Title:
MICROBIAL BIOTRANSFORMATION OF AROMATIC ACIDS TO THEIR REDUCED CARBON AROMATIC ACIDS
Document Type and Number:
WIPO Patent Application WO/2014/045298
Kind Code:
A3
Abstract:
The present invention relates to a method for microbial fermentation and biotransformation of aromatic acids to aromatic acids with reduced carbon atoms of wide commercial importance using a culture of actinomycete species. Amycolatopsis sp or the mutant thereof is employed in the present invention to convert natural as well as synthetic aromatic acids to reduced carbon aromatic acids with wide applications. The said culture in the disclosed invention is adapted to grow at 37-46°C to achieve the biotransformation of aromatic acid to reduced carbon aromatic acid is accomplished at 37-46°C to obtain a higher yield of the product.
Inventors:
YEOLE MAHENDRA M (IN)
GALA APARNA (IN)
LALI ARVIND M (IN)
GALA APARNA (IN)
LALI ARVIND M (IN)
Application Number:
PCT/IN2013/000525
Publication Date:
May 22, 2014
Filing Date:
August 28, 2013
Export Citation:
Assignee:
PRIVI BIOTECHNOLOGIES PRIVATE LTD (IN)
YEOLE MAHENDRA M (IN)
YEOLE MAHENDRA M (IN)
International Classes:
C12P7/42
Foreign References:
| US6133003A | 2000-10-17 | |||
| EP2157184A1 | 2010-02-24 | |||
| US20130115667A1 | 2013-05-09 |
Other References:
ACHTERHOLT ET AL: "Identification of Amycolatopsis sp. strain HR167 genes, involve in the bioconversion of ferulic acid to vanillin", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER VERLAG, BERLIN, DE, vol. 54, no. 6, 1 January 2000 (2000-01-01), pages 799 - 807, XP002263786, ISSN: 0175-7598, DOI: 10.1007/S002530000431
B. MAX ET AL: "Decarboxylation of Ferulic Acid to 4-Vinyl Guaiacol by Streptomyces setonii", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY ; PART A: ENZYME ENGINEERING AND BIOTECHNOLOGY, HUMANA PRESS INC, NEW YORK, vol. 166, no. 2, 12 November 2011 (2011-11-12), pages 289 - 299, XP035002245, ISSN: 1559-0291, DOI: 10.1007/S12010-011-9424-7
MUHEIM A ET AL: "Towards a high-yield bioconversion of ferulic acid to vanillin", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER VERLAG, BERLIN, DE, vol. 51, no. 4, 30 April 1999 (1999-04-30), pages 456 - 461, XP008101165, ISSN: 0175-7598, DOI: 10.1007/S002530051416
SUTHERLAND J B ET AL: "METABOLISM OF CINNAMIC, P-COUMARIC, AND FERULIC ACIDS BY STREPTOMYCES SETONII", CANADIAN JOURNAL OF MICROBIOLOGY, NRC RESEARCH PRESS, CA, vol. 29, no. 10, 1 January 1983 (1983-01-01), pages 1253 - 1257, XP000650324, ISSN: 0008-4166
J. R. DAVIS ET AL: "Genome Sequence of Amycolatopsis sp. Strain ATCC 39116, a Plant Biomass-Degrading Actinomycete", JOURNAL OF BACTERIOLOGY, vol. 194, no. 9, 9 April 2012 (2012-04-09), pages 2396 - 2397, XP055106586, ISSN: 0021-9193, DOI: 10.1128/JB.00186-12
E GRUND ET AL: "Catabolism of Benzoate and Monohydroxylated Benzoates by Amycolatopsis and Streptomyces spp", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1 May 1990 (1990-05-01), pages 1459 - 1464, XP055106390, Retrieved from the Internet [retrieved on 20140310]
TIMMANAGOUDA B. KAREGOUDAR AND CHI-KYUNG KIM: "MICROBIAL DEGRADATION OF MONOHYDROXYBENZOIC ACIDS", THE JOURNAL OF MICROBIOLOGY, vol. 38, no. 2, June 2000 (2000-06-01), pages 53 - 61, XP002721506
"Amycolatopsis sp. Atcc, 39116", 11 March 2014 (2014-03-11), pages 1 - 2, XP002721507, Retrieved from the Internet [retrieved on 20140311]
C. FLEIGE ET AL: "Investigation of the Amycolatopsis sp. Strain ATCC 39116 Vanillin Dehydrogenase and Its Impact on the Biotechnical Production of Vanillin", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 79, no. 1, 12 October 2012 (2012-10-12), pages 81 - 90, XP055106412, ISSN: 0099-2240, DOI: 10.1128/AEM.02358-12
B. MAX ET AL: "Decarboxylation of Ferulic Acid to 4-Vinyl Guaiacol by Streptomyces setonii", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY ; PART A: ENZYME ENGINEERING AND BIOTECHNOLOGY, HUMANA PRESS INC, NEW YORK, vol. 166, no. 2, 12 November 2011 (2011-11-12), pages 289 - 299, XP035002245, ISSN: 1559-0291, DOI: 10.1007/S12010-011-9424-7
MUHEIM A ET AL: "Towards a high-yield bioconversion of ferulic acid to vanillin", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER VERLAG, BERLIN, DE, vol. 51, no. 4, 30 April 1999 (1999-04-30), pages 456 - 461, XP008101165, ISSN: 0175-7598, DOI: 10.1007/S002530051416
SUTHERLAND J B ET AL: "METABOLISM OF CINNAMIC, P-COUMARIC, AND FERULIC ACIDS BY STREPTOMYCES SETONII", CANADIAN JOURNAL OF MICROBIOLOGY, NRC RESEARCH PRESS, CA, vol. 29, no. 10, 1 January 1983 (1983-01-01), pages 1253 - 1257, XP000650324, ISSN: 0008-4166
J. R. DAVIS ET AL: "Genome Sequence of Amycolatopsis sp. Strain ATCC 39116, a Plant Biomass-Degrading Actinomycete", JOURNAL OF BACTERIOLOGY, vol. 194, no. 9, 9 April 2012 (2012-04-09), pages 2396 - 2397, XP055106586, ISSN: 0021-9193, DOI: 10.1128/JB.00186-12
E GRUND ET AL: "Catabolism of Benzoate and Monohydroxylated Benzoates by Amycolatopsis and Streptomyces spp", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1 May 1990 (1990-05-01), pages 1459 - 1464, XP055106390, Retrieved from the Internet
TIMMANAGOUDA B. KAREGOUDAR AND CHI-KYUNG KIM: "MICROBIAL DEGRADATION OF MONOHYDROXYBENZOIC ACIDS", THE JOURNAL OF MICROBIOLOGY, vol. 38, no. 2, June 2000 (2000-06-01), pages 53 - 61, XP002721506
"Amycolatopsis sp. Atcc, 39116", 11 March 2014 (2014-03-11), pages 1 - 2, XP002721507, Retrieved from the Internet
C. FLEIGE ET AL: "Investigation of the Amycolatopsis sp. Strain ATCC 39116 Vanillin Dehydrogenase and Its Impact on the Biotechnical Production of Vanillin", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 79, no. 1, 12 October 2012 (2012-10-12), pages 81 - 90, XP055106412, ISSN: 0099-2240, DOI: 10.1128/AEM.02358-12
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