cancer) cg21484586

35531859 (cancer vs cancer) 159343549 2 (cancer vs cancer)

(cancer vs cancer)

19- 5- cg0871185

cgl 1597497 (cancer+normal vs (cancer vs cancer)

45257305 172756550 8

cancer+normal)

(cancer vs cancer)

19- 5- cgl644386

cgl2536502 (cancer+normal vs (cancer vs cancer)

46142673 172756558 6

cancer+normal)

(cancer vs cancer)

19- 5- cg0729596

cg01544351 (cancer vs cancer) (cancer+normal vs

46142757 175223982 4

cancer+normal)

19- (cancer vs cancer) cgl486857

cg07925085 5-42423718 (cancer vs cancer)

48824622 (cancer vs cancer) 4

19- cgl204258 (cancer vs cancer) cgl8873530 (cancer vs cancer) 5-42423947

49315663 7 (cancer vs cancer) (normal vs normal)

(cancer+normal vs cancer+normal)

(cancer vs cancer)

2- cgl629201

cgl2944530 (cancer vs cancer) 5-42424356 (cancer+normal vs

201982310 6

cancer+normal)

2- cg2477372

cg23869335 (cancer vs cancer) 5-42424525 (cancer vs cancer)

220159595 0

(cancer vs cancer)

(cancer vs cancer)

2- (normal vs normal) cgl009614

cgl 1702456 6-17281838 (cancer+normal vs

231280907 (cancer+normal vs 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cg2442887

cg02001779 (cancer vs cancer) 6-21664652 (normal vs normal)

231281264 7

(cancer+normal vs cancer+normal)

2- 7- cg2076711

cg07158434 (cancer vs cancer) (cancer vs cancer)

232571157 155249648 1

2- cg0865091

cgl9622755 (cancer vs cancer) 7-20817530 (cancer vs cancer)

47169299 0

2- (cancer vs cancer) cgl542790

cgl8998670 7-20825216 (cancer vs cancer)

58273552 (cancer vs cancer) 6

20- cg0772847

cg26705720 (cancer vs cancer) 7-6655711 (cancer vs cancer)

10652787 9

(cancer vs cancer)

3- 8- cg0441389 (normal vs normal) cgl0678427 (cancer vs cancer)

127176163 105601615 5 (cancer+normal vs

cancer+normal)

3- (cancer vs cancer) cg2149370

cg22481960 8-6691879 (cancer vs cancer)

13008800 (cancer vs cancer) 3

3- 9- cgl890434

cgl7701886 (cancer vs cancer) (cancer vs cancer)

182970833 126773656 6

3- 9- cgl075597

cgl9455322 (cancer vs cancer) (cancer vs cancer)

46735335 126773879 3

3- cg25104512 (cancer vs cancer) Status - Hypo

46735454

1- cgl016112

4-1006237 cgl7105609 (cancer vs cancer) (cancer vs cancer)

172628020 1

1- cgl500781

4-1006270 cg20564913 (cancer vs cancer) (cancer vs cancer)

178061518 3

1- cg2160695

4-1006278 cg05866411 (cancer vs cancer) (cancer vs cancer)

184211934 6

4- 1- cg0781796

cg04212922 (cancer vs cancer) (cancer vs cancer)

141173867 184721222 7

cgl690361

4-3464874 cg25237365 (cancer vs cancer) 1-28111716 (cancer vs cancer)

8

5- cgl457579

cg04597532 (cancer vs cancer) 10-3984975 (cancer vs cancer)

138897363 0

5- 10- cg0886655 (cancer vs cancer) cgl0642240 (cancer vs cancer)

139126512 49647167 7 (cancer vs cancer)

5- 10- cg2379939

cg25412017 (cancer vs cancer) (cancer vs cancer)

175560449 60588674 3

6- (cancer vs cancer) 10- cg0549853

cg04671145 (cancer vs cancer)

157041096 (cancer vs cancer) 88719848 9

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

6- 10- cg2045923 (cancer vs cancer) cg08501292 (normal vs normal)

25962987 88719950 8 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

6- cg05552183 (cancer vs cancer) 10- cg0709209 (normal vs normal) 42928497 (normal vs normal) 88720025 7 (cancer vs cancer)

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 10- cg0424837

cg23514619 (normal vs normal) (cancer vs cancer)

43237330 97145431 3

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 10- cg2721576 (normal vs normal) cg20434586 (normal vs normal)

43237511 98425148 8 (cancer vs cancer)

(cancer+normal vs

cancer+normal)

6- (cancer vs cancer) 11- cgl606165 (cancer vs cancer) cg09681335

74233510 (cancer vs cancer) 115088907 6 (cancer vs cancer)

7- (cancer vs cancer) 11- cg2689062

cgl 1347411 (cancer vs cancer)

150020925 (cancer vs cancer) 72982996 1

7- (cancer vs cancer) 11- cg2488147

cg06980547 (cancer vs cancer)

22894557 (cancer vs cancer) 94248604 2

7- 12- cg2124965

cgl9089073 (cancer vs cancer) (cancer vs cancer)

74020924 10324843 9

7- 12- cg2168577

cgl9105122 (cancer vs cancer) (cancer vs cancer)

75896889 10324918 0

7- 12- cgl609546

cgl7222941 (cancer vs cancer) (cancer vs cancer)

77648567 24228975 4

7- 12- cg2021529

cgl0271408 (cancer vs cancer) (cancer vs cancer)

77648600 32831428 0

7- 12- cg2738722

cg04976780 (cancer vs cancer) (cancer vs cancer)

77649540 32831504 2

(cancer vs cancer)

7- 12- cgl843689 (cancer vs cancer) cg01914455 (cancer vs cancer)

77649564 47471907 8 (cancer+normal vs

cancer+normal)

8- (cancer vs cancer) 12- cgl561833

cg24115571 (cancer vs cancer)

104310713 (cancer vs cancer) 52182759 6

8- 12- cg0378222

cg25834419 (cancer vs cancer) (cancer vs cancer)

110656442 54985731 0

8- 13- cg2525225

cg00447052 (cancer vs cancer) (cancer vs cancer)

145556707 113544125 5

8- 13- cg2228673

cg06829538 (cancer vs cancer) (cancer vs cancer)

21906349 113544293 2

8- (cancer vs cancer) 13- cg0014144

cg01725531 (cancer vs cancer)

23082789 (cancer vs cancer) 113544658 7

(cancer vs cancer)

8- (cancer vs cancer) 14- cgl896021

cg08305799 (cancer vs cancer)

30580804 (cancer+normal vs 23285365 8

cancer+normal)

9- 14- cgl219937

cgl3668544 (cancer vs cancer) (cancer vs cancer)

132646821 67881521 6

9- 14- cgl670113

cgl4242528 (cancer vs cancer) (cancer vs cancer)

33166541 75747961 3

9- 15- cg2390801

cg20263942 (cancer vs cancer) (cancer vs cancer)

88714961 28263701 9

15- cgl989053

Status - Hypo (cancer vs cancer)

28263706 3

(normal vs normal)

(cancer vs cancer)

1- 15- cg2344101 (cancer vs cancer) cg27508545 (cancer vs cancer)

10240017 34657364 8 (cancer vs cancer)

(cancer+normal vs

cancer+normal)

1- cg23661000 (normal vs normal) 15- cg0345387 (cancer vs cancer) 10240025 (cancer vs cancer) 39563291 0

(cancer vs cancer)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

15- cg2398749

1-2006465 cg06791083 (cancer+normal vs (cancer vs cancer)

43822292 1

cancer+normal)

(cancer vs cancer) 15- cgl358000

1-3128606 cg22031783 (cancer vs cancer)

(cancer vs cancer) 57626444 2

(normal vs normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 15- cg2242336

cg09506001 (cancer vs cancer)

36559506 (cancer+normal vs 65042722 3

(cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) 15- cgl486499

1-6390793 cg00081799 (cancer vs cancer)

(cancer vs cancer) 69563432 9

(cancer vs cancer)

1- 15- cg0916420

cg26912671 (cancer+normal vs (cancer vs cancer)

66458803 70786271 6

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 15- cgl932238 (cancer vs cancer)

1-9448660 cgl2658495

(cancer+normal vs 99408636 0 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer) cg0530879 (cancer vs cancer) cg01467532 16-1578807

115738883 (cancer+normal vs 2 (cancer vs cancer) cancer+normal)

(normal vs normal)

(cancer vs cancer)

16- cg0436271

10-405225 cg20595750 (cancer vs cancer) (cancer vs cancer)

88564247 1

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

16- cg0524249

10-405362 cgl8074403 (cancer+normal vs (cancer vs cancer)

88575349 4

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 17- cgl 186077

10-661009 cgl9926144 (cancer vs cancer)

(cancer+normal vs 38609504 7

cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) 17- cgl987807

cg23871994 (cancer vs cancer)

113577434 (cancer+normal vs 38609634 6

cancer+normal)

(normal vs normal)

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) cgl347607

cg07737063 17-767301 (cancer vs cancer)

1486341 (cancer+normal vs 8

(cancer+normal vs cancer+normal)

cancer+normal)

12- (cancer vs cancer) 18- cg2761453

cg03061518 (cancer vs cancer)

123738291 (cancer vs cancer) 56296496 4

12- (cancer vs cancer) 18- cg2540707

cgl7429587 (cancer vs cancer)

124905230 (cancer vs cancer) 56296544 7

(cancer vs cancer) (cancer vs cancer)

12- (cancer vs cancer) 19- cgl933822 (cancer vs cancer) cg23617848

131452297 (cancer+normal vs 39052032 2 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) 19- cgl967337

cg24211304 (cancer vs cancer)

4596426 (cancer+normal vs 55721180 6

cancer+normal)

12-656703 cg03539204 (cancer vs cancer) 19- cgl964183 (cancer vs cancer) (cancer vs cancer) 57105832 9

(cancer+normal vs

cancer+normal)

13- 2- cgl473044

cgl0628699 (cancer vs cancer) (cancer vs cancer)

103531040 106960893 9

(cancer vs cancer)

13- 2- cgl620053

cg22954906 (cancer vs cancer) (cancer+normal vs

103531058 135532566 1

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

13- 2- cg2321257 (cancer vs cancer) cg26951340 (cancer vs cancer)

111893537 219256018 9 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) 2- cg2736688

cg06206670 (cancer vs cancer)

113436564 (cancer+normal vs 224993012 8

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- (cancer vs cancer) cgl 167277 (cancer vs cancer) cgl4737571 2-75078286

113436568 (cancer+normal vs 2 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) cg2678430 (cancer vs cancer) cg03010009 2-8596908

80585265 (cancer+normal vs 0 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) cgl 144407

cg03403507 2-9427798 (cancer vs cancer)

32798387 (cancer+normal vs 2

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 21- cg0197570

cg24812523 (cancer vs cancer)

32798762 (cancer+normal vs 27015734 6

cancer+normal)

14- (cancer vs cancer) 21- cg2701920 (cancer vs cancer) cgl8459806

51293793 (cancer vs cancer) 46323665 1 (cancer vs cancer)

(cancer vs cancer)

14- (cancer vs cancer) 22- cgl 122926

cg24158307 (cancer vs cancer)

95599667 (cancer+normal vs 23519916 7

cancer+normal)

15- (cancer vs cancer) 3- cgl l81683

cgl3191951 (cancer vs cancer)

71685353 (cancer vs cancer) 150484093 8

(normal vs normal)

(cancer vs cancer)

16- 3- cgl247951

cg00900231 (cancer vs cancer) (cancer vs cancer)

50897271 175987813 2

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

16- 3- cgl098528 (cancer vs cancer) cg02619656 (cancer vs cancer)

72460083 194573301 1 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(normal vs normal) (normal vs normal) (cancer vs cancer) (cancer vs cancer)

16- 3- cg2193737

cg05347108 (cancer vs cancer) (cancer vs cancer)

72460114 194868750 7

(cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) 3- cg2185633

cg00319595 (cancer vs cancer)

75300861 (cancer+normal vs 196754664 4

cancer+normal)

16- cg03551062 (cancer vs cancer) 3- cg0606945 (cancer vs cancer) 88041289 (cancer vs cancer) 196754722 7

(cancer+normal vs

cancer+normal)

(normal vs normal)

16- (cancer vs cancer) cg2592154

cg01279418 3-59980762 (cancer vs cancer)

89623374 (cancer+normal vs 3

cancer+normal)

(normal vs normal)

17- (cancer vs cancer) cg0762731

cgl3691567 3-61517101 (cancer vs cancer)

1308616 (cancer+normal vs 7

cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- 4- cg2036730

cg00145352 (cancer vs cancer) (cancer vs cancer)

2319906 154391944 4

(cancer+normal vs

cancer+normal)

(normal vs normal) (normal vs normal)

17- (cancer vs cancer) cg2660504 (cancer vs cancer) cgl8232597 4-2439731

29624396 (cancer+normal vs 6 (cancer+normal vs cancer+normal) cancer+normal)

17- 5- cg0336943

cgl8473137 (cancer vs cancer) (cancer vs cancer)

30815034 179442399 2

17- (cancer vs cancer) cg2280843

cg06405341 5-37772265 (cancer vs cancer)

63535223 (cancer vs cancer) 5

(cancer vs cancer)

17- (cancer vs cancer) cg2545581

cg00711291 5-77072789 (cancer vs cancer)

71345538 (cancer+normal vs 1

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- 6- cg2558144 (cancer vs cancer) cgl9272238 (cancer+normal vs

76220898 106582669 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cg0388709

cg07366188 6-1080885 (cancer vs cancer)

76220929 (cancer+normal vs 2

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 6- cgl484085

cgl0070788 (cancer vs cancer)

76220955 (cancer+normal vs 161636502 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- (cancer vs cancer) 6- cg0332975 (cancer vs cancer) cgl2130672

9151012 (cancer+normal vs 167189272 5 (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

18- 6- cg2349232

cg22291942 (cancer vs cancer) (cancer vs cancer)

32398181 168562318 7

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

18- 6- cgl089660 (cancer vs cancer) cg03722909 (cancer vs cancer)

42324965 168594903 9 (cancer vs cancer)

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

18- 6- cg0806238 (cancer vs cancer) cg07015525 (cancer vs cancer)

42325086 168684757 7 (cancer vs cancer)

(cancer+normal vs

cancer+normal)

19- (cancer vs cancer) 6- cg0284009 (normal vs normal) cg27172769

1255283 (cancer+normal vs 168748530 2 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cg2406715

cg24300446 6-30956397 (cancer vs cancer)

1255516 (cancer+normal vs 0

cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cgl801580

cgl5080870 6-47202254 (cancer vs cancer)

47770746 (cancer+normal vs 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- (cancer vs cancer) cg2155200 (cancer vs cancer) cg22764497 6-47202394

236716219 (cancer+normal vs 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cg0381487

cg06694561 6-7541066 (cancer vs cancer)

236716285 (cancer+normal vs 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- (cancer vs cancer) cgl245803 (cancer vs cancer) cg06747919 7-210075

236716372 (cancer+normal vs 9 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cg2363572

cg00746446 7-33765409 (cancer vs cancer)

23879137 (cancer+normal vs 8

cancer+normal)

2- (cancer vs cancer) cg2269571

cg09675853 7-36607476 (cancer vs cancer)

239306169 (cancer vs cancer) 1

(normal vs normal)

(cancer vs cancer)

2- cg0409915

cg06257052 (cancer vs cancer) 7-40566521 (cancer vs cancer)

240117222 8

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl339232

cg20853370 7-40788535 (cancer vs cancer)

240117640 (cancer+normal vs 0

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl529190

cg00073794 7-41741671 (cancer vs cancer)

30041338 (cancer+normal vs 5

cancer+normal)

(normal vs normal)

(cancer vs cancer)

cgl476912

2-3292757 cg03025986 (cancer vs cancer) 7-98722470 (cancer vs cancer)

1

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 8- cg2396399

2-3480658 cg05777919 (cancer vs cancer)

(cancer+normal vs 102381050 5

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) 8- cg0093423

cg04768463 (cancer vs cancer)

55174473 (cancer+normal vs 104185332 2

cancer+normal)

(normal vs normal) (cancer vs cancer)

2- (cancer vs cancer) 8- cg0188657

cg00820405 (cancer vs cancer)

97213642 (cancer vs cancer) 123966105 0

(cancer+normal vs cancer+normal)

20- (cancer vs cancer) 8- cgl816570

cg04316905 (cancer vs cancer) 5985495 (cancer vs cancer) 142189543 7

22- cgl2894883 (normal vs normal) 8-2037954 cgl273800 (cancer vs cancer) 22288473 (cancer vs cancer) 8

(cancer vs cancer)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

22- (cancer vs cancer) cgl l60915

cg00489795 8-81441781 (cancer vs cancer) 24041104 (cancer+normal vs 6

cancer+normal)

(cancer vs cancer)

22- (cancer vs cancer) cgl519509

cg26799416 8-98868006 (cancer vs cancer) 42611379 (cancer+normal vs 7

cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) SARC (cancer vs

cgl2678686

127327369 (cancer+normal vs cancer)

cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer)

cgl9272592 Status - Hyper

129408521 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (cancer vs cancer) 1- cg2763667

cg03320743 (cancer+normal vs

147657586 (cancer+normal vs 165322606 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (cancer vs cancer) 1- cgl031553

cg20224111 (cancer+normal vs

195616361 (cancer+normal vs 165322784 3

cancer+normal) cancer+normal)

(cancer vs cancer)

3- 1- cg2652259

cg25680629 (cancer vs cancer) (cancer+normal vs

33188872 165323232 2

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

4- 1- cg2430461

cg01578875 (cancer vs cancer) (cancer+normal vs

146804010 169079632 7

(cancer+normal vs cancer+normal) cancer+normal)

4- (cancer vs cancer) 1- cg2414651

cg05701706 (cancer vs cancer)

147187180 (cancer vs cancer) 183155097 8

(normal vs normal)

(cancer vs cancer)

4- 1- cg0194999

cgl0569820 (cancer vs cancer) (cancer vs cancer)

24982540 183155116 3

(cancer+normal vs

cancer+normal)

4- (cancer vs cancer) 1- cg0592901

cg26784682 (cancer vs cancer)

39064477 (cancer vs cancer) 183155154 9

(cancer vs cancer)

5- (cancer vs cancer) 1- cg0421889

cg06612355 (cancer vs cancer)

102834858 (cancer+normal vs 183155366 9

cancer+normal)

5- 1- cg2234646

cgOl 156295 (cancer vs cancer) (cancer vs cancer)

138211184 183155573 1

5- (cancer vs cancer) 10- cg0845183

cgl 1830096 (cancer vs cancer)

140865433 (cancer vs cancer) 119310964 2

(cancer vs cancer)

5- 10- cg2500623

cgl0519882 (cancer+normal vs (cancer vs cancer)

179494929 77163983 1

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

5- 11- cg2745728

cg09645993 (cancer vs cancer) (cancer+normal vs

77289836 35439994 4

(cancer+normal vs cancer+normal) cancer+normal) (normal vs normal)

(cancer vs cancer) (cancer vs cancer)

6- 11- cg2418332

cg24574819 (cancer vs cancer) (cancer+normal vs

102224868 35440062 4

(cancer+normal vs cancer+normal) cancer+normal)

6- (cancer vs cancer) 11- cg2494410

cgO 1080927 (cancer vs cancer)

125341187 (cancer vs cancer) 35440136 9

(cancer vs cancer)

6- (cancer vs cancer) 11- cg2350196

cgl7596249 (cancer vs cancer)

157493773 (cancer+normal vs 35440252 2

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 11- cg0465352

cgl4549524 (cancer vs cancer)

24140822 (cancer+normal vs 87908631 2

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 12- cg0857329

cg08908855 (cancer vs cancer)

24140899 (cancer+normal vs 70758965 5

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

7- 13- cg2601516

cg06010390 (cancer vs cancer) (cancer+normal vs

101849120 37838311 3

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- (cancer vs cancer) 13- cg0229783

cg01234984 (cancer+normal vs

101849473 (cancer+normal vs 92002454 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- (cancer vs cancer) 15- cgl982313

cgl 1895696 (cancer+normal vs

105283982 (cancer+normal vs 99559002 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 16- cg0171917

7-4747216 cg01275887 (cancer vs cancer)

(cancer+normal vs 29296693 9

cancer+normal)

(cancer vs cancer) 16- cg2351512

7-4747261 cg07076109 (cancer vs cancer)

(cancer vs cancer) 29296704 5

(cancer vs cancer)

(cancer vs cancer) 16- cg0730132

7-5535692 cg09286367 (cancer+normal vs

(cancer vs cancer) 85648263 9

cancer+normal)

(cancer vs cancer)

8- 16- cg0709964

cg00470636 (cancer+normal vs (cancer vs cancer)

26440349 88292973 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- (cancer vs cancer) 16- cgl470507

cg02712949 (cancer+normal vs

87570714 (cancer+normal vs 88292996 9

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

17- cg0697602

8-9260354 cgl0359460 (cancer vs cancer) (cancer+normal vs

77810742 5

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) cgl l21488

8-9537322 cgl0419849 18-597111 (cancer vs cancer)

(cancer+normal vs 9

cancer+normal)

9- (cancer vs cancer) 19- cg2696089

cgl4554539 (cancer vs cancer)

130854713 (cancer vs cancer) 44270892 6

9- (cancer vs cancer) 19- cgl033883 (cancer vs cancer)

_C gl4494733

139410910 (cancer vs cancer) 48833410 0 (cancer+normal vs cancer+normal)

(normal vs normal)

(cancer vs cancer)

9- 19- cg0635054

cgl4155501 (cancer vs cancer) (cancer vs cancer)

99264127 48833535 4

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer+normal vs 19- cgl731521

(cancer+normal vs cancer+normal) 48833559 9

cancer+normal)

2- cg2531746 (cancer vs cancer)

Status - Hyper

119608121 0 (normal vs normal)

(normal vs normal) (cancer vs cancer)

1- 2- cg2443018

cg04308687 (cancer+normal vs (cancer+normal vs

100231682 128173685 9

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (normal vs normal) 2- cg0247360

cgl7935811 (cancer+normal vs

12678641 (cancer+normal vs 128173750 0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (normal vs normal) 2- cgl010743

cg01346152 (cancer+normal vs

12678761 (cancer+normal vs 177021899 4

cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 2- cg2570832

cg02902865 (cancer+normal vs

12679132 cancer+normal) 177022056 8

cancer+normal)

(normal vs normal) (cancer vs cancer)

1- 2- cgl833877

cg03317045 (cancer+normal vs (cancer+normal vs

175161069 177022121 5

cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 2- cg0566941

cg23037321 (cancer+normal vs

181003203 cancer+normal) 177022962 8

cancer+normal)

(normal vs normal) (cancer vs cancer)

1- 2- cg0978493

cg22705746 (cancer+normal vs (cancer+normal vs

203320506 177023062 4

cancer+normal) cancer+normal)

1- (cancer+normal vs 2- cgl009888

cg27387030 (cancer vs cancer)

203320541 cancer+normal) 227665799 8

1- (cancer+normal vs 2- cgl357251

cgl2624197 (cancer vs cancer)

20698023 cancer+normal) 227665840 1

(cancer vs cancer)

1- (normal vs normal) 2- cg2360139

cgl0985914 (cancer vs cancer)

212769641 (cancer+normal vs 227665895 7

cancer+normal)

(normal vs normal) (cancer vs cancer)

1- cg0602379

cgl 1526198 (cancer+normal vs 20-3653555 (cancer+normal vs

23854847 1

cancer+normal) cancer+normal)

1- (cancer+normal vs 20- cg0276784 (cancer vs cancer) cgl7094249

24867657 cancer+normal) 45986173 1 (normal vs normal)

(cancer vs cancer)

1- (cancer vs cancer) 20- cg2308534

cgl2610832 (cancer vs cancer)

27894955 (cancer+normal vs 50159160 3

cancer+normal)

1- (cancer+normal vs 22- cgl711993

cg23715749 (cancer vs cancer)

37413867 cancer+normal) 20785765 0

(cancer vs cancer)

1- (cancer+normal vs 3- cg0345817

cgl9680850 (cancer+normal vs

37943106 cancer+normal) 157815672 2

cancer+normal)

(cancer vs cancer)

1- (cancer+normal vs 3- cg0540176

cgl7888086 (cancer+normal vs

37945057 cancer+normal) 157815808 4

cancer+normal)

1- (cancer vs cancer) 3- cg0909522 (cancer vs cancer) cgl5687600

59280952 (normal vs normal) 157816094 2 (normal vs normal) (cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (normal vs normal) 3- cg0008948

cg03611060 (cancer+normal vs

59281067 (cancer+normal vs 157816330 6

cancer+normal) cancer+normal)

1- (cancer+normal vs 3- cgl572615

cg23075983 (cancer vs cancer)

59281540 cancer+normal) 157817678 4

1- (cancer+normal vs 4- cgO 174786

cgl6711650 (cancer vs cancer)

61039539 cancer+normal) 174457371 2

(normal vs normal)

1- 4- cg2495023

cgl3938909 (cancer+normal vs (cancer vs cancer)

89873226 174457944 3

cancer+normal)

(normal vs normal)

10- 4- cgl909592

cgl6485048 (cancer+normal vs (cancer vs cancer)

13749193 174458819 0

cancer+normal)

(cancer vs cancer)

10- (cancer+normal vs 4- cg0439208

cg00524374 (cancer+normal vs

3894968 cancer+normal) 186732926 2

cancer+normal)

(normal vs normal) (cancer vs cancer)

10- 4- cg0279030

cg02076355 (cancer+normal vs (cancer+normal vs

45474372 186732932 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 4- cg2678534

cgl7276002 (cancer+normal vs (cancer+normal vs

75172806 186732936 6

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 4- cg0193307

cgl6628183 (cancer+normal vs (cancer vs cancer)

126456052 186732942 3

cancer+normal)

(cancer vs cancer)

12- (cancer+normal vs 4- cgl392144

cgl6881676 (cancer+normal vs

49659619 cancer+normal) 186733024 4

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- 4- cg0434826

cg01063813 (normal vs normal) (cancer vs cancer)

57504948 186733060 5

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) 5- cgl882982

cg23079808 (cancer vs cancer)

6493003 (cancer+normal vs 122422500 7

cancer+normal)

(cancer vs cancer)

12- 5- cg0230058

cgl4947547 (cancer+normal vs (cancer vs cancer)

6493495 122423615 4

cancer+normal)

(normal vs normal)

12- 5- cgl063220

cg25671716 (cancer+normal vs (cancer vs cancer)

96441714 122434544 9

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- 5- cg0012956

cgl 1997708 (normal vs normal) (cancer vs cancer) 114927854 122434853 3

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- (normal vs normal) 5- cg0136005

cg03268893 (cancer+normal vs

27557503 (cancer+normal vs 122434944 4

cancer+normal) cancer+normal)

(cancer vs cancer)

13- 5- cgO 180466

cg02632314 (cancer+normal vs (cancer vs cancer) 41593416 149669414 4

cancer+normal)

14- (cancer+normal vs cg0033571

cgl3564459 5-90575459 (cancer vs cancer)

62004353 cancer+normal) 5

14- cg02380334 (cancer vs cancer) 6-1607922 cgl839805 (cancer vs cancer) 70038925 (cancer vs cancer) 6 (cancer+normal vs

(normal vs normal) cancer+normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer)

(normal vs normal) 6- cgl758625

cgl4539393

70038949 (cancer+normal vs

(cancer+normal vs 170598215 6

cancer+normal) cancer+normal)

15- (cancer vs cancer)

(cancer+normal vs cg0133720

cgl9635897

33360195 6-32063835

cancer+normal) (cancer+normal vs

7

cancer+normal)

15- (cancer vs cancer)

(cancer+normal vs cg2626642

cgl2476968

34610829 6-32063838 (cancer+normal vs cancer+nomial) 7

cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer) cg0752491

cg21610221

93722499 (cancer+normal vs 6-32063901 (cancer+normal vs

9

cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) cg0087298

cgl0060338

20774960 (cancer+normal vs 6-32063991 (cancer+normal vs

4

cancer+normal) cancer+normal)

16- (cancer+normal vs cg0851650

cgl0078415

20775011 6-32064206 (cancer vs cancer) cancer+nomial) 7

16- (cancer vs cancer)

(cancer+normal vs cg0148511

cg00394823

20775166 6-32064677 (cancer+normal vs cancer+normal) 7

cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer)

(cancer vs cancer) cg2708134

cg05006755

4233246 6-32064692 (cancer+normal vs

(cancer+normal vs 6

cancer+normal) cancer+nomial)

(cancer vs cancer)

16- (cancer vs cancer) cgl579332

cg08554257

50730737 (cancer+normal vs 6-32064749 (cancer+normal vs

9

cancer+normal) cancer+normal)

(cancer vs cancer)

16-744328 cg2128966

cg05542681 (cancer+normal vs 6-32064764 (cancer vs cancer)

9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16-744939 cg0347435

cg04005677 (cancer+normal vs 6-45387347

0 (cancer+normal vs cancer+nomial) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (normal vs normal)

16-745663 cg2635828

cg02958327 6-45387395 (cancer+normal vs

(cancer+normal vs 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

16-745687 cg0868782

cg07482202 6-84221752 (cancer vs cancer)

(cancer+normal vs 5

cancer+nomial)

16- (cancer+normal vs cg2556069

cg27507473

86002958 6-85481532 (cancer vs cancer) cancer+normal) 6

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer)

7- cg2610098

cg04313875 (normal vs normal)

1553202 (cancer+normal vs

100202882 6

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

17- (cancer vs cancer)

7- cg2568048

cg03026373

36715787 (cancer+normal vs (cancer+normal vs

100203114 6

cancer+nomial) cancer+normal)

(normal vs normal)

17- 7- cg0616163

cgl0712561

42392983 (cancer+normal vs (cancer vs cancer)

143106114 0

cancer+normal)

17- (cancer vs cancer) 7- cg2742622

cg00023001

55938748 (cancer vs cancer) (cancer vs cancer)

143106126 0 (normal vs normal)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- 7- cg0237670

cg22451358 (normal vs normal) (cancer vs cancer)

55938871 143106130 3

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

17- (cancer+normal vs 8- cg0545805

cg06452419 (cancer+normal vs

55938940 cancer+normal) 102503892 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 8- cg2034218

cgl6936953 (cancer+normal vs (cancer+normal vs

57915665 102503970 4

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 8- cgl643577

cgl2054453 (cancer+normal vs (cancer vs cancer)

57915717 102504447 9

cancer+normal)

17- (cancer+normal vs 8- cg2563941

cg01409343 (cancer vs cancer)

57915740 cancer+normal) 102504621 5

17- (cancer+normal vs cg0943097

cgl8942579 8-25907314 (cancer vs cancer)

57915773 cancer+normal) 6

(cancer vs cancer)

17- cg0424435

cgl l963912 (cancer+normal vs 8-25908279 (cancer vs cancer)

72439044 4

cancer+normal)

(cancer vs cancer)

19- (normal vs normal) cgl988962

cg06615719 8-26047996 (cancer vs cancer)

1455513 (cancer+normal vs 6

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- cg0555203

cgl0565187 (normal vs normal) 8-37699239 (cancer vs cancer)

1468943 5

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- cgl286933

cg25814383 (normal vs normal) 8-37699360 (cancer vs cancer)

19336240 4

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- (cancer vs cancer) cg2452394

cgl9250790 8-72916620 (cancer+normal vs

2614086 (cancer+normal vs 8

cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) 9- cg0007004

cg24139898 (cancer vs cancer)

35531817 (cancer+normal vs 133308594 2

cancer+normal)

(cancer vs cancer)

19- (normal vs normal) 9- cgl436263

cgl0369688 (cancer vs cancer)

39898283 (cancer+normal vs 133308669 0

cancer+normal)

(cancer vs cancer)

19- 9- cgl349697

cgl 1597497 (cancer+normal vs (cancer vs cancer)

45257305 133308888 9

cancer+normal)

19- (cancer+normal vs

cg08831348 Status - Hypo

46142212 cancer+normal)

(normal vs normal)

19- 1- cg2431118

cg03096975 (cancer+normal vs (cancer vs cancer)

46142574 116610397 2

cancer+normal)

(normal vs normal)

19- 1- cg0054403

cg07804711 (cancer+normal vs (cancer vs cancer)

46142647 118239410 2

cancer+normal) (cancer vs cancer) (cancer vs cancer)

19- 1- cg0826480

cgl2536502 (cancer+normal vs (cancer+normal vs

46142673 155291224 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- cg0823171

cg23533683 (cancer+normal vs 1-1566687 (cancer+normal vs

46144774 0

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

2- 1- cgl049343

cg09456094 (cancer+normal vs (cancer+normal vs

231280878 161168957 6

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (normal vs normal) 1- cg2466485

cgl 1702456 (cancer vs cancer)

231280907 (cancer+normal vs 161676266 5

cancer+normal)

(normal vs normal) (cancer vs cancer)

2- 1- cg0992248

cg05091653 (cancer+normal vs (cancer+normal vs

231281474 168698463 1

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer+normal vs 1- cg2126684

cg08836542 (cancer+normal vs

28618831 cancer+normal) 168698479 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- 1- cg0263372

cg24467337 (cancer+normal vs (cancer+normal vs 31262314 172113506 9

cancer+normal) cancer+normal)

(normal vs normal)

(normal vs normal)

20- 1- cg2521496 (cancer vs cancer) cg07668993 (cancer+normal vs

43883307 172113756 6 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

20- (cancer+normal vs 1- cg2400214

cgl 1368502 (cancer+normal vs 61447490 cancer+normal) 172113920 9

cancer+normal)

(normal vs normal) (cancer vs cancer)

22- 1- cg2145088

cg07713361 (cancer+normal vs (cancer+normal vs 36649144 172114047 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- 1- cgl717822

cgl5038811 (cancer+normal vs (cancer+normal vs

28283857 172114068 0

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

3- 1- cg0332205

cgl3519902 (cancer+normal vs (cancer+normal vs

50639079 172114419 7

cancer+normal) cancer+normal)

(normal vs normal)

4- 1- cg2253437

cg07174665 (cancer+normal vs (cancer vs cancer)

129474594 201511610 4

cancer+normal)

(normal vs normal)

4- cg0031280

cgl7521583 (cancer+normal vs 1-2028213 (cancer vs cancer)

129474618 9

cancer+normal)

(normal vs normal)

1- cg0641926

4-809452 cg24464265 (cancer+normal vs (cancer vs cancer)

206879950 8

cancer+normal)

4- (cancer+normal vs 1- cg0412806

cgl 1468363 (cancer vs cancer)

87857418 cancer+normal) 229733305 5

(normal vs normal)

5- cg0998999

cg01065586 (cancer+normal vs 1-753376 (cancer vs cancer)

52404911 6

cancer+normal)

6- (cancer+normal vs cgl710814

cg07336872 1-86044230 (cancer vs cancer)

150393535 cancer+normal) 1

6- (cancer+normal vs 10- cgl571965

cg21119074 (cancer vs cancer)

20211654 cancer+normal) 124254860 2

(cancer vs cancer)

(cancer vs cancer)

6- 10- cg0365466

cg08501292 (normal vs normal) (cancer vs cancer)

25962987 14551049 8

(cancer+normal vs

cancer+normal) (cancer vs cancer)

6- (normal vs normal) 10- cg2730451

cg06153893 (cancer vs cancer)

25963109 (cancer+normal vs 14551091 9

cancer+normal)

(cancer vs cancer)

6- (normal vs normal) 10- cg0125338

cg21844956 (cancer vs cancer)

25963442 (cancer+normal vs 14551178 6

cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 10- cgl089451

cgl0563645 (cancer+normal vs

31705988 cancer+normal) 90712478 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

6- cg0351209

cg23514619 (normal vs normal) 11-2730129 (cancer+normal vs

43237330 8

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

6- 11- cgl373483

cg20434586 (normal vs normal) (cancer+normal vs

43237511 68779817 3

(cancer+normal vs cancer+normal) cancer+normal)

7- (cancer+normal vs 11- cgl808081

cg22202558 (cancer vs cancer)

101500303 cancer+normal) 70505972 9

(cancer vs cancer)

(cancer vs cancer)

8- (cancer vs cancer) cgl 183069

cg08305799 12-2289797 (cancer+normal vs

30580804 (cancer+normal vs 4

cancer+normal) cancer+normal)

8- (cancer+normal vs 13- cgl049057

cg07773510 (cancer vs cancer)

65293126 cancer+normal) 30009956 7

(cancer vs cancer)

8- 13- cgl 176009

cg06107816 (cancer+normal vs (cancer vs cancer)

80803365 30096184 9

cancer+normal)

(cancer vs cancer)

13- cgl276203

Status - Hypo (cancer+normal vs

73833939 9

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

1- 14- cgl422566

cg27508545 (cancer vs cancer) (cancer+normal vs

10240017 102394448 5

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

1- 14- cg2316819

cg23661000 (cancer vs cancer) (cancer+normal vs

10240025 23624788 2

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- cgl078220

1-2006465 cg06791083 (cancer+normal vs (cancer+normal vs

76445988 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 14- cgl312142

cg09506001 (cancer+normal vs

36559506 (cancer+normal vs 76446161 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 14- cgl953083

cg26912671 (cancer+normal vs (cancer+normal vs

66458803 76461805 1

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 15- cgl 193545

1-9448660 cgl2658495 (cancer vs cancer)

(cancer+normal vs 49563246 9

cancer+normal)

10- (cancer vs cancer) 15- cg2065164 (cancer vs cancer) cg01467532

115738883 (cancer vs cancer) 50170642 4 (cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer+normal vs 15- cg2120458

cg05760937

134552168 (cancer+normal vs cancer+normal) 50316779 8

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

10-405225 15- cgl394197

cg20595750 (cancer vs cancer) (cancer+normal vs

65143918 8

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10-405362 15- cgl8074403 cg0069158

(cancer+normal vs (cancer+normal vs

86160762 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

10-661009 16- cg0255030

cgl9926144 (cancer+normal vs

(cancer+normal vs 69310261 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) 17- cg0699799

cg23871994

113577434 (cancer+normal vs 19287677 7 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

11- (cancer vs cancer) cg2165314

cg07737063 17-4108148

1486341 (cancer+normal vs

(cancer+normal vs 9

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

12- cg0619528

cg01589353 (cancer+normal vs 17-6658706

125500634 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer)

(cancer vs cancer) cg0341915

cg23617848 17-6658728

131452297 (cancer+normal vs

(cancer+normal vs 1

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) 17- cg24211304 cg0511586

4596426 (cancer vs cancer)

(cancer+normal vs 79439144 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

12-656703 cg03539204 cgl590565

17-8584536 (cancer+normal vs (cancer+normal vs 6

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

13- (cancer vs cancer)

19- cg2764827

cg26951340 (cancer vs cancer)

111893537 (cancer+normal vs

10928172 0

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer)

(cancer vs cancer) 19- cgl854436

cg06206670

113436564 (cancer+normal vs

(cancer+normal vs 10928178 5

cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer)

(cancer vs cancer)

cgl4737571 19- cg2304754

113436568 (cancer+normal vs

(cancer+normal vs 10928211 4

cancer+normal) cancer+normal)

13- (cancer vs cancer)

(cancer+normal vs 19- cg0266044

cg00084432

36944471 (cancer+normal vs cancer+normal) 10928233 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- (cancer vs cancer)

cg03010009 19- cg0675419

80585265 (cancer+normal vs

(cancer+normal vs 10928322 7

cancer+normal) cancer+normal)

14- cg03403507 (cancer vs cancer) 19- cg0290706 (cancer vs cancer) 32798387 (cancer vs cancer) 10928327 4 (cancer+normal vs

(cancer+normal vs cancer+normal) cancer+normal)

14- (cancer+normal vs 19- cg2306879

cgl6683572 (cancer vs cancer)

32798409 cancer+normal) 10928549 7

(cancer vs cancer)

(cancer vs cancer)

14- (cancer vs cancer) 19- cg0321604

cg24812523 (cancer+normal vs

32798762 (cancer+normal vs 10928639 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

14- (cancer vs cancer) 19- cgl396561

cg24158307 (cancer+normal vs

95599667 (cancer+normal vs 10928696 2

cancer+normal) cancer+normal)

(cancer vs cancer)

16- 2- cgl599372

_C g03494430 (cancer+normal vs (cancer vs cancer)

2177269 110064019 3

cancer+normal)

(normal vs normal)

(cancer vs cancer)

16- 2- cgO 162422

cg00900231 (cancer vs cancer) (cancer vs cancer)

50897271 153252785 9

(cancer+normal vs

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16- cgl406776

cg03346415 (cancer+normal vs 2-23840739 (cancer+normal vs

69854895 1

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

16- cg0233877

cg02619656 (cancer vs cancer) 2-23840763 (cancer+normal vs

72460083 8

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

16- 2- cgl735671

cg05347108 (cancer vs cancer) (cancer+normal vs

72460114 240230587 8

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer+normal vs 2- cg2029866

cg00898447 (cancer+normal vs

75300795 cancer+normal) 240230663 8

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

16- (cancer vs cancer) 2- cg0517119

cg00319595 (cancer+normal vs

75300861 (cancer+normal vs 240230850 7

cancer+normal) cancer+normal)

(normal vs normal)

(normal vs normal)

16- 2- cgl944956 (cancer vs cancer) cg07585257 (cancer+normal vs

85618206 240230892 5 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

16- (cancer vs cancer) 21- cg2163992

cg03551062 (cancer+normal vs

88041289 (cancer+normal vs 44089014 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16- 21- cg2716095

cg02207944 (cancer+normal vs (cancer+normal vs

89603606 44089142 2

cancer+normal) cancer+normal)

(normal vs normal) (normal vs normal)

16- (cancer vs cancer) 3- cg2373326 (cancer vs cancer) cg01279418

89623374 (cancer+normal vs 107381326 0 (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- (cancer vs cancer) 3- cg0017109

cgl3691567 (cancer+normal vs

1308616 (cancer+normal vs 124531371 2

cancer+normal) cancer+normal)

17- cg00145352 (normal vs normal) 3-12980202 cgl608109 (cancer vs cancer) 2319906 (cancer vs cancer) 6 (cancer+normal vs

(cancer vs cancer) cancer+normal) (cancer+normal vs

cancer+normal)

(normal vs normal)

17- (cancer vs cancer) cg0156281

cgl8232597 3-13420826 (cancer vs cancer)

29624396 (cancer+normal vs 3

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) cgl831341

cg00711291 3-13420961 (cancer+normal vs

71345538 (cancer+normal vs 6

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer+normal vs cg0210521

cglO 140240 3-4625188 (cancer+normal vs

76220672 cancer+normal) 1

cancer+normal)

(cancer vs cancer)

17- cgl750890

cgl9272238 (cancer+normal vs 4-38121914 (cancer vs cancer)

76220898 5

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) cg2001663

cg07366188 4-38871320 (cancer+normal vs

76220929 (cancer+normal vs 1

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) cg0581367

cgl0070788 4-53862521 (cancer+normal vs

76220955 (cancer+normal vs 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) cgl 198497

cgl2130672 4-54765826 (cancer+normal vs 9151012 (cancer+normal vs 1

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

18- cg2370681

cg22291942 (cancer vs cancer) 4-89152212 (cancer+normal vs

32398181 9

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

18- 5- cgl410462

cg03722909 (cancer vs cancer) (cancer vs cancer)

42324965 156988400 6

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

18- 5- cg2611287

cg07015525 (cancer vs cancer) (cancer+normal vs

42325086 171320720 1

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) 5- cgl634511

18-686346 cg01037496 (cancer vs cancer)

(cancer+normal vs 172306112 4

cancer+normal)

(cancer vs cancer)

19- cg2199534

cg27172769 (cancer+normal vs 5-53814891 (cancer vs cancer)

1255283 7

cancer+normal)

(cancer vs cancer) (normal vs normal)

19- (cancer vs cancer) 6- cg0806159 (cancer vs cancer) cg24300446

1255516 (cancer+normal vs 112081538 8 (cancer+normal vs cancer+normal) cancer+normal)

19- (cancer+normal vs 6- cg0719836

cg06454084 (cancer vs cancer)

47158242 cancer+normal) 145527462 9

(cancer vs cancer)

19- cgl325385

cgl5080870 (cancer vs cancer) 6-1702693 (cancer vs cancer)

47770746 6

(cancer+normal vs cancer+normal)

(normal vs normal) (cancer vs cancer)

2- cgl701759

cg03303633 (cancer+normal vs 6-28557765 (cancer+normal vs

145196972 1

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

2- cg0133031

cgl3218739 (cancer+normal vs 6-45914282 (cancer+normal vs

182850683 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- (cancer vs cancer) 7- cg0691776

cg22764497 (cancer+normal vs

236716219 (cancer+normal vs 130033247 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- (cancer vs cancer) 7- cgl448146

cg06694561 (cancer+normal vs

236716285 (cancer+normal vs 151297347 9

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cg0394738

cg06747919 7-17691191 (cancer vs cancer)

236716372 (cancer+normal vs 4

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) 8- cgl 960943

cg00746446 (cancer vs cancer)

23879137 (cancer+normal vs 100770219 8

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

2- 8- cg2554559

cg06257052 (cancer vs cancer) (cancer+normal vs

240117222 107937633 8

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cg2308942

cg20853370 8-19034837 (cancer vs cancer)

240117640 (cancer+normal vs 5

cancer+normal)

(normal vs normal) (cancer vs cancer)

