Title:
MICRO-FLUIDIC CHIP, DEVICE AND METHOD FOR CHEMILUMINESCENT IMMUNOASSAY
Document Type and Number:
WIPO Patent Application WO/2019/007036
Kind Code:
A1
Abstract:
A micro-fluidic chip, device and method for chemiluminescent immunoassay. The micro-fluidic chip comprises: a bottom plate (6), and a first liquid inlet channel (1), a second liquid inlet channel (2), a third liquid inlet channel (3), an immune reaction tank (4), and a light-emitting reaction pool (5) formed on a first surface of the bottom plate. A discharging end of the immune reaction pool (4) is communicated with a liquid inlet end of the light-emitting reaction pool (5), and a primer (9) is provided in the immune reaction pool (4). The primer (9) is used for fixing an antigen-antibody complex generated in the immune reaction pool (4). A liquid outlet end of the first liquid inlet channel (1) is communicated with the liquid inlet end of the immune reaction pool (4), and the first fluid inlet channel (1) is used for introducing the antigen and antibody to be tested into the immune response pool (4). The liquid outlet end of the second liquid inlet channel (2) is communicated with the liquid inlet end of the immune response pool (4), and the second liquid inlet channel (2) is used for introducing an alkaline solution into the immune response pool (4).The liquid outlet end of the third liquid inlet channel (3) is communicated with the liquid inlet end of the light-emitting reaction pool (5), and the third liquid inlet channel (3) is used for introducing an oxidant solution into the light-emitting reaction pool (5).
Inventors:
YANG ZHAOKUN (CN)
QIU YUN (CN)
LIU SHA (CN)
SUN XIAO (CN)
QIU YUN (CN)
LIU SHA (CN)
SUN XIAO (CN)
Application Number:
PCT/CN2018/073606
Publication Date:
January 10, 2019
Filing Date:
January 22, 2018
Export Citation:
Assignee:
BOE TECHNOLOGY GROUP CO LTD (CN)
BEIJING BOE DISPLAY TECH CO (CN)
BEIJING BOE DISPLAY TECH CO (CN)
International Classes:
G01N21/76; B01L3/00; G01N33/542
Foreign References:
| CN105241870A | 2016-01-13 | |||
| US20120295290A1 | 2012-11-22 | |||
| US20150111306A1 | 2015-04-23 | |||
| CN105241871A | 2016-01-13 |
Other References:
KO-WEI CHANG ET AL.: "An Integrated Microfluidic System for Measurement of Glycated Hemoglobin Levels by Using an Aptamer-Antibody Assay on Magnetic Beads", BIOSENSORS AND BIOELECTRONICS, vol. 68, 31 December 2015 (2015-12-31), pages 397 - 403, XP055561928
Attorney, Agent or Firm:
CHINA PATENT AGENT (H.K.) LTD. (CN)
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