Title:
MICROARRAY, METHOD FOR MANUFACTURING MICROARRAY, INSPECTION METHOD, AND INSPECTION KIT
Document Type and Number:
WIPO Patent Application WO/2017/130829
Kind Code:
A1
Abstract:
The present invention provides a microarray with which it is possible to simultaneously react a blood sample and a plurality of types of reagent red blood cells in the same reaction phase, and that enables detection and identification of irregular antibodies in a simple manner and at a high sensitivity. This microarray for detecting and identifying irregular antibodies in a blood sample is characterized in that sets of red blood cells or red blood cell ghosts presenting a known antigen on the cell surface are immobilized in a regular arrangement on a substrate. This inspection method for inspecting irregular antibodies in a blood sample is provided with: a step for bringing a blood sample collected from a subject into contact with the microarray and performing a first antigen-antibody interaction; a step for cleaning the microarray, bringing a labeled anti-human antibody into contact therewith, and performing a second antigen-antibody interaction; and a step for detecting the labeled anti-human antibody.
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Inventors:
HACHIMURA KAZUO (JP)
NAGASHIO RYO (JP)
SATO YUICHI (JP)
OTANI SHINICHI (JP)
KANOH YUHSAKU (JP)
NAGASHIO RYO (JP)
SATO YUICHI (JP)
OTANI SHINICHI (JP)
KANOH YUHSAKU (JP)
Application Number:
PCT/JP2017/001724
Publication Date:
August 03, 2017
Filing Date:
January 19, 2017
Export Citation:
Assignee:
SCHOOL JURIDICAL PERSON THE KITASATO INST (JP)
International Classes:
G01N33/53; C12M1/34; C12Q1/02; G01N33/50; G01N33/80; G01N37/00
Domestic Patent References:
| WO2015124947A1 | 2015-08-27 |
Foreign References:
| JP2010523995A | 2010-07-15 | |||
| JP2012194068A | 2012-10-11 | |||
| JP2007147662A | 2007-06-14 |
Attorney, Agent or Firm:
TANAI Sumio et al. (JP)
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