2- cg0204379

cg05139187 (cancer+normal vs 8-38322629 (cancer+normal vs

24443636 1

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- (cancer vs cancer) cg0604390

cg00073794 8-49467831 (cancer+normal vs

30041338 (cancer+normal vs 8

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer) cgl 106445

2-3292757 cg03025986 (cancer vs cancer) 8-74363469 (cancer+normal vs

4

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer) 9- cg0515445

2-3480658 cg05777919 (cancer+normal vs

(cancer+normal vs 113100053 4

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- (cancer vs cancer) 9- cgl430831

cg04768463 (cancer+normal vs

55174473 (cancer+normal vs 114812406 1

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

22- cgl429911

cgl2894883 (cancer vs cancer) 9-85020050 (cancer+normal vs

22288473 5

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

22- (cancer vs cancer) (cancer+normal vs

cg00489795

24041104 (cancer+normal vs cancer+normal)

cancer+normal) (cancer vs cancer)

22- (cancer vs cancer)

cg26799416 Status - Hyper

42611379 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (cancer vs cancer) 1- cg2763667

cgl2678686 (cancer+normal vs

127327369 (cancer+normal vs 165322606 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (cancer vs cancer) 1- cgl031553

cgl9272592 (cancer+normal vs

129408521 (cancer+normal vs 165322784 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (cancer vs cancer) 1- cg2652259

cg03320743 (cancer+normal vs

147657586 (cancer+normal vs 165323232 2

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (cancer vs cancer) 1- cg2430461

cg20224111 (cancer+normal vs

195616361 (cancer+normal vs 169079632 7

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

4- 1- cgl668222

cg01578875 (cancer vs cancer) (cancer+normal vs

146804010 214435182 5

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

4- 10- cgl 158980 (cancer+normal vs cgl0569820 (cancer vs cancer)

24982540 130832268 0 cancer+normal)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) 10- cg0888117 (cancer+normal vs cg06612355

102834858 (cancer+normal vs 130832393 5 cancer+normal) cancer+normal)

(cancer vs cancer)

5- 10- cgl894703 (cancer+normal vs cgl0519882 (cancer+normal vs

179494929 70748274 2 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

5- cg0116955 (cancer+normal vs cg09645993 (cancer vs cancer) 10-831247

77289836 9 cancer+normal)

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

6- 11- cg2745728

cg24574819 (cancer vs cancer) (cancer+normal vs

102224868 35439994 4

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 11- cg2418332

cgl2616114 (cancer+normal vs

143130570 cancer+normal) 35440062 4

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 11- cg0244362 (cancer+normal vs cgl7596249

157493773 (cancer+normal vs 44335060 6 cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 11- cgl993594 (cancer+normal vs cgl4549524

24140822 (cancer+normal vs 44338782 5 cancer+normal) cancer+normal)

(cancer vs cancer)

6- 12- cg2700251 (cancer+normal vs cg08908855 (cancer vs cancer)

24140899 111835267 6 cancer+normal)

(cancer+normal vs cancer+normal)

(normal vs normal) (normal vs normal)

7- 12- cgl 158644

cgl7713751 (cancer+normal vs (cancer+normal vs

101723568 123383399 8

cancer+normal) cancer+normal)

(normal vs normal)

7- 12- cg0056028 (cancer+normal vs cgl4203426 (cancer+normal vs

101723947 49783222 4 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

7- 12- cg0351048 (cancer+normal vs cg06010390 (cancer vs cancer)

101849120 53264540 6 cancer+normal)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

7- (cancer vs cancer) 12- cg0077240 (cancer+normal vs cg01234984

101849473 (cancer+normal vs 89744471 7 cancer+normal) cancer+normal)

(cancer vs cancer)

7- (cancer vs cancer) 12- cg0181419 (cancer+normal vs cgl 1895696

105283982 (cancer+normal vs 89744524 1 cancer+normal) cancer+normal)

(cancer vs cancer)

7- 12- cgl774082 (cancer+normal vs cgl7102674 (cancer+normal vs

140034703 89744609 2 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer) 13- cg2601516

7-2148642 cgl6329842 (cancer+normal vs

(cancer+normal vs 37838311 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer) 13- cg0229783

7-4747216 cg01275887 (cancer+normal vs

(cancer+normal vs 92002454 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer+normal vs 14- cgl851587

7-6465799 cgl8642425 (cancer+normal vs cancer+normal) 72943461 2

cancer+normal)

(normal vs normal)

8- 15- cg2373706 (cancer+normal vs cg24525461 (cancer+normal vs

131011240 63894296 2 cancer+normal) cancer+normal)

(cancer vs cancer)

8- 15- cg2492457 (cancer+normal vs cg00470636 (cancer+normal vs

26440349 90735148 7 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- (cancer vs cancer) 15- cgl982313

cg02712949 (cancer+normal vs

87570714 (cancer+normal vs 99559002 8

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

15- cg0809629

8-9260354 cgl0359460 (cancer vs cancer) (cancer+normal vs

99791282 1

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) cg0066460 (cancer+normal vs

8-9537322 cgl0419849 16-2198075

(cancer+normal vs 9 cancer+normal) cancer+normal)

(cancer vs cancer)

9- (cancer+normal vs 16- cg0730132

cgl4467276 (cancer+normal vs

96846674 cancer+normal) 85648263 9

cancer+normal)

(normal vs normal)

(cancer vs cancer)

9- 16- cg0393613 (cancer+normal vs cgl4155501 (cancer vs cancer)

99264127 86371248 5 cancer+normal)

(cancer+normal vs

cancer+normal) (cancer vs cancer)

16- cgl470507

(normal vs normal) (cancer+normal vs

88292996 9

cancer+normal)

(normal vs normal)

16- cgl033088

Status - Hyper (cancer+normal vs

88729968 5

cancer+normal)

(normal vs normal) (normal vs normal)

1- cg2528808

cg04308687 (cancer+normal vs 17-6347142 (cancer+normal vs

100231682 5

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (normal vs normal) 17- cg0697602

cgl7935811 (cancer+normal vs

12678641 (cancer+normal vs 77810742 5

cancer+normal) cancer+normal)

(cancer vs cancer)

1- (normal vs normal) 17- cgl971577 (cancer+normal vs cg01346152

12678761 (cancer+normal vs 77810912 1 cancer+normal) cancer+normal)

(normal vs normal)

1- 18- cg0793355 (cancer+normal vs cg03317045 (cancer+normal vs

175161069 45934595 2 cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

1- 19- cgl033883

cg22705746 (cancer+normal vs (cancer+normal vs

203320506 48833410 0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (normal vs normal) 19- cgl731521

cgl0985914 (cancer+normal vs

212769641 (cancer+normal vs 48833559 9

cancer+normal) cancer+normal)

(normal vs normal)

1- cgl271358 (cancer+normal vs cgl 1526198 (cancer+normal vs 19-940724

23854847 3 cancer+normal) cancer+normal)

(cancer vs cancer)

1- 2- cg2443018

cgl8232347 (normal vs normal) (cancer+normal vs

31655009 128173685 9

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (normal vs normal) 2- cg0247360

cgl5687600 (cancer+normal vs

59280952 (cancer+normal vs 128173750 0

cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

1- (normal vs normal) 2- cg2469595

cg03611060 (cancer+normal vs

59281067 (cancer+normal vs 162364264 0

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

1- 2- cgl010743

cgl3938909 (cancer+normal vs (cancer+normal vs

89873226 177021899 4

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

10- 2- cg2570832

cgl6485048 (cancer+normal vs (cancer+normal vs

13749193 177022056 8

cancer+normal) cancer+normal)

(cancer vs cancer)

10- 2- cgl833877

cgl4014799 (normal vs normal) (cancer+normal vs

22606053 177022121 5

cancer+normal)

(normal vs normal) (cancer vs cancer)

10- 2- cg0566941

cg02076355 (cancer+normal vs (cancer+normal vs

45474372 177022962 8

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 2- cg0978493

cg06230206 (normal vs normal) (cancer+normal vs

126456119 177023062 4

cancer+normal)

11- 2- cgl512756 (cancer+normal vs cg06666008 (normal vs normal)

31819464 231729487 3 cancer+normal)

11- cgl489357 (cancer+normal vs cgl6865446 (normal vs normal) 2-23604202

31822302 6 cancer+normal)

11- cg23287710 (normal vs normal) 2- cgl579641 (cancer+normal vs 31822526 241923082 7 cancer+normal)

(cancer vs cancer)

11- cg0602379

cg09224689 (normal vs normal) 20-3653555 (cancer+normal vs

31825166 1

cancer+normal)

(normal vs normal)

11- 21- cg2464112

cg04938549 (normal vs normal) (cancer+normal vs

31825214 40721130 5

cancer+normal)

11- 3- cg0184504 (cancer+normal vs cg09217215 (normal vs normal)

31829582 118753005 1 cancer+normal)

(cancer vs cancer)

11- 3- cg0345817

cgl l l62118 (normal vs normal) (cancer+normal vs

31837104 157815672 2

cancer+normal)

(cancer vs cancer)

11- 3- cg0540176

cg06312283 (normal vs normal) (cancer+normal vs

31840628 157815808 4

cancer+normal)

(cancer vs cancer)

11- 3- cg0909522 (normal vs normal) cg20512711 (normal vs normal)

31841524 157816094 2 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

11- 3- cg0008948

cg24701575 (normal vs normal) (cancer+normal vs

31845389 157816330 6

cancer+normal)

11- cg0038086 (cancer+normal vs cg08370146 (normal vs normal) 3-28616404

31849262 0 cancer+normal)

12- 4- cgl747316 (cancer+normal vs cgl 1026555 (normal vs normal)

124247223 105411756 5 cancer+normal)

12- 4- cg2274750 (cancer+normal vs cg23588713 (normal vs normal)

56523270 175635801 7 cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

12- 4- cg0439208

cg01063813 (normal vs normal) (cancer+normal vs

57504948 186732926 2

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

12- 4- cg0279030

cg27320213 (normal vs normal) (cancer+normal vs

57504988 186732932 5

cancer+normal)

(normal vs normal) (cancer vs cancer)

12- 4- cg2678534

cg25671716 (cancer+normal vs (cancer+normal vs

96441714 186732936 6

cancer+normal) cancer+normal)

(cancer vs cancer)

13- 4- cgl392144

cgl6033633 (normal vs normal) (cancer+normal vs

100624855 186733024 4

cancer+normal)

(normal vs normal)

13- cgl683872

cgO 1792403 (normal vs normal) 4-43901032 (cancer+normal vs

100626995 9

cancer+normal)

(cancer vs cancer)

13- 5- cg0136005

cg25845367 (normal vs normal) (cancer+normal vs

100627175 122434944 4

cancer+normal)

13- 5- cg2704783 (cancer+normal vs cg25527494 (normal vs normal)

100641243 158533081 6 cancer+normal)

13- 5- cg0953314 (cancer+normal vs cgl9385331 (normal vs normal)

100641867 178563145 5 cancer+normal)

13- 5- cg2322105 (cancer+normal vs cg05072470 (normal vs normal)

100643858 179740743 2 cancer+normal)

(normal vs normal)

13- 5- cgl 133084

_C gl0445449 (normal vs normal) (cancer+normal vs

100644420 180700651 3

cancer+normal)

13- cgl620442 (cancer+normal vs cg03786327 (normal vs normal) 5-44332757

100644473 0 cancer+normal)

13- cg2662108 (cancer+normal vs cgl 1694262 (normal vs normal) 5-74965039

100644657 8 cancer+normal) 13- 6- cg2584311

cgl6762841 (normal vs normal) (cancer+normal vs

100646453 134217613 5 cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- 6- cgl 1997708 cgl 131404

(normal vs normal) (cancer+normal vs 114927854 143380966 2 cancer+normal)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer)

(normal vs normal) cgl839805

cg03268893

27557503 6-1607922 (cancer+normal vs

(cancer+normal vs 6

cancer+normal) cancer+normal)

14- (cancer vs cancer)

6- cgl758625

cg23920953 (normal vs normal)

70038505 (cancer+normal vs

170598215 6

cancer+normal)

14- cgl653767

cgl8477204 (normal vs normal) (cancer+normal vs

70038884 6-30851624

6 cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

14- (normal vs normal) cg2521245

cg02380334 (normal vs normal)

70038925 6-31461853 (cancer+normal vs

7

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer)

(normal vs normal)

cgl4539393 cg0133720

70038949 6-32063835 (cancer+normal vs

(cancer+normal vs 7

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

(normal vs normal)

16-745663 cg2626642

cg02958327 6-32063838 (cancer+normal vs

(cancer+normal vs 7

cancer+normal) cancer+normal)

(cancer vs cancer)

16-745685 cg0752491

cg01003448 (normal vs normal) 6-32063901 (cancer+normal vs

9

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

(normal vs normal)

16-745687 cg0087298

cg07482202 6-32063991 (cancer+normal vs

(cancer+normal vs 4

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) cg0148511

cg04313875 (normal vs normal)

1553202 6-32064677 (cancer+normal vs

7

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

17- (cancer vs cancer) cg2708134

cg03026373

36715787 (cancer+normal vs 6-32064692 (cancer+normal vs

6

cancer+normal) cancer+normal)

17- (cancer vs cancer) cgl579332

cgl4862207 (normal vs normal)

36715798 6-32064749 (cancer+normal vs

9

cancer+normal)

17- cg04194674 cgl810233

(normal vs normal) (cancer+normal vs

36715953 6-32064810

7 cancer+normal)

17- cgl651695

cgOl 122302 (normal vs normal) (cancer+normal vs

42392668 6-32765109

9 cancer+normal)

17- (cancer vs cancer)

cgl 1088422 cg0174549

6-34206084 (cancer+normal vs

42392697 (normal vs normal) 9 cancer+normal)

(normal vs normal)

17- (cancer vs cancer) cg0347435

cgl0712561

42392983 (cancer+normal vs 6-45387347 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) cg2635828

cg00023001 (normal vs normal)

55938748 6-45387395 (cancer+normal vs

6

(cancer+normal vs cancer+normal) cancer+normal) (cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

17- 7- cg2610098

cg22451358 (normal vs normal) (cancer+normal vs

55938871 100202882 6

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- (normal vs normal) 7- cg2568048

cg06615719 (cancer+normal vs

1455513 (cancer+normal vs 100203114 6

cancer+normal) cancer+normal)

19- 7- cg2103514 (cancer+normal vs cg03306486 (normal vs normal)

1467952 151136940 2 cancer+normal)

(normal vs normal)

19- cg2475516

cgl9333963 (normal vs normal) 7-26416987 (cancer+normal vs

1467979 3

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (normal vs normal)

19- cg0856856

cgl0565187 (normal vs normal) 7-42834498 (cancer+normal vs

1468943 1

(cancer+normal vs cancer+normal) cancer+normal)

19- cg2466960 (cancer+normal vs cg08958549 (normal vs normal) 7-77426814

1469891 2 cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

19- 8- cg0545805

cg25814383 (normal vs normal) (cancer+normal vs

19336240 102503892 2

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- (normal vs normal) 8- cg2034218

cgl0369688 (cancer+normal vs

39898283 (cancer+normal vs 102503970 4

cancer+normal) cancer+normal)

(normal vs normal)

19- cgl274324 (cancer+normal vs cg03096975 (cancer+normal vs 8-49636840

46142574 8 cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

19- cg2452394

cg07804711 (cancer+normal vs 8-72916620 (cancer+normal vs

46142647 8

cancer+normal) cancer+normal)

2- cg23539753 (normal vs normal) Status - Hypo

231280698

(normal vs normal)

2- 1- cgl725345 (cancer+normal vs cg09456094 (cancer+normal vs

231280878 114522670 9 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- (normal vs normal) 1- cg0826480

cgl 1702456 (cancer+normal vs

231280907 (cancer+normal vs 155291224 5

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

2- cg0823171

cg05091653 (cancer+normal vs 1-1566687 (cancer+normal vs

231281474 0

cancer+normal) cancer+normal)

(cancer vs cancer)

2- 1- cgl049343

cg08299783 (normal vs normal) (cancer+normal vs

48920986 161168957 6

cancer+normal)

20- cgl611045 (cancer+normal vs cg22610655 (normal vs normal) 1-16344977

20346426 5 cancer+normal)

(cancer vs cancer)

20- 1- cg0992248

cg08183724 (normal vs normal) (cancer+normal vs 21497429 168698463 1

cancer+normal)

(normal vs normal) (cancer vs cancer)

20- 1- cg2126684

cg07668993 (cancer+normal vs (cancer+normal vs

43883307 168698479 5

cancer+normal) cancer+normal)

22- (normal vs normal) 1- cg0263372 (cancer vs cancer) cg07713361

36649144 (cancer+normal vs 172113506 9 (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(normal vs normal)

3- 1- cg2521496 (cancer vs cancer) cgl3519902 (cancer+normal vs

50639079 172113756 6 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

3- 1- cg2400214

cg08994384 (normal vs normal) (cancer+normal vs

62363642 172113920 9

cancer+normal)

(normal vs normal) (cancer vs cancer)

4- 1- cg2145088

cg07174665 (cancer+normal vs (cancer+normal vs

129474594 172114047 8

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

4- 1- cgl717822

cgl7521583 (cancer+normal vs (cancer+normal vs

129474618 172114068 0

cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

1- cg0332205

4-809452 cg24464265 (cancer+normal vs (cancer+normal vs

172114419 7

cancer+normal) cancer+normal)

5- 1- cg2279636 (cancer+normal vs cg21233688 (normal vs normal)

134880353 214477063 3 cancer+normal)

(normal vs normal)

5- cg2616105 (cancer+normal vs cg01065586 (cancer+normal vs 1-27881600

52404911 7 cancer+normal) cancer+normal)

6- 10- cgl520544 (cancer+normal vs cgl9095187 (normal vs normal)

108437051 126782357 1 cancer+normal)

6- 10- cgl l l l627 (cancer+normal vs cg06103642 (normal vs normal)

108496716 134334283 4 cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- 10- cg2695346 (cancer+normal vs cg08501292 (normal vs normal)

25962987 31872296 9 cancer+normal)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

6- (normal vs normal) 10- cgl089451

cg06153893 (cancer+normal vs

25963109 (cancer+normal vs 90712478 2

cancer+normal) cancer+normal)

(cancer vs cancer)

6- (normal vs normal) 10- cg0999048 (cancer+normal vs cg21844956

25963442 (cancer+normal vs 90712684 1 cancer+normal) cancer+normal)

6- 10- cg0721652 (cancer+normal vs cg08384314 (normal vs normal)

30711680 90712739 9 cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

6- cg0351209

cg23514619 (normal vs normal) 11-2730129 (cancer+normal vs

43237330 8

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

6- 11- cgl373483

cg20434586 (normal vs normal) (cancer+normal vs

43237511 68779817 3

(cancer+normal vs cancer+normal) cancer+normal)

6- 11- cg2388213 (cancer+normal vs cg00482398 (normal vs normal)

43424018 68779826 1 cancer+normal)

7- 11- cgl807684 (cancer+normal vs cg04937416 (normal vs normal)

157479272 93262607 2 cancer+normal)

(cancer vs cancer)

7- cgl 183069

cg05124021 (normal vs normal) 12-2289797 (cancer+normal vs

157487066 4

cancer+normal)

8- 12- cgl973774 (cancer+normal vs cgl4156441 (normal vs normal)

126447096 96628738 6 cancer+normal)

8- cg02226645 (normal vs normal) 13- cgl093822 (cancer+normal vs 65291287 42197109 1 cancer+normal)

(cancer vs cancer)

8- 13- cgl276203

cg01517740 (normal vs normal) (cancer+normal vs

65291990 73833939 9

cancer+normal)

(cancer vs cancer)

8- 14- cgl422566

cgl 1626236 (normal vs normal) (cancer+normal vs

65292321 102394448 5

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 14- cg2316819

cg20577468 (cancer+normal vs

80803196 (normal vs normal) 23624788 2

cancer+normal)

(cancer vs cancer)

14- cgl078220

Status - Hypo (cancer+normal vs

76445988 6

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

1- 14- cgl312142

cg27508545 (cancer vs cancer) (cancer+normal vs

10240017 76446161 8

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

1- 14- cgl953083

cg23661000 (cancer vs cancer) (cancer+normal vs

10240025 76461805 1

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

15- cg2065164

1-1361077 cg00305774 (normal vs normal) (cancer+normal vs

50170642 4

cancer+normal)

(cancer vs cancer)

1- 15- cg2120458

cgl2486498 (normal vs normal) (cancer+normal vs

230975106 50316779 8

cancer+normal)

1- 15- cgl815456 (cancer+normal vs cg22950111 (normal vs normal)

243651920 51464013 7 cancer+normal)

1- 15- cg2698792 (cancer+normal vs cg01983216 (normal vs normal)

244217562 62767926 8 cancer+normal)

(cancer vs cancer)

1- 15- cgl394197

cgl5393025 (normal vs normal) (cancer+normal vs

244318867 65143918 8

cancer+normal)

(cancer vs cancer)

10- 15- cg0069158

cg26275858 (normal vs normal) (cancer+normal vs

131694689 86160762 6

cancer+normal)

10- 16- cg0627165 (cancer+normal vs cgl0084213 (normal vs normal)

134058796 23144103 2 cancer+normal)

(cancer vs cancer)

10- 16- cg0255030

cgl l l51314 (normal vs normal) (cancer+normal vs

134548998 69310261 8

cancer+normal)

10- 16- cg0635768 (cancer+normal vs cgl3793681 (normal vs normal)

3313302 70812814 5 cancer+normal)

(normal vs normal)

(cancer vs cancer)

16- cg0572073 (cancer+normal vs

10-405225 cg20595750 (cancer vs cancer)

84829007 3 cancer+normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer)

10- 17- cg0699799

cg09137125 (normal vs normal) (cancer+normal vs

7486981 19287677 7

cancer+normal)

11- 17- cg2467006 (cancer+normal vs cg08718050 (normal vs normal)

70563677 37216821 3 cancer+normal)

(cancer vs cancer)

11- cg2165314

cg26429499 (normal vs normal) 17-4108148 (cancer+normal vs

70563792 9

cancer+normal)

12- (normal vs normal) cg0619528 (cancer vs cancer) cg01589353 17-6658706

125500634 (cancer+normal vs 0 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

12- cg0341915

cg23592392 (normal vs normal) 17-6658728 (cancer+normal vs

130434412 1

cancer+normal)

(cancer vs cancer)

12- cgl590565

cgl6614527 (normal vs normal) 17-8584536 (cancer+normal vs

50400225 6

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

13- 19- cg2764827

cg26951340 (cancer vs cancer) (cancer+normal vs

111893537 10928172 0

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

13- 19- cgl854436

cgl 1030811 (normal vs normal) (cancer+normal vs

25743608 10928178 5

cancer+normal)

(cancer vs cancer)

13- 19- cg2304754

cgl3055385 (normal vs normal) (cancer+normal vs

25743999 10928211 4

cancer+normal)

(cancer vs cancer)

14- 19- cg0266044

cgl9961800 (normal vs normal) (cancer+normal vs

62550978 10928233 0

cancer+normal)

(cancer vs cancer)

14- 19- cg0675419

cgl8872420 (normal vs normal) (cancer+normal vs

78023429 10928322 7

cancer+normal)

(cancer vs cancer)

14- 19- cg0290706

cg03505817 (normal vs normal) (cancer+normal vs

93735925 10928327 4

cancer+normal)

(cancer vs cancer)

14- 19- cg0321604

cgl0948630 (normal vs normal) (cancer+normal vs

95562368 10928639 3

cancer+normal)

(cancer vs cancer)

14- 19- cgl396561

cg07015803 (normal vs normal) (cancer+normal vs

99655593 10928696 2

cancer+normal)

(cancer vs cancer)

14- cgl406776

cgl6452866 (normal vs normal) 2-23840739 (cancer+normal vs

99655676 1

cancer+normal)

(cancer vs cancer)

15- cg0233877

cg23047203 (normal vs normal) 2-23840763 (cancer+normal vs

79357160 8

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

16- 2- cgl735671

cg00900231 (cancer vs cancer) (cancer+normal vs

50897271 240230587 8

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

16- 2- cg2029866

cg09462089 (normal vs normal) (cancer+normal vs

58329456 240230663 8

cancer+normal)

(cancer vs cancer)

16- 2- cg0517119

cg07864976 (normal vs normal) (cancer+normal vs

72459595 240230850 7

cancer+normal)

(normal vs normal)

16- 2- cgl944956 (cancer vs cancer) cg27088725 (normal vs normal)

72459796 240230892 5 (cancer+normal vs

cancer+normal)

16- 2- cg0355473 (cancer+normal vs cg07209034 (normal vs normal)

72459825 241719655 6 cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

16- 21- cg2163992

cg02619656 (cancer vs cancer) (cancer+normal vs

72460083 44089014 2

(cancer+normal vs cancer+normal) cancer+normal) (normal vs normal)

(cancer vs cancer) (cancer vs cancer)

16- 21- cg2716095

cg05347108 (cancer vs cancer) (cancer+normal vs

72460114 44089142 2

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

16- 3- cg2373326 (cancer vs cancer) cg06250127 (normal vs normal)

84940830 107381326 0 (cancer+normal vs

cancer+normal)

(normal vs normal) (cancer vs cancer)

16- 3- cg0017109

cg07585257 (cancer+normal vs (cancer+normal vs

85618206 124531371 2

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

16- (cancer vs cancer) cgl608109

cg01279418 3-12980202 (cancer+normal vs

89623374 (cancer+normal vs 6

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- (cancer vs cancer) cgl831341

cgl3691567 3-13420961 (cancer+normal vs

1308616 (cancer+normal vs 6

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- 3- cg0284722 (cancer+normal vs cg00145352 (cancer vs cancer)

2319906 171523157 0 cancer+normal)

(cancer+normal vs

cancer+normal)

(normal vs normal)

17- (cancer vs cancer) cg2630992 (cancer+normal vs cgl8232597 3-24083947

29624396 (cancer+normal vs 9 cancer+normal) cancer+normal)

(cancer vs cancer)

17- cg0210521

cgl5536947 (normal vs normal) 3-4625188 (cancer+normal vs

65471303 1

cancer+normal)

17- 4- cg0838415 (cancer+normal vs cg26758486 (normal vs normal)

71533286 119948360 5 cancer+normal)

17- 4- cg0975785 (cancer+normal vs cgl 1348106 (normal vs normal)

75208807 119948505 9 cancer+normal)

(normal vs normal)

17- 4- cgl304291

cg05561386 (normal vs normal) (cancer+normal vs

76455102 119948542 8

cancer+normal)

(cancer vs cancer)

17- cg2001663

cg09591867 (normal vs normal) 4-38871320 (cancer+normal vs

79098558 1

cancer+normal)

(cancer vs cancer)

17- cg0581367

cgl0665961 (normal vs normal) 4-53862521 (cancer+normal vs

8958039 3

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

18- cgl 198497

cg22291942 (cancer vs cancer) 4-54765826 (cancer+normal vs

32398181 1

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

18- cg2370681

cg03722909 (cancer vs cancer) 4-89152212 (cancer+normal vs

42324965 9

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

18- 5- cg2611287

cg07015525 (cancer vs cancer) (cancer+normal vs

42325086 171320720 1

(cancer+normal vs cancer+normal) cancer+normal)

18-686346 cg01037496 (normal vs normal) 5- cgl302253 (cancer+normal vs (cancer vs cancer) 171831028 4 cancer+normal)

(cancer+normal vs

cancer+normal)

(normal vs normal)

18- 6- cg0806159 (cancer vs cancer) cg03148084 (normal vs normal)

72201665 112081538 8 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

18- cgl701759

cgl5391531 (normal vs normal) 6-28557765 (cancer+normal vs

74691423 1

cancer+normal)

(normal vs normal)

2- cg0259843 (cancer+normal vs cg03303633 (cancer+normal vs 6-43997388

145196972 0 cancer+normal) cancer+normal)

(normal vs normal) (cancer vs cancer)

2- cg0133031

cgl3218739 (cancer+normal vs 6-45914282 (cancer+normal vs

182850683 6

cancer+normal) cancer+normal)

(normal vs normal)

2- cg0059340

cg22373519 (normal vs normal) 6-52377740 (cancer+normal vs

236761021 4

cancer+normal)

2- cg0302430 (cancer+normal vs cgl6096176 (normal vs normal) 6-52440589

236826207 1 cancer+normal)

2- cg2268437 (cancer+normal vs cg06526980 (normal vs normal) 6-6737080

236826245 0 cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

2- 7- cg0691776

cg06257052 (cancer vs cancer) (cancer+normal vs

240117222 130033247 3

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

2- 7- cg0153948 (cancer+normal vs cg05139187 (cancer+normal vs

24443636 130040067 4 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

7- _C gl448146

2-3292757 cg03025986 (cancer vs cancer) (cancer+normal vs

151297347 9

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

2- 8- cg2554559

cgl7681516 (normal vs normal) (cancer+normal vs

43295389 107937633 8

cancer+normal)

(cancer vs cancer)

2- cg0204379

cgl l418389 (normal vs normal) 8-38322629 (cancer+normal vs

95978534 1

cancer+normal)

(cancer vs cancer)

20- cg0604390

cgl6718537 (normal vs normal) 8-49467831 (cancer+normal vs

43530216 8

cancer+normal)

(cancer vs cancer)

20- (normal vs normal) cgl 106445

cgl4523475 8-74363469 (cancer+normal vs

62550740 (cancer vs cancer) 4

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

22- 9- cg0515445

cgl2894883 (cancer vs cancer) (cancer+normal vs

22288473 113100053 4

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

3- 9- cgl430831

cg21767191 (normal vs normal) (cancer+normal vs

17082105 114812406 1

cancer+normal)

(cancer vs cancer)

3- cgl429911

cg23180636 (normal vs normal) 9-85020050 (cancer+normal vs

44140250 5

cancer+normal)

4- (normal vs normal)

cg01578875

146804010 (cancer vs cancer) (normal vs normal) (cancer vs cancer)

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

4- cgl0569820 (cancer vs cancer) Status - Hyper

24982540

(cancer+normal vs

cancer+normal)

(normal vs normal)

1- cgl485987 (normal vs normal)

5-2515708 cgl7870484 (normal vs normal)

154238265 4 (cancer+normal vs

cancer+normal)

5- cgl551906

cg21050001 (normal vs normal) 1-21348906 (normal vs normal)

36662804 5

(normal vs normal)

5- 1- cgl668222

cgl 1861970 (normal vs normal) (cancer+normal vs

67484008 214435182 5

cancer+normal)

(normal vs normal)

(cancer vs cancer)

5- cg2093244

cg09645993 (cancer vs cancer) 1-54359778 (normal vs normal)

77289836 0

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

6- cg0847768

cg24574819 (cancer vs cancer) 1-566570 (normal vs normal)

102224868 7

(cancer+normal vs

cancer+normal)

6- cgl589278

cg07259165 (normal vs normal) 1-6309343 (normal vs normal)

113639635 5

6- 10- cg2613794

cg05966641 (normal vs normal) (normal vs normal)

134637428 131761302 0

6- 10- cg2605683

cg24145613 (normal vs normal) (normal vs normal)

163558575 21814538 1

6- 10- cg2608269

cgl 1724750 (normal vs normal) (normal vs normal)

163558823 70748261 0

6- 10- cg0323618

cg09233791 (normal vs normal) (normal vs normal)

166908811 89621862 4

6- 10- cg0498328

cgl9076258 (normal vs normal) (normal vs normal)

17032431 98156179 9

6- 11- cg0391006

cgl0807105 (normal vs normal) (normal vs normal)

17032522 115372874 5

6- l icg0857251

cg25017994 (normal vs normal)

29627296 nes (normal vs normal)

10409 3

6- cgl958684

cgl9628686 (normal vs normal) 11-2211939 (normal vs normal)

33158503 5

(normal vs normal)

7- 11- cg0362701

cgl7713751 (cancer+normal vs (normal vs normal)

101723568 63382085 5

cancer+normal)

(normal vs normal)

7- 11- cg0720914

cgl4203426 (cancer+normal vs (normal vs normal)

101723947 68171070 1

cancer+normal)

(normal vs normal)

(cancer vs cancer)

7- 12- cg0236873

cg06010390 (cancer vs cancer) (normal vs normal)

101849120 27273951 7

(cancer+normal vs

cancer+normal)

7- 12- cg2515576

cgl5264162 (normal vs normal) (normal vs normal)

154035993 34317569 6

(normal vs normal)

7- 12- cg2423286

cgl9130610 (normal vs normal) (cancer+normal vs

156190025 48478849 9

cancer+normal) 7- 12- cg0685818

cgl0784273 (normal vs normal) (normal vs normal)

157281251 54144921 6

7- 12- cg0557384

cgl4289852 (normal vs normal) (normal vs normal)

157394633 54354590 4

12- cgl207153

7-1650459 cg03489907 (normal vs normal) (normal vs normal)

54393971 6

(normal vs normal)

(cancer vs cancer) 12- cgl764709

7-2148642 cgl6329842 (normal vs normal)

(cancer+normal vs 54474036 1

cancer+normal)

cg2716670

7-6198703 cg21828663 (normal vs normal) 12-9227209 (normal vs normal)

7

(normal vs normal)

8- 13- cgl 159796

cg24525461 (cancer+normal vs (normal vs normal)

131011240 19299584 9

cancer+normal)

(normal vs normal)

(cancer vs cancer)

13- cg0967793

8-9260354 cgl0359460 (cancer vs cancer) (normal vs normal)

23423308 8

(cancer+normal vs

cancer+normal)

13- cg0917948

8-9952926 cg02192555 (normal vs normal) (normal vs normal)

39612920 5

13- cg0047605

8-9953022 cgl 1824826 (normal vs normal) (normal vs normal)

50705383 4

9- 13- cg2110694

cgl7792192 (normal vs normal) (normal vs normal)

138774526 65533500 6

(normal vs normal)

(cancer vs cancer)

9- 14- cg0689214

cgl4155501 (cancer vs cancer) (normal vs normal)

99264127 106113192 1

(cancer+normal vs

cancer+normal)

GECaG (cancer vs 14- cg2364196

(normal vs normal) cancer) 62523700 4

14- cgl544861

Status - Hyper (normal vs normal)

72399846 6

1- 14- cg0299635

cg09008705 (cancer vs cancer) (normal vs normal)

115880865 81879375 5

1- 15- cg2687507

cg00662647 (cancer vs cancer) (normal vs normal)

234350051 25200490 3

1- 15- cgl266044

cg26150071 (cancer vs cancer) (normal vs normal)

34629559 66795737 5

(normal vs normal)

1- 15- cg0809629

cg05046525 (cancer vs cancer) (cancer+normal vs

35395821 99791282 1

cancer+normal)

1- 16- cg0677360

cgl 1666087 (cancer vs cancer) (normal vs normal)

49242513 18995157 4

1- 16- cg0399129

cgl6573178 (cancer vs cancer) (normal vs normal)

49242519 30429837 7

10- 16- cg0022152

cg03701427 (cancer vs cancer) (normal vs normal)

82117089 31085579 5

10- 16- _C g0694447

cg01229798 (cancer vs cancer) (normal vs normal)

88126853 32857007 2

11- 16- cg2646937

cg26578621 (cancer vs cancer) (normal vs normal)

110583377 33935427 9

11- cg0389669

cg06072021 (cancer vs cancer) 16-3493440 (normal vs normal)

128564106 4

11- 16- cg0749491

cgl7872757 (cancer vs cancer) (normal vs normal)

128564180 46461571 4

(normal vs normal)

11- 16- cgl033088

cg03323292 (cancer vs cancer) (cancer+normal vs

134146132 88729968 5

cancer+normal) 11- 17- cg0304924

cgl 1855526 (cancer vs cancer) (normal vs normal)

30607068 16593601 9

(normal vs normal)

11- cg2528808

cg26121782 (cancer vs cancer) 17-6347142 (cancer+normal vs

8284312 5

cancer+normal)

11- 18- cg2132033

cgl2740527 (cancer vs cancer) (normal vs normal)

8289974 40695592 4

12- 19- cg0858777

cg09736112 (cancer vs cancer) (normal vs normal)

15475690 30363203 5

12- cg0716581

cg08972130 (cancer vs cancer) 19-3360732 (normal vs normal)

24715478 1

12- 19- cgl560770

cg06797925 (cancer vs cancer) (normal vs normal)

8548978 54041308 8

13- (cancer vs cancer) 2- cg0358126

cg25264081 (normal vs normal)

95620306 (cancer vs cancer) 106192732 2

14- 2- cgl 100398

cgl5698066 (cancer vs cancer) (normal vs normal)

100438647 132182417 4

(normal vs normal)

14- 2- cg2469595

cg21164440 (cancer vs cancer) (cancer+normal vs

100438737 162364264 0

cancer+normal)

14- 2- cg0881473

cg05218346 (cancer vs cancer) (normal vs normal)

70041283 177065985 6

15- 2- cg2215725

cg09155997 (cancer vs cancer) (normal vs normal)

28351619 190788356 5

15- cgl200099

cg04803843 (cancer vs cancer) 2-27665139 (normal vs normal)

28351906 5

15- cg0766926

cg03061682 (cancer vs cancer) 2-88316847 (normal vs normal)

28352098 0

15- 20- cg0267253

cg25968835 (cancer vs cancer) (normal vs normal)

93631754 34680964 0

16- 20- cg0467768

cgl6368442 (cancer vs cancer) (normal vs normal)

10276799 57426743 3

16- 20- cgl516044

cg09746736 (cancer vs cancer) (normal vs normal)

55690130 57426749 5

19- 20- cg0710559

cgl5409931 (cancer vs cancer) (normal vs normal)

34973341 57427472 6

(normal vs normal)

19- 21- cg2464112

cg04497176 (cancer vs cancer) (cancer+normal vs

34973644 40721130 5

cancer+normal)

(normal vs normal)

2- (cancer vs cancer) 22- cg0125354

cg09667303 (cancer+normal vs

144695257 (cancer vs cancer) 31556314 5

cancer+normal)

2- 22- cg2732175

cg20593611 (cancer vs cancer) (normal vs normal)

164593221 45148218 0

2- 22- cg0651694

cg08808128 (cancer vs cancer) (normal vs normal)

29338432 45148223 7

(cancer vs cancer)

2- (cancer vs cancer) 3- cg2250577

cg21972382 (normal vs normal)

29339076 (cancer+normal vs 113822317 8

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) 3- cg0065801

cg05038216 (normal vs normal)

29339091 (cancer+normal vs 178865678 6

cancer+normal)

2- cg2757206

cg25840208 (cancer vs cancer) 3-25728371 (normal vs normal)

31457043 8

2- cg0667867

cg08130988 (cancer vs cancer) 3-55523099 (normal vs normal)

56150925 8

2- 4- cg0178984

cgl0089527 (cancer vs cancer) (normal vs normal)

66653254 135865584 6

2- cg24171907 (cancer vs cancer) 4- cg2359624 (normal vs normal) 68546579 165109834 9

4- cg2413258

2-7058390 cg05648183 (cancer vs cancer) (normal vs normal)

165118938 0

4- cgl940354

2-7058432 cg04174211 (cancer vs cancer) (normal vs normal)

174438312 1

(normal vs normal)

20- (cancer vs cancer) cgl683872

cg09279949 4-43901032 (cancer+normal vs

23030250 (cancer vs cancer) 9

cancer+normal)

20- cg2676715

cg25932164 (cancer vs cancer) 4-77069770 (normal vs normal)

37434950 4

(cancer vs cancer)

20- (cancer vs cancer) 5- cg2331110 (normal vs normal) cg20265733

61051032 (normal vs normal) 115387951 8 (cancer+normal vs

cancer+normal)

20- (cancer vs cancer) 5- cg2708795

cgl4980983 (normal vs normal) 61051039 (normal vs normal) 122430153 6

21- 5- cgl294914

cg02485200 (cancer vs cancer) (normal vs normal)

27011788 134259545 1

21- 5- cgl016516

cg24262066 (cancer vs cancer) (normal vs normal)

28217060 168728586 7

21- 5- cg0979963

cg00472814 (cancer vs cancer) (normal vs normal)

28217676 172199460 3

(normal vs normal)

3- 5- cgl 133084

cg03424342 (cancer vs cancer) (cancer+normal vs

120169783 180700651 3

cancer+normal)

3- 6- cgl387648

cgl5109851 (cancer vs cancer) (normal vs normal)

120169821 147124881 1

3- 6- cg0040745

cg20506715 (cancer vs cancer) (normal vs normal)

128720433 168227261 7

cg2610572

3-238392 cg01295518 (cancer vs cancer) 6-27511112 (normal vs normal)

5

(normal vs normal)

3- cg2521245

cg25805709 (cancer vs cancer) 6-31461853 (cancer+normal vs

44596770 7

cancer+normal)

4- cg0968438

cg05118638 (cancer vs cancer) 6-31697988 (normal vs normal)

126237371 1

4- cg2331407

cgl0731073 (cancer vs cancer) 6-32765117 (normal vs normal)

126237373 1

4- cg0840558

cgl8120376 (cancer vs cancer) 6-33043138 (normal vs normal)

142054254 7

4- cgl873595

cg06340552 (cancer vs cancer) 6-34113908 (normal vs normal)

142054329 6

4- cg2264631

cg20599022 (cancer vs cancer) 7-1409216 (normal vs normal)

142054446 1

(normal vs normal)

4- cg2475516

cg04478179 (cancer vs cancer) 7-26416987 (cancer+normal vs

154680909 3

cancer+normal)

(normal vs normal)

4- cg0856856

cg27272220 (cancer vs cancer) 7-42834498 (cancer+normal vs

156680400 1

cancer+normal)

4- cgl728258

cg22664296 (cancer vs cancer) 7-63924407 (normal vs normal)

156680518 4

4- cg0320910

cg06217494 (cancer vs cancer) 7-94284396 (normal vs normal)

156680769 3

4- cg2228169

cg25185881 (cancer vs cancer) 7-96642037 (normal vs normal)

156681047 7

4- 8- cgl573990

cg22065614 (cancer vs cancer) (normal vs normal)

157997360 125313885 4

4- cgl792064

cgl6269431 (cancer vs cancer) 8-216578 (normal vs normal)

157997367 6

4- cg08712866 (cancer vs cancer) 8-54625046 cgl986470 (normal vs normal) 157997526 5

4- cg2290908

cgl 1163620 (cancer vs cancer) 8-6875661 (normal vs normal)

157997554 3

(normal vs normal)

4- cg0937378

cg24521633 (cancer vs cancer) 8-93156639 (cancer+normal vs

166794786 6

cancer+normal)

4- cgl9898128 (cancer vs cancer) Status - Hypo

166794971

4- 1- cg0812949

cg07893544 (cancer vs cancer) (normal vs normal)

55991782 111832109 0

4- 1- cg0325874

cg21161891 (cancer vs cancer) (normal vs normal)

55991818 151040405 9

(normal vs normal)

4- 1- cgl926402

cgl l505338 (cancer vs cancer) (cancer+normal vs

55991850 162630153 8

cancer+normal)

4- (cancer vs cancer) cgl 140613

cg00989765 1-19202951 (normal vs normal)

55991860 (cancer vs cancer) 4

4- 1- cgl610901

cg02002231 (cancer vs cancer) (normal vs normal)

81187798 197124878 2

5- cg0213809

cgO 1939274 (cancer vs cancer) 1-2040968 (normal vs normal)

127874478 8

6- 1- cg0163140

cg22143569 (cancer vs cancer) (normal vs normal)

11044541 248437212 8

6- cgl023400

cgl9365062 (cancer vs cancer) 1-39347776 (normal vs normal)

127440000 7

6- cgl781225

cg01043019 (cancer vs cancer) 1-76537463 (normal vs normal)

127440510 3

6- cg0603332

cg01555431 (cancer vs cancer) 1-86011409 (normal vs normal)

151562026 1

6- cg0439546

cg23931421 (cancer vs cancer) 1-94006866 (normal vs normal)

152957999 2

6- 10- cgl476088

cgl 1492102 (cancer vs cancer) (normal vs normal)

161352113 133960386 4

6- 10- cg0207543

cg24583770 (cancer vs cancer) (normal vs normal)

163836718 30982443 4

7- 10- cg0290891

cg03203223 (cancer vs cancer) (normal vs normal)

103630549 72578346 2

7- 10- cg0903653

cgl7362861 (cancer vs cancer) (normal vs normal)

151107257 96991505 1

7- 11- cg2299401

cg01534145 (cancer vs cancer) (normal vs normal)

28449474 105448797 8

7- 11- cg0699052

cgl 1831043 (cancer vs cancer) (normal vs normal)

28449847 130099296 9

8- 11- cgl582443

cgl8145877 (cancer vs cancer) (normal vs normal)

15397729 18617206 5

8- 11- cg2184867

cg25230074 (cancer vs cancer) (normal vs normal)

32405792 19395666 1

8- cgl609566

cg08032135 (cancer vs cancer) 11-3822594 (normal vs normal)

32406900 0

8- cgl403741

cg06926782 (cancer vs cancer) 11-9482594 (normal vs normal)

32406928 3

12- cgl706100

8-494721 cg03294066 (cancer vs cancer) (normal vs normal)

14420864 4

8- 12- cgl237893

cg09999109 (cancer vs cancer) (normal vs normal)

54164310 44949198 9

8- 12- cg2644274

cgl3096260 (cancer vs cancer) (normal vs normal)

97505764 55613318 0

8- cgl061776

cgl6935295 (cancer vs cancer) 12-6858549 (normal vs normal)

97506251 3

8- 12- cg0298107

cg04261408 (cancer vs cancer) (normal vs normal)

97506675 88428011 8 (normal vs normal)

9- 12- cg2503645 (cancer vs cancer) cg02560967 (cancer vs cancer)

112403301 95509731 6 (cancer+normal vs

cancer+normal)

9- 12- cgl431534

cgl4236735 (cancer vs cancer) (normal vs normal)

133536345 97346526 1

13- cg0324449

9-6645468 cgl 1747771 (cancer vs cancer) (normal vs normal)

21010146 4

(cancer vs cancer)

(cancer vs cancer)

13- cg0062251

9-707387 cgl3877502 (normal vs normal) (normal vs normal)

90015774 6

(cancer+normal vs

cancer+normal)

9- 14- cg0518724

cgl4170313 (cancer vs cancer) (normal vs normal)

77112896 101455260 7

14- cgl 112217

Status - Hypo (normal vs normal)

38455798 0

14- cgl382745

1-1062793 cg03520879 (cancer vs cancer) (normal vs normal)

53109146 8

(normal vs normal)

(cancer vs cancer)

14- cgl958602

1-1095607 cg02971920 (cancer vs cancer) (normal vs normal)

69254626 7

(cancer+normal vs

cancer+normal)

16- cg2251036

1-1095737 cg06767191 (cancer vs cancer) (normal vs normal)

87251839 2

(normal vs normal)

(cancer vs cancer)

1- 17- cg0153442

cg24600987 (cancer vs cancer) (normal vs normal)

17898874 18965556 3

(cancer+normal vs

cancer+normal)

1- cg0904536

cg00831127 (cancer vs cancer) 17-5990470 (normal vs normal)

23038925 0

1- 18- cgl490663

cg24580199 (cancer vs cancer) (normal vs normal)

23763081 78001859 8

1- 19- cg0277522

cg27447006 (cancer vs cancer) (normal vs normal)

23763279 57679590 3

(cancer vs cancer)

1- (cancer vs cancer) 2- cg2192688

cg22537280 (normal vs normal)

54723213 (cancer+normal vs 100939477 3

cancer+normal)

1- 2- cg2742526

cgl6693012 (cancer vs cancer) (normal vs normal)

68283821 113953981 2

10- 2- cgl714555

cgl8464364 (cancer vs cancer) (normal vs normal)

114798107 114866027 9

(cancer vs cancer)

(cancer vs cancer) 2- cgl080909

10-518370 cg26718707 (normal vs normal)

(cancer+normal vs 238006557 4

cancer+normal)

10- 2- cgl455055

cg01861509 (cancer vs cancer) (normal vs normal)

73849626 240039617 9

10- cg0161122

cgl9265913 (cancer vs cancer) 2-27630550 (normal vs normal) 81154181 3

10- cgl944658

cg02953007 (cancer vs cancer) 2-63268631 (normal vs normal)

81154192 9

11- cg2472696

cg23240479 (cancer vs cancer) 2-63606136 (normal vs normal)

126083901 5

11- (normal vs normal) 21- cgl797719

cg25892168 (normal vs normal)

130059549 (cancer vs cancer) 34601762 7

11- (normal vs normal) 22- cgl917127

cgl 1069338 (normal vs normal)

130060459 (cancer vs cancer) 38449367 2 (cancer vs cancer)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) 3- cg2731848

cgl4907310 (normal vs normal)

2287734 (cancer+normal vs 100970896 1

cancer+normal)

11- 3- cg0078979

cg24974729 (cancer vs cancer) (normal vs normal)

67764320 141329863 3

11- 3- cg0152040

cg27270565 (cancer vs cancer) (normal vs normal)

9142260 142790398 2

11- (cancer vs cancer) 3- cgl442377

cg24256772 (normal vs normal)

94275751 (cancer vs cancer) 151985433 8

12- 3- cgl737495

cg06610259 (cancer vs cancer) (normal vs normal)

122515332 158990856 8

(normal vs normal)

12- cg0899895

cgl8754342 (cancer vs cancer) 3-4856199 (normal vs normal)

14849268 0

(cancer vs cancer)

12- cgl993062

cgl9677302 (cancer vs cancer) 3-7340148 (normal vs normal)

33048259 0

12- cg2568852

cgl9013339 (cancer vs cancer) 3-73434814 (normal vs normal)

96052514 3

13- 4- cgl l31395

cg01154353 (cancer vs cancer) (normal vs normal)

44953908 147393712 1

16- (normal vs normal) 4- cgl747957

cgO 1149677 (normal vs normal)

1808230 (cancer vs cancer) 152424074 6

16- 4- cg0674893

cg27133583 (cancer vs cancer) (normal vs normal)

29300673 175239475 4

(normal vs normal)

(cancer vs cancer)

16- cg2572622

cgl0398761 (cancer vs cancer) 4-2402046 (normal vs normal)

89169289 4

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cgl775639

cg23346781 4-89084266 (normal vs normal) 1412449 (cancer+normal vs 8

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 5- cg0577062

cgl 1542336 (normal vs normal)

4042717 (cancer+normal vs 102465432 6

cancer+normal)

17- 5- cg0141967

cg25518968 (cancer vs cancer) (normal vs normal)

48845009 115696151 0

17- 5- cgl392724

cgl2235260 (cancer vs cancer) (normal vs normal)

48845052 118176275 7

17- cg2758679

cg07443932 (cancer vs cancer) 5-13664584 (normal vs normal)

48845064 7

(normal vs normal)

(cancer vs cancer)

17- 5- cgl853339

cg06909248 (cancer vs cancer) (normal vs normal)

70256462 173386190 2

(cancer+normal vs

cancer+normal)

17- cgl742767

cg21762727 (cancer vs cancer) 5-43045555 (normal vs normal)

7163136 5

(normal vs normal)

(cancer vs cancer)

17- 6- cg0653943

cgl6366685 (cancer vs cancer) (normal vs normal)

80535398 101120796 4

(cancer+normal vs

cancer+normal)

17- (normal vs normal) 6- cg0748419

cg03454705 (normal vs normal)

80535428 (cancer vs cancer) 104920530 1 (cancer vs cancer)

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

19- 6- cgl644134

cgl2028674 (cancer vs cancer) (normal vs normal)

39306244 110057745 7

(cancer+normal vs

cancer+normal)

19- 6- cgl742818

cg23263641 (cancer vs cancer) (normal vs normal)

44128109 112668163 5

19- 6- cg0602269

cg07684068 (cancer vs cancer) (normal vs normal)

46807660 117201841 8

(normal vs normal)

(cancer vs cancer)

2- 6- cgOl 14523

cg24419520 (cancer vs cancer) (normal vs normal)

106959257 150245071 2

(cancer+normal vs

cancer+normal)

2- (cancer vs cancer) 6- cg0254641

cg25890678 (normal vs normal)

112808038 (cancer vs cancer) 170487311 6

2- cg0932059

cg08280341 (cancer vs cancer) 6-31478822 (normal vs normal)

164594200 5

(normal vs normal)

(cancer vs cancer)

2- cgl803543

cgl2793924 (cancer vs cancer) 6-31929046 (normal vs normal)

17830624 5

(cancer+normal vs

cancer+normal)

2- cg0033453

cg01218350 (cancer vs cancer) 6-32712093 (normal vs normal)

210517441 2

(cancer vs cancer)

2- (cancer vs cancer) cgO 109002

cg03426602 6-39692382 (normal vs normal)

227312417 (cancer+normal vs 6

cancer+normal)

2- cg0613467

cg25599161 (cancer vs cancer) 6-9139720 (normal vs normal)

241543460 8

2- 7- cg0629463

cgl3603214 (cancer vs cancer) (normal vs normal)

85920000 123181238 0

(normal vs normal)

(cancer vs cancer)

cg2323871

2-8850020 cg00240378 (cancer vs cancer) 7-12410026 (normal vs normal)

9

(cancer+normal vs

cancer+normal)

2- (normal vs normal) 7- cg0274907

cgl2942038 (normal vs normal)

97427895 (cancer vs cancer) 133137334 3

(normal vs normal)

(cancer vs cancer)

2- 7- cgl l75712

cgl 1464842 (cancer vs cancer) (normal vs normal)

97427975 157526947 4

(cancer+normal vs

cancer+normal)

20- cg0994966

cgl9448292 (cancer vs cancer) 7-43678966 (normal vs normal)

35504064 6

20- cgl459329

cg01268752 (cancer vs cancer) 7-50529359 (normal vs normal) 43926551 0

(normal vs normal)

(cancer vs cancer)

20- cg0093326

cg25225756 (cancer vs cancer) 7-56434951 (normal vs normal)

55959405 3

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

20- (cancer vs cancer) cgl240512

cg22618720 7-57072233 (normal vs normal)

55959549 (cancer+normal vs 1

cancer+normal) 20- (normal vs normal) cg0735296

cg20726575 7-57076741 (normal vs normal) 57616191 (cancer vs cancer) 7

(cancer vs cancer)

22- (cancer vs cancer) cg0225425

cg01274916 7-63494639 (normal vs normal) 31062286 (cancer+normal vs 5

cancer+normal)

3- cg0714466

cg09081544 (cancer vs cancer) 7-6501749 (normal vs normal)

124652790 6

3- cgl 136703

cgl7778120 (cancer vs cancer) 7-65447489 (normal vs normal)

139195319 8

(cancer vs cancer)

3- (cancer vs cancer) cg0001478

cg02504622 7-6614945 (normal vs normal)

150238257 (cancer+normal vs 6

cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) cgl061964

cg09433558 7-69149951 (normal vs normal)

171412917 (cancer+normal vs 4

cancer+normal)

3- cg0210615

cg03420580 (cancer vs cancer) 7-83860330 (normal vs normal)

30730226 5

3- 8- cgl627792

cg02658330 (cancer vs cancer) (normal vs normal)

58653593 131349729 2

3- 8- cgl 171607

cg03173942 (cancer vs cancer) (normal vs normal)

72435597 142182166 3

cgl272438

4-1016081 cg27309282 (cancer vs cancer) 8-71267300 (normal vs normal)

4

(normal vs normal)

(cancer vs cancer)

4- 9- cgl391082

cg23442198 (cancer vs cancer) (normal vs normal)

187126114 137736684 2

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

4- 9- cg0447628

cg21399040 (cancer vs cancer) (normal vs normal)

187629328 140143642 6

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

4- STAD (cancer vs

cg24820270 (cancer vs cancer)

187629336 cancer)

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

4- cg25352342 (cancer vs cancer) Status - Hyper

187629387

(cancer+normal vs

cancer+normal)

4- 1- cg0742019

cg02359506 (cancer vs cancer) (cancer vs cancer)

41270335 220702225 0

(cancer vs cancer)

(cancer vs cancer) 1- cgl971296

4-6945702 cg05069807 (cancer vs cancer)

(cancer+normal vs 244013006 5

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer) cg0836644

4-6945745 cgl6574807 (cancer vs cancer) 1-29138936 (cancer+normal vs

6

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

5- cg2606855 (normal vs normal) cg00143606 (cancer vs cancer) 1-57111117

10759383 1 (cancer+normal vs cancer+normal) (cancer vs cancer)

(cancer vs cancer)

5- (cancer vs cancer) cg0968631

cg26531174 1-57111122 (cancer+normal vs

149546073 (cancer+normal vs 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- (cancer vs cancer) 10- cg2402237 (cancer vs cancer) cg09690765

149547566 (cancer+normal vs 20104497 5 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- (cancer vs cancer) 10- cgl674724

cg26722544 (cancer+normal vs

179393917 (cancer+normal vs 20104806 7

cancer+normal) cancer+normal)

(cancer vs cancer)

6- 10- cg0862559 (cancer vs cancer) cgl0846969 (cancer vs cancer)

126503271 20104948 0 (cancer+normal vs cancer+normal)

(cancer vs cancer)

6- 10- cgl256317

cgl0134496 (cancer vs cancer) (cancer+normal vs

151671694 20105641 8

cancer+normal)

(cancer vs cancer)

6- 10- cgl639779

cg24212240 (cancer vs cancer) (cancer+normal vs

155649609 28032282 4

cancer+normal)

(cancer vs cancer)

6- 10- cgl923533

cg07214314 (cancer vs cancer) (cancer+normal vs

160511937 90342899 9

cancer+normal)

6- 10- cgl819229

cg02079963 (cancer vs cancer) (cancer vs cancer)

160512064 90343204 4

(cancer vs cancer)

6- 12- cgl753564

cgl 1342941 (cancer vs cancer) (cancer+normal vs

161561121 20521463 7

cancer+normal)

6- 12- cg2025577 (cancer vs cancer) cg24880997 (cancer vs cancer)

30079662 48398370 5 (cancer vs cancer)

(normal vs normal)

(cancer vs cancer)

6- 12- cgl705496

cgO 1086672 (cancer vs cancer) (cancer vs cancer)

31123044 48398374 9

(cancer+normal vs

cancer+normal)

6- 12- cg2153380

cgl3319417 (cancer vs cancer) (cancer vs cancer)

36304456 95267307 6

(cancer vs cancer)

6- 13- cg2490946

cgl0550074 (cancer vs cancer) (cancer+normal vs

36304794 110961069 6

cancer+normal)

(cancer vs cancer)

6- 13- cgl466083

_C g04434994 (cancer vs cancer) (cancer+normal vs

36305071 28674720 9

cancer+normal)

7- 13- cg0559856

cgl4504536 (cancer vs cancer) (cancer vs cancer)

102792783 28674876 2

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

7- 14- cg0155729

cgl7677524 (cancer vs cancer) (cancer+normal vs

150069026 23822017 7

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

7- 14- cg0418420

cg05407490 (cancer vs cancer) (cancer+normal vs

23749667 96505874 8

cancer+normal)

7- 15- cg2458376

cg05000488 (cancer vs cancer) (cancer vs cancer)

23749740 23208349 6

7- (cancer vs cancer) 15- cgl 179487

cg09921682 (cancer vs cancer)

50133131 (cancer vs cancer) 28983117 7

7- (normal vs normal) 15- cg2682575

cgl6233515 (cancer vs cancer)

73408058 (cancer vs cancer) 28983120 1 (cancer vs cancer)

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

7- 15- cg0712401

cg07243141 (cancer vs cancer) (cancer vs cancer)

73408060 28983122 7

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

7- 15- cg2089925

cgl8780627 (cancer vs cancer) (cancer+normal vs

73408101 93632619 3

(cancer+normal vs cancer+normal) cancer+normal)

7- 17- cg0280408

cg20411384 (cancer vs cancer) (cancer vs cancer)

90670577 43972969 7

8- (normal vs normal) 17- cgl836801 (cancer vs cancer) cg23625106

61789727 (cancer vs cancer) 43972978 9 (cancer vs cancer)

9- 17- cg0977558

_C gl4434198 (cancer vs cancer) (cancer vs cancer)

97369302 45810865 2

(cancer vs cancer)

9- 17- cg2693277

cgl3494954 (cancer vs cancer) (cancer+normal vs

97369791 59476790 9

cancer+normal)

(cancer vs cancer)

KICH (cancer vs 17- cgl994944

(cancer+normal vs cancer) 59477557 1

cancer+normal)

(cancer vs cancer)

17- cg0936555

Status - Hyper (cancer+normal vs

59477564 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 18- cg0277418

cg07476201 (cancer+normal vs (cancer+normal vs

152538426 57364587 6

cancer+normal) cancer+normal)

(cancer vs cancer)

1- (cancer vs cancer) 19- cgl520837 (cancer vs cancer) cg24000437

152538857 (cancer+normal vs 31841555 5 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 19- cgl 119977

cgl 1979420 (cancer+normal vs (normal vs normal)

166139996 31841663 0

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- 19- cgl571126 (cancer vs cancer) cg22045253 (cancer+normal vs

17337346 31841952 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

1- (cancer vs cancer) 19- cgl414271

cgl0061342 (cancer vs cancer)

184357556 (cancer+normal vs 37957995 3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cgl251841

cg05398036 (cancer+normal vs (cancer+normal vs

186504948 109745812 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cg0939294

cg03315346 (cancer+normal vs (cancer+normal vs

19109544 109745828 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cg2265778

cg00089945 (cancer+normal vs (cancer+normal vs

222816858 180725907 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cg2457567

cg06939851 (cancer+normal vs (cancer+normal vs

226112534 180726035 6

cancer+normal) cancer+normal)

1- cg09119494 (cancer vs cancer) 2- cgl 111376 (cancer vs cancer) 23851471 (cancer+normal vs 180726247 0 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cg2627189

cg07388493 (cancer+normal vs (cancer+normal vs

39491459 180726249 1

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 2- cg0927924

cg26042300 (cancer+normal vs

40887988 (cancer+normal vs 180726252 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cg0669561

cgl2671744 (cancer+normal vs (cancer+normal vs

46859774 180726328 1

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 2- cg2609498

cg24720717 (cancer+normal vs (cancer vs cancer)

90309410 197457425 4

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cg0785375

1-9224198 cg22373770 (cancer+normal vs (cancer+normal vs

197457430 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

10- 2- cg2461347

cgl7480467 (normal vs normal) (cancer+normal vs

102588959 197458046 9

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

10- 2- cg0138167

cgl4778235 (normal vs normal) (cancer+normal vs

102589102 197458093 8

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

10- 2- cgl264469

cg08217716 (normal vs normal) (cancer+normal vs

102589250 197458104 6

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 2- cgl632965

cg23160142 (cancer+normal vs (cancer+normal vs 120154512 213403929 0

cancer+normal) cancer+normal)

(cancer vs cancer)

10- cg2474610

cg06624146 (cancer+normal vs 2-88751786 (cancer vs cancer)

128360149 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 20- cg0214593

cgl9321696 (cancer+normal vs (cancer+normal vs

129350922 13200969 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 20- cg0626243

cgl6750801 (cancer+normal vs (cancer+normal vs

129706313 13200973 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- (normal vs normal) 20- cg0949199 (normal vs normal) cg26063719

17273187 (cancer+normal vs 13200980 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 20- cg2156197

cg03127349 (cancer+normal vs (cancer+normal vs 31101116 13200992 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 20- cgl899391

cgl0772185 (cancer+normal vs (cancer+normal vs

34320548 13201456 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 22- cg0864991

10-375391 cg06193766 (cancer vs cancer)

(cancer+normal vs 24551820 9

cancer+normal)

(cancer vs cancer) 22- cg0270611

10-375830 cg08410533 (cancer vs cancer)

(cancer+normal vs 24552132 0 cancer+normal)

(cancer vs cancer)

10- 22- cg0561177

cg07232642 (cancer+normal vs

99822472 (cancer vs cancer)

24552379 9

cancer+normal)

(cancer vs cancer)

11- 3- cg0885365

cg00673646 (cancer+normal vs

59950525 (cancer vs cancer)

139654245 9

cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) cg2262396

cgl3563074 3-16554910

7728814 (cancer vs cancer)

(cancer+normal vs 7

cancer+normal)

(cancer vs cancer)

11- cg2261515

cg09140665 (cancer+normal vs 3-55521351

7960899 (cancer vs cancer)

8

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

12- cg0806524

cg08752459 (normal vs normal) 3-56502265

10022682 (cancer+normal vs

1

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

12- cg0667827

cgl2591315 (normal vs nomial) 3-56502293

10022688 (cancer+normal vs

9

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- cgl261513

cg07696842 (cancer+normal vs 3-87040286

105089508 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- cgl 109035

cg01573562 (cancer+normal vs 3-96532043

113229319 (cancer+normal vs

2

cancer+normal) cancer+normal)

(cancer vs cancer)

12- 4- cg2558317

cg03822198 (cancer+normal vs

116997535 (cancer vs cancer)

123748386 4

cancer+normal)

(cancer vs cancer)

12- 4- cg2198622

cg27080194 (cancer+normal vs

131198873 (cancer vs cancer)

141295029 5

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer)

4- cgl653410

cg23907053 (cancer+normal vs

70215816 (cancer+normal vs

166300252 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- 4- cg0288628 (cancer vs cancer) cgl 1203397 (cancer+normal vs

46870454 166300290 4 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

15- 4- cg0976760

cg08051964 (normal vs normal)

(cancer+normal vs

25330341 183370138 2

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

15- (cancer vs cancer) cgl375579

cgl6973527 4-20253514

70767570 (cancer+normal vs

(cancer+normal vs 6

cancer+normal) cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer)

(cancer vs cancer) cgl032272

cgl3427748 4-20253556

70767649 (cancer+normal vs

(cancer+normal vs 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16- cg0128177

cg02331561 (cancer+normal vs 4-20253595

2391081 (cancer+normal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer)

16- cgl319740

cglO 177032

4103492 (cancer+normal vs 4-57687839 (cancer vs cancer)

6

cancer+normal) (cancer vs cancer)

16- cg2691767 (cancer vs cancer) cg01352090 (cancer+normal vs 4-81952024

4103533 3 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

5- cg0058636

16-474271 cg09555736 (cancer+normal vs (cancer vs cancer)

132948251 5

cancer+normal)

(cancer vs cancer)

5- cgl460781

16-474430 cg02102075 (cancer+normal vs (cancer vs cancer)

157002793 2

cancer+normal)

(cancer vs cancer)

16- 5- cg2385186

cg05964640 (cancer+normal vs (cancer vs cancer)

84390897 157002805 0

cancer+normal)

(cancer vs cancer)

17- 5- cg0272506

cg02656560 (cancer+normal vs (cancer vs cancer)

19967600 157002817 9

cancer+normal)

(cancer vs cancer)

17- 5- cg0701117 (cancer vs cancer) cgl0174170 (cancer+normal vs

33473881 159343549 2 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

17- 5- cgl799632

cgl l235451 (cancer+normal vs (cancer vs cancer)

48989061 176057427 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cg0821722

cg08122232 (cancer+normal vs 5-42423615 (cancer+normal vs

74100132 7

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer)

19- (cancer vs cancer) cgl204258

cgl5746620 5-42423947 (normal vs normal)

14785849 (cancer+normal vs 7

(cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

19- cg0246632

cg09341448 (cancer+normal vs 5-79866099 (cancer vs cancer)

49164383 1

cancer+normal)

(cancer vs cancer)

19- 6- cg0699370

cgl5655714 (cancer+normal vs (cancer vs cancer)

51018365 125284359 3

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer)

2- (cancer vs cancer) cg2442887

cg20219891 6-21664652 (normal vs normal)

121496875 (cancer+normal vs 7

(cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

2- cg2062208

cg05853130 (cancer+normal vs 6-88875840 (cancer vs cancer)

138019701 9

cancer+normal)

(cancer vs cancer)

2- 7- cgl 125636

cg06354392 (cancer+normal vs (cancer vs cancer)

176970064 114562847 4

cancer+normal)

(cancer vs cancer)

2- 7- cgl397115

cgl8351329 (cancer+normal vs (cancer vs cancer)

176970508 128828460 4

cancer+normal)

(cancer vs cancer)

2- 7- cg0040584

cg09406107 (cancer+normal vs (cancer vs cancer)

236172440 128828575 3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cg0719174

cg02085953 (cancer+normal vs 7-42277375 (cancer+normal vs

97202260 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- 8- cg2701699

cgl2649683 (cancer+normal vs (cancer+normal vs

57975832 133492476 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

22- cg0345363

cgl l533712 (cancer+normal vs 8-21646662 (cancer+normal vs 46934981 8

cancer+normal) cancer+normal) (cancer vs cancer)

cg2706313

cgl5360181 (cancer+normal vs 8-38325950 (cancer vs cancer)

143567492 8

cancer+normal)

(cancer vs cancer)

cgl617468

cg23246821 (cancer+normal vs 8-41504078 (cancer vs cancer)

149095573 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer) cgl776318

cg07141504 (cancer+normal vs 8-6692148 (cancer+normal vs

194030706 8

cancer+normal) cancer+normal)

(cancer vs cancer)

4- cg0523476

cg06818159 (cancer+normal vs 8-6692470 (cancer vs cancer)

16628713 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cgl248255

cg01492656 (cancer+normal vs 8-6693103 (cancer+normal vs

40057241 7

cancer+normal) cancer+normal)

(cancer vs cancer)

4- cg23099587 (cancer+normal vs Status - Hypo

74570525

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- 1- cgl659289

cg01624414 (cancer+normal vs (cancer+normal vs

77119206 111023201 7

cancer+normal) cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) 1- cgl927509

cgl8086386 (cancer vs cancer)

162516650 (cancer+normal vs 119860821 1

cancer+normal)

(cancer vs cancer)

cgl577065

cgl9979108 (cancer+normal vs 1-12078821 (cancer vs cancer)

171870875 4

cancer+normal)

(cancer vs cancer)

cg0250650

cgl8040788 (cancer+normal vs 1-1228990 (cancer vs cancer)

173852421 1

cancer+normal)

(cancer vs cancer)

cg0738114

cg00329411 (cancer+normal vs 1-15783239 (cancer vs cancer)

55881858 1

cancer+normal)

(cancer vs cancer)

cg0205347

cgl4972576 (cancer+normal vs 1-22615900 (cancer vs cancer)

97645526 7

cancer+normal)

(cancer vs cancer)

o- 1- cgl426000

cg01889956 (cancer+normal vs (cancer vs cancer)

100650602 232692910 4

cancer+normal)

(cancer vs cancer)

o- cg0091747

cgl4951955 (cancer+normal vs 1-43228316 (cancer vs cancer)

106773949 1

cancer+normal)

(cancer vs cancer)

o- 10- cgl883402

cg02872426 (cancer+normal vs (cancer vs cancer)

110736772 103349097 9

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 10- cg2696658

cg07571531 (cancer vs cancer)

134216081 (cancer+normal vs 12709305 2

cancer+normal)

(cancer vs cancer)

o- 10- cg2281389

cgl 1387340 (cancer+normal vs (cancer vs cancer)

166970727 12874395 1

cancer+normal)

(cancer vs cancer)

o- 10- cg2339109

cg01797450 (cancer+normal vs (cancer vs cancer)

168134760 131631850 0

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 10- cg0868203

cg23756442 (cancer vs cancer)

28892465 (cancer+normal vs 43898033 6

cancer+normal)

6- cg07053841 (cancer vs cancer) 10- cgl208364 (cancer vs cancer) 29012588 (cancer+normal vs 51549656 4

cancer+normal)

(cancer vs cancer)

6- 10- cgl528408

cgl8244508 (cancer+normal vs (cancer vs cancer)

32172871 77142527 2

cancer+normal)

(cancer vs cancer)

6- 11- cgl606165 (cancer vs cancer) cgl7131579 (cancer+normal vs

33256216 115088907 6 (cancer vs cancer) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 11- cgl 196699

cg21748751 (cancer+normal vs (cancer+normal vs

35309867 15692519 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- cg0293535

cg06653004 (cancer+normal vs 12-1748816 (cancer+normal vs

50785325 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 12- cgl028387

cgl7153727 (cancer+normal vs (cancer+normal vs

50812112 59319720 1

cancer+normal) cancer+normal)

(cancer vs cancer)

6- 13- cgl 178750

cg03043157 (cancer+normal vs (cancer vs cancer)

97010903 26761337 8

cancer+normal)

(cancer vs cancer)

7- 13- cg0231914

cg05729490 (cancer+normal vs (cancer vs cancer)

27404187 99336246 9

cancer+normal)

(cancer vs cancer)

7- 14- cg0693765

cg05083033 (cancer+normal vs (cancer vs cancer)

28726216 71291951 3

cancer+normal)

(cancer vs cancer)

15- cgl932238 (cancer vs cancer)

7-5277188 cgl0229594 (cancer+normal vs

99408636 0 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

7- 15- cg2174642

cg21557473 (cancer+normal vs (cancer vs cancer)

69289866 99408804 5

cancer+normal)

(cancer vs cancer)

15- cgl381229

7-852714 cgl9239199 (cancer+normal vs (cancer vs cancer)

99409411 1

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 16- cg0932835

cg25591451 (cancer+normal vs (cancer+normal vs

99517509 29913162 6

cancer+normal) cancer+normal)

(cancer vs cancer)

8- 16- cg0090827

cg26069514 (cancer+normal vs (cancer vs cancer)

21900314 81254010 1

cancer+normal)

(cancer vs cancer)

8- 17- cgl243711

cg02458516 (cancer+normal vs (cancer vs cancer)

40602363 39024690 5

cancer+normal)

(cancer vs cancer)

9- 17- cgl345751

cgl3430755 (cancer+normal vs (cancer vs cancer)

110310795 45934681 5

cancer+normal)

(cancer vs cancer)

9- (cancer vs cancer) 17- cg0382832

cgl4341131 (cancer vs cancer)

138605049 (cancer+normal vs 70384485 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 17- cgl953640

cg03578548 (cancer+normal vs (cancer+normal vs

91267411 79431331 7

cancer+normal) cancer+normal)

19- cgl335271

Status - Hypo (cancer vs cancer)

17405195 7

(cancer vs cancer)

1- 19- cgl448168

cg22158547 (cancer+normal vs (cancer vs cancer)

223472245 42873953 9

cancer+normal)

(cancer vs cancer) 2- cg0074737

1-3129633 cg05265611 (cancer vs cancer)

(cancer+normal vs 102398839 2 cancer+normal)

(cancer vs cancer)

10- 2- cg04426802 cg0367155

(cancer+normal vs

126314680 (cancer vs cancer)

134004614 6

cancer+normal)

(cancer vs cancer)

10- cg06262069 2- cg0476897

(cancer+normal vs

77165905 (cancer vs cancer)

206545776 0

cancer+normal)

(cancer vs cancer)

11- cg06814191 cg0711907

(cancer+normal vs 2-33596547

10462924 (cancer vs cancer)

6

cancer+normal)

(cancer vs cancer)

11- cg0436421

cg04295172 (cancer+normal vs 2-45234140

108365051 (cancer vs cancer)

9

cancer+normal)

(cancer vs cancer)

11-456063 cgl6124920 cg2678430 (cancer vs cancer)

(cancer+normal vs 2-8596908

0 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

l i(cancer vs cancer) cg04725041 cg0818342

(cancer+normal vs 2-86037857

es 906084 (cancer+normal vs

5

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 20- cg22015277 cg2107321

(cancer+normal vs

66494177 (cancer vs cancer)

30866501 2

cancer+normal)

(cancer vs cancer)

12- 22- cgl5698107 cg0764149

(cancer+normal vs

110986864 (cancer vs cancer)

33195343 7

cancer+normal)

(cancer vs cancer)

12- 3- cgl3116789 cg0112335

(cancer+normal vs

111883369 (cancer vs cancer)

127394884 3

cancer+normal)

(cancer vs cancer)

12- 3- cgl 1601197 cg2476899

(cancer+normal vs

124812999 (cancer vs cancer)

127394912 9

cancer+normal)

(cancer vs cancer)

12- 3- cgl3719771 cg2592973

(cancer+normal vs

4762206 (cancer vs cancer)

127395387 1

cancer+normal)

(cancer vs cancer)

12- 3- cgl 1311280 cg2489453 (normal vs normal)

(cancer+normal vs

63088234 137717665 1 (cancer vs cancer) cancer+normal)

(cancer vs cancer) (normal vs normal)

12- cg26214431 3- cg0093344 (cancer vs cancer)

(cancer+normal vs

64240787 137892432 3 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

12- 3- cgl2552402 cg0262596

(cancer+normal vs

72083379 (cancer vs cancer)

155656364 8

cancer+normal)

(cancer vs cancer)

12- 3- cgl2202370 cg2079482

(cancer+normal vs

76428445 (cancer vs cancer)

170138205 4

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cgl6165258 cg2229197

(cancer+normal vs 3-52048820

76927207 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

12- cgO 137565

cg05381383 (cancer+normal vs 3-79026069

80309007 (cancer vs cancer)

1

cancer+normal)

(normal vs normal)

12- (cancer vs cancer)

cg25036456 cgl977146

4-2275994

95509731 (cancer vs cancer)

(cancer+normal vs 9

cancer+normal)

(cancer vs cancer)

12-966396 cg06817737 cg2202985

(cancer+normal vs 4-2276003 (cancer vs cancer)

6

cancer+normal)

13- cg02898500 (cancer vs cancer) 5- cg0087668 (cancer vs cancer) 113826554 (cancer+normal vs 121646014 1

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- 5- cg2536882

cg04310833 (cancer+normal vs (cancer+normal vs

102483074 132009352 4

cancer+normal) cancer+normal)

(cancer vs cancer)

14- cg0835789

cg09980114 (cancer+normal vs 5-42422138 (cancer vs cancer)

102669785 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- 6- cgl011133

cgl9687152 (cancer+normal vs (cancer+normal vs

102968497 105935915 5

cancer+normal) cancer+normal)

(cancer vs cancer)

14- 6- cg0196357

cg03487553 (cancer+normal vs (cancer vs cancer)

67822707 107388925 3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- cgl417889

cgl2850822 (cancer+normal vs 6-11778902 (cancer+normal vs

71239883 5

cancer+normal) cancer+normal)

(cancer vs cancer)

14- 6- cg2043338

cgl0395252 (cancer+normal vs (cancer vs cancer)

76236901 125331312 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- 6- cgl799341

cg23488578 (cancer+normal vs (cancer+normal vs

95585023 125364093 9

cancer+normal) cancer+normal)

(cancer vs cancer)

15- 6- cg0280788

cg05141289 (cancer+normal vs (cancer vs cancer)

57404080 125534847 2

cancer+normal)

(normal vs normal)

15- (cancer vs cancer) 6- cgl762003

cgO 1666796 (cancer vs cancer)

70364327 (cancer+normal vs 126384600 9

cancer+normal)

(cancer vs cancer)

16- 6- cg2179422

cg06184547 (cancer+normal vs (cancer vs cancer)

29578336 167536063 2

cancer+normal)

(cancer vs cancer)

6- cgO 164646

16-479994 cgl0357909 (cancer+normal vs (cancer vs cancer)

167536086 1

cancer+normal)

(cancer vs cancer)

16- cgl618643

cgO 1187464 (cancer+normal vs 6-32810833 (cancer vs cancer)

50351302 5

cancer+normal)

(cancer vs cancer)

16- cgl870850

cg00500540 (cancer+normal vs 6-33715942 (cancer vs cancer)

56394104 4

cancer+normal)

(cancer vs cancer)

16- cgl574527

cg01912578 (cancer+normal vs 6-41892347 (cancer vs cancer)

56398105 3

cancer+normal)

(cancer vs cancer)

16- cgl694644

cg03455024 (cancer+normal vs 6-53181687 (cancer vs cancer)

56899183 5

cancer+normal)

(cancer vs cancer)

16- cg0210627

cg06665333 (cancer+normal vs 6-75960530 (cancer vs cancer)

87873837 9

cancer+normal)

(cancer vs cancer)

17- 7- cgl390609

cgl8156845 (cancer+normal vs (cancer vs cancer) 11985185 100663185 8

cancer+normal)

(cancer vs cancer)

17- 7- cg0563019

cg04819655 (cancer+normal vs (cancer vs cancer)

81040663 100877583 2

cancer+normal)

(cancer vs cancer)

17- cg2246046

cgl4521546 (cancer+normal vs 7-1896154 (cancer vs cancer) 81045501 6

cancer+normal)

18- cg21116087 (normal vs normal) 7-1896220 cg2539763 (cancer vs cancer) 74832171 (cancer vs cancer) 6

(cancer+normal vs

cancer+normal)

(normal vs normal)

18- (cancer vs cancer) cg0239347

cgl6990945

74832261 7-2686405 (cancer vs cancer)

(cancer+normal vs 0

cancer+normal)

(cancer vs cancer)

19- cg2125758

cg06508379

19104064 (cancer+normal vs 7-2686947 (cancer vs cancer)

1

cancer+normal)

(normal vs normal)

19- (cancer vs cancer) cg0007124

cgl2249345

45316493 7-41351539 (cancer vs cancer)

(cancer+normal vs 1

cancer+normal)

(normal vs normal)

19- (cancer vs cancer) cg2388610

cg21978694

45316509 7-44438216 (cancer vs cancer)

(cancer+normal vs 1

cancer+normal)

(cancer vs cancer)

19- cg22640961 cg0297294

45316789 (cancer+normal vs 7-97834623 (cancer vs cancer)

1

cancer+normal)

(cancer vs cancer)

19- cg0194265

cg07453407

46404031 (cancer+normal vs 7-99773786 (cancer vs cancer)

4

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer)

8- cg0348331

cg09500565

100061911 (cancer+normal vs

102083111 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

2- 8- cg2598978

cg25114693

105695949 (cancer+normal vs (cancer vs cancer)

102699486 3

cancer+normal)

(cancer vs cancer)

2- 8- cgl626831

cg06852824

231582109 (cancer+normal vs (cancer vs cancer)

103491087 5

cancer+normal)

(cancer vs cancer)

2- 8- cgl851031

cg09336899

233766002 (cancer+normal vs (cancer vs cancer)

125928410 1

cancer+normal)

2- (cancer vs cancer)

8- cgl615471

cgl6900589

238617188 (cancer+normal vs (cancer vs cancer)

131368433 3

cancer+normal)

(cancer vs cancer)

20- 8- cg0073668

cg27556861

3128566 (cancer+normal vs (cancer vs cancer)

134546052 1

cancer+normal)

(cancer vs cancer)

20- 8- cg2055530

cgO1661001

44439932 (cancer+normal vs (cancer vs cancer)

145626588 5

cancer+normal)

(cancer vs cancer)

22- 8- cg2151826

cg27436324 (cancer+normal vs

35694370 (cancer vs cancer)

145721667 1

cancer+normal)

(cancer vs cancer)

3- 8- cg2607843

cg08559364

11634536 (cancer+normal vs (cancer vs cancer)

145721896 9

cancer+normal)

(cancer vs cancer)

3- cg2751231

cg07643000

11666825 (cancer+normal vs 8-27516631 (cancer vs cancer)

6

cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) cg0641530

cg07460095

132373398 (cancer+normal vs 8-37591379 (cancer+normal vs

2

cancer+normal) cancer+normal)

(cancer vs cancer)

3- cgl l36361

cgl0538433

156955923 (cancer+normal vs 8-41507621 (cancer vs cancer)

5

cancer+normal)

3- cgl3017471 (cancer vs cancer) 8-41507844 cg2146863 (cancer vs cancer) 171832308 (cancer+normal vs 4

cancer+normal)

(cancer vs cancer)

3- cgl564947

cgl3237147 (cancer+normal vs 8-41507852 (cancer vs cancer)

188745304 4

cancer+normal)

(cancer vs cancer)

3- cg0716160

cg21429725 (cancer+normal vs 8-41508618 (cancer vs cancer)

196693809 3

cancer+normal)

(cancer vs cancer)

3- cgl994506

cg24719910 (cancer+normal vs 8-41508779 (cancer vs cancer)

30691493 0

cancer+normal)

(cancer vs cancer)

3- cg0246760

cg24295890 (cancer+normal vs 8-49307089 (cancer vs cancer)

61889337 2

cancer+normal)

(cancer vs cancer)

4- cgl830358

cgl6650096 (cancer+normal vs 8-8239485 (cancer vs cancer)

140745554 1

cancer+normal)

(cancer vs cancer)

4- 9- cgl 127224

cg23329208 (cancer+normal vs (cancer vs cancer)

149360981 111616366 4

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cgl426981

cgl8334727 (cancer+normal vs 9-3899055 (cancer+normal vs

15659864 3

cancer+normal) cancer+normal)

(cancer vs cancer)

4- (cancer+normal vs

cgl6373817 (cancer+normal vs

169480345 cancer+normal)

cancer+normal)

(cancer vs cancer)

4- cg00762029 (cancer+normal vs Status - Hyper

185317438

cancer+normal)

(cancer vs cancer)

4- cg0776661 (cancer+normal vs cg02354388 (cancer+normal vs 1-26372887

185362534 2 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cg0836644

cg23289854 (cancer+normal vs 1-29138936 (cancer+normal vs

38006787 6

cancer+normal) cancer+normal)

(cancer vs cancer)

4- cg0487683 (cancer+normal vs cg09428766 (cancer+normal vs 1-57111099

73941755 5 cancer+normal) cancer+normal)

(cancer vs cancer)

4- cgl216783 (cancer+normal vs cgl4118160 (cancer+normal vs 1-57111108

77953569 0 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- cg2606855 (normal vs normal) cg25228995 (cancer+normal vs 1-57111117

139260468 1 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- cg0968631

cgl3384849 (cancer+normal vs 1-57111122 (cancer+normal vs

173307471 7

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

5- 10- cgl800290

cgl6230060 (cancer+normal vs (cancer+normal vs

80530213 135050779 9

cancer+normal) cancer+normal)

(cancer vs cancer)

5- 10- cg2402237 (cancer vs cancer) cgl9691163 (cancer vs cancer)

96304288 20104497 5 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl674724

cg25351606 (cancer+normal vs (cancer+normal vs

100917427 20104806 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl760320

cgl8202405 (cancer+normal vs (cancer+normal vs

11185142 20104935 6

cancer+normal) cancer+normal) (cancer vs cancer)

(cancer vs cancer)

6- 10- cg0862559 (cancer vs cancer) cg00489213 (cancer+normal vs

170686956 20104948 0 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 10- cgl256317

cg01550161 (cancer+normal vs (cancer+normal vs

107771148 20105641 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 10- cgl639779

cg23886314 (cancer+normal vs (cancer+normal vs

116272127 28032282 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 10- cgl923533

cgl8495781 (cancer+normal vs (cancer+normal vs

127574992 90342899 9

cancer+normal) cancer+normal)

(cancer vs cancer)

7- 11- cg0971947 (cancer+normal vs cg05600688 (cancer+normal vs

135624343 113930430 7 cancer+normal) cancer+normal)

(cancer vs cancer)

7- 12- cg2496657 (cancer+normal vs cgl 1344729 (cancer+normal vs

151335190 107713740 5 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 12- cgl753564

cg20200811 (cancer+normal vs (cancer+normal vs

23723014 20521463 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- cg2490946

7-5270512 cg21585409 (cancer+normal vs (cancer+normal vs

110961069 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- cgl466083

7-5270553 cg21764632 (cancer+normal vs (cancer+normal vs

28674720 9

cancer+normal) cancer+normal)

(cancer vs cancer)

7- 13- cgl048259 (cancer+normal vs cg09221667 (cancer+normal vs

98667581 44360259 6 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 14- cg0155729

cg08775375 (cancer+normal vs (cancer+normal vs

10454154 23822017 7

cancer+normal) cancer+normal)

(cancer vs cancer)

8- 14- cgl400513 (cancer+normal vs cgl3734860 (cancer+normal vs

109206912 36989550 9 cancer+normal) cancer+normal)

(cancer vs cancer)

8- 14- cgl099931 (cancer+normal vs cg01955203 (cancer+normal vs

124515502 36989936 2 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 14- cg0418420

cg24146714 (cancer+normal vs (cancer+normal vs

129073877 96505874 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 15- cg2089925

cg01954305 (cancer+normal vs (cancer+normal vs

135817117 93632619 3

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

8- 16- cg0618464

cg25043496 (cancer+normal vs (cancer+normal vs

142309582 88450241 7

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

8- 17- cgl805029

cgl0090414 (cancer+normal vs (cancer+normal vs

142309652 17399405 1

cancer+normal) cancer+normal)

(cancer vs cancer)

8- 17- cgl300492 (cancer+normal vs cg00718444 (cancer+normal vs

145685564 19437157 7 cancer+normal) cancer+normal)

(cancer vs cancer)

17- cg2267441 (cancer+normal vs

8-6616240 cg24485696 (cancer+normal vs

45056008 2 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 17- cg2693277

cgl4091473 (cancer+normal vs (cancer+normal vs

103062981 59476790 9

cancer+normal) cancer+normal) (cancer vs cancer)

(cancer+normal vs 17- cgl994944

(cancer+normal vs cancer+normal) 59477557 1

cancer+normal)

(cancer vs cancer)

17- cg0936555

Status - Hyper (cancer+normal vs

59477564 7

cancer+normal)

(cancer vs cancer) (normal vs normal)

1- 17- cgl656077

cg07476201 (cancer+normal vs (cancer+normal vs

152538426 79373381 4

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 17- cg0071239

cg24000437 (cancer+normal vs

152538857 (cancer+normal vs 79373624 0

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

1- 17- cg0721966

cgl 1979420 (cancer+normal vs (cancer+normal vs

166139996 79373673 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 18- cg0277418

cg22045253 (cancer+normal vs (cancer+normal vs

17337346 57364587 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

1- (cancer vs cancer) cgl768852

cgl0061342 18-6414978 (cancer+normal vs

184357556 (cancer+normal vs 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cgl647417

cg05398036 (cancer+normal vs 18-7566781 (cancer+normal vs

186504948 0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

1- 19- cgl 119977

cg03315346 (cancer+normal vs (normal vs normal)

19109544 31841663 0

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- 19- cgl571126 (cancer vs cancer) cg00089945 (cancer+normal vs

222816858 31841952 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

1- 19- cg0839781 (cancer+normal vs cg06939851 (cancer+normal vs

226112534 58514022 8 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cgl251841

cg09119494 (cancer+normal vs (cancer+normal vs

23851471 109745812 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cg0939294

cg07388493 (cancer+normal vs (cancer+normal vs

39491459 109745828 0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 2- cg2265778

cg26042300 (cancer+normal vs

40887988 (cancer+normal vs 180725907 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cg2457567

cgl2671744 (cancer+normal vs (cancer+normal vs

46859774 180726035 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cgl 111376

cg24720717 (cancer+normal vs (cancer+normal vs

90309410 180726247 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cg2627189

1-9224198 cg22373770 (cancer+normal vs (cancer+normal vs

180726249 1

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- (cancer vs cancer) 2- cg0927924

cgl7480467 (cancer+normal vs

102588959 (normal vs normal) 180726252 0

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

10- 2- cg0669561

cgl4778235 (normal vs normal) (cancer+normal vs

102589102 180726328 1

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

10- 2- cg0785375

cg08217716 (normal vs normal) (cancer+normal vs

102589250 197457430 8

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 2- cg2461347

cg23160142 (cancer+normal vs (cancer+normal vs 120154512 197458046 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 2- cg0138167

cg06624146 (cancer+normal vs (cancer+normal vs

128360149 197458093 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 2- cgl264469

cgl9321696 (cancer+normal vs (cancer+normal vs

129350922 197458104 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 2- cgl632965

cgl6750801 (cancer+normal vs (cancer+normal vs

129706313 213403929 0

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (normal vs normal) 2- cg2063730 (cancer+normal vs cg26063719

17273187 (cancer+normal vs 213403960 7 cancer+normal) cancer+normal)

(cancer vs cancer)

10- cgl945253 (cancer+normal vs cg03127349 (cancer+normal vs 2-68870499

31101116 5 cancer+normal) cancer+normal)

(cancer vs cancer)

10- cgl345128 (cancer+normal vs cgl0772185 (cancer+normal vs 2-68870812

34320548 0 cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

(cancer vs cancer) 20- cgl406011

10-375391 cg06193766 (cancer+normal vs

(cancer+normal vs 13200944 1

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

20- cgl266420

10-375830 cg08410533 (cancer+normal vs (cancer+normal vs

13200954 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 20- cg0214593

cg07232642 (cancer+normal vs (cancer+normal vs

99822472 13200969 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 20- cg0626243

cg00673646 (cancer+normal vs (cancer+normal vs

59950525 13200973 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- (cancer vs cancer) 20- cg0949199 (normal vs normal) cgl3563074

7728814 (cancer+normal vs 13200980 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 20- cg2156197

cg09140665 (cancer+normal vs (cancer+normal vs

7960899 13200992 0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

12- 20- cgl899391

cg08752459 (normal vs normal) (cancer+normal vs

10022682 13201456 8

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

12- 20- cgl550128 (cancer+normal vs cgl2591315 (cancer vs cancer)

10022688 19193060 1 cancer+normal)

(normal vs normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer)

12- 22- cg0927364

cg07696842 (cancer+normal vs

105089508 (cancer+normal vs

45403493 1

cancer+normal) cancer+normal)

(cancer vs cancer)

12- 22- cg0286964

cg01573562 (cancer+normal vs

113229319 (cancer+normal vs

45403700 9 cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cg0806524

cg03822198

116997535 (cancer+normal vs 3-56502265 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cg0667827

cg27080194

131198873 (cancer+normal vs 3-56502293 (cancer+normal vs

9

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cgl718946

cg23907053

70215816 (cancer+normal vs 3-77089110 (cancer+normal vs

5

cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) cgl261513

cgl 1203397

46870454 (cancer+normal vs 3-87040286 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer)

15- cg08051964 cg0937668

(cancer+normal vs 3-87040426 (cancer+normal vs

25330341 0 cancer+normal) cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer)

(cancer vs cancer) cgl 109035

cgl6973527

70767570 3-96532043 (cancer+normal vs

(cancer+normal vs 2

cancer+normal) cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer) 4- cgl315500

cgl3427748 (cancer+normal vs

70767649 (cancer+normal vs 121843785 1 cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) cg2743879

cg02331561

2391081 (cancer+normal vs 4-13546151 (cancer+normal vs

8

cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer)

4- cgl0177032 cgl653410

4103492 (cancer+normal vs (cancer+normal vs

166300252 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16- 4- cg0288628

cg01352090 (cancer vs cancer)

4103533 (cancer+normal vs

166300290 4 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

4- (normal vs normal)

16-474271 cg0242242

cg09555736 (cancer+normal vs (cancer+normal vs

183370059 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

4-

16-474430 cg0976760

cg02102075 (normal vs normal)

(cancer+normal vs

183370138 2 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) cgl375579

cgO5964640

84390897 (cancer+normal vs 4-20253514 (cancer+normal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cgl032272

19967600 cg02656560 (cancer+normal vs 4-20253556

4 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cg0128177

cgl0174170 (cancer+normal vs

33473881 4-20253595 (cancer+normal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cgl789182

cgl 1235451

48989061 (cancer+normal vs 4-55524400 (cancer+normal vs

0

cancer+normal) cancer+normal)

17- cg08122232 (cancer vs cancer) 4-87515467 cgl554356 (cancer+normal vs 74100132 (cancer+normal vs 6 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- (cancer vs cancer) 5- cg0468451

cgl5746620 (cancer+normal vs

14785849 (cancer+normal vs 121647858 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 5- cg0729596

cg09341448 (cancer+normal vs (cancer+normal vs

49164383 175223982 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- cg0821722

cgl5655714 (cancer+normal vs 5-42423615 (cancer+normal vs

51018365 7

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer)

2- (cancer vs cancer) cgl204258

cg20219891 5-42423947 (normal vs normal)

121496875 (cancer+normal vs 7

(cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cgl629201

cg05853130 (cancer+normal vs 5-42424356 (cancer+normal vs

138019701 6

cancer+normal) cancer+normal)

(cancer vs cancer)

2- 6- cg2482269 (cancer+normal vs cg06354392 (cancer+normal vs

176970064 125283245 6 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

2- 6- cgl076647

cgl8351329 (cancer+normal vs (cancer+normal vs

176970508 146864781 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cgl009614

cg09406107 (cancer+normal vs 6-17281838 (cancer+normal vs

236172440 5

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

2- cg2442887

cg02085953 (cancer+normal vs 6-21664652 (normal vs normal)

97202260 7

cancer+normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- cg0719174

cgl2649683 (cancer+normal vs 7-42277375 (cancer+normal vs

57975832 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

22- 8- cg0441389 (normal vs normal) cgl l533712 (cancer+normal vs

46934981 105601615 5 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

3- 8- cg0167581 (cancer+normal vs cgl5360181 (cancer+normal vs

143567492 105601641 4 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- 8- cg2701699

cg23246821 (cancer+normal vs (cancer+normal vs

149095573 133492476 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- cg0345363

cg07141504 (cancer+normal vs 8-21646662 (cancer+normal vs

194030706 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cgl776318

cg06818159 (cancer+normal vs 8-6692148 (cancer+normal vs

16628713 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cgl248255

cg01492656 (cancer+normal vs 8-6693103 (cancer+normal vs

40057241 7

cancer+normal) cancer+normal)

(cancer vs cancer)

4- cg23099587 (cancer+normal vs Status - Hypo

74570525

cancer+normal)

4- (cancer vs cancer) 1- cgl659289 (cancer vs cancer) cg01624414

77119206 (cancer+normal vs 111023201 7 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) 1- cg2041421 (cancer+normal vs cgl8086386

162516650 (cancer+normal vs 119957380 7 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

1- cg2169243

cgl9979108 (cancer+normal vs (cancer+normal vs

171870875 162219640 4

cancer+normal) cancer+normal)

(cancer vs cancer)

1- cg0720515 (cancer+normal vs cgl8040788 (cancer+normal vs

173852421 176147105 4 cancer+normal) cancer+normal)

(cancer vs cancer)

1- cg2323481 (cancer+normal vs cg00329411 (cancer+normal vs

55881858 204230657 1 cancer+normal) cancer+normal)

(cancer vs cancer)

1- cg0388509 (cancer+normal vs cgl4972576 (cancer+normal vs

97645526 207991780 8 cancer+normal) cancer+normal)

(cancer vs cancer)

o- cgl551909 (cancer+normal vs cg01889956 (cancer+normal vs 1-24833311

100650602 6 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal) cgl 120952

cgl4951955 (cancer+normal vs 1-68209155 (cancer+normal vs

106773949 1

cancer+normal) cancer+normal)

(cancer vs cancer)

o- cgl600001 (cancer+normal vs cg02872426 (cancer+normal vs 1-95639346

110736772 7 cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 10- cgl729505 (cancer+normal vs cg07571531

134216081 (cancer+normal vs 101194096 3 cancer+normal) cancer+normal)

(cancer vs cancer)

o- 10- cg2766038 (cancer+normal vs cgl 1387340 (cancer+normal vs

166970727 126714382 8 cancer+normal) cancer+normal)

(cancer vs cancer)

o- 10- cg0650724 (cancer+normal vs cg01797450 (cancer+normal vs

168134760 127569494 4 cancer+normal) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 10- cg0345809 (cancer+normal vs cg23756442

28892465 (cancer+normal vs 129105057 6 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal) o- 10- cgl397632

cg07053841 (cancer+normal vs (cancer+normal vs

29012588 34604934 4

cancer+normal) cancer+normal)

(cancer vs cancer)

o- 11- cgl588001 (cancer+normal vs cgl8244508 (cancer+normal vs

32172871 100661648 6 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) o- 11- cgl 196699

cgl7131579 (cancer+normal vs (cancer+normal vs

33256216 15692519 8

cancer+normal) cancer+normal)

(cancer vs cancer)

o- 11- cgl597486 (cancer+normal vs cg21748751 (cancer+normal vs

35309867 69464012 7 cancer+normal) cancer+normal)

(cancer vs cancer)

o- 11- cgl364159 (cancer+normal vs cg06653004 (cancer+normal vs

50785325 75528534 1 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal) o- cg2587285

cgl7153727 (cancer+normal vs 11-811669 (cancer+normal vs

50812112 2

cancer+normal) cancer+normal)

(cancer vs cancer)

o- 12- cgl892645 (cancer+normal vs cg03043157 (cancer+normal vs

97010903 110368234 0 cancer+normal) cancer+normal) (cancer vs cancer) (cancer vs cancer)

7- cg0293535

cg05729490 (cancer+normal vs 12-1748816 (cancer+normal vs

27404187 1

cancer+normal) cancer+normal)

(cancer vs cancer)

7- 12- cgl682097 (cancer+normal vs cg05083033 (cancer+normal vs

28726216 32711698 3 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

12- cgl995947

7-5277188 cgl0229594 (cancer+normal vs (cancer+normal vs

52610273 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- 12- cgl028387

cg21557473 (cancer+normal vs (cancer+normal vs

69289866 59319720 1

cancer+normal) cancer+normal)

(cancer vs cancer)

13- cg2166461 (cancer+normal vs

7-852714 cgl9239199 (cancer+normal vs

111277611 4 cancer+normal) cancer+normal)

(cancer vs cancer)

7- 13- cg0196121 (cancer+normal vs cg25591451 (cancer+normal vs

99517509 114014065 1 cancer+normal) cancer+normal)

(cancer vs cancer)

8- 13- cgl l21843 (cancer+normal vs cg26069514 (cancer+normal vs

21900314 45911764 4 cancer+normal) cancer+normal)

(cancer vs cancer)

8- 13- cg0476683 (cancer+normal vs cg02458516 (cancer+normal vs

40602363 45912168 4 cancer+normal) cancer+normal)

(cancer vs cancer)

9- 13- cg2241941 (cancer+normal vs cgl3430755 (cancer+normal vs

110310795 46093146 4 cancer+normal) cancer+normal)

(cancer vs cancer)

9- (cancer vs cancer) 15- cgl901375 (cancer+normal vs cgl4341131

138605049 (cancer+normal vs 75915192 3 cancer+normal) cancer+normal)

(cancer vs cancer)

9- 15- cgl057724 (cancer+normal vs cg03578548 (cancer+normal vs

91267411 77456283 1 cancer+normal) cancer+normal)

cg2762475 (cancer+normal vs

Status - Hypo 16-1673702

3 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 16- cg0932835

cg22158547 (cancer+normal vs (cancer+normal vs

223472245 29913162 6

cancer+normal) cancer+normal)

(cancer vs cancer)

16- cg0175078 (cancer+normal vs

1-3129633 cg05265611 (cancer+normal vs

88564747 3 cancer+normal) cancer+normal)

(cancer vs cancer)

10- 16- cg0960756 (cancer+normal vs cg04426802 (cancer+normal vs

126314680 89367323 6 cancer+normal) cancer+normal)

(cancer vs cancer)

10- 17- cg0352614 (cancer+normal vs cg06262069 (cancer+normal vs

77165905 33864734 2 cancer+normal) cancer+normal)

(cancer vs cancer)

11- cg2513640 (cancer+normal vs cg06814191 (cancer+normal vs 17-5265254

10462924 8 cancer+normal) cancer+normal)

(cancer vs cancer)

11- 17- cg0329620 (cancer+normal vs cg04295172 (cancer+normal vs

108365051 77923971 4 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cgl979087

11-456063 cgl6124920 (cancer+normal vs (cancer+normal vs

77948884 7

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 17- cgl646606 (cancer+normal vs cg04725041 (cancer+normal vs

63906084 79146774 5 cancer+normal) cancer+normal)

11- cg22015277 (cancer vs cancer) 17- cgl953640 (cancer vs cancer) 66494177 (cancer+normal vs 79431331 7 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

12- 17- cgl669075 (cancer+normal vs cgl5698107 (cancer+normal vs

110986864 79623626 3 cancer+normal) cancer+normal)

(cancer vs cancer)

12- 18- cg0014889 (cancer+normal vs cgl3116789 (cancer+normal vs

111883369 19780878 2 cancer+normal) cancer+normal)

12- (cancer+normal vs 18- cgl336021 (cancer+normal vs cgl8623355

116808922 cancer+normal) 67997425 5 cancer+normal)

(cancer vs cancer) (normal vs normal)

12- 18- cg2232498

cgl 1601197 (cancer+normal vs (cancer+normal vs

124812999 77283493 1

cancer+normal) cancer+normal)

(cancer vs cancer)

12- 19- cg2251843 (cancer+normal vs cgl3719771 (cancer+normal vs

4762206 49253931 3 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

12- 2- cg0340578

cgl 1311280 (cancer+normal vs (cancer+normal vs

63088234 103095638 1

cancer+normal) cancer+normal)

(cancer vs cancer)

12- 2- cgl921806 (cancer+normal vs cg26214431 (cancer+normal vs

64240787 181235115 7 cancer+normal) cancer+normal)

(cancer vs cancer)

12- cg0493760 (cancer+normal vs cgl2552402 (cancer+normal vs 2-23852064

72083379 9 cancer+normal) cancer+normal)

(cancer vs cancer)

12- 2- cg0882569 (cancer+normal vs cgl2202370 (cancer+normal vs

76428445 239983929 9 cancer+normal) cancer+normal)

(cancer vs cancer)

12- cgl080371 (cancer+normal vs cgl6165258 (cancer+normal vs 2-69399575

76927207 4 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- cg0818342

cg05381383 (cancer+normal vs 2-86037857 (cancer+normal vs

80309007 5

cancer+normal) cancer+normal)

(normal vs normal)

12- (cancer vs cancer) 3- cg0621852 (cancer+normal vs cg25036456

95509731 (cancer+normal vs 124284219 3 cancer+normal) cancer+normal)

(cancer vs cancer)

3- cg0540913 (cancer+normal vs

12-966396 cg06817737 (cancer+normal vs

132070595 1 cancer+normal) cancer+normal)

(cancer vs cancer)

13- 3- cgl813062 (cancer+normal vs cg02898500 (cancer+normal vs

113826554 134124275 2 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

14- 3- cg0093344 (cancer vs cancer) cg04310833 (cancer+normal vs

102483074 137892432 3 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

14- 3- cg0893238 (cancer+normal vs cg09980114 (cancer+normal vs

102669785 138078989 1 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

14- 3- cg2731656

cgl9687152 (cancer+normal vs (cancer+normal vs

102968497 149832476 7

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer) (cancer vs cancer)

14- 3- cg2193737

cg03487553 (cancer+normal vs (cancer vs cancer)

67822707 194868750 7

cancer+normal) (cancer+normal vs cancer+normal)

14- (cancer vs cancer) cg2229197 (cancer vs cancer) cgl2850822 3-52048820

71239883 (cancer+normal vs 4 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

14- cgl0395252 cg2753399 (cancer+normal vs

(cancer+normal vs 3-67691965

76236901 9

cancer+normal) cancer+normal)

(cancer vs cancer)

14- cg23488578 (cancer+normal vs 4-2439397 cg0534733 (cancer+normal vs

95585023 4

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

15- cg2660504 (cancer vs cancer) cg05141289 (cancer+normal vs 4-2439731

57404080 6 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

15- (cancer vs cancer) cg0656296

cgO 1666796 (cancer+normal vs

4-37686268

70364327 (cancer+normal vs 4 cancer+normal) cancer+normal)

(cancer vs cancer)

16- (normal vs normal) cg2455702

cg06184547 (cancer+normal vs 4-95335239

29578336 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5-

16-479994 cg2536882

cgl0357909 (cancer+normal vs (cancer+normal vs

132009352 4

cancer+normal) cancer+normal)

(cancer vs cancer)

16- cgl332523

cgO 1187464 (cancer+normal vs

(cancer+normal vs 5-1342170

50351302 1

cancer+normal) cancer+normal)

(cancer vs cancer)

16- cg0749387

cg00500540 (cancer+normal vs

(cancer+normal vs 5-1342172

56394104 4

cancer+normal) cancer+normal)

(cancer vs cancer)

16- (normal vs normal) cgl473363

cg01912578 (cancer+normal vs 5-1342200

56398105 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer)

16- (normal vs normal)

5- cg2555135

cg03455024 (cancer+normal vs

56899183 (cancer+normal vs

139079288 8

cancer+normal) cancer+normal)

(cancer vs cancer)

16- (normal vs normal) cgl627298

cg06665333 (cancer+normal vs 5-1489889

87873837 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 5- cgl555237

cgl 8156845 (cancer+normal vs 11985185 (cancer+normal vs

172117322 0

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer)

6- cgl011133

cg04819655 (cancer+normal vs

81040663 (cancer+normal vs

105935915 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cgl417889

cgl4521546 (cancer+normal vs 6-11778902

81045501 (cancer+normal vs

5

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

18- (cancer vs cancer) 6- cgl799341

cg21116087

74832171 (cancer+normal vs

(cancer+normal vs 125364093 9

cancer+normal) cancer+normal)

(normal vs normal)

18- (cancer vs cancer) (normal vs normal)

6- cg2528956

cgl6990945

74832261 (cancer+normal vs

(cancer+normal vs 136679108 9

cancer+normal) cancer+normal)

(cancer vs cancer)

19- 6- cg2141170 (cancer+normal vs cg06508379 (cancer+normal vs

19104064 138747752 5

cancer+normal) cancer+normal)

(normal vs normal)

19- (cancer vs cancer) 6- cgl029560 (cancer+normal vs cgl2249345

45316493 (cancer+normal vs 143132934 9 cancer+normal) cancer+normal)

19- cg21978694 (normal vs normal) 6- cg0552601 (cancer+normal vs 45316509 (cancer vs cancer) 170553845 5 cancer+normal)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

19- (normal vs normal) cg22640961 cg0095580

(cancer+normal vs 6-21754525

45316789 (cancer+normal vs

8

cancer+normal) cancer+normal)

(cancer vs cancer)

19- (normal vs normal) cg0846219

cg07453407 (cancer+normal vs 6-33384179

46404031 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (normal vs normal) cg09500565 cgl739187

(cancer+normal vs 6-41714182

100061911 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer)

2- 7- cgl436196

cg25114693 (cancer+normal vs

(cancer+normal vs

105695949 100883552 9

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (normal vs normal) cg0720261

cg06852824 (cancer+normal vs 7-1142643

231582109 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (normal vs normal) cgl829796

cg09336899 (cancer+normal vs 7-1142765

233766002 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

2- cg2005441

cgl6900589 (cancer+normal vs

(cancer+normal vs 7-1143524

238617188 2

cancer+normal) cancer+normal)

(cancer vs cancer)

20- cg27556861 7- cgl553547 (cancer+normal vs

(cancer+normal vs

3128566 139332087 1

cancer+normal) cancer+normal)

(cancer vs cancer)

20- (normal vs normal) cg01661001 cg0503661

(cancer+normal vs 7-77552789

44439932 (cancer+normal vs

5

cancer+normal) cancer+normal)

(cancer vs cancer)

22- (normal vs normal) cgl521173

cg27436324 (cancer+normal vs 7-97935756

35694370 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

3- (normal vs normal) cgl059249

cg08559364 (cancer+normal vs 7-97935764

11634536 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer)

8- cg0348331

cg07643000

11666825 (cancer+normal vs

102083111 4 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

cg0379622 (cancer+normal vs cg07460095 (cancer+normal vs 8-30383628

132373398 4 cancer+normal) cancer+normal)

(cancer vs cancer)

3- cg2697775

cgl0538433 (cancer+normal vs

(cancer+normal vs 8-37518651

156955923 9

cancer+normal) cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) cgl3017471 cg0641530

(cancer+normal vs 8-37591379

171832308 (cancer+normal vs

2

cancer+normal) cancer+normal)

(cancer vs cancer)

3- cgl045659

cgl3237147 (cancer+normal vs

(cancer+normal vs 8-71279864

188745304 1

cancer+normal) cancer+normal)

(cancer vs cancer)

3- cgl211287

cg21429725 (cancer+normal vs

(cancer+normal vs 8-86112931

196693809 0

cancer+normal) cancer+normal)

(cancer vs cancer)

3- cgl414563

cg24719910 (cancer+normal vs

(cancer+normal vs 8-86112946

30691493 2

cancer+normal) cancer+normal)

(cancer vs cancer)

3- 9- cgl446860

cg24295890 (cancer+normal vs

(cancer+normal vs

61889337 137255666 5

cancer+normal) cancer+normal)

4- cgl6650096 (cancer vs cancer) 9-3899055 cgl426981 (cancer vs cancer) 140745554 (cancer+normal vs 3 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

4- cg0327564 (cancer+normal vs cg23329208 (cancer+normal vs 9-96940848

149360981 8 cancer+normal) cancer+normal)

(cancer vs cancer)

4- cgl8334727 (cancer+normal vs (normal vs normal)

15659864

cancer+normal)

(cancer vs cancer)

4- cgl6373817 (cancer+normal vs Status - Hyper

169480345

cancer+normal)

(cancer vs cancer)

4- 1- cg2410663

cg00762029 (cancer+normal vs (normal vs normal)

185317438 116381475 6

cancer+normal)

(cancer vs cancer)

4- 1- cg0747967

cg02354388 (cancer+normal vs (normal vs normal)

185362534 236227686 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

4- cg2606855 (normal vs normal) cg23289854 (cancer+normal vs 1-57111117

38006787 1 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

4- cgl832256

cg09428766 (cancer+normal vs 1-91182777 (normal vs normal)

73941755 9

cancer+normal)

(cancer vs cancer)

4- lO- cgl517313

cgl4118160 (cancer+normal vs (normal vs normal)

77953569 l l 9000638 4

cancer+normal)

(cancer vs cancer)

5- 10- cg2749175

cg25228995 (cancer+normal vs (normal vs normal)

139260468 131988874 9

cancer+normal)

(cancer vs cancer)

5- 10- cg2548587

cgl3384849 (cancer+normal vs (normal vs normal)

173307471 134600998 5

cancer+normal)

(cancer vs cancer)

5- 10- cg0963972

cgl6230060 (cancer+normal vs (normal vs normal)

80530213 134901294 5

cancer+normal)

(cancer vs cancer)

6- 10- cgl582578

cg25351606 (cancer+normal vs (normal vs normal)

100917427 134901297 6

cancer+normal)

(cancer vs cancer) (normal vs normal)

6- 10- cgl800290

cgl8202405 (cancer+normal vs (cancer+normal vs

11185142 135050779 9

cancer+normal) cancer+normal)

(cancer vs cancer)

6- 10- cg0937303

cg00489213 (cancer+normal vs (normal vs normal)

170686956 46970625 7

cancer+normal)

(cancer vs cancer)

7- 11- cgl204083

cg01550161 (cancer+normal vs (normal vs normal)

107771148 112833773 0

cancer+normal)

(cancer vs cancer)

7- 11- cgl871863

cg23886314 (cancer+normal vs (normal vs normal)

116272127 118023765 4

cancer+normal)

(cancer vs cancer)

7- cgl643772

cgl8495781 (cancer+normal vs 11-7273046 (normal vs normal)

127574992 8

cancer+normal)

(cancer vs cancer)

7- cgl856032

cg05600688 (cancer+normal vs 11-7273148 (normal vs normal)

135624343 8

cancer+normal)

(cancer vs cancer)

7- 12- cg0694791

cgl 1344729 (cancer+normal vs (normal vs normal)

151335190 50297793 3

cancer+normal)

7- cg20200811 (cancer vs cancer) 13- cg0410196 (normal vs normal) 23723014 (cancer+normal vs 20806477 9

cancer+normal)

(cancer vs cancer)

13- cg0714871

7-5270512 cg21585409 (cancer+normal vs (normal vs normal)

20806539 6

cancer+normal)

(cancer vs cancer)

13- cg2536956

7-5270553 cg21764632 (cancer+normal vs (normal vs normal)

20806543 0

cancer+normal)

(cancer vs cancer)

7- 14- cg0530238

cg09221667 (cancer+normal vs (normal vs normal)

98667581 52734525 6

cancer+normal)

(cancer vs cancer)

8- 14- cg2522507

cg08775375 (cancer+normal vs (normal vs normal)

10454154 90528983 3

cancer+normal)

(cancer vs cancer)

8- 15- cg0428316 (cancer vs cancer) cgl3734860 (cancer+normal vs

109206912 29862517 2 (normal vs normal) cancer+normal)

(cancer vs cancer)

8- 15- cg0001252

cg01955203 (cancer+normal vs (normal vs normal)

124515502 98503952 2

cancer+normal)

(cancer vs cancer)

8- 15- cg0343774

cg24146714 (cancer+normal vs (normal vs normal)

129073877 99193247 8

cancer+normal)

(cancer vs cancer)

8- 15- cgl546087

cg01954305 (cancer+normal vs (normal vs normal)

135817117 99193929 2

cancer+normal)

(cancer vs cancer)

8- cg0541712

cg25043496 (cancer+normal vs 16-1968709 (normal vs normal)

142309582 7

cancer+normal)

(cancer vs cancer)

8- 16- cg2701413

cgl0090414 (cancer+normal vs (normal vs normal)

142309652 25703528 5

cancer+normal)

(cancer vs cancer)

8- 16- cg0091688

cg00718444 (cancer+normal vs (normal vs normal)

145685564 56666334 4

cancer+normal)

(cancer vs cancer)

16- cg0735584

8-6616240 cg24485696 (cancer+normal vs (normal vs normal)

67427339 1

cancer+normal)

(cancer vs cancer) (normal vs normal)

16- cg0618464

cgl4091473 (cancer+normal vs (cancer+normal vs

103062981 88450241 7

cancer+normal) cancer+normal)

KIRC_KIRP (cancer vs lecg0189866

cancer) go (normal vs normal)

114063 1

16- cg0901263

Status - Hyper (normal vs normal)

90114173 3

(normal vs normal)

17- cgl805029

1-1072642 cg22433276 (cancer vs cancer) (cancer+normal vs

17399405 1

cancer+normal)

(cancer vs cancer)

1- (cancer vs cancer) cgl876536

cg08911820 17-31528 (normal vs normal)

110026001 (cancer+normal vs 6

cancer+normal)

1- 17- cg2470473 (cancer vs cancer) cg07139440 (cancer vs cancer)

151030981 42061328 0 (normal vs normal)

(cancer vs cancer)

1- 17- cg2076917

cg00868131 (cancer+normal vs (normal vs normal)

54952901 44928516 7

cancer+normal)

(cancer vs cancer)

1- 17- cg0806772

cg21850722 (cancer+normal vs (normal vs normal)

64558474 44928967 1

cancer+normal)

10- cgl 1579421 (cancer vs cancer) 17- cgl463090 (normal vs normal) 134211857 44928992 5

(cancer vs cancer) (normal vs normal)

10- 17- cgl656077

cg24085039 (cancer+normal vs (cancer+normal vs

134211908 79373381 4

cancer+normal) cancer+normal)

(normal vs normal)

10- 17- cg0721966

cgl0982433 (cancer vs cancer) (cancer+normal vs

16563821 79373673 7

cancer+normal)

(normal vs normal)

11- (cancer vs cancer) cgl768852

cgl5999356 18-6414978 (cancer+normal vs

101990755 (normal vs normal) 5

cancer+normal)

11- 18- cg0350200

cgl7637327 (cancer vs cancer) (normal vs normal)

123431162 74962133 2

11- cgl364770

cgl5005677 (cancer vs cancer) 19-1567517 (normal vs normal)

45918197 6

(cancer vs cancer) (cancer vs cancer)

11- 19- cgl 119977

cg02692785 (cancer vs cancer) (normal vs normal)

84148821 31841663 0

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- 19- cgl027622

cg03800721 (normal vs normal) (normal vs normal)

120525338 33685817 7

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cg0414879

cg25969992 19-460934 (normal vs normal)

121088408 (cancer+normal vs 4

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cg2192870

cgl9495013 19-822086 (normal vs normal)

52214119 (cancer+normal vs 1

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) 2- cg2167837

cg07375978 (normal vs normal)

52214320 (cancer+normal vs 115919009 7

cancer+normal)

(cancer vs cancer)

12- 2- cg2441651

cg05238741 (cancer+normal vs (normal vs normal)

52214758 176994764 3

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) 2- cg0509938

cgl2232783 (normal vs normal)

54422127 (cancer+normal vs 177053292 7

cancer+normal)

(cancer vs cancer)

12- (normal vs normal) cgl066090

cg04576672 2-27341795 (normal vs normal)

54422239 (cancer+normal vs 9

cancer+normal)

(cancer vs cancer)

(normal vs normal)

12- (cancer vs cancer) 20- cgl406011

cg27441225 (cancer+normal vs

54422350 (cancer+normal vs 13200944 1

cancer+normal) cancer+normal)

(normal vs normal)

12- 20- cgl266420

cgl l941633 (cancer vs cancer) (cancer+normal vs

54422447 13200954 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- (cancer vs cancer) 20- cg0949199 (normal vs normal) cg22378817

54422488 (cancer+normal vs 13200980 1 (cancer+normal vs

cancer+normal) cancer+normal)

12- 20- cgl235800

cg00576279 (cancer vs cancer) (normal vs normal)

54427293 25566178 0

12- cgl6983211 (cancer vs cancer) 20- cgl266446 (normal vs normal) 54427636 (cancer vs cancer) 61051021 4

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) 20- cg2026573 (cancer vs cancer) cgl5700739

54427700 (cancer+normal vs 61051032 3 (normal vs normal) cancer+normal)

(cancer vs cancer)

12- 20- cg0248446

cg03416628 (cancer+normal vs (normal vs normal)

54446505 61051036 9

cancer+normal)

12- 20- cgl498098 (cancer vs cancer) cg25975485 (cancer vs cancer)

54446537 61051039 3 (normal vs normal)

(cancer vs cancer)

12- 21- cg2034050

cg08712054 (cancer+normal vs (normal vs normal)

54446576 34442377 8

cancer+normal)

(cancer vs cancer)

12- 3- cg0260452

cg03782861 (cancer+normal vs (normal vs normal)

97857511 128720884 4

cancer+normal)

12- 3- cgl422618

cg01473955 (cancer vs cancer) (normal vs normal)

99287876 158450251 2

(cancer vs cancer)

13- (cancer vs cancer) 3- cg2145345

cgO 1866427 (normal vs normal)

113598068 (cancer+normal vs 181414237 1

cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) 3- cgl729258

cg02223067 (normal vs normal)

113623233 (cancer+normal vs 184287196 3

cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) cg2007515

cgl6737670 4-11430717 (normal vs normal)

113623300 (cancer+normal vs 6

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- 4- cg2159923

cgOO 127894 (normal vs normal) (normal vs normal)

113623639 118006619 0

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) 4- cgl763257

cgl5179805 (normal vs normal)

113623659 (cancer+normal vs 119274013 9

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- 4- cg0226822

cg09678836 (normal vs normal) (normal vs normal)

113623844 141490037 9

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

17- 4- cg2071039

cg05090106 (cancer+normal vs (normal vs normal)

18908220 170947395 4

cancer+normal)

(cancer vs cancer)

(normal vs normal)

17- (cancer vs cancer) 4- cg0242242

cgl4807365 (cancer+normal vs

18908235 (cancer+normal vs 183370059 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- (cancer vs cancer) 4- cg0976760 (normal vs normal) cg22220165

18908242 (cancer+normal vs 183370138 2 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cgl537935

cgl6293732 4-25032556 (normal vs normal)

35289543 (cancer+normal vs 4

cancer+normal) 17- cg2630690

cg06094642 (cancer vs cancer) 4-37455485 (normal vs normal)

35290307 9

(cancer vs cancer)

17- cg0719501

cg05279092 (cancer+normal vs 5-11904114 (normal vs normal)

35290458 1

cancer+normal)

17- 5- cg2490881

cgl2655190 (cancer vs cancer) (normal vs normal)

35290523 132947725 4

(cancer vs cancer)

17- 5- cgl282507

cgl9502920 (cancer+normal vs (normal vs normal)

35290635 148033708 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cgl204258

cgl7231347 (cancer vs cancer) 5-42423947 (normal vs normal)

35290822 7

(cancer+normal vs cancer+normal)

(cancer vs cancer)

17- cgl581450

cg07103093 (cancer+normal vs 5-50694985 (normal vs normal)

35297752 4

cancer+normal)

(cancer vs cancer)

17- (normal vs normal) cg2659000

cg04588165 5-72512115 (normal vs normal)

35300874 (cancer+normal vs 3

cancer+normal)

(normal vs normal)

17- 6- cgl076647

cg23349301 (cancer vs cancer) (cancer+normal vs

46697115 146864781 5

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

17- cg2442887

cg24042517 (cancer+normal vs 6-21664652 (normal vs normal)

46704410 7

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

17- cg2302757

cgl0342722 (cancer+normal vs 6-30043194 (normal vs normal)

55056066 4

cancer+normal)

17- (cancer vs cancer) cg0555218 (cancer vs cancer) cg06683719 6-42928497

5673550 (cancer vs cancer) 3 (normal vs normal)

17- cgl433888

cg25753722 (cancer vs cancer) 6-42928500 (normal vs normal)

70498417 7

(cancer vs cancer)

17- (cancer vs cancer) 7- cgl048566

cg21068610 (normal vs normal)

7790179 (cancer+normal vs 121946036 4

cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) 7- cgl702583

cgl8596381 (normal vs normal)

11199917 (cancer+normal vs 123673331 5

cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) 7- cgl550615 (cancer vs cancer) cgl9751789

11199944 (cancer+normal vs 139168484 7 (normal vs normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cg2612298

cgl2013591 7-38671001 (normal vs normal)

11199965 (cancer+normal vs 0

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cg0309883

cg00506866 7-89748686 (normal vs normal)

10263480 (cancer+normal vs 7

cancer+normal)

(cancer vs cancer)

2- 8- cg0441389 (normal vs normal) cg22365240 (cancer vs cancer)

105374995 105601615 5 (cancer+normal vs cancer+normal) 2- 8- cgl433842

cg09597470 (cancer vs cancer) (normal vs normal)

134024618 120220799 5

(cancer vs cancer)

(cancer vs cancer)

2- cg2053698 (normal vs normal) cg01598144 (cancer+normal vs 8-13134166

21856440 3 (cancer+normal vs

cancer+normal)

cancer+normal)

2- cg2441054

cgl7845266 (cancer vs cancer) 8-26371551 (normal vs normal)

238769060 6

(cancer vs cancer)

2- cg0263731

cg08863459 (cancer+normal vs 8-38965252 (normal vs normal)

72372965 8

cancer+normal)

2- cgl845491

cg04965934 (cancer vs cancer) 8-74005562 (normal vs normal)

73151201 6

2- (cancer vs cancer) cg2622001

cgl6781647 8-76320150 (normal vs normal)

73151595 (normal vs normal) 8

(cancer vs cancer)

2- 9- cg0445505

cg00486564 (cancer+normal vs (normal vs normal)

73151879 139085579 8

cancer+normal)

2- cg2040152

cgl5270150 (cancer vs cancer) 9-90112711 (normal vs normal)

73151966 1

(cancer vs cancer)

3- (cancer vs cancer) cgl368572

cg00589251 9-90589530 (normal vs normal)

132036382 (cancer+normal vs 7

cancer+normal)

(cancer vs cancer)

4- (cancer vs cancer) cgl027260

cgl5903185 9-95947146 (normal vs normal)

111530471 (cancer+normal vs 1

cancer+normal)

(cancer vs cancer)

4- cg01612366 (cancer+normal vs Status - Hypo

14113465

cancer+normal)

5- 1- cg2433721 (normal vs normal) cg25780607 (cancer vs cancer)

149682233 155881944 5 (cancer vs cancer)

(cancer vs cancer) (normal vs normal)

1- cg2169243

5-475085 cgl5084390 (cancer+normal vs (cancer+normal vs

162219640 4

cancer+normal) cancer+normal)

(cancer vs cancer)

1- cgl086175

5-475205 cg21743597 (cancer+normal vs (normal vs normal)

192544716 1

cancer+normal)

5- (cancer vs cancer) 1- cgl886525

cgl8242030 (normal vs normal)

58335271 (normal vs normal) 204329775 7

5- (cancer vs cancer) 1- cg0229088

cg22078451 (normal vs normal)

58335681 (normal vs normal) 206317854 0

(cancer vs cancer)

(cancer vs cancer)

5- 1- cgl614079

cg02632185 (normal vs normal) (normal vs normal)

66299786 211384247 4

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) 1- cgl513320

cgl8118497 (normal vs normal)

66299875 (cancer+normal vs 248852044 1

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- cg0999314

cgl7449851 (normal vs normal) 1-25291905 (normal vs normal)

66300406 5

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) cgl989711

cgl 1831286 1-26083702 (normal vs normal)

66300433 (normal vs normal) 3

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- cg2248144

cg27116842 (normal vs normal) 1-27480668 (normal vs normal)

66300503 8

(cancer+normal vs

cancer+normal)

(cancer vs cancer) (normal vs normal)

6- cgl 120952

cg01269795 (cancer+normal vs 1-68209155 (cancer+normal vs

26440101 1

cancer+normal) cancer+normal) cg2144313

7-1271604 cg07074316 (cancer vs cancer) 1-7201539 (normal vs normal)

3

(cancer vs cancer)

10- cgl488482

7-1288184 cgl6275882 (cancer+normal vs (normal vs normal)

14603607 8

cancer+normal)

(cancer vs cancer) (normal vs normal)

7- 10- cgl397632

cgl9412964 (cancer+normal vs (cancer+normal vs

151328093 34604934 4

cancer+normal) cancer+normal)

(cancer vs cancer)

11- cgl026400

7-1708823 cgl7202717 (cancer+normal vs (normal vs normal)

110198965 3

cancer+normal)

(cancer vs cancer)

7- (cancer vs cancer) cg2470225

cg08986767 11-3240068 (normal vs normal)

92747308 (cancer+normal vs 3

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cg0137236

cg07554329 (normal vs normal)

107669778 (cancer+normal vs 48041783 6

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cg0392881

cgl7136799 (normal vs normal)

107669783 (cancer+normal vs 59634276 2

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) cg2413597

cg26622232 11-6767826 (normal vs normal)

107669787 (cancer+normal vs 7

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cgl391202

cgl7176732 (normal vs normal)

107669856 (cancer+normal vs 72759293 7

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cgl916499

cgl7212289 (normal vs normal)

107669906 (cancer+normal vs 76818702 7

cancer+normal)

(cancer vs cancer)

(normal vs normal)

8- (cancer vs cancer) cg2587285

cgl6326979 11-811669 (cancer+normal vs

107670161 (cancer+normal vs 2

cancer+normal) cancer+normal)

(cancer vs cancer)

8- 12- cgl527837

cg00298796 (cancer+normal vs (normal vs normal)

107670358 131576088 4

cancer+normal)

8- 12- cg0825190

cgl9413417 (cancer vs cancer) (normal vs normal)

55294536 15114904 1

(cancer vs cancer)

8- (cancer vs cancer) cg2112900

cgl3242160 12-4023078 (normal vs normal)

55294610 (cancer+normal vs 6

cancer+normal)

(cancer vs cancer)

(normal vs normal)

8- (cancer vs cancer) 12- cgl995947

cg07664990 (cancer+normal vs

55294721 (cancer+normal vs 52610273 7

cancer+normal) cancer+normal) (cancer vs cancer)

8- 12- cg0460987

cg25766247 (cancer+normal vs (normal vs normal)

59714165 70763703 5

cancer+normal)

14- cgl564530

8-9760427 cgl5526246 (cancer vs cancer) (normal vs normal)

75988747 9

(cancer vs cancer)

15- cg0496798

8-9760528 cg00528902 (cancer+normal vs (normal vs normal)

31781955 2

cancer+normal)

15- cg0769505

8-9761905 cg06292304 (cancer vs cancer) (normal vs normal)

95803603 8

(cancer vs cancer)

9- 16- cg0373838

cgl3914324 (cancer+normal vs (normal vs normal)

79320026 84628969 4

cancer+normal)

16- cgl667165

Status - Hypo (normal vs normal)

85009995 2

(cancer vs cancer)

1- cgl756034

cg00902464 (cancer+normal vs 17-684490 (normal vs normal)

101094117 0

cancer+normal)

1- 17- _C gl034447

cgl7475583 (cancer vs cancer) (normal vs normal)

180278787 81006524 7

(cancer vs cancer) (normal vs normal)

18- cg2232498

1-2026193 cg22712840 (cancer+normal vs (cancer+normal vs

77283493 1

cancer+normal) cancer+normal)

1- cgl457976

cgl5542880 (cancer vs cancer) 18-8364304 (normal vs normal)

205114634 9

(cancer vs cancer)

(normal vs normal)

1- (cancer vs cancer) 2- cg0340578

cgl0325088 (cancer+normal vs

217724849 (cancer+normal vs 103095638 1

cancer+normal) cancer+normal)

(cancer vs cancer)

cgl385133

1-2427655 cgl0219816 (cancer+normal vs 2-10686975 (normal vs normal)

4

cancer+normal)

(cancer vs cancer)

1- cg0976122

cgl2081359 (cancer+normal vs 2-10687042 (normal vs normal)

25069665 4

cancer+normal)

(cancer vs cancer)

2- cg2062533

1-2996949 cg22506548 (cancer+normal vs (normal vs normal)

152991620 4

cancer+normal)

(cancer vs cancer)

2- cgl217767

1-3162454 cgl2800122 (cancer+normal vs (normal vs normal)

158300475 7

cancer+normal)

(cancer vs cancer)

1- 2- cgl055941

cgl 5187606 (cancer+normal vs (normal vs normal)

47656853 158300485 6

cancer+normal)

(cancer vs cancer)

1- 2- cg0391505

cgl7904129 (cancer+normal vs (normal vs normal)

54195800 158301005 5

cancer+normal)

(cancer vs cancer)

1- 2- cg2107495

cg27311970 (cancer+normal vs (normal vs normal)

54195830 203044287 9

cancer+normal)

(cancer vs cancer)

1- 2- cg0646972

cg25011368 (cancer+normal vs (normal vs normal)

55317286 242483467 6

cancer+normal)

(cancer vs cancer)

1- cg2184694

cgl 1832870 (cancer+normal vs 2-33500889 (normal vs normal)

81001617 9

cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) cgl009975

cg21039563 2-68348796 (normal vs normal)

64323816 (cancer+normal vs 8

cancer+normal)

12- cgl4400030 (cancer vs cancer) 20- cg0584053 (normal vs normal) 122498111 (cancer+normal vs 31755943 3

cancer+normal)

12- 20- cgl545703 (normal vs normal) cg23521905 (cancer vs cancer)

129298690 62562848 7 (cancer vs cancer)

(cancer vs cancer)

12- 3- cg0491561

cg00230120 (cancer+normal vs (normal vs normal)

1609346 124304960 8

cancer+normal)

12- 3- cg2489453 (normal vs normal) cgl2664938 (cancer vs cancer)

40622688 137717665 1 (cancer vs cancer)

(cancer vs cancer)

12- (cancer vs cancer) 3- cg0040511

cg24859375 (normal vs normal)

7121914 (cancer+normal vs 137728329 2

cancer+normal)

(cancer vs cancer) (normal vs normal)

13- (cancer vs cancer) 3- cg0093344 (cancer vs cancer) cg21980364

111880998 (cancer+normal vs 137892432 3 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

13- 3- cg2731656

cg05508408 (cancer+normal vs (cancer+normal vs 114138019 149832476 7

cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) 3- cg0360366

cg21238257 (normal vs normal)

114138260 (cancer+normal vs 169896616 9

cancer+normal)

(normal vs normal) (cancer vs cancer)

13- 3- cg2193737

cg24215635 (cancer vs cancer) (cancer vs cancer)

30074671 194868750 7

(cancer+normal vs cancer+normal)

(normal vs normal)

(cancer vs cancer)

13- cg2490148

cg20278383 (cancer vs cancer) 3-41121968 (normal vs normal)

96086098 8

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

13- cg0281069

cg26557005 (cancer+normal vs 3-54962954 (normal vs normal)

96086249 2

cancer+normal)

(cancer vs cancer)

13- cg2155058

cgl 1862665 (cancer+normal vs 3-65755382 (normal vs normal)

97980712 0

cancer+normal)

14- cg0502931

cg01655958 (cancer vs cancer) 4-22476976 (normal vs normal)

73709663 2

(normal vs normal)

(cancer vs cancer)

14- cg2660504 (cancer vs cancer) cg02212698 (cancer+normal vs 4-2439731

89628141 6 (cancer+normal vs cancer+normal)

cancer+normal)

14- cgl208646

cg21898844 (cancer vs cancer) 4-2814064 (normal vs normal)

89628169 4

(cancer vs cancer)

14- cgl556905

cgl8518804 (cancer+normal vs 4-2814122 (normal vs normal)

91275103 2

cancer+normal)

(cancer vs cancer)

14- cg0386298

cg24180006 (cancer+normal vs 4-76596784 (normal vs normal)

99893325 7

cancer+normal)

(normal vs normal)

15- cg2455702

cg21617870 (cancer vs cancer) 4-95335239 (cancer+normal vs

64525039 7

cancer+normal)

15- 5- cg0485521

cgOl 156844 (cancer vs cancer) (normal vs normal)

85520317 118609467 6

16- 5- cg2117660

cg03928410 (cancer vs cancer) (normal vs normal) 15127121 132698273 3 (cancer vs cancer) (normal vs normal)

16- cgl473363

cg03245889 (cancer+normal vs 5-1342200 (cancer+normal vs

15127172 7

cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

16- (cancer vs cancer) 5- cg2555135

cg06978461 (cancer+normal vs

15127193 (cancer+normal vs 139079288 8

cancer+normal) cancer+normal)

(normal vs normal)

16- cgl627298

cg05967340 (cancer vs cancer) 5-1489889 (cancer+normal vs

54146616 1

cancer+normal)

(cancer vs cancer)

16- 5- cg2696772

cg00879840 (cancer+normal vs (normal vs normal)

78323024 169617918 3

cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) cgl397698

cg03212183 5-38607402 (normal vs normal)

81565917 (cancer+normal vs 8

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cg2645316

cgl8449048 5-57787167 (normal vs normal)

18854760 (cancer+normal vs 9

cancer+normal)

(normal vs normal)

17- (cancer vs cancer) 6- cg0535766

cg00306284 (normal vs normal)

18855313 (cancer+normal vs 105750581 0

cancer+normal)

(normal vs normal)

17- (cancer vs cancer) 6- cgl016439

cg09632029 (normal vs normal)

18855506 (cancer+normal vs 119032202 3

cancer+normal)

(cancer vs cancer)

17- cg0791292

cg03950716 (cancer+normal vs 6-13274314 (normal vs normal)

40064155 2

cancer+normal)

(cancer vs cancer) (normal vs normal)

17- 6- cg2528956

cg20818528 (cancer+normal vs (cancer+normal vs

4510743 136679108 9

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 6- cg2077819

cg00349608 (cancer+normal vs (normal vs normal)

4520467 148020881 9

cancer+normal)

(cancer vs cancer)

17- 6- cg2183921

cg08137716 (cancer+normal vs (normal vs normal)

46871905 167508041 1

cancer+normal)

(cancer vs cancer)

17- 6- cgl615136

cg09777416 (cancer+normal vs (normal vs normal)

7225013 167508053 2

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 6- cg0886437

cg06975080 (normal vs normal)

78700928 (cancer+normal vs 168107203 5

cancer+normal)

(normal vs normal)

17- cg0095580

cgl0790704 (cancer vs cancer) 6-21754525 (cancer+normal vs

78701084 8

cancer+normal)

(cancer vs cancer)

19- cg0954889

cgl 1883009 (cancer+normal vs 6-32028946 (normal vs normal)

13198960 3

cancer+normal)

(cancer vs cancer)

19- cg0089810

cgl 1656553 (cancer+normal vs 6-32029152 (normal vs normal)

1424658 2

cancer+normal)

(cancer vs cancer) (normal vs normal)

2- cg0846219

cg01441308 (cancer+normal vs 6-33384179 (cancer+normal vs

127811853 4

cancer+normal) cancer+normal)

2- cg26015513 (cancer vs cancer) 6-41703872 cgl449002 (normal vs normal) 201218948 (cancer vs cancer) 5

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

2- (normal vs normal) cgl739187

cg05148385 (cancer+normal vs 6-41714182

213950646 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl063272

cg09473180 6-49833873

217403190 (normal vs normal)

(cancer+normal vs 2

cancer+normal)

2- cgl078425

cg02116856 (cancer vs cancer) 6-56711206

223806495 (normal vs normal)

8

(cancer vs cancer)

2- (normal vs normal) cg0720261

cgl7963548 (cancer+normal vs 7-1142643

224824723 (cancer+normal vs

0

cancer+normal) cancer+normal)

2- (normal vs normal) cgl829796

cgl6720807 (cancer vs cancer) 7-1142765

75786714 (cancer+normal vs

0

cancer+normal)

20- cgl592047

cgl5821605 (cancer vs cancer) 7-23827492

16289592 (normal vs normal)

2

(cancer vs cancer)

20- (normal vs normal)

(cancer vs cancer) cg0503661

cg21209310 7-77552789

6025272 (cancer+normal vs

(cancer+normal vs 5

cancer+normal) cancer+normal)

(cancer vs cancer)

22- (normal vs normal) cgl521173

cg27598806 (cancer+normal vs 7-97935756

24119331 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

3- (normal vs normal) cgl059249

cgl 1423909 (cancer+normal vs 7-97935764

126010451 (cancer+normal vs

4

cancer+normal) cancer+normal)

3- cgl014553

cgl 1761535 (cancer vs cancer) 8-20350779

149051031 (normal vs normal)

3

(cancer vs cancer)

3- (cancer vs cancer) cgl725378

cgl l011913 8-67587258

149051159 (normal vs normal)

(cancer+normal vs 5

cancer+normal)

(cancer vs cancer)

3- cg0252063

cgl3050884 (cancer+normal vs 8-82021210

171976122 (normal vs normal)

9

cancer+normal)

(cancer vs cancer)

3- cg0106833

cgl6301768 (cancer+normal vs 8-82784211

183894727 (normal vs normal)

2

cancer+normal)

3- _C gl444360

cgl4533390 (cancer vs cancer) 9-40536407

65342843 (normal vs normal)

6

(cancer vs cancer)

4- THCA (cancer vs

cgl9850370 (cancer+normal vs

72205104 cancer)

cancer+normal)

(cancer vs cancer)

4- (cancer vs cancer)

cg27000934

87993109 Status - Hyper

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

5- 1- cgl208088

cg01885839 (cancer+normal vs (cancer vs cancer)

111017556 109634248 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- 1- cg0644096

cg20547724 (cancer+normal vs

131607888 (cancer+normal vs

155828926 0

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

cg0596018

5-1337747 (normal vs normal) cgl0641823 (cancer+normal vs 1-16160360

2 (cancer+normal vs cancer+normal)

cancer+normal) (cancer vs cancer)

5- 1- cgl963220

cg07033790 (cancer vs cancer) (cancer+normal vs

135479136 190446756 6

cancer+normal)

(cancer vs cancer)

5- 1- cgOO 14664

cg26547816 (cancer+normal vs (cancer vs cancer)

142527658 228644750 5

cancer+normal)

(cancer vs cancer)

5- cgl207217

cg07320595 (cancer vs cancer) 1-7830855 (cancer+normal vs

156485233 8

cancer+normal)

10- cgl954885

5-7873542 cgl5108958 (cancer vs cancer) (cancer vs cancer)

11239482 9

(normal vs normal)

(cancer vs cancer)

6- (cancer vs cancer) cgl368783

cg25545503 10-3514783 (cancer+normal vs

160680162 (cancer+normal vs 4

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- (cancer vs cancer) cgl253099

cgl5600935 10-5136782 (cancer+normal vs

101556684 (cancer+normal vs 4

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- 11- cg0181307 (normal vs normal) cg02307880 (cancer+normal vs

101566857 102401616 1 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cg2695413

7-1120141 cg02112681 (cancer+normal vs (cancer+normal vs

118437129 8

cancer+normal) cancer+normal)

(cancer vs cancer)

11- cg2087405

7-1141341 cg07242429 (cancer vs cancer) (cancer+normal vs

118437133 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cgOl 19527

7-1142433 cg00364696 (cancer+normal vs (cancer+normal vs

121567477 6

cancer+normal) cancer+normal)

(cancer vs cancer)

11- cg2291186

7-2679148 cg22788953 (cancer vs cancer) (cancer+normal vs

126173548 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cgl676388

7-2679726 cg22239213 (cancer+normal vs (cancer+normal vs

131941989 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cg2690621

7-2679971 cgl6184737 (cancer+normal vs (cancer+normal vs

17251956 7

cancer+normal) cancer+normal) cg0801788

7-4786364 cg01808969 (cancer vs cancer) 11-407180 (cancer vs cancer)

0

(cancer vs cancer) (cancer vs cancer)

8- 11- cgl535511

cg02225988 (cancer+normal vs (cancer+normal vs

141147612 45433358 1

cancer+normal) cancer+normal)

(cancer vs cancer)

8- 11- cg2725827

cg22504031 (cancer vs cancer) (cancer+normal vs

141147661 57424773 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- (cancer vs cancer) 11- cg0603820 (normal vs normal) cgl7018549

141147681 (cancer+normal vs 65487505 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 11- cg0307560

cgl8818267 (cancer+normal vs (cancer+normal vs

142311072 96123810 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 12- cg0573112

cgl9598713 (cancer+normal vs (cancer+normal vs

144601734 48100286 2

cancer+normal) cancer+normal)

8- (cancer vs cancer) 12- cgl807730

cg09580859 (cancer vs cancer)

144601800 (cancer+normal vs 51818049 4 cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 12- cgl304257

cg25900150 (cancer+normal vs (cancer+normal vs

144601851 65066768 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 12- cg2021787

cg00783706 (cancer+normal vs (cancer+normal vs

144601883 78224480 2

cancer+normal) cancer+normal)

(cancer vs cancer)

8- 12- cgl 108471

cg02723975 (cancer+normal vs (cancer vs cancer)

30209371 93834066 8

cancer+normal)

(cancer vs cancer)

8- 13- cg0558594 (normal vs normal) cg24296569 (cancer vs cancer)

30209386 20699452 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- (cancer vs cancer) 13- cg0221535

cgl4895559 (cancer+normal vs

30209391 (cancer+normal vs 53191046 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 13- cgl779928

cg26266308 (cancer+normal vs (cancer+normal vs

66701194 92001764 7

cancer+normal) cancer+normal)

(cancer vs cancer)

13- cg0764180

9-4541807 cgl3599596 (cancer vs cancer) (cancer+normal vs

92001959 7

cancer+normal)

(cancer vs cancer)

(cancer+normal vs 14- cgl034823

(cancer+normal vs cancer+normal) 31698967 4

cancer+normal)

(cancer vs cancer)

14- cgl843779

Status - Hyper (cancer+normal vs

31699236 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 14- cgl959042

cg08911820 (cancer+normal vs

110026001 (cancer+normal vs 51327604 1

cancer+normal) cancer+normal)

1- (cancer+normal vs 14- cg2731231 (cancer vs cancer) cg22815214

201083145 cancer+normal) 56046001 2 (normal vs normal)

1- (cancer+normal vs 15- cgl316025

cg03315764 (cancer vs cancer)

29448425 cancer+normal) 56286575 1

(cancer vs cancer)

(cancer vs cancer)

1- 15- cg0020065 (normal vs normal) cg00868131 (cancer+normal vs

54952901 60883225 3 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg0085203

cg21850722 (cancer+normal vs 16-2058572 (cancer+normal vs

64558474 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 17- cg2243459

cg24085039 (cancer+normal vs (cancer+normal vs

134211908 47072339 4

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer+normal vs 17- cg0620473

cg07121693 (cancer+normal vs

44148437 cancer+normal) 48785992 0

cancer+normal)

(cancer vs cancer)

11- (cancer+normal vs 17- cg2516112

cg07026904 (cancer+normal vs

114832606 cancer+normal) 66452343 9

cancer+normal)

(cancer vs cancer)

11- (cancer+normal vs 17- cg2416645

cg27471192 (cancer+normal vs

59015338 cancer+normal) 74248466 0

cancer+normal)

(cancer vs cancer)

11- (cancer+normal vs 19- cg2737786

cg01717649 (cancer+normal vs

66821665 cancer+normal) 16189693 3

cancer+normal)

12- cg03800721 (cancer vs cancer) 2-16790314 cgl948284 (cancer vs cancer) 120525338 (cancer vs cancer) 2 (cancer+normal vs

(normal vs normal) cancer+normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) 2- cg2043417

cg25969992

121088408 (cancer vs cancer)

(cancer+normal vs 172968684 8

cancer+normal)

12- (cancer vs cancer)

(cancer+normal vs 2- cg2138289

cgl9322788 (cancer+normal vs 125831167 cancer+normal) 178104794 0

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer)

(cancer vs cancer) 2- cg0353203

cgl9495013

52214119 (cancer+normal vs

(cancer+normal vs 242824433 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- (cancer vs cancer) cgl 138032

cg07375978 (normal vs nonnal)

2-24715213

52214320 (cancer+normal vs 7 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cgl903948

cg05238741 (cancer+normal vs 2-394115 (cancer+normal vs

52214758 1

cancer+normal) cancer+normal)

12- (cancer vs cancer)

(cancer+normal vs cg2151335

cg03998264 2-85553841 (cancer+normal vs

53932355 cancer+normal) 2

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer)

(cancer vs cancer) 20- cg2682789

cgl2232783

54422127 (cancer+normal vs

(cancer+normal vs 21105829 3

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- (normal vs normal) 21- cg0317357

cg04576672

54422239 (cancer+normal vs

(cancer+normal vs 33031392 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- (cancer vs cancer) 21- cg27441225 cg2639059 (normal vs normal)

54422350 (cancer+normal vs 41032396 8 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- (cancer vs cancer) 22- cg2733835

cg22378817 (normal vs nonnal)

54422488 (cancer+normal vs 46471129 3 (cancer+nonnal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- (cancer vs cancer) 22- cg0367795

cgl6983211

54427636 (cancer+normal vs

(cancer+normal vs 50524541 2

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) 3- cg2537591

cgl5700739

54427700 (cancer vs cancer)

(cancer+normal vs 155570275 6

cancer+normal)

(cancer vs cancer)

12- J- (cancer vs cancer) cg0505820

cg03416628 (cancer+normal vs

54446505 (cancer+nonnal vs

173129681 4

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- 3- cg0146517

cg08712054 (normal vs nonnal)

(cancer+normal vs

54446576 182208536 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cgl327981

cg03782861 ancer+normal vs 3-24725365

97857511 (c (cancer+normal vs

1

cancer+normal) cancer+normal)

13- (cancer vs cancer) cgl 944460

cgO 1866427 (cancer vs cancer)

3-44039204

113598068 (cancer vs cancer) 9 (normal vs normal) (cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- (cancer vs cancer) cg0728930 (normal vs normal) cg02223067 3-44039357

113623233 (cancer+normal vs 6 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) cg0185652 (cancer vs cancer) cgl6737670 3-44039509

113623300 (cancer+normal vs 5 (normal vs normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- cg0388954 (cancer vs cancer) cgOO 127894 (normal vs normal) 3-44039578

113623639 2 (normal vs normal)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- (cancer vs cancer) cgl012851

cgl5179805 3-98452940 (cancer+normal vs

113623659 (cancer+normal vs 1

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

13- cg0739064

cg09678836 (normal vs normal) 3-98453086 (cancer+normal vs

113623844 7

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer+normal vs 4- cg0336468

cg26168772 (cancer+normal vs

52739256 cancer+normal) 169402298 3

cancer+normal)

15- (cancer+normal vs 4- cg2396593 (cancer vs cancer) cg00200755

88945783 cancer+normal) 184828386 1 (normal vs normal)

(cancer vs cancer)

15- (cancer+normal vs 4- cg0627784 (normal vs normal) cgl2306333

97312064 cancer+normal) 186316674 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

15- (cancer+normal vs cg2487751

cg25271525 4-78742376 (cancer+normal vs

97316699 cancer+normal) 0

cancer+normal)

(cancer vs cancer)

16- (cancer+normal vs 5- cgl751928 (normal vs normal) cg08284233

20370531 cancer+normal) 115175001 0 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- 5- cg0719530 (normal vs normal) cg05090106 (cancer+normal vs

18908220 121648993 1 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- (cancer vs cancer) 5- cg0599815 (normal vs normal) cgl4807365

18908235 (cancer+normal vs 134075279 3 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) cg0123035

cg22220165 5-54527190 (cancer+normal vs

18908242 (cancer+normal vs 5

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) cgl961396

cgl6293732 5-83677872 (cancer+normal vs

35289543 (cancer+normal vs 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 6- cg2735336

cg05279092 (cancer+normal vs (cancer+normal vs

35290458 108145420 1

cancer+normal) cancer+normal)

17- (cancer vs cancer) 6- cg2765962 (cancer vs cancer) cgl9502920

35290635 (cancer+normal vs 108145539 2 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer)

6- cg0936514

cg07103093

35297752 (cancer+normal vs (cancer+normal vs

111738477 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- (normal vs normal) 6- cg2544114

cg04588165 (normal vs normal)

35300874 (cancer+normal vs 113012601 1 (cancer+normal vs cancer+normal) cancer+normal)

17- (cancer+normal vs cg0780156

cg00846995

46702028 6-31707151 (cancer vs cancer) cancer+normal) 9

(cancer vs cancer)

17- (cancer vs cancer) cg0888081

cg24042517

46704410 (cancer+normal vs 6-7909642 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cgl599110

cgl0342722 (cancer+normal vs

55056066 6-88407390 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer)

(cancer vs cancer) 7- cg0140132

cg21068610

7790179 (cancer+normal vs

(cancer+normal vs 101457175 7

cancer+normal) cancer+normal)

18- (cancer vs cancer) cg21263710 (cancer+normal vs cg0435813

49865488 7-1572252 (cancer+normal vs cancer+normal) 1

cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer)

(cancer vs cancer) cg0527941

cgl8596381

11199917 7-1572327

(cancer+normal vs (cancer+normal vs

3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- (cancer vs cancer) cg2646843

cgl 9751789 (normal vs normal) 11199944 7-1572571

(cancer+normal vs 0 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cg0872536

cgl2013591

11199965 7-18329916 (cancer vs cancer)

(cancer+normal vs 6

cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer)

(normal vs normal)

cg26988138 cg2220323

2639424 7-68983823 (cancer+normal vs

(cancer+normal vs 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- (cancer vs cancer) cg2541800

cg00506866 (normal vs normal)

10263480 7-79780310

(cancer+normal vs 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cg0090720

cgl9516340

10263696 (cancer+normal vs 7-92461971 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- 8- cgO 1598144 cg0602334 (normal vs normal)

21856440 (cancer+normal vs

127568650 5 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

2- 8- cg0192399

cg08863459 (normal vs normal)

72372965 (cancer+normal vs

127568677 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer)

8- cg0329442

cg00486564

73151879 (cancer+normal vs (cancer+normal vs

127866047 4

cancer+normal) cancer+normal)

2- (cancer vs cancer)

(cancer+normal vs cg0000707

cgl 1775291

91930138 8-67342600

cancer+normal) (cancer+normal vs

6

cancer+normal)

22- cgl4742445 (cancer vs cancer) 8-72268832 cg2570068 (cancer vs cancer) 30195299 (cancer+normal vs 6

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (cancer vs cancer) cgl878828

cg00589251 8-731697

132036382 (cancer+normal vs

(cancer+normal vs 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- (cancer vs cancer) cg0330108 (normal vs normal) cgl5903185 8-80679314

111530471 (cancer+normal vs 4 (cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

4- cg0753833 (normal vs normal) cg01612366 (cancer+normal vs 8-93107298

14113465 9 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

4- (cancer+normal vs 9- cgl356372

cgl9084053

189548707 (cancer+normal vs

cancer+normal) 101019042 8

cancer+normal)

(cancer vs cancer)

4- (cancer+normal vs cgl401473

cgl4500801 9-19378679

49204696 (cancer+normal vs

cancer+normal) 1

cancer+normal)

(cancer vs cancer)

5- (cancer+normal vs cgl359620

cgl8105361 9-35603605

135536668 (cancer+normal vs

cancer+normal) 8

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

cg0250171

5-1406177 (normal vs normal) cg24756227 (cancer+normal vs 9-89560185

4 (cancer+normal vs cancer+normal)

cancer+normal)

5- (cancer+normal vs

cg08754067

40833236 Status - Hypo

cancer+normal)

(normal vs normal)

(cancer vs cancer)

cg2691938 (cancer vs cancer)

5-475085 cgl5084390 (cancer+normal vs 1-10676290

7 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

(cancer vs cancer)

1- cg2323287 (cancer vs cancer)

5-475205 cg21743597 (cancer+normal vs

113819171 3 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

5- 1- cgl710701

cg02632185 (normal vs normal)

66299786 (cancer+normal vs

116925613 7

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- (cancer vs cancer) 1- cgl401409

cgl8118497

66299875 (cancer+normal vs

(cancer+normal vs 143663862 8

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

5- 1- cg2239533

cgl7449851 (normal vs normal)

66300406 (cancer+normal vs

147851370 5

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

5- 1- cg0882318

cgl 1831286 (normal vs normal)

66300433 (cancer+normal vs

153514482 2

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal) (cancer vs cancer)

5- 1- cg0811362 (cancer vs cancer) cg27116842 (normal vs normal)

66300503 182570870 8 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal) 6- (cancer vs cancer)

(cancer+normal vs 1- cgl324598

cgl0661263

167508170 (cancer+normal vs cancer+normal) 206765088 3

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cg01269795 cg2069894

26440101 (cancer+normal vs 1-51910707 (cancer+normal vs

2

cancer+normal) cancer+normal)

6- (cancer vs cancer)

(cancer+normal vs cgl790294

cg24146125

30690376 1-57040807 (cancer+normal vs cancer+normal) 7

cancer+normal)

(normal vs normal)

6- (cancer+normal vs cgl822945

cg06677013 (cancer vs cancer)

84570388 1-58622038

cancer+normal) 7 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7-1288184 cg0663471

cgl6275882 (cancer+normal vs 1-8442507 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer)

7- (cancer vs cancer)

10- cg0394813

cgl9412964

151328093 (cancer+normal vs (cancer+normal vs

120804863 9

cancer+normal) cancer+normal)

(normal vs normal)

7-1687852 (cancer+normal vs 10- cgl696057

cg02412346 (cancer vs cancer) cancer+normal) 131200784 3 (cancer+normal vs cancer+normal)

(cancer vs cancer)

10-

7-1708823 cg2632829

cgl7202717 (normal vs normal)

(cancer+normal vs

131200802 1 (cancer vs cancer) cancer+normal)

(normal vs normal)

(normal vs normal)

7- 10- cgl 164214

cg25983901 (cancer vs cancer)

46972700 (cancer+normal vs

134559553 0

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer) (normal vs normal)

7- (cancer vs cancer) 10- cgl775094

cg08986767 (cancer vs cancer)

92747308 (cancer+normal vs 134559637 6 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

8- (cancer vs cancer) 10- cg07554329 cg0792795 (cancer vs cancer)

107669778 (cancer+normal vs 134559696 3 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

8- (cancer vs cancer) 10- cgl705478

cgl7136799 (cancer vs cancer)

107669783 (cancer+normal vs 134559939 3 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 10- cgl244971

cg26622232

107669787 (cancer vs cancer)

(cancer+normal vs 134561116 6

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer)

(cancer vs cancer) cg0433690

cgl7176732

107669856 10-412257 (cancer+normal vs

(cancer+normal vs 5

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

8- (cancer vs cancer) 11- cgl013183

cgl7212289 (cancer vs cancer)

107669906 (cancer+normal vs 111167086 6 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

8- (cancer vs cancer) 11- cgl542752

cgl6326979 (cancer vs cancer)

107670161 (cancer+normal vs 35252384 0 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer)

11- cgl899707

cg00298796

107670358 (cancer+normal vs (cancer+normal vs

57105500 5

cancer+normal) cancer+normal) (cancer vs cancer) (normal vs normal)

8- (cancer vs cancer) 11- cg2463051 (cancer vs cancer) cgl3242160

55294610 (cancer+normal vs 75852389 6 (cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

8- (cancer vs cancer) 11- cgl923441 (cancer vs cancer) cg07664990

55294721 (cancer+normal vs 78638670 2 (cancer+normal vs

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

8- 12- cg2271494 (cancer vs cancer) cg25766247 (cancer+normal vs

59714165 109911508 2 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- cg0295291

8-9760528 cg00528902 (cancer+normal vs (cancer+normal vs

120173011 8

cancer+normal) cancer+normal)

(cancer vs cancer)

9- (cancer+normal vs 12- cgl457824

cg21223423 (cancer+normal vs

136472927 cancer+normal) 120173057 7

cancer+normal)

(cancer vs cancer)

9- (cancer+normal vs 12- cgl733859

cg04961911 (cancer+normal vs

35079141 cancer+normal) 120173114 4

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 12- cgl517560

cgl3914324 (cancer+normal vs (cancer+normal vs

79320026 123636717 8

cancer+normal) cancer+normal)

12- cgl661659

Status - Hypo (cancer vs cancer)

16067423 9

(cancer vs cancer) (cancer vs cancer)

1- cg0384178

cg00902464 (cancer+normal vs 12-1890922 (cancer+normal vs

101094117 4

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

cgl313027 (cancer vs cancer)

1-2026193 cg22712840 (cancer+normal vs 12-3030602

4 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

1- (cancer vs cancer) 14- cg0181387

cgl0325088 (cancer+normal vs

217724849 (cancer+normal vs 103369717 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- cg2277976

1-2427655 cgl0219816 (cancer+normal vs (cancer+normal vs

103369786 5

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 14- cg0354864

cgl2081359 (cancer+normal vs (cancer vs cancer)

25069665 103369816 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- cgl831583

1-2996949 cg22506548 (cancer+normal vs (cancer+normal vs

64909119 4

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

15- cg0803628 (cancer vs cancer)

1-3162454 cgl2800122 (cancer+normal vs

40677854 9 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

1- 15- cg0404230

cgl5187606 (cancer+normal vs (cancer vs cancer)

47656853 55562773 5

cancer+normal)

(cancer vs cancer)

1- cg0969235

cgl7904129 (cancer+normal vs 16-1677047 (cancer vs cancer)

54195800 5

cancer+normal)

(cancer vs cancer)

1- cg0807978

cg27311970 (cancer+normal vs 16-2282372 (cancer vs cancer)

54195830 7

cancer+normal)

1- (cancer vs cancer) cg0392974 (normal vs normal) cg25011368 16-2282618

55317286 (cancer+normal vs 7 (cancer vs cancer) cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg0415276

cgl 1832870 (cancer+normal vs 16-2282957

81001617 (cancer+normal vs

7

cancer+normal) cancer+normal)

10- (cancer vs cancer)

(cancer+normal vs 16- cg0385641

cgl7141577

12940536 (cancer+normal vs cancer+normal) 23410986 1

cancer+normal)

(cancer vs cancer)

10- (cancer+normal vs cg0617042

cg02220418 16-4164087 (cancer+normal vs 130831421 cancer+normal) 5

cancer+normal)

(normal vs normal)

(normal vs normal)

10- cgl027804

cg07646467 (cancer vs cancer)

(cancer+normal vs 16-4802848

130844899 6 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs nomial)

11- (cancer+normal vs cgl675547

cg08160224 (cancer vs cancer)

16-4802990

62248459 cancer+normal) 5 (cancer+normal vs cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) (cancer vs cancer)

16- cg0688093

cg21039563

64323816 (cancer+normal vs

(cancer+normal vs 57147300 0

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cg0687134

cgl4400030 (cancer+normal vs 17-452707

122498111 (cancer+normal vs

4

cancer+normal) cancer+normal)

(normal vs nomial)

(cancer vs cancer)

12- 17- cgl228079

cg00230120 (cancer vs cancer)

(cancer+normal vs

1609346 48856029 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) 17- cg2422017

cg24859375

7121914 (cancer vs cancer)

(cancer+normal vs 80541649 8

cancer+normal)

(cancer vs cancer) (normal vs normal)

13- (cancer vs cancer)

cg21980364 cg2589995

18-8660164 (cancer vs cancer) 111880998 (cancer+normal vs 4 (cancer+normal vs cancer+normal) cancer+normal)

(normal vs nomial)

13- (cancer+normal vs cgl351341

cg01233786 (cancer vs cancer)

19-4676202

113498450 cancer+normal) 1 (cancer+normal vs cancer+normal)

(normal vs nomial)

(cancer vs cancer)

13- cgl832861

cg05508408 (cancer vs cancer)

(cancer+normal vs 19-4676623

114138019 2 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (normal vs normal)

13- (cancer vs cancer)

cg21238257 cg0685615 (cancer vs cancer)

2-11774852

114138260 (cancer+normal vs 5 (cancer+normal vs cancer+normal) cancer+normal)

13- vs 2- cg27591016 (cancer+normal cg2492392

47259150 (cancer vs cancer) cancer+normal) 193013929 0

(normal vs normal)

(cancer vs cancer)

13- 2- cg0958995

cg20278383 (cancer vs cancer)

96086098 (cancer vs cancer)

236897639 1

(cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

13- cg26557005 cg0002708

2-3325158 (cancer vs cancer) (cancer+normal vs

96086249 1 (cancer+normal vs cancer+normal)

cancer+normal) (normal vs normal)

13- (cancer+normal vs cg0469438 (cancer vs cancer) cg06155414 2-69857465

97893311 cancer+normal) 9 (cancer+normal vs cancer+normal)

(cancer vs cancer)

13- cgl690182

cgl 1862665 (cancer+normal vs 2-98409192 (cancer vs cancer)

97980712 1

cancer+normal)

14- (cancer+normal vs cg0248922

cgl9987354 2-98409290 (cancer vs cancer)

64357795 cancer+normal) 8

(cancer vs cancer)

14- cg2381211

cg02212698 (cancer+normal vs 2-98409368 (cancer vs cancer)

89628141 9

cancer+normal)

(cancer vs cancer)

14- cg0696947

cgl8518804 (cancer+normal vs 2-98409379 (cancer vs cancer)

91275103 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- 20- cgl789429

cg24180006 (cancer+normal vs (cancer+normal vs

99893325 32436418 3

cancer+normal) cancer+normal)

(cancer vs cancer)

16- 20- cg0631377

cg03245889 (cancer+normal vs (cancer vs cancer)

15127172 35399961 5

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

16- (cancer vs cancer) 20- cg0017116

cg06978461 (cancer+normal vs

15127193 (cancer+normal vs 35444275 6

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

16- 20- cg0681404 (cancer vs cancer) cg00879840 (cancer+normal vs

78323024 35444364 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

16- (cancer vs cancer) 20- cg0820918

cg03212183 (cancer+normal vs

81565917 (cancer+normal vs 35444560 4

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (cancer vs cancer) 22- cg2715705

cgl8449048 (cancer+normal vs

18854760 (cancer+normal vs 42563204 0

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- (cancer vs cancer) 22- cgl331812

cg25567048 (cancer+normal vs

18854799 (cancer+normal vs 45737514 9

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- (cancer vs cancer) 3- cg0039595

cg00306284 (cancer+normal vs

18855313 (cancer+normal vs 113413263 1

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- (cancer vs cancer) cg0213113

cg09632029 3-11597868 (cancer+normal vs

18855506 (cancer+normal vs 0

cancer+normal) cancer+normal)

(cancer vs cancer)

17- cg0066851

cg03950716 (cancer+normal vs 3-11597941 (cancer vs cancer)

40064155 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cg2139651

cg20818528 (cancer+normal vs 3-11655466 (cancer+normal vs

4510743 7

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 3- cg2731534

cg00349608 (cancer+normal vs (cancer vs cancer)

4520467 184042708 8

cancer+normal)

(cancer vs cancer) (normal vs normal)

17- 3- cg2593113

cg08137716 (cancer+normal vs (cancer vs cancer)

46871905 195709698 8

cancer+normal) (cancer+normal vs cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- cgl372301

cg09777416 (cancer vs cancer)

(cancer+normal vs 3-52737693

7225013 1 (cancer+normal vs cancer+normal)

cancer+normal)

(normal vs normal)

17- (cancer+normal vs 4- cg0797938

cgl2648893 (cancer vs cancer)

78305896 cancer+normal) 169573255 8 (cancer+normal vs cancer+normal)

(cancer vs cancer) (normal vs normal)

17- (cancer vs cancer) 4- cg0955714

cg06975080 (cancer vs cancer)

78700928 (cancer+normal vs 183816164 9 (cancer+normal vs cancer+normal) cancer+normal)

17- (cancer vs cancer)

(cancer+normal vs 4- cg0739682

cg25899969

78817938 ancer+normal vs cancer+normal) 184683218 (c

7

cancer+normal)

(normal vs normal)

(cancer vs cancer)

19- 4- cg0922753

cgl 1883009 (cancer vs cancer)

(cancer+normal vs

13198960 186945339 3

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

19- cgl l69218

cgl 1656553 (cancer+normal vs 4-2687547

1424658 (cancer vs cancer)

1

cancer+normal)

(normal vs normal)

19- (cancer+normal vs cgl 857976

cgl7759252 (cancer vs cancer)

4-83323585

18888081 cancer+normal) 1 (cancer+normal vs cancer+normal)

(normal vs normal)

(cancer vs cancer)

2- 5- cg01441308 cg0101811 (cancer vs cancer)

(cancer+normal vs

127811853 134814626 0

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer) (normal vs normal)

2- (cancer vs cancer) cg0664662

cg26015513 (cancer vs cancer)

5-78766902

201218948 (cancer+normal vs 2 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

2- 6- (cancer vs cancer) cg0198143

cg05148385 (cancer+normal vs

213950646 138200309 (cancer+normal vs

3

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer)

(cancer vs cancer) 6- cg0506650

cg09473180 (cancer+normal vs

217403190 (cancer+normal vs 169978311 3

cancer+normal) cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer)

6- cgl321183

cgl7963548 (cancer+normal vs

224824723 169978387 (cancer+normal vs

2

cancer+normal) cancer+normal)

2- (cancer vs cancer)

(cancer+normal vs 6- cg2537343

cgl5425670

42461109 cancer+normal) 170028109 (cancer+normal vs

8

cancer+normal)

(normal vs normal)

2- (cancer+normal vs cg2137679

cg00336220 (cancer vs cancer)

6-30094960

96940284 cancer+normal) 9 (cancer+normal vs cancer+normal)

(cancer vs cancer) (normal vs normal)

20- (cancer vs cancer) 7- cg0098297

cg21209310 (cancer vs cancer)

6025272 (cancer+normal vs 101522290 4 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

22- (cancer vs cancer)

7- cg0303281

cg27598806 (cancer+normal vs

24119331 134613526 (cancer+normal vs

6

cancer+normal) cancer+normal)

3- (cancer vs cancer)

cgl 1423909 cgl836538

7-33725819 (normal vs normal)

126010451 (cancer+normal vs 3 (cancer vs cancer) cancer+normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

3- (cancer vs cancer) cg2239955

cgl l011913 7-5529868

149051159 (cancer+normal vs

(cancer+normal vs 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- 8- cg0544577

cgl3050884 (cancer+normal vs

171976122 (cancer+normal vs

126202653 2

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

3- cg2551598 (cancer vs cancer) cgl6301768 (cancer+normal vs 8-12860315

183894727 2 (cancer+normal vs

cancer+normal)

cancer+normal)

3- (cancer+normal vs 9- cgl400362

cg22118297 (cancer vs cancer)

64547310 cancer+normal) 123204555 7

(cancer vs cancer)

3- (cancer+normal vs 9- cgl417728

cgl4187266

64547346 (cancer+normal vs

cancer+normal) 126153067 9

cancer+normal)

(normal vs normal)

(cancer+normal vs 9- cgl359555 (cancer vs cancer)

4-1844807 cgl6500874

cancer+normal) 129648322 6 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

4- (cancer+normal vs

cgl9850370 (cancer+normal vs

72205104 cancer+normal)

cancer+normal)

(cancer vs cancer)

4- (cancer vs cancer)

cg27000934

87993109 Status - Hyper

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer+normal vs 1- cg0644096

5-1100209 cg05978154 (cancer+normal vs

cancer+normal) 155828926 0

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- cg0596018 (normal vs normal) cg01885839 (cancer+normal vs 1-16160360

111017556 2 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

5- (normal vs normal)

1- cg0484620

cg20547724 (cancer+normal vs

131607888 (cancer+normal vs

167690438 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cgl963220

5-1337747 cgl0641823 (cancer+normal vs (cancer+normal vs

190446756 6

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer+normal vs cgl207217

5-1339114 cg20700235 1-7830855 (cancer+normal vs

cancer+normal) 8

cancer+normal)

(cancer vs cancer)

5- 10- cg0677790 (cancer+normal vs cg26547816 (cancer+normal vs

142527658 127622996 2 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer+normal vs cgl368783

5-1514511 cg00281273 10-3514783 (cancer+normal vs

cancer+normal) 4

cancer+normal)

(cancer vs cancer)

5- (cancer+normal vs cgl253099

cg24667575 10-5136782

172097064 (cancer+normal vs

cancer+normal) 4

cancer+normal)

(cancer vs cancer)

6- (cancer+normal vs 11- cg0181307 (normal vs normal) cg02666489

160680115 cancer+normal) 102401616 1 (cancer+normal vs

cancer+normal)

(normal vs normal) (cancer vs cancer)

6- 11- cg2695413

cg25545503 (cancer vs cancer)

160680162 (cancer+normal vs

118437129 8

(cancer+normal vs cancer+normal) cancer+normal)

6- (cancer vs cancer)

(cancer+normal vs

cg24249695 11- cg2087405

37896180 (cancer+normal vs cancer+normal) 118437133 2

cancer+normal)

(cancer vs cancer)

7- (cancer vs cancer) (cancer vs cancer) cgl5600935 11- cgOl 19527

101556684 (cancer+normal vs

(cancer+normal vs 121567477 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- cg02307880 11- cg2291186

(cancer+normal vs

101566857 (cancer+normal vs

126173548 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7-1120141 cg02112681 11- cgl676388

(cancer+normal vs (cancer+normal vs

131941989 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7-1142433 cg00364696 11- cg2690621

(cancer+normal vs (cancer+normal vs

17251956 7

cancer+normal) cancer+normal)

(normal vs normal)

(cancer+normal vs

7-2679546 cgl4893935 cgl428929

11-1974984 (cancer+normal vs cancer+normal) 4

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7-2679726 11- cg22239213 cgl535511

(cancer+normal vs (cancer+normal vs

45433358 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7-2679971 cgl6184737 11- cg2725827

(cancer+normal vs (cancer+normal vs

57424773 2

cancer+normal) cancer+normal)

(cancer vs cancer)

7- (cancer+normal vs

cg05425699 11- cg0603820 (normal vs normal)

47580148 cancer+normal) 65487505 1 (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 11- cg02225988 cg0307560

(cancer+normal vs

141147612 (cancer+normal vs

96123810 5

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- (cancer vs cancer)

cgl7018549 12- cg0573112

141147681 (cancer+normal vs

(cancer+normal vs 48100286 2

cancer+normal) cancer+normal)

8- (cancer vs cancer)

(cancer+normal vs

cgl2865888 12- cgl 304257

141220177 (cancer+normal vs cancer+normal) 65066768 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 12- cgl8818267 cg2021787

(cancer+normal vs

142311072 (cancer+normal vs

78224480 2

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- 13- cgl9598713 cg0558594 (normal vs normal)

(cancer+normal vs

144601734 20699452 7

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 13- cg09580859 cg0221535

(cancer+normal vs

144601800 (cancer+normal vs

53191046 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 13- cg25900150 cgl779928

(cancer+normal vs

144601851 (cancer+normal vs

92001764 7

cancer+normal) cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer)

13- cg00783706 cg0764180

(cancer+normal vs

144601883 (cancer+normal vs

92001959 7

cancer+normal) cancer+normal)

(cancer vs cancer)

8- 14- cg0677016

cg02723975 (cancer+normal vs

(cancer+normal vs

30209371 102094618 3 cancer+normal) cancer+normal)

8- (cancer vs cancer) 14- cg2607611

cgl4895559 (cancer+normal vs

30209391 (cancer vs cancer) 104666047 9 cancer+normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 14- cgl034823

cg26266308 (cancer+normal vs (cancer+normal vs

66701194 31698967 4

cancer+normal) cancer+normal)

(cancer vs cancer)

14- cgl843779

(normal vs normal) (cancer+normal vs

31699236 2

cancer+normal)

(cancer vs cancer)

14- cgl959042

Status - Hyper (cancer+normal vs

51327604 1

cancer+normal)

(cancer vs cancer)

1- 15- cg0020065 (normal vs normal) cg25200152 (normal vs normal)

147790458 60883225 3 (cancer+normal vs cancer+normal)

(cancer vs cancer)

1- cg0085203

cg26561681 (normal vs normal) 16-2058572 (cancer+normal vs

21376633 3

cancer+normal)

(cancer vs cancer)

1- 17- cg2243459

cgl3936452 (normal vs normal) (cancer+normal vs

47911336 47072339 4

cancer+normal)

(cancer vs cancer)

1- 17- cg0620473

cg06531379 (normal vs normal) (cancer+normal vs

47911449 48785992 0

cancer+normal)

(cancer vs cancer)

1- 17- cg2516112

cg26864230 (normal vs normal) (cancer+normal vs

47911508 66452343 9

cancer+normal)

(cancer vs cancer)

1- 17- cg2416645

cg21535606 (normal vs normal) (cancer+normal vs

47911940 74248466 0

cancer+normal)

18- cg2052833 (cancer+normal vs

1-6507693 cg05068146 (normal vs normal)

21976748 8 cancer+normal)

19- cg2649583 (cancer+normal vs

1-6507804 cg23919534 (normal vs normal)

11484842 9 cancer+normal)

(cancer vs cancer)

10- 19- cg2737786

cgl8279326 (normal vs normal) (cancer+normal vs

102475324 16189693 3

cancer+normal)

(cancer vs cancer)

10- cgl948284

cg26156687 (normal vs normal) 2-16790314 (cancer+normal vs

102586168 2

cancer+normal)

(cancer vs cancer)

10- 2- cg2138289

cg07046369 (normal vs normal) (cancer+normal vs

102586254 178104794 0

cancer+normal)

(cancer vs cancer)

10- 2- cg0353203

cg02770534 (normal vs normal) (cancer+normal vs

102586454 242824433 0

cancer+normal)

(cancer vs cancer)

10- cgl 138032 (normal vs normal) cg26439963 (normal vs normal) 2-24715213

102587110 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

10- cgl903948

cg04943368 (normal vs normal) 2-394115 (cancer+normal vs

102587322 1

cancer+normal)

10- cg2340487 (cancer+normal vs cg23206032 (normal vs normal) 2-85553759

102587844 7 cancer+normal)

(cancer vs cancer)

10- cg2151335

cgl6574134 (normal vs normal) 2-85553841 (cancer+normal vs

102588315 2

cancer+normal)

10- (cancer vs cancer) 20- cg0207146 (cancer+normal vs cg20095124

102588691 (normal vs normal) 10200617 3 cancer+normal)

10- cgl7480467 (cancer vs cancer) 20- cg2682789 (cancer vs cancer) 102588959 (cancer vs cancer) 21105829 3 (cancer+normal vs

(normal vs normal) cancer+normal) (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

10- 21- cg0317357

cgl4778235 (normal vs normal) (cancer+normal vs

102589102 33031392 0

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

10- 21- cg2639059 (normal vs normal) cg08217716 (normal vs normal)

102589250 41032396 8 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

10- 22- cg2733835 (normal vs normal) cg06921011 (normal vs normal)

102589467 46471129 3 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

10- 22- cg0367795

cgl8494190 (normal vs normal) (cancer+normal vs

102589532 50524541 2

cancer+normal)

(cancer vs cancer)

10- 3- cg0505820

cg04436818 (normal vs normal) (cancer+normal vs

102589545 173129681 4

cancer+normal)

(cancer vs cancer)

10- 3- cg0146517 (normal vs normal) cg08823110 (normal vs normal)

102589840 182208536 7 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

10- cgl327981

cg06379721 (normal vs normal) 3-24725365 (cancer+normal vs

102590401 1

cancer+normal)

(cancer vs cancer)

10- _C gl944460 (normal vs normal) cgl0684486 (normal vs normal) 3-44039204

12917286 9 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

10- cg0728930 (normal vs normal) cg25104555 (normal vs normal) 3-44039357

16562998 6 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- (normal vs normal) cgl012851

cg26063719 3-98452940 (cancer+normal vs

17273187 (cancer+normal vs 1

cancer+normal) cancer+normal)

(cancer vs cancer)

11- cg0739064

cg05451852 (normal vs normal) 3-98453086 (cancer+normal vs

123300839 7

cancer+normal)

(cancer vs cancer)

11- 4- cg0336468

cgl4917395 (normal vs normal) (cancer+normal vs

123300849 169402298 3

cancer+normal)

11- 4- cg0121406 (cancer+normal vs cgl9419279 (normal vs normal)

123300867 174290520 1 cancer+normal)

(cancer vs cancer)

11- 4- cg0627784 (normal vs normal) cg03401096 (normal vs normal)

123301171 186316674 9 (cancer+normal vs

cancer+normal)

11- cg0702707 (cancer+normal vs cgl0904699 (normal vs normal) 4-39461721

123301490 5 cancer+normal)

(cancer vs cancer)

11- cg2487751

cg05289253 (normal vs normal) 4-78742376 (cancer+normal vs

123301674 0

cancer+normal)

11- cgl4085017 (normal vs normal) 5- cgl751928 (cancer vs cancer) 63775226 115175001 0 (normal vs normal)

(cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

12- 5- cg0719530 (normal vs normal) cg08752459 (normal vs normal)

10022682 121648993 1 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

12- 5- cg0599815 (normal vs normal) cgl2591315 (normal vs normal)

10022688 134075279 3 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (normal vs normal)

12- cgl469765

cg03800721 (normal vs normal) 5-42858327 (cancer+normal vs

120525338 7

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

12- cg0123035

cg03132556 (normal vs normal) 5-54527190 (cancer+normal vs

54366760 5

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- (normal vs normal) cgl961396

cg04576672 5-83677872 (cancer+normal vs

54422239 (cancer+normal vs 8

cancer+normal) cancer+normal)

(cancer vs cancer)

12- 6- cg2735336

cgl8695839 (normal vs normal) (cancer+normal vs

54446944 108145420 1

cancer+normal)

(cancer vs cancer)

12- 6- cg2765962

cg03923561 (normal vs normal) (cancer+normal vs

54447220 108145539 2

cancer+normal)

(cancer vs cancer)

12- 6- cg0936514

cg09720701 (normal vs normal) (cancer+normal vs

54447283 111738477 7

cancer+normal)

(cancer vs cancer)

12- 6- cg2544114 (normal vs normal) cgl5233062 (normal vs normal)

54447349 113012601 1 (cancer+normal vs

cancer+normal)

(normal vs normal)

12- 6- cgl322145

cgl 1585893 (normal vs normal) (cancer+normal vs

54447430 160112632 8

cancer+normal)

(cancer vs cancer)

12- cg0888081

cg07266404 (normal vs normal) 6-7909642 (cancer+normal vs

54447584 7

cancer+normal)

(cancer vs cancer)

12- cgl599110

cg22747076 (normal vs normal) 6-88407390 (cancer+normal vs

54447873 4

cancer+normal)

(cancer vs cancer)

12- 7- cg0140132

cgl 1746813 (normal vs normal) (cancer+normal vs

54448090 101457175 7

cancer+normal)

12- 7- cg0784710 (cancer+normal vs cg02716635 (normal vs normal)

97857304 150785000 1 cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

13- cg0435813

cgOO 127894 (normal vs normal) 7-1572252 (cancer+normal vs

113623639 1

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- (cancer vs cancer) cg0527941

cg09678836 7-1572327 (cancer+normal vs

113623844 (normal vs normal) 3

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

15- cg2646843 (normal vs normal) cgl2180319 (normal vs normal) 7-1572571

48705662 0 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer) cg2220323

cg24340572 7-68983823 (cancer+normal vs

69887053 (normal vs normal) 7

cancer+normal)

(cancer vs cancer)

17- cg2541800 (normal vs normal) cg04636269 (normal vs normal) 7-79780310

35300868 1 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- (normal vs normal) cg0090720

cg04588165 7-92461971 (cancer+normal vs

35300874 (cancer+normal vs 4

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 8- cg0602334 (normal vs normal) cgl2656291 (normal vs normal)

35302352 127568650 5 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

17- 8- cg0192399 (normal vs normal) cg04264908 (normal vs normal)

35303330 127568677 9 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

17- 8- cg0329442

cgl4240300 (normal vs normal) (cancer+normal vs

46705018 127866047 4

cancer+normal)

17- cg0403572 (cancer+normal vs cg20710730 (normal vs normal) 8-27323467

46705577 8 cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

19- (normal vs normal) cg0000707

cg26988138 8-67342600 (cancer+normal vs

2639424 (cancer+normal vs 6

cancer+normal) cancer+normal)

(cancer vs cancer)

2- cgl878828

cg27494897 (normal vs normal) 8-731697 (cancer+normal vs

151061125 4

cancer+normal)

(cancer vs cancer)

2- cg0330108 (normal vs normal) cg23244226 (normal vs normal) 8-80679314

161901182 4 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

2- cg0753833 (normal vs normal) cg08474164 (normal vs normal) 8-93107298

177503596 9 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

2- 9- cgl356372

cgl0612128 (normal vs normal) (cancer+normal vs

220942540 101019042 8

cancer+normal)

2- 9- cg2404647 (cancer+normal vs cg25996077 (normal vs normal)

228331319 130212550 4 cancer+normal)

(cancer vs cancer)

2- cgl401473

cg21019043 (normal vs normal) 9-19378679 (cancer+normal vs

237080535 1

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl359620

cgl6781647 9-35603605 (cancer+normal vs

73151595 (normal vs normal) 8

cancer+normal)

(cancer vs cancer)

3- cg0250171 (normal vs normal) cgl3696490 (normal vs normal) 9-89560185

151488006 4 (cancer+normal vs

cancer+normal)

3- cgl 1931463 (normal vs normal)

156807379 Status - Hypo (normal vs normal)

4- cg2691938 (cancer vs cancer) cg23206160 (normal vs normal) 1-10676290

140661865 7 (cancer+normal vs

cancer+normal)

4- cg0483012 (cancer+normal vs cgl8777299 (normal vs normal) 1-10720111

26994740 4 cancer+normal)

(normal vs normal)

5- 1- cg2323287 (cancer vs cancer) cgl8301423 (normal vs normal)

131593218 113819171 3 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

1- cgl710701

5-472564 cg00049323 (normal vs normal) (cancer+normal vs

116925613 7

cancer+normal)

(cancer vs cancer)

5- 1- cgl401409

cgl7633020 (normal vs normal) (cancer+normal vs

58335180 143663862 8

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) 1- cg2239533

cgl8242030 (cancer+normal vs

58335271 (normal vs normal) 147851370 5

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) 1- cg0882318

cg22078451 (cancer+normal vs

58335681 (normal vs normal) 153514482 2

cancer+normal)

(cancer vs cancer)

(normal vs normal) (cancer vs cancer)

5- 1- cg0811362 (cancer vs cancer) cg02632185 (normal vs normal)

66299786 182570870 8 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

5- 1- cgl324598

cgl7449851 (normal vs normal) (cancer+normal vs

66300406 206765088 3

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

5- cg2069894

cgl 1831286 (normal vs normal) 1-51910707 (cancer+normal vs

66300433 2

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

5- cgl790294

cg27116842 (normal vs normal) 1-57040807 (cancer+normal vs

66300503 7

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

5- cgl822945 (cancer vs cancer) cg22120063 (normal vs normal) 1-58622038

72596188 7 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

5- cg0663471

cg09553242 (normal vs normal) 1-8442507 (cancer+normal vs

72597015 7

cancer+normal)

(cancer vs cancer)

5- 10- cg0394813

cgl8595065 (normal vs normal) (cancer+normal vs

72597126 120804863 9

cancer+normal)

(normal vs normal)

5- 10- cgl659605

cg09835740 (normal vs normal) (cancer+normal vs

72597231 121271746 2

cancer+normal)

(normal vs normal)

5- 10- cgl696057 (cancer vs cancer) cgl6667631 (normal vs normal)

72597316 131200784 3 (cancer+normal vs

cancer+normal)

5- 10- cgl 164214 (normal vs normal) cg04221521 (normal vs normal)

72597715 134559553 0 (cancer vs cancer) (cancer+normal vs

cancer+normal)

(normal vs normal)

5- (cancer vs cancer) 10- cgl775094 (cancer vs cancer) cg25113089

72598192 (normal vs normal) 134559637 6 (cancer+normal vs

cancer+normal)

(normal vs normal)

5- 10- cg0792795 (cancer vs cancer) cg00766220 (normal vs normal)

72598865 134559696 3 (cancer+normal vs

cancer+normal)

(normal vs normal)

5- 10- cgl705478 (cancer vs cancer) cgl 1795854 (normal vs normal)

72598965 134559939 3 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

5- cg0433690

cg00462107 (normal vs normal) 10-412257 (cancer+normal vs

72677230

cancer+normal)

(normal vs normal)

5- 11- cgl013183 (cancer vs cancer) cgO 1927745 (normal vs normal)

72677723 111167086 6 (cancer+normal vs

cancer+normal)

(normal vs normal)

6- 11- cgl542752 (cancer vs cancer) cg01302136 (normal vs normal)

43118059 35252384 0 (cancer+normal vs

cancer+normal)

(normal vs normal)

6- cg0245334

cg04110902 (normal vs normal) 11-3638458 (cancer+normal vs

45500999 8

cancer+normal)

(cancer vs cancer)

6- 11- cgl899707

cgl2976463 (normal vs normal) (cancer+normal vs

50488809 57105500 5

cancer+normal)

(normal vs normal)

7- (cancer vs cancer) 11- cg0778318

cg07039423 (cancer+normal vs

128531106 (normal vs normal) 75852355 3

cancer+normal)

(normal vs normal)

11- cg2463051 (cancer vs cancer)

7-1286023 cg07296447 (normal vs normal)

75852389 6 (cancer+normal vs

cancer+normal)

(normal vs normal)

7- 11- cgl923441 (cancer vs cancer) cg25884711 (normal vs normal)

24323840 78638670 2 (cancer+normal vs

cancer+normal)

(normal vs normal)

(normal vs normal)

7- 12- cg2271494 (cancer vs cancer) cg25983901 (cancer+normal vs

46972700 109911508 2 (cancer+normal vs

cancer+normal)

cancer+normal)

(cancer vs cancer)

8- 12- cg0295291

cg06033789 (normal vs normal) (cancer+normal vs

105899330 120173011 8

cancer+normal)

(cancer vs cancer)

8- 12- cgl457824

cgl2116192 (normal vs normal) (cancer+normal vs

27730485 120173057 7

cancer+normal)

(cancer vs cancer)

12- cgl733859

Status - Hypo (cancer+normal vs

120173114 4

cancer+normal)

(cancer vs cancer)

1- 12- cgl517560

cg09168939 (normal vs normal) (cancer+normal vs

164652019 123636717 8

cancer+normal)

(cancer vs cancer)

1- cg0384178

cgl4095720 (normal vs normal) 12-1890922 (cancer+normal vs

201195051

cancer+normal) (normal vs normal)

1- cgl313027 (cancer vs cancer) cgl0985956 (normal vs normal) 12-3030602

87774698 4 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

10- 14- cg0181387

cg22605290 (normal vs normal) (cancer+normal vs

130757223 103369717 7

cancer+normal)

(cancer vs cancer)

10- 14- cg2277976

cgl6621196 (normal vs normal) (cancer+normal vs

130757242 103369786 5

cancer+normal)

(cancer vs cancer)

10- 14- cgl831583

cgl4701597 (normal vs normal) (cancer+normal vs

130757617 64909119 4

cancer+normal)

10- 14- cg0935049 (cancer+normal vs cg24098131 (normal vs normal)

130844121 68214742 7 cancer+normal)

(normal vs normal)

10- 15- cg0803628 (cancer vs cancer) cgl3303464 (normal vs normal)

130844209 40677854 9 (cancer+normal vs

cancer+normal)

10- 15- cg2641054 (cancer+normal vs cgl9825759 (normal vs normal)

130844321 45900639 0 cancer+normal)

10- 15- cg0735389 (cancer+normal vs cgl5030949 (normal vs normal)

130844727 90611758 5 cancer+normal)

(normal vs normal)

10- cg0392974 (cancer vs cancer) cgl0652915 (normal vs normal) 16-2282618

130844860 7 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

10- cg0415276

cg27596297 (normal vs normal) 16-2282957 (cancer+normal vs

130844884 7

cancer+normal)

(normal vs normal) (cancer vs cancer)

10- 16- cg0385641

cg07646467 (cancer+normal vs (cancer+normal vs

130844899 23410986 1

cancer+normal) cancer+normal)

10- 16- cg2737201 (cancer+normal vs cg03625662 (normal vs normal)

132891319 27526259 5 cancer+normal)

(cancer vs cancer)

10- cg0617042

cgl0589396 (normal vs normal) 16-4164087 (cancer+normal vs

132891341 5

cancer+normal)

(normal vs normal)

10- cgl027804 (cancer vs cancer) cgl5167871 (normal vs normal) 16-4802848

132891371 6 (cancer+normal vs

cancer+normal)

(normal vs normal)

10- cgl675547 (cancer vs cancer) cg06326667 (normal vs normal) 16-4802990

133950900 5 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

10- (normal vs normal) 16- cg0688093

cgl7851392 (cancer+normal vs

135120603 (cancer vs cancer) 57147300 0

cancer+normal)

10- 16- cg0873423 (cancer+normal vs cg04633922 (normal vs normal)

2699291 87744948 7 cancer+normal)

10- 16- cg0048874 (cancer+normal vs cg09115646 (normal vs normal)

2978687 89445503 7 cancer+normal)

10- 17- cg0977485 (cancer+normal vs cgl5969149 (normal vs normal)

77352287 30539553 4 cancer+normal)

10- 17- cg2121450 (cancer+normal vs cg08542351 (normal vs normal)

77352376 44248233 8 cancer+normal)

(cancer vs cancer)

11- cg0687134

cg03893663 (normal vs normal) 17-452707 (cancer+normal vs

110067118 4

cancer+normal)

11- cg25859670 (normal vs normal) 17- cgl228079 (normal vs normal) 132031417 48856029 8 (cancer vs cancer)

(cancer+normal vs cancer+normal)

11- 17- cgl284084 (cancer+normal vs cg02516944 (normal vs normal)

132031665 75208309 7 cancer+normal)

11- 18- cg2524967 (cancer+normal vs cgO 1140660 (normal vs normal)

133233200 77485710 0 cancer+normal)

(normal vs normal)

11- (normal vs normal) cg2589995 (cancer vs cancer) cg24137774 18-8660164

19372014 (cancer vs cancer) 4 (cancer+normal vs

cancer+normal)

(normal vs normal)

11- cgl351341 (cancer vs cancer) cgO 1229760 (normal vs normal) 19-4676202

7728104 1 (cancer+normal vs

cancer+normal)

(normal vs normal)

12- cgl832861 (cancer vs cancer) cg24630957 (normal vs normal) 19-4676623

105503674 2 (cancer+normal vs

cancer+normal)

12- cg0792100 (cancer+normal vs cg07385694 (normal vs normal) 2-10924176

132900464 8 cancer+normal)

(normal vs normal)

12- cg0685615 (cancer vs cancer) cgl5866393 (normal vs normal) 2-11774852

132900480 5 (cancer+normal vs

cancer+normal)

12- 2- cg2210978 (cancer+normal vs cg24965248 (normal vs normal)

4554940 152108040 7 cancer+normal)

(normal vs normal)

12- 2- cgl745922

cgl 9018201 (normal vs normal) (cancer+normal vs

4554962 239074497 5

cancer+normal)

(normal vs normal)

13- cg0002708 (cancer vs cancer) cgl4807553 (normal vs normal) 2-3325158

113533425 1 (cancer+normal vs

cancer+normal)

(normal vs normal)

13- cg0469438 (cancer vs cancer) cg06509223 (normal vs normal) 2-69857465

23422746 9 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

13- 20- cgl789429

cg20196215 (normal vs normal) (cancer+normal vs

23422801 32436418 3

cancer+normal)

(cancer vs cancer)

13- 20- cg0017116

cgl0416814 (normal vs normal) (cancer+normal vs

23422850 35444275 6

cancer+normal)

(normal vs normal)

13- (normal vs normal) 20- cg0681404 (cancer vs cancer) cg08418978

96085969 (cancer vs cancer) 35444364 8 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

13- (normal vs normal) 20- cg0820918

cg22122715 (cancer+normal vs

96086023 (cancer vs cancer) 35444560 4

cancer+normal)

(normal vs normal)

(cancer vs cancer) (normal vs normal)

13- 21- cg2701182

cg20278383 (cancer vs cancer) (cancer+normal vs

96086098 40559999 9

(cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

15- 22- cg2715705

cg24602704 (normal vs normal) (cancer+normal vs

25951163 42563204 0

cancer+normal)

15- (normal vs normal) 22- cgl331812 (cancer vs cancer) cgO 1666796

70364327 (cancer vs cancer) 45737514 9 (cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

16- (normal vs normal) 3- cg0039595

cg02498072 (cancer+normal vs

12088037 (cancer vs cancer) 113413263 1

cancer+normal)

(cancer vs cancer)

16- cg0213113

cgl0278915 (normal vs normal) 3-11597868 (cancer+normal vs

88361441 0

cancer+normal)

(cancer vs cancer)

16- cg2139651

cg27092995 (normal vs normal) 3-11655466 (cancer+normal vs

88826522 7

cancer+normal)

(normal vs normal)

16- 3- cg2593113 (cancer vs cancer) cg02154436 (normal vs normal)

88826569 195709698 8 (cancer+normal vs

cancer+normal)

(normal vs normal)

(normal vs normal) cgl372301 (cancer vs cancer)

16-981766 cg04170174 3-52737693

(cancer vs cancer) 1 (cancer+normal vs

cancer+normal)

(normal vs normal)

(normal vs normal) 4- cg0797938 (cancer vs cancer)

16-982031 cg06993367

(cancer vs cancer) 169573255 8 (cancer+normal vs

cancer+normal)

(normal vs normal) (normal vs normal)

17- (cancer vs cancer) 4- cg0955714 (cancer vs cancer) cg25567048

18854799 (cancer+normal vs 183816164 9 (cancer+normal vs

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

17- (cancer vs cancer) 4- cg0739682

cg00306284 (cancer+normal vs

18855313 (cancer+normal vs 184683218 7

cancer+normal) cancer+normal)

(normal vs normal) (normal vs normal)

17- (cancer vs cancer) 4- cg0922753 (cancer vs cancer) cg09632029

18855506 (cancer+normal vs 186945339 3 (cancer+normal vs

cancer+normal) cancer+normal)

(normal vs normal)

17- cgl857976 (cancer vs cancer) cg26885619 (normal vs normal) 4-83323585

39471907 1 (cancer+normal vs

cancer+normal)

(normal vs normal)

17- 5- cg0101811 (cancer vs cancer) cgl 1486359 (normal vs normal)

4489504 134814626 0 (cancer+normal vs

cancer+normal)

(normal vs normal)

17- cg0664662 (cancer vs cancer) cg03156170 (normal vs normal) 5-78766902

55673870 2 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

17- 6- cg0198143

cg07992457 (normal vs normal) (cancer+normal vs

71744924 138200309 3

cancer+normal)

17- 6- cgl828776 (cancer+normal vs cgl9267213 (normal vs normal)

74908714 138200387 8 cancer+normal)

(cancer vs cancer)

17- 6- cg0506650

cgl6145211 (normal vs normal) (cancer+normal vs

75695378 169978311 3

cancer+normal)

(cancer vs cancer)

18- 6- cgl321183

cg00989538 (normal vs normal) (cancer+normal vs

74832115 169978387 2

cancer+normal)

(normal vs normal) (cancer vs cancer)

18- 6- cg2537343

cg21116087 (cancer vs cancer) (cancer+normal vs

74832171 170028109 8

(cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal) (normal vs normal)

18- (cancer vs cancer) cg2137679 (cancer vs cancer) cgl6990945 6-30094960

74832261 (cancer+normal vs 9 (cancer+normal vs

cancer+normal) cancer+normal)

(normal vs normal)

18- 7- cg0098297 (cancer vs cancer) cgl9355932 (normal vs normal)

76151203 101522290 4 (cancer+normal vs

cancer+normal)

(normal vs normal)

(cancer vs cancer)

19- (cancer vs cancer) 7- cg0303281

cgl2249345 (cancer+normal vs

45316493 (cancer+normal vs 134613526 6

cancer+normal) cancer+normal)

(normal vs normal) (normal vs normal)

19- (cancer vs cancer) cgl836538 (cancer vs cancer) cg21978694 7-33725819

45316509 (cancer+normal vs 3 (cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

19- cg2239955

cg24128045 (normal vs normal) 7-5529868 (cancer+normal vs

54174606 5

cancer+normal)

(cancer vs cancer)

19- 8- cg0544577

cgl 1225056 (normal vs normal) (cancer+normal vs

55874500 126202653 2

cancer+normal)

(normal vs normal)

2- cg2551598 (cancer vs cancer) cg25207147 (normal vs normal) 8-12860315

178973079 2 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

2- 9- cgl417728

cg24655222 (normal vs normal) (cancer+normal vs

27601647 126153067 9

cancer+normal)

(normal vs normal)

9- cgl359555 (cancer vs cancer)

2-3826980 cgl4989714 (normal vs normal)

129648322 6 (cancer+normal vs

cancer+normal)

21- cg07529658 (normal vs normal) (normal vs normal)

46845160

cgl8063278 (normal vs normal) Status - Hyper

12328740

(cancer vs cancer)

4- cg0596018 (normal vs normal) cg08577953 (normal vs normal) 1-16160360

100574455 2 (cancer+normal vs

cancer+normal)

(normal vs normal)

4- 1- cg0484620

cgl5375311 (normal vs normal) (cancer+normal vs

25621615 167690438 3

cancer+normal)

4- (normal vs normal) 1- cg2171032

cg05617027 (normal vs normal)

40437086 (cancer vs cancer) 226069189 4

1- cg0389068

5-2866465 cgl3945749 (normal vs normal) (normal vs normal)

227504721 0

1- cg0954840

5-6491884 cgl6612423 (normal vs normal) (normal vs normal)

232840764 3

5- (normal vs normal) cg0534687

cgl0572670 1-59043576 (normal vs normal)

73112528 (cancer vs cancer) 8

(normal vs normal)

6- (cancer vs cancer) cg2739849

cg25545503 1-59043873 (normal vs normal)

160680162 (cancer+normal vs 9

cancer+normal)

(cancer vs cancer)

6- 10- cgl425541 (normal vs normal) cgl0832035 (normal vs normal)

170564889 104417977 7 (cancer+normal vs

cancer+normal) 6- 10- cg2523390

cg08623515 (normal vs normal) (normal vs normal)

170565117 133793646 0

7- 10- cg2747822

cg07302677 (normal vs normal) (normal vs normal)

128550862 91061115 4

7- 10- cg2560392

cgl7533927 (normal vs normal) (normal vs normal)

128550898 99185264 7

7- 11- cgl770727

cg05222671 (normal vs normal) (normal vs normal)

130130155 102401523 4

(cancer vs cancer)

7- 11- cg0181307 (normal vs normal) cgl3476800 (normal vs normal)

132500307 102401616 1 (cancer+normal vs cancer+normal)

7- 11- cg0243126

cg03734783 (normal vs normal) (normal vs normal)

150745709 124628888 0

(normal vs normal)

7- cgl428929

cgl4840782 (normal vs normal) 11-1974984 (cancer+normal vs

157280331 4

cancer+normal)

7- 11- cg0621868

cgl5689733 (normal vs normal) (normal vs normal)

157444235 19799429 8

7- 11- cg2437416

cgl4462553 (normal vs normal) (normal vs normal)

157444239 46582058 1

7- 11- cgl282207

cgl6796151 (normal vs normal) (normal vs normal)

157447244 57243865 4

(cancer vs cancer)

7- 11- cg0603820 (normal vs normal) cgl0249637 (normal vs normal)

157655436 65487505 1 (cancer+normal vs cancer+normal)

7- 11- cgl705847

cg09941017 (normal vs normal) (normal vs normal)

157688504 68607737 5

7- 11- cg0474020

cg02650121 (normal vs normal) (normal vs normal)

36124562 82871065 5

7- 12- cg0180419

cg05754377 (normal vs normal) (normal vs normal)

36124944 63026212 3

(cancer vs cancer)

13- cg0558594 (normal vs normal)

7-5161165 cg05058150 (normal vs normal)

20699452 7 (cancer+normal vs cancer+normal)

7- (normal vs normal) 13- cg2507273

cgl8966688 (normal vs normal)

70096458 (cancer vs cancer) 37249481 3

7- 13- cg0801858

cgl6443009 (normal vs normal) (normal vs normal)

75864075 46425866 5

7- 13- cg0201753

cgl9312058 (normal vs normal) (normal vs normal)

94289851 46425999 4

8- 14- cg2731231 (cancer vs cancer) cg03385495 (normal vs normal)

49747620 56046001 2 (normal vs normal)

14- cgl690751

8-709576 cg04027411 (normal vs normal) (normal vs normal)

56046098 4

14- cg0161101

8-709624 cg09959150 (normal vs normal) (normal vs normal)

95780344 7

(cancer vs cancer)

9- (normal vs normal) 15- cg0020065 (normal vs normal) cgl3595739

37340211 (cancer vs cancer) 60883225 3 (cancer+normal vs cancer+normal)

KiCaG (cancer vs 15- cg0598409

(normal vs normal) cancer) 75075998 6

15- cg0256697

Status - Hyper (normal vs normal)

75076251 8

(cancer vs cancer)

1- (cancer vs cancer) 17- cg0783273

cg08911820 (normal vs normal)

110026001 (cancer+normal vs 11142923 8

cancer+normal) (cancer vs cancer)

1- (cancer vs cancer) cg2363042

cg24000437 17-1903022 (normal vs normal)

152538857 (cancer+normal vs 3

cancer+normal)

1- 17- cg0089787

cgl2200412 (cancer vs cancer) (normal vs normal)

158324331 43392165 5

(cancer vs cancer)

1- (cancer vs cancer) 17- cg2568326

cgl0061342 (normal vs normal)

184357556 (cancer+normal vs 53809564 8

cancer+normal)

1- 17- cg0209076

cg24159697 (cancer vs cancer) (normal vs normal)

205181237 79503859 2

1- 17- cgl225213

cg08706732 (cancer vs cancer) (normal vs normal)

29448625 79503877 5

(cancer vs cancer)

1- (cancer vs cancer) cg0465802

cg26042300 17-8056967 (normal vs normal)

40887988 (cancer+normal vs 1

cancer+normal)

10- (cancer vs cancer) 18- cgl506982

cg20095124 (normal vs normal)

102588691 (normal vs normal) 11752904 3

(cancer vs cancer)

(cancer vs cancer)

10- 18- cg2422853

cgl7480467 (normal vs normal) (normal vs normal)

102588959 76002290 2

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- 2- cg0432062

cgl4778235 (normal vs normal) (normal vs normal)

102589102 178013040 9

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

10- 2- cg2021846

cg08217716 (normal vs normal) (normal vs normal)

102589250 238583504 0

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

10- cgl 138032 (normal vs normal) cgl 8047662 (cancer vs cancer) 2-24715213

129534217 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

10- 21- cg2639059 (normal vs normal) cgl0492836 (cancer vs cancer)

134801824 41032396 8 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 21- cgl 125008

10-375391 cg06193766 (normal vs normal)

(cancer+normal vs 46126104 1

cancer+normal)

11- 21- cgl968341

cgl0825530 (cancer vs cancer) (normal vs normal)

16023708 46129392 0

11- 22- cgl442573

cg09951637 (cancer vs cancer) (normal vs normal)

33951810 46451214 3

(cancer vs cancer)

11- (cancer vs cancer) 22- cg2298276

cgl3563074 (normal vs normal)

7728814 (cancer+normal vs 46454012 7

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

12- 22- cg2733835 (normal vs normal) cg08752459 (normal vs normal)

10022682 46471129 3 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

12- cgl2591315 (cancer vs cancer) 3- cgl014828 (normal vs normal) 10022688 (cancer vs cancer) 148846750 0

(normal vs normal)

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (cancer vs cancer)

12- cg2557204

cg03800721 (normal vs normal)

(normal vs normal) 3-15839627

120525338 3

(cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) 3- cg2164393

cg25969992

121088408 (normal vs normal)

(cancer+normal vs 172467326 9

cancer+normal)

12- 3- cg2543663

cgl4808040 (cancer vs cancer)

124418532 (normal vs normal)

181045270 4

(cancer vs cancer)

12- 3- cg0146517

cg23795633 (cancer vs cancer) (normal vs normal)

131417943 182208536 7 (cancer+normal vs cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cg0029410

cgl9495013 3-3219781

52214119 (normal vs normal)

(cancer+normal vs 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- (cancer vs cancer) _C gl944460

cg07375978 (normal vs normal)

3-44039204

52214320 (cancer+normal vs 9 (cancer+normal vs cancer+normal) cancer+normal)

12- cgl989087

cg27178293 (cancer vs cancer) 3-44039289

54371246 (normal vs normal)

9

(cancer vs cancer) (cancer vs cancer)

12- (cancer vs cancer) cg0728930 (normal vs normal) cgl2232783 3-44039357

54422127 (cancer+normal vs 6 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cg0185652

cg27441225 (cancer vs cancer)

3-44039509

54422350 (cancer+normal vs 5 (normal vs normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cg0388954 (cancer vs cancer) cg22378817 3-44039578

54422488 (cancer+normal vs 2 (normal vs normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cgl761497

cgl6983211 3-44039919

54427636 (normal vs normal)

(cancer+normal vs 4

cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cgl721932

cgl5700739 3-44517846

54427700 (normal vs normal)

(cancer+normal vs 6

cancer+normal)

12- cg0714691

cgl 1794356 (cancer vs cancer) 3-73671377

55725991 (normal vs normal)

2

(cancer vs cancer)

13- (cancer vs cancer) cg0493112

cg01866427 3-78084695

113598068 (normal vs normal)

(cancer+normal vs 6

cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) 4- cg2396593 (cancer vs cancer) cg02223067

113623233 (cancer+normal vs 184828386 1 (normal vs normal) cancer+normal)

13- (cancer vs cancer) 4- cg0627784 (cancer vs cancer) cgl6737670

113623300 (cancer vs cancer) 186316674 9 (normal vs normal) (cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

13- 5- cgO 186006

cgOO 127894 (normal vs normal) (normal vs normal)

113623639 100237986 3

(cancer+normal vs

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- (cancer vs cancer) 5- cgl751928 (normal vs normal) cgl5179805

113623659 (cancer+normal vs 115175001 0 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

(cancer vs cancer)

13- 5- cg0719530 (normal vs normal) cg09678836 (normal vs normal)

113623844 121648993 1 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

13- 5- cg0599815 (normal vs normal) cg26087651 (cancer vs cancer)

22836354 134075279 3 (cancer+normal vs cancer+normal)

15- 5- cgl747376

cg07398661 (cancer vs cancer) (normal vs normal)

37111929 139016709 5

(normal vs normal)

15- (cancer vs cancer) cgl469765

cg24340572 5-42858327 (cancer+normal vs

69887053 (normal vs normal) 7

cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer) cg2654000

cgl6973527 5-54932693 (normal vs normal)

70767570 (cancer+normal vs 4

cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer) cg0783277

cgl3427748 5-8461832 (normal vs normal)

70767649 (cancer+normal vs 2

cancer+normal)

(cancer vs cancer)

16- 6- cg2544114 (normal vs normal) cg26757472 (cancer vs cancer)

86387131 113012601 1 (cancer+normal vs cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 6- cgl522627

cgl4807365 (normal vs normal)

18908235 (cancer+normal vs 116381976 5

cancer+normal)

(cancer vs cancer)

(normal vs normal)

17- (cancer vs cancer) 6- cgl322145

cg22220165 (cancer+normal vs

18908242 (cancer+normal vs 160112632 8

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) 6- cg0765223

cgl6293732 (normal vs normal)

35289543 (cancer+normal vs 170125491 7

cancer+normal)

17- (cancer vs cancer) cgl317532

cg06683719 6-25035073 (normal vs normal)

5673550 (cancer vs cancer) 9

17- 7- cgl573085

cg20752878 (cancer vs cancer) (normal vs normal)

7080538 116592968 7

(cancer vs cancer)

17- (cancer vs cancer) cgl015543

cg21068610 7-1293933 (normal vs normal)

7790179 (cancer+normal vs 2

cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) 7- cg0645603

cgl8596381 (normal vs normal)

11199917 (cancer+normal vs 134832850 1

cancer+normal) (cancer vs cancer) (cancer vs cancer)

19- (cancer vs cancer) cg2646843 (normal vs normal) cgl9751789 7-1572571

11199944 (cancer+normal vs 0 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cg0370759

cgl2013591 7-75956931 (normal vs normal)

11199965 (cancer+normal vs 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- (cancer vs cancer) cg2541800 (normal vs normal) cgl5746620 7-79780310

14785849 (cancer+normal vs 1 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

19- (normal vs normal) cg2750478

cg26988138 7-94284258 (normal vs normal)

2639424 (cancer+normal vs 2

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl714673

cg00506866 7-98739698 (normal vs normal)

10263480 (cancer+normal vs 8

cancer+normal)

(cancer vs cancer)

2- cgl404185

cgl9516340 (cancer+normal vs 8-1068250 (normal vs normal)

10263696 5

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) 8- cgl327087

cg20219891 (normal vs normal)

121496875 (cancer+normal vs 116660311 3

cancer+normal)

(cancer vs cancer)

2- 8- cg0602334 (normal vs normal) cgl8968409 (cancer vs cancer)

34633637 127568650 5 (cancer+normal vs cancer+normal)

(cancer vs cancer)

2- 8- cgO 192399 (normal vs normal) cgl2884814 (cancer vs cancer)

50718584 127568677 9 (cancer+normal vs cancer+normal)

2- cgl470925

cgl6256243 (cancer vs cancer) 8-17519419 (normal vs normal)

85648512 3

20- cgl594476

cg08292485 (cancer vs cancer) 8-29210790 (normal vs normal)

29993663 6

20- cg0051087

cg08460399 (cancer vs cancer) 8-29210800 (normal vs normal) 42879935 0

20- cgl403677

cgO 1360605 (cancer vs cancer) 8-37595363 (normal vs normal)

58983676 6

(cancer vs cancer)

20- cg0330108 (normal vs normal) cg01575590 (cancer vs cancer) 8-80679314

62084626 4 (cancer+normal vs cancer+normal)

(cancer vs cancer)

22- cg2062925

cgl4742445 (cancer+normal vs 8-81491905 (normal vs normal) 30195299 4

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- (cancer vs cancer) cg0753833

cg00589251 (normal vs normal)

8-93107298

132036382 (cancer+normal vs 9 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- (cancer vs cancer) cg0250171 (normal vs normal) cgl5903185 9-89560185

111530471 (cancer+normal vs 4 (cancer+normal vs cancer+normal) cancer+normal)

4-9917839 cgl4959260 (cancer vs cancer) Status - Hypo

(cancer vs cancer) cg2691938 (normal vs normal)

5-1406177 cg24756227 1-10676290

(cancer+normal vs 7 (cancer vs cancer) cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer) (normal vs normal)

5- (cancer vs cancer) 1- cg2323287 (cancer vs cancer) cgl8086386

162516650 (cancer+normal vs 113819171 3 (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

1- cg0811362 (cancer vs cancer)

5-5033993 cg08596532 (cancer vs cancer)

182570870 8 (cancer+normal vs cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- cg0782116

cg02632185 (normal vs normal) 1-28504285 (normal vs normal)

66299786 0

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

5- (cancer vs cancer) cgl386703

cgl8118497 1-3159645 (normal vs normal)

66299875 (cancer+normal vs 9

cancer+normal)

(cancer vs cancer)

(normal vs normal) (cancer vs cancer)

5- cgl822945 (cancer vs cancer) cgl7449851 (normal vs normal) 1-58622038

66300406 7 (cancer+normal vs

(cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

5- cgl453103

cgl 1831286 (normal vs normal) 1-8045077 (normal vs normal)

66300433 8

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) (normal vs normal)

5- 10- cgl659605

cg27116842 (normal vs normal) (cancer+normal vs

66300503 121271746 2

(cancer+normal vs cancer+normal) cancer+normal)

5- (cancer vs cancer) 10- cg0064435

cg25113089 (normal vs normal)

72598192 (normal vs normal) 121271840 1

(normal vs normal)

5- 10- cgl696057 (cancer vs cancer) cg22987011 (cancer vs cancer)

75753776 131200784 3 (cancer+normal vs cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 10- cg2632829 (normal vs normal) cg07571531

134216081 (cancer+normal vs 131200802 1 (cancer vs cancer) cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 10- cg2701452

cg23756442 (normal vs normal)

28892465 (cancer+normal vs 131200834 2

cancer+normal)

(normal vs normal)

6- 10- cgl 164214 (cancer vs cancer) cg04321126 (cancer vs cancer)

39393690 134559553 0 (cancer+normal vs cancer+normal)

(normal vs normal)

7- 10- cgl775094 (cancer vs cancer) cgl8323749 (cancer vs cancer)

128530795 134559637 6 (cancer+normal vs cancer+normal)

(normal vs normal)

7- 10- cg0792795 (cancer vs cancer) cg08922068 (cancer vs cancer)

128530800 134559696 3 (cancer+normal vs cancer+normal)

7- cg07039423 (cancer vs cancer) 10- cgl705478 (normal vs normal) 128531106 (normal vs normal) 134559939 3 (cancer vs cancer)

(cancer+normal vs cancer+normal)

7- 10- cg0929907

cg22939733 (cancer vs cancer) (normal vs normal)

128531165 76154015 5

(normal vs normal)

7- 11- cgl013183 (cancer vs cancer) cg00682002 (cancer vs cancer)

128531479 111167086 6 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

7- (cancer vs cancer) 11- cgl 198534

cg08986767 (normal vs normal)

92747308 (cancer+normal vs 129722477 1

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cg0505286

cg07554329 (normal vs normal)

107669778 (cancer+normal vs 134335356 9

cancer+normal)

(cancer vs cancer) (normal vs normal)

8- (cancer vs cancer) 11- cgl542752 (cancer vs cancer) cgl7136799

107669783 (cancer+normal vs 35252384 0 (cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

(normal vs normal)

8- (cancer vs cancer) cg0245334

cg26622232 11-3638458 (cancer+normal vs

107669787 (cancer+normal vs 8

cancer+normal) cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cg0878843

cgl7176732 (normal vs normal)

107669856 (cancer+normal vs 63870619 8

cancer+normal)

(cancer vs cancer)

(normal vs normal)

8- (cancer vs cancer) 11- cg0778318

cgl7212289 (cancer+normal vs

107669906 (cancer+normal vs 75852355 3

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

8- (cancer vs cancer) 11- cg2463051 (cancer vs cancer) cgl6326979

107670161 (cancer+normal vs 75852389 6 (cancer+normal vs

cancer+normal) cancer+normal)

(normal vs normal)

8- 11- cgl923441 (cancer vs cancer) cg06162872 (cancer vs cancer)

25546737 78638670 2 (cancer+normal vs

cancer+normal)

(cancer vs cancer) (normal vs normal)

8- (cancer vs cancer) 12- cg2271494 (cancer vs cancer) cgl3242160

55294610 (cancer+normal vs 109911508 2 (cancer+normal vs

cancer+normal) cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 12- cg2649181

cg07664990 (normal vs normal)

55294721 (cancer+normal vs 130961949 8

cancer+normal)

8- 12- cgl428889

cg24039394 (cancer vs cancer) (normal vs normal)

55294823 132901741 0

(normal vs normal)

8- cgl313027 (cancer vs cancer) cgl0239077 (cancer vs cancer) 12-3030602

55294882 4 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

9- (cancer vs cancer) cg2752833

cgl4341131 12-7025947 (normal vs normal)

138605049 (cancer+normal vs 0

cancer+normal)

13- cg0408963

Status - Hypo (normal vs normal)

105987461 7 1- 13- cg2567815

cgl7501774 (cancer vs cancer) (normal vs normal)

120174801 113488452 0

(cancer vs cancer)

1- (cancer vs cancer) 14- cgl850838

cgl0325088 (normal vs normal)

217724849 (cancer+normal vs 51171931 9

cancer+normal)

1- 14- cgl 106473

cg02452586 (cancer vs cancer) (normal vs normal)

233497903 68985557 8

1- 14- cg0900522

cg09347582 (cancer vs cancer) (normal vs normal)

233497916 80676940 1

(normal vs normal)

15- cg0803628 (cancer vs cancer)

1-8931135 cgl3785123 (cancer vs cancer)

40677854 9 (cancer+normal vs cancer+normal)

10- (normal vs normal) 15- cg0757540

cgl7851392 (normal vs normal)

135120603 (cancer vs cancer) 66541975 7

(normal vs normal)

10- cg0392974 (cancer vs cancer) cg04070692 (cancer vs cancer) 16-2282618

135120640 7 (cancer+normal vs cancer+normal)

(normal vs normal)

10- cgl027804 (cancer vs cancer) cgl 1801524 (cancer vs cancer) 16-4802848

29811563 6 (cancer+normal vs cancer+normal)

(normal vs normal)

10- cgl675547 (cancer vs cancer) cg07225966 (cancer vs cancer) 16-4802990

94820376 5 (cancer+normal vs cancer+normal)

11- 16- cg2175744

cg07364154 (cancer vs cancer) (normal vs normal)

108018824 58031050 0

11- 16- cg2745953

cgl 1286122 (cancer vs cancer) (normal vs normal)

118477406 87744906 0

(normal vs normal)

11- 17- cgl228079 (cancer vs cancer) cg00509007 (cancer vs cancer)

1781557 48856029 8 (cancer+normal vs cancer+normal)

11- (normal vs normal) 17- cg0460881

cg24137774 (normal vs normal)

19372014 (cancer vs cancer) 74671934 1

11- 18- cg0347704

cg01693193 (cancer vs cancer) (normal vs normal)

2705153 30347555 9

(cancer vs cancer)

11- (cancer vs cancer) cgl930571

cg21039563 18-8659964 (normal vs normal)

64323816 (cancer+normal vs 8

cancer+normal)

(normal vs normal) cg2589995 (cancer vs cancer)

11-945202 cg03278299 (cancer vs cancer) 18-8660164

4 (cancer+normal vs cancer+normal)

12- 19- cgl514784

cg07058694 (cancer vs cancer) (normal vs normal)

111909145 46033285 1

12- 19- cgl 127605

cg06912420 (cancer vs cancer) (normal vs normal)

14617656 46307734 3

12- 19- cg0235977

cgl l362183 (cancer vs cancer) (normal vs normal)

64403751 46307846 3

(normal vs normal)

12- cgl351341 (cancer vs cancer) cgl 1681462 (cancer vs cancer) 19-4676202

69417830 1 (cancer+normal vs cancer+normal)

(cancer vs cancer) (normal vs normal)

12- cgl832861

cg24859375 (cancer vs cancer) 19-4676623 (cancer vs cancer)

7121914 2

(cancer+normal vs (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

13- (cancer vs cancer) cgl759538

cg21980364 2-11774474 (normal vs normal) 111880998 (cancer+normal vs 6

cancer+normal)

(normal vs normal)

13- cg0685615 (cancer vs cancer) cgl2557626 (cancer vs cancer) 2-11774852

113977332 5 (cancer+normal vs

cancer+normal)

13- cgl601603

cg21708867 (cancer vs cancer) 2-1417109 (normal vs normal) 114138225 6

(cancer vs cancer)

13- (cancer vs cancer) cgl268013

cg21238257 2-1417153 (normal vs normal) 114138260 (cancer+normal vs 1

cancer+normal)

13- (normal vs normal) cg0650072

cg08418978 2-1417164 (normal vs normal)

96085969 (cancer vs cancer) 7

13- (normal vs normal) cgl037059

cg22122715 2-1417431 (normal vs normal)

96086023 (cancer vs cancer) 1

(normal vs normal)

(cancer vs cancer)

13- cg2313664

cg20278383 (cancer vs cancer) 2-1418073 (normal vs normal)

96086098 5

(cancer+normal vs

cancer+normal)

13- 2- cg0364130

cg27586249 (cancer vs cancer) (normal vs normal)

96086182 160917029 0

13- 2- cg0478976

cg04246521 (cancer vs cancer) (normal vs normal)

96086275 175431800 1

14- 2- cg0882634

cg07067667 (cancer vs cancer) (normal vs normal)

68592625 208331979 5

(normal vs normal)

14- 2- cgl745922

cg04246305 (cancer vs cancer) (cancer+normal vs

75549272 239074497 5

cancer+normal)

15- 2- cgl725755

cg04861869 (cancer vs cancer) (normal vs normal)

101728611 242004824 4

15- cg2424831

cgl4397171 (cancer vs cancer) 2-26986379 (normal vs normal)

101728653 7

(normal vs normal)

15- cg0002708 (cancer vs cancer) cg24405716 (cancer vs cancer) 2-3325158

31280513 1 (cancer+normal vs

cancer+normal)

15- cg0614973

cg25634457 (cancer vs cancer) 2-39876715 (normal vs normal)

63610813 3

15- cg0342757

cg24310913 (cancer vs cancer) 2-61809639 (normal vs normal)

63875268 7

(normal vs normal)

15- cg0469438 (cancer vs cancer) cg20082641 (cancer vs cancer) 2-69857465

69590255 9 (cancer+normal vs

cancer+normal)

(normal vs normal)

16- (normal vs normal) 20- cg0681404 (cancer vs cancer) cg02498072

12088037 (cancer vs cancer) 35444364 8 (cancer+normal vs

cancer+normal)

(cancer vs cancer)

(normal vs normal)

16- (cancer vs cancer) 21- cg2701182

cg06978461 (cancer+normal vs

15127193 (cancer+normal vs 40559999 9

cancer+normal) cancer+normal)

(normal vs normal)

16- 3- cg2593113 (cancer vs cancer) cg04908960 (cancer vs cancer)

30425679 195709698 8 (cancer+normal vs

cancer+normal) cg0028590

16-533228 cg08591538 (cancer vs cancer) 3-46605616 (normal vs normal)

2

(cancer vs cancer) (normal vs normal)

16- (cancer vs cancer) cgl372301 (cancer vs cancer) cg03212183 3-52737693

81565917 (cancer+normal vs 1 (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

16- 4- cg0797938 (cancer vs cancer) cg27391627 (cancer vs cancer)

86704130 169573255 8 (cancer+normal vs cancer+normal)

(normal vs normal)

(normal vs normal) 4- cg0955714 (cancer vs cancer)

16-981766 cg04170174

(cancer vs cancer) 183816164 9 (cancer+normal vs cancer+normal)

(normal vs normal) 4- cgl994591

16-982031 cg06993367 (normal vs normal)

(cancer vs cancer) 186945215 2

(cancer vs cancer) (normal vs normal)

17- (cancer vs cancer) 4- cg0922753 (cancer vs cancer) cgl8449048

18854760 (cancer+normal vs 186945339 3 (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal) (normal vs normal)

17- (cancer vs cancer) cgl857976 (cancer vs cancer) cg25567048 4-83323585

18854799 (cancer+normal vs 1 (cancer+normal vs cancer+normal) cancer+normal)

(normal vs normal)

17- 5- cg0101811 (cancer vs cancer) cg08041350 (cancer vs cancer)

25819112 134814626 0 (cancer+normal vs cancer+normal)

17- 5- cg2699428

cg08585669 (cancer vs cancer) (normal vs normal)

37853032 177964757 3

(cancer vs cancer)

17- (cancer vs cancer) cgl467093

cg06975080 5-1927225 (normal vs normal)

78700928 (cancer+normal vs 8

cancer+normal)

19- cg0566493

cg21480173 (cancer vs cancer) 5-53915380 (normal vs normal)

10463831 8

(normal vs normal)

19- cg0664662 (cancer vs cancer) cgl8038269 (cancer vs cancer) 5-78766902

10464320 2 (cancer+normal vs cancer+normal)

19- 6- cg0542196

cgl 1575644 (cancer vs cancer) (normal vs normal)

10464711 126465314 5

19- 6- cg0061962

cg25367139 (cancer vs cancer) (normal vs normal)

1961185 151258451 8

19- cg2224713

cg22278901 (cancer vs cancer) 6-1523823 (normal vs normal)

1961290 6

(normal vs normal)

2- cg2137679 (cancer vs cancer) cgl3283952 (cancer vs cancer) 6-30094960

121412005 9 (cancer+normal vs cancer+normal)

(normal vs normal)

2- 7- cg0098297 (cancer vs cancer) cg04864807 (cancer vs cancer)

121412139 101522290 4 (cancer+normal vs cancer+normal)

2- 7- cgl469136

cgl 1432488 (cancer vs cancer) (normal vs normal)

180125932 126165242 4

(cancer vs cancer)

2- (cancer vs cancer) 7- cg2098589

cg26015513 (normal vs normal)

201218948 (cancer+normal vs 157778531 7

cancer+normal)

2- cg02371631 (cancer vs cancer) 7-33725819 cgl836538 (normal vs normal) 202748718 3 (cancer vs cancer)

(cancer+normal vs cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl420171

cg09473180 7-47679990 (normal vs normal)

217403190 (cancer+normal vs 7

cancer+normal)

2- cgl 102698

cg26186249 (cancer vs cancer) 7-6682784 (normal vs normal)

223538875 7

(normal vs normal)

2- cg2551598 (cancer vs cancer) cgl9752143 (cancer vs cancer) 8-12860315

44552508 2 (cancer+normal vs cancer+normal)

2- cg2393561

cgl6936561 (cancer vs cancer) 8-2112392 (normal vs normal)

73338081 6

(normal vs normal)

2- 9- cgl359555 (cancer vs cancer) cgl4245791 (cancer vs cancer)

99917669 129648322 6 (cancer+normal vs cancer+normal)

20- 9- cgl953494

cg07733918 (cancer vs cancer) (normal vs normal)

33100246 139847558 5

20- cgl461230

cg22423984 (cancer vs cancer) 9-16214627 (normal vs normal)

34734501 3

(cancer vs cancer)

20- (cancer vs cancer) UCEC (cancer vs

cg21209310

6025272 (cancer+normal vs cancer)

cancer+normal)

22- cgl9092981 (cancer vs cancer) Status - Hyper

19751654

(cancer vs cancer)

3- (cancer vs cancer) 1- cgl357439

cgl l011913 (cancer vs cancer)

149051159 (cancer+normal vs 156815274 0

cancer+normal)

3- 1- cg2675705

cg09230938 (cancer vs cancer) (cancer vs cancer)

183722448 219347021 3

(cancer vs cancer)

4- 1- cg0219104

cg26017679 (cancer vs cancer) (cancer+normal vs

148936704 232940990 4

cancer+normal)

4- 1- cg0290390

cgl4022183 (cancer vs cancer) (cancer vs cancer)

187729190 232941055 7

4- (normal vs normal) 1- cgl554279

cg05617027 (cancer vs cancer)

40437086 (cancer vs cancer) 232941253 8

4- cgl 182463

cgl7864469 (cancer vs cancer) 1-67218080 (cancer vs cancer)

77877357 9

4- cg0931837

cg21520613 (cancer vs cancer) 1-67218090 (cancer vs cancer)

77891275 5

(cancer vs cancer)

4- (cancer vs cancer) 10- cg0562702

cg27000934 (cancer vs cancer)

87993109 (cancer+normal vs 122708532 9

cancer+normal)

(cancer vs cancer)

5- 10- cgl247402

cg22862094 (cancer vs cancer) (cancer+normal vs

106859865 124639132 3

cancer+normal)

(cancer vs cancer)

5- 12- cgl 122541

cgl l l59417 (cancer vs cancer) (cancer+normal vs

148822491 93966317 0

cancer+normal)

(cancer vs cancer)

5- (normal vs normal) 12- cg2212537

cgl0572670 (cancer+normal vs

73112528 (cancer vs cancer) 93966485 0

cancer+normal)

6- 14- cg2341833

cg03944099 (cancer vs cancer) (cancer vs cancer)

108928210 103655424 9 6- 14- cg0519461

cgl6036022 (cancer vs cancer) (cancer vs cancer)

30885008 45432309 8

(cancer vs cancer)

6- 16- cgl636470

cgl5673491 (cancer vs cancer) (cancer+normal vs

30885481 23724485 9

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

7- (cancer vs cancer) 17- cg0170358

cgl5600935 (cancer+normal vs

101556684 (cancer+normal vs 42030287 1

cancer+normal) cancer+normal)

7- 17- cg2583069

cg06294954 (cancer vs cancer) (cancer vs cancer)

101789639 42030479 6

(cancer vs cancer)

7- 17- cgl237320

cg00567872 (cancer vs cancer) (cancer+normal vs

101789685 42091713 8

cancer+normal)

(cancer vs cancer)

17- cg0487975

7-1055600 cg20821713 (cancer vs cancer) (cancer+normal vs

42091909 5

cancer+normal)

(cancer vs cancer)

7- 17- cgl880159

cgl7706086 (cancer vs cancer) (cancer+normal vs

130129946 42092187 9

cancer+normal)

(cancer vs cancer)

7- 17- cg2463864

cgOO 148025 (cancer vs cancer) (cancer+normal vs

133451621 42092247 7

cancer+normal)

(cancer vs cancer)

7- 17- cg2711681

cgl6564132 (cancer vs cancer) (cancer+normal vs

47193871 42092315 9

cancer+normal)

(cancer vs cancer)

7- 17- cg0837294

cg04089246 (cancer vs cancer) (cancer+normal vs

47579217 42092370 7

cancer+normal)

(cancer vs cancer)

7- (normal vs normal) 17- cg0651138

cgl8966688 (cancer+normal vs

70096458 (cancer vs cancer) 42092403 9

cancer+normal)

(cancer vs cancer)

17- cgl225925

7-807608 cg09533868 (cancer vs cancer) (cancer+normal vs

42092431 6

cancer+normal)

(cancer vs cancer)

17- cgl384706

7-811206 cg07803375 (cancer vs cancer) (cancer+normal vs

42092450 6

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- (cancer vs cancer) 17- cg0163519

cgl7018549 (cancer+normal vs

141147681 (cancer+normal vs 42092472 3

cancer+normal) cancer+normal)

(cancer vs cancer)

8- 17- cg2586828

cg26714129 (cancer vs cancer) (cancer+normal vs

142310710 42092488 6

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

8- (cancer vs cancer) 17- cg0198613

cgl4895559 (cancer+normal vs

30209391 (cancer+normal vs 42092588 1

cancer+normal) cancer+normal)

(cancer vs cancer)

8- 17- cgl017931

cgl3172905 (cancer vs cancer) (cancer+normal vs

30341765 58498871 5

cancer+normal)

(cancer vs cancer)

9- (normal vs normal) cg2596400

cgl3595739 17-9479910 (cancer+normal vs

37340211 (cancer vs cancer) 7

cancer+normal)

(cancer vs cancer)

LAML (cancer vs cgl261088

17-9479912 (cancer+normal vs cancer) 7

cancer+normal)

(cancer vs cancer) cg0539053

Status - Hyper 18-5238183 (cancer+normal vs

0

cancer+normal) (cancer vs cancer) (cancer vs cancer)

1- cgl429106

cgl3476072 (cancer+normal vs 18-5238200 (cancer+normal vs

149908313 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cgl525884

cg00777271 (cancer+normal vs 18-5238219 (cancer+normal vs

149908524 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg2075751

cg24620905 (cancer+normal vs 18-5238310 (cancer+normal vs

149908781 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cgl088596

cg20812370 (cancer+normal vs 18-5238589 (cancer+normal vs

164581169 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg2131102

cg03466326 (cancer+normal vs 18-5238608 (cancer+normal vs

205270559 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg2013424

cg05352688 (cancer+normal vs 18-5238708 (cancer+normal vs

211643515 1

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 19- cgl771156

cg24686918 (cancer+normal vs (cancer vs cancer)

221613658 44325008 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 19- cgl386152

cg05396897 (cancer+normal vs (cancer+normal vs

247611448 50836391 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 19- cg0101735

cg09226051 (cancer+normal vs (cancer+normal vs

247611502 50836561 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 19- cg0325128

cgl6400794 (cancer+normal vs (cancer+normal vs

27709850 50836910 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 19- cg2695279

cg25607920 (cancer+normal vs (cancer+normal vs

42384365 50860847 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 19- cgl215359

cg26038582 (cancer+normal vs (cancer+normal vs

42384390 50861047 3

cancer+normal) cancer+normal)

(cancer vs cancer)

1- cg0525045

cg07865091 (cancer+normal vs 19-9473565 (cancer vs cancer)

43814306 8

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cg0216985

cgl8856478 (cancer+normal vs (cancer+normal vs

43814358 110969641 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cg0857024

cg08706567 (cancer+normal vs (cancer+normal vs

43814983 110969853 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cg0325022

cgl3393721 (cancer+normal vs (cancer+normal vs

43815035 110970097 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 2- cg0906808

cgl 1748187 (cancer+normal vs (cancer+normal vs

114713108 110970204 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 2- cgl036643

cg00159523 (cancer+normal vs (cancer+normal vs

114713187 110970249 9

cancer+normal) cancer+normal)

(cancer vs cancer)

10- 2- cg2537138

cg05576619 (cancer+normal vs (cancer vs cancer)

17391003 157177665 5

cancer+normal)

(cancer vs cancer)

10- 2- cgl 185607

cgl l416811 (cancer+normal vs (cancer vs cancer)

63422630 157178165 8

cancer+normal)

10- cg07643225 (cancer vs cancer) 2- cg0006317 (cancer vs cancer) 63422633 (cancer+normal vs 228736253 4

cancer+normal)

(cancer vs cancer)

10- 2- cg2064761

cgl4789659 (cancer+normal vs

63809073 (cancer vs cancer)

228736258 0

cancer+normal)

(cancer vs cancer)

10- 2- cg2380789

cgl6401465 (cancer+normal vs

63809170 (cancer vs cancer)

228736357 0

cancer+normal)

(cancer vs cancer)

10- 2- cg0121637

cg20684110 (cancer+normal vs

64565750 (cancer vs cancer)

228736459 0

cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer)

21- cg0035960

cgl2474798 (cancer+normal vs

64565772 38935977 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer)

21- cg2348475

cg04858631 (cancer+normal vs

74035570 38935991 (cancer+normal vs

5

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer) cgl618858

cg03677069 (cancer+normal vs 3-10206396

88718317 (cancer+normal vs

9

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) cg26681847 cgl800785

(cancer+normal vs 3-10206537

120208749 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) cg0443775

cgl 1180921 (cancer+normal vs 3-10206628

57090226 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) cg0500259

cgl6127573 (cancer+normal vs 3-10206633

57532299 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) cgl 102930

cgl3771313 (cancer+normal vs 3-10206731

72533295 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer)

3- cg0277293

cgl3073224 (cancer+normal vs

117131523 125709198 (cancer+normal vs

5

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer)

3- cg2702069

cg01054110 (cancer+normal vs

125002332 169482358 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer)

J- cg2083904

cgl6402452 (cancer+normal vs

58129855 169482714 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer)

3- cgl549411

cg05892030 (cancer+normal vs

51431710 169482895 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer)

3- cgl559994

cgO 1424562 (cancer+normal vs

69256677 169482899 (cancer+normal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer)

3- cg0138976

cg06617636 (cancer+normal vs

69256690 169482968 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer)

3- cg2303650

cg08169020 (cancer+normal vs

69256888 169483025 (cancer+normal vs

8

cancer+normal) cancer+normal)

(cancer vs cancer)

14- cgl334805

cgl0099732 (cancer+normal vs 3-44727069

69256977 (cancer vs cancer)

9

cancer+normal)

(cancer vs cancer)

15- cg0899991

cgl0078511 (cancer+normal vs 3-44727106

39872032 (cancer vs cancer)

5

cancer+normal)

15- (cancer vs cancer) cg2415818

cg08433504 3-44727195

39872071 (cancer vs cancer)

(cancer+normal vs 7 cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer) cg01359532 cgl010838

75045126 (cancer+normal vs 3-44770937 (cancer+normal vs

9

cancer+normal) cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer) cg21238234 cg0207355

83879539 (cancer+normal vs 3-44770973 (cancer+normal vs

8

cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) cgl4301190 cg2483768

31159704 (cancer+normal vs 3-44771102 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) cg09316954 cg0293311

67687754 (cancer+normal vs 3-44771105 (cancer+normal vs

9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16- cg09642825 cg0268034

(cancer+normal vs 4-4871525 (normal vs normal) 87416230 1

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) cg06330621 5- cg0105475

87525461 (cancer+normal vs

138728685 (cancer+normal vs

5

cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) cg08196561 5- cg2476186

87525539 (cancer+normal vs

138728704 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cg24205387 5- cg0513768

1464972 (cancer+normal vs

138729068 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

17- cg22980156 5- cg0544913

15366916 (cancer+normal vs (cancer vs cancer)

138729245 6

cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cgl 9458020 cgl 598130

38473119 (cancer+normal vs 5-87981894 (cancer+normal vs

5

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 6- cgl9443920 cg0804148

40075879 (cancer+normal vs (cancer vs cancer)

100902470 1

cancer+normal)

(cancer vs cancer)

17- 6- cgl7179862 cgl717230

46681362 (cancer+normal vs (cancer vs cancer)

168533631 8

cancer+normal)

17- (cancer vs cancer) (cancer vs cancer) cg03803541 cg2247821

46681401 (cancer+normal vs 6-26043990 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

17- cgl7697835 cg0770123

75283832 (cancer+normal vs 6-26044220 (cancer vs cancer)

7

cancer+normal)

(cancer vs cancer)

17- cgl2871285 cg2642614

76713379 (cancer+normal vs 6-26044274 (cancer vs cancer)

2

cancer+normal)

(cancer vs cancer)

19- cgl7126555 cg0222186

10445516 (cancer+normal vs 6-26044338 (cancer vs cancer)

6

cancer+normal)

(cancer vs cancer)

19- cg21631439 cg0564637

10736448 (cancer+normal vs 6-26044460 (cancer vs cancer)

3

cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cg08846870 cgl743245

15568360 (cancer+normal vs 6-26045532

3 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cg0763617

cg23450038

2462961 (cancer+normal vs 6-26045534 (cancer+normal vs

8

cancer+normal) cancer+normal)

19- (cancer vs cancer)

cg05258935 cg2543896 (cancer vs cancer)

39086923 6-26045663

(cancer+normal vs -» (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

19- cg2757752

cg21869046 (cancer+normal vs 6-28367544 (cancer vs cancer)

41225005 7

cancer+normal)

(cancer vs cancer)

19- cg0922242

cg01057656 (cancer+normal vs 6-85132263 (cancer vs cancer)

45281140 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- cg2463197

cgl7100943 (cancer+normal vs 8-11059029 (cancer+normal vs

6459300 0

cancer+normal) cancer+normal)

(cancer vs cancer)

19- cg2667587

cgl 1734329 (cancer+normal vs 8-11059176 (cancer vs cancer)

7460671 6

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- cg2425537

cg22568423 (cancer+normal vs 8-65488069 (cancer+normal vs

8590567 1

cancer+normal) cancer+normal)

(cancer vs cancer)

19- _C g0444551

cg22987448 (cancer+normal vs 8-70947044 (cancer vs cancer)

8591364 2

cancer+normal)

(cancer vs cancer)

20- 9- cg0691225

cg23501964 (cancer+normal vs (cancer vs cancer) 19866810 104248926 2

cancer+normal)

(cancer vs cancer)

20- cg20918393 (cancer+normal vs Status - Hypo

19867136

cancer+normal)

(cancer vs cancer)

22- cg0439464

cg00147172 (cancer+normal vs 1-17350304 (cancer vs cancer)

46423604 1

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

22- 1- cg0576841

cgl8982286 (cancer+normal vs (cancer+normal vs 51136325 174417967 9

cancer+normal) cancer+normal)

(cancer vs cancer)

1- cg0339375

cg24627325 (cancer+normal vs (cancer vs cancer)

101882326 178992788 4

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg2657057

cg08979515 (cancer+normal vs (cancer+normal vs

111697575 220415655 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg0718464

cgl3029400 (cancer+normal vs (cancer+normal vs

141087190 233815158 3

cancer+normal) cancer+normal)

(cancer vs cancer)

cg0424833

cg02524983 (cancer+normal vs 1-31423071 (cancer vs cancer)

188012918 2

cancer+normal)

(cancer vs cancer)

cg0058154

cg03534375 (cancer+normal vs 1-31423283 (cancer vs cancer)

57743163 1

cancer+normal)

(cancer vs cancer)

cg0794753

cgl5172734 (cancer+normal vs 1-32252266 (cancer vs cancer)

57743377 1

cancer+normal)

(cancer vs cancer)

4- cg0401199

cg05601456 (cancer+normal vs 1-41326317 (cancer vs cancer)

114900431 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cg0001593

cgl0393744 (cancer+normal vs 1-46921746 (cancer+normal vs

159969703 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cg2097742

cg26741686 (cancer+normal vs 1-46921844 (cancer+normal vs

186318356 6

cancer+normal) cancer+normal)

(cancer vs cancer)

4- cg2384491

cg06704884 (cancer+normal vs 1-56352596 (cancer vs cancer)

40665353 0

cancer+normal) (cancer vs cancer) (cancer vs cancer)

5- 10- cgl985674

cg24100671 (cancer+normal vs (cancer+normal vs

10551547 124316636 9

cancer+normal) cancer+normal)

(cancer vs cancer)

5- 10- cgl889242

cg27024654 (cancer+normal vs (cancer vs cancer)

133904674 131034796 4

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- 10- cgl862913

cg26516362 (cancer+normal vs (cancer+normal vs

178986906 131592435 2

cancer+normal) cancer+normal)

(cancer vs cancer)

10- cg0265606

5-5271554 cg25485055 (cancer+normal vs (cancer vs cancer)

131592483 0

cancer+normal)

(cancer vs cancer)

6- 10- cg0219386

cgl3829419 (cancer+normal vs (cancer vs cancer)

143167279 16822712 1

cancer+normal)

(cancer vs cancer)

6- 10- cg0236044

cgl4296767 (cancer+normal vs (cancer vs cancer)

30227001 21798257 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- cg2530110

cgl 1975790 (cancer+normal vs 10-373957 (cancer+normal vs

30853608 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- cgl 142399

cgl0661769 (cancer+normal vs 10-374010 (cancer+normal vs

30881484 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

7- cg0978263

cgl9272540 (cancer+normal vs 10-374092 (cancer+normal vs

15055459 7

cancer+normal) cancer+normal)

(cancer vs cancer)

7- 10- cg2265823

cg07748583 (cancer+normal vs (cancer vs cancer)

151157166 99566075 8

cancer+normal)

(cancer vs cancer)

7- 11- cg2668467

cgl3702357 (cancer+normal vs (cancer vs cancer)

75367549 122543428 3

cancer+normal)

(cancer vs cancer)

8- cg0337049

cgl3092738 (cancer+normal vs 11-1380305 (cancer vs cancer)

124498970 0

cancer+normal)

(cancer vs cancer)

8- cg2362876

cgl0855978 (cancer+normal vs 11-1380355 (cancer vs cancer)

23780241 0

cancer+normal)

(cancer vs cancer)

8- cgl325315

cg08169341 (cancer+normal vs 11-2826988 (cancer vs cancer)

48437852 3

cancer+normal)

(normal vs normal)

(cancer vs cancer)

8- cgO 167762 (cancer vs cancer) cg21205855 (cancer+normal vs 11-8361190

61563866 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 12- cg0625118

cg08620329 (cancer+normal vs (cancer+normal vs

67454546 109046825 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 12- cg2409090

cgl2109823 (cancer+normal vs (cancer+normal vs

67454595 12605470 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 12- cg0945132

cg21181453 (cancer+normal vs (cancer+normal vs

130700954 132639764 0

cancer+normal) cancer+normal)

(cancer vs cancer)

9- cgl384799

cgl4519997 (cancer+normal vs 12-6590163 (cancer vs cancer)

14321079 8

cancer+normal)

12- cg0734431

Status - Hypo (cancer vs cancer)

69054360 5

1- cgl9704755 (cancer vs cancer) 13- cg0321589 (cancer vs cancer) 10965094 (cancer+normal vs 100497610 5

cancer+normal)

(cancer vs cancer)

1- 13- cg2686224

cg23612220 (cancer+normal vs (cancer vs cancer)

151129298 100497665 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cg0356291

cg01903374 (cancer+normal vs (cancer+normal vs

151129844 100497789 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cgl993757

cg09319828 (cancer+normal vs (cancer+normal vs

156551787 101091946 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cg0639833

cg01010328 (cancer+normal vs (cancer+normal vs

156551873 101161616 5

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 13- cg0801925

cgl0016364 (cancer+normal vs (cancer vs cancer)

159770136 111980272 3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cgl698657

cg26394055 (cancer+normal vs (cancer+normal vs

161184921 114872102 1

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 13- cg0721012

cg07948875 (cancer+normal vs (cancer vs cancer)

169187004 44596411 3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cg2111912

cg23013029 (cancer+normal vs (cancer+normal vs

17508341 46297726 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cgl366253

cg24602411 (cancer+normal vs (cancer+normal vs

192515127 96202378 0

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 14- cg0827767

cgl8384097 (cancer+normal vs (cancer vs cancer)

202129566 104618028 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 14- cg0691891

cgl7744604 (cancer+normal vs (cancer+normal vs

206946166 39648415 8

cancer+normal) cancer+normal)

(cancer vs cancer)

1- cg0665443

cgl8854765 (cancer+normal vs 16-1946951 (cancer vs cancer)

74665362 1

cancer+normal)

(cancer vs cancer)

10- cg0054693

cg23130731 (cancer+normal vs 16-1947055 (cancer vs cancer)

105978651 2

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 16- cg0818634

cg00287536 (cancer+normal vs (cancer+normal vs

34925718 70563092 1

cancer+normal) cancer+normal)

(cancer vs cancer)

10- 16- cg0207157

cg00025044 (cancer+normal vs (cancer vs cancer)

50716478 88550450 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 17- cg0917356

cg04552555 (cancer+normal vs (cancer+normal vs

1680823 78878278 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 17- cg2267307

cgl8723409 (cancer+normal vs (cancer+normal vs

1911547 78878530 0

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 18- cgl879308

cgl 1822932 (cancer+normal vs (cancer vs cancer)

33913716 20735005 6

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 18- cg2355386

cg03106245 (cancer+normal vs (cancer+normal vs

47399980 74325812 7

cancer+normal) cancer+normal)

11- (cancer vs cancer) 18- cg0786713 (cancer vs cancer) cgl0511890

47416487 (cancer+normal vs 74325904 3 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

11- cg0796235

cg09739398 (cancer+normal vs 19-1307484 (cancer vs cancer)

47416886 8

cancer+normal)

(cancer vs cancer)

11- 19- cgl205518

cg24301930 (cancer+normal vs (cancer vs cancer)

65408496 35649055 3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cgl493841

cg07420137 (cancer+normal vs 19-3595702 (cancer+normal vs

65661516 9

cancer+normal) cancer+normal)

(cancer vs cancer)

11- cg0494828

cgl3980609 (cancer+normal vs 19-3595832 (cancer vs cancer)

66883117 6

cancer+normal)

(cancer vs cancer)

11- 2- cgl 192975

cgl0542975 (cancer+normal vs (cancer vs cancer)

67205096 130512167 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 2- cg0220452

cgl4088196 (cancer+normal vs (cancer+normal vs

70211408 138940416 1

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 2- cgl417577

cg25574765 (cancer+normal vs (cancer vs cancer)

70211531 180846309 7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 2- cgl651481

cgl6061668 (cancer+normal vs (cancer+normal vs

70257149 242766284 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 2- cgl938407

cgl 1194613 (cancer+normal vs (cancer+normal vs

70268728 242766412 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- cgl647285

cgl9369955 (cancer+normal vs 2-43598959 (cancer+normal vs

2030178 3

cancer+normal) cancer+normal)

(cancer vs cancer)

12- 20- cg0646672

cg08621624 (cancer+normal vs (cancer vs cancer)

2030223 42825248 8

cancer+normal)

(cancer vs cancer)

12- 20- cg0824685

cg02522196 (cancer+normal vs (cancer vs cancer)

44226393 62421310 9

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 3- cg0086229

cgl0590292 (cancer+normal vs (cancer+normal vs

51717674 178984973 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- cg0802890

cgl2353452 (cancer+normal vs 3-28889136 (cancer+normal vs

51717865 1

cancer+normal) cancer+normal)

(cancer vs cancer)

12- cg0948974

cgl4556909 (cancer+normal vs 3-41239648 (cancer vs cancer)

51718088 3

cancer+normal)

(cancer vs cancer)

12- cgl544839

cg08075204 (cancer+normal vs 3-57432946 (cancer vs cancer) 51718112 4

cancer+normal)

(cancer vs cancer)

13- cgl812304

cgl8571045 (cancer+normal vs 4-1022462 (cancer vs cancer)

113238006 J

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

14- cg0017589

cgl4191466 (cancer+normal vs 4-1578077 (cancer+normal vs

103440432 5

cancer+normal) cancer+normal)

(cancer vs cancer)

15- 4- cg0702550

cgl2042714 (cancer+normal vs (cancer vs cancer)

101715747 185913488 5

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16- 4- cg0439213

cg09866569 (cancer+normal vs (cancer+normal vs

2737340 190767168 3

cancer+normal) cancer+normal) (cancer vs cancer)

16- cgl774971

cg01681367 (cancer+normal vs 5-14915807

29676071 (cancer vs cancer)

0

cancer+normal)

(cancer vs cancer)

16- cgl0491452 5- cg2577740

(cancer+normal vs

88866627 (cancer vs cancer)

179643456 9

cancer+normal)

(cancer vs cancer)

17-263096 cg0237140

cg25045219 (cancer+normal vs 5-676784 (cancer vs cancer)

1

cancer+normal)

(cancer vs cancer)

17- cg0988475

cgO 1722297 (cancer+normal vs 5-677840

46190702 (cancer vs cancer)

6

cancer+normal)

(cancer vs cancer)

17- cg0545876

cg03649649 (cancer+normal vs 5-678009

56408197 (cancer vs cancer)

4

cancer+normal)

(cancer vs cancer)

17- cg0775212

cg26112797 (cancer+normal vs 5-70746259

56409011 (cancer vs cancer)

0

cancer+normal)

(cancer vs cancer)

17- cg2662473

cgl0530767 (cancer+normal vs 5-70746330

56409028 (cancer vs cancer)

2

cancer+normal)

(cancer vs cancer)

17- cg0245547

cg27366766 (cancer+normal vs 5-77146197

56565286 (cancer vs cancer)

1

cancer+normal)

(normal vs normal)

17- (cancer vs cancer) cgl703433

cg01883155 5-77146318

74565009 (cancer vs cancer)

(cancer+normal vs 1

cancer+normal)

(cancer vs cancer)

17- 6- cgl806752

cg20667480 (cancer+normal vs

77916768 (cancer vs cancer)

107114594 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 6- cgl726765

cg00523683 (cancer+normal vs

78748471 (cancer+normal vs

170411557 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 6- cg0502491

cg02185248 (cancer+normal vs

78748494 (cancer+normal vs

170531180 6

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer)

6- cg2209944

cg06153925 (cancer+normal vs

78755379 (cancer+normal vs

170531660 1

cancer+normal) cancer+normal)

(cancer vs cancer)

17-800745 6- cg2706865

cgl4235846 (cancer+normal vs (cancer vs cancer)

170531710 0

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cg2671588

cgl 1252953 (cancer+normal vs 6-34464251

80358829 (cancer+normal vs

3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 7- cg0376409

cg25490145 (cancer+normal vs

80358850 (cancer+normal vs

139690853 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 7- cg2362508

cg21465176 (cancer+normal vs

80358876 (cancer+normal vs

139690881 4

cancer+normal) cancer+normal)

(cancer vs cancer)

19- cg2614685

cgl5123730

13215387 (cancer+normal vs 7-1660603 (cancer vs cancer)

5

cancer+normal)

(cancer vs cancer)

19- cg03758011 cgl662430

(cancer+normal vs 7-28834178

46294482 (cancer vs cancer)

4

cancer+normal)

(cancer vs cancer)

2- cg0679576

cgl3821008 (cancer+normal vs 7-34941831

175499113 (cancer vs cancer)

8

cancer+normal) (cancer vs cancer)

2- cg2744326

cgl3468685 (cancer+normal vs 7-39298343 (cancer vs cancer)

68592737 5

cancer+normal)

(cancer vs cancer)

2- cg0944954

cgO 1987702 (cancer+normal vs 7-69246130 (cancer vs cancer)

74264707 3

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cg2261451

cg04195125 (cancer+normal vs 7-77492522 (cancer+normal vs

88327530 8

cancer+normal) cancer+normal)

(cancer vs cancer)

20- cg2731021

cg00916899 (cancer+normal vs 7-81240445 (cancer vs cancer)

35944932 9

cancer+normal)

(cancer vs cancer)

20- cg0414680

cgl4921416 (cancer+normal vs 8-2017571 (cancer vs cancer)

3693158 1

cancer+normal)

(cancer vs cancer)

21- cg0170633

cgl7122157 (cancer+normal vs 8-72872845 (cancer vs cancer)

44819445 4

cancer+normal)

(cancer vs cancer)

3- cg0541850

cg00828556 (cancer+normal vs 8-8898513 (cancer vs cancer)

196351986 8

cancer+normal)

(cancer vs cancer)

3- (cancer+normal vs

cg08052292 (cancer+normal vs

56789178 cancer+normal)

cancer+normal)

(cancer vs cancer)

4-1221838 cg26923863 (cancer+normal vs Status - Hyper

cancer+normal)

(cancer vs cancer) (normal vs normal)

1- cgl926402

5-1503763 cgl9503640 (cancer+normal vs (cancer+normal vs

162630153 8

cancer+normal) cancer+normal)

(cancer vs cancer)

5- 1- cg0619135 (cancer+normal vs cg05650238 (cancer+normal vs

55215955 172714273 7 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- 1- cg0219104

cgl8281939 (cancer+normal vs (cancer+normal vs

77783895 232940990 4

cancer+normal) cancer+normal)

(cancer vs cancer)

6- cgl290058 (cancer+normal vs cgl4564351 (cancer+normal vs 1-38260410

135644405 3 cancer+normal) cancer+normal)

(cancer vs cancer)

6- cgl204583 (cancer+normal vs cg02673417 (cancer+normal vs 1-8014224

137105249 3 cancer+normal) cancer+normal)

(cancer vs cancer)

6- 10- cg0097468 (cancer+normal vs cg07805500 (cancer+normal vs

151380818 113759413 5 cancer+normal) cancer+normal)

(cancer vs cancer)

6- 10- cg2724505 (cancer+normal vs cg09783253 (cancer+normal vs

157932130 122356491 6 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 10- cgl247402

cgl0799846 (cancer+normal vs (cancer+normal vs

158406044 124639132 3

cancer+normal) cancer+normal)

(cancer vs cancer)

6- 10- cg0901905 (cancer+normal vs cg07253384 (cancer+normal vs

166877002 124639167 2 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

6- 10- cgl919792 (normal vs normal) cg02287007 (cancer+normal vs

166877038 16566625 2 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

6- 10- cgl696620 (cancer+normal vs cg01247537 (cancer+normal vs

27842098 50603359 1 cancer+normal) cancer+normal) (cancer vs cancer) (normal vs normal)

6- cg0046336

cgl8113826 (cancer+normal vs 10-8103673 (cancer+normal vs

31583942 7

cancer+normal) cancer+normal)

(cancer vs cancer)

6- 11- cg2329961 (cancer+normal vs cg25953692 (cancer+normal vs

31695415 45102239 8 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 12- cgl 122541

cg03900314 (cancer+normal vs (cancer+normal vs

31695552 93966317 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 12- cg2212537

cgl3597051 (cancer+normal vs (cancer+normal vs

31695599 93966485 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- 16- cgl636470

cg09001226 (cancer+normal vs (cancer+normal vs

32155082 23724485 9

cancer+normal) cancer+normal)

(cancer+normal vs

(cancer vs cancer)

16- cg2705488 cancer+normal)

7-2773782 cg20336172 (cancer+normal vs

67276940 7 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cg0170358

7-2773812 cg26247093 (cancer+normal vs (cancer+normal vs

42030287 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cgl237320

7-3134557 cg09450197 (cancer+normal vs (cancer+normal vs

42091713 8

cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

7- (cancer vs cancer) 17- cg0487975

cg07573366 (cancer+normal vs

32802765 (cancer+normal vs 42091909 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cgl880159

7-5258357 cg20071624 (cancer+normal vs (cancer+normal vs

42092187 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cg2463864

7-6476003 cg06488150 (cancer+normal vs (cancer+normal vs

42092247 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cg2711681

7-6476110 cg08313420 (cancer+normal vs (cancer+normal vs

42092315 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 17- cg0837294

cg02609337 (cancer+normal vs (cancer+normal vs

134559320 42092370 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 17- cg0651138

cg26769700 (cancer+normal vs (cancer+normal vs

140945810 42092403 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 17- cgl225925

cgl8440839 (cancer+normal vs (cancer+normal vs

141609380 42092431 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 17- cgl384706

cg00015530 (cancer+normal vs (cancer+normal vs

145052950 42092450 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 17- cg0163519

cgl9021985 (cancer+normal vs (cancer+normal vs

22398190 42092472 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 17- cg2586828

cgl3555415 (cancer+normal vs (cancer+normal vs

134454249 42092488 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 17- cg0198613

cg20324199 (cancer+normal vs (cancer+normal vs

96080326 42092588 1

cancer+normal) cancer+normal)

(cancer+normal vs 17- cgl017931 (cancer vs cancer) cancer+normal) 58498871 5 (cancer+normal vs cancer+normal)

(cancer vs cancer) cg2596400

Status - Hyper 17-9479910 (cancer+normal vs

7

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cgl261088

cgl3476072 (cancer+normal vs 17-9479912 (cancer+normal vs

149908313 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg0539053

cg00777271 (cancer+normal vs 18-5238183

149908524 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cgl429106

cg24620905 (cancer+normal vs 18-5238200

149908781 (cancer+normal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cgl 525884

cg20812370 (cancer+normal vs 18-5238219

164581169 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg2075751

cg03466326 (cancer+normal vs 18-5238310

205270559 (cancer+normal vs

9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cgl088596

cg05352688 (cancer+normal vs 18-5238589

211643515 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg2131102

cg24686918 (cancer+normal vs 18-5238608

221613658 (cancer+normal vs

3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg2013424

cg05396897 (cancer+normal vs 18-5238708

247611448 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 19- cgl386152

cg09226051 (cancer+normal vs

247611502 (cancer+normal vs

50836391 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 19- cg0101735

cgl6400794 (cancer+normal vs

27709850 (cancer+normal vs

50836561 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 19- cg0325128

cg25607920 (cancer+normal vs

42384365 (cancer+normal vs

50836910 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 19- cg2695279

cg26038582 (cancer+normal vs

42384390 (cancer+normal vs

50860847 6

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 19- cgl215359

cg07865091 (cancer+normal vs

43814306 (cancer+normal vs

50861047 3

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 19- cg0529481 (cancer+normal vs cgl 8856478 (cancer+normal vs

43814358 53541287 3 cancer+normal) cancer+normal)

(cancer vs cancer)

1- 2- cgOO 16087 (cancer+normal vs cg08706567 (cancer+normal vs

43814983 106567892 2 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 2- cg0216985

cgl3393721 (cancer+normal vs

43815035 (cancer+normal vs

110969641 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 2- cg0857024

cgl 1748187 (cancer+normal vs

114713108 (cancer+normal vs

110969853 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 2- cg0325022

cg00159523 (cancer+normal vs

114713187 (cancer+normal vs

110970097 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 2- cg0906808

cg05576619 (cancer+normal vs

17391003 (cancer+normal vs

110970204 6

cancer+normal) cancer+normal) (cancer vs cancer) (cancer vs cancer)

10- 2- cgl036643

cgl l416811 (cancer+normal vs

63422630 (cancer+normal vs

110970249 9

cancer+normal) cancer+normal)

(cancer vs cancer)

10- 2- cg07643225 cg2265031

(cancer+normal vs (cancer+normal vs

63422633 118845443 5

cancer+normal) cancer+normal)

(cancer vs cancer)

10- 2- cg2294065

cgl4789659 (cancer+normal vs

(cancer+normal vs

63809073 168275428 5

cancer+normal) cancer+normal)

(cancer vs cancer)

10- 2- cg0253982

cgl6401465 (cancer+normal vs

(cancer+normal vs

63809170 197787991 9 cancer+normal) cancer+normal)

(cancer vs cancer)

10- cg0188738

cg20684110 (cancer+normal vs

(cancer+normal vs 2-81420861

64565750 8 cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer)

21- cg0035960

cgl2474798 (cancer+normal vs

64565772 38935977 (cancer+normal vs

4

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer)

21- cg2348475

cg04858631 (cancer+normal vs

74035570 38935991 (cancer+normal vs

5

cancer+normal) cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer) cgl618858

cg03677069 (cancer+normal vs 3-10206396

88718317 (cancer+normal vs

9

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) cgl800785

cg26681847 (cancer+normal vs 3-10206537

120208749 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) cg0443775

cgl 1180921 (cancer+normal vs 3-10206628

57090226 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) cg0500259

cgl6127573 (cancer+normal vs 3-10206633

57532299 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) cgl 102930

cgl3771313 (cancer+normal vs 3-10206731

72533295 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer) cg0277293

cgl3073224

117131523 (cancer+normal vs

125709198 5 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer)

3- cg2702069

cg01054110 (cancer+normal vs

125002332 169482358 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

12- (cancer vs cancer)

3- cg2083904

cgl6402452 (cancer+normal vs (cancer+normal vs

58129855 169482714 1

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer)

3- cgl549411

cg05892030 (cancer+normal vs

51431710 169482895 (cancer+normal vs

7

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) cgl559994

cgO 1424562 (cancer+normal vs

69256677 169482899 (cancer+normal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer)

3- cg0138976

cg06617636 (cancer+normal vs

69256690 169482968 (cancer+normal vs

1

cancer+normal) cancer+normal)

(cancer vs cancer)

14- 3- cgl752757

cg08169020 (cancer+normal vs

(cancer+normal vs

69256888 169483021 4

cancer+normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer)

3- cg2303650

cgl0099732 (cancer+normal vs

69256977 169483025 (cancer+normal vs

8

cancer+normal) cancer+normal)

15- cgl0078511 (cancer vs cancer) 3-44754398 cg0497432 (cancer+normal vs 39872032 (cancer+normal vs 3 cancer+normal) cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer) cgl010838

cg08433504

39872071 (cancer+normal vs 3-44770937 (cancer+normal vs

9

cancer+normal) cancer+normal)

(cancer vs cancer)

15- cg2557481

cg01359532 (cancer+normal vs

75045126 (cancer+normal vs 3-44770954

2 cancer+normal) cancer+normal)

(cancer vs cancer)

15- (cancer vs cancer) cg0207355

cg21238234

83879539 (cancer+normal vs 3-44770973 (cancer+normal vs

8

cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) cg2483768

cgl4301190

31159704 (cancer+normal vs 3-44771102 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

16- (cancer vs cancer) cg0293311

cg09316954

7687754 (cancer+normal vs 3-44771105

6 (cancer+normal vs

9

cancer+normal) cancer+normal)

(cancer vs cancer)

16- 791325

cg09642825 3-44771113 cgl (cancer+normal vs

87416230 (cancer+normal vs

9

cancer+normal) cancer+normal)

(cancer vs cancer)

16- 4- cg0372946

cg06330621 (cancer+normal vs

87525461 (cancer+normal vs

189931880 2 cancer+normal) cancer+normal)

(cancer vs cancer)

16- 4- cg0525553

cg08196561 (cancer+normal vs

87525539 (cancer+normal vs

189932474 7

cancer+normal) cancer+normal)

(cancer vs cancer)

17- cg0812503

cg24205387 (cancer+normal vs

1464972 (cancer+normal vs 4-21699373

1 cancer+normal) cancer+normal)

(cancer vs cancer)

17- cg2080969

cg22980156 (cancer+normal vs

15366916 (cancer+normal vs 4-2757764

0 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

17- cg0268034

cgl9458020 (normal vs normal)

38473119 (cancer+normal vs 4-4871525

1

cancer+normal) (cancer+normal vs cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer)

5- cg0105475

cgl9443920

40075879 (cancer+normal vs

138728685 5 (cancer+normal vs cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer)

5- cg2476186

cgl7179862

46681362 (cancer+normal vs (cancer+normal vs

138728704 7

cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer)

5- cg0513768

cg03803541

46681401 (cancer+normal vs (cancer+normal vs

138729068 0

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 5- cgl464067

cgl7697835 (cancer+normal vs

75283832 (cancer+normal vs 139494937 0 cancer+normal) cancer+normal)

(cancer vs cancer)

17- (cancer vs cancer) cgl598130

cgl2871285

76713379 (cancer+normal vs 5-87981894 (cancer+normal vs

5

cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cg2247821

cgl7126555

10445516 (cancer+normal vs 6-26043990 (cancer+normal vs

0

cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cgl743245

cg21631439

10736448 (cancer+normal vs 6-26045532 (cancer+normal vs

3

cancer+normal) cancer+normal)

(cancer vs cancer)

19- (cancer vs cancer) cg0763617

cg08846870

15568360 (cancer+normal vs 6-26045534 (cancer+normal vs

8

cancer+normal) cancer+normal)

19- cg23450038 (cancer vs cancer) 6-26045663 cg2543896 (cancer vs cancer) 2462961 (cancer+normal vs 3 (cancer+nonnal vs cancer+nonnal) cancer+normal)

(cancer vs cancer)

19- cgl019991 (cancer+normal vs cg05258935 (cancer+normal vs 6-26045987

39086923 3 cancer+normal) cancer+normal)

(cancer vs cancer)

19- cg0059875 (cancer+normal vs cg21869046 (cancer+normal vs 7-35291644

41225005 8 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- cg2463197

cg01057656 (cancer+normal vs 8-11059029 (cancer+nonnal vs 45281140 0

cancer+normal) cancer+normal)

(cancer vs cancer)

19- cgl421954 (cancer+nonnal vs cgl7100943 (cancer+normal vs 8-49442567

6459300 -»

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- cg2425537

cgl 1734329 (cancer+normal vs 8-65488069 (cancer+normal vs

7460671 1

cancer+normal) cancer+normal)

(cancer vs cancer)

19- cg2052707 (cancer+normal vs cg22568423 (cancer+normal vs 8-95906439

8590567 0 cancer+normal) cancer+normal)

(cancer vs cancer)

19- cg0679753

cg22987448 (cancer+nonnal vs

(cancer+normal vs 9-19127804

8591364 3 cancer+normal) cancer+normal)

(cancer vs cancer)

20- cg2123447 (cancer+normal vs cg23501964 (cancer+normal vs 9-92023797

19866810 1 cancer+normal) cancer+normal)

(cancer vs cancer)

20- cg20918393 (cancer+normal vs Status - Hypo

19867136

cancer+normal)

(cancer vs cancer) (normal vs normal)

22- 1- cgl417284

cg00147172 (cancer+normal vs (cancer+normal vs

46423604 112960391 6

cancer+normal) cancer+normal)

(cancer vs cancer)

22- 1- cg0416575 (cancer+nonnal vs cgl8982286 (cancer+normal vs

51136325 150448943 9 cancer+normal) cancer+nonnal)

(cancer vs cancer)

3- 1- cgl275959 (cancer+normal vs cg24627325 (cancer+normal vs

101882326 155181615 7 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- cg0576841

cg08979515 (cancer+normal vs (cancer+normal vs

111697575 174417967 9

cancer+normal) cancer+normal)

(cancer vs cancer)

3- 1- cgl 167803 (cancer+normal vs cgl3029400 (cancer+normal vs

141087190 183841259 9 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- 1- cg2657057

cg02524983 (cancer+normal vs (cancer+nonnal vs

188012918 220415655 4

cancer+nonnal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

3- 1- cg0718464

cg03534375 (cancer+normal vs (cancer+normal vs

57743163 233815158 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) cg0001593

cgl5172734 (cancer+normal vs 1-46921746 (cancer+normal vs

57743377 0

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- cg2097742

cg05601456 (cancer+normal vs 1-46921844

114900431 (cancer+nonnal vs

6

cancer+normal) cancer+normal)

(cancer vs cancer)

4- cgl 980067 (cancer+nonnal vs cgl0393744 (cancer+normal vs 1-86081701

159969703 0 cancer+normal) cancer+nonnal)

4- (cancer vs cancer) 10- cgO 145060 (cancer+normal vs cg26741686

186318356 (cancer+normal vs 116640938 0 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

4- 10- cgl985674

cg06704884 (cancer+normal vs (cancer+normal vs

40665353 124316636 9

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- 10- cgl862913

cg24100671 (cancer+normal vs (cancer+normal vs

10551547 131592435 2

cancer+normal) cancer+normal)

(cancer vs cancer)

5- 10- cgl917000 (cancer+normal vs cg27024654 (cancer+normal vs

133904674 17277756 9 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

5- cg2530110

cg26516362 (cancer+normal vs 10-373957 (cancer+normal vs

178986906 3

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer) cgl 142399

5-5271554 cg25485055 (cancer+normal vs 10-374010 (cancer+normal vs

8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

6- cg0978263

cgl3829419 (cancer+normal vs 10-374092 (cancer+normal vs

143167279 7

cancer+normal) cancer+normal)

(cancer vs cancer)

6- cg0667715 (cancer+normal vs cgl4296767 (cancer+normal vs 10-616959

30227001 1 cancer+normal) cancer+normal)

(cancer vs cancer)

6- 11- cgl042743 (cancer+normal vs cgl 1975790 (cancer+normal vs

30853608 12783675 0 cancer+normal) cancer+normal)

(cancer vs cancer)

6- 11- cgO 164626 (cancer+normal vs cgl0661769 (cancer+normal vs

30881484 14367071 8 cancer+normal) cancer+normal)

(cancer vs cancer)

7- cgl285163 (cancer+normal vs cgl9272540 (cancer+normal vs 11-2826951

15055459 5 cancer+normal) cancer+normal)

(normal vs normal)

(cancer vs cancer)

7- cgO 167762 (cancer vs cancer) cg07748583 (cancer+normal vs 11-8361190

151157166 8 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer)

7- cg0437253 (cancer+normal vs cgl3702357 (cancer+normal vs 11-968936

75367549 5 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 12- cg0625118

cgl3092738 (cancer+normal vs (cancer+normal vs

124498970 109046825 1

cancer+normal) cancer+normal)

(cancer vs cancer)

8- 12- cgl646588 (cancer+normal vs cgl0855978 (cancer+normal vs

23780241 113633320 2 cancer+normal) cancer+normal)

(cancer vs cancer)

8- 12- cg0948047 (cancer+normal vs cg08169341 (cancer+normal vs

48437852 124556975 0 cancer+normal) cancer+normal)

(cancer vs cancer)

8- 12- cg0148579 (cancer+normal vs cg21205855 (cancer+normal vs

61563866 124911358 0 cancer+normal) cancer+normal)

(cancer vs cancer)

8- 12- cgl250926 (cancer+normal vs cg08620329 (cancer+normal vs

67454546 124911444 8 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

8- 12- cg2409090

cgl2109823 (cancer+normal vs (cancer+normal vs

67454595 12605470 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

9- 12- cg0945132

cg21181453 (cancer+normal vs (cancer+normal vs

130700954 132639764 0

cancer+normal) cancer+normal)

9- (cancer vs cancer) 12- cgl348481 (cancer+normal vs cgl4519997

14321079 (cancer+normal vs 71862327 3 cancer+normal) 1 cancer+normal)

(cancer vs cancer)

13- cg0356291

Status - Hypo (cancer+normal vs

100497789 1

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cgl993757

cgl9704755 (cancer+normal vs (cancer+normal vs

10965094 101091946 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cg0639833

cg23612220 (cancer+normal vs (cancer+normal vs

151129298 101161616 5

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 13- cg2292668 (cancer+normal vs cg01903374 (cancer+normal vs

151129844 114799776 6 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cgl698657

cg09319828 (cancer+normal vs (cancer+normal vs

156551787 114872102 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cg2111912

cg01010328 (cancer+normal vs (cancer+normal vs

156551873 46297726 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 13- cgl366253

cgl0016364 (cancer+normal vs (cancer+normal vs

159770136 96202378 0

cancer+normal) cancer+normal)

(cancer vs cancer)

1- 13- cg0823662 (cancer+normal vs cg26394055 (cancer+normal vs

161184921 98126882 3 cancer+normal) cancer+normal)

(cancer vs cancer)

1- 14- cg2338314 (cancer+normal vs cg07948875 (cancer+normal vs

169187004 24909125 9 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

1- 14- cg0691891

cg23013029 (cancer+normal vs (cancer+normal vs

17508341 39648415 8

cancer+normal) cancer+normal)

(cancer vs cancer)

1- cg0632833 (cancer+normal vs cg24602411 (cancer+normal vs 16-1511419

192515127 8 cancer+normal) cancer+normal)

(cancer vs cancer)

1- 16- cg0130414 (cancer+normal vs cgl8384097 (cancer+normal vs

202129566 22296770 5 cancer+normal) cancer+normal)

(cancer vs cancer)

1- 16- cg2753538 (cancer+normal vs cgl7744604 (cancer+normal vs

206946166 30795743 0 cancer+normal) cancer+normal)

(cancer vs cancer)

1- 16- cgl038926 (cancer+normal vs cgl8854765 (cancer+normal vs

74665362 65789547 2 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 16- cg0399859

cg23130731 (cancer+normal vs (cancer+normal vs

105978651 69358580 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

10- 16- cg0818634

cg00287536 (cancer+normal vs (cancer+normal vs

34925718 70563092 1

cancer+normal) cancer+normal)

(cancer vs cancer)

10- 16- cg0100593 (cancer+normal vs cg00025044 (cancer+normal vs

50716478 84701635 7 cancer+normal) cancer+normal)

(cancer vs cancer)

11- 17- cg0143114 (cancer+normal vs cg04552555 (cancer+normal vs

1680823 35118924 0 cancer+normal) cancer+normal)

(cancer vs cancer)

11- 17- cgl522372 (cancer+normal vs cgl8723409 (cancer+normal vs

1911547 35119063 6 cancer+normal) cancer+normal)

(cancer vs cancer)

11- 17- cg2352682 (cancer+normal vs cgl 1822932 (cancer+normal vs

33913716 38245542 4 cancer+normal) cancer+normal) (cancer vs cancer)

11- 17- cgl277957 (cancer+normal vs cg03106245 (cancer+normal vs

47399980 62208434 5 cancer+normal) cancer+normal)

(cancer vs cancer)

11- 17- cg0188471 (cancer+normal vs cgl0511890 (cancer+normal vs

47416487 73316454 5 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 17- cg0917356

cg09739398 (cancer+normal vs (cancer+normal vs

47416886 78878278 5

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 17- cg2267307

cg24301930 (cancer+normal vs (cancer+normal vs

65408496 78878530 0

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 17- cg0609690 (cancer+normal vs cg07420137 (cancer+normal vs

65661516 78894393 1 cancer+normal) cancer+normal)

(cancer vs cancer)

11- 18- cgl710615 (cancer+normal vs cgl3980609 (cancer+normal vs

66883117 19410150 7 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 18- cg2355386

cgl0542975 (cancer+normal vs (cancer+normal vs

67205096 74325812 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- 18- cg0786713

cgl4088196 (cancer+normal vs (cancer+normal vs

70211408 74325904 3

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 19- cg0843780 (cancer+normal vs cg25574765 (cancer+normal vs

70211531 11304272 2 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

11- cgl493841

cgl6061668 (cancer+normal vs 19-3595702 (cancer+normal vs

70257149 9

cancer+normal) cancer+normal)

(cancer vs cancer)

11- 19- cg2369643 (cancer+normal vs cgl 1194613 (cancer+normal vs

70268728 45150725 2 cancer+normal) cancer+normal)

(cancer vs cancer)

12- cg0150478 (cancer+normal vs cgl9369955 (cancer+normal vs 19-6414019

2030178 4 cancer+normal) cancer+normal)

(cancer vs cancer)

12- cg0277541 (cancer+normal vs cg08621624 (cancer+normal vs 19-643457

2030223 7 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 2- cg0220452

cg02522196 (cancer+normal vs (cancer+normal vs

44226393 138940416 1

cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

12- 2- cg2285498

cgl0590292 (cancer+normal vs (cancer+normal vs

51717674 174082101 5

cancer+normal) cancer+normal)

(cancer vs cancer)

12- 2- cgl632612 (cancer+normal vs cgl2353452 (cancer+normal vs

51717865 240015886 3 cancer+normal) cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

12- 2- cg0400387 (cancer vs cancer) cgl4556909 (cancer+normal vs

51718088 241290895 1 (cancer+normal vs cancer+normal)

cancer+normal)

(cancer vs cancer) (cancer vs cancer)

12- 2- cgl651481

cg08075204 (cancer+normal vs (cancer+normal vs

51718112 242766284 8

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

13- 2- cgl938407

cgl8571045 (cancer+normal vs (cancer+normal vs

113238006 242766412 3

cancer+normal) cancer+normal)

(cancer vs cancer)

14- cg0032060 (cancer+normal vs cgl4191466 (cancer+normal vs 2-29116256

103440432 8 cancer+normal) cancer+normal) (cancer vs cancer)

15- cg0794809 (cancer+normal vs cgl2042714 (cancer+normal vs 2-3173279

101715747 5 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

16- cgl647285

cg09866569 (cancer+normal vs 2-43598959 (cancer+normal vs

2737340 3

cancer+normal) cancer+normal)

(cancer vs cancer)

16- 21- cg0293096 (cancer+normal vs cg01681367 (cancer+normal vs

29676071 46378243 3 cancer+normal) cancer+normal)

(cancer vs cancer)

16- 22- cgl219327 (cancer+normal vs cgl0491452 (cancer+normal vs

88866627 39547181 7 cancer+normal) cancer+normal)

(cancer vs cancer)

3- cgl873139 (cancer+normal vs

17-263096 cg25045219 (cancer+normal vs

123414733 8 cancer+normal) cancer+normal)

(cancer vs cancer)

17- 3- cg0852419 (cancer+normal vs cgO 1722297 (cancer+normal vs

46190702 128825270 0 cancer+normal) cancer+normal)

(cancer vs cancer)

17- 3- cg0892939 (cancer+normal vs cg03649649 (cancer+normal vs

56408197 151778972 9 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 3- cg0086229

cg26112797 (cancer+normal vs (cancer+normal vs 56409011 178984973 0

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 3- cg0725012 (cancer+normal vs cgl0530767 (cancer+normal vs

56409028 194833983 8 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cg0802890

cg27366766 (cancer+normal vs 3-28889136 (cancer+normal vs

56565286 1

cancer+normal) cancer+normal)

(normal vs normal)

(normal vs normal)

17- (cancer vs cancer) cg0405883

cg01883155 3-69732819 (cancer+normal vs

74565009 (cancer+normal vs 7

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- cg0017589

cg20667480 (cancer+normal vs 4-1578077 (cancer+normal vs

77916768 5

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 4- cg0003316 (cancer+normal vs cg00523683 (cancer+normal vs

78748471 169952114 5 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 4- cg0439213

cg02185248 (cancer+normal vs (cancer+normal vs

78748494 190767168 3

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 5- cg0732173 (cancer+normal vs cg06153925 (cancer+normal vs

78755379 179302907 0 cancer+normal) cancer+normal)

(cancer vs cancer)

cg2402022 (cancer+normal vs

17-800745 cgl4235846 (cancer+normal vs 5-64308317

2 cancer+normal) cancer+normal)

(cancer vs cancer) (normal vs normal)

17- cgl 119098

cgl 1252953 (cancer+normal vs 5-64334489 (cancer+normal vs

80358829 7

cancer+normal) cancer+normal)

(cancer vs cancer)

17- 6- cgl 150778 (cancer+normal vs cg25490145 (cancer+normal vs

80358850 138915521 0 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

17- 6- cgl726765

cg21465176 (cancer+normal vs (cancer+normal vs

80358876 170411557 4

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

19- 6- cg0502491

cgl5123730 (cancer+normal vs (cancer+normal vs

13215387 170531180 6

cancer+normal) cancer+normal) (cancer vs cancer) (cancer vs cancer)

19- 6- cg2209944

cg03758011 (cancer+normal vs (cancer+normal vs

46294482 170531660 1

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- cg2671588

cgl3821008 (cancer+normal vs 6-34464251 (cancer+normal vs

175499113 3

cancer+normal) cancer+normal)

(cancer vs cancer)

2- 7- cg2418356 (cancer+normal vs cgl3468685 (cancer+normal vs

68592737 101629430 6 cancer+normal) cancer+normal)

(cancer vs cancer)

2- 7- cg0855460 (cancer+normal vs cgO 1987702 (cancer+normal vs

74264707 120702049 3 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

2- 7- cg0376409

cg04195125 (cancer+normal vs (cancer+normal vs

88327530 139690853 2

cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

20- 7- cg2362508

cg00916899 (cancer+normal vs (cancer+normal vs

35944932 139690881 4

cancer+normal) cancer+normal)

(cancer vs cancer)

20- cg0472544 (cancer+normal vs cgl4921416 (cancer+normal vs 7-4807556

3693158 2 cancer+normal) cancer+normal)

(cancer vs cancer) (cancer vs cancer)

21- cg2261451

cgl7122157 (cancer+normal vs 7-77492522 (cancer+normal vs

44819445 8

cancer+normal) cancer+normal)

(cancer vs cancer)

3- cgl814464 (cancer+normal vs cg00828556 (cancer+normal vs 8-41113257

196351986 7 cancer+normal) cancer+normal)

(cancer vs cancer)

3- cg08052292 (cancer+normal vs (normal vs normal)

56789178

cancer+normal)

(cancer vs cancer)

4-1221838 cg26923863 (cancer+normal vs Status - Hyper

cancer+normal)

(cancer vs cancer)

1- cg0918056

5-1503763 cgl9503640 (cancer+normal vs (normal vs normal)

102308808 4

cancer+normal)

(cancer vs cancer)

5- 1- cgl772417

cg05650238 (cancer+normal vs (normal vs normal)

55215955 150552817 5

cancer+normal)

(cancer vs cancer)

5- cgl655282

cgl8281939 (cancer+normal vs 1-19278734 (normal vs normal)

77783895 2

cancer+normal)

(cancer vs cancer)

6- 1- cgl555812

cgl4564351 (cancer+normal vs (normal vs normal)

135644405 219347279 9

cancer+normal)

(cancer vs cancer)

6- 1- cg0322124

cg02673417 (cancer+normal vs (normal vs normal)

137105249 219347458 7

cancer+normal)

(cancer vs cancer)

6- 1- cg0044902

cg07805500 (cancer+normal vs (normal vs normal)

151380818 234658467 1

cancer+normal)

(cancer vs cancer)

6- cg0410095

cg09783253 (cancer+normal vs 1-94571619 (normal vs normal)

157932130 6

cancer+normal)

(cancer vs cancer)

6- 10- cg2643364

cgl0799846 (cancer+normal vs (normal vs normal)

158406044 12762778 0

cancer+normal)

(normal vs normal)

(cancer vs cancer)

6- 10- cgl919792 (normal vs normal) cg07253384 (cancer+normal vs

166877002 16566625 2 (cancer+normal vs cancer+normal)

cancer+normal) (cancer vs cancer) (normal vs normal) o- cg0046336

cg02287007 (cancer+normal vs 10-8103673 (cancer+normal vs

166877038 7

cancer+normal) cancer+normal)

(cancer vs cancer)

11- cgl240797

cg01247537 (cancer+normal vs (normal vs normal)

27842098 104817914 9

cancer+normal)

(cancer vs cancer)

o- 11- cgl096438

cgl8113826 (cancer+normal vs (normal vs normal)

31583942 20690223 5

cancer+normal)

(cancer vs cancer)

o- 11- cgl 192449

cg25953692 (cancer+normal vs (normal vs normal)

31695415 20934569 9

cancer+normal)

(cancer vs cancer)

o- 11- cgOl 16828

cg03900314 (cancer+normal vs (normal vs normal)

31695552 32421514 9

cancer+normal)

(cancer vs cancer)

o- 11- cg2044965

cgl3597051 (cancer+normal vs (normal vs normal)

31695599 32421752 9

cancer+normal)

(cancer vs cancer)

o- 11- cgl024466

cg09001226 (cancer+normal vs (normal vs normal)

32155082 32421808 6

cancer+normal)

(cancer vs cancer)

11- cg0486985

7-2773782 cg20336172 (cancer+normal vs (normal vs normal)

67186575 4

cancer+normal)

(cancer vs cancer)

12- cg2227797

7-2773812 cg26247093 (cancer+normal vs (normal vs normal)

108960008 2

cancer+normal)

(cancer vs cancer)

12- cg2111033

7-3134557 cg09450197 (cancer+normal vs (normal vs normal)

113671028 7

cancer+normal)

(normal vs normal)

7- (cancer vs cancer) 12- cgl 130294

cg07573366 (normal vs normal)

32802765 (cancer+normal vs 115133159 5

cancer+normal)

(cancer vs cancer)

12- cg0568471

7-5258357 cg20071624 (cancer+normal vs (normal vs normal)

130641648 5

cancer+normal)

(cancer vs cancer)

12- cgl782844

7-6476003 cg06488150 (cancer+normal vs (normal vs normal)

58150842 5

cancer+normal)

(cancer vs cancer)

12- cg0425796

7-6476110 cg08313420 (cancer+normal vs (normal vs normal)

74932579 9

cancer+normal)

(cancer vs cancer)

8- 12- cg0466145

cg02609337 (cancer+normal vs (normal vs normal)

134559320 92531553 7

cancer+normal)

(cancer vs cancer)

8- 13- cgl 136052

cg26769700 (cancer+normal vs (normal vs normal)

140945810 113379828 2

cancer+normal)

(cancer vs cancer)

8- 14- cg0982219

cgl8440839 (cancer+normal vs (normal vs normal)

141609380 24801191 2

cancer+normal)

(cancer vs cancer)

8- 14- cg2622999

cg00015530 (cancer+normal vs (normal vs normal)

145052950 24801301 0

cancer+normal)

(cancer vs cancer)

8- 14- cgl010177

cgl9021985 (cancer+normal vs (normal vs normal)

22398190 75894136 3

cancer+normal)

(cancer vs cancer)

15- cg2156542

cgl3555415 (cancer+normal vs (normal vs normal)

134454249 74592665 1

cancer+normal) (cancer vs cancer)

9- 15- cg2226086

cg20324199 (cancer+normal vs (normal vs normal)

96080326 92398112 9

cancer+normal)

UpRCaG (cancer vs 15- cg2723492

(normal vs normal) cancer) 97244292 9

16- cgl788695

Status - Hyper (normal vs normal)

56642024 9

(cancer vs cancer)

1- (cancer vs cancer) 17- cg0277085

cg20795569 (normal vs normal)

152085136 (cancer+normal vs 55533254 7

cancer+normal)

1- 17- cg2598821

cgl8018890 (cancer vs cancer) (normal vs normal)

33438854 79265759 4

1- 18- cg0158958

cg23012731 (cancer vs cancer) (normal vs normal)

33438978 77440800 0

(cancer vs cancer)

1- (cancer vs cancer) 19- cg2228259

cg26114324 (normal vs normal)

44401857 (cancer+normal vs 17514117 0

cancer+normal)

(cancer vs cancer)

1- (cancer vs cancer) 19- cg0856267

cgl8115627 (normal vs normal)

44401979 (cancer+normal vs 21860753 2

cancer+normal)

(cancer vs cancer)

1- (cancer vs cancer) 19- cgl l28419

cg23954153 (normal vs normal)

44402353 (cancer+normal vs 51190047 6

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 2- cg2015420

1-6546574 cg24535622 (normal vs normal)

(cancer+normal vs 128458240 6

cancer+normal)

10- (cancer vs cancer) 2- cgl366800

cg05291069 (normal vs normal)

126136435 (cancer vs cancer) 131278268 5

10- 2- cgl883813

cg08932440 (cancer vs cancer) (normal vs normal)

126136607 131357649 3

10- (cancer vs cancer) 2- cg0989465

cg06299833 (normal vs normal)

126136709 (cancer vs cancer) 132430151 5

10- 2- cgl279225

cg07062043 (cancer vs cancer) (normal vs normal)

60935910 133106819 0

10- 2- cg0838423

cg26014391 (cancer vs cancer) (normal vs normal)

60936451 160041968 9

10- 2- cgl429845

cgl3686115 (cancer vs cancer) (normal vs normal)

60936626 177012117 7

10- (cancer vs cancer) 2- cgl599097

cgl3262165 (normal vs normal)

95326801 (cancer vs cancer) 177012372 2

(cancer vs cancer)

10- 2- cgl950939

cg04115659 (cancer+normal vs (normal vs normal)

98480124 177016490 3

cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) 2- cg0526656

cg01948390 (normal vs normal)

22850866 (cancer+normal vs 177024502 4

cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) 2- cg2367630

cg03988778 (normal vs normal)

22850891 (cancer+normal vs 177025859 2

cancer+normal)

11- 2- cg0793053

cg21064916 (cancer vs cancer) (normal vs normal)

44340839 177025975 9

(cancer vs cancer)

12- 2- cg2454142

cg24281668 (cancer vs cancer) (normal vs normal)

113661270 177029459 6

(cancer+normal vs cancer+normal)

12- (cancer vs cancer) 2- cgl015963

cgl7405840 (normal vs normal)

24717001 (cancer vs cancer) 177037364 0

13- 2- cgl305365

cgl 1337289 (cancer vs cancer) (normal vs normal)

96294131 177037631 3

(cancer vs cancer)

14- (cancer vs cancer) 2- cg2394061

cgl6322262 (normal vs normal)

59931110 (cancer+normal vs 218898788 2

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 2- cg0611709

cg22821834 (normal vs normal)

59931541 (cancer+normal vs 240291657 3

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) cg0862735

cgl5436096 2-60778395 (normal vs normal)

59931922 (cancer+normal vs 2

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) cgO 114606

cg09859398 2-80549973 (normal vs normal)

59932033 (cancer+normal vs 3

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 20- cg2530153

cg04186360 (normal vs normal)

59932101 (cancer+normal vs 43378953 2

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 20- cg0276784 (cancer vs cancer) cgl4847688

59932113 (cancer+normal vs 45986173 1 (normal vs normal) cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 20- cg0778173

cg05217962 (normal vs normal)

59932128 (cancer+normal vs 55839008 6

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 20- cg0396042

cg01678172 (normal vs normal)

59932146 (cancer+normal vs 57042304 4

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 22- cgl390989

cg21893185 (normal vs normal)

59932153 (cancer+normal vs 51066142 5

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) 3- cgl223578

cgl6411251 (normal vs normal)

59932250 (cancer+normal vs 123476518 8

cancer+normal)

(cancer vs cancer)

14- (cancer vs cancer) cgl880826

cgl0014563 3-18464935 (normal vs normal)

59932273 (cancer+normal vs 1

cancer+normal)

15- 4- cg0165394

cg24498031 (cancer vs cancer) (normal vs normal)

40545050 152967131 2

15- 4- cg2274407

cgl3892980 (cancer vs cancer) (normal vs normal)

40545143 155410860 9

15- 4- cg0812575

cgl8097281 (cancer vs cancer) (normal vs normal)

40545145 174422908 5

15- cg0667313

cgl2635019 (cancer vs cancer) 4-778924 (normal vs normal)

40545175 0

15- _C g0544840

cg04305879 (cancer vs cancer) 4-779173 (normal vs normal)

40545215 4

15- cg0854332

cg05068428 (cancer vs cancer) 5-1108651 (normal vs normal)

40545296 7 16- (cancer vs cancer) cg2624483

cg09350341 5-1110226 (normal vs normal)

55514378 (cancer vs cancer) 8

16- (cancer vs cancer) 5- cg0981525

cgl0026203 (normal vs normal)

66878654 (cancer vs cancer) 113029364 1

16- (cancer vs cancer) 5- cgl230321

cg06524479 (normal vs normal)

66878676 (cancer vs cancer) 138923267 5

16- (cancer vs cancer) 5- cg0419274

cgl0373196 (normal vs normal)

66878685 (cancer vs cancer) 171605778 0

16- (cancer vs cancer) 5- cg2221049

_C g05440435 (normal vs normal)

66878687 (cancer vs cancer) 175561172 7

16- 5- cg0465252

cg05552717 (cancer vs cancer) (normal vs normal)

66878871 179124978 2

(cancer vs cancer)

17- (cancer vs cancer) cgl810113

cgl6276850 5-4942469 (normal vs normal)

38498914 (cancer+normal vs 8

cancer+normal)

17- (cancer vs cancer) cgl737355

cg24704730 5-72594735 (normal vs normal)

42061328 (normal vs normal) 4

17- (cancer vs cancer) cgl514378

cg22298430 5-92909434 (normal vs normal)

5404330 (cancer vs cancer) 8

17- (cancer vs cancer) cgl777485

cg27230784 5-92929319 (normal vs normal)

5404337 (cancer vs cancer) 1

(cancer vs cancer)

17- (cancer vs cancer) cg2544948

cgl8671949 5-92929372 (normal vs normal) 5404581 (cancer+normal vs 4

cancer+normal)

17- cg0824147

cg04886642 (cancer vs cancer) 5-92929573 (normal vs normal)

72920359 7

17- (cancer vs cancer) cg0956008

cg25306087 5-92930634 (normal vs normal)

72920362 (cancer vs cancer) 2

(cancer vs cancer)

17- cgl829023

cg06353318 (cancer+normal vs 5-92931173 (normal vs normal)

72920378 3

cancer+normal)

17- cgl830778

cgl2483561 (cancer vs cancer) 5-92931623 (normal vs normal)

72920385 3

17- (cancer vs cancer) cg0880205

cg09461395 5-92932045 (normal vs normal)

72920598 (cancer vs cancer) 3

18- (cancer vs cancer) cg0753342

cgl7012181 5-92935283 (normal vs normal)

47087419 (cancer vs cancer) 2

18- cg2273680

cg27113059 (cancer vs cancer) 5-92938149 (normal vs normal)

47088248 7

19- cg0682062

cg26626525 (cancer vs cancer) 5-92938232 (normal vs normal)

12163582 1

19- cg0970372

cg06899953 (cancer vs cancer) 7-69447465 (normal vs normal)

12163679 7

(cancer vs cancer)

19- (cancer vs cancer) 8- cg2475979

cgl8816098 (normal vs normal)

18335182 (cancer+normal vs 114444356 5

cancer+normal)

19- cg0610648

cg03100040 (cancer vs cancer) 8-32985289 (normal vs normal)

37341870 4

19- cgl518663

cgl9396867 (cancer vs cancer) 8-49231688 (normal vs normal)

40314862 8

19- (cancer vs cancer) cg2230308

cg06528584 8-49352435 (normal vs normal)

40314899 (cancer vs cancer) 3

19- (cancer vs cancer) cgl459568

cg06936564 8-77592946 (normal vs normal)

40314927 (cancer vs cancer) 3

19- cg0717160

cg00498691 (cancer vs cancer) 8-91640288 (normal vs normal)

40315143 9

19- (cancer vs cancer) cgl433212

cgl0788735 8-97657097 (normal vs normal)

46974886 (cancer vs cancer) 0 (cancer vs cancer)

19- 9- cg0306605

cgl9660239 (cancer+normal vs (normal vs normal)

53400545 110249749 0

cancer+normal)

19- 9- cgl401821

cg01620580 (cancer vs cancer) (normal vs normal)

53696649 140173347 5

(cancer vs cancer)

2- (cancer vs cancer) 9- cg0938173

cgl9702675 (normal vs normal)

171387064 (cancer+normal vs 140173549 7

cancer+normal)

2- (cancer vs cancer)

cg24603464 Status - Hypo

238395852 (cancer vs cancer)

(normal vs normal)

21- 1- cgl417284

cg09556952 (cancer vs cancer) (cancer+normal vs

38119946 112960391 6

cancer+normal)

21- 1- cgl654904

cgl 1631644 (cancer vs cancer) (normal vs normal)

46131923 156050126 3

22- (cancer vs cancer) 1- cg2602087

cgl9343611 (normal vs normal) 28010528 (cancer vs cancer) 172352681 8

22- 1- cgl908110

cg21789136 (cancer vs cancer) (normal vs normal)

37213466 203156625 1

22- 1- cg0815998

cgl3836638 (cancer vs cancer) (normal vs normal)

42679804 205326071 9

(cancer vs cancer)

3- (cancer vs cancer) 1- cgl345921

cg09008417 (normal vs normal)

42814854 (cancer+normal vs 205326437 7

cancer+normal)

(cancer vs cancer)

3- (cancer vs cancer) 1- cgl415967

cg27409478 (normal vs normal)

75834335 (cancer+normal vs 205819179 2

cancer+normal)

4- (cancer vs cancer) 1- cgl489316

cg21943416 (normal vs normal)

143766916 (cancer vs cancer) 205819251 1

4- (cancer vs cancer) 1- cgl l96591

cg00183107 (normal vs normal)

143767118 (cancer vs cancer) 205819406 3

1- cg0951592

5-1155853 cg26330510 (cancer vs cancer) (normal vs normal)

221057558 1

(cancer vs cancer) 1- cgl659138

5-1594676 cg21167402 (normal vs normal)

(cancer vs cancer) 245499719 1

(cancer vs cancer)

cg0677329

5-1594678 cg24960960 (cancer vs cancer) 1-3028577 (normal vs normal)

5

(normal vs normal)

(cancer vs cancer)

cg2718755

5-1594715 cg21931717 (cancer vs cancer) 1-3269252 (normal vs normal)

5

(normal vs normal)

(normal vs normal)

5- (cancer vs cancer) cg0923445 (cancer vs cancer) cg20780811 1-94560697

170289021 (cancer vs cancer) 4 (cancer+normal vs

cancer+normal)

5- cg0103335

cg02320454 (cancer vs cancer) 10-1402917 (normal vs normal)

94956017 6

(cancer vs cancer)

6- (cancer vs cancer) cg2487261

cg27369401 10-3158994 (normal vs normal)

166722053 (cancer+normal vs 0

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 10- cg0344232

cg02151625 (normal vs normal)

166722060 (cancer+normal vs 33524393 2

cancer+normal)

(cancer vs cancer)

6- 10- cg2405720

cgl3045351 (cancer vs cancer) (normal vs normal)

28092048 87682317 4

(cancer+normal vs cancer+normal)

(cancer vs cancer)

6- 11- cg0034772

cg00567696 (cancer+normal vs (normal vs normal)

46097521 102651753 9

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 11- cg2282128

cg23634318 (normal vs normal)

46097671 (cancer+normal vs 115581830 9

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cgl000286

cg06768203 11-1482176 (normal vs normal)

46097695 (cancer+normal vs 0

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) cg0494864

cg08211306 11-1901748 (normal vs normal)

46097784 (cancer+normal vs 9

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cg0156253

cg24507266 (normal vs normal)

145027948 (cancer+normal vs 44899805 7

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cg0906173

cg06452769 (normal vs normal)

145028093 (cancer+normal vs 57364841 3

cancer+normal)

(cancer vs cancer)

8- (cancer vs cancer) 11- cg2521879

cgl4234406 (normal vs normal)

145028103 (cancer+normal vs 68472905 7

cancer+normal)

(normal vs normal)

8- cgO 167762 (cancer vs cancer) cg00450319 (cancer vs cancer) 11-8361190

37605978 8 (cancer+normal vs cancer+normal)

(cancer vs cancer)

9- (cancer vs cancer) 12- cg0814304

cgl3439181 (normal vs normal)

35757158 (cancer+normal vs 124929704 6

cancer+normal)

(cancer vs cancer)

9- (cancer vs cancer) 13- cg2584964

cg20227976 (normal vs normal)

35757314 (cancer+normal vs 112627458 2

cancer+normal)

(cancer vs cancer)

(cancer vs cancer) 13- cgl560574

9-4299830 cgl3513288 (normal vs normal)

(cancer+normal vs 113797929 4

cancer+normal)

(cancer vs cancer)

(cancer vs cancer)

9- 13- cg2665038

cg07852402 (normal vs normal) (normal vs normal)

96713643 29290660 3

(cancer+normal vs

cancer+normal)

9- (cancer vs cancer) 13- cg0860599

cgl3398482 (normal vs normal)

96715256 (normal vs normal) 46426238 1

13- cgl943236

Status - Hypo (normal vs normal)

46426263 2

1- (cancer vs cancer) 13- cgl053316

cgl6401490 (normal vs normal)

10704953 (cancer vs cancer) 99174312 1

1- (cancer vs cancer) 14- cgl011536

cg07790752 (normal vs normal)

147101904 (cancer vs cancer) 100435663 8

(cancer vs cancer) 15- cgl984724

1-1564422 cg00078456 (normal vs normal)

(cancer vs cancer) 58246538 4

(cancer vs cancer) 15- cg2645630

1-1564920 cgl7122213 (normal vs normal)

(cancer+normal vs 62917317 4 cancer+normal)

1- cgl038569

cgl0313278 (cancer vs cancer) 16-1175678 (normal vs normal)

15681735 2

(cancer vs cancer)

1- (cancer vs cancer) cg0030079

cgl0230257 16-1231723 (normal vs normal)

161928549 (cancer+normal vs 4

cancer+normal)

1- cg0840170

cgl 1687863 (cancer vs cancer) 16-1493637 (normal vs normal)

162337248 3

(cancer vs cancer)

1- (cancer vs cancer) cg0235165

cgl2486795 16-4442918 (normal vs normal)

162337320 (cancer+normal vs 5

cancer+normal)

1- 16- cg0258361

cg06475894 (cancer vs cancer) (normal vs normal)

223567955 54407990 8

1- 16- cg0434092

cg24846680 (cancer vs cancer) (normal vs normal)

228362309 55067613 8

1- (cancer vs cancer) 16- cgl668289

cgl8277682 (normal vs normal)

228362509 (cancer vs cancer) 85508110 9

(cancer vs cancer) cg0581381

1-2303963 cgl8106803 16-875966 (normal vs normal)

(cancer vs cancer) 8

(cancer vs cancer)

1- (cancer vs cancer) 16- cg0368256

cg25211006 (normal vs normal)

43971496 (cancer+normal vs 88738418 8

cancer+normal)

1- 16- cg0076283

cg22035229 (cancer vs cancer) (normal vs normal)

76262648 88990161 0

1- 17- cg0359450

cgl7028301 (cancer vs cancer) (normal vs normal)

76262711 10002773 6

10- (cancer vs cancer) 17- cgl 149288

_C g03444838 (normal vs normal)

1156482 (cancer vs cancer) 13899286 6

(cancer vs cancer)

10- (cancer vs cancer) 17- cg0901592

cg04784635 (normal vs normal)

116097581 (cancer+normal vs 17714347 1

cancer+normal)

(cancer vs cancer)

10- (cancer vs cancer) 17- cg2294621

cg24075136 (normal vs normal)

29578013 (cancer+normal vs 17714414 9

cancer+normal)

(cancer vs cancer)

10- cgl971398

cgl6862260 (cancer+normal vs 17-3791952 (normal vs normal)

88445516 0

cancer+normal)

10- (cancer vs cancer) 17- cg2714235

cgl 1322432 (normal vs normal)

95847671 (cancer vs cancer) 53713264 4

(cancer vs cancer)

11- (cancer vs cancer) 17- cgl827230

cg02376282 (normal vs normal)

1543206 (cancer+normal vs 74160634 7

cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) 17- cgl406047

cg08373904 (normal vs normal)

1543275 (cancer+normal vs 80573287 1

cancer+normal)

(cancer vs cancer)

11- 18- cgl820860

cg08129093 (cancer+normal vs (normal vs normal)

17803389 10488229 2

cancer+normal)

(cancer vs cancer)

11- (cancer vs cancer) 18- cg0359919

cg05584439 (normal vs normal)

47213196 (cancer+normal vs 33485300 7

cancer+normal)

11- 18- cg0770423

cg04113632 (cancer vs cancer) (normal vs normal)

67892272 46501202 5 11- (cancer vs cancer) cg2442865

cg24121967 19-3942217 (normal vs normal)

69089119 (cancer vs cancer) 3

11- cg2441943

cgl3226797 (cancer vs cancer) 19-4446031 (normal vs normal)

78053252 6

12- 2- cgl870306

cg03600432 (cancer vs cancer) (normal vs normal)

109006223 105363536 6

12- 2- cgl302476

cg25201101 (cancer vs cancer) (normal vs normal)

131355465 121487296 1

(cancer vs cancer)

12- (cancer vs cancer) cgl991143

cg07896667 2-16430654 (normal vs normal)

1726076 (cancer+normal vs 0

cancer+normal)

(normal vs normal)

12- 2- cg2285498

cgl9224639 (cancer vs cancer) (cancer+normal vs

28186450 174082101 5

cancer+normal)

13- (cancer vs cancer) cgl623379

cgl3370010 2-20001490 (normal vs normal)

33743647 (cancer vs cancer) 7

15- (cancer vs cancer) 2- cg2573056

cgl4101284 (normal vs normal)

63062631 (cancer vs cancer) 236100751 4

16- 20- cg0635730

cg05881753 (cancer vs cancer) (normal vs normal)

57759992 48183673 5

16- 21- cgl943419

cg27078786 (cancer vs cancer) (normal vs normal)

66887815 48018608 9

16- 22- cg2267772

cgl8642576 (cancer vs cancer) (normal vs normal)

74752765 20229013 3

(cancer vs cancer)

16- (cancer vs cancer) cg2215612

cg00838040 3-10327453 (normal vs normal)

84446919 (cancer+normal vs 8

cancer+normal)

16- (cancer vs cancer) cg2058167

cg00308659 3-24887420 (normal vs normal)

84871952 (cancer vs cancer) 4

(normal vs normal)

(cancer vs cancer) cg0405883

16-928338 cg09080920 3-69732819 (cancer+normal vs

(cancer vs cancer) 7

cancer+normal)

17- (cancer vs cancer) cg2069430

cg23019125 4-3948578 (normal vs normal)

78820391 (cancer vs cancer) 3

17- cgl075421

cg01902059 (cancer vs cancer) 4-8073804 (normal vs normal) 80671131 5

17- 5- cg2703950

cg07847788 (cancer vs cancer) (normal vs normal)

8128726 150029215 1

5- cg0663515

18-580228 cg20731110 (cancer vs cancer) (normal vs normal)

171094937 0

19- (cancer vs cancer) 5- cg2564519

cgl3964781 (normal vs normal)

14552350 (cancer vs cancer) 171533681 9

(cancer vs cancer)

2- (cancer vs cancer) cg2736909

cg09468399 5-2169769 (normal vs normal)

240008233 (cancer+normal vs 6

cancer+normal)

(cancer vs cancer)

2- (cancer vs cancer) cgl978163

cgl7774001 5-77935323 (normal vs normal)

25600752 (cancer+normal vs 7

cancer+normal)

2- 6- cgl015649

cg21005412 (cancer vs cancer) (normal vs normal)

29149902 124857134 3

2- (cancer vs cancer) 6- cg0761968

cgl2055459 (normal vs normal)

97652489 (cancer vs cancer) 152126080 3

2- (cancer vs cancer) 6- cg0718996

cgl3571852 (normal vs normal)

97652491 (cancer vs cancer) 152126092 2

20- (cancer vs cancer) 6- cgl304672

cgl5032960 (normal vs normal)

56888536 (cancer vs cancer) 167655053 4

22- cg08425796 (cancer vs cancer) 6- cg2733344 (normal vs normal) 50981121 (cancer vs cancer) 167680455 1

3- cg2563797

cg08723913 (cancer vs cancer) 6-17116181 (normal vs normal)

114035950 2

3- (cancer vs cancer) cgl874774

cgl7572056 6-19180751 (normal vs normal)

195947062 (cancer vs cancer) 2

4- (cancer vs cancer) cg2016122

cg01266375 6-31980836 (normal vs normal)

129643491 (cancer vs cancer) 7

4- (cancer vs cancer) cg2195010

cg06676006 6-37109522 (normal vs normal)

151179898 (cancer vs cancer) 7

5- (cancer vs cancer) cg0714834

cg03898832 6-43714275 (normal vs normal)

140868130 (cancer vs cancer) 1

5- (cancer vs cancer) cgl652385

cgl4105467 6-54156824 (normal vs normal)

149675916 (cancer vs cancer) 0

(cancer vs cancer)

5- 7- cg2709293

cg20748242 (cancer+normal vs (normal vs normal)

175955925 100744067 5

cancer+normal)

7- cgl512770

5-421733 cg00976097 (cancer vs cancer) (normal vs normal)

101079617 2

(cancer vs cancer)

(cancer vs cancer) cg0420648

5-465330 cgl5026243 7-1121657 (normal vs normal)

(cancer+normal vs 4

cancer+normal)

cgO 142276

5-465665 cgl 1869150 (cancer vs cancer) 7-1369374 (normal vs normal)

7

6- (cancer vs cancer) 7- cgl854104

cg05368910 (normal vs normal)

134911061 (cancer vs cancer) 140227195 2

6- (cancer vs cancer) 7- cgl367572

cg00273754 (normal vs normal)

14305310 (cancer vs cancer) 140227273 1

6- (cancer vs cancer) 7- cg2144369

cg09484852 (normal vs normal)

157939700 (cancer vs cancer) 142637936 9

(cancer vs cancer)

6- (cancer vs cancer) 7- cg2232632

cgl0584587 (normal vs normal)

163730283 (cancer+normal vs 151142178 8

cancer+normal)

6- (cancer vs cancer) 7- cg0351018

cg00664730 (normal vs normal)

168393930 (cancer vs cancer) 155580742 6

(cancer vs cancer)

6- (cancer vs cancer) 8- cg0723669

cgl9527959 (normal vs normal)

168394191 (cancer+normal vs 120599284 1

cancer+normal)

(cancer vs cancer)

6- (cancer vs cancer) 9- cgl458291

cgl4041603 (normal vs normal)

168394198 (cancer+normal vs 132262821 7

cancer+normal)

6- (cancer vs cancer)

cgl0367069

168394477 (cancer vs cancer)

(cancer vs cancer)

6- (cancer vs cancer)

cg06251420

168684623 (cancer+normal vs

cancer+normal)

6- cg03126567 (cancer vs cancer)

169689773

(cancer vs cancer)

(cancer vs cancer)

6-6971315 cgl8679635

(cancer+normal vs

cancer+normal)

(cancer vs cancer)

6-6971335 cg09146892 (cancer+normal vs

cancer+normal)

(normal vs normal)

6-6971371 cgl9751937

(cancer vs cancer) (cancer vs cancer)

(cancer+normal vs cancer+normal)

(cancer vs cancer)

7-1102344 (cancer vs cancer) cgl2692727

(cancer+normal vs cancer+normal)

7- cg04876978

112431576 (cancer vs cancer)

7- cg27053157

149257723 (cancer vs cancer)

7- cgl8753341

157202405 (cancer vs cancer)

(cancer vs cancer)

7- (cancer vs cancer) cgl8362281

157204364 (cancer+normal vs cancer+normal)

7- (cancer vs cancer) cg07993586

157204960 (cancer vs cancer)

7-1936854 cg00236141 (cancer vs cancer)

7-1937120 (cancer vs cancer) cg04326741

(cancer vs cancer)

7-5682666 cg08180025 (cancer vs cancer)

7-8002109 cg06640047 (cancer vs cancer)

7- cgl6781484

88425758 (cancer vs cancer)

7- cg08533136

94924376 (cancer vs cancer)

7- (cancer vs cancer) cg22798737

94927713 (cancer vs cancer)

8- (cancer vs cancer) cg06258648

100708621 (cancer vs cancer)

8- (cancer vs cancer) cg22533992

119344904 (cancer vs cancer)

8- cg25555098

144462851 (cancer vs cancer)

8- (cancer vs cancer) cgl6530595

144788492 (cancer vs cancer)

(cancer vs cancer)

8- (cancer vs cancer) cg24513449

145599544 (cancer+normal vs cancer+normal)

8- (cancer vs cancer) cgl8811093

145758588 (cancer vs cancer)

8- cg03521348

40319233 (cancer vs cancer)

(cancer vs cancer)

9- (cancer vs cancer) cgl4173587

139907691 (cancer+normal vs cancer+normal)

9- cgl4341551

139913237 (cancer vs cancer)

9- cgl3461130

140401576 (cancer vs cancer)

9- (cancer vs cancer) cgl3858974

86149293 (cancer vs cancer)

9- (cancer vs cancer) cgl 9989242

96069142 (cancer vs cancer)

9- (cancer vs cancer) cgl4505733

96069195 (cancer vs cancer